General Information of Experiment

Probe Name C094  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 166 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11127  ADP-dependent glucokinase (ADPGK) 99.7
 LDTP02359  Heme oxygenase 1 (HMOX1) 99.7
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 99.7
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 95.0
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 93.7
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 91.1
 LDTP01065  E3 ubiquitin-protein ligase TRIM13 (TRIM13) 90.5
 LDTP00697  Cytochrome b5 type B (CYB5B) 89.9
 LDTP03540  Heme oxygenase 2 (HMOX2) 80.4
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 79.9
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 79.9
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 79.3
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 78.8
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 74.5
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 69.6
 LDTP10329  Ceramide synthase 2 (CERS2) 66.7
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 64.0
 LDTP09095  Diacylglycerol lipase-beta (DAGLB) 62.7
 LDTP10038  Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1) 62.2
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 62.2
 LDTP06142  Squalene monooxygenase (SQLE) 61.4
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 60.5
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 59.3
 LDTP00836  ATPase GET3 (GET3) 58.9
 LDTP06977  GPI ethanolamine phosphate transferase 2 (PIGG) 57.3
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 56.9
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 56.5
 LDTP11957  Protein O-mannose kinase (POMK) 55.7
 LDTP03145  Catechol O-methyltransferase (COMT) 52.7
 LDTP12763  Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) 52.7
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 52.3
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 52.3
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 48.8
 LDTP01649  Phosphatidate cytidylyltransferase 2 (CDS2) 48.2
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 47.5
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 47.2
 LDTP13352  GTP:AMP phosphotransferase AK3, mitochondrial (AK3) 46.9
 LDTP01329  Lathosterol oxidase (SC5D) 46.2
 LDTP12293  Adipocyte plasma membrane-associated protein (APMAP) 45.6
 LDTP07931  Heme A synthase COX15 (COX15) 45.6
 LDTP15480  Prenylcysteine oxidase-like (PCYOX1L) 45.6
 LDTP15962  Protein-L-histidine N-pros-methyltransferase (METTL9) 44.6
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 44.3
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 43.4
 LDTP16070  Epimerase family protein SDR39U1 (SDR39U1) 43.1
 LDTP10966  Microsomal glutathione S-transferase 2 (MGST2) 43.1
 LDTP01986  NADH-ubiquinone oxidoreductase chain 5 (MT-ND5) 43.1
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 42.5
 LDTP04581  Holocytochrome c-type synthase (HCCS) 41.9
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 41.9
 LDTP12253  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) 41.6
 LDTP11284  Phosphatidylserine synthase 2 (PTDSS2) 41.6
 LDTP09060  Ubiquitin-associated domain-containing protein 2 (UBAC2) 41.6
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 41.6
 LDTP10020  Ras-related protein Rab-24 (RAB24) 41.1
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 40.8
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 40.8
 LDTP04289  Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) 40.8
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 39.9
 LDTP11852  Presenilin-associated rhomboid-like protein, mitochondrial (PARL) 39.7
 LDTP00758  Thioredoxin-like protein 1 (TXNL1) 39.1
 LDTP09666  Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) 38.6
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 38.3
 LDTP02000  3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) 37.8
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 37.8
 LDTP13986  Vesicle transport protein GOT1B (GOLT1B) 37.8
 LDTP06657  2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) 37.0
 LDTP13959  Dehydrogenase/reductase SDR family member 7 (DHRS7) 37.0
 LDTP09251  Atlastin-2 (ATL2) 36.8
 LDTP04531  Hexokinase-2 (HK2) 36.8
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 36.5
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 34.8
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 34.8
 LDTP11199  DCN1-like protein 5 (DCUN1D5) 34.5
 LDTP07591  Neutral cholesterol ester hydrolase 1 (NCEH1) 34.1
 LDTP03163  Sterol carrier protein 2 (SCP2) 33.8
 LDTP14278  Sulfide:quinone oxidoreductase, mitochondrial (SQOR) 33.8
 LDTP08232  Glycerol-3-phosphate acyltransferase 4 (GPAT4) 33.4
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 32.9
