Details of the Target

General Information of Target

Target ID LDTP03619
Target Name Stress-induced-phosphoprotein 1 (STIP1)
Gene Name STIP1
Gene ID 10963
Synonyms
Stress-induced-phosphoprotein 1; STI1; Hsc70/Hsp90-organizing protein; Hop; Renal carcinoma antigen NY-REN-11; Transformation-sensitive protein IEF SSP 3521
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYED
GCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLA
ERKFMNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLS
VLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKKKD
FDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIA
KAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLA
LEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEEC
IQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHD
SPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVGLI
AIR
Target Bioclass
Other
Subcellular location
Cytoplasm
Function Acts as a co-chaperone for HSP90AA1. Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90.
Uniprot ID
P31948
Ensemble ID
ENST00000305218.9
HGNC ID
HGNC:11387
ChEMBL ID
CHEMBL4523216

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A2058 SNV: p.Q532Ter DBIA    Probe Info 
G401 SNV: p.E208K DBIA    Probe Info 
MOLT4 SNV: p.Y248C IA-alkyne    Probe Info 
NCIH1703 SNV: p.A302T DBIA    Probe Info 
SNGM SNV: p.Ter544WextTer1 DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 50 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		10.72  LDD0402  [1]
P8
 Probe Info  		10.00  LDD0451  [2]
A-EBA
 Probe Info  		3.76  LDD0215  [3]
CY-1
 Probe Info  		100.00  LDD0243  [4]
CY4
 Probe Info  		56.00  LDD0244  [4]
N1
 Probe Info  		16.61  LDD0242  [4]
TH211
 Probe Info  		Y468(20.00); Y354(5.15)  LDD0257  [5]
TH214
 Probe Info  		Y354(8.95); Y451(5.01)  LDD0258  [5]
TH216
 Probe Info  		Y316(20.00); Y58(20.00); Y323(16.97); Y354(15.03)  LDD0259  [5]
BTD
 Probe Info  		C339(2.43)  LDD1699  [6]
AZ-9
 Probe Info  		E509(0.94); E110(0.94); D358(1.16); K364(0.93)  LDD2208  [7]
ONAyne
 Probe Info  		K50(0.00); K78(0.00); K162(0.00); K239(0.00)  LDD0273  [8]
Probe 1
 Probe Info  		Y27(11.49); Y54(160.04); Y58(292.90); Y95(45.22)  LDD3495  [9]
AHL-Pu-1
 Probe Info  		C62(3.45); C26(5.15)  LDD0170  [10]
HHS-482
 Probe Info  		Y236(0.79); Y27(2.42); Y310(1.24); Y316(1.09)  LDD0285  [11]
HHS-475
 Probe Info  		Y261(0.76); Y269(0.83); Y476(0.87); Y296(0.92)  LDD0264  [12]
HHS-465
 Probe Info  		Y236(10.00); Y261(10.00); Y269(10.00); Y27(10.00)  LDD2237  [13]
DBIA
 Probe Info  		C417(1.75); C420(1.75); C471(1.72); C26(1.13)  LDD0080  [14]
5E-2FA
 Probe Info  		H36(0.00); H479(0.00); H321(0.00); H521(0.00)  LDD2235  [15]
AMP probe
 Probe Info  		K73(0.00); K325(0.00); K229(0.00); K523(0.00)  LDD0200  [16]
ATP probe
 Probe Info  		K73(0.00); K325(0.00); K229(0.00); K523(0.00)  LDD0199  [16]
4-Iodoacetamidophenylacetylene
 Probe Info  		C461(0.00); C26(0.00); C62(0.00); C471(0.00)  LDD0038  [17]
IA-alkyne
 Probe Info  		C370(0.00); C461(0.00); C62(0.00)  LDD0032  [18]
IPIAA_H
 Probe Info  		N.A.  LDD0030  [19]
IPIAA_L
 Probe Info  		C370(0.00); C417(0.00); C461(0.00); C62(0.00)  LDD0031  [19]
Lodoacetamide azide
 Probe Info  		C461(0.00); C471(0.00); C370(0.00); C26(0.00)  LDD0037  [17]
ATP probe
 Probe Info  		K486(0.00); K73(0.00); K239(0.00); K312(0.00)  LDD0035  [20]
NAIA_4
 Probe Info  		C26(0.00); C461(0.00)  LDD2226  [21]
TFBX
 Probe Info  		N.A.  LDD0027  [22]
WYneN
 Probe Info  		C370(0.00); C461(0.00)  LDD0021  [23]
WYneO
 Probe Info  		N.A.  LDD0022  [23]
1d-yne
 Probe Info  		K78(0.00); K381(0.00); K123(0.00)  LDD0356  [24]
Compound 10
 Probe Info  		C26(0.00); C461(0.00)  LDD2216  [25]
ENE
 Probe Info  		N.A.  LDD0006  [23]
IPM
 Probe Info  		C370(0.00); C461(0.00)  LDD0005  [23]
NHS
 Probe Info  		K78(0.00); K317(0.00); K513(0.00); K8(0.00)  LDD0010  [23]
PF-06672131
 Probe Info  		C26(0.00); C62(0.00); C461(0.00)  LDD0017  [26]
SF
 Probe Info  		K434(0.00); K337(0.00); K338(0.00); Y354(0.00)  LDD0028  [27]
STPyne
 Probe Info  		K381(0.00); K429(0.00); K442(0.00); K530(0.00)  LDD0009  [23]
VSF
 Probe Info  		N.A.  LDD0007  [23]
YN-1
 Probe Info  		N.A.  LDD0446  [28]
Phosphinate-6
 Probe Info  		C461(0.00); C62(0.00)  LDD0018  [29]
Ox-W18
 Probe Info  		N.A.  LDD2175  [30]
1c-yne
 Probe Info  		K109(0.00); K442(0.00); K63(0.00); K78(0.00)  LDD0228  [24]
Acrolein
 Probe Info  		C26(0.00); H521(0.00); C461(0.00); C370(0.00)  LDD0217  [31]
Cinnamaldehyde
 Probe Info  		N.A.  LDD0220  [31]
Crotonaldehyde
 Probe Info  		C370(0.00); C403(0.00); C26(0.00)  LDD0219  [31]
Methacrolein
 Probe Info  		C461(0.00); C370(0.00); C26(0.00); C62(0.00)  LDD0218  [31]
W1
 Probe Info  		C26(0.00); C461(0.00); C370(0.00); C62(0.00)  LDD0236  [32]
NAIA_5
 Probe Info  		C461(0.00); C26(0.00); C62(0.00); C471(0.00)  LDD2223  [21]
PAL-AfBPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe11
 Probe Info  		6.51  LDD0471  [33]
FFF probe13
 Probe Info  		10.17  LDD0475  [33]
FFF probe14
 Probe Info  		12.60  LDD0477  [33]
FFF probe2
 Probe Info  		7.50  LDD0463  [33]
FFF probe3
 Probe Info  		6.75  LDD0465  [33]
JN0003
 Probe Info  		6.13  LDD0469  [33]
STS-2
 Probe Info  		N.A.  LDD0138  [34]
VE-P
 Probe Info  		N.A.  LDD0396  [35]
DFG-out-4
 Probe Info  		12.50  LDD0075  [36]
CA
 Probe Info  		4.47  LDD0419  [37]
DA-2
 Probe Info  		N.A.  LDD0070  [38]
STS-1
 Probe Info  		N.A.  LDD0068  [39]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C370(0.42); C403(0.53); C62(0.36); C461(0.70)  LDD2142  [6]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C370(0.58); C403(0.54); C62(0.82); C461(0.71)  LDD2112  [6]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C403(0.62); C62(0.84); C461(0.88); C339(0.49)  LDD2117  [6]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C403(1.18); C339(1.39); C278(1.00)  LDD2152  [6]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C403(1.53); C461(0.75); C339(1.34); C278(1.38)  LDD2103  [6]
