Details of the Target

General Information of Target

Target ID LDTP05918
Target Name Histone deacetylase 1 (HDAC1)
Gene Name HDAC1
Gene ID 3065
Synonyms
RPD3L1; Histone deacetylase 1; HD1; EC 3.5.1.98; Protein deacetylase HDAC1; EC 3.5.1.-; Protein decrotonylase HDAC1; EC 3.5.1.-
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAN
AEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAS
AVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG
DGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI
FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG
GGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLE
KIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEF
SDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK
LA
Target Type
Successful
Target Bioclass
Enzyme
Family
Histone deacetylase family, HD type 1 subfamily
Subcellular location
Nucleus
Function
Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. As part of the SIN3B complex is recruited downstream of the constitutively active genes transcriptional start sites through interaction with histones and mitigates histone acetylation and RNA polymerase II progression within transcribed regions contributing to the regulation of transcription. Also functions as a deacetylase for non-histone targets, such as NR1D2, RELA, SP1, SP3, STAT3 and TSHZ3. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium stimulation, HDAC1 is released from the complex and CREBBP is recruited, which facilitates transcriptional activation. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Deacetylates 'Lys-310' in RELA and thereby inhibits the transcriptional activity of NF-kappa-B. Deacetylates NR1D2 and abrogates the effect of KAT5-mediated relieving of NR1D2 transcription repression activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Involved in CIART-mediated transcriptional repression of the circadian transcriptional activator: CLOCK-BMAL1 heterodimer. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex or CRY1 through histone deacetylation. In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones.
TTD ID
T68547
Uniprot ID
Q13547
DrugMap ID
TT6R7JZ
Ensemble ID
ENST00000373548.8
HGNC ID
HGNC:4852
ChEMBL ID
CHEMBL325

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 35 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		13.79  LDD0402  [1]
W1
 Probe Info  		21.08  LDD0235  [2]
TH211
 Probe Info  		Y237(20.00); Y87(17.85); Y201(15.19); Y221(11.33)  LDD0257  [3]
TH214
 Probe Info  		Y358(20.00); Y87(14.51); Y221(10.09); Y201(10.03)  LDD0258  [3]
TH216
 Probe Info  		Y358(20.00); Y67(20.00); Y72(20.00); Y226(14.81)  LDD0259  [3]
STPyne
 Probe Info  		K74(1.39)  LDD0277  [4]
Probe 1
 Probe Info  		Y54(16.14); Y201(25.52); Y204(9.96); Y221(43.17)  LDD3495  [5]
SAHA-CA-4PAP
 Probe Info  		20.00  LDD0269  [6]
BTD
 Probe Info  		C408(0.99)  LDD1700  [7]
AHL-Pu-1
 Probe Info  		C408(2.43)  LDD0169  [8]
HPAP
 Probe Info  		3.07  LDD0063  [9]
HHS-482
 Probe Info  		Y87(0.82)  LDD0285  [10]
HHS-475
 Probe Info  		Y87(0.89)  LDD0264  [11]
HHS-465
 Probe Info  		Y87(10.00)  LDD2237  [12]
DBIA
 Probe Info  		C273(1.00); C408(0.93)  LDD0078  [13]
ATP probe
 Probe Info  		K31(0.00); K89(0.00)  LDD0199  [14]
4-Iodoacetamidophenylacetylene
 Probe Info  		C408(0.00); C151(0.00); C273(0.00); C261(0.00)  LDD0038  [15]
IA-alkyne
 Probe Info  		C273(0.00); C261(0.00)  LDD0032  [16]
IPIAA_L
 Probe Info  		N.A.  LDD0031  [17]
Lodoacetamide azide
 Probe Info  		C408(0.00); C12(0.00); C273(0.00); C261(0.00)  LDD0037  [15]
NAIA_4
 Probe Info  		N.A.  LDD2226  [18]
TFBX
 Probe Info  		N.A.  LDD0027  [19]
WYneN
 Probe Info  		N.A.  LDD0021  [20]
Compound 10
