General Information of Probe

Probe ID
LDPC0075
Probe Name
JN0003
Synonyms
FFF-2; SCHEMBL20419265; CGP201708; 3-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)-1-(4-phenylpiperidin-1-yl)propan-1-one; 2089059-93-6
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 309.4
Lipid-water partition coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C19H23N3O
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-1-(4-phenylpiperidin-1-yl)propan-1-one
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)N2CCC(CC2)C3=CC=CC=C3
InChI
InChI=1S/C19H23N3O/c1-2-3-12-19(20-21-19)13-9-18(23)22-14-10-17(11-15-22)16-7-5-4-6-8-16/h1,4-8,17H,3,9-15H2
InChIKey
GRNLZAHDRUYPME-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

268 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1) LDTP06612 20.00  LDD0469 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 20.00  LDD0469 
26S proteasome regulatory subunit 6A (PSMC3) LDTP02933 5.34  LDD0469 
26S proteasome regulatory subunit 8 (PSMC5) LDTP04963 20.00  LDD0469 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 12.13  LDD0469 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 20.00  LDD0484 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 20.00  LDD0469 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 20.00  LDD0469 
5'-nucleotidase domain-containing protein 2 (NT5DC2) LDTP18414 7.37  LDD0469 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 5.38  LDD0469 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 20.00  LDD0469 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 20.00  LDD0469 
Aconitate hydratase, mitochondrial (ACO2) LDTP10982 20.00  LDD0469 
Actin, alpha skeletal muscle (ACTA1) LDTP05073 5.13  LDD0469 
Actin, aortic smooth muscle (ACTA2) LDTP04999 7.95  LDD0469 
Actin, cytoplasmic 1 (ACTB) LDTP04876 5.35  LDD0469 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 20.00  LDD0469 
Adenosylhomocysteinase (AHCY) LDTP03242 5.12  LDD0469 
Adenylate kinase 2, mitochondrial (AK2) LDTP04636 6.01  LDD0469 
ADP-dependent glucokinase (ADPGK) LDTP11127 20.00  LDD0469 
ADP-ribosylation factor 1 (ARF1) LDTP05192 20.00  LDD0469 
ADP-ribosylation factor 3 (ARF3) LDTP04907 20.00  LDD0469 
ADP-ribosylation factor 4 (ARF4) LDTP02942 20.00  LDD0469 
ADP-ribosylation factor 5 (ARF5) LDTP05193 20.00  LDD0469 
ADP-ribosylation factor-like protein 1 (ARL1) LDTP03900 20.00  LDD0469 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 20.00  LDD0469 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 9.47  LDD0484 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 20.00  LDD0469 
Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) LDTP04253 12.27  LDD0469 
Alpha-galactosidase A (GLA) LDTP02141 18.06  LDD0469 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 20.00  LDD0469 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 20.00  LDD0469 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 14.72  LDD0469 
Aspartate aminotransferase, mitochondrial (GOT2) LDTP01783 5.49  LDD0469 
Aspartate--tRNA ligase, mitochondrial (DARS2) LDTP07581 12.06  LDD0469 
Atlastin-3 (ATL3) LDTP07362 20.00  LDD0469 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 15.57  LDD0469 
ATP-binding cassette sub-family D member 3 (ABCD3) LDTP03424 13.00  LDD0469 
ATP-citrate synthase (ACLY) LDTP04561 5.52  LDD0469 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 17.06  LDD0469 
ATP-dependent RNA helicase A (DHX9) LDTP05550 6.38  LDD0469 
ATP-dependent RNA helicase DDX18 (DDX18) LDTP12688 20.00  LDD0469 
ATP-dependent RNA helicase DHX30 (DHX30) LDTP07946 5.19  LDD0469 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 20.00  LDD0484 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 17.62  LDD0469 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 14.40  LDD0469 
Beta-galactosidase (GLB1) LDTP02837 20.00  LDD0469 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 20.00  LDD0469 
Beta-hexosaminidase subunit beta (HEXB) LDTP02216 14.54  LDD0469 
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2) LDTP02706 20.00  LDD0469 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 20.00  LDD0469 
Bleomycin hydrolase (BLMH) LDTP05992 12.04  LDD0469 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 20.00  LDD0469 
Calcyclin-binding protein (CACYBP) LDTP12163 14.70  LDD0469 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 20.00  LDD0469 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 20.00  LDD0469 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 20.00  LDD0469 
Casein kinase I isoform alpha (CSNK1A1) LDTP04209 20.00  LDD0469 
Catechol O-methyltransferase (COMT) LDTP03145 18.52  LDD0469 
Cathepsin B (CTSB) LDTP02223 12.24  LDD0469 
Cathepsin D (CTSD) LDTP02198 20.00  LDD0469 
Ceramide synthase 2 (CERS2) LDTP10329 20.00  LDD0469 
Citrate synthase, mitochondrial (CS) LDTP01205 5.09  LDD0469 
Complex I assembly factor ACAD9, mitochondrial (ACAD9) LDTP12048 15.43  LDD0469 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 12.45  LDD0469 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 12.02  LDD0469 
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 13.11  LDD0469 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 19.85  LDD0469 