 LDTP05337  Dihydroorotate dehydrogenase (quinone), mitochondrial (DHODH) 32.7
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 32.7
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 32.2
 LDTP09388  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) 32.0
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 32.0
 LDTP05006  Ras-related protein Rab-1A (RAB1A) 32.0
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 31.8
 LDTP13675  COP9 signalosome complex subunit 3 (COPS3) 31.1
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 31.1
 LDTP12867  Very-long-chain enoyl-CoA reductase (TECR) 31.1
 LDTP01560  NADH dehydrogenase 1 subunit C2 (NDUFC2) 30.9
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 30.9
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 30.7
 LDTP03662  Long-chain-fatty-acid--CoA ligase 1 (ACSL1) 30.3
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) 30.3
 LDTP07756  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) 30.3
 LDTP05622  Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT2) 29.9
 LDTP04353  Protoporphyrinogen oxidase (PPOX) 29.7
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 29.4
 LDTP11259  Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) 29.4
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 29.4
 LDTP10432  ATP synthase membrane subunit K, mitochondrial (ATP5MK) 29.2
 LDTP00416  CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) 29.2
 LDTP08532  Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) 29.2
 LDTP00982  Long-chain-fatty-acid--CoA ligase 4 (ACSL4) 29.2
 LDTP00492  Ras-related protein Rab-7L1 (RAB29) 29.2
 LDTP10887  Synaptic vesicle membrane protein VAT-1 homolog (VAT1) 29.2
 LDTP02367  Cytochrome c oxidase subunit 6C (COX6C) 28.8
 LDTP00464  Glutathione S-transferase 3, mitochondrial (MGST3) 28.8
 LDTP06371  GTP-binding protein Rheb (RHEB) 28.6
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 28.6
 LDTP08799  Lysophosphatidylserine lipase ABHD12 (ABHD12) 28.6
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 28.4
 LDTP01634  Fatty acid CoA ligase Acsl3 (ACSL3) 28.4
 LDTP00496  Long-chain fatty acid transport protein 2 (SLC27A2) 28.4
 LDTP08790  Mitochondrial cardiolipin hydrolase (PLD6) 28.4
 LDTP13131  7-dehydrocholesterol reductase (DHCR7) 28.2
 LDTP09814  Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) 28.2
 LDTP15155  Thiol S-methyltransferase TMT1B (TMT1B) 28.2
 LDTP11867  UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) 28.2
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 28.1
 LDTP09495  Probable glutathione peroxidase 8 (GPX8) 28.1
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 27.9
 LDTP05905  Acid ceramidase (ASAH1) 27.7
 LDTP03394  Ceramide synthase 1 (CERS1) 27.7
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 27.5
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 27.3
 LDTP11723  Cytosolic 5'-nucleotidase 3A (NT5C3A) 26.9
 LDTP06511  Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) 26.9
 LDTP14427  Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) 26.7
 LDTP09063  Estradiol 17-beta-dehydrogenase 11 (HSD17B11) 26.5
 LDTP03769  Sterol O-acyltransferase 1 (SOAT1) 26.4
 LDTP03150  Methylmalonyl-CoA mutase, mitochondrial (MMUT) 26.2
 LDTP09285  Atypical kinase COQ8A, mitochondrial (COQ8A) 25.8
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 25.8
 LDTP04646  Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) 25.8
 LDTP00344  Stearoyl-CoA desaturase (SCD) 25.8
 LDTP11012  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1) 25.5
 LDTP05638  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4) 25.5
 LDTP03842  Squalene synthase (FDFT1) 25.5
 LDTP14264  Choline/ethanolaminephosphotransferase 1 (CEPT1) 25.1
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 25.1
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 25.1
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 24.9
 LDTP02757  Cytochrome b-c1 complex subunit 7 (UQCRB) 24.9
 LDTP00577  Dihydroxyacetone phosphate acyltransferase (GNPAT) 24.8
 LDTP08598  NAD-dependent protein deacetylase sirtuin-2 (SIRT2) 24.8
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 24.6
 LDTP06721  GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) 24.6
 LDTP00400  Torsin-1B (TOR1B) 24.6
 LDTP01699  Acyl-CoA 6-desaturase (FADS2) 24.4
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 24.4
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 24.4
 LDTP19745  ADP-ribosylation factor-like protein 10 (ARL10) 24.3
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 24.1
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 23.8
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 23.6
 LDTP11733  Ras-related protein Rab-1B (RAB1B) 23.6
 LDTP00186  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) 23.4