 Probe Info  		N.A.  LDD2216  [21]
ENE
 Probe Info  		N.A.  LDD0006  [20]
IPM
 Probe Info  		C273(0.00); C408(0.00)  LDD0005  [20]
NPM
 Probe Info  		N.A.  LDD0016  [20]
Phosphinate-6
 Probe Info  		C408(0.00); C100(0.00); C284(0.00)  LDD0018  [22]
Ox-W18
 Probe Info  		N.A.  LDD2175  [23]
1c-yne
 Probe Info  		N.A.  LDD0228  [24]
Acrolein
 Probe Info  		C261(0.00); C408(0.00); H68(0.00); C273(0.00)  LDD0217  [25]
Crotonaldehyde
 Probe Info  		C408(0.00); C273(0.00)  LDD0219  [25]
Methacrolein
 Probe Info  		N.A.  LDD0218  [25]
AOyne
 Probe Info  		12.00  LDD0443  [26]
NAIA_5
 Probe Info  		C416(0.00); C408(0.00); C151(0.00); C12(0.00)  LDD2223  [18]
PAL-AfBPP Probe
Click To Hide/Show 8 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C354
 Probe Info  		7.06  LDD2015  [27]
FFF probe13
 Probe Info  		7.78  LDD0475  [28]
FFF probe3
 Probe Info  		5.03  LDD0465  [28]
STS-1
 Probe Info  		N.A.  LDD0136  [29]
STS-2
 Probe Info  		2.00  LDD0139  [29]
VE-P
 Probe Info  		N.A.  LDD0396  [30]
SAHA-CA-3PAP
 Probe Info  		N.A.  LDD0363  [6]
SAHA-CA-8PAP
 Probe Info  		25.43  LDD0362  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C408(0.56)  LDD2095  [7]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C408(0.79)  LDD2130  [7]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C408(1.22)  LDD2152  [7]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C408(1.04)  LDD2103  [7]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C408(0.49)  LDD2132  [7]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C408(0.90)  LDD2131  [7]
 LDCM0025  4SU-RNA HEK-293T C408(2.07)  LDD0172  [8]
 LDCM0026  4SU-RNA+native RNA HEK-293T C408(2.43)  LDD0169  [8]
 LDCM0214  AC1 HCT 116 C273(1.09); C311(1.07); C408(1.24)  LDD0531  [13]
 LDCM0215  AC10 HCT 116 C261(0.64); C273(1.04); C311(0.94); C408(1.16)  LDD0532  [13]
 LDCM0216  AC100 HCT 116 C261(0.75); C273(0.87); C408(1.19)  LDD0533  [13]
 LDCM0217  AC101 HCT 116 C261(0.78); C273(0.82); C408(1.12)  LDD0534  [13]
 LDCM0218  AC102 HCT 116 C261(0.85); C273(0.84); C408(1.05)  LDD0535  [13]
 LDCM0219  AC103 HCT 116 C261(0.81); C273(0.74); C408(1.32)  LDD0536  [13]
 LDCM0220  AC104 HCT 116 C261(0.64); C273(0.84); C408(1.00)  LDD0537  [13]
 LDCM0221  AC105 HCT 116 C261(0.57); C273(0.76); C408(1.28)  LDD0538  [13]
 LDCM0222  AC106 HCT 116 C261(0.66); C273(0.76); C408(1.22)  LDD0539  [13]
 LDCM0223  AC107 HCT 116 C261(0.61); C273(0.94); C408(1.26)  LDD0540  [13]
 LDCM0224  AC108 HCT 116 C261(0.77); C273(0.89); C408(1.03)  LDD0541  [13]
 LDCM0225  AC109 HCT 116 C261(0.82); C273(0.85); C408(0.97)  LDD0542  [13]
 LDCM0226  AC11 HCT 116 C261(0.65); C273(1.17); C311(0.94); C408(1.23)  LDD0543  [13]
 LDCM0227  AC110 HCT 116 C261(0.90); C273(0.86); C408(1.02)  LDD0544  [13]
 LDCM0228  AC111 HCT 116 C261(0.95); C273(0.83); C408(1.05)  LDD0545  [13]
 LDCM0229  AC112 HCT 116 C261(0.78); C273(0.93); C408(1.25)  LDD0546  [13]
 LDCM0230  AC113 HCT 116 C12(1.13); C273(1.16); C408(1.08)  LDD0547  [13]
 LDCM0231  AC114 HCT 116 C12(1.37); C273(1.07); C408(1.24)  LDD0548  [13]
 LDCM0232  AC115 HCT 116 C12(1.34); C273(1.02); C408(1.52)  LDD0549  [13]
 LDCM0233  AC116 HCT 116 C12(1.48); C273(1.07); C408(1.29)  LDD0550  [13]
 LDCM0234  AC117 HCT 116 C12(1.15); C273(1.07); C408(1.18)  LDD0551  [13]
 LDCM0235  AC118 HCT 116 C12(1.10); C273(1.21); C408(1.09)  LDD0552  [13]
 LDCM0236  AC119 HCT 116 C12(1.41); C273(1.07); C408(1.13)  LDD0553  [13]
 LDCM0237  AC12 HCT 116 C261(0.93); C273(1.09); C311(1.02); C408(1.06)  LDD0554  [13]
 LDCM0238  AC120 HCT 116 C12(1.29); C273(1.05); C408(1.18)  LDD0555  [13]
 LDCM0239  AC121 HCT 116 C12(0.91); C273(1.09); C408(1.15)  LDD0556  [13]
