Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0130
Competitor Name
JWB211
Synonyms
SCHEMBL22558904
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 321.4
Lipid-water partition coefficient (xlogp) 2.6
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C13H11N3O3S2
IUPAC Name
1-(4-methoxyphenyl)sulfonyl-3-thiophen-2-yl-1,2,4-triazole
Canonical SMILES
COC1=CC=C(C=C1)S(=O)(=O)N2C=NC(=N2)C3=CC=CS3
InChI
InChI=1S/C13H11N3O3S2/c1-19-10-4-6-11(7-5-10)21(17,18)16-9-14-13(15-16)12-3-2-8-20-12/h2-9H,1H3
InChIKey
NPLQXHMWVIWQHQ-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
HHS-482
 Probe Info  		50 uM Human melanoma cell lysate (DM93) [1]

Target(s) List of this Competitor

300 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8) LDTP09770 1.07  LDD0292 
1,4-alpha-glucan-branching enzyme (GBE1) LDTP05419 1.10  LDD0292 
14 kDa phosphohistidine phosphatase (PHPT1) LDTP12543 1.36; 0.92  LDD0292 
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 1.12  LDD0292 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 0.29  LDD0292 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 0.94  LDD0292 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 1.14  LDD0292 
26S proteasome non-ATPase regulatory subunit 5 (PSMD5) LDTP06532 2.44  LDD0292 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 0.84  LDD0292 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 1.15  LDD0292 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 5.06; 3.49  LDD0292 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 0.10  LDD0292 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 0.92  LDD0292 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 5.64  LDD0292 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 0.91  LDD0292 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 0.41  LDD0292 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.59; 1.66; 1.03 ...  LDD0292 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 0.95  LDD0292 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 0.65  LDD0292 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 0.62  LDD0292 
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) LDTP12463 0.47  LDD0292 
Actin, alpha cardiac muscle 1 (ACTC1) LDTP05069 0.80  LDD0292 
Actin, cytoplasmic 1 (ACTB) LDTP04876 0.77; 0.94; 0.70 ...  LDD0292 
Acylamino-acid-releasing enzyme (APEH) LDTP02693 0.33  LDD0292 
Adenosylhomocysteinase (AHCY) LDTP03242 0.78; 1.01  LDD0292 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 0.92  LDD0292 
ADP-ribose pyrophosphatase, mitochondrial (NUDT9) LDTP11318 0.97  LDD0292 
ADP-ribosylation factor 1 (ARF1) LDTP05192 1.06; 1.40  LDD0292 
ADP-ribosylation factor 3 (ARF3) LDTP04907 1.06; 1.40  LDD0292 
ADP-ribosylation factor 4 (ARF4) LDTP02942 1.06; 1.40  LDD0292 
ADP-ribosylation factor 5 (ARF5) LDTP05193 1.06; 1.40  LDD0292 
ADP-sugar pyrophosphatase (NUDT5) LDTP13462 1.48  LDD0292 
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) LDTP00776 0.84; 0.92; 0.86 ...  LDD0292 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 0.76; 0.36  LDD0292 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 0.33; 0.97  LDD0292 
Aldo-keto reductase family 1 member A1 (AKR1A1) LDTP02729 1.29  LDD0292 
Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) LDTP13186 0.61; 0.21; 1.20  LDD0292 
Alpha-enolase (ENO1) LDTP02159 0.68; 0.53; 1.83 ...  LDD0292 
Amidophosphoribosyltransferase (PPAT) LDTP05480 0.94  LDD0292 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.05; 1.09  LDD0292 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 2.10; 0.83  LDD0292 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 1.32; 1.27; 0.05 ...  LDD0292 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 4.78; 0.95; 0.44  LDD0292 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 0.84; 1.02; 1.22  LDD0292 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 1.00; 1.69  LDD0292 
ATP-citrate synthase (ACLY) LDTP04561 1.08; 0.93; 1.06 ...  LDD0292 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 0.88  LDD0292 
ATP-dependent 6-phosphofructokinase, muscle type (PFKM) LDTP02261 1.25  LDD0292 
ATP-dependent RNA helicase A (DHX9) LDTP05550 0.60; 1.01  LDD0292 
ATP-dependent RNA helicase DDX1 (DDX1) LDTP09766 2.02; 0.57  LDD0292 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 1.59  LDD0292 
ATPase MORC2 (MORC2) LDTP14308 1.51  LDD0292 
Aurora kinase B (AURKB) LDTP10346 2.38  LDD0292 
Bifunctional coenzyme A synthase (COASY) LDTP05736 0.84  LDD0292 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 1.10  LDD0292 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 0.89  LDD0292 
Biliverdin reductase A (BLVRA) LDTP04552 0.79  LDD0292 
Biotinidase (BTD) LDTP04030 2.64  LDD0292 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 1.25; 0.79; 1.44 ...  LDD0292 
Calcyclin-binding protein (CACYBP) LDTP12163 1.30; 0.82; 1.45  LDD0292 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 1.85  LDD0292 
Carbonyl reductase [NADPH] 3 (CBR3) LDTP01321 0.86  LDD0292 
Casein kinase II subunit beta (CSNK2B) LDTP05067 0.60  LDD0292 
Catalase (CAT) LDTP02001 1.34  LDD0292 
Cathepsin B (CTSB) LDTP02223 0.87; 0.86; 0.85 ...  LDD0292 
Cathepsin D (CTSD) LDTP02198 1.11; 1.12  LDD0292 
Cathepsin Z (CTSZ) LDTP13147 0.94; 1.57; 1.87 ...  LDD0292 
Citrate synthase, mitochondrial (CS) LDTP01205 1.27; 0.97  LDD0292 
Cleavage and polyadenylation specificity factor subunit 5 (NUDT21) LDTP00873 1.08  LDD0292 
CTP synthase 1 (CTPS1) LDTP02922 1.17; 1.23; 1.01  LDD0292 
Cyclin-dependent kinase 1 (CDK1) LDTP02149 0.83; 1.87; 0.89 ...  LDD0292 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 0.83; 0.89  LDD0292 