 LDCM0025  4SU-RNA DM93 C62(3.45); C26(5.15)  LDD0170  [10]
 LDCM0026  4SU-RNA+native RNA DM93 C62(2.16); C26(3.42)  LDD0171  [10]
 LDCM0562  Abegg_cp(-)-11 HeLa C26(2.21)  LDD0313  [22]
 LDCM0214  AC1 HCT 116 C26(1.15); C370(1.14); C417(1.00); C420(1.00)  LDD0531  [14]
 LDCM0215  AC10 HCT 116 C370(1.08); C417(0.96); C420(0.96); C461(1.05)  LDD0532  [14]
 LDCM0216  AC100 HCT 116 C370(0.77); C417(0.70); C420(0.70); C461(1.07)  LDD0533  [14]
 LDCM0217  AC101 HCT 116 C370(0.70); C417(0.70); C420(0.70); C461(0.92)  LDD0534  [14]
 LDCM0218  AC102 HCT 116 C370(0.71); C417(0.86); C420(0.86); C461(1.09)  LDD0535  [14]
 LDCM0219  AC103 HCT 116 C370(0.67); C417(0.66); C420(0.66); C461(1.14)  LDD0536  [14]
 LDCM0220  AC104 HCT 116 C370(0.81); C417(1.01); C420(1.01); C461(1.02)  LDD0537  [14]
 LDCM0221  AC105 HCT 116 C370(0.73); C417(0.64); C420(0.64); C461(1.07)  LDD0538  [14]
 LDCM0222  AC106 HCT 116 C370(0.85); C417(0.80); C420(0.80); C461(1.16)  LDD0539  [14]
 LDCM0223  AC107 HCT 116 C370(0.80); C417(0.86); C420(0.86); C461(1.20)  LDD0540  [14]
 LDCM0224  AC108 HCT 116 C370(0.76); C417(0.83); C420(0.83); C461(1.07)  LDD0541  [14]
 LDCM0225  AC109 HCT 116 C370(0.78); C417(0.96); C420(0.96); C461(0.89)  LDD0542  [14]
 LDCM0226  AC11 HCT 116 C370(1.00); C417(0.97); C420(0.97); C461(0.98)  LDD0543  [14]
 LDCM0227  AC110 HCT 116 C370(0.71); C417(0.61); C420(0.61); C461(1.01)  LDD0544  [14]
 LDCM0228  AC111 HCT 116 C370(0.68); C417(0.79); C420(0.79); C461(0.93)  LDD0545  [14]
 LDCM0229  AC112 HCT 116 C370(0.72); C417(0.88); C420(0.88); C461(1.15)  LDD0546  [14]
 LDCM0230  AC113 HCT 116 C26(0.89); C370(1.13); C417(1.02); C420(1.02)  LDD0547  [14]
 LDCM0231  AC114 HCT 116 C26(0.97); C370(1.08); C417(0.83); C420(0.83)  LDD0548  [14]
 LDCM0232  AC115 HCT 116 C26(1.06); C370(1.14); C417(0.79); C420(0.79)  LDD0549  [14]
 LDCM0233  AC116 HCT 116 C26(1.03); C370(1.08); C417(0.87); C420(0.87)  LDD0550  [14]
 LDCM0234  AC117 HCT 116 C26(1.03); C370(1.31); C417(0.92); C420(0.92)  LDD0551  [14]
 LDCM0235  AC118 HCT 116 C26(1.10); C370(1.08); C417(0.93); C420(0.93)  LDD0552  [14]
 LDCM0236  AC119 HCT 116 C26(1.01); C370(1.22); C417(0.84); C420(0.84)  LDD0553  [14]
 LDCM0237  AC12 HCT 116 C370(1.24); C417(1.06); C420(1.06); C461(0.99)  LDD0554  [14]
 LDCM0238  AC120 HCT 116 C26(1.04); C370(1.07); C417(0.76); C420(0.76)  LDD0555  [14]
 LDCM0239  AC121 HCT 116 C26(1.01); C370(1.22); C417(0.83); C420(0.83)  LDD0556  [14]
 LDCM0240  AC122 HCT 116 C26(0.95); C370(1.20); C417(0.96); C420(0.96)  LDD0557  [14]
 LDCM0241  AC123 HCT 116 C26(0.90); C370(1.28); C417(0.87); C420(0.87)  LDD0558  [14]
 LDCM0242  AC124 HCT 116 C26(0.94); C370(1.34); C417(0.96); C420(0.96)  LDD0559  [14]
 LDCM0243  AC125 HCT 116 C26(1.07); C370(1.20); C417(0.91); C420(0.91)  LDD0560  [14]
 LDCM0244  AC126 HCT 116 C26(0.98); C370(1.16); C417(0.78); C420(0.78)  LDD0561  [14]
 LDCM0245  AC127 HCT 116 C26(0.95); C370(1.40); C417(0.81); C420(0.81)  LDD0562  [14]
 LDCM0246  AC128 HCT 116 C370(1.07); C417(0.97); C420(0.97); C461(1.19)  LDD0563  [14]
 LDCM0247  AC129 HCT 116 C370(1.33); C417(1.19); C420(1.19); C461(1.00)  LDD0564  [14]
 LDCM0249  AC130 HCT 116 C370(1.18); C417(1.05); C420(1.05); C461(1.28)  LDD0566  [14]
 LDCM0250  AC131 HCT 116 C370(1.32); C417(1.11); C420(1.11); C461(0.87)  LDD0567  [14]
 LDCM0251  AC132 HCT 116 C370(1.40); C417(0.96); C420(0.96); C461(1.17)  LDD0568  [14]
 LDCM0252  AC133 HCT 116 C370(1.05); C417(0.95); C420(0.95); C461(1.19)  LDD0569  [14]
 LDCM0253  AC134 HCT 116 C370(1.08); C417(0.83); C420(0.83); C461(1.16)  LDD0570  [14]
 LDCM0254  AC135 HCT 116 C370(1.22); C417(0.76); C420(0.76); C461(1.11)  LDD0571  [14]
 LDCM0255  AC136 HCT 116 C370(1.25); C417(0.88); C420(0.88); C461(1.31)  LDD0572  [14]
 LDCM0256  AC137 HCT 116 C370(1.12); C417(0.84); C420(0.84); C461(1.25)  LDD0573  [14]
 LDCM0257  AC138 HCT 116 C370(1.33); C417(0.79); C420(0.79); C461(1.63)  LDD0574  [14]
 LDCM0258  AC139 HCT 116 C370(1.61); C417(0.90); C420(0.90); C461(1.24)  LDD0575  [14]
 LDCM0259  AC14 HCT 116 C370(1.03); C417(1.23); C420(1.23); C461(0.85)  LDD0576  [14]
 LDCM0260  AC140 HCT 116 C370(1.39); C417(0.79); C420(0.79); C461(1.37)  LDD0577  [14]
 LDCM0261  AC141 HCT 116 C370(1.47); C417(0.78); C420(0.78); C461(1.36)  LDD0578  [14]
 LDCM0262  AC142 HCT 116 C370(1.21); C417(1.03); C420(1.03); C461(1.18)  LDD0579  [14]
 LDCM0263  AC143 HCT 116 C417(0.90); C420(0.90); C471(0.90); C62(0.96)  LDD0580  [14]
 LDCM0264  AC144 HCT 116 C420(0.75); C417(0.77); C471(0.99); C62(1.02)  LDD0581  [14]
 LDCM0265  AC145 HCT 116 C417(0.85); C420(0.86); C26(0.98); C471(1.00)  LDD0582  [14]
 LDCM0266  AC146 HCT 116 C417(0.87); C420(0.92); C471(0.93); C62(1.01)  LDD0583  [14]
 LDCM0267  AC147 HCT 116 C471(0.82); C417(0.84); C420(0.85); C62(0.97)  LDD0584  [14]
 LDCM0268  AC148 HCT 116 C471(0.59); C417(0.68); C420(0.68); C62(0.93)  LDD0585  [14]
 LDCM0269  AC149 HCT 116 C417(0.69); C471(0.73); C420(0.75); C26(1.09)  LDD0586  [14]
 LDCM0270  AC15 HCT 116 C461(0.81); C370(0.95); C62(1.04); C471(1.14)  LDD0587  [14]
 LDCM0271  AC150 HCT 116 C420(0.86); C417(0.87); C471(1.02); C26(1.09)  LDD0588  [14]
 LDCM0272  AC151 HCT 116 C420(0.76); C417(0.78); C370(0.92); C471(0.94)  LDD0589  [14]
 LDCM0273  AC152 HCT 116 C471(0.73); C420(0.81); C417(0.84); C62(1.03)  LDD0590  [14]
 LDCM0274  AC153 HCT 116 C471(0.60); C420(0.66); C417(0.68); C26(1.03)  LDD0591  [14]