 LDCM0240  AC122 HCT 116 C12(1.01); C273(1.17); C408(1.09)  LDD0557  [13]
 LDCM0241  AC123 HCT 116 C12(1.57); C273(1.16); C408(1.07)  LDD0558  [13]
 LDCM0242  AC124 HCT 116 C12(1.15); C273(1.15); C408(0.99)  LDD0559  [13]
 LDCM0243  AC125 HCT 116 C12(1.24); C273(1.11); C408(1.23)  LDD0560  [13]
 LDCM0244  AC126 HCT 116 C12(1.15); C273(1.02); C408(1.34)  LDD0561  [13]
 LDCM0245  AC127 HCT 116 C12(1.07); C273(1.08); C408(1.28)  LDD0562  [13]
 LDCM0246  AC128 HCT 116 C100(0.74); C12(0.43); C273(1.03); C311(0.60)  LDD0563  [13]
 LDCM0247  AC129 HCT 116 C100(1.28); C12(0.46); C273(1.20); C311(0.94)  LDD0564  [13]
 LDCM0249  AC130 HCT 116 C100(0.98); C12(0.55); C273(1.11); C311(0.94)  LDD0566  [13]
 LDCM0250  AC131 HCT 116 C100(1.13); C12(0.77); C273(1.02); C311(1.10)  LDD0567  [13]
 LDCM0251  AC132 HCT 116 C100(0.99); C12(0.50); C273(1.06); C311(0.84)  LDD0568  [13]
 LDCM0252  AC133 HCT 116 C100(0.99); C12(0.55); C273(1.09); C311(0.98)  LDD0569  [13]
 LDCM0253  AC134 HCT 116 C100(0.87); C12(0.44); C273(0.97); C311(0.82)  LDD0570  [13]
 LDCM0254  AC135 HCT 116 C100(0.91); C12(0.53); C273(1.03); C311(0.97)  LDD0571  [13]
 LDCM0255  AC136 HCT 116 C100(1.00); C12(0.67); C273(1.11); C311(0.96)  LDD0572  [13]
 LDCM0256  AC137 HCT 116 C100(1.02); C12(0.91); C273(1.15); C311(0.75)  LDD0573  [13]
 LDCM0257  AC138 HCT 116 C100(0.99); C12(0.66); C273(1.06); C311(0.85)  LDD0574  [13]
 LDCM0258  AC139 HCT 116 C100(1.04); C12(0.60); C273(1.00); C311(0.97)  LDD0575  [13]
 LDCM0259  AC14 HCT 116 C261(0.75); C273(1.14); C311(0.88); C408(1.12)  LDD0576  [13]
 LDCM0260  AC140 HCT 116 C100(0.92); C12(0.47); C273(0.98); C311(0.81)  LDD0577  [13]
 LDCM0261  AC141 HCT 116 C100(0.95); C12(0.39); C273(1.02); C311(0.88)  LDD0578  [13]
 LDCM0262  AC142 HCT 116 C100(1.28); C12(0.86); C273(1.22); C311(0.96)  LDD0579  [13]
 LDCM0263  AC143 HCT 116 C100(0.82); C12(0.80); C273(1.20); C408(1.26)  LDD0580  [13]
 LDCM0264  AC144 HCT 116 C100(0.62); C12(0.66); C408(1.27); C273(1.28)  LDD0581  [13]
 LDCM0265  AC145 HCT 116 C12(0.65); C100(0.73); C273(1.17); C408(1.18)  LDD0582  [13]
 LDCM0266  AC146 HCT 116 C100(0.65); C12(0.92); C273(1.28); C408(1.32)  LDD0583  [13]
 LDCM0267  AC147 HCT 116 C100(0.53); C12(0.65); C273(1.25); C408(1.44)  LDD0584  [13]
 LDCM0268  AC148 HCT 116 C12(0.38); C100(0.38); C273(1.01); C408(1.52)  LDD0585  [13]
 LDCM0269  AC149 HCT 116 C100(0.60); C12(0.64); C273(1.11); C408(1.42)  LDD0586  [13]
 LDCM0270  AC15 HCT 116 C261(0.70); C311(1.00); C273(1.08); C408(1.15)  LDD0587  [13]
 LDCM0271  AC150 HCT 116 C12(1.11); C408(1.21); C273(1.22); C100(1.29)  LDD0588  [13]
 LDCM0272  AC151 HCT 116 C12(0.88); C408(1.23); C100(1.30); C273(1.34)  LDD0589  [13]
 LDCM0273  AC152 HCT 116 C12(0.64); C100(0.72); C273(1.28); C408(1.53)  LDD0590  [13]
 LDCM0274  AC153 HCT 116 C12(0.36); C100(0.40); C273(1.10); C408(1.57)  LDD0591  [13]
 LDCM0621  AC154 HCT 116 C100(0.64); C12(0.69); C273(1.08); C408(1.42)  LDD2158  [13]
 LDCM0622  AC155 HCT 116 C100(0.55); C12(0.75); C273(1.12); C408(1.37)  LDD2159  [13]
 LDCM0623  AC156 HCT 116 C100(0.97); C12(0.81); C273(1.20); C408(1.10)  LDD2160  [13]
 LDCM0624  AC157 HCT 116 C100(0.59); C12(1.01); C273(1.23); C408(1.15)  LDD2161  [13]
 LDCM0276  AC17 HCT 116 C261(1.04); C408(1.08); C273(1.11)  LDD0593  [13]
 LDCM0277  AC18 HCT 116 C261(0.94); C273(1.17); C408(1.52)  LDD0594  [13]
 LDCM0278  AC19 HCT 116 C261(1.07); C273(1.16); C408(1.31)  LDD0595  [13]
 LDCM0279  AC2 HCT 116 C311(0.93); C273(0.98); C408(1.24)  LDD0596  [13]
 LDCM0280  AC20 HCT 116 C261(1.15); C273(1.24); C408(1.28)  LDD0597  [13]
 LDCM0281  AC21 HCT 116 C273(1.20); C408(1.30); C261(1.57)  LDD0598  [13]
