Details of the Probe

General Information of Probe

Probe ID
LDPC0345
Probe Name
C094
Synonyms
Z4282859879
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 363.34
Lipid-water partition coefficient (xlogp) 3.2
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C17H16F3N5O
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[[4-[3-(trifluoromethyl)diazirin-3-yl]phenyl]methyl]propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NCC2=CC=C(C=C2)C3(N=N3)C(F)(F)F
InChI
InChI=1S/C17H16F3N5O/c1-2-3-9-15(22-23-15)10-8-14(26)21-11-12-4-6-13(7-5-12)16(24-25-16)17(18,19)20/h1,4-7H,3,8-11H2,(H,21,26)
InChIKey
RSRQJMWPPIUHSI-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

166 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1) LDTP11012 25.46  LDD1785 
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) LDTP06657 37.01  LDD1785 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 37.79  LDD1785 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 29.45  LDD1785 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 28.25  LDD1785 
Acid ceramidase (ASAH1) LDTP05905 27.67  LDD1785 
Acyl-CoA 6-desaturase (FADS2) LDTP01699 24.42  LDD1785 
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) LDTP09814 28.25  LDD1785 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 45.57  LDD1785 
ADP-dependent glucokinase (ADPGK) LDTP11127 99.73  LDD1785 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 24.25  LDD1785 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 47.50  LDD1785 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 23.43  LDD1785 
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT2) LDTP05622 29.86  LDD1785 
Atlastin-2 (ATL2) LDTP09251 36.76  LDD1785 
ATP synthase membrane subunit K, mitochondrial (ATP5MK) LDTP10432 29.24  LDD1785 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 24.93  LDD1785 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 24.59  LDD1785 
ATPase GET3 (GET3) LDTP00836 58.89  LDD1785 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 25.81  LDD1785 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 64.00  LDD1785 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 43.41  LDD1785 
Catechol O-methyltransferase (COMT) LDTP03145 52.71  LDD1785 
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) LDTP00416 29.24  LDD1785 
Ceramide synthase 1 (CERS1) LDTP03394 27.67  LDD1785 
Ceramide synthase 2 (CERS2) LDTP10329 66.72  LDD1785 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 36.50  LDD1785 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 25.11  LDD1785 
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4) LDTP05638 25.46  LDD1785 
COP9 signalosome complex subunit 3 (COPS3) LDTP13675 31.12  LDD1785 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 25.81  LDD1785 
Cytochrome b-c1 complex subunit 7 (UQCRB) LDTP02757 24.93  LDD1785 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 95.01  LDD1785 
Cytochrome b5 type B (CYB5B) LDTP00697 89.88  LDD1785 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 32.90  LDD1785 
Cytochrome c oxidase subunit 6C (COX6C) LDTP02367 28.84  LDD1785 
Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) LDTP14427 26.72  LDD1785 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 42.52  LDD1785 
Cytosolic 5'-nucleotidase 3A (NT5C3A) LDTP11723 26.91  LDD1785 
DCN1-like protein 5 (DCUN1D5) LDTP11199 34.54  LDD1785 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 37.01  LDD1785 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 24.42  LDD1785 
Delta(24)-sterol reductase (DHCR24) LDTP06375 24.42  LDD1785 
Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) LDTP04646 25.81  LDD1785 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 40.79  LDD1785 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 62.68  LDD1785 
Dihydroorotate dehydrogenase (quinone), mitochondrial (DHODH) LDTP05337 32.67  LDD1785 
Dihydroxyacetone phosphate acyltransferase (GNPAT) LDTP00577 24.76  LDD1785 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 29.45  LDD1785 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 52.35  LDD1785 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) LDTP09388 32.00  LDD1785 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 79.89  LDD1785 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 90.51  LDD1785 
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) LDTP06511 26.91  LDD1785 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 32.22  LDD1785 
Epimerase family protein SDR39U1 (SDR39U1) LDTP16070 43.11  LDD1785 
Epoxide hydrolase 1 (EPHX1) LDTP02175 28.44  LDD1785 
Estradiol 17-beta-dehydrogenase 11 (HSD17B11) LDTP09063 26.54  LDD1785 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 28.44  LDD1785 