Cytochrome b5 type B (CYB5B) LDTP00697 20.00  LDD0469 
Cytochrome c oxidase subunit 1 (MT-CO1) LDTP01772 20.00  LDD0469 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 19.71  LDD0469 
Cytochrome c1, heme protein, mitochondrial (CYC1) LDTP02283 20.00  LDD0469 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 12.76  LDD0469 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 20.00  LDD0469 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 20.00  LDD0469 
Delta(24)-sterol reductase (DHCR24) LDTP06375 20.00  LDD0469 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 13.09  LDD0469 
Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) LDTP04646 14.20  LDD0469 
Dermcidin (DCD) LDTP05171 20.00  LDD0484 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 14.23  LDD0469 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 20.00  LDD0469 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 12.54  LDD0469 
DNA topoisomerase 2-alpha (TOP2A) LDTP02568 12.54  LDD0469 
DNA topoisomerase 2-beta (TOP2B) LDTP05379 8.63  LDD0469 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 12.06  LDD0469 
DNA-directed RNA polymerase, mitochondrial (POLRMT) LDTP00267 7.60  LDD0469 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 20.00  LDD0469 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 20.00  LDD0469 
Dynamin-1-like protein (DNM1L) LDTP00273 12.23  LDD0469 
Dynamin-2 (DNM2) LDTP04374 12.21  LDD0469 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 16.53  LDD0469 
E3 ubiquitin-protein ligase MARCHF5 (MARCHF5) LDTP12757 20.00  LDD0469 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 5.76  LDD0469 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 16.55  LDD0469 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 12.90  LDD0469 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 20.00  LDD0469 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 20.00  LDD0469 
Enolase-phosphatase E1 (ENOPH1) LDTP13314 20.00  LDD0469 
Enoyl-CoA delta isomerase 1, mitochondrial (ECI1) LDTP03965 20.00  LDD0469 
Epoxide hydrolase 1 (EPHX1) LDTP02175 20.00  LDD0484 
ERO1-like protein alpha (ERO1A) LDTP10386 10.04  LDD0469 
Estradiol 17-beta-dehydrogenase 11 (HSD17B11) LDTP09063 17.98  LDD0469 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 6.46  LDD0469 
Eukaryotic initiation factor 4A-II (EIF4A2) LDTP06089 5.22  LDD0469 
Exonuclease 1 (EXO1) LDTP13751 12.52  LDD0469 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 20.00  LDD0469 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 5.84  LDD0469 
Fatty acid synthase (FASN) LDTP04243 13.93  LDD0469 
Ferrochelatase, mitochondrial (FECH) LDTP03198 20.00  LDD0469 
Fumarate hydratase, mitochondrial (FH) LDTP02235 20.00  LDD0469 
Gamma-glutamyl hydrolase (GGH) LDTP09886 20.00  LDD0469 
Gamma-interferon-inducible lysosomal thiol reductase (IFI30) LDTP02651 20.00  LDD0469 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 12.22  LDD0469 
Glutamate dehydrogenase 1, mitochondrial (GLUD1) LDTP01768 20.00  LDD0469 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 20.00  LDD0469 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 13.63  LDD0469 
Glutathione S-transferase P (GSTP1) LDTP02333 12.07  LDD0469 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 20.00  LDD0469 
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) LDTP04032 20.00  LDD0469 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 12.13  LDD0469 
GTP-binding protein SAR1a (SAR1A) LDTP12470 20.00  LDD0469 
Helicase MOV-10 (MOV10) LDTP12233 20.00  LDD0469 
Heme A synthase COX15 (COX15) LDTP07931 20.00  LDD0469 
Heme oxygenase 1 (HMOX1) LDTP02359 20.00  LDD0484 
Heme oxygenase 2 (HMOX2) LDTP03540 20.00  LDD0469 
Hexokinase-1 (HK1) LDTP02991 12.80  LDD0469 
Hexokinase-2 (HK2) LDTP04531 20.00  LDD0469 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 19.61  LDD0469 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 8.87  LDD0469 
Holocytochrome c-type synthase (HCCS) LDTP04581 16.32  LDD0469 
Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) LDTP07762 13.20  LDD0469 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 20.00  LDD0469 
Insulin-degrading enzyme (IDE) LDTP02743 19.27  LDD0469 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 12.19  LDD0469 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 10.45  LDD0469 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 14.65  LDD0469 
Isoleucine--tRNA ligase, mitochondrial (IARS2) LDTP12588 12.77  LDD0469 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 5.04  LDD0469 
L-xylulose reductase (DCXR) LDTP08082 20.00  LDD0469 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 20.00  LDD0469 
Lanosterol synthase (LSS) LDTP04183 20.00  LDD0484 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 20.00  LDD0469 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 20.00  LDD0469 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 20.00  LDD0469 
Lon protease homolog, mitochondrial (LONP1) LDTP03817 13.43  LDD0469 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 20.00  LDD0469 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 20.00  LDD0469 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 20.00  LDD0469 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 12.59  LDD0469 