 LDCM0282  AC22 HCT 116 C261(1.05); C408(1.06); C273(1.22)  LDD0599  [13]
 LDCM0283  AC23 HCT 116 C261(1.09); C273(1.31); C408(1.32)  LDD0600  [13]
 LDCM0284  AC24 HCT 116 C273(1.08); C408(1.08); C261(1.68)  LDD0601  [13]
 LDCM0285  AC25 HCT 116 C261(0.67); C273(0.97); C408(1.12)  LDD0602  [13]
 LDCM0286  AC26 HCT 116 C261(0.84); C273(0.93); C408(1.20)  LDD0603  [13]
 LDCM0287  AC27 HCT 116 C273(0.83); C261(1.12); C408(1.29)  LDD0604  [13]
 LDCM0288  AC28 HCT 116 C261(0.68); C273(0.91); C408(1.24)  LDD0605  [13]
 LDCM0289  AC29 HCT 116 C273(0.95); C408(1.24); C261(1.44)  LDD0606  [13]
 LDCM0290  AC3 HCT 116 C273(0.99); C311(1.04); C408(1.23)  LDD0607  [13]
 LDCM0291  AC30 HCT 116 C273(0.83); C261(1.12); C408(1.28)  LDD0608  [13]
 LDCM0292  AC31 HCT 116 C273(0.89); C261(0.94); C408(1.19)  LDD0609  [13]
 LDCM0293  AC32 HCT 116 C273(0.82); C261(1.15); C408(1.45)  LDD0610  [13]
 LDCM0294  AC33 HCT 116 C261(0.79); C273(0.86); C408(1.37)  LDD0611  [13]
 LDCM0295  AC34 HCT 116 C261(0.82); C273(0.92); C408(1.41)  LDD0612  [13]
 LDCM0296  AC35 HCT 116 C408(0.85); C100(0.87); C261(1.38)  LDD0613  [13]
 LDCM0297  AC36 HCT 116 C100(0.69); C408(0.99); C261(1.37)  LDD0614  [13]
 LDCM0298  AC37 HCT 116 C100(0.63); C408(0.96); C261(1.18)  LDD0615  [13]
 LDCM0299  AC38 HCT 116 C100(0.92); C408(1.02); C261(1.26)  LDD0616  [13]
 LDCM0300  AC39 HCT 116 C100(0.86); C408(1.20); C261(1.35)  LDD0617  [13]
 LDCM0301  AC4 HCT 116 C311(0.93); C273(1.04); C408(1.26)  LDD0618  [13]
 LDCM0302  AC40 HCT 116 C100(0.60); C408(0.99); C261(1.00)  LDD0619  [13]
 LDCM0303  AC41 HCT 116 C100(0.92); C261(0.93); C408(1.21)  LDD0620  [13]
 LDCM0304  AC42 HCT 116 C100(0.77); C261(1.08); C408(1.24)  LDD0621  [13]
 LDCM0305  AC43 HCT 116 C100(1.00); C261(1.30); C408(1.36)  LDD0622  [13]
 LDCM0306  AC44 HCT 116 C261(0.83); C100(0.86); C408(0.99)  LDD0623  [13]
 LDCM0307  AC45 HCT 116 C100(0.75); C408(1.16); C261(1.24)  LDD0624  [13]
 LDCM0308  AC46 HCT 116 C273(1.01); C408(1.04); C261(1.06)  LDD0625  [13]
 LDCM0309  AC47 HCT 116 C273(1.06); C408(1.10); C261(1.13)  LDD0626  [13]
 LDCM0310  AC48 HCT 116 C273(1.06); C408(1.11); C261(1.15)  LDD0627  [13]
 LDCM0311  AC49 HCT 116 C261(0.68); C273(0.84); C408(1.19)  LDD0628  [13]
 LDCM0312  AC5 HCT 116 C311(0.77); C273(1.01); C408(1.44)  LDD0629  [13]
 LDCM0313  AC50 HCT 116 C261(0.72); C273(0.89); C408(1.11)  LDD0630  [13]
 LDCM0314  AC51 HCT 116 C408(0.87); C273(1.01); C261(1.30)  LDD0631  [13]
 LDCM0315  AC52 HCT 116 C408(1.02); C273(1.08); C261(1.10)  LDD0632  [13]
 LDCM0316  AC53 HCT 116 C261(0.87); C273(0.92); C408(0.98)  LDD0633  [13]
 LDCM0317  AC54 HCT 116 C261(0.86); C273(0.92); C408(1.09)  LDD0634  [13]
 LDCM0318  AC55 HCT 116 C261(0.70); C273(0.91); C408(1.15)  LDD0635  [13]
 LDCM0319  AC56 HCT 116 C261(0.74); C273(0.92); C408(1.37)  LDD0636  [13]
 LDCM0320  AC57 HCT 116 C273(1.10); C408(1.41)  LDD0637  [13]
 LDCM0321  AC58 HCT 116 C273(0.99); C408(1.29)  LDD0638  [13]
 LDCM0322  AC59 HCT 116 C273(0.96); C408(1.45)  LDD0639  [13]
 LDCM0323  AC6 HCT 116 C261(0.63); C311(0.74); C273(0.99); C408(1.15)  LDD0640  [13]
 LDCM0324  AC60 HCT 116 C273(1.16); C408(1.33)  LDD0641  [13]
 LDCM0325  AC61 HCT 116 C273(1.07); C408(1.36)  LDD0642  [13]
 LDCM0326  AC62 HCT 116 C273(1.05); C408(1.70)  LDD0643  [13]
 LDCM0327  AC63 HCT 116 C273(1.17); C408(1.54)  LDD0644  [13]
 LDCM0328  AC64 HCT 116 C273(1.08); C408(1.46)  LDD0645  [13]
 LDCM0329  AC65 HCT 116 C273(1.18); C408(1.61)  LDD0646  [13]
 LDCM0330  AC66 HCT 116 C273(1.28); C408(1.67)  LDD0647  [13]
 LDCM0331  AC67 HCT 116 C273(0.96); C408(1.52)  LDD0648  [13]
 LDCM0332  AC68 HCT 116 C273(0.99); C408(1.03)  LDD0649  [13]
 LDCM0333  AC69 HCT 116 C273(1.02); C408(1.06)  LDD0650  [13]
