Details of the Probe

General Information of Probe

Probe ID
LDPC0326
Probe Name
C070
Synonyms
Z4286591341
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 328.4
Lipid-water partition coefficient (xlogp) 2.9
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C17H20N4OS
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-2,4-dicyclopropyl-1,3-thiazole-5-carboxamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)C2=C(N=C(S2)C3CC3)C4CC4
InChI
InChI=1S/C17H20N4OS/c1-2-3-8-17(20-21-17)9-10-18-15(22)14-13(11-4-5-11)19-16(23-14)12-6-7-12/h1,11-12H,3-10H2,(H,18,22)
InChIKey
NSOXMRCVRDZKGK-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

133 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 13.74  LDD1766 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 25.46  LDD1766 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 15.35  LDD1766 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 21.56  LDD1766 
Acid ceramidase (ASAH1) LDTP05905 29.45  LDD1766 
Activin receptor type-1B (ACVR1B) LDTP03822 14.12  LDD1766 
Adenosine deaminase (ADA) LDTP01803 48.17  LDD1766 
ADP-dependent glucokinase (ADPGK) LDTP11127 19.16  LDD1766 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 20.11  LDD1766 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 10.85  LDD1766 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 16.80  LDD1766 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 12.73  LDD1766 
Atlastin-2 (ATL2) LDTP09251 9.00  LDD1766 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 9.19  LDD1766 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 17.15  LDD1766 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 8.51  LDD1766 
Beta-galactosidase (GLB1) LDTP02837 11.96  LDD1766 
Beta-glucuronidase (GUSB) LDTP02260 8.69  LDD1766 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 11.24  LDD1766 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 13.83  LDD1766 
Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) LDTP00462 11.63  LDD1766 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 15.45  LDD1766 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 14.32  LDD1766 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 26.17  LDD1766 
Ceramide glucosyltransferase (UGCG) LDTP06617 14.62  LDD1766 
Ceramide synthase 2 (CERS2) LDTP10329 13.45  LDD1766 
Choline kinase alpha (CHKA) LDTP03787 10.93  LDD1766 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) LDTP08933 8.63  LDD1766 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 10.41  LDD1766 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 10.63  LDD1766 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 16.91  LDD1766 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 25.63  LDD1766 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 37.27  LDD1766 
Cytochrome b-c1 complex subunit Rieske, mitochondrial (UQCRFS1) LDTP04144 13.55  LDD1766 
Cytochrome b5 type B (CYB5B) LDTP00697 30.06  LDD1766 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 20.53  LDD1766 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 11.08  LDD1766 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 10.70  LDD1766 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 10.78  LDD1766 
Delta(14)-sterol reductase TM7SF2 (TM7SF2) LDTP01389 21.56  LDD1766 
Delta(24)-sterol reductase (DHCR24) LDTP06375 14.93  LDD1766 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 8.75  LDD1766 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 8.46  LDD1766 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 13.18  LDD1766 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 13.27  LDD1766 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 13.93  LDD1766 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 18.64  LDD1766 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 10.56  LDD1766 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 17.03  LDD1766 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 14.22  LDD1766 
Epoxide hydrolase 1 (EPHX1) LDTP02175 17.15  LDD1766 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 23.59  LDD1766 
Ferrochelatase, mitochondrial (FECH) LDTP03198 32.00  LDD1766 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 42.52  LDD1766 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 11.00  LDD1766 
Heme oxygenase 1 (HMOX1) LDTP02359 39.95  LDD1766 
Heme oxygenase 2 (HMOX2) LDTP03540 62.68  LDD1766 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 11.88  LDD1766 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 17.27  LDD1766 
Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) LDTP08532 10.85  LDD1766 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 9.25  LDD1766 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 22.63  LDD1766 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 9.65  LDD1766 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 34.06  LDD1766 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 15.67  LDD1766 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 10.27  LDD1766 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 11.55  LDD1766 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 16.80  LDD1766 