 LDCM0621  AC154 HCT 116 C26(0.96); C370(1.09); C417(0.86); C420(0.89)  LDD2158  [14]
 LDCM0622  AC155 HCT 116 C26(1.35); C370(1.05); C417(0.92); C420(0.91)  LDD2159  [14]
 LDCM0623  AC156 HCT 116 C26(1.16); C370(1.23); C417(1.01); C420(1.03)  LDD2160  [14]
 LDCM0624  AC157 HCT 116 C26(0.77); C370(1.11); C417(1.06); C420(1.06)  LDD2161  [14]
 LDCM0276  AC17 HCT 116 C420(0.96); C417(0.97); C370(1.02); C461(1.05)  LDD0593  [14]
 LDCM0277  AC18 HCT 116 C420(0.68); C417(0.76); C471(0.80); C461(1.20)  LDD0594  [14]
 LDCM0278  AC19 HCT 116 C420(0.92); C417(0.95); C471(1.02); C461(1.07)  LDD0595  [14]
 LDCM0279  AC2 HCT 116 C417(0.92); C420(0.92); C370(1.00); C26(1.05)  LDD0596  [14]
 LDCM0280  AC20 HCT 116 C417(0.75); C420(0.77); C370(0.94); C461(1.05)  LDD0597  [14]
 LDCM0281  AC21 HCT 116 C420(0.75); C417(0.76); C370(1.04); C461(1.04)  LDD0598  [14]
 LDCM0282  AC22 HCT 116 C420(0.82); C417(0.84); C370(1.03); C461(1.04)  LDD0599  [14]
 LDCM0283  AC23 HCT 116 C417(0.79); C420(0.79); C471(1.02); C370(1.04)  LDD0600  [14]
 LDCM0284  AC24 HCT 116 C461(0.87); C370(1.03); C420(1.07); C471(1.10)  LDD0601  [14]
 LDCM0285  AC25 HCT 116 C370(0.91); C417(1.06); C420(1.06); C62(1.14)  LDD0602  [14]
 LDCM0286  AC26 HCT 116 C417(0.82); C420(0.82); C370(0.85); C471(1.18)  LDD0603  [14]
 LDCM0287  AC27 HCT 116 C370(0.87); C417(0.94); C420(0.94); C461(1.15)  LDD0604  [14]
 LDCM0288  AC28 HCT 116 C370(0.81); C417(0.91); C420(0.91); C471(1.06)  LDD0605  [14]
 LDCM0289  AC29 HCT 116 C417(0.70); C420(0.70); C370(0.91); C62(1.23)  LDD0606  [14]
 LDCM0290  AC3 HCT 116 C370(1.00); C417(1.03); C420(1.03); C26(1.05)  LDD0607  [14]
 LDCM0291  AC30 HCT 116 C417(0.80); C420(0.80); C370(1.02); C471(1.30)  LDD0608  [14]
 LDCM0292  AC31 HCT 116 C370(0.87); C417(1.04); C420(1.04); C461(1.23)  LDD0609  [14]
 LDCM0293  AC32 HCT 116 C370(1.09); C417(1.13); C420(1.13); C471(1.15)  LDD0610  [14]
 LDCM0294  AC33 HCT 116 C370(0.86); C417(0.90); C420(0.90); C471(1.19)  LDD0611  [14]
 LDCM0295  AC34 HCT 116 C417(0.82); C420(0.82); C370(0.92); C471(0.99)  LDD0612  [14]
 LDCM0296  AC35 HCT 116 C62(0.88); C420(0.89); C461(0.90); C370(0.92)  LDD0613  [14]
 LDCM0297  AC36 HCT 116 C370(0.79); C420(0.80); C417(0.84); C62(0.93)  LDD0614  [14]
 LDCM0298  AC37 HCT 116 C370(0.82); C420(0.93); C62(0.95); C417(1.01)  LDD0615  [14]
 LDCM0299  AC38 HCT 116 C461(0.87); C420(0.91); C417(0.95); C62(0.96)  LDD0616  [14]
 LDCM0300  AC39 HCT 116 C420(0.77); C417(0.82); C370(0.86); C471(0.96)  LDD0617  [14]
 LDCM0301  AC4 HCT 116 C370(0.93); C417(0.97); C420(0.97); C26(1.15)  LDD0618  [14]
 LDCM0302  AC40 HCT 116 C420(0.68); C417(0.72); C370(0.85); C471(0.91)  LDD0619  [14]
 LDCM0303  AC41 HCT 116 C417(0.72); C420(0.72); C370(0.80); C471(0.93)  LDD0620  [14]
 LDCM0304  AC42 HCT 116 C420(0.73); C417(0.76); C461(0.92); C62(0.98)  LDD0621  [14]
 LDCM0305  AC43 HCT 116 C417(0.81); C420(0.87); C370(0.92); C461(1.06)  LDD0622  [14]
 LDCM0306  AC44 HCT 116 C417(0.71); C420(0.74); C471(0.95); C461(0.96)  LDD0623  [14]
 LDCM0307  AC45 HCT 116 C420(0.68); C417(0.69); C471(0.98); C370(0.99)  LDD0624  [14]
 LDCM0308  AC46 HCT 116 C417(0.90); C420(0.91); C62(1.04); C370(1.04)  LDD0625  [14]
 LDCM0309  AC47 HCT 116 C417(0.79); C420(0.81); C471(0.97); C370(1.07)  LDD0626  [14]
 LDCM0310  AC48 HCT 116 C62(1.12); C420(1.16); C370(1.16); C417(1.18)  LDD0627  [14]
 LDCM0311  AC49 HCT 116 C417(0.64); C420(0.71); C471(0.78); C370(0.97)  LDD0628  [14]
 LDCM0312  AC5 HCT 116 C417(0.69); C420(0.69); C370(1.00); C26(1.12)  LDD0629  [14]
 LDCM0313  AC50 HCT 116 C471(0.88); C417(0.90); C420(0.91); C370(1.11)  LDD0630  [14]
 LDCM0314  AC51 HCT 116 C417(0.92); C420(0.93); C461(0.93); C62(0.94)  LDD0631  [14]
 LDCM0315  AC52 HCT 116 C417(0.94); C420(1.02); C62(1.07); C370(1.23)  LDD0632  [14]
 LDCM0316  AC53 HCT 116 C417(0.65); C420(0.69); C471(0.89); C370(1.05)  LDD0633  [14]
 LDCM0317  AC54 HCT 116 C420(0.95); C417(0.97); C471(1.09); C370(1.11)  LDD0634  [14]
 LDCM0318  AC55 HCT 116 C417(0.61); C420(0.68); C471(0.77); C370(1.04)  LDD0635  [14]
 LDCM0319  AC56 HCT 116 C417(0.55); C420(0.58); C471(0.70); C370(1.19)  LDD0636  [14]
 LDCM0320  AC57 HCT 116 C417(0.83); C420(0.83); C471(0.84); C370(1.07)  LDD0637  [14]
 LDCM0321  AC58 HCT 116 C417(0.76); C420(0.76); C370(1.01); C471(1.04)  LDD0638  [14]
 LDCM0322  AC59 HCT 116 C471(0.75); C370(1.02); C417(1.08); C420(1.08)  LDD0639  [14]
 LDCM0323  AC6 HCT 116 C417(0.91); C420(0.91); C370(0.97); C461(1.09)  LDD0640  [14]
 LDCM0324  AC60 HCT 116 C417(0.87); C420(0.87); C471(0.96); C370(1.13)  LDD0641  [14]
 LDCM0325  AC61 HCT 116 C417(1.01); C420(1.01); C370(1.35); C26(1.42)  LDD0642  [14]
 LDCM0326  AC62 HCT 116 C471(0.81); C417(1.01); C420(1.01); C370(1.05)  LDD0643  [14]
 LDCM0327  AC63 HCT 116 C417(0.87); C420(0.87); C471(0.97); C370(1.12)  LDD0644  [14]
 LDCM0328  AC64 HCT 116 C471(0.66); C417(0.77); C420(0.77); C370(0.95)  LDD0645  [14]
 LDCM0329  AC65 HCT 116 C471(0.43); C417(0.73); C420(0.73); C370(1.17)  LDD0646  [14]
 LDCM0330  AC66 HCT 116 C471(0.54); C417(1.07); C420(1.07); C370(1.10)  LDD0647  [14]
 LDCM0331  AC67 HCT 116 C471(0.21); C417(0.80); C420(0.80); C370(0.92)  LDD0648  [14]
 LDCM0332  AC68 HCT 116 C417(0.87); C420(0.87); C461(1.10); C370(1.14)  LDD0649  [14]
 LDCM0333  AC69 HCT 116 C26(0.74); C417(0.80); C420(0.80); C370(0.93)  LDD0650  [14]
 LDCM0334  AC7 HCT 116 C62(0.94); C417(0.95); C420(0.95); C370(1.05)  LDD0651  [14]
 LDCM0335  AC70 HCT 116 C417(0.72); C420(0.72); C370(0.81); C26(0.91)  LDD0652  [14]
 LDCM0336  AC71 HCT 116 C417(0.84); C420(0.84); C461(0.85); C370(0.92)  LDD0653  [14]