Cystathionine gamma-lyase (CTH) LDTP03656 0.70  LDD0292 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 0.77  LDD0292 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 1.00  LDD0292 
Cytoglobin (CYGB) LDTP09656 1.51; 0.98  LDD0292 
Cytosol aminopeptidase (LAP3) LDTP03455 1.52  LDD0292 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 5.00; 0.86  LDD0292 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 2.20  LDD0292 
Dehydrogenase/reductase SDR family member 11 (DHRS11) LDTP07678 0.82  LDD0292 
Dihydropteridine reductase (QDPR) LDTP02342 0.46  LDD0292 
Dihydropyrimidinase-related protein 3 (DPYSL3) LDTP06079 1.01  LDD0292 
Dipeptidyl peptidase 3 (DPP3) LDTP12803 1.00  LDD0292 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 0.96  LDD0292 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 0.92  LDD0292 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 2.78  LDD0292 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 0.92  LDD0292 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 0.07  LDD0292 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 1.02  LDD0292 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 1.38  LDD0292 
Dual specificity protein phosphatase 23 (DUSP23) LDTP11289 0.88  LDD0292 
Dual specificity protein phosphatase 3 (DUSP3) LDTP04415 1.18  LDD0292 
Dynamin-1-like protein (DNM1L) LDTP00273 2.21  LDD0292 
E3 ubiquitin-protein ligase ARIH2 (ARIH2) LDTP01575 1.07  LDD0292 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 1.11  LDD0292 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 0.80  LDD0292 
EH domain-containing protein 4 (EHD4) LDTP11788 0.95  LDD0292 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 1.32; 0.69; 0.84 ...  LDD0292 
Elongation factor 2 (EEF2) LDTP02672 1.13; 0.52; 1.78 ...  LDD0292 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 0.87; 0.79; 0.81 ...  LDD0292 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 6.49; 0.58; 1.02 ...  LDD0292 
Enoyl-CoA hydratase, mitochondrial (ECHS1) LDTP03518 0.98  LDD0292 
ERO1-like protein alpha (ERO1A) LDTP10386 1.63  LDD0292 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 0.61; 1.04; 0.87 ...  LDD0292 
Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 0.92  LDD0292 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 0.98  LDD0292 
Exosome complex exonuclease RRP44 (DIS3) LDTP13887 1.20  LDD0292 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 0.92  LDD0292 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 1.07; 1.03  LDD0292 
Fatty acid synthase (FASN) LDTP04243 1.30; 0.86; 1.39 ...  LDD0292 
Flap endonuclease 1 (FEN1) LDTP03872 0.91  LDD0292 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 0.82  LDD0292 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 0.68; 0.94; 0.65 ...  LDD0292 
Fumarate hydratase, mitochondrial (FH) LDTP02235 0.94  LDD0292 
Fumarylacetoacetase (FAH) LDTP02868 1.50  LDD0292 
Galactokinase (GALK1) LDTP04424 0.98  LDD0292 
Gamma-enolase (ENO2) LDTP02328 0.64; 0.69  LDD0292 
GDP-mannose 4,6 dehydratase (GMDS) LDTP00999 1.03  LDD0292 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 1.07  LDD0292 
Glucosamine-6-phosphate isomerase 1 (GNPDA1) LDTP04113 1.92  LDD0292 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 1.16; 0.97  LDD0292 
Glucose-6-phosphate isomerase (GPI) LDTP02162 0.21; 0.89; 0.49  LDD0292 
Glutaminase kidney isoform, mitochondrial (GLS) LDTP01465 0.41  LDD0292 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 1.08; 1.14  LDD0292 
Glutaredoxin-1 (GLRX) LDTP03786 1.41  LDD0292 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 1.44; 0.65  LDD0292 
Glutathione S-transferase A4 (GSTA4) LDTP00575 4.53  LDD0292 
Glutathione S-transferase kappa 1 (GSTK1) LDTP13900 1.14  LDD0292 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.66  LDD0292 
Glutathione S-transferase P (GSTP1) LDTP02333 0.54; 0.77; 0.63 ...  LDD0292 
Glutathione synthetase (GSS) LDTP04200 1.06; 0.52  LDD0292 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 0.99; 0.89; 0.98 ...  LDD0292 
Glycine--tRNA ligase (GARS1) LDTP03946 0.48; 1.51; 4.06 ...  LDD0292 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.85; 0.90; 1.06 ...  LDD0292 
Glycogen phosphorylase, liver form (PYGL) LDTP02161 0.83  LDD0292 
GTP-binding nuclear protein Ran (RAN) LDTP05007 0.68; 0.72; 0.84 ...  LDD0292 
HBS1-like protein (HBS1L) LDTP14019 0.62  LDD0292 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 1.18; 0.75; 0.91 ...  LDD0292 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.85; 0.51; 0.60 ...  LDD0292 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 0.93  LDD0292 
Histone deacetylase 1 (HDAC1) LDTP05918 0.89  LDD0292 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 0.93  LDD0292 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 0.94  LDD0292 
Inorganic pyrophosphatase (PPA1) LDTP14854 0.78; 8.68; 1.01  LDD0292 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 1.01  LDD0292 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 1.07; 0.85; 0.90 ...  LDD0292 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 1.45  LDD0292 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 0.82; 0.94; 0.58  LDD0292 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 0.05  LDD0292 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 0.90  LDD0292 
Kynurenine--oxoglutarate transaminase 3 (KYAT3) LDTP07763 0.39  LDD0292 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 0.92; 1.09; 0.94 ...  LDD0292 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 0.83; 0.88; 0.97 ...  LDD0292 
L-xylulose reductase (DCXR) LDTP08082 1.74  LDD0292 