 LDCM0334  AC7 HCT 116 C261(0.74); C311(0.77); C408(1.01); C273(1.10)  LDD0651  [13]
 LDCM0335  AC70 HCT 116 C273(0.84); C408(1.11)  LDD0652  [13]
 LDCM0336  AC71 HCT 116 C408(0.89); C273(1.07)  LDD0653  [13]
 LDCM0337  AC72 HCT 116 C273(1.00); C408(1.06)  LDD0654  [13]
 LDCM0338  AC73 HCT 116 C273(0.80); C408(1.24)  LDD0655  [13]
 LDCM0339  AC74 HCT 116 C273(0.87); C408(1.16)  LDD0656  [13]
 LDCM0340  AC75 HCT 116 C273(0.90); C408(1.27)  LDD0657  [13]
 LDCM0341  AC76 HCT 116 C273(0.97); C408(1.16)  LDD0658  [13]
 LDCM0342  AC77 HCT 116 C273(0.94); C408(1.16)  LDD0659  [13]
 LDCM0343  AC78 HCT 116 C408(1.03); C273(1.24)  LDD0660  [13]
 LDCM0344  AC79 HCT 116 C273(0.92); C408(1.06)  LDD0661  [13]
 LDCM0345  AC8 HCT 116 C311(0.95); C273(1.02); C408(1.09); C261(1.33)  LDD0662  [13]
 LDCM0346  AC80 HCT 116 C273(0.96); C408(1.06)  LDD0663  [13]
 LDCM0347  AC81 HCT 116 C408(0.93); C273(1.24)  LDD0664  [13]
 LDCM0348  AC82 HCT 116 C273(0.94); C408(1.33)  LDD0665  [13]
 LDCM0349  AC83 HCT 116 C12(0.65); C261(0.73); C273(0.90); C408(1.48)  LDD0666  [13]
 LDCM0350  AC84 HCT 116 C261(0.79); C273(0.94); C12(1.11); C408(1.44)  LDD0667  [13]
 LDCM0351  AC85 HCT 116 C273(0.98); C261(1.06); C408(1.51); C12(1.86)  LDD0668  [13]
 LDCM0352  AC86 HCT 116 C261(0.85); C273(0.90); C12(0.95); C408(1.23)  LDD0669  [13]
 LDCM0353  AC87 HCT 116 C273(0.92); C408(1.13); C261(1.15); C12(1.62)  LDD0670  [13]
 LDCM0354  AC88 HCT 116 C12(0.85); C273(0.87); C261(0.92); C408(1.32)  LDD0671  [13]
 LDCM0355  AC89 HCT 116 C261(0.84); C273(0.96); C12(1.12); C408(1.30)  LDD0672  [13]
 LDCM0357  AC90 HCT 116 C273(0.99); C261(1.02); C12(1.11); C408(1.17)  LDD0674  [13]
 LDCM0358  AC91 HCT 116 C12(0.59); C261(0.80); C273(0.83); C408(1.46)  LDD0675  [13]
 LDCM0359  AC92 HCT 116 C12(0.55); C261(0.91); C273(0.91); C408(1.60)  LDD0676  [13]
 LDCM0360  AC93 HCT 116 C12(0.81); C261(0.82); C273(1.09); C408(1.35)  LDD0677  [13]
 LDCM0361  AC94 HCT 116 C273(1.04); C261(1.07); C408(1.24); C12(1.77)  LDD0678  [13]
 LDCM0362  AC95 HCT 116 C12(1.00); C273(1.03); C408(1.25); C261(1.29)  LDD0679  [13]
 LDCM0363  AC96 HCT 116 C261(0.88); C12(0.90); C273(0.94); C408(1.38)  LDD0680  [13]
 LDCM0364  AC97 HCT 116 C273(0.91); C261(0.94); C12(1.18); C408(1.64)  LDD0681  [13]
 LDCM0365  AC98 HCT 116 C261(0.33); C273(0.65); C408(1.32)  LDD0682  [13]
 LDCM0366  AC99 HCT 116 C261(0.63); C273(0.91); C408(1.12)  LDD0683  [13]
 LDCM0545  Acetamide MDA-MB-231 C408(0.51)  LDD2138  [7]
 LDCM0520  AKOS000195272 MDA-MB-231 C408(0.82)  LDD2113  [7]
 LDCM0248  AKOS034007472 HCT 116 C261(1.46); C273(1.10); C311(0.85); C408(1.03)  LDD0565  [13]
 LDCM0356  AKOS034007680 HCT 116 C261(0.80); C311(0.88); C408(1.10); C273(1.10)  LDD0673  [13]
 LDCM0275  AKOS034007705 HCT 116 C311(0.71); C261(0.72); C273(0.97); C408(1.58)  LDD0592  [13]
 LDCM0020  ARS-1620 HCC44 C273(1.00); C408(0.93)  LDD0078  [13]
 LDCM0102  BDHI 8 Jurkat C416(5.29)  LDD0204  [31]
 LDCM0498  BS-3668 MDA-MB-231 C408(0.41)  LDD2091  [7]
 LDCM0108  Chloroacetamide HeLa H344(0.00); C261(0.00); C273(0.00); C408(0.00)  LDD0222  [25]
 LDCM0632  CL-Sc Hep-G2 C408(0.92); C416(0.83)  LDD2227  [18]
 LDCM0367  CL1 HCT 116 C408(0.87); C273(1.04); C261(1.18); C100(1.34)  LDD0684  [13]
 LDCM0368  CL10 HCT 116 C100(0.95); C273(0.98); C311(1.18); C408(1.19)  LDD0685  [13]
 LDCM0369  CL100 HCT 116 C311(0.76); C273(1.01); C408(1.28)  LDD0686  [13]
 LDCM0370  CL101 HCT 116 C311(0.99); C261(1.05); C273(1.06); C408(1.25)  LDD0687  [13]
 LDCM0371  CL102 HCT 116 C311(0.93); C408(1.03); C261(1.10); C273(1.15)  LDD0688  [13]
 LDCM0372  CL103 HCT 116 C311(0.93); C261(1.02); C408(1.03); C273(1.08)  LDD0689  [13]