Lysosomal acid phosphatase (ACP2) LDTP02539 20.00  LDD0484 
Lysosomal alpha-glucosidase (GAA) LDTP02486 20.00  LDD0469 
Lysosomal alpha-mannosidase (MAN2B1) LDTP00338 20.00  LDD0469 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 15.16  LDD0469 
Lysosomal protective protein (CTSA) LDTP02505 20.00  LDD0469 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 20.00  LDD0469 
Minor histocompatibility antigen H13 (HM13) LDTP09396 20.00  LDD0469 
Mitochondrial 10-formyltetrahydrofolate dehydrogenase (ALDH1L2) LDTP06796 20.00  LDD0469 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 20.00  LDD0469 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 19.97  LDD0469 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 20.00  LDD0469 
Mitogen-activated protein kinase 1 (MAPK1) LDTP03445 20.00  LDD0469 
Mitogen-activated protein kinase 3 (MAPK3) LDTP03387 12.64  LDD0469 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 20.00  LDD0469 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 13.26  LDD0469 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 20.00  LDD0469 
NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial (NDUFA9) LDTP06631 13.71  LDD0469 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 20.00  LDD0469 
NADH dehydrogenase iron-sulfur protein 3, mitochondrial (NDUFS3) LDTP01238 20.00  LDD0469 
NADH dehydrogenase iron-sulfur protein 7, mitochondrial (NDUFS7) LDTP01165 20.00  LDD0469 
NADH-cytochrome b5 reductase 3 (CYB5R3) LDTP01770 20.00  LDD0469 
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (NDUFS1) LDTP03433 12.60  LDD0469 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 19.63  LDD0469 
NADH-ubiquinone oxidoreductase chain 5 (MT-ND5) LDTP01986 20.00  LDD0469 
NADPH--cytochrome P450 reductase (POR) LDTP02848 19.88  LDD0469 
Nardilysin (NRDC) LDTP00886 20.00  LDD0469 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 20.00  LDD0469 
Nucleolar RNA helicase 2 (DDX21) LDTP12469 7.79  LDD0469 
Obg-like ATPase 1 (OLA1) LDTP12610 15.25  LDD0469 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 20.00  LDD0469 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 20.00  LDD0469 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 20.00  LDD0469 
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) LDTP06104 20.00  LDD0469 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 20.00  LDD0469 
Phenylalanine--tRNA ligase alpha subunit (FARSA) LDTP13831 20.00  LDD0469 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 12.00  LDD0469 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 20.00  LDD0469 
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) LDTP06638 20.00  LDD0469 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 20.00  LDD0469 
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (PNPT1) LDTP09390 5.02  LDD0469 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 20.00  LDD0469 
Presequence protease, mitochondrial (PITRM1) LDTP07003 16.52  LDD0469 
Probable ATP-dependent RNA helicase DDX10 (DDX10) LDTP05785 20.00  LDD0469 
Probable ATP-dependent RNA helicase DDX17 (DDX17) LDTP09899 7.71  LDD0469 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 19.43  LDD0469 
Proliferation-associated protein 2G4 (PA2G4) LDTP13750 5.41  LDD0469 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 16.95  LDD0469 
Prolyl endopeptidase-like (PREPL) LDTP06849 13.69  LDD0469 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 20.00  LDD0469 
Prostaglandin reductase 2 (PTGR2) LDTP08979 20.00  LDD0469 
Prostaglandin reductase 3 (PTGR3) LDTP15422 20.00  LDD0469 
Proteasome subunit alpha type-4 (PSMA4) LDTP03333 15.63  LDD0469 
Proteasome subunit alpha type-5 (PSMA5) LDTP03413 14.87  LDD0469 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 12.21  LDD0469 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 20.00  LDD0469 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 20.00  LDD0469 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 17.83  LDD0469 
Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 7.65  LDD0469 
Protein disulfide-isomerase (P4HB) LDTP02188 13.64  LDD0469 
Protein disulfide-isomerase A6 (PDIA6) LDTP06314 6.87  LDD0469 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 20.00  LDD0469 
Protein O-GlcNAcase (OGA) LDTP00988 14.80  LDD0469 
Protein O-mannosyl-transferase TMTC3 (TMTC3) LDTP07868 19.51  LDD0469 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 16.05  LDD0469 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 20.00  LDD0469 
Ras-related protein Rab-1B (RAB1B) LDTP11733 9.65  LDD0469 
Ras-related protein Rab-2A (RAB2A) LDTP04892 20.00  LDD0469 
Ras-related protein Rab-5C (RAB5C) LDTP04398 5.00  LDD0469 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 20.00  LDD0469 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 20.00  LDD0469 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 12.12  LDD0469 
Ribosomal biogenesis protein LAS1L (LAS1L) LDTP14074 17.00  LDD0469 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 14.88  LDD0469 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 20.00  LDD0469 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 20.00  LDD0469 