Lactoylglutathione lyase (GLO1) LDTP05434 1.36  LDD0292 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 0.83  LDD0292 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 1.04; 1.03; 4.34  LDD0292 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 1.25; 1.04; 0.90  LDD0292 
Lysosomal protective protein (CTSA) LDTP02505 0.85  LDD0292 
Macrophage migration inhibitory factor (MIF) LDTP02713 0.71; 1.20; 0.57 ...  LDD0292 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.62; 0.87  LDD0292 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 0.62; 0.43; 0.72 ...  LDD0292 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 1.06  LDD0292 
MAP kinase-activated protein kinase 3 (MAPKAPK3) LDTP06589 0.30; 0.82  LDD0292 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 0.64; 0.89; 0.18 ...  LDD0292 
Methionine adenosyltransferase 2 subunit beta (MAT2B) LDTP12915 1.02  LDD0292 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 1.07  LDD0292 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 1.93  LDD0292 
Methylmalonyl-CoA mutase, mitochondrial (MMUT) LDTP03150 1.23  LDD0292 
Methylthioribulose-1-phosphate dehydratase (APIP) LDTP10368 2.18  LDD0292 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 0.18  LDD0292 
Mitogen-activated protein kinase 1 (MAPK1) LDTP03445 1.32; 1.85  LDD0292 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 0.85; 0.84  LDD0292 
Myosin-10 (MYH10) LDTP03765 0.90; 1.50; 0.93 ...  LDD0292 
Myosin-9 (MYH9) LDTP03764 0.90; 1.67; 0.49 ...  LDD0292 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 0.92  LDD0292 
NAD(P)H dehydrogenase [quinone] 1 (NQO1) LDTP02798 5.24; 1.20; 2.07  LDD0292 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 0.82  LDD0292 
NEDD8-activating enzyme E1 regulatory subunit (NAE1) LDTP05925 1.08  LDD0292 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 0.47  LDD0292 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 0.79; 0.57  LDD0292 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 2.56  LDD0292 
Nucleoside diphosphate kinase B (NME2) LDTP03169 0.60  LDD0292 
Omega-amidase NIT2 (NIT2) LDTP12428 0.55; 1.15; 0.59 ...  LDD0292 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 2.47; 3.65; 4.58  LDD0292 
Palmitoyltransferase ZDHHC17 (ZDHHC17) LDTP08456 0.26  LDD0292 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 1.13; 0.92  LDD0292 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 0.89  LDD0292 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 0.81; 0.81  LDD0292 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 1.02; 1.78; 0.80  LDD0292 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 1.13  LDD0292 
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) LDTP11823 0.97  LDD0292 
Peroxiredoxin-1 (PRDX1) LDTP05503 0.99; 1.54; 0.96  LDD0292 
Peroxiredoxin-4 (PRDX4) LDTP05773 1.52; 1.19  LDD0292 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 0.65  LDD0292 
Phosphatidylinositide phosphatase SAC2 (INPP5F) LDTP13867 0.94  LDD0292 
Phosphoglucomutase-1 (PGM1) LDTP03818 2.00  LDD0292 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 1.07; 0.96; 1.23 ...  LDD0292 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 1.00; 1.84; 0.90 ...  LDD0292 
Phosphoserine aminotransferase (PSAT1) LDTP14198 0.72; 0.74; 0.22 ...  LDD0292 
Poly(A) polymerase alpha (PAPOLA) LDTP04394 0.88  LDD0292 
Probable 18S rRNA (guanine-N(7))-methyltransferase (BUD23) LDTP00845 1.09  LDD0292 
Probable aminopeptidase NPEPL1 (NPEPL1) LDTP09126 1.52  LDD0292 
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL) LDTP11759 1.03; 0.80  LDD0292 
Prolyl endopeptidase (PREP) LDTP04163 1.07  LDD0292 
Prostaglandin reductase 1 (PTGR1) LDTP06227 0.86; 1.30  LDD0292 
Prostaglandin reductase 2 (PTGR2) LDTP08979 1.25; 3.10; 4.76  LDD0292 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 0.81; 0.63  LDD0292 
Proteasome subunit alpha type-2 (PSMA2) LDTP03331 1.14; 0.95; 1.07  LDD0292 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 0.96; 1.18; 0.87 ...  LDD0292 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 0.91; 1.00; 0.56 ...  LDD0292 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 1.07; 1.18  LDD0292 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 0.77; 0.10  LDD0292 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 0.98; 0.85  LDD0292 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 1.03; 0.77  LDD0292 
Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 0.85  LDD0292 
Protein disulfide-isomerase (P4HB) LDTP02188 1.45; 0.65; 0.92 ...  LDD0292 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.98; 1.12; 0.73 ...  LDD0292 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 1.09; 2.70; 2.52  LDD0292 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 1.22  LDD0292 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 0.81  LDD0292 
Protein kinase C delta type (PRKCD) LDTP05461 1.21  LDD0292 
Protein phosphatase 1G (PPM1G) LDTP00616 20.00  LDD0292 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 0.76  LDD0292 
Putative elongation factor 1-alpha-like 3 (EEF1A1P5) LDTP15029 1.32; 0.69; 0.84 ...  LDD0292 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 1.06  LDD0292 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 0.52; 0.56  LDD0292 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 0.88; 1.14; 0.94 ...  LDD0292 
Pyruvate kinase PKM (PKM) LDTP02733 0.34; 1.16; 0.77 ...  LDD0292 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 0.81; 0.75  LDD0292 