Lysosomal acid phosphatase (ACP2) LDTP02539 10.13  LDD1766 
Lysosomal alpha-glucosidase (GAA) LDTP02486 9.78  LDD1766 
Lysosomal cobalamin transporter ABCD4 (ABCD4) LDTP00404 8.51  LDD1766 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.18  LDD1766 
Lysosomal protective protein (CTSA) LDTP02505 21.26  LDD1766 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 20.11  LDD1766 
Macrophage migration inhibitory factor (MIF) LDTP02713 11.71  LDD1766 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 17.39  LDD1766 
Minor histocompatibility antigen H13 (HM13) LDTP09396 11.08  LDD1766 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 13.83  LDD1766 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 13.09  LDD1766 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 8.57  LDD1766 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 18.51  LDD1766 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 20.53  LDD1766 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 8.57  LDD1766 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 8.46  LDD1766 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 39.12  LDD1766 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 8.82  LDD1766 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 18.38  LDD1766 
NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) LDTP01983 18.13  LDD1766 
NADPH--cytochrome P450 reductase (POR) LDTP02848 8.75  LDD1766 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 26.91  LDD1766 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 13.83  LDD1766 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 10.70  LDD1766 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 10.78  LDD1766 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 9.13  LDD1766 
Phospholipase A2 group XV (PLA2G15) LDTP09088 9.99  LDD1766 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 10.41  LDD1766 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 19.84  LDD1766 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 14.03  LDD1766 
Prostaglandin reductase 1 (PTGR1) LDTP06227 9.78  LDD1766 
Prostaglandin reductase 3 (PTGR3) LDTP15422 8.88  LDD1766 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 11.71  LDD1766 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 9.99  LDD1766 
Protein O-GlcNAcase (OGA) LDTP00988 11.00  LDD1766 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 16.34  LDD1766 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 9.78  LDD1766 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 14.22  LDD1766 
Ras-related protein Rab-24 (RAB24) LDTP10020 9.85  LDD1766 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 11.55  LDD1766 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 24.59  LDD1766 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 9.25  LDD1766 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 13.74  LDD1766 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 19.56  LDD1766 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 13.09  LDD1766 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 10.27  LDD1766 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 17.88  LDD1766 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 28.25  LDD1766 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 10.48  LDD1766 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 25.11  LDD1766 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 19.84  LDD1766 
Sphingosine kinase 2 (SPHK2) LDTP12490 11.79  LDD1766 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 16.11  LDD1766 
Squalene monooxygenase (SQLE) LDTP06142 8.75  LDD1766 
Squalene synthase (FDFT1) LDTP03842 15.67  LDD1766 
Sulfotransferase 1A4 (SULT1A4) LDTP02431 99.73  LDD1766 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 12.55  LDD1766 
TLC domain-containing protein 1 (TLCD1) LDTP10182 14.32  LDD1766 
Trimethyllysine dioxygenase, mitochondrial (TMLHE) LDTP12679 8.75  LDD1766 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 19.56  LDD1766 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) LDTP07756 9.06  LDD1766 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 9.99  LDD1766 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 9.51  LDD1766 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 44.63  LDD1766 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 12.13  LDD1766 
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⏷ Show the Full List of 133 Enzyme
94 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 9.25  LDD1766 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 21.11  LDD1766 
Amyloid-beta precursor protein (APP) LDTP02071 8.51  LDD1766 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 13.00  LDD1766 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 30.06  LDD1766 
BRI3-binding protein (BRI3BP) LDTP15648 34.54  LDD1766 
Calcium uptake protein 1, mitochondrial (MICU1) LDTP11041 14.93  LDD1766 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 11.00  LDD1766 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 9.85  LDD1766 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 20.25  LDD1766 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 12.30  LDD1766 
