Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | JN0003 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 20 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
SILAC
|
|||||
| Competitor Name | Compound 31 | Competitor Info | ||||
| Competitor Concentration | 160 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03189 | Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) | 15.3 | ||||
| LDTP02198 | Cathepsin D (CTSD) | 14.0 | ||||
| LDTP04471 | Ribosomal protein S6 kinase alpha-3 (RPS6KA3) | 10.4 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 9.8 | ||||
| LDTP05192 | ADP-ribosylation factor 1 (ARF1) | 9.7 | ||||
| LDTP05724 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) | 9.2 | ||||
| LDTP02837 | Beta-galactosidase (GLB1) | 9.1 | ||||
| LDTP02141 | Alpha-galactosidase A (GLA) | 9.0 | ||||
| LDTP04211 | Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) | 8.7 | ||||
| LDTP03139 | Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) | 8.5 | ||||
| LDTP15988 | Probable serine carboxypeptidase CPVL (CPVL) | 8.5 | ||||
| LDTP12610 | Obg-like ATPase 1 (OLA1) | 8.3 | ||||
| LDTP03912 | Trifunctional enzyme subunit alpha, mitochondrial (HADHA) | 7.9 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 7.7 | ||||
| LDTP01773 | Cytochrome c oxidase subunit 2 (MT-CO2) | 7.1 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 6.9 | ||||
| LDTP02602 | Histidine--tRNA ligase, cytoplasmic (HARS1) | 6.6 | ||||
| LDTP03257 | Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) | 6.5 | ||||
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 6.5 | ||||
| LDTP06648 | Lanosterol 14-alpha demethylase (CYP51A1) | 6.2 | ||||
| LDTP02651 | Gamma-interferon-inducible lysosomal thiol reductase (IFI30) | 6.0 | ||||
| LDTP01333 | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) | 5.8 | ||||
| LDTP03842 | Squalene synthase (FDFT1) | 5.7 | ||||
| LDTP05476 | 3-ketodihydrosphingosine reductase (KDSR) | 5.3 | ||||
| LDTP08799 | Lysophosphatidylserine lipase ABHD12 (ABHD12) | 5.0 | ||||
| LDTP06901 | Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) | 4.9 | ||||
| LDTP13751 | Exonuclease 1 (EXO1) | 4.9 | ||||
| LDTP04051 | Nicotinamide phosphoribosyltransferase (NAMPT) | 4.5 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 4.5 | ||||
| LDTP04008 | Endothelin-converting enzyme 1 (ECE1) | 4.5 | ||||
| LDTP03689 | Serine hydroxymethyltransferase, mitochondrial (SHMT2) | 3.6 | ||||
| LDTP02385 | Leukotriene A-4 hydrolase (LTA4H) | 3.3 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 20.2 | ||||
| LDTP14952 | Mpv17-like protein 2 (MPV17L2) | 15.7 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 12.1 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 11.8 | ||||
| LDTP13824 | Voltage-dependent anion-selective channel protein 3 (VDAC3) | 11.0 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 10.0 | ||||
| LDTP02215 | Prosaposin (PSAP) | 9.4 | ||||
| LDTP11213 | Nucleoporin NDC1 (NDC1) | 9.3 | ||||
| LDTP01745 | Putative lipid scramblase CLPTM1 (CLPTM1) | 8.9 | ||||
| LDTP00310 | Syntenin-1 (SDCBP) | 8.6 | ||||
| LDTP06034 | Lysosome membrane protein 2 (SCARB2) | 6.9 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00105 | Protein unc-119 homolog B (UNC119B) | 6.0 | ||||
| LDTP12412 | Reticulon-4 (RTN4) | 5.3 | ||||