RAC-gamma serine/threonine-protein kinase (AKT3) LDTP13799 0.92; 0.75  LDD0292 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 0.89; 0.94  LDD0292 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 0.54  LDD0292 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 0.97  LDD0292 
RING finger and CHY zinc finger domain-containing protein 1 (RCHY1) LDTP10686 1.01  LDD0292 
RNA demethylase ALKBH5 (ALKBH5) LDTP07547 1.12  LDD0292 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 1.87  LDD0292 
RuvB-like 1 (RUVBL1) LDTP13816 0.58  LDD0292 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 0.81; 0.67  LDD0292 
S-formylglutathione hydrolase (ESD) LDTP02521 0.80; 1.01  LDD0292 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 1.49  LDD0292 
Sepiapterin reductase (SPR) LDTP03730 0.78; 0.85  LDD0292 
Septin-2 (SEPTIN2) LDTP06279 1.15; 1.05  LDD0292 
Septin-7 (SEPTIN7) LDTP06513 0.32; 0.76  LDD0292 
Septin-9 (SEPTIN9) LDTP13272 0.30; 0.55; 1.24 ...  LDD0292 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 0.98  LDD0292 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 0.49  LDD0292 
Serine/threonine-protein kinase PAK 2 (PAK2) LDTP05776 0.91  LDD0292 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 0.76  LDD0292 
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) LDTP05064 0.89  LDD0292 
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) LDTP04998 0.88  LDD0292 
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) LDTP04870 0.89  LDD0292 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 1.35  LDD0292 
Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C) LDTP00333 0.90  LDD0292 
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) LDTP04959 0.89; 0.99  LDD0292 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 0.89; 0.99  LDD0292 
Sialic acid synthase (NANS) LDTP12473 0.60; 0.85; 0.98  LDD0292 
Spermidine synthase (SRM) LDTP03008 0.65  LDD0292 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 0.62  LDD0292 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 0.95; 1.02  LDD0292 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 1.08  LDD0292 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 1.71  LDD0292 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 0.87; 0.63  LDD0292 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 1.12; 0.76; 2.56  LDD0292 
Thimet oligopeptidase (THOP1) LDTP04542 0.78  LDD0292 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 0.89  LDD0292 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 1.12; 1.00; 0.93 ...  LDD0292 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 0.77; 0.44; 0.73 ...  LDD0292 
Thymidylate kinase (DTYMK) LDTP03258 0.82  LDD0292 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 0.89; 1.14; 0.87 ...  LDD0292 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 1.44  LDD0292 
Transketolase (TKT) LDTP03487 1.04; 0.86; 1.10 ...  LDD0292 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 1.07  LDD0292 
Triosephosphate isomerase (TPI1) LDTP04851 0.75; 2.69; 0.42  LDD0292 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 0.94  LDD0292 
Tryptophan--tRNA ligase, cytoplasmic (WARS1) LDTP03222 0.67; 0.58; 0.36 ...  LDD0292 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 0.91; 0.89; 0.90 ...  LDD0292 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 0.91; 0.89; 0.90 ...  LDD0292 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 0.90  LDD0292 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 0.74; 0.05  LDD0292 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 0.77; 1.06  LDD0292 
Tyrosine-protein kinase CSK (CSK) LDTP03944 1.24  LDD0292 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 1.13  LDD0292 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 0.45  LDD0292 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 0.83  LDD0292 
Ubiquitin-conjugating enzyme E2 N (UBE2N) LDTP04900 1.55; 3.93; 1.25  LDD0292 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 1.03; 0.61; 0.88 ...  LDD0292 
UDP-glucose 4-epimerase (GALE) LDTP06111 1.74  LDD0292 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 1.12; 1.29; 1.00 ...  LDD0292 
UMP-CMP kinase (CMPK1) LDTP03519 1.01  LDD0292 
Unconventional myosin-Ie (MYO1E) LDTP05708 5.20  LDD0292 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 0.87  LDD0292 
Uridine phosphorylase 1 (UPP1) LDTP06643 0.63; 0.67; 0.64 ...  LDD0292 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 1.30; 0.84  LDD0292 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 0.94; 0.91; 1.09  LDD0292 
V-type proton ATPase subunit E 2 (ATP6V1E2) LDTP15684 1.02  LDD0292 
Valine--tRNA ligase (VARS1) LDTP03366 0.97; 1.57  LDD0292 
WD repeat-containing protein 82 (WDR82) LDTP07715 1.41  LDD0292 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 0.80; 1.33  LDD0292 
Xaa-Pro dipeptidase (PEPD) LDTP02639 1.58  LDD0292 
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⏷ Show the Full List of 300 Enzyme
42 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 0.93; 1.00; 0.75 ...  LDD0292 
14-3-3 protein gamma (YWHAG) LDTP04953 0.77  LDD0292 
14-3-3 protein theta (YWHAQ) LDTP03385 0.87; 0.27  LDD0292 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.54; 0.86; 2.27 ...  LDD0292 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 0.94; 1.06  LDD0292 
Alpha-crystallin B chain (CRYAB) LDTP01929 1.77  LDD0292 
Alpha-synuclein (SNCA) LDTP03848 2.77  LDD0292 
Annexin A2 (ANXA2) LDTP02199 0.44; 0.98; 0.32 ...  LDD0292 
Annexin A5 (ANXA5) LDTP02307 0.61; 0.92; 0.78 ...  LDD0292 
Annexin A6 (ANXA6) LDTP02247 0.75; 1.48  LDD0292 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 1.69  LDD0292 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 1.00; 0.95  LDD0292 