Derlin-1 (DERL1) LDTP11245 12.21  LDD1766 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 24.08  LDD1766 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 55.33  LDD1766 
Etoposide-induced protein 2.4 homolog (EI24) LDTP00405 11.71  LDD1766 
Gasdermin-E (GSDME) LDTP00970 11.88  LDD1766 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 11.08  LDD1766 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 13.18  LDD1766 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 13.27  LDD1766 
Hippocampus abundant transcript-like protein 1 (MFSD14B) LDTP07063 8.82  LDD1766 
Integral membrane protein 2B (ITM2B) LDTP13833 10.70  LDD1766 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 11.55  LDD1766 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 9.92  LDD1766 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 13.36  LDD1766 
Lysosome membrane protein 2 (SCARB2) LDTP06034 28.44  LDD1766 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 9.06  LDD1766 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 13.00  LDD1766 
Major facilitator superfamily domain-containing protein 10 (MFSD10) LDTP06198 9.99  LDD1766 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 11.63  LDD1766 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 10.41  LDD1766 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 21.11  LDD1766 
Metaxin-1 (MTX1) LDTP05900 39.12  LDD1766 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 10.48  LDD1766 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 8.63  LDD1766 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 9.99  LDD1766 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 11.79  LDD1766 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 12.73  LDD1766 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 14.83  LDD1766 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 13.45  LDD1766 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 62.68  LDD1766 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 59.30  LDD1766 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 11.16  LDD1766 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 9.65  LDD1766 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 20.39  LDD1766 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 37.27  LDD1766 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 10.78  LDD1766 
Mpv17-like protein 2 (MPV17L2) LDTP14952 25.99  LDD1766 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 11.96  LDD1766 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 10.56  LDD1766 
Nucleoporin NDC1 (NDC1) LDTP11213 14.32  LDD1766 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 9.32  LDD1766 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 12.21  LDD1766 
Prosaposin (PSAP) LDTP02215 30.91  LDD1766 
Protein FAM8A1 (FAM8A1) LDTP16190 8.46  LDD1766 
Protein GPR107 (GPR107) LDTP07236 14.83  LDD1766 
Protein GPR108 (GPR108) LDTP12383 13.55  LDD1766 
Protein tweety homolog 3 (TTYH3) LDTP11615 27.28  LDD1766 
Protein wntless homolog (WLS) LDTP07156 16.91  LDD1766 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 16.56  LDD1766 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 19.29  LDD1766 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 12.55  LDD1766 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 16.11  LDD1766 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 14.03  LDD1766 
Sideroflexin-4 (SFXN4) LDTP07531 23.26  LDD1766 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 11.55  LDD1766 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 37.53  LDD1766 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 12.30  LDD1766 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 29.45  LDD1766 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 46.85  LDD1766 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 9.58  LDD1766 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 18.51  LDD1766 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 17.15  LDD1766 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 24.76  LDD1766 
Stomatin (STOM) LDTP03380 12.13  LDD1766 
Surfeit locus protein 4 (SURF4) LDTP00592 10.56  LDD1766 
Target of Myb1 membrane trafficking protein (TOM1) LDTP01051 8.57  LDD1766 
Tetraspanin-3 (TSPAN3) LDTP16813 30.27  LDD1766 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 24.59  LDD1766 
Translocator protein (TSPO) LDTP03546 15.67  LDD1766 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 27.28  LDD1766 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 13.93  LDD1766 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 20.11  LDD1766 
Transmembrane protein 104 (TMEM104) LDTP17797 11.55  LDD1766 
Transmembrane protein 126A (TMEM126A) LDTP15948 47.18  LDD1766 
Transmembrane protein 160 (TMEM160) LDTP20002 18.90  LDD1766 
Transmembrane protein 199 (TMEM199) LDTP08881 33.36  LDD1766 
Transmembrane protein 205 (TMEM205) LDTP07667 63.56  LDD1766 
Transmembrane protein 230 (TMEM230) LDTP10065 12.82  LDD1766 
Transmembrane protein 87A (TMEM87A) LDTP15481 14.42  LDD1766 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 14.83  LDD1766 