 LDTP00589  Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) 23.4
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 23.4
 LDTP06307  Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) 23.3
 LDTP12180  Retinol dehydrogenase 14 (RDH14) 23.1
 LDTP06455  Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL) 23.1
 LDTP13317  NADH dehydrogenase 1 alpha subcomplex subunit 12 (NDUFA12) 22.9
 LDTP04889  Signal peptidase complex subunit 3 (SPCS3) 22.9
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 22.9
Transporter and channel
Click to Show/Hide to Show 132 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 99.7
 LDTP01180  Programmed cell death protein 6 (PDCD6) 99.7
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 99.7
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 95.0
 LDTP12979  Transmembrane protein 14C (TMEM14C) 93.7
 LDTP11250  MICOS complex subunit MIC26 (APOO) 90.5
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 88.0
 LDTP16813  Tetraspanin-3 (TSPAN3) 88.0
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 85.0
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 83.9
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 76.1
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 74.0
 LDTP10065  Transmembrane protein 230 (TMEM230) 72.0
 LDTP08881  Transmembrane protein 199 (TMEM199) 69.1
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 68.6
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 67.6
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 64.9
 LDTP08981  Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) 64.4
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 64.0
 LDTP01804  ATP synthase subunit a (MT-ATP6) 57.3
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 57.3
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 56.1
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 55.7
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 54.9
 LDTP15948  Transmembrane protein 126A (TMEM126A) 54.9
 LDTP05900  Metaxin-1 (MTX1) 53.1
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 52.0
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 50.6
 LDTP08279  Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) 48.8
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 48.8
 LDTP12738  Ceroid-lipofuscinosis neuronal protein 6 (CLN6) 48.2
 LDTP07667  Transmembrane protein 205 (TMEM205) 48.2
 LDTP11634  Derlin-2 (DERL2) 47.2
 LDTP07531  Sideroflexin-4 (SFXN4) 47.2
 LDTP10731  Sodium-coupled neutral amino acid symporter 2 (SLC38A2) 47.2
 LDTP07058  Transmembrane protein 201 (TMEM201) 46.9
 LDTP12958  ER membrane protein complex subunit 3 (EMC3) 46.2
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 46.2
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 46.2
 LDTP07467  Rhomboid domain-containing protein 2 (RHBDD2) 45.3
 LDTP11615  Protein tweety homolog 3 (TTYH3) 44.9
 LDTP01454  SUN domain-containing protein 1 (SUN1) 44.0
 LDTP00590  Protein RER1 (RER1) 43.4
 LDTP04663  Bax inhibitor 1 (TMBIM6) 42.2
 LDTP00451  Secretory carrier-associated membrane protein 3 (SCAMP3) 42.2
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 41.9
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 41.4
 LDTP09788  Sorting nexin-19 (SNX19) 41.1
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 40.8
 LDTP00872  Peroxisomal membrane protein PMP34 (SLC25A17) 40.8
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 39.1
 LDTP07236  Protein GPR107 (GPR107) 38.9
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 37.8
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 37.5
 LDTP06633  Reticulon-1 (RTN1) 37.5
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 36.3
 LDTP09294  Proton-coupled zinc antiporter SLC30A5 (SLC30A5) 35.3
 LDTP03869  Protein Mpv17 (MPV17) 35.0
 LDTP13599  Calcium load-activated calcium channel (TMCO1) 34.3
 LDTP11291  Transmembrane emp24 domain-containing protein 9 (TMED9) 33.8
 LDTP11732  Magnesium transporter protein 1 (MAGT1) 33.6
 LDTP15967  Tetraspanin-10 (TSPAN10) 33.1
 LDTP06855  Anoctamin-6 (ANO6) 32.7
 LDTP11281  Voltage-gated monoatomic cation channel TMEM109 (TMEM109) 32.7
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 32.4
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 32.0
 LDTP01748  Mitochondrial import receptor subunit TOM40 homolog (TOMM40) 32.0
 LDTP04787  Transmembrane protein 33 (TMEM33) 32.0
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 31.8
 LDTP11213  Nucleoporin NDC1 (NDC1) 31.6
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 31.3
 LDTP11229  Transmembrane protein 70, mitochondrial (TMEM70) 31.1
 LDTP00405  Etoposide-induced protein 2.4 homolog (EI24) 30.5
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 30.5
 LDTP09204  Nucleoporin NUP35 (NUP35) 30.3