RuvB-like 1 (RUVBL1) LDTP13816 5.42  LDD0469 
RuvB-like 2 (RUVBL2) LDTP13787 16.25  LDD0469 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 20.00  LDD0469 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 20.00  LDD0469 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 16.69  LDD0469 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 13.40  LDD0469 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 20.00  LDD0469 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 20.00  LDD0469 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 6.94  LDD0469 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 17.75  LDD0469 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 20.00  LDD0469 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 20.00  LDD0469 
Squalene monooxygenase (SQLE) LDTP06142 20.00  LDD0469 
Squalene synthase (FDFT1) LDTP03842 20.00  LDD0469 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 14.79  LDD0469 
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL) LDTP06455 11.61  LDD0469 
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) LDTP03572 13.06  LDD0469 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 17.02  LDD0469 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 12.27  LDD0469 
Thimet oligopeptidase (THOP1) LDTP04542 13.20  LDD0469 
Thiol S-methyltransferase TMT1A (TMT1A) LDTP12056 20.00  LDD0484 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 20.00  LDD0469 
Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 20.00  LDD0469 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 20.00  LDD0469 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 20.00  LDD0469 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 5.04  LDD0469 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 20.00  LDD0469 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 20.00  LDD0469 
tRNA methyltransferase 10 homolog C (TRMT10C) LDTP07937 20.00  LDD0469 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 20.00  LDD0469 
Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) LDTP02935 20.00  LDD0469 
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) LDTP04074 12.44  LDD0469 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 18.42  LDD0484 
UMP-CMP kinase (CMPK1) LDTP03519 20.00  LDD0469 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 20.00  LDD0469 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 16.36  LDD0469 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 19.55  LDD0469 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 20.00  LDD0469 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 20.00  LDD0469 
Vesicle-fusing ATPase (NSF) LDTP04096 12.43  LDD0469 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 20.00  LDD0469 
X-ray repair cross-complementing protein 5 (XRCC5) LDTP02642 13.36  LDD0469 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 20.00  LDD0469 
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP1) LDTP12960 20.00  LDD0469 
------------------------------------------------------------------------------------
⏷ Show the Full List of 268 Enzyme
127 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 14.40  LDD0469 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 20.00  LDD0469 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 16.30  LDD0469 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 14.99  LDD0469 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 15.29  LDD0469 
Annexin A11 (ANXA11) LDTP04393 12.41  LDD0469 
Apoptosis regulator BAX (BAX) LDTP05528 20.00  LDD0469 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 20.00  LDD0469 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 10.29  LDD0469 
ATP synthase subunit d, mitochondrial (ATP5PD) LDTP14509 16.73  LDD0469 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 20.00  LDD0469 
ATP synthase subunit gamma, mitochondrial (ATP5F1C) LDTP03810 20.00  LDD0469 
BOS complex subunit NCLN (NCLN) LDTP10036 20.00  LDD0469 
BRI3-binding protein (BRI3BP) LDTP15648 20.00  LDD0469 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 17.10  LDD0469 
Calnexin (CANX) LDTP03405 20.00  LDD0469 
Copine-3 (CPNE3) LDTP01133 5.31  LDD0469 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 20.00  LDD0469 
Derlin-1 (DERL1) LDTP11245 20.00  LDD0469 
Desmoplakin (DSP) LDTP02815 20.00  LDD0484 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST) LDTP03870 10.14  LDD0469 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 20.00  LDD0469 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 20.00  LDD0469 
EH domain-containing protein 1 (EHD1) LDTP11934 8.45  LDD0469 
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12) LDTP01301 20.00  LDD0469 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 20.00  LDD0469 
Endophilin-B1 (SH3GLB1) LDTP13953 17.20  LDD0469 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 20.00  LDD0469 
Erlin-2 (ERLIN2) LDTP01455 20.00  LDD0469 
Exportin-1 (XPO1) LDTP00501 5.96  LDD0469 
Exportin-5 (XPO5) LDTP12142 12.37  LDD0469 
Filamin-C (FLNC) LDTP06103 20.00  LDD0469 