 LDCM0373  CL104 HCT 116 C261(0.73); C408(0.99); C273(1.06); C311(1.74)  LDD0690  [13]
 LDCM0374  CL105 HCT 116 C273(1.08); C261(1.27); C408(1.37)  LDD0691  [13]
 LDCM0375  CL106 HCT 116 C273(1.17); C261(1.21); C408(1.73)  LDD0692  [13]
 LDCM0376  CL107 HCT 116 C261(0.96); C273(1.23); C408(1.63)  LDD0693  [13]
 LDCM0377  CL108 HCT 116 C261(0.98); C273(1.03); C408(1.41)  LDD0694  [13]
 LDCM0378  CL109 HCT 116 C273(1.18); C261(1.25); C408(1.28)  LDD0695  [13]
 LDCM0379  CL11 HCT 116 C100(0.85); C261(0.93); C273(0.97); C311(1.06)  LDD0696  [13]
 LDCM0380  CL110 HCT 116 C261(0.87); C273(1.21); C408(1.44)  LDD0697  [13]
 LDCM0381  CL111 HCT 116 C261(1.03); C273(1.35); C408(1.38)  LDD0698  [13]
 LDCM0382  CL112 HCT 116 C273(0.91); C261(0.95); C408(1.08)  LDD0699  [13]
 LDCM0383  CL113 HCT 116 C261(0.83); C273(0.84); C408(1.35)  LDD0700  [13]
 LDCM0384  CL114 HCT 116 C273(0.91); C261(1.14); C408(1.21)  LDD0701  [13]
 LDCM0385  CL115 HCT 116 C261(0.68); C273(0.81); C408(1.24)  LDD0702  [13]
 LDCM0386  CL116 HCT 116 C261(0.74); C273(0.83); C408(1.23)  LDD0703  [13]
 LDCM0387  CL117 HCT 116 C100(0.55); C261(0.70); C408(1.22)  LDD0704  [13]
 LDCM0388  CL118 HCT 116 C100(0.71); C261(1.07); C408(1.11)  LDD0705  [13]
 LDCM0389  CL119 HCT 116 C100(0.79); C261(1.16); C408(1.28)  LDD0706  [13]
 LDCM0390  CL12 HCT 116 C100(0.74); C273(0.82); C261(0.84); C311(0.95)  LDD0707  [13]
 LDCM0391  CL120 HCT 116 C100(0.71); C261(0.75); C408(1.27)  LDD0708  [13]
 LDCM0392  CL121 HCT 116 C261(0.63); C273(0.91); C408(1.16)  LDD0709  [13]
 LDCM0393  CL122 HCT 116 C273(0.96); C408(1.04); C261(1.08)  LDD0710  [13]
 LDCM0394  CL123 HCT 116 C261(0.94); C273(1.03); C408(1.11)  LDD0711  [13]
 LDCM0395  CL124 HCT 116 C261(0.85); C273(0.94); C408(1.20)  LDD0712  [13]
 LDCM0396  CL125 HCT 116 C273(1.09); C408(1.28)  LDD0713  [13]
 LDCM0397  CL126 HCT 116 C408(1.03); C273(1.08)  LDD0714  [13]
 LDCM0398  CL127 HCT 116 C273(1.12); C408(1.18)  LDD0715  [13]
 LDCM0399  CL128 HCT 116 C273(1.00); C408(1.46)  LDD0716  [13]
 LDCM0400  CL13 HCT 116 C273(0.95); C100(1.03); C408(1.06); C261(1.14)  LDD0717  [13]
 LDCM0401  CL14 HCT 116 C273(0.95); C408(1.00); C100(1.11); C311(1.27)  LDD0718  [13]
 LDCM0402  CL15 HCT 116 C311(0.95); C273(1.05); C408(1.12); C261(1.18)  LDD0719  [13]
 LDCM0403  CL16 HCT 116 C261(0.94); C273(1.05); C408(1.14)  LDD0720  [13]
 LDCM0404  CL17 HCT 116 C261(0.78); C273(1.07); C12(1.09); C408(1.16)  LDD0721  [13]
 LDCM0405  CL18 HCT 116 C12(0.87); C408(1.08); C261(1.22); C273(1.23)  LDD0722  [13]
 LDCM0406  CL19 HCT 116 C261(0.75); C273(0.99); C408(1.06); C12(1.26)  LDD0723  [13]
 LDCM0407  CL2 HCT 116 C408(0.94); C273(1.04); C100(1.14); C311(1.21)  LDD0724  [13]
 LDCM0408  CL20 HCT 116 C261(0.68); C273(0.90); C12(1.25); C408(1.44)  LDD0725  [13]
 LDCM0409  CL21 HCT 116 C261(0.71); C273(1.06); C408(1.31); C12(1.59)  LDD0726  [13]
 LDCM0410  CL22 HCT 116 C261(0.57); C273(0.87); C12(1.21); C408(1.83)  LDD0727  [13]
 LDCM0411  CL23 HCT 116 C261(0.74); C273(0.99); C12(1.04); C408(1.09)  LDD0728  [13]
 LDCM0412  CL24 HCT 116 C261(0.63); C12(0.90); C273(0.90); C408(1.59)  LDD0729  [13]
 LDCM0413  CL25 HCT 116 C12(0.99); C261(0.61); C273(1.05); C408(1.35)  LDD0730  [13]
 LDCM0414  CL26 HCT 116 C12(0.97); C261(0.70); C273(0.99); C408(1.33)  LDD0731  [13]
 LDCM0415  CL27 HCT 116 C12(0.97); C261(0.85); C273(0.99); C408(1.05)  LDD0732  [13]
 LDCM0416  CL28 HCT 116 C12(0.89); C261(0.77); C273(0.96); C408(1.23)  LDD0733  [13]
 LDCM0417  CL29 HCT 116 C12(1.09); C261(0.74); C273(1.01); C408(1.27)  LDD0734  [13]
 LDCM0418  CL3 HCT 116 C100(0.89); C261(1.08); C273(0.95); C311(1.04)  LDD0735  [13]
 LDCM0419  CL30 HCT 116 C12(2.40); C261(0.83); C273(1.15); C408(1.02)  LDD0736  [13]