 LDTP01352  PRA1 family protein 3 (ARL6IP5) 30.3
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 29.9
 LDTP10398  Receptor expression-enhancing protein 6 (REEP6) 29.9
 LDTP11844  Protein spinster homolog 1 (SPNS1) 29.7
 LDTP12090  Sideroflexin-1 (SFXN1) 29.7
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 29.4
 LDTP06994  ER membrane protein complex subunit 4 (EMC4) 29.0
 LDTP11406  Transmembrane protein 59 (TMEM59) 28.6
 LDTP12078  Mitochondrial glutamate carrier 1 (SLC25A22) 28.2
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 27.7
 LDTP01631  Mitochondrial pyruvate carrier 2 (MPC2) 27.7
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 27.7
 LDTP13256  SUN domain-containing protein 2 (SUN2) 27.7
 LDTP09789  Transmembrane 9 superfamily member 4 (TM9SF4) 27.7
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 27.3
 LDTP09028  Mitoguardin 1 (MIGA1) 27.3
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 26.9
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 26.5
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 26.5
 LDTP05384  Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) 26.5
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 26.5
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 26.5
 LDTP13320  Prenylated Rab acceptor protein 1 (RABAC1) 26.4
 LDTP10073  Protein RFT1 homolog (RFT1) 26.0
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 25.8
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 25.6
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 25.6
 LDTP10754  Pannexin-1 (PANX1) 25.6
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 25.6
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 25.5
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 25.5
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 25.3
 LDTP11609  Endoplasmic reticulum junction formation protein lunapark (LNPK) 25.3
 LDTP01060  PRA1 family protein 2 (PRAF2) 25.3
 LDTP00592  Surfeit locus protein 4 (SURF4) 25.3
 LDTP10621  Sideroflexin-2 (SFXN2) 25.1
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 24.9
 LDTP10148  Store-operated calcium entry-associated regulatory factor (SARAF) 24.9
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 24.8
 LDTP12383  Protein GPR108 (GPR108) 24.6
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 24.4
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 24.3
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 24.3
 LDTP04932  Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) 24.1
 LDTP03952  Reduced folate transporter (SLC19A1) 23.6
 LDTP04723  ATP synthase subunit f, mitochondrial (ATP5MF) 23.4
 LDTP00657  Nucleoporin NUP42 (NUP42) 23.3
 LDTP03717  Prohibitin 1 (PHB1) 23.3
 LDTP04237  Protein ERGIC-53 (LMAN1) 23.3
 LDTP13969  Transmembrane emp24 domain-containing protein 7 (TMED7) 23.3
 LDTP10804  Chloride channel CLIC-like protein 1 (CLCC1) 23.1
 LDTP11826  Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) 23.1
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 23.1
 LDTP06198  Major facilitator superfamily domain-containing protein 10 (MFSD10) 22.9
 LDTP03405  Calnexin (CANX) 22.8
 LDTP09515  Importin-4 (IPO4) 22.8
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 31.1
Immunoglobulin
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03772  Basigin (BSG) 31.1
Other
Click to Show/Hide to Show 108 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 99.7
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 99.7
 LDTP18883  Protein CEBPZOS (CEBPZOS) 99.7
 LDTP10056  Protein FAM162A (FAM162A) 99.7
 LDTP12412  Reticulon-4 (RTN4) 99.7
 LDTP14458  Tetraspanin-6 (TSPAN6) 99.7
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 90.5
 LDTP01167  Reticulon-2 (RTN2) 86.8
 LDTP01522  Reticulon-3 (RTN3) 86.8
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 85.6
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 81.6
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 74.5
 LDTP05160  Nucleobindin-2 (NUCB2) 69.1
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 67.6
 LDTP05375  Nucleobindin-1 (NUCB1) 65.3
 LDTP19963  TraB domain-containing protein (TRABD) 64.9
 LDTP16980  Small integral membrane protein 11 (SMIM11) 62.7
 LDTP00397  Golgi SNAP receptor complex member 2 (GOSR2) 61.4
 LDTP04557  Arfaptin-2 (ARFIP2) 61.0
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 61.0
 LDTP08224  Protein LYRIC (MTDH) 60.5
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 59.3
 LDTP15095  Receptor expression-enhancing protein 3 (REEP3) 58.9
 LDTP14939  Membralin (TMEM259) 58.5
 LDTP13086  Syntaxin-18 (STX18) 54.9
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 54.9
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 53.1
 LDTP16080  Protein FAM114A2 (FAM114A2) 52.3