Flotillin-1 (FLOT1) LDTP01366 20.00  LDD0469 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 20.00  LDD0469 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 10.10  LDD0469 
Hypoxia up-regulated protein 1 (HYOU1) LDTP14066 13.46  LDD0469 
Importin subunit alpha-1 (KPNA2) LDTP04501 17.61  LDD0469 
Importin subunit beta-1 (KPNB1) LDTP06242 7.91  LDD0469 
Importin-11 (IPO11) LDTP13322 6.17  LDD0469 
Importin-4 (IPO4) LDTP09515 5.78  LDD0469 
Importin-5 (IPO5) LDTP00266 12.07  LDD0469 
Importin-7 (IPO7) LDTP01574 12.47  LDD0469 
Importin-9 (IPO9) LDTP10663 14.95  LDD0469 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 16.95  LDD0469 
Kinesin-1 heavy chain (KIF5B) LDTP03664 12.19  LDD0469 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 14.20  LDD0469 
Lysosome membrane protein 2 (SCARB2) LDTP06034 20.00  LDD0469 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 16.21  LDD0469 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 20.00  LDD0469 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 20.00  LDD0469 
Metaxin-1 (MTX1) LDTP05900 20.00  LDD0469 
MICOS complex subunit MIC26 (APOO) LDTP11250 20.00  LDD0469 
MICOS complex subunit MIC60 (IMMT) LDTP06660 20.00  LDD0469 
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) LDTP05384 8.16  LDD0469 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 20.00  LDD0469 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 14.33  LDD0469 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 20.00  LDD0469 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 20.00  LDD0469 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 20.00  LDD0469 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 20.00  LDD0469 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 20.00  LDD0469 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 20.00  LDD0469 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 15.18  LDD0469 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 16.16  LDD0469 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 20.00  LDD0469 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 20.00  LDD0469 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 20.00  LDD0469 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 20.00  LDD0469 
Mpv17-like protein 2 (MPV17L2) LDTP14952 20.00  LDD0484 
Neutral amino acid transporter B(0) (SLC1A5) LDTP06462 11.64  LDD0469 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 20.00  LDD0469 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 20.00  LDD0469 
Nuclear pore complex protein Nup133 (NUP133) LDTP09579 5.64  LDD0469 
Nuclear pore complex protein Nup155 (NUP155) LDTP01295 6.74  LDD0469 
Nuclear pore complex protein Nup205 (NUP205) LDTP09825 20.00  LDD0469 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 20.00  LDD0469 
Nucleoporin NDC1 (NDC1) LDTP11213 20.00  LDD0469 
Nucleoprotein TPR (TPR) LDTP02612 12.86  LDD0469 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 16.96  LDD0469 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 17.09  LDD0469 
Phosphatidylinositol transfer protein beta isoform (PITPNB) LDTP04213 20.00  LDD0469 
Prohibitin 1 (PHB1) LDTP03717 17.26  LDD0469 
Prosaposin (PSAP) LDTP02215 20.00  LDD0469 
Protein GPR107 (GPR107) LDTP07236 20.00  LDD0469 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 20.00  LDD0469 
Protein spinster homolog 1 (SPNS1) LDTP11844 20.00  LDD0469 
Protein tweety homolog 3 (TTYH3) LDTP11615 20.00  LDD0484 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 20.00  LDD0469 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 20.00  LDD0469 
Secretory carrier-associated membrane protein 3 (SCAMP3) LDTP00451 20.00  LDD0469 
Sideroflexin-1 (SFXN1) LDTP12090 16.57  LDD0469 
Sideroflexin-4 (SFXN4) LDTP07531 20.00  LDD0469 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 19.75  LDD0484 
Signal recognition particle subunit SRP68 (SRP68) LDTP13262 20.00  LDD0469 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 15.98  LDD0469 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 20.00  LDD0469 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 20.00  LDD0469 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 20.00  LDD0469 
Sorting nexin-2 (SNX2) LDTP01043 14.17  LDD0469 
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 12.02  LDD0469 
Stomatin-like protein 2, mitochondrial (STOML2) LDTP13416 16.03  LDD0469 
Surfeit locus protein 4 (SURF4) LDTP00592 17.90  LDD0469 
Syntenin-1 (SDCBP) LDTP00310 20.00  LDD0469 
THO complex subunit 1 (THOC1) LDTP10317 20.00  LDD0469 
Transferrin receptor protein 1 (TFRC) LDTP01969 6.26  LDD0469 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 20.00  LDD0469 
Translocation protein SEC63 homolog (SEC63) LDTP13243 20.00  LDD0469 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 20.00  LDD0469 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 20.00  LDD0469 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 20.00  LDD0469 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 15.30  LDD0469 
Transmembrane protein 126A (TMEM126A) LDTP15948 20.00  LDD0469 
Transmembrane protein 160 (TMEM160) LDTP20002 20.00  LDD0469 