 LDCM0420  CL31 HCT 116 C12(0.92); C261(1.08); C273(0.93); C408(0.95)  LDD0737  [13]
 LDCM0421  CL32 HCT 116 C261(0.91); C273(1.13); C408(1.15)  LDD0738  [13]
 LDCM0422  CL33 HCT 116 C261(0.98); C273(1.06); C408(1.13)  LDD0739  [13]
 LDCM0423  CL34 HCT 116 C261(1.00); C273(0.90); C408(0.97)  LDD0740  [13]
 LDCM0424  CL35 HCT 116 C261(0.97); C273(0.83); C408(1.04)  LDD0741  [13]
 LDCM0425  CL36 HCT 116 C261(1.07); C273(0.89); C408(0.93)  LDD0742  [13]
 LDCM0426  CL37 HCT 116 C261(0.92); C273(0.78); C408(0.93)  LDD0743  [13]
 LDCM0428  CL39 HCT 116 C261(0.92); C273(0.87); C408(1.00)  LDD0745  [13]
 LDCM0429  CL4 HCT 116 C100(0.89); C261(0.95); C273(1.00); C311(0.76)  LDD0746  [13]
 LDCM0430  CL40 HCT 116 C261(0.96); C273(0.97); C408(0.97)  LDD0747  [13]
 LDCM0431  CL41 HCT 116 C261(0.97); C273(0.84); C408(0.94)  LDD0748  [13]
 LDCM0432  CL42 HCT 116 C261(0.81); C273(0.81); C408(0.91)  LDD0749  [13]
 LDCM0433  CL43 HCT 116 C261(0.89); C273(0.82); C408(0.94)  LDD0750  [13]
 LDCM0434  CL44 HCT 116 C261(0.95); C273(0.97); C408(0.91)  LDD0751  [13]
 LDCM0435  CL45 HCT 116 C261(1.05); C273(1.04); C408(0.92)  LDD0752  [13]
 LDCM0436  CL46 HCT 116 C261(1.00); C273(1.00); C408(0.90)  LDD0753  [13]
 LDCM0437  CL47 HCT 116 C261(1.02); C273(1.01); C408(0.97)  LDD0754  [13]
 LDCM0438  CL48 HCT 116 C261(1.07); C273(0.98); C408(0.93)  LDD0755  [13]
 LDCM0439  CL49 HCT 116 C261(1.08); C273(0.96); C408(0.86)  LDD0756  [13]
 LDCM0440  CL5 HCT 116 C100(1.10); C261(1.30); C273(0.96); C311(1.18)  LDD0757  [13]
 LDCM0441  CL50 HCT 116 C261(0.94); C273(0.89); C408(0.88)  LDD0758  [13]
 LDCM0442  CL51 HCT 116 C261(1.07); C273(0.99); C408(0.94)  LDD0759  [13]
 LDCM0443  CL52 HCT 116 C261(1.06); C273(0.90); C408(0.99)  LDD0760  [13]
 LDCM0444  CL53 HCT 116 C261(1.05); C273(0.88); C408(0.96)  LDD0761  [13]
 LDCM0445  CL54 HCT 116 C261(0.95); C273(0.96); C408(0.91)  LDD0762  [13]
 LDCM0446  CL55 HCT 116 C261(1.04); C273(0.98); C408(0.90)  LDD0763  [13]
 LDCM0447  CL56 HCT 116 C261(0.88); C273(1.01); C408(0.96)  LDD0764  [13]
 LDCM0448  CL57 HCT 116 C261(0.88); C273(0.97); C408(0.81)  LDD0765  [13]
 LDCM0449  CL58 HCT 116 C261(0.99); C273(1.02); C408(0.83)  LDD0766  [13]
 LDCM0450  CL59 HCT 116 C261(0.90); C273(0.95); C408(0.87)  LDD0767  [13]
 LDCM0451  CL6 HCT 116 C100(1.43); C261(1.37); C273(1.06); C311(1.51)  LDD0768  [13]
 LDCM0452  CL60 HCT 116 C261(0.85); C273(0.96); C408(0.89)  LDD0769  [13]
 LDCM0453  CL61 HCT 116 C273(1.05); C311(1.05); C408(1.12)  LDD0770  [13]
 LDCM0454  CL62 HCT 116 C273(1.05); C311(0.92); C408(1.09)  LDD0771  [13]
 LDCM0455  CL63 HCT 116 C273(1.04); C311(1.09); C408(1.55)  LDD0772  [13]
 LDCM0456  CL64 HCT 116 C273(0.94); C311(1.05); C408(1.33)  LDD0773  [13]
 LDCM0457  CL65 HCT 116 C273(1.00); C311(1.05); C408(1.08)  LDD0774  [13]
 LDCM0458  CL66 HCT 116 C273(0.99); C311(0.91); C408(1.33)  LDD0775  [13]
 LDCM0459  CL67 HCT 116 C273(0.99); C311(0.85); C408(1.33)  LDD0776  [13]
 LDCM0460  CL68 HCT 116 C273(0.99); C311(0.89); C408(1.21)  LDD0777  [13]
 LDCM0461  CL69 HCT 116 C273(1.11); C311(1.35); C408(1.27)  LDD0778  [13]
 LDCM0462  CL7 HCT 116 C100(0.87); C261(1.08); C273(0.99); C311(0.83)  LDD0779  [13]
 LDCM0463  CL70 HCT 116 C273(1.11); C311(0.93); C408(1.34)  LDD0780  [13]
 LDCM0464  CL71 HCT 116 C273(1.06); C311(0.98); C408(1.31)  LDD0781  [13]
 LDCM0465  CL72 HCT 116 C273(1.01); C311(1.06); C408(1.03)  LDD0782  [13]
 LDCM0466  CL73 HCT 116 C273(1.04); C311(1.12); C408(1.15)  LDD0783  [13]
 LDCM0467  CL74 HCT 116 C273(0.92); C311(0.89); C408(1.21)  LDD0784  [13]
 LDCM0469  CL76 HCT 116 C273(1.08); C311(1.44); C408(1.07)  LDD0786  [13]
 LDCM0470  CL77 HCT 116 C273(0.95); C311(0.82); C408(1.03)  LDD0787  [13]