 LDCM0337  AC72 HCT 116 C417(0.73); C420(0.73); C370(0.85); C26(0.94)  LDD0654  [14]
 LDCM0338  AC73 HCT 116 C417(0.54); C420(0.54); C370(0.66); C26(0.84)  LDD0655  [14]
 LDCM0339  AC74 HCT 116 C417(0.55); C420(0.55); C26(0.68); C370(0.73)  LDD0656  [14]
 LDCM0340  AC75 HCT 116 C417(0.47); C420(0.47); C370(0.62); C471(0.98)  LDD0657  [14]
 LDCM0341  AC76 HCT 116 C370(0.66); C417(0.68); C420(0.68); C26(0.93)  LDD0658  [14]
 LDCM0342  AC77 HCT 116 C417(0.65); C420(0.65); C26(0.91); C370(0.94)  LDD0659  [14]
 LDCM0343  AC78 HCT 116 C26(0.81); C417(0.83); C420(0.83); C370(0.93)  LDD0660  [14]
 LDCM0344  AC79 HCT 116 C417(0.82); C420(0.82); C370(0.92); C461(0.95)  LDD0661  [14]
 LDCM0345  AC8 HCT 116 C62(0.81); C417(0.92); C420(0.92); C370(1.15)  LDD0662  [14]
 LDCM0346  AC80 HCT 116 C417(0.82); C420(0.82); C370(0.92); C62(1.00)  LDD0663  [14]
 LDCM0347  AC81 HCT 116 C417(0.81); C420(0.81); C62(0.93); C370(0.95)  LDD0664  [14]
 LDCM0348  AC82 HCT 116 C417(0.44); C420(0.44); C370(0.72); C26(0.87)  LDD0665  [14]
 LDCM0349  AC83 HCT 116 C417(0.50); C420(0.50); C370(1.04); C62(1.15)  LDD0666  [14]
 LDCM0350  AC84 HCT 116 C417(0.60); C420(0.60); C370(0.90); C62(1.11)  LDD0667  [14]
 LDCM0351  AC85 HCT 116 C417(0.69); C420(0.69); C370(0.91); C62(1.08)  LDD0668  [14]
 LDCM0352  AC86 HCT 116 C417(0.70); C420(0.70); C370(0.88); C62(1.04)  LDD0669  [14]
 LDCM0353  AC87 HCT 116 C417(0.84); C420(0.84); C26(0.96); C62(1.01)  LDD0670  [14]
 LDCM0354  AC88 HCT 116 C417(0.74); C420(0.74); C370(1.00); C26(1.05)  LDD0671  [14]
 LDCM0355  AC89 HCT 116 C417(0.81); C420(0.81); C370(0.97); C62(1.01)  LDD0672  [14]
 LDCM0357  AC90 HCT 116 C417(0.92); C420(0.92); C461(1.01); C370(1.07)  LDD0674  [14]
 LDCM0358  AC91 HCT 116 C417(0.80); C420(0.80); C370(0.89); C26(1.06)  LDD0675  [14]
 LDCM0359  AC92 HCT 116 C417(0.71); C420(0.71); C370(0.97); C62(1.16)  LDD0676  [14]
 LDCM0360  AC93 HCT 116 C417(0.69); C420(0.69); C370(1.10); C26(1.15)  LDD0677  [14]
 LDCM0361  AC94 HCT 116 C417(0.73); C420(0.73); C370(0.87); C461(0.98)  LDD0678  [14]
 LDCM0362  AC95 HCT 116 C417(0.89); C420(0.89); C62(0.97); C26(0.98)  LDD0679  [14]
 LDCM0363  AC96 HCT 116 C370(0.88); C417(0.99); C420(0.99); C62(1.04)  LDD0680  [14]
 LDCM0364  AC97 HCT 116 C417(0.75); C420(0.75); C370(1.01); C26(1.10)  LDD0681  [14]
 LDCM0365  AC98 HCT 116 C471(0.34); C370(0.43); C417(0.64); C420(0.64)  LDD0682  [14]
 LDCM0366  AC99 HCT 116 C471(0.57); C417(0.61); C420(0.61); C370(0.69)  LDD0683  [14]
 LDCM0545  Acetamide MDA-MB-231 C403(0.37); C339(0.38); C278(0.27)  LDD2138  [6]
 LDCM0520  AKOS000195272 MDA-MB-231 C370(0.71); C403(0.87); C62(0.78); C461(0.65)  LDD2113  [6]
 LDCM0248  AKOS034007472 HCT 116 C370(0.93); C417(1.13); C420(1.13); C461(0.93)  LDD0565  [14]
 LDCM0356  AKOS034007680 HCT 116 C370(0.89); C62(0.96); C461(0.97); C417(1.01)  LDD0673  [14]
 LDCM0275  AKOS034007705 HCT 116 C461(0.95); C370(1.09); C417(1.14); C420(1.14)  LDD0592  [14]
 LDCM0020  ARS-1620 HCC44 C62(1.25); C370(1.04); C471(1.06)  LDD2171  [14]
 LDCM0498  BS-3668 MDA-MB-231 C403(0.66); C339(0.52); C278(0.58)  LDD2091  [6]
 LDCM0164  Camptothecin MCF-7 4.47  LDD0419  [37]
 LDCM0108  Chloroacetamide HeLa C26(0.00); H101(0.00); H521(0.00); H382(0.00)  LDD0222  [31]
 LDCM0632  CL-Sc Hep-G2 C26(3.12); C370(1.22); C471(0.96); C461(0.88)  LDD2227  [21]
 LDCM0367  CL1 HCT 116 C26(0.82); C471(0.86); C461(0.94); C62(0.98)  LDD0684  [14]
 LDCM0368  CL10 HCT 116 C471(0.53); C417(0.70); C420(0.70); C370(1.05)  LDD0685  [14]
 LDCM0369  CL100 HCT 116 C417(0.90); C420(0.90); C370(0.94); C62(1.13)  LDD0686  [14]
 LDCM0370  CL101 HCT 116 C461(0.88); C370(0.96); C62(0.98); C471(1.12)  LDD0687  [14]
 LDCM0371  CL102 HCT 116 C370(0.77); C461(0.80); C62(0.87); C417(0.98)  LDD0688  [14]
 LDCM0372  CL103 HCT 116 C62(0.84); C461(0.84); C370(1.02); C471(1.12)  LDD0689  [14]
 LDCM0373  CL104 HCT 116 C461(0.86); C370(0.95); C417(1.10); C420(1.10)  LDD0690  [14]
 LDCM0374  CL105 HCT 116 C417(0.75); C420(0.75); C471(0.81); C370(1.00)  LDD0691  [14]
 LDCM0375  CL106 HCT 116 C471(0.64); C420(0.70); C417(0.74); C370(1.01)  LDD0692  [14]
 LDCM0376  CL107 HCT 116 C420(0.74); C417(0.76); C471(0.89); C370(1.17)  LDD0693  [14]
 LDCM0377  CL108 HCT 116 C417(0.66); C420(0.67); C471(0.73); C370(1.01)  LDD0694  [14]
 LDCM0378  CL109 HCT 116 C420(0.77); C417(0.81); C471(0.91); C370(0.97)  LDD0695  [14]
 LDCM0379  CL11 HCT 116 C471(0.72); C417(0.83); C420(0.83); C370(1.08)  LDD0696  [14]
 LDCM0380  CL110 HCT 116 C471(0.72); C420(0.86); C370(0.94); C417(1.00)  LDD0697  [14]
 LDCM0381  CL111 HCT 116 C420(0.78); C417(0.84); C471(0.88); C370(1.05)  LDD0698  [14]
 LDCM0382  CL112 HCT 116 C370(0.87); C417(0.95); C420(0.95); C461(1.03)  LDD0699  [14]
 LDCM0383  CL113 HCT 116 C417(0.84); C420(0.84); C370(0.94); C471(1.12)  LDD0700  [14]
 LDCM0384  CL114 HCT 116 C417(0.92); C420(0.92); C370(0.94); C471(1.25)  LDD0701  [14]
 LDCM0385  CL115 HCT 116 C417(0.76); C420(0.76); C471(0.84); C370(0.89)  LDD0702  [14]
 LDCM0386  CL116 HCT 116 C417(1.00); C420(1.00); C370(1.01); C471(1.03)  LDD0703  [14]
 LDCM0387  CL117 HCT 116 C420(0.58); C417(0.61); C471(0.85); C370(0.91)  LDD0704  [14]
 LDCM0388  CL118 HCT 116 C420(0.83); C417(0.88); C370(0.88); C62(1.02)  LDD0705  [14]
 LDCM0389  CL119 HCT 116 C420(0.84); C417(0.88); C370(0.91); C62(1.11)  LDD0706  [14]
 LDCM0390  CL12 HCT 116 C417(0.73); C420(0.73); C471(0.80); C370(1.05)  LDD0707  [14]
 LDCM0391  CL120 HCT 116 C417(0.85); C420(0.87); C461(0.91); C370(0.93)  LDD0708  [14]
 LDCM0392  CL121 HCT 116 C370(0.86); C420(0.97); C471(0.99); C417(1.16)  LDD0709  [14]
 LDCM0393  CL122 HCT 116 C417(0.79); C420(0.87); C471(0.87); C370(1.10)  LDD0710  [14]