Calreticulin (CALR) LDTP03402 0.92; 0.77; 1.12 ...  LDD0292 
Cation-independent mannose-6-phosphate receptor (IGF2R) LDTP02586 1.25  LDD0292 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 1.11; 0.56; 0.72 ...  LDD0292 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 0.92; 0.44; 0.84  LDD0292 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.31; 1.16  LDD0292 
Copine-3 (CPNE3) LDTP01133 1.05; 1.19  LDD0292 
Cystatin-B (CSTB) LDTP02009 0.89; 0.81; 1.07  LDD0292 
Dihydropyrimidinase-related protein 2 (DPYSL2) LDTP06554 1.79; 1.01; 0.69 ...  LDD0292 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 1.38; 1.42  LDD0292 
Exportin-1 (XPO1) LDTP00501 0.88; 3.01  LDD0292 
Filamin-A (FLNA) LDTP03107 1.28; 1.20  LDD0292 
Galectin-3 (LGALS3) LDTP02929 0.72  LDD0292 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 0.72; 0.68; 1.12 ...  LDD0292 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 0.69  LDD0292 
Importin subunit beta-1 (KPNB1) LDTP06242 0.92  LDD0292 
mRNA export factor RAE1 (RAE1) LDTP05122 1.02  LDD0292 
Protein SEC13 homolog (SEC13) LDTP04707 1.23  LDD0292 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 1.11; 0.55  LDD0292 
Sorting nexin-2 (SNX2) LDTP01043 0.21  LDD0292 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.65; 1.00; 0.90 ...  LDD0292 
Talin-1 (TLN1) LDTP14031 0.85; 0.61; 0.85 ...  LDD0292 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 0.44; 0.72; 0.60  LDD0292 
Transferrin receptor protein 1 (TFRC) LDTP01969 1.23  LDD0292 
Ubiquilin-4 (UBQLN4) LDTP12533 0.94  LDD0292 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 0.82  LDD0292 
V-type proton ATPase subunit C 1 (ATP6V1C1) LDTP03105 0.75  LDD0292 
V-type proton ATPase subunit E 1 (ATP6V1E1) LDTP03811 1.02  LDD0292 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 0.88  LDD0292 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 0.86  LDD0292 
Voltage-gated potassium channel subunit beta-2 (KCNAB2) LDTP05817 1.11  LDD0292 
------------------------------------------------------------------------------------
⏷ Show the Full List of 42 Transporter and channel
9 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Forkhead box protein K1 (FOXK1) LDTP05201 1.39  LDD0292 
High mobility group protein B1 (HMGB1) LDTP02343 0.97; 0.34; 0.44 ...  LDD0292 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 1.15  LDD0292 
Nascent polypeptide-associated complex subunit alpha, muscle-specific form (NACA) LDTP14411 0.18  LDD0292 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 2.51  LDD0292 
Signal transducer and activator of transcription 5A (STAT5A) LDTP03971 1.22  LDD0292 
Transcription factor SOX-10 (SOX10) LDTP04752 0.52; 0.85  LDD0292 
Transcription factor SOX-9 (SOX9) LDTP04179 0.96  LDD0292 
Y-box-binding protein 1 (YBX1) LDTP05065 1.67; 1.51; 1.11  LDD0292 
------------------------------------------------------------------------------------
⏷ Show the Full List of 9 Transcription factor
280 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
10 kDa heat shock protein, mitochondrial (HSPE1) LDTP04931 2.52  LDD0292 
14-3-3 protein beta/alpha (YWHAB) LDTP03617 0.88; 0.69  LDD0292 
14-3-3 protein eta (YWHAH) LDTP05442 0.27  LDD0292 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 0.68  LDD0292 
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 0.79  LDD0292 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 3.02  LDD0292 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 0.49  LDD0292 
Actin nucleation-promoting factor WASL (WASL) LDTP00263 2.04  LDD0292 
Actin-related protein 3 (ACTR3) LDTP04902 1.07; 1.11; 0.85 ...  LDD0292 
Adapter molecule crk (CRK) LDTP04091 1.28; 0.99; 1.12  LDD0292 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 0.58; 0.87; 1.16  LDD0292 
AH receptor-interacting protein (AIP) LDTP00202 1.05  LDD0292 
Alpha-actinin-1 (ACTN1) LDTP02631 1.71; 0.67; 2.03  LDD0292 
Alpha-centractin (ACTR1A) LDTP04904 0.76  LDD0292 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 0.70  LDD0292 
Anamorsin (CIAPIN1) LDTP07385 0.69  LDD0292 
Ankyrin repeat and MYND domain-containing protein 2 (ANKMY2) LDTP17620 1.40  LDD0292 
Ankyrin repeat domain-containing protein 39 (ANKRD39) LDTP19320 1.01  LDD0292 
Annexin A3 (ANXA3) LDTP02620 1.10  LDD0292 
Annexin A7 (ANXA7) LDTP03030 0.89  LDD0292 
Apoptosis inhibitor 5 (API5) LDTP11575 1.04  LDD0292 
Beta-parvin (PARVB) LDTP12184 0.69  LDD0292 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 1.45; 0.87; 1.18 ...  LDD0292 
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) LDTP14237 0.71  LDD0292 
C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) LDTP00934 0.64; 0.83  LDD0292 
Calpain small subunit 1 (CAPNS1) LDTP02047 1.17  LDD0292 
Calponin-3 (CNN3) LDTP06383 0.93; 0.87; 1.00 ...  LDD0292 
Calumenin (CALU) LDTP00887 0.86; 0.68; 0.91 ...  LDD0292 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 0.05  LDD0292 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 1.00; 1.20; 1.15 ...  LDD0292 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 0.70  LDD0292 
Coatomer subunit alpha (COPA) LDTP04571 0.86  LDD0292 
Coatomer subunit beta (COPB1) LDTP04570 0.89  LDD0292 
Coatomer subunit gamma-1 (COPG1) LDTP14216 1.35  LDD0292 
Cofilin-1 (CFL1) LDTP03244 1.10; 1.13; 0.75 ...  LDD0292 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 1.49  LDD0292 
Condensin complex subunit 2 (NCAPH) LDTP06268 0.91  LDD0292 
Copper transport protein ATOX1 (ATOX1) LDTP00229 1.31  LDD0292 
Coronin-1B (CORO1B) LDTP11101 1.07  LDD0292 
Coronin-1C (CORO1C) LDTP13580 0.77  LDD0292 
Crk-like protein (CRKL) LDTP04092 1.10; 0.90; 0.99  LDD0292 