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) LDTP06721 24.59  LDD1785 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 28.84  LDD1785 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 41.64  LDD1785 
Glycerol-3-phosphate acyltransferase 4 (GPAT4) LDTP08232 33.36  LDD1785 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 52.71  LDD1785 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 57.28  LDD1785 
GTP-binding protein Rheb (RHEB) LDTP06371 28.64  LDD1785 
GTP-binding protein SAR1a (SAR1A) LDTP12470 30.70  LDD1785 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 46.85  LDD1785 
Heme A synthase COX15 (COX15) LDTP07931 45.57  LDD1785 
Heme oxygenase 1 (HMOX1) LDTP02359 99.73  LDD1785 
Heme oxygenase 2 (HMOX2) LDTP03540 80.45  LDD1785 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 27.47  LDD1785 
Hexokinase-2 (HK2) LDTP04531 36.76  LDD1785 
Holocytochrome c-type synthase (HCCS) LDTP04581 41.93  LDD1785 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 23.75  LDD1785 
Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) LDTP08532 29.24  LDD1785 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 28.64  LDD1785 
Lathosterol oxidase (SC5D) LDTP01329 46.21  LDD1785 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 78.79  LDD1785 
Long-chain fatty acid transport protein 2 (SLC27A2) LDTP00496 28.44  LDD1785 
Long-chain-fatty-acid--CoA ligase 1 (ACSL1) LDTP03662 30.27  LDD1785 
Long-chain-fatty-acid--CoA ligase 4 (ACSL4) LDTP00982 29.24  LDD1785 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 32.00  LDD1785 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 28.64  LDD1785 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 48.84  LDD1785 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 29.45  LDD1785 
Methylmalonyl-CoA mutase, mitochondrial (MMUT) LDTP03150 26.17  LDD1785 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 69.55  LDD1785 
Microsomal glutathione S-transferase 2 (MGST2) LDTP10966 43.11  LDD1785 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 28.44  LDD1785 
Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1) LDTP10038 62.25  LDD1785 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 39.95  LDD1785 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 27.86  LDD1785 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 24.76  LDD1785 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 93.70  LDD1785 
NADH dehydrogenase 1 alpha subcomplex subunit 12 (NDUFA12) LDTP13317 22.94  LDD1785 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 62.25  LDD1785 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 25.11  LDD1785 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 52.35  LDD1785 
NADH dehydrogenase 1 subunit C2 (NDUFC2) LDTP01560 30.91  LDD1785 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 91.14  LDD1785 
NADH-ubiquinone oxidoreductase chain 5 (MT-ND5) LDTP01986 43.11  LDD1785 
NADPH--cytochrome P450 reductase (POR) LDTP02848 28.05  LDD1785 
Neutral cholesterol ester hydrolase 1 (NCEH1) LDTP07591 34.06  LDD1785 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 23.59  LDD1785 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 41.93  LDD1785 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 34.78  LDD1785 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 23.26  LDD1785 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 23.43  LDD1785 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 48.17  LDD1785 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 31.12  LDD1785 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 44.32  LDD1785 
Phosphatidylserine synthase 2 (PTDSS2) LDTP11284 41.64  LDD1785 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 27.28  LDD1785 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 59.30  LDD1785 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 45.57  LDD1785 
Presenilin-associated rhomboid-like protein, mitochondrial (PARL) LDTP11852 39.67  LDD1785 
Probable glutathione peroxidase 8 (GPX8) LDTP09495 28.05  LDD1785 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 60.55  LDD1785 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 24.08  LDD1785 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 40.79  LDD1785 
Protein O-mannose kinase (POMK) LDTP11957 55.72  LDD1785 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 25.11  LDD1785 
Protein-L-histidine N-pros-methyltransferase (METTL9) LDTP15962 44.63  LDD1785 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 79.89  LDD1785 
Protoporphyrinogen oxidase (PPOX) LDTP04353 29.65  LDD1785 
Ras-related protein Rab-1A (RAB1A) LDTP05006 32.00  LDD1785 