 LDTP11113  Receptor expression-enhancing protein 2 (REEP2) 52.3
 LDTP08793  Armadillo repeat-containing protein 10 (ARMC10) 52.0
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 52.0
 LDTP09773  Protein FAM3C (FAM3C) 51.3
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 50.9
 LDTP10442  Thioredoxin domain-containing protein 15 (TXNDC15) 50.9
 LDTP13797  HIG1 domain family member 1A, mitochondrial (HIGD1A) 48.5
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 47.8
 LDTP04558  Arfaptin-1 (ARFIP1) 46.5
 LDTP18569  PRELI domain containing protein 3B (PRELID3B) 45.9
 LDTP01494  Protein YIF1A (YIF1A) 45.6
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 42.2
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 41.6
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 41.6
 LDTP16006  Optic atrophy 3 protein (OPA3) 41.4
 LDTP13626  Ubiquilin-1 (UBQLN1) 41.1
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 40.5
 LDTP16078  Heme-binding protein 1 (HEBP1) 39.9
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 39.1
 LDTP01163  Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) 38.6
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 37.3
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 37.0
 LDTP05868  Protein unc-119 homolog A (UNC119) 36.8
 LDTP15887  Lipase maturation factor 2 (LMF2) 36.0
 LDTP14716  ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) 35.8
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 35.0
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 34.8
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 34.8
 LDTP12025  UPF0488 protein C8orf33 (C8orf33) 34.8
 LDTP05054  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (GNG5) 34.3
 LDTP19472  Protein NCBP2AS2 (NCBP2AS2) 33.8
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 33.4
 LDTP10046  Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) 33.4
 LDTP10924  Prohibitin-2 (PHB2) 33.4
 LDTP00729  Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) 33.1
 LDTP15240  LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) 33.1
 LDTP09644  m-AAA protease-interacting protein 1, mitochondrial (MAIP1) 32.2
 LDTP13779  60S ribosome subunit biogenesis protein NIP7 homolog (NIP7) 31.8
 LDTP04356  Emerin (EMD) 31.6
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 31.6
 LDTP06430  Cdc42-interacting protein 4 (TRIP10) 30.7
 LDTP14164  Immediate early response 3-interacting protein 1 (IER3IP1) 30.3
 LDTP01075  Protein CutA (CUTA) 30.1
 LDTP15398  Protein FAM177A1 (FAM177A1) 30.1
 LDTP18132  Protein FAM136A (FAM136A) 29.9
 LDTP05530  Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) 29.2
 LDTP08300  Reticulophagy regulator 3 (RETREG3) 28.8
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 28.1
 LDTP03466  Transcription initiation factor IIE subunit beta (GTF2E2) 28.1
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 27.9
 LDTP08796  Protein SYS1 homolog (SYS1) 27.9
 LDTP18272  Transmembrane protein 209 (TMEM209) 27.7
 LDTP06808  Vacuolar ATPase assembly integral membrane protein VMA21 (VMA21) 27.7
 LDTP09108  Mitoregulin (MTLN) 27.3
 LDTP08761  NADH dehydrogenase 1 alpha subcomplex assembly factor 2 (NDUFAF2) 27.3
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 27.1
 LDTP11210  Transmembrane protein 43 (TMEM43) 26.9
 LDTP13954  Complex I intermediate-associated protein 30, mitochondrial (NDUFAF1) 26.5
 LDTP09324  Ganglioside-induced differentiation-associated protein 1 (GDAP1) 26.5
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 26.2
 LDTP19010  Tumor protein p53-inducible protein 11 (TP53I11) 26.2
 LDTP08606  Nurim (NRM) 26.0
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 25.6
 LDTP11774  Oxysterol-binding protein-related protein 2 (OSBPL2) 25.1
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 24.9
 LDTP14491  Mannose-P-dolichol utilization defect 1 protein (MPDU1) 24.3
 LDTP10207  Mitochondrial import inner membrane translocase subunit TIM14 (DNAJC19) 24.1
 LDTP07668  Ubiquinol-cytochrome-c reductase complex assembly factor 3 (UQCC3) 24.1
 LDTP12746  Gem-associated protein 8 (GEMIN8) 23.9
 LDTP01206  Vesicle-trafficking protein SEC22b (SEC22B) 23.9
 LDTP00986  Syntaxin-10 (STX10) 23.8
 LDTP17652  Uncharacterized protein KIAA2013 (KIAA2013) 23.8
 LDTP13967  Transmembrane emp24 domain-containing protein 5 (TMED5) 23.4
 LDTP20361  Coiled-coil domain-containing protein 127 (CCDC127) 23.3
 LDTP13863  DnaJ homolog subfamily C member 16 (DNAJC16) 23.3
 LDTP17659  ELMO domain-containing protein 2 (ELMOD2) 23.3
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 23.1
 LDTP12982  Mitochondrial import receptor subunit TOM7 homolog (TOMM7) 23.1
 LDTP11140  Peroxiredoxin-like 2A (PRXL2A) 23.1
 LDTP11143  Centromere protein K (CENPK) 22.8

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587