Cysteine and glycine-rich protein 1 (CSRP1) LDTP03106 1.36; 0.70; 1.16  LDD0292 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 1.12; 0.56; 1.02 ...  LDD0292 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 1.05  LDD0292 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 0.93  LDD0292 
Destrin (DSTN) LDTP04887 0.80; 0.23  LDD0292 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 4.01  LDD0292 
DnaJ homolog subfamily B member 1 (DNAJB1) LDTP03325 0.84  LDD0292 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 1.30  LDD0292 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 1.73  LDD0292 
Drebrin-like protein (DBNL) LDTP13399 1.10; 1.12; 1.03  LDD0292 
Dynactin subunit 1 (DCTN1) LDTP06082 0.58  LDD0292 
Dynactin subunit 2 (DCTN2) LDTP05922 1.04  LDD0292 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 1.14  LDD0292 
Dynein light chain 2, cytoplasmic (DYNLL2) LDTP10308 1.19  LDD0292 
Elongation factor 1-beta (EEF1B2) LDTP03283 0.97; 0.57; 1.04 ...  LDD0292 
Elongation factor 1-delta (EEF1D) LDTP03499 0.93; 1.19; 0.85 ...  LDD0292 
Elongation factor 1-gamma (EEF1G) LDTP03367 0.82; 0.66; 0.94  LDD0292 
Endoplasmic reticulum resident protein 29 (ERP29) LDTP03509 0.95; 1.36; 8.67  LDD0292 
Endoplasmin (HSP90B1) LDTP02734 0.77; 1.10; 0.96 ...  LDD0292 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 1.12  LDD0292 
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) LDTP13097 1.23  LDD0292 
Eukaryotic translation initiation factor 1 (EIF1) LDTP03953 1.51  LDD0292 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 1.02  LDD0292 
Eukaryotic translation initiation factor 1b (EIF1B) LDTP16815 1.51  LDD0292 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 0.94  LDD0292 
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 1.21  LDD0292 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 0.93  LDD0292 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 0.95  LDD0292 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 1.08  LDD0292 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 0.87  LDD0292 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 0.82; 0.83  LDD0292 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 0.96  LDD0292 
Eukaryotic translation initiation factor 4H (EIF4H) LDTP06301 0.36  LDD0292 
F-actin-uncapping protein LRRC16A (CARMIL1) LDTP07261 0.97  LDD0292 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 1.32; 1.14  LDD0292 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 0.98; 1.01; 0.89 ...  LDD0292 
Gelsolin (GSN) LDTP02145 0.90; 0.93; 0.61 ...  LDD0292 
General transcription factor IIF subunit 2 (GTF2F2) LDTP02703 0.91; 0.89  LDD0292 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 2.09  LDD0292 
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) LDTP06255 1.08  LDD0292 
Heat shock 70 kDa protein 1A (HSPA1A) LDTP02434 1.19; 0.74; 0.78 ...  LDD0292 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.75; 0.86; 1.09 ...  LDD0292 
Heat shock 70 kDa protein 4L (HSPA4L) LDTP14545 4.24  LDD0292 
Heat shock protein 105 kDa (HSPH1) LDTP09811 0.89; 0.74  LDD0292 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 1.23  LDD0292 
Heat shock protein beta-1 (HSPB1) LDTP02053 0.96; 0.83; 0.73 ...  LDD0292 
Heme-binding protein 1 (HEBP1) LDTP16078 1.18; 1.05  LDD0292 
Hepatoma-derived growth factor (HDGF) LDTP04483 0.65  LDD0292 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 0.83; 0.73  LDD0292 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 0.97; 1.00; 0.92 ...  LDD0292 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 0.89; 0.86; 1.00  LDD0292 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 1.00  LDD0292 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 1.10; 0.92; 0.99 ...  LDD0292 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 1.20; 1.65; 0.90 ...  LDD0292 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 0.86; 1.52; 0.91 ...  LDD0292 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 0.50  LDD0292 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 0.66  LDD0292 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 0.78; 0.91; 0.61 ...  LDD0292 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 0.77; 0.86; 1.21 ...  LDD0292 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 0.94  LDD0292 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 1.00; 0.88; 0.98 ...  LDD0292 
Histone H2B type 1-D (H2BC5) LDTP04822 0.20; 0.57; 0.72 ...  LDD0292 
Histone H2B type 1-L (H2BC13) LDTP11001 2.02  LDD0292 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 2.06; 1.07  LDD0292 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 0.81; 0.88  LDD0292 
Hsc70-interacting protein (ST13) LDTP04367 0.76; 0.72  LDD0292 
Influenza virus NS1A-binding protein (IVNS1ABP) LDTP14309 0.98  LDD0292 
Integrator complex subunit 10 (INTS10) LDTP16111 1.01  LDD0292 
IST1 homolog (IST1) LDTP04593 1.17  LDD0292 
Kinesin light chain 1 (KLC1) LDTP05533 1.04; 0.78  LDD0292 
Kinesin light chain 2 (KLC2) LDTP11695 1.04; 0.78  LDD0292 
Laminin subunit beta-2 (LAMB2) LDTP04691 1.06  LDD0292 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 1.05  LDD0292 
Large ribosomal subunit protein eL21 (RPL21) LDTP04107 1.42; 0.45; 0.87  LDD0292 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 0.50; 0.96  LDD0292 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 1.35; 5.76  LDD0292 
Large ribosomal subunit protein eL29 (RPL29) LDTP04140 0.63  LDD0292 