Ras-related protein Rab-1B (RAB1B) LDTP11733 23.59  LDD1785 
Ras-related protein Rab-24 (RAB24) LDTP10020 41.07  LDD1785 
Ras-related protein Rab-7L1 (RAB29) LDTP00492 29.24  LDD1785 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 38.59  LDD1785 
Retinol dehydrogenase 13 (RDH13) LDTP09061 30.91  LDD1785 
Retinol dehydrogenase 14 (RDH14) LDTP12180 23.10  LDD1785 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 23.43  LDD1785 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 32.67  LDD1785 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 34.78  LDD1785 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 74.54  LDD1785 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 99.73  LDD1785 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 56.49  LDD1785 
Signal peptidase complex subunit 3 (SPCS3) LDTP04889 22.94  LDD1785 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 56.89  LDD1785 
Squalene monooxygenase (SQLE) LDTP06142 61.39  LDD1785 
Squalene synthase (FDFT1) LDTP03842 25.46  LDD1785 
Stearoyl-CoA desaturase (SCD) LDTP00344 25.81  LDD1785 
Sterol carrier protein 2 (SCP2) LDTP03163 33.82  LDD1785 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 26.35  LDD1785 
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL) LDTP06455 23.10  LDD1785 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 22.94  LDD1785 
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) LDTP14278 33.82  LDD1785 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 29.24  LDD1785 
Thiol S-methyltransferase TMT1B (TMT1B) LDTP15155 28.25  LDD1785 
Thioredoxin-like protein 1 (TXNL1) LDTP00758 39.12  LDD1785 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 38.32  LDD1785 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 31.78  LDD1785 
Torsin-1B (TOR1B) LDTP00400 24.59  LDD1785 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 30.27  LDD1785 
Ubiquitin-associated domain-containing protein 2 (UBAC2) LDTP09060 41.64  LDD1785 
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) LDTP11867 28.25  LDD1785 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 40.79  LDD1785 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) LDTP07756 30.27  LDD1785 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 37.79  LDD1785 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 47.18  LDD1785 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 31.12  LDD1785 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 37.79  LDD1785 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 79.34  LDD1785 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 41.64  LDD1785 
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⏷ Show the Full List of 166 Enzyme
132 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 25.81  LDD1785 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 24.42  LDD1785 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 26.54  LDD1785 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 25.63  LDD1785 
Anoctamin-6 (ANO6) LDTP06855 32.67  LDD1785 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 39.12  LDD1785 
ATP synthase subunit a (MT-ATP6) LDTP01804 57.28  LDD1785 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 27.67  LDD1785 
ATP synthase subunit f, mitochondrial (ATP5MF) LDTP04723 23.43  LDD1785 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 88.03  LDD1785 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 37.79  LDD1785 
Bax inhibitor 1 (TMBIM6) LDTP04663 42.22  LDD1785 
Calcium load-activated calcium channel (TMCO1) LDTP13599 34.30  LDD1785 
Calnexin (CANX) LDTP03405 22.78  LDD1785 
Ceroid-lipofuscinosis neuronal protein 6 (CLN6) LDTP12738 48.17  LDD1785 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 23.10  LDD1785 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 64.45  LDD1785 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 68.59  LDD1785 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 25.28  LDD1785 
Derlin-2 (DERL2) LDTP11634 47.18  LDD1785 
Endoplasmic reticulum junction formation protein lunapark (LNPK) LDTP11609 25.28  LDD1785 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 64.89  LDD1785 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 95.01  LDD1785 
ER membrane protein complex subunit 3 (EMC3) LDTP12958 46.21  LDD1785 
ER membrane protein complex subunit 4 (EMC4) LDTP06994 29.04  LDD1785 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 85.04  LDD1785 
Etoposide-induced protein 2.4 homolog (EI24) LDTP00405 30.48  LDD1785 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 25.46  LDD1785 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 46.21  LDD1785 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 26.54  LDD1785 