Transmembrane protein 33 (TMEM33) LDTP04787 19.23  LDD0469 
Transmembrane protein 65 (TMEM65) LDTP07583 20.00  LDD0469 
Transmembrane protein 87A (TMEM87A) LDTP15481 20.00  LDD0484 
Transportin-1 (TNPO1) LDTP09949 13.29  LDD0469 
Transportin-2 (TNPO2) LDTP00434 13.63  LDD0469 
Transportin-3 (TNPO3) LDTP14133 20.00  LDD0469 
Tricarboxylate transport protein, mitochondrial (SLC25A1) LDTP04553 20.00  LDD0469 
Ubiquilin-4 (UBQLN4) LDTP12533 20.00  LDD0469 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 20.00  LDD0469 
Vesicular integral-membrane protein VIP36 (LMAN2) LDTP05690 17.80  LDD0469 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 20.00  LDD0469 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 20.00  LDD0469 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 20.00  LDD0469 
Zinc transporter 7 (SLC30A7) LDTP09180 20.00  LDD0469 
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⏷ Show the Full List of 127 Transporter and channel
4 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 15.16  LDD0469 
Paraspeckle component 1 (PSPC1) LDTP09694 13.77  LDD0469 
Splicing factor, proline- and glutamine-rich (SFPQ) LDTP03212 14.00  LDD0469 
Y-box-binding protein 1 (YBX1) LDTP05065 20.00  LDD0469 
------------------------------------------------------------------------------------
1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 17.46  LDD0469 
------------------------------------------------------------------------------------
193 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein eta (YWHAH) LDTP05442 5.13  LDD0469 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 13.43  LDD0469 
Actin-related protein 3 (ACTR3) LDTP04902 9.78  LDD0469 
Alpha-2-macroglobulin (A2M) LDTP01814 20.00  LDD0469 
Alpha-actinin-1 (ACTN1) LDTP02631 6.09  LDD0469 
Alpha-actinin-4 (ACTN4) LDTP00843 9.49  LDD0469 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 20.00  LDD0484 
Annexin A7 (ANXA7) LDTP03030 20.00  LDD0469 
AP-3 complex subunit mu-1 (AP3M1) LDTP13908 20.00  LDD0469 
Ataxin-2-like protein (ATXN2L) LDTP09655 20.00  LDD0469 
Beta-actin-like protein 2 (ACTBL2) LDTP14951 7.29  LDD0469 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 20.00  LDD0484 
BTB/POZ domain-containing protein KCTD12 (KCTD12) LDTP15705 15.50  LDD0469 
Calumenin (CALU) LDTP00887 20.00  LDD0469 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 20.00  LDD0469 
Catenin alpha-1 (CTNNA1) LDTP03711 20.00  LDD0469 
CCR4-NOT transcription complex subunit 1 (CNOT1) LDTP00078 8.01  LDD0469 
Centrosomal protein 43 (CEP43) LDTP01652 20.00  LDD0469 
Clustered mitochondria protein homolog (CLUH) LDTP14486 20.00  LDD0469 
Coatomer subunit beta' (COPB2) LDTP03767 12.11  LDD0469 
Coatomer subunit delta (ARCN1) LDTP04181 13.22  LDD0469 
Coatomer subunit epsilon (COPE) LDTP00376 12.63  LDD0469 
Core histone macro-H2A.1 (MACROH2A1) LDTP01195 7.88  LDD0469 
Crk-like protein (CRKL) LDTP04092 20.00  LDD0469 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 13.38  LDD0469 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 9.08  LDD0469 
DNA damage-binding protein 1 (DDB1) LDTP06543 14.23  LDD0469 
DnaJ homolog subfamily A member 1 (DNAJA1) LDTP03606 5.57  LDD0469 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 20.00  LDD0469 
Dynactin subunit 1 (DCTN1) LDTP06082 20.00  LDD0469 
Dynactin subunit 2 (DCTN2) LDTP05922 20.00  LDD0469 
Dynactin subunit 4 (DCTN4) LDTP13402 20.00  LDD0469 
Emerin (EMD) LDTP04356 20.00  LDD0469 
Endoplasmic reticulum resident protein 29 (ERP29) LDTP03509 9.07  LDD0469 
Endoplasmin (HSP90B1) LDTP02734 14.07  LDD0469 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 20.00  LDD0469 
Eukaryotic translation initiation factor 3 subunit E (EIF3E) LDTP04853 13.25  LDD0469 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 12.04  LDD0469 
Eukaryotic translation initiation factor 3 subunit H (EIF3H) LDTP00620 20.00  LDD0469 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 13.43  LDD0469 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 9.73  LDD0469 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 16.98  LDD0469 
Exportin-6 (XPO6) LDTP10749 20.00  LDD0469 
Ezrin (EZR) LDTP02779 5.97  LDD0469 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 17.58  LDD0469 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 16.45  LDD0469 
Far upstream element-binding protein 3 (FUBP3) LDTP10408 14.81  LDD0484 
FAS-associated factor 2 (FAF2) LDTP10185 20.00  LDD0469 
G-rich sequence factor 1 (GRSF1) LDTP05668 12.91  LDD0469 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 20.00  LDD0469 
GPI transamidase component PIG-T (PIGT) LDTP10015 9.77  LDD0469 
HCLS1-associated protein X-1 (HAX1) LDTP00199 20.00  LDD0469 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 12.79  LDD0469 