Large ribosomal subunit protein eL31 (RPL31) LDTP05023 2.19  LDD0292 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 1.37; 0.75  LDD0292 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 0.92  LDD0292 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 1.00  LDD0292 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 1.13  LDD0292 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 0.79  LDD0292 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 0.57  LDD0292 
Large ribosomal subunit protein uL13 (RPL13A) LDTP03899 0.91; 0.81  LDD0292 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 0.90  LDD0292 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 1.34  LDD0292 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 0.52  LDD0292 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 0.31  LDD0292 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 0.99  LDD0292 
Large ribosomal subunit protein uL22 (RPL17) LDTP02961 1.13  LDD0292 
Large ribosomal subunit protein uL29 (RPL35) LDTP03999 0.82  LDD0292 
Large ribosomal subunit protein uL30 (RPL7) LDTP02944 0.86  LDD0292 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.33; 0.26; 0.74 ...  LDD0292 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 1.19; 1.12  LDD0292 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 1.26; 0.73  LDD0292 
LRP chaperone MESD (MESD) LDTP06191 0.79  LDD0292 
Macrophage-capping protein (CAPG) LDTP03877 0.39; 1.13  LDD0292 
Microtubule-associated protein 4 (MAP4) LDTP03404 1.00; 0.05  LDD0292 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.46  LDD0292 
Muscleblind-like protein 1 (MBNL1) LDTP12478 1.32; 1.74  LDD0292 
Muscleblind-like protein 2 (MBNL2) LDTP07260 1.32  LDD0292 
Muscleblind-like protein 3 (MBNL3) LDTP12630 1.74  LDD0292 
Myeloid-derived growth factor (MYDGF) LDTP10003 3.24  LDD0292 
Myosin light polypeptide 6 (MYL6) LDTP04875 0.44  LDD0292 
Myosin regulatory light chain 12B (MYL12B) LDTP00487 0.05; 0.62  LDD0292 
Myotrophin (MTPN) LDTP04819 1.06  LDD0292 
N6-adenosine-methyltransferase non-catalytic subunit (METTL14) LDTP12234 1.09  LDD0292 
Nascent polypeptide-associated complex subunit alpha (NACA) LDTP05977 0.18  LDD0292 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 0.90; 0.53  LDD0292 
Nuclear migration protein nudC (NUDC) LDTP13817 0.97  LDD0292 
Nucleolin (NCL) LDTP02990 1.20; 1.08; 1.07 ...  LDD0292 
Nucleolysin TIAR (TIAL1) LDTP05274 1.11  LDD0292 
Nucleophosmin (NPM1) LDTP02164 0.95; 1.26; 0.37  LDD0292 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 0.20; 1.94; 0.83  LDD0292 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 0.68; 0.83; 0.18  LDD0292 
Oxysterol-binding protein-related protein 11 (OSBPL11) LDTP11367 1.72  LDD0292 
Perilipin-3 (PLIN3) LDTP01021 0.87  LDD0292 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 0.47; 1.97; 0.61 ...  LDD0292 
Plastin-3 (PLS3) LDTP02692 0.68; 0.53  LDD0292 
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 1.06; 0.79  LDD0292 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 0.90; 1.04; 1.06  LDD0292 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 1.16; 0.80  LDD0292 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 1.34; 0.88; 0.88 ...  LDD0292 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 0.72; 0.76  LDD0292 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 0.95; 1.03  LDD0292 
Prefoldin subunit 3 (VBP1) LDTP04935 0.94  LDD0292 
Prefoldin subunit 6 (PFDN6) LDTP00573 0.21  LDD0292 
Prelamin-A/C (LMNA) LDTP01932 1.26; 0.96  LDD0292 
Profilin-1 (PFN1) LDTP02218 1.00; 1.03  LDD0292 
Programmed cell death protein 5 (PDCD5) LDTP00417 1.32; 1.97  LDD0292 
Proliferating cell nuclear antigen (PCNA) LDTP02596 0.45; 0.43  LDD0292 
Protein BUD31 homolog (BUD31) LDTP03935 0.69  LDD0292 
Protein FAM118B (FAM118B) LDTP15852 1.41  LDD0292 
Protein flightless-1 homolog (FLII) LDTP05734 0.90  LDD0292 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 0.67; 1.07; 1.17 ...  LDD0292 
Protein mago nashi homolog 2 (MAGOHB) LDTP10071 1.03  LDD0292 
Protein NipSnap homolog 3A (NIPSNAP3A) LDTP18525 2.17; 1.84  LDD0292 
Protein phosphatase 1 regulatory subunit 12A (PPP1R12A) LDTP00495 1.24  LDD0292 
Protein RCC2 (RCC2) LDTP13020 0.98  LDD0292 
Protein S100-A11 (S100A11) LDTP03620 1.16; 1.32  LDD0292 
Protein SET (SET) LDTP05277 1.41  LDD0292 
Protein SGT1 homolog (SUGT1) LDTP13935 0.70; 1.17  LDD0292 
Protein TFG (TFG) LDTP09851 1.28  LDD0292 
Protein transport protein Sec23A (SEC23A) LDTP06390 0.91  LDD0292 
Protein transport protein Sec23B (SEC23B) LDTP06391 0.82  LDD0292 
Protein UXT (UXT) LDTP13125 0.58  LDD0292 
Putative protein FAM10A5 (ST13P5) LDTP17811 0.72  LDD0292 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 1.01  LDD0292 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 0.37; 1.22  LDD0292 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 0.46; 0.76  LDD0292 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 0.84; 0.94; 0.11 ...  LDD0292 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 1.16  LDD0292 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 1.03; 1.10; 0.05 ...  LDD0292 
Reticulocalbin-1 (RCN1) LDTP06352 7.93  LDD0292 
Reticulon-4 (RTN4) LDTP12412 0.19  LDD0292 
Retinoblastoma-associated protein (RB1) LDTP02146 0.70  LDD0292 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 0.94; 1.30; 0.67 ...  LDD0292 
Rho guanine nucleotide exchange factor 2 (ARHGEF2) LDTP09950 0.49  LDD0292 
Ribosome biogenesis protein WDR12 (WDR12) LDTP11625 1.10  LDD0292 
RNA-binding protein 3 (RBM3) LDTP05226 1.05; 0.97  LDD0292 
RNA-binding protein EWS (EWSR1) LDTP05318 1.14  LDD0292 
RNA-binding protein FUS (FUS) LDTP03775 1.31; 0.97  LDD0292 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 0.91  LDD0292 