 LDCM0394  CL123 HCT 116 C417(0.76); C471(0.78); C420(0.79); C370(0.95)  LDD0711  [14]
 LDCM0395  CL124 HCT 116 C417(0.64); C420(0.68); C471(0.94); C370(1.07)  LDD0712  [14]
 LDCM0396  CL125 HCT 116 C417(0.91); C420(0.91); C370(1.04); C471(1.06)  LDD0713  [14]
 LDCM0397  CL126 HCT 116 C417(0.78); C420(0.78); C370(1.06); C26(1.16)  LDD0714  [14]
 LDCM0398  CL127 HCT 116 C417(0.84); C420(0.84); C26(1.06); C471(1.12)  LDD0715  [14]
 LDCM0399  CL128 HCT 116 C417(0.80); C420(0.80); C370(0.93); C471(0.95)  LDD0716  [14]
 LDCM0400  CL13 HCT 116 C471(0.82); C417(0.92); C420(0.92); C370(1.03)  LDD0717  [14]
 LDCM0401  CL14 HCT 116 C417(0.90); C420(0.90); C471(0.93); C26(0.94)  LDD0718  [14]
 LDCM0402  CL15 HCT 116 C471(0.61); C26(0.67); C370(0.87); C62(0.88)  LDD0719  [14]
 LDCM0403  CL16 HCT 116 C370(0.78); C417(0.78); C420(0.78); C471(1.04)  LDD0720  [14]
 LDCM0404  CL17 HCT 116 C417(0.93); C420(0.93); C471(0.95); C62(1.03)  LDD0721  [14]
 LDCM0405  CL18 HCT 116 C461(1.18); C62(1.24); C417(1.26); C420(1.26)  LDD0722  [14]
 LDCM0406  CL19 HCT 116 C461(0.88); C417(0.97); C420(0.97); C471(1.00)  LDD0723  [14]
 LDCM0407  CL2 HCT 116 C471(0.87); C26(0.88); C370(1.09); C62(1.09)  LDD0724  [14]
 LDCM0408  CL20 HCT 116 C471(1.09); C417(1.11); C420(1.11); C62(1.12)  LDD0725  [14]
 LDCM0409  CL21 HCT 116 C471(0.77); C461(0.87); C417(0.90); C420(0.90)  LDD0726  [14]
 LDCM0410  CL22 HCT 116 C471(0.60); C417(0.77); C420(0.77); C461(0.94)  LDD0727  [14]
 LDCM0411  CL23 HCT 116 C417(0.85); C420(0.85); C471(1.11); C461(1.20)  LDD0728  [14]
 LDCM0412  CL24 HCT 116 C26(1.41); C417(1.06); C420(1.06); C461(1.13)  LDD0729  [14]
 LDCM0413  CL25 HCT 116 C26(1.39); C417(0.82); C420(0.82); C461(1.06)  LDD0730  [14]
 LDCM0414  CL26 HCT 116 C26(1.26); C417(0.60); C420(0.60); C461(1.33)  LDD0731  [14]
 LDCM0415  CL27 HCT 116 C26(1.31); C417(1.16); C420(1.16); C461(1.05)  LDD0732  [14]
 LDCM0416  CL28 HCT 116 C26(1.33); C417(0.91); C420(0.91); C461(1.06)  LDD0733  [14]
 LDCM0417  CL29 HCT 116 C26(1.36); C417(1.10); C420(1.10); C461(1.00)  LDD0734  [14]
 LDCM0418  CL3 HCT 116 C26(0.93); C370(1.06); C417(1.19); C420(1.19)  LDD0735  [14]
 LDCM0419  CL30 HCT 116 C26(1.31); C417(0.95); C420(0.95); C461(1.00)  LDD0736  [14]
 LDCM0420  CL31 HCT 116 C420(1.02); C461(0.98); C471(1.28); C62(0.89)  LDD0737  [14]
 LDCM0421  CL32 HCT 116 C370(0.91); C417(0.92); C420(0.86); C461(1.21)  LDD0738  [14]
 LDCM0422  CL33 HCT 116 C370(0.89); C417(0.91); C420(0.87); C461(1.38)  LDD0739  [14]
 LDCM0423  CL34 HCT 116 C370(0.82); C417(0.96); C420(0.94); C461(1.06)  LDD0740  [14]
 LDCM0424  CL35 HCT 116 C370(0.81); C417(0.66); C420(0.69); C461(1.12)  LDD0741  [14]
 LDCM0425  CL36 HCT 116 C370(0.90); C417(1.60); C420(1.21); C461(1.12)  LDD0742  [14]
 LDCM0426  CL37 HCT 116 C370(1.00); C417(1.48); C420(1.17); C461(1.14)  LDD0743  [14]
 LDCM0428  CL39 HCT 116 C370(0.85); C417(0.90); C420(0.87); C461(1.38)  LDD0745  [14]
 LDCM0429  CL4 HCT 116 C26(1.02); C370(0.87); C417(1.08); C420(1.08)  LDD0746  [14]
 LDCM0430  CL40 HCT 116 C370(0.89); C417(1.00); C420(0.84); C461(1.22)  LDD0747  [14]
 LDCM0431  CL41 HCT 116 C370(1.13); C417(1.45); C420(1.13); C461(1.06)  LDD0748  [14]
 LDCM0432  CL42 HCT 116 C370(1.28); C417(1.61); C420(1.25); C461(2.09)  LDD0749  [14]
 LDCM0433  CL43 HCT 116 C370(1.13); C417(1.24); C420(1.14); C461(1.26)  LDD0750  [14]
 LDCM0434  CL44 HCT 116 C370(1.06); C417(1.95); C420(1.40); C461(1.12)  LDD0751  [14]
 LDCM0435  CL45 HCT 116 C370(1.12); C417(1.46); C420(1.14); C461(1.34)  LDD0752  [14]
 LDCM0436  CL46 HCT 116 C370(1.13); C417(1.13); C420(1.13); C461(1.23)  LDD0753  [14]
 LDCM0437  CL47 HCT 116 C370(1.37); C417(1.25); C420(1.25); C461(1.26)  LDD0754  [14]
 LDCM0438  CL48 HCT 116 C370(1.25); C417(1.27); C420(1.27); C461(1.28)  LDD0755  [14]
 LDCM0439  CL49 HCT 116 C370(1.04); C417(1.35); C420(1.35); C461(0.93)  LDD0756  [14]
 LDCM0440  CL5 HCT 116 C26(0.99); C370(1.21); C417(1.14); C420(1.14)  LDD0757  [14]
 LDCM0441  CL50 HCT 116 C370(1.23); C417(1.42); C420(1.42); C461(1.04)  LDD0758  [14]
 LDCM0442  CL51 HCT 116 C370(1.16); C417(1.36); C420(1.36); C461(1.03)  LDD0759  [14]
 LDCM0443  CL52 HCT 116 C370(0.94); C417(1.17); C420(1.17); C461(1.06)  LDD0760  [14]
 LDCM0444  CL53 HCT 116 C370(1.00); C417(1.12); C420(1.12); C461(1.03)  LDD0761  [14]
 LDCM0445  CL54 HCT 116 C370(1.14); C417(1.33); C420(1.33); C461(1.19)  LDD0762  [14]
 LDCM0446  CL55 HCT 116 C370(1.19); C417(1.22); C420(1.22); C461(1.07)  LDD0763  [14]
 LDCM0447  CL56 HCT 116 C370(1.35); C417(1.17); C420(1.17); C461(1.22)  LDD0764  [14]
 LDCM0448  CL57 HCT 116 C370(1.19); C417(1.35); C420(1.35); C461(0.96)  LDD0765  [14]
 LDCM0449  CL58 HCT 116 C370(1.01); C417(1.25); C420(1.25); C461(1.09)  LDD0766  [14]
 LDCM0450  CL59 HCT 116 C370(0.93); C417(1.19); C420(1.19); C461(1.02)  LDD0767  [14]
 LDCM0451  CL6 HCT 116 C26(1.08); C370(1.03); C417(0.96); C420(0.96)  LDD0768  [14]
 LDCM0452  CL60 HCT 116 C370(1.33); C417(1.24); C420(1.24); C461(1.06)  LDD0769  [14]
 LDCM0453  CL61 HCT 116 C26(1.04); C370(0.95); C417(0.88); C420(0.88)  LDD0770  [14]
 LDCM0454  CL62 HCT 116 C26(1.03); C370(1.02); C417(0.83); C420(0.83)  LDD0771  [14]
 LDCM0455  CL63 HCT 116 C26(1.20); C370(1.05); C417(0.82); C420(0.82)  LDD0772  [14]
 LDCM0456  CL64 HCT 116 C26(1.03); C370(0.96); C417(0.77); C420(0.77)  LDD0773  [14]
 LDCM0457  CL65 HCT 116 C26(1.08); C370(1.05); C417(0.71); C420(0.71)  LDD0774  [14]
 LDCM0458  CL66 HCT 116 C26(1.34); C370(1.06); C417(1.05); C420(1.05)  LDD0775  [14]
 LDCM0459  CL67 HCT 116 C26(1.16); C370(0.99); C417(0.93); C420(0.93)  LDD0776  [14]
 LDCM0460  CL68 HCT 116 C26(1.15); C370(1.06); C417(0.80); C420(0.80)  LDD0777  [14]