Heat shock protein beta-1 (HSPB1) LDTP02053 20.00  LDD0469 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 12.42  LDD0469 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 6.10  LDD0469 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 8.90  LDD0469 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 14.23  LDD0469 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 9.66  LDD0469 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 12.66  LDD0469 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 12.77  LDD0469 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 13.23  LDD0469 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 15.02  LDD0469 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 11.37  LDD0469 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 8.23  LDD0469 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 13.28  LDD0469 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 13.19  LDD0469 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 12.86  LDD0469 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 20.00  LDD0469 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 13.71  LDD0469 
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) LDTP02227 11.73  LDD0469 
Histone H1.2 (H1-2) LDTP02845 6.62  LDD0469 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 5.90  LDD0469 
Hornerin (HRNR) LDTP08425 20.00  LDD0469 
Hsc70-interacting protein (ST13) LDTP04367 9.51  LDD0469 
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) LDTP12904 6.31  LDD0469 
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PRKRA) LDTP01259 16.41  LDD0469 
Interleukin enhancer-binding factor 2 (ILF2) LDTP05688 5.78  LDD0469 
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) LDTP05525 12.44  LDD0469 
Kinectin (KTN1) LDTP08238 20.00  LDD0469 
Kinetochore-associated protein 1 (KNTC1) LDTP04382 20.00  LDD0469 
Lamin-B1 (LMNB1) LDTP03065 20.00  LDD0469 
Lamin-B2 (LMNB2) LDTP05400 14.59  LDD0469 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 12.11  LDD0469 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 20.00  LDD0469 
Large proline-rich protein BAG6 (BAG6) LDTP04094 20.00  LDD0469 
Large ribosomal subunit protein mL37 (MRPL37) LDTP15922 20.00  LDD0469 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 20.00  LDD0469 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 12.14  LDD0469 
MAGUK p55 subfamily member 2 (MPP2) LDTP06068 20.00  LDD0469 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 20.00  LDD0469 
Matrin-3 (MATR3) LDTP04027 8.64  LDD0469 
Membralin (TMEM259) LDTP14939 20.00  LDD0469 
Microtubule-associated protein 4 (MAP4) LDTP03404 20.00  LDD0469 
Mitochondrial antiviral-signaling protein (MAVS) LDTP08058 17.16  LDD0469 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 20.00  LDD0469 
Mitochondrial import receptor subunit TOM70 (TOMM70) LDTP01432 13.43  LDD0469 
MMS19 nucleotide excision repair protein homolog (MMS19) LDTP10843 5.32  LDD0469 
Moesin (MSN) LDTP03346 6.39  LDD0469 
Myb-binding protein 1A (MYBBP1A) LDTP11079 9.34  LDD0469 
Myosin regulatory light chain 12B (MYL12B) LDTP00487 5.70  LDD0469 
Negative elongation factor C/D (NELFCD) LDTP08594 20.00  LDD0469 
Neudesin (NENF) LDTP13630 13.75  LDD0469 
Nicastrin (NCSTN) LDTP09787 20.00  LDD0469 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 20.00  LDD0469 
Nucleobindin-1 (NUCB1) LDTP05375 20.00  LDD0469 
Nucleobindin-2 (NUCB2) LDTP05160 20.00  LDD0469 
Nucleolar protein 58 (NOP58) LDTP13925 6.74  LDD0469 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 16.01  LDD0469 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 15.96  LDD0469 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 20.00  LDD0469 
Optic atrophy 3 protein (OPA3) LDTP16006 20.00  LDD0469 
Origin recognition complex subunit 3 (ORC3) LDTP13104 12.73  LDD0469 
Peflin (PEF1) LDTP13167 5.90  LDD0469 
Periodic tryptophan protein 2 homolog (PWP2) LDTP06345 5.58  LDD0469 
Peroxiredoxin-like 2A (PRXL2A) LDTP11140 13.29  LDD0469 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 8.31  LDD0469 
Poly(rC)-binding protein 3 (PCBP3) LDTP04793 16.16  LDD0469 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 20.00  LDD0469 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 7.10  LDD0469 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 12.50  LDD0469 
Polyadenylate-binding protein-interacting protein 1 (PAIP1) LDTP11682 17.37  LDD0469 
Pre-mRNA-processing-splicing factor 8 (PRPF8) LDTP07526 13.72  LDD0469 
Prefoldin subunit 3 (VBP1) LDTP04935 20.00  LDD0469 
Prelamin-A/C (LMNA) LDTP01932 20.00  LDD0469 
Profilin-1 (PFN1) LDTP02218 6.07  LDD0469 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 12.43  LDD0469 
Prohibitin-2 (PHB2) LDTP10924 20.00  LDD0469 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 20.00  LDD0469 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 13.75  LDD0469 
Protein FAM114A2 (FAM114A2) LDTP16080 20.00  LDD0469 
Protein FAM162A (FAM162A) LDTP10056 20.00  LDD0469 
Protein LYRIC (MTDH) LDTP08224 20.00  LDD0469 
Protein NipSnap homolog 1 (NIPSNAP1) LDTP19912 20.00  LDD0469 
Protein PALS2 (PALS2) LDTP16156 14.36  LDD0469 
Protein SET (SET) LDTP05277 20.00  LDD0469 
Protein TASOR (TASOR) LDTP13430 20.00  LDD0469 
Protein TFG (TFG) LDTP09851 20.00  LDD0469 
Protein transport protein Sec23B (SEC23B) LDTP06391 12.52  LDD0469 
Protein unc-119 homolog B (UNC119B) LDTP00105 19.56  LDD0484 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 14.93  LDD0469 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 13.02  LDD0469 
Reticulocalbin-2 (RCN2) LDTP06097 20.00  LDD0469 