Importin-4 (IPO4) LDTP09515 22.78  LDD1785 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 29.86  LDD1785 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 27.28  LDD1785 
Lysosome membrane protein 2 (SCARB2) LDTP06034 25.63  LDD1785 
Magnesium transporter protein 1 (MAGT1) LDTP11732 33.59  LDD1785 
Major facilitator superfamily domain-containing protein 10 (MFSD10) LDTP06198 22.94  LDD1785 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 30.48  LDD1785 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 40.79  LDD1785 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 41.36  LDD1785 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 51.98  LDD1785 
Metaxin-1 (MTX1) LDTP05900 53.08  LDD1785 
MICOS complex subunit MIC26 (APOO) LDTP11250 90.51  LDD1785 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 32.00  LDD1785 
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) LDTP05384 26.54  LDD1785 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 31.34  LDD1785 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 50.56  LDD1785 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 26.54  LDD1785 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 48.84  LDD1785 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 54.95  LDD1785 
Mitochondrial glutamate carrier 1 (SLC25A22) LDTP12078 28.25  LDD1785 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 46.21  LDD1785 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1785 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 55.72  LDD1785 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 32.00  LDD1785 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 41.93  LDD1785 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 31.78  LDD1785 
Mitochondrial pyruvate carrier 2 (MPC2) LDTP01631 27.67  LDD1785 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 24.25  LDD1785 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 27.67  LDD1785 
Mitoguardin 1 (MIGA1) LDTP09028 27.28  LDD1785 
Mpv17-like protein 2 (MPV17L2) LDTP14952 74.03  LDD1785 
Nucleoporin NDC1 (NDC1) LDTP11213 31.56  LDD1785 
Nucleoporin NUP35 (NUP35) LDTP09204 30.27  LDD1785 
Nucleoporin NUP42 (NUP42) LDTP00657 23.26  LDD1785 
Pannexin-1 (PANX1) LDTP10754 25.63  LDD1785 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 37.53  LDD1785 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 24.25  LDD1785 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 26.54  LDD1785 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 29.45  LDD1785 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 40.79  LDD1785 
PRA1 family protein 2 (PRAF2) LDTP01060 25.28  LDD1785 
PRA1 family protein 3 (ARL6IP5) LDTP01352 30.27  LDD1785 
Prenylated Rab acceptor protein 1 (RABAC1) LDTP13320 26.35  LDD1785 
Programmed cell death protein 6 (PDCD6) LDTP01180 99.73  LDD1785 
Prohibitin 1 (PHB1) LDTP03717 23.26  LDD1785 
Protein ERGIC-53 (LMAN1) LDTP04237 23.26  LDD1785 
Protein GPR107 (GPR107) LDTP07236 38.85  LDD1785 
Protein GPR108 (GPR108) LDTP12383 24.59  LDD1785 
Protein Mpv17 (MPV17) LDTP03869 35.02  LDD1785 
Protein RER1 (RER1) LDTP00590 43.41  LDD1785 
Protein RFT1 homolog (RFT1) LDTP10073 25.99  LDD1785 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 24.76  LDD1785 
Protein spinster homolog 1 (SPNS1) LDTP11844 29.65  LDD1785 
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) LDTP04932 24.08  LDD1785 
Protein tweety homolog 3 (TTYH3) LDTP11615 44.94  LDD1785 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 35.26  LDD1785 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 76.11  LDD1785 
Receptor expression-enhancing protein 6 (REEP6) LDTP10398 29.86  LDD1785 
Reduced folate transporter (SLC19A1) LDTP03952 23.59  LDD1785 
Reticulon-1 (RTN1) LDTP06633 37.53  LDD1785 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 45.25  LDD1785 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 24.93  LDD1785 
Secretory carrier-associated membrane protein 3 (SCAMP3) LDTP00451 42.22  LDD1785 
Sideroflexin-1 (SFXN1) LDTP12090 29.65  LDD1785 
Sideroflexin-2 (SFXN2) LDTP10621 25.11  LDD1785 
Sideroflexin-4 (SFXN4) LDTP07531 47.18  LDD1785 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 67.65  LDD1785 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 47.18  LDD1785 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 23.10  LDD1785 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 48.84  LDD1785 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 25.46  LDD1785 
Sorting nexin-19 (SNX19) LDTP09788 41.07  LDD1785 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 26.91  LDD1785 
Store-operated calcium entry-associated regulatory factor (SARAF) LDTP10148 24.93  LDD1785 