 LDCM0461  CL69 HCT 116 C26(0.99); C370(1.14); C417(0.90); C420(0.90)  LDD0778  [14]
 LDCM0462  CL7 HCT 116 C26(1.14); C370(1.13); C417(0.81); C420(0.81)  LDD0779  [14]
 LDCM0463  CL70 HCT 116 C26(1.05); C370(1.07); C417(0.87); C420(0.87)  LDD0780  [14]
 LDCM0464  CL71 HCT 116 C26(1.13); C370(1.04); C417(0.76); C420(0.76)  LDD0781  [14]
 LDCM0465  CL72 HCT 116 C26(0.99); C370(1.06); C417(0.60); C420(0.60)  LDD0782  [14]
 LDCM0466  CL73 HCT 116 C26(1.18); C370(0.99); C417(0.97); C420(0.97)  LDD0783  [14]
 LDCM0467  CL74 HCT 116 C26(1.04); C370(0.98); C417(0.95); C420(0.95)  LDD0784  [14]
 LDCM0469  CL76 HCT 116 C26(1.11); C370(1.07); C417(0.87); C420(0.87)  LDD0786  [14]
 LDCM0470  CL77 HCT 116 C26(1.07); C370(0.98); C417(0.90); C420(0.90)  LDD0787  [14]
 LDCM0471  CL78 HCT 116 C26(1.13); C370(1.13); C417(0.86); C420(0.86)  LDD0788  [14]
 LDCM0472  CL79 HCT 116 C26(1.21); C370(0.85); C417(0.88); C420(0.88)  LDD0789  [14]
 LDCM0473  CL8 HCT 116 C26(1.30); C370(1.01); C417(0.61); C420(0.61)  LDD0790  [14]
 LDCM0474  CL80 HCT 116 C26(1.03); C370(1.38); C417(1.00); C420(1.00)  LDD0791  [14]
 LDCM0475  CL81 HCT 116 C26(1.13); C370(0.99); C417(0.94); C420(0.94)  LDD0792  [14]
 LDCM0476  CL82 HCT 116 C26(1.39); C370(0.85); C417(0.87); C420(0.87)  LDD0793  [14]
 LDCM0477  CL83 HCT 116 C26(1.45); C370(0.97); C417(0.80); C420(0.80)  LDD0794  [14]
 LDCM0478  CL84 HCT 116 C26(1.51); C370(0.88); C417(0.67); C420(0.67)  LDD0795  [14]
 LDCM0479  CL85 HCT 116 C26(1.20); C370(1.09); C417(0.88); C420(0.88)  LDD0796  [14]
 LDCM0480  CL86 HCT 116 C26(1.05); C370(1.17); C417(0.95); C420(0.95)  LDD0797  [14]
 LDCM0481  CL87 HCT 116 C26(1.26); C370(1.06); C417(0.87); C420(0.87)  LDD0798  [14]
 LDCM0482  CL88 HCT 116 C26(1.41); C370(1.10); C417(0.93); C420(0.93)  LDD0799  [14]
 LDCM0483  CL89 HCT 116 C26(1.87); C370(0.83); C417(0.63); C420(0.63)  LDD0800  [14]
 LDCM0484  CL9 HCT 116 C26(0.98); C370(0.97); C417(1.06); C420(1.06)  LDD0801  [14]
 LDCM0485  CL90 HCT 116 C26(0.88); C370(1.08); C417(0.80); C420(0.80)  LDD0802  [14]
 LDCM0486  CL91 HCT 116 C26(1.02); C370(0.89); C417(0.87); C420(0.87)  LDD0803  [14]
 LDCM0487  CL92 HCT 116 C26(0.98); C370(0.88); C417(0.85); C420(0.85)  LDD0804  [14]
 LDCM0488  CL93 HCT 116 C26(0.99); C370(0.96); C417(0.88); C420(0.88)  LDD0805  [14]
 LDCM0489  CL94 HCT 116 C26(1.01); C370(0.92); C417(0.78); C420(0.78)  LDD0806  [14]
 LDCM0490  CL95 HCT 116 C26(1.01); C370(0.84); C417(0.84); C420(0.84)  LDD0807  [14]
 LDCM0491  CL96 HCT 116 C26(1.05); C370(0.96); C417(0.94); C420(0.94)  LDD0808  [14]
 LDCM0492  CL97 HCT 116 C26(1.02); C370(0.98); C417(1.03); C420(1.03)  LDD0809  [14]
 LDCM0493  CL98 HCT 116 C26(1.06); C370(0.92); C417(0.95); C420(0.95)  LDD0810  [14]
 LDCM0494  CL99 HCT 116 C26(1.17); C370(1.03); C417(0.89); C420(0.89)  LDD0811  [14]
 LDCM0634  CY-0357 Hep-G2 C461(0.99)  LDD2228  [21]
 LDCM0017  DFG-out-2 A431 12.50  LDD0075  [36]
 LDCM0495  E2913 HEK-293T C62(0.83); C471(1.01); C370(0.85); C461(0.96)  LDD1698  [40]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C461(1.33); C403(0.89); C26(0.88)  LDD1702  [6]
 LDCM0625  F8 Ramos C62(1.50); C461(0.92); C26(0.41); C339(0.63)  LDD2187  [41]
 LDCM0572  Fragment10 Ramos C62(0.79); C461(0.75); C26(0.93); C339(0.62)  LDD2189  [41]
 LDCM0573  Fragment11 Ramos C62(0.20); C461(0.28); C26(1.29); C339(5.41)  LDD2190  [41]
 LDCM0574  Fragment12 Ramos C62(1.51); C461(0.67); C26(0.55); C339(0.62)  LDD2191  [41]
 LDCM0575  Fragment13 Ramos C62(1.16); C461(0.97); C26(1.23)  LDD2192  [41]
 LDCM0576  Fragment14 Ramos C62(0.69); C461(0.45); C26(0.99); C339(0.74)  LDD2193  [41]
 LDCM0579  Fragment20 Ramos C62(0.93); C461(0.56); C26(0.86); C339(0.73)  LDD2194  [41]
 LDCM0580  Fragment21 Ramos C62(1.09); C461(1.04); C26(0.44)  LDD2195  [41]
 LDCM0582  Fragment23 Ramos C62(1.74); C461(1.07); C26(1.31)  LDD2196  [41]
 LDCM0578  Fragment27 Ramos C62(1.25); C461(1.07); C26(1.08)  LDD2197  [41]
 LDCM0586  Fragment28 Ramos C62(0.44); C461(0.74); C26(0.41)  LDD2198  [41]
 LDCM0588  Fragment30 Ramos C62(2.21); C461(1.34); C26(1.65); C339(1.89)  LDD2199  [41]
 LDCM0589  Fragment31 Ramos C62(1.85); C461(1.03); C26(0.98)  LDD2200  [41]
 LDCM0590  Fragment32 Ramos C62(1.38); C461(1.32); C26(1.06); C339(0.95)  LDD2201  [41]
 LDCM0468  Fragment33 HCT 116 C26(1.12); C370(1.02); C417(0.80); C420(0.80)  LDD0785  [14]
 LDCM0596  Fragment38 Ramos C62(1.69); C461(0.92); C26(1.23)  LDD2203  [41]
 LDCM0566  Fragment4 Ramos C62(0.68); C461(0.54); C26(0.36); C339(0.55)  LDD2184  [41]
 LDCM0427  Fragment51 HCT 116 C370(0.88); C417(1.08); C420(0.73); C461(1.24)  LDD0744  [14]
 LDCM0610  Fragment52 Ramos C62(1.83); C461(1.11); C26(1.12)  LDD2204  [41]
 LDCM0614  Fragment56 Ramos C62(4.41); C461(1.44); C26(1.04); C339(1.10)  LDD2205  [41]
 LDCM0569  Fragment7 Ramos C62(0.74); C461(0.50); C26(0.37); C339(0.42)  LDD2186  [41]
 LDCM0571  Fragment9 Ramos C62(0.64); C461(0.77); C26(1.29); C339(0.47)  LDD2188  [41]
 LDCM0116  HHS-0101 DM93 Y261(0.76); Y269(0.83); Y476(0.87); Y296(0.92)  LDD0264  [12]
 LDCM0117  HHS-0201 DM93 Y58(0.70); Y269(0.72); Y476(0.80); Y296(0.81)  LDD0265  [12]
 LDCM0118  HHS-0301 DM93 Y58(0.78); Y296(0.79); Y48(0.81); Y476(0.85)  LDD0266  [12]
 LDCM0119  HHS-0401 DM93 Y296(0.84); Y269(0.84); Y58(0.84); Y48(0.86)  LDD0267  [12]
 LDCM0120  HHS-0701 DM93 Y58(0.85); Y296(0.88); Y48(0.91); Y261(0.94)  LDD0268  [12]
 LDCM0107  IAA HeLa C26(0.00); H101(0.00); H382(0.00); H521(0.00)  LDD0221  [31]
 LDCM0123  JWB131 DM93 Y236(0.79); Y27(2.42); Y310(1.24); Y316(1.09)  LDD0285  [11]
 LDCM0124  JWB142 DM93 Y236(0.50); Y27(0.13); Y310(0.59); Y316(1.81)  LDD0286  [11]