Reticulon-3 (RTN3) LDTP01522 18.81  LDD0469 
Reticulon-4 (RTN4) LDTP12412 20.00  LDD0469 
Ribosomal RNA processing protein 1 homolog B (RRP1B) LDTP06182 13.30  LDD0469 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 11.71  LDD0469 
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1) LDTP03495 20.00  LDD0469 
RNA-binding protein 10 (RBM10) LDTP05224 20.00  LDD0469 
RNA-binding protein 14 (RBM14) LDTP10684 20.00  LDD0469 
RNA-binding protein EWS (EWSR1) LDTP05318 20.00  LDD0469 
RNA-binding protein FUS (FUS) LDTP03775 14.55  LDD0469 
RNA-binding protein Musashi homolog 2 (MSI2) LDTP10216 20.00  LDD0469 
Sec1 family domain-containing protein 1 (SCFD1) LDTP09615 16.60  LDD0469 
Serrate RNA effector molecule homolog (SRRT) LDTP11398 12.02  LDD0469 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 20.00  LDD0469 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 13.37  LDD0469 
Small ribosomal subunit protein mS27 (MRPS27) LDTP09793 12.34  LDD0469 
Small ribosomal subunit protein mS39 (PTCD3) LDTP10285 5.57  LDD0469 
Small ribosomal subunit protein mS40 (MRPS18B) LDTP14215 20.00  LDD0469 
Small ribosomal subunit protein uS13 (RPS18) LDTP04972 5.94  LDD0469 
Splicing factor 3B subunit 1 (SF3B1) LDTP01251 12.04  LDD0469 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 13.77  LDD0469 
Src substrate cortactin (CTTN) LDTP06094 20.00  LDD0469 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 20.00  LDD0469 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 6.13  LDD0469 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 12.69  LDD0469 
Structural maintenance of chromosomes protein 3 (SMC3) LDTP13760 8.39  LDD0469 
Superkiller complex protein 3 (SKIC3) LDTP07574 20.00  LDD0469 
Syntaxin-12 (STX12) LDTP08389 20.00  LDD0469 
Syntaxin-18 (STX18) LDTP13086 20.00  LDD0469 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 12.30  LDD0469 
T-complex protein 1 subunit eta (CCT7) LDTP10990 6.50  LDD0469 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 5.51  LDD0469 
T-complex protein 1 subunit theta (CCT8) LDTP04390 6.30  LDD0469 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 5.04  LDD0469 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 13.72  LDD0469 
Testis-expressed protein 10 (TEX10) LDTP16128 14.15  LDD0469 
Tetraspanin-6 (TSPAN6) LDTP14458 20.00  LDD0484 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 20.00  LDD0469 
Transducin beta-like protein 3 (TBL3) LDTP05647 6.77  LDD0469 
Transformer-2 protein homolog beta (TRA2B) LDTP05036 20.00  LDD0469 
Translocon-associated protein subunit delta (SSR4) LDTP04425 20.00  LDD0469 
Transmembrane protein 43 (TMEM43) LDTP11210 20.00  LDD0469 
Treacle protein (TCOF1) LDTP05867 20.00  LDD0469 
Tubulin beta chain (TUBB) LDTP02205 10.22  LDD0469 
Tubulin beta-2B chain (TUBB2B) LDTP11277 9.71  LDD0469 
Tubulin beta-4B chain (TUBB4B) LDTP05076 8.18  LDD0469 
Ubiquilin-1 (UBQLN1) LDTP13626 20.00  LDD0469 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 20.00  LDD0469 
Vimentin (VIM) LDTP02297 20.00  LDD0469 
WD repeat-containing protein 43 (WDR43) LDTP06305 12.72  LDD0469 
Wings apart-like protein homolog (WAPL) LDTP08094 20.00  LDD0469 
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⏷ Show the Full List of 193 Other

Competitor(s) Related To This Probe

Competitor ID Name Concentration Cell-system Ref
 LDCM0184  Compound 20 160 uM Human normal cells (HEK-293T) [1]
 LDCM0185  Compound 17 200 uM Human normal cells (HEK-293T) [1]
 LDCM0186  Compound 31 160 uM Human normal cells (HEK-293T) [1]
 LDCM0187  Compound 32 160 uM Human normal cells (HEK-293T) [1]
 LDCM0188  Compound 33 160 uM Human normal cells (HEK-293T) [1]

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:200uM; negative probe:200uM
Quantitative Method
SILAC
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:20uM; negative probe:20uM
Quantitative Method
SILAC
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
20 uM
Quantitative Method
SILAC
Competitor Name
Compound 20
Competitor Concentration
160 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
20 uM
Quantitative Method
SILAC
Competitor Name
Compound 17
Competitor Concentration
160 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
  
Experiment 3 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
20 uM
Quantitative Method
SILAC
Competitor Name
Compound 33
Competitor Concentration
160 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
  
Experiment 4 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
20 uM
Quantitative Method
SILAC
Competitor Name
Compound 31
Competitor Concentration
160 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
  
Experiment 5 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
20 uM
Quantitative Method
SILAC
Competitor Name
Compound 32
Competitor Concentration
160 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID
  
Experiment 6 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
200 uM
Quantitative Method
SILAC
Competitor Name
Compound 17
Competitor Concentration
200 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Interaction Atlas ID

References

1 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.