Vang-like protein 1 (VANGL1) LDTP09288 17.39  LDD1766 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 44.32  LDD1766 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 27.67  LDD1766 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 10.63  LDD1766 
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⏷ Show the Full List of 94 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 16.00  LDD1766 
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1 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Membrane progestin receptor alpha (PAQR7) LDTP15303 45.89  LDD1766 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 10.85  LDD1766 
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71 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 9.45  LDD1766 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 12.38  LDD1766 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD1766 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 10.93  LDD1766 
Centrin-2 (CETN2) LDTP03926 12.82  LDD1766 
Centromere protein K (CENPK) LDTP11143 19.70  LDD1766 
Clustered mitochondria protein homolog (CLUH) LDTP14486 15.14  LDD1766 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 26.35  LDD1766 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 14.32  LDD1766 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 13.00  LDD1766 
Emerin (EMD) LDTP04356 8.94  LDD1766 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 21.86  LDD1766 
Galanin peptides (GAL) LDTP03175 19.70  LDD1766 
Gamma-tubulin complex component 4 (TUBGCP4) LDTP13230 8.51  LDD1766 
Ganglioside GM2 activator (GM2A) LDTP02927 10.20  LDD1766 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 17.03  LDD1766 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 8.88  LDD1766 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 12.13  LDD1766 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 9.38  LDD1766 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 8.46  LDD1766 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 8.69  LDD1766 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 8.51  LDD1766 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 9.71  LDD1766 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 11.24  LDD1766 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 12.30  LDD1766 
Kinetochore protein Spc24 (SPC24) LDTP09069 8.57  LDD1766 
Kinetochore-associated protein 1 (KNTC1) LDTP04382 11.00  LDD1766 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 8.51  LDD1766 
Large proline-rich protein BAG6 (BAG6) LDTP04094 12.47  LDD1766 
Large ribosomal subunit protein uL22m (MRPL22) LDTP12736 8.88  LDD1766 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 39.67  LDD1766 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 13.45  LDD1766 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 9.78  LDD1766 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 32.22  LDD1766 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 64.00  LDD1766 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 23.92  LDD1766 
Neudesin (NENF) LDTP13630 9.06  LDD1766 
Neuferricin (CYB5D2) LDTP15623 16.91  LDD1766 
Nicastrin (NCSTN) LDTP09787 8.82  LDD1766 
Nucleobindin-1 (NUCB1) LDTP05375 9.19  LDD1766 
Nucleobindin-2 (NUCB2) LDTP05160 31.56  LDD1766 
Nurim (NRM) LDTP08606 17.27  LDD1766 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 9.25  LDD1766 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 12.91  LDD1766 
Protein CEBPZOS (CEBPZOS) LDTP18883 68.12  LDD1766 
Protein FAM114A2 (FAM114A2) LDTP16080 14.62  LDD1766 
Protein FAM162A (FAM162A) LDTP10056 18.51  LDD1766 
Protein FAM3C (FAM3C) LDTP09773 8.57  LDD1766 
Protein jagunal homolog 1 (JAGN1) LDTP08904 12.04  LDD1766 
Protein Mis18-beta (OIP5) LDTP00775 11.31  LDD1766 
Protein unc-119 homolog A (UNC119) LDTP05868 26.35  LDD1766 
Protein YIF1A (YIF1A) LDTP01494 11.39  LDD1766 
Protein YIF1B (YIF1B) LDTP06948 9.99  LDD1766 
RAD50-interacting protein 1 (RINT1) LDTP07476 17.51  LDD1766 
Reticulocalbin-2 (RCN2) LDTP06097 12.47  LDD1766 
Reticulon-3 (RTN3) LDTP01522 19.70  LDD1766 
Reticulon-4 (RTN4) LDTP12412 15.78  LDD1766 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 13.74  LDD1766 
Sorting nexin-9 (SNX9) LDTP14172 8.57  LDD1766 
Synaptogyrin-2 (SYNGR2) LDTP00859 8.69  LDD1766 
Syntaxin-10 (STX10) LDTP00986 14.83  LDD1766 
Syntaxin-18 (STX18) LDTP13086 25.99  LDD1766 
Tetraspanin-6 (TSPAN6) LDTP14458 12.91  LDD1766 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 20.53  LDD1766 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 17.15  LDD1766 
TraB domain-containing protein (TRABD) LDTP19963 14.03  LDD1766 
Transmembrane protein 209 (TMEM209) LDTP18272 13.83  LDD1766 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 19.29  LDD1766 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 43.71  LDD1766 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 8.46  LDD1766 
Vimentin (VIM) LDTP02297 11.47  LDD1766 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1766 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587