 LDCM0125  JWB146 DM93 Y236(0.65); Y27(0.27); Y310(0.96); Y316(0.61)  LDD0287  [11]
 LDCM0126  JWB150 DM93 Y236(7.45); Y27(2.88); Y310(3.86); Y316(2.95)  LDD0288  [11]
 LDCM0127  JWB152 DM93 Y236(1.73); Y27(0.71); Y310(2.13); Y316(1.69)  LDD0289  [11]
 LDCM0128  JWB198 DM93 Y236(0.77); Y27(0.43); Y310(0.80); Y316(0.15)  LDD0290  [11]
 LDCM0129  JWB202 DM93 Y236(0.46); Y27(0.15); Y310(0.36); Y316(0.89)  LDD0291  [11]
 LDCM0130  JWB211 DM93 Y236(0.55); Y310(0.81); Y316(0.37); Y354(0.99)  LDD0292  [11]
 LDCM0022  KB02 HCT 116 C417(1.75); C420(1.75); C471(1.72); C26(1.13)  LDD0080  [14]
 LDCM0023  KB03 HCT 116 C417(2.41); C420(2.41); C471(1.83); C26(1.23)  LDD0081  [14]
 LDCM0024  KB05 HCT 116 C417(1.65); C420(1.65); C471(1.29); C26(1.06)  LDD0082  [14]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C370(1.12); C403(1.99); C62(0.90); C461(0.86)  LDD2102  [6]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C403(0.64); C461(0.88); C339(0.66)  LDD2121  [6]
 LDCM0109  NEM HeLa H101(0.00); H382(0.00); H479(0.00); H521(0.00)  LDD0223  [31]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C339(0.57)  LDD2089  [6]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C370(1.29); C62(1.09); C461(1.14); C278(1.39)  LDD2090  [6]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C370(1.30); C62(0.92); C461(0.95); C339(1.37)  LDD2092  [6]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C370(1.17); C403(1.20); C62(0.98); C461(0.67)  LDD2093  [6]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C62(1.21); C461(1.57); C339(2.15); C278(4.54)  LDD2094  [6]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C370(0.11); C339(0.90); C278(0.28)  LDD2096  [6]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C403(0.73); C62(0.75); C461(0.84); C339(0.85)  LDD2097  [6]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C370(0.63); C403(0.50); C62(0.57); C461(0.42)  LDD2098  [6]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C403(0.84); C62(1.21); C339(0.67); C278(0.71)  LDD2099  [6]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C370(0.42); C461(0.55); C339(0.41); C278(0.48)  LDD2100  [6]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C370(1.08); C403(1.63); C62(1.44); C339(1.01)  LDD2101  [6]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C370(0.48); C461(0.59); C339(0.38); C278(0.32)  LDD2104  [6]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C403(2.83); C62(0.95); C461(1.31); C339(1.71)  LDD2105  [6]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C370(0.36); C62(0.46); C461(0.59); C278(0.44)  LDD2106  [6]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C370(0.60); C403(1.02); C62(0.89); C461(0.75)  LDD2107  [6]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C370(0.63); C62(0.44); C461(0.64); C339(0.61)  LDD2108  [6]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C370(0.63); C403(0.68); C62(0.81); C339(0.82)  LDD2109  [6]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C370(0.44); C62(1.01); C461(1.35); C339(0.46)  LDD2110  [6]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C62(1.16); C461(1.10); C339(0.55); C278(0.66)  LDD2111  [6]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C370(0.47); C461(0.87); C339(0.41); C278(0.34)  LDD2114  [6]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C370(0.55); C403(0.83); C62(0.51); C461(0.57)  LDD2115  [6]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C370(0.26); C339(1.06); C278(0.56)  LDD2116  [6]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C370(0.17); C403(0.12); C339(1.44); C278(0.60)  LDD2118  [6]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C403(5.39); C62(2.63); C339(2.81); C278(1.97)  LDD2119  [6]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C370(0.65); C403(0.83); C62(0.89); C461(0.90)  LDD2120  [6]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C370(0.20); C403(0.08); C339(1.18); C278(0.40)  LDD2122  [6]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C62(0.53); C278(0.48)  LDD2123  [6]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C370(0.17); C339(1.13); C278(0.37)  LDD2124  [6]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C403(0.68); C62(1.04); C339(0.50)  LDD2125  [6]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C370(0.17); C339(1.19); C278(0.38)  LDD2126  [6]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C370(0.65); C403(0.77); C62(0.99); C339(0.61)  LDD2127  [6]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C370(0.79); C403(0.84); C62(0.84); C339(1.01)  LDD2128  [6]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C370(1.29); C403(1.07); C62(1.01); C461(0.92)  LDD2129  [6]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C370(0.62); C403(1.02); C62(0.48); C461(0.42)  LDD2133  [6]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C370(0.43); C403(0.66); C62(0.42); C339(0.55)  LDD2134  [6]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C370(0.91); C62(0.97); C461(0.87); C339(0.76)  LDD2135  [6]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C403(0.98); C62(0.91); C461(0.87); C339(0.54)  LDD2136  [6]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C403(0.79); C62(0.99); C339(0.68); C278(0.81)  LDD2137  [6]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C62(1.27); C278(0.89); C461(0.85); C403(0.82)  LDD1700  [6]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C370(0.61); C62(0.80); C461(0.71); C339(0.38)  LDD2140  [6]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C370(0.94); C62(0.54); C461(0.58); C339(0.84)  LDD2141  [6]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C403(1.00); C62(1.03); C339(1.40); C278(0.61)  