SUN domain-containing protein 1 (SUN1) LDTP01454 44.02  LDD1785 
SUN domain-containing protein 2 (SUN2) LDTP13256 27.67  LDD1785 
Surfeit locus protein 4 (SURF4) LDTP00592 25.28  LDD1785 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 99.73  LDD1785 
Tetraspanin-10 (TSPAN10) LDTP15967 33.13  LDD1785 
Tetraspanin-3 (TSPAN3) LDTP16813 88.03  LDD1785 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 36.25  LDD1785 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 57.28  LDD1785 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1785 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 32.45  LDD1785 
Transmembrane 9 superfamily member 4 (TM9SF4) LDTP09789 27.67  LDD1785 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 25.63  LDD1785 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 23.10  LDD1785 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 23.26  LDD1785 
Transmembrane emp24 domain-containing protein 9 (TMED9) LDTP11291 33.82  LDD1785 
Transmembrane protein 126A (TMEM126A) LDTP15948 54.95  LDD1785 
Transmembrane protein 14C (TMEM14C) LDTP12979 93.70  LDD1785 
Transmembrane protein 199 (TMEM199) LDTP08881 69.07  LDD1785 
Transmembrane protein 201 (TMEM201) LDTP07058 46.85  LDD1785 
Transmembrane protein 205 (TMEM205) LDTP07667 48.17  LDD1785 
Transmembrane protein 230 (TMEM230) LDTP10065 72.00  LDD1785 
Transmembrane protein 33 (TMEM33) LDTP04787 32.00  LDD1785 
Transmembrane protein 59 (TMEM59) LDTP11406 28.64  LDD1785 
Transmembrane protein 70, mitochondrial (TMEM70) LDTP11229 31.12  LDD1785 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 64.00  LDD1785 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 83.87  LDD1785 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 56.10  LDD1785 
Voltage-gated monoatomic cation channel TMEM109 (TMEM109) LDTP11281 32.67  LDD1785 
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⏷ Show the Full List of 132 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 31.12  LDD1785 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 31.12  LDD1785 
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108 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
60S ribosome subunit biogenesis protein NIP7 homolog (NIP7) LDTP13779 31.78  LDD1785 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 50.91  LDD1785 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 23.10  LDD1785 
Arfaptin-1 (ARFIP1) LDTP04558 46.53  LDD1785 
Arfaptin-2 (ARFIP2) LDTP04557 60.97  LDD1785 
Armadillo repeat-containing protein 10 (ARMC10) LDTP08793 51.98  LDD1785 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 35.75  LDD1785 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 25.63  LDD1785 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 33.36  LDD1785 
Cdc42-interacting protein 4 (TRIP10) LDTP06430 30.70  LDD1785 
Centromere protein K (CENPK) LDTP11143 22.78  LDD1785 
Coiled-coil domain-containing protein 127 (CCDC127) LDTP20361 23.26  LDD1785 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 28.05  LDD1785 
Complex I intermediate-associated protein 30, mitochondrial (NDUFAF1) LDTP13954 26.54  LDD1785 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 99.73  LDD1785 
DnaJ homolog subfamily C member 16 (DNAJC16) LDTP13863 23.26  LDD1785 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 27.86  LDD1785 
ELMO domain-containing protein 2 (ELMOD2) LDTP17659 23.26  LDD1785 
Emerin (EMD) LDTP04356 31.56  LDD1785 
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) LDTP10046 33.36  LDD1785 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 99.73  LDD1785 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 59.30  LDD1785 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 85.63  LDD1785 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 47.84  LDD1785 
Ganglioside-induced differentiation-associated protein 1 (GDAP1) LDTP09324 26.54  LDD1785 
Gem-associated protein 8 (GEMIN8) LDTP12746 23.92  LDD1785 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 33.13  LDD1785 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 41.64  LDD1785 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 35.02  LDD1785 
Golgi SNAP receptor complex member 2 (GOSR2) LDTP00397 61.39  LDD1785 
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (GNG5) LDTP05054 34.30  LDD1785 
Heme-binding protein 1 (HEBP1) LDTP16078 39.95  LDD1785 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 48.50  LDD1785 
Immediate early response 3-interacting protein 1 (IER3IP1) LDTP14164 30.27  LDD1785 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 29.24  LDD1785 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 41.64  LDD1785 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 37.01  LDD1785 