Serine/arginine-rich splicing factor 8 (SRSF8) LDTP11117 0.91  LDD0292 
Serpin H1 (SERPINH1) LDTP04363 0.40  LDD0292 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 0.73; 1.28; 1.03 ...  LDD0292 
Small acidic protein (SMAP) LDTP19007 1.17  LDD0292 
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 1.05; 0.79; 1.14 ...  LDD0292 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 0.91; 0.35; 0.97  LDD0292 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 0.87; 0.91  LDD0292 
Small ribosomal subunit protein eS19 (RPS19) LDTP03864 0.87  LDD0292 
Small ribosomal subunit protein eS24 (RPS24) LDTP05012 0.70; 1.24; 0.96  LDD0292 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 0.65  LDD0292 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 0.93; 1.05  LDD0292 
Small ribosomal subunit protein eS4, Y isoform 1 (RPS4Y1) LDTP14653 1.05  LDD0292 
Small ribosomal subunit protein eS4, Y isoform 2 (RPS4Y2) LDTP19820 1.05  LDD0292 
Small ribosomal subunit protein eS7 (RPS7) LDTP04958 0.69  LDD0292 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 1.16; 1.41; 5.63 ...  LDD0292 
Small ribosomal subunit protein uS11 (RPS14) LDTP04970 0.96  LDD0292 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 0.92  LDD0292 
Small ribosomal subunit protein uS13 (RPS18) LDTP04972 1.70; 0.05; 6.60  LDD0292 
Small ribosomal subunit protein uS15 (RPS13) LDTP04974 0.90; 1.23; 1.08  LDD0292 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 0.93; 0.78  LDD0292 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 1.07  LDD0292 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 0.77; 0.84; 0.85  LDD0292 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 0.83; 0.93  LDD0292 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 1.95; 0.84  LDD0292 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 0.24  LDD0292 
Src substrate cortactin (CTTN) LDTP06094 1.02; 0.87; 1.06 ...  LDD0292 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 0.86; 0.59; 0.15 ...  LDD0292 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 0.55; 0.81; 0.37 ...  LDD0292 
Stromal cell-derived factor 2-like protein 1 (SDF2L1) LDTP16047 0.91  LDD0292 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 1.20; 1.12  LDD0292 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 1.32  LDD0292 
Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 0.87  LDD0292 
T-complex protein 1 subunit beta (CCT2) LDTP05113 2.69; 2.27  LDD0292 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 0.88; 0.81  LDD0292 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.39  LDD0292 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 0.75; 0.87  LDD0292 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.98; 0.44; 0.94 ...  LDD0292 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.85  LDD0292 
T-complex protein 1 subunit zeta-2 (CCT6B) LDTP09777 0.85  LDD0292 
Tetratricopeptide repeat protein 1 (TTC1) LDTP15840 1.16  LDD0292 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 0.76  LDD0292 
Transcription elongation factor A protein 1 (TCEA1) LDTP03209 1.56  LDD0292 
Transcription elongation factor SPT6 (SUPT6H) LDTP07928 1.36  LDD0292 
Transgelin-2 (TAGLN2) LDTP03846 0.56; 1.06; 1.02  LDD0292 
Translation initiation factor eIF2B subunit delta (EIF2B4) LDTP13318 0.94  LDD0292 
Translationally-controlled tumor protein (TPT1) LDTP02683 0.81; 0.47  LDD0292 
Transmembrane glycoprotein NMB (GPNMB) LDTP06237 1.36  LDD0292 
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WDR6) LDTP12296 0.98  LDD0292 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 1.14  LDD0292 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 1.24  LDD0292 
Tubulin beta chain (TUBB) LDTP02205 0.94; 0.91; 0.91 ...  LDD0292 
Tubulin beta-2A chain (TUBB2A) LDTP05998 0.05; 1.08; 1.05 ...  LDD0292 
Tubulin beta-2B chain (TUBB2B) LDTP11277 0.62; 1.05; 0.94 ...  LDD0292 
Tubulin beta-3 chain (TUBB3) LDTP05904 0.89; 0.93; 1.04 ...  LDD0292 
Tubulin beta-4A chain (TUBB4A) LDTP02037 0.87; 1.07; 0.92 ...  LDD0292 
Tubulin beta-4B chain (TUBB4B) LDTP05076 0.62; 0.94; 0.89 ...  LDD0292 
Tubulin beta-6 chain (TUBB6) LDTP11233 1.24; 1.03; 0.29 ...  LDD0292 
Tubulin gamma-1 chain (TUBG1) LDTP03213 0.92  LDD0292 
Tubulin gamma-2 chain (TUBG2) LDTP12512 0.92  LDD0292 
Tubulin-folding cofactor B (TBCB) LDTP10860 1.28; 1.00  LDD0292 
U6 snRNA-associated Sm-like protein LSm2 (LSM2) LDTP13946 0.97  LDD0292 
Ubiquilin-1 (UBQLN1) LDTP13626 0.94  LDD0292 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 0.41  LDD0292 
Ubiquitin-fold modifier 1 (UFM1) LDTP04946 1.45  LDD0292 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 0.96  LDD0292 
Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) LDTP11534 0.87  LDD0292 
Vacuolar fusion protein CCZ1 homolog (CCZ1) LDTP14797 0.52  LDD0292 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 1.58  LDD0292 
Vimentin (VIM) LDTP02297 0.91; 0.99; 0.49 ...  LDD0292 
Vinculin (VCL) LDTP02946 1.09; 1.20  LDD0292 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.09  LDD0292 
WD repeat-containing protein 1 (WDR1) LDTP01118 1.37; 1.64; 0.48 ...  LDD0292 
WD repeat-containing protein 5 (WDR5) LDTP04948 0.96  LDD0292 
WW domain-binding protein 2 (WBP2) LDTP10033 0.91; 0.91; 0.85 ...  LDD0292 
Zyxin (ZYX) LDTP06507 0.21; 1.21  LDD0292 
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Full Information of The Labelling Profiles of This Competitor

HHS-482
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB211
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cell lysate (DM93)
Interaction Atlas ID  LDD0292  Download The Altas

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.