LDD2143  [6]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C370(3.92); C403(5.51); C339(4.40); C278(0.98)  LDD2144  [6]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C370(2.53); C62(1.04); C461(2.89); C339(1.45)  LDD2145  [6]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C370(1.05); C403(0.87); C62(1.06); C339(0.68)  LDD2146  [6]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C370(2.27); C403(2.77); C62(3.56); C339(5.28)  LDD2147  [6]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C370(0.40); C62(0.47); C461(0.39); C339(0.45)  LDD2148  [6]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C370(0.20); C403(0.06); C339(1.19); C278(0.36)  LDD2149  [6]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C339(0.68)  LDD2150  [6]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C370(0.16); C403(0.08); C339(1.08); C278(0.35)  LDD2151  [6]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C370(1.72); C62(1.38); C461(1.09); C278(2.65)  LDD2153  [6]
 LDCM0628  OTUB2-COV-1 HEK-293T C461(0.63)  LDD2207  [42]
 LDCM0131  RA190 MM1.R C26(1.23); C461(1.13)  LDD0304  [43]
 LDCM0021  THZ1 HCT 116 C62(1.25); C370(1.04); C471(1.06)  LDD2173  [14]
 LDCM0110  W12 Hep-G2 K530(0.82); Q529(0.82); Q532(0.83); C461(6.19)  LDD0237  [32]
 LDCM0111  W14 Hep-G2 K530(1.19); C461(8.48)  LDD0238  [32]
 LDCM0112  W16 Hep-G2 Q529(1.04); Q532(1.07); K530(1.10); C461(1.49)  LDD0239  [32]
 LDCM0113  W17 Hep-G2 K530(1.23); Q532(1.23)  LDD0240  [32]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Phosphatidate cytidylyltransferase 2 (CDS2) CDS family O95674
DNA polymerase alpha subunit B (POLA2) DNA polymerase alpha subunit B family Q14181
Serine/threonine-protein phosphatase 5 (PPP5C) PPP phosphatase family P53041
Epidermal growth factor receptor (EGFR) Tyr protein kinase family P00533
Receptor tyrosine-protein kinase erbB-2 (ERBB2) Tyr protein kinase family P04626
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Heat shock protein HSP 90-beta (HSP90AB1) Heat shock protein 90 family P08238
Cellular tumor antigen p53 (TP53) P53 family P04637
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Forkhead box protein D4-like 6 (FOXD4L6) . Q3SYB3
Myc proto-oncogene protein (MYC) . P01106
Other
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hsp90 co-chaperone Cdc37-like 1 (CDC37L1) CDC37 family Q7L3B6
Protein FAM9A (FAM9A) FAM9 family Q8IZU1
Protein sprouty homolog 4 (SPRY4) Sprouty family Q9C004
TNF receptor-associated factor 5 (TRAF5) TNF receptor-associated factor family O00463
Echinoderm microtubule-associated protein-like 1 (EML1) WD repeat EMAP family O00423
Histone-binding protein RBBP4 (RBBP4) WD repeat RBAP46/RBAP48/MSI1 family Q09028
Adrenocortical dysplasia protein homolog (ACD) . Q96AP0
Coiled-coil domain-containing protein 117 (CCDC117) . Q8IWD4
Uncharacterized protein C3orf36 (C3orf36) . Q3SXR2

The Drug(s) Related To This Target

Approved
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Copper . DB09130

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Comparison of Different Competitive Proteome Profiling Approaches in Target Identification of Covalent Inhibitors. Chembiochem. 2022 Dec 16;23(24):e202200389. doi: 10.1002/cbic.202200389. Epub 2022 Nov 22.
3 2-Ethynylbenzaldehyde-Based, Lysine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Nonkinases. J Am Chem Soc. 2023 Feb 12. doi: 10.1021/jacs.2c11595. Online ahead of print.
Mass spectrometry data entry: PXD037665
4 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
5 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
6 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
7 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells. J Am Chem Soc. 2020 Apr 1;142(13):6051-6059. doi: 10.1021/jacs.9b12116. Epub 2020 Mar 23.
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Mass spectrometry data entry: PXD028270
9 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
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Mass spectrometry data entry: PXD044625
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15 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
16 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
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Mass spectrometry data entry: PXD028853
18 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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Mass spectrometry data entry: PXD029500 , PXD031647
20 Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer. J Proteome Res. 2018 Jan 5;17(1):63-75. doi: 10.1021/acs.jproteome.7b00329. Epub 2017 Nov 22.
Mass spectrometry data entry: PXD006095 , PXD006096
21 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
22 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
23 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD022279
26 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
27 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
28 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
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Mass spectrometry data entry: PXD033004
30 Oxidative cyclization reagents reveal tryptophan cation- interactions. Nature. 2024 Mar;627(8004):680-687. doi: 10.1038/s41586-024-07140-6. Epub 2024 Mar 6.
Mass spectrometry data entry: PXD001377 , PXD005252
31 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
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Mass spectrometry data entry: PXD044402
41 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
42 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.
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