Lipase maturation factor 2 (LMF2) LDTP15887 36.00  LDD1785 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 33.13  LDD1785 
m-AAA protease-interacting protein 1, mitochondrial (MAIP1) LDTP09644 32.22  LDD1785 
Mannose-P-dolichol utilization defect 1 protein (MPDU1) LDTP14491 24.25  LDD1785 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 39.12  LDD1785 
Membralin (TMEM259) LDTP14939 58.49  LDD1785 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 81.57  LDD1785 
MICOS complex subunit MIC27 (APOOL) LDTP07718 27.10  LDD1785 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 74.54  LDD1785 
Mitochondrial import inner membrane translocase subunit TIM14 (DNAJC19) LDTP10207 24.08  LDD1785 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 60.97  LDD1785 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 90.51  LDD1785 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 23.10  LDD1785 
Mitoregulin (MTLN) LDTP09108 27.28  LDD1785 
NADH dehydrogenase 1 alpha subcomplex assembly factor 2 (NDUFAF2) LDTP08761 27.28  LDD1785 
Nucleobindin-1 (NUCB1) LDTP05375 65.34  LDD1785 
Nucleobindin-2 (NUCB2) LDTP05160 69.07  LDD1785 
Nurim (NRM) LDTP08606 25.99  LDD1785 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 37.27  LDD1785 
Optic atrophy 3 protein (OPA3) LDTP16006 41.36  LDD1785 
Oxysterol-binding protein-related protein 2 (OSBPL2) LDTP11774 25.11  LDD1785 
Peroxiredoxin-like 2A (PRXL2A) LDTP11140 23.10  LDD1785 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 42.22  LDD1785 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 24.93  LDD1785 
PRELI domain containing protein 3B (PRELID3B) LDTP18569 45.89  LDD1785 
Prohibitin-2 (PHB2) LDTP10924 33.36  LDD1785 
Protein CEBPZOS (CEBPZOS) LDTP18883 99.73  LDD1785 
Protein CutA (CUTA) LDTP01075 30.06  LDD1785 
Protein FAM114A2 (FAM114A2) LDTP16080 52.35  LDD1785 
Protein FAM136A (FAM136A) LDTP18132 29.86  LDD1785 
Protein FAM162A (FAM162A) LDTP10056 99.73  LDD1785 
Protein FAM177A1 (FAM177A1) LDTP15398 30.06  LDD1785 
Protein FAM3C (FAM3C) LDTP09773 51.27  LDD1785 
Protein jagunal homolog 1 (JAGN1) LDTP08904 67.65  LDD1785 
Protein LYRIC (MTDH) LDTP08224 60.55  LDD1785 
Protein NCBP2AS2 (NCBP2AS2) LDTP19472 33.82  LDD1785 
Protein SYS1 homolog (SYS1) LDTP08796 27.86  LDD1785 
Protein unc-119 homolog A (UNC119) LDTP05868 36.76  LDD1785 
Protein YIF1A (YIF1A) LDTP01494 45.57  LDD1785 
Receptor expression-enhancing protein 2 (REEP2) LDTP11113 52.35  LDD1785 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 58.89  LDD1785 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 40.50  LDD1785 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 34.78  LDD1785 
Reticulon-2 (RTN2) LDTP01167 86.82  LDD1785 
Reticulon-3 (RTN3) LDTP01522 86.82  LDD1785 
Reticulon-4 (RTN4) LDTP12412 99.73  LDD1785 
Reticulophagy regulator 3 (RETREG3) LDTP08300 28.84  LDD1785 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 51.98  LDD1785 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 34.78  LDD1785 
Small integral membrane protein 11 (SMIM11) LDTP16980 62.68  LDD1785 
Syntaxin-10 (STX10) LDTP00986 23.75  LDD1785 
Syntaxin-18 (STX18) LDTP13086 54.95  LDD1785 
Tetraspanin-6 (TSPAN6) LDTP14458 99.73  LDD1785 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 50.91  LDD1785 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 53.08  LDD1785 
TraB domain-containing protein (TRABD) LDTP19963 64.89  LDD1785 
Transcription initiation factor IIE subunit beta (GTF2E2) LDTP03466 28.05  LDD1785 
Translocon-associated protein subunit delta (SSR4) LDTP04425 26.17  LDD1785 
Transmembrane emp24 domain-containing protein 5 (TMED5) LDTP13967 23.43  LDD1785 
Transmembrane protein 209 (TMEM209) LDTP18272 27.67  LDD1785 
Transmembrane protein 43 (TMEM43) LDTP11210 26.91  LDD1785 
Tumor protein p53-inducible protein 11 (TP53I11) LDTP19010 26.17  LDD1785 
Ubiquilin-1 (UBQLN1) LDTP13626 41.07  LDD1785 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 54.95  LDD1785 
Ubiquinol-cytochrome-c reductase complex assembly factor 3 (UQCC3) LDTP07668 24.08  LDD1785 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 38.59  LDD1785 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 23.75  LDD1785 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 34.78  LDD1785 
Vacuolar ATPase assembly integral membrane protein VMA21 (VMA21) LDTP06808 27.67  LDD1785 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 31.56  LDD1785 
Vesicle-trafficking protein SEC22b (SEC22B) LDTP01206 23.92  LDD1785 
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⏷ Show the Full List of 108 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1785 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587