 LDCM0471  CL78 HCT 116 C273(0.98); C311(0.98); C408(1.20)  LDD0788  [13]
 LDCM0472  CL79 HCT 116 C273(0.90); C311(0.79); C408(1.37)  LDD0789  [13]
 LDCM0473  CL8 HCT 116 C100(0.70); C261(0.79); C273(0.87); C311(0.75)  LDD0790  [13]
 LDCM0474  CL80 HCT 116 C273(1.20); C311(1.36); C408(1.08)  LDD0791  [13]
 LDCM0475  CL81 HCT 116 C273(0.94); C311(1.14); C408(1.21)  LDD0792  [13]
 LDCM0476  CL82 HCT 116 C273(0.85); C311(0.63); C408(1.58)  LDD0793  [13]
 LDCM0477  CL83 HCT 116 C273(0.93); C311(0.87); C408(1.45)  LDD0794  [13]
 LDCM0478  CL84 HCT 116 C273(0.85); C311(0.74); C408(1.64)  LDD0795  [13]
 LDCM0479  CL85 HCT 116 C273(1.04); C311(0.91); C408(1.24)  LDD0796  [13]
 LDCM0480  CL86 HCT 116 C273(1.07); C311(1.11); C408(1.14)  LDD0797  [13]
 LDCM0481  CL87 HCT 116 C273(0.97); C311(1.04); C408(1.31)  LDD0798  [13]
 LDCM0482  CL88 HCT 116 C273(0.89); C311(0.92); C408(1.48)  LDD0799  [13]
 LDCM0483  CL89 HCT 116 C273(0.87); C311(0.88); C408(1.87)  LDD0800  [13]
 LDCM0484  CL9 HCT 116 C100(0.89); C261(0.98); C273(0.94); C311(1.02)  LDD0801  [13]
 LDCM0485  CL90 HCT 116 C273(0.96); C311(0.88); C408(0.83)  LDD0802  [13]
 LDCM0486  CL91 HCT 116 C273(0.94); C311(1.01); C408(1.21)  LDD0803  [13]
 LDCM0487  CL92 HCT 116 C273(1.02); C311(0.91); C408(1.31)  LDD0804  [13]
 LDCM0488  CL93 HCT 116 C273(1.01); C311(0.98); C408(1.09)  LDD0805  [13]
 LDCM0489  CL94 HCT 116 C273(0.97); C311(1.00); C408(1.16)  LDD0806  [13]
 LDCM0490  CL95 HCT 116 C273(1.01); C311(0.97); C408(1.27)  LDD0807  [13]
 LDCM0491  CL96 HCT 116 C273(0.97); C311(0.80); C408(1.40)  LDD0808  [13]
 LDCM0492  CL97 HCT 116 C273(0.96); C311(0.79); C408(1.27)  LDD0809  [13]
 LDCM0493  CL98 HCT 116 C273(0.96); C311(0.81); C408(1.28)  LDD0810  [13]
 LDCM0494  CL99 HCT 116 C273(0.95); C311(0.84); C408(1.30)  LDD0811  [13]
 LDCM0495  E2913 HEK-293T C408(0.81); C416(0.79); C12(1.02); C261(1.06)  LDD1698  [32]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C284(2.38); C273(1.41); C408(1.29)  LDD1702  [7]
 LDCM0625  F8 Ramos C408(1.42)  LDD2187  [33]
 LDCM0572  Fragment10 Ramos C408(1.06)  LDD2189  [33]
 LDCM0573  Fragment11 Ramos C273(2.49); C261(1.72)  LDD2190  [33]
 LDCM0574  Fragment12 Ramos C408(0.93); C261(1.27)  LDD2191  [33]
 LDCM0575  Fragment13 Ramos C408(1.04); C273(0.58); C261(1.73)  LDD2192  [33]
 LDCM0576  Fragment14 Ramos C408(1.12); C273(0.81); C261(0.92)  LDD2193  [33]
 LDCM0579  Fragment20 Ramos C408(1.00); C261(0.93)  LDD2194  [33]
 LDCM0580  Fragment21 Ramos C408(0.94); C273(0.99); C261(0.96)  LDD2195  [33]
 LDCM0582  Fragment23 Ramos C408(1.19); C273(1.28); C261(0.98)  LDD2196  [33]
 LDCM0578  Fragment27 Ramos C408(0.80); C273(4.51); C261(1.13)  LDD2197  [33]
 LDCM0586  Fragment28 Ramos C408(0.60); C273(0.71)  LDD2198  [33]
 LDCM0588  Fragment30 Ramos C408(1.12); C273(0.68)  LDD2199  [33]
 LDCM0589  Fragment31 Ramos C408(1.06); C273(0.89); C261(2.03)  LDD2200  [33]
 LDCM0590  Fragment32 Ramos C408(0.87); C261(0.81)  LDD2201  [33]
 LDCM0468  Fragment33 HCT 116 C273(1.05); C311(0.70); C408(1.23)  LDD0785  [13]
 LDCM0596  Fragment38 Ramos C408(0.81); C273(1.14); C261(0.99)  LDD2203  [33]
 LDCM0566  Fragment4 Ramos C408(0.80); C273(1.49)  LDD2184  [33]
 LDCM0427  Fragment51 HCT 116 C261(0.98); C273(0.87); C408(0.84)  LDD0744  [13]
 LDCM0610  Fragment52 Ramos C408(1.70); C273(0.89); C261(1.23)  LDD2204  [33]
 LDCM0614  Fragment56 Ramos C408(1.56); C261(0.94)  LDD2205  [33]
 LDCM0569  Fragment7 Ramos C408(1.09); C273(1.62); C261(0.31)  LDD2186  [33]
 LDCM0571  Fragment9 Ramos C408(1.09); C261(1.05)  LDD2188  [33]
 LDCM0116  HHS-0101 DM93 Y87(0.89)  LDD0264  [11]
 LDCM0117  HHS-0201 DM93 Y87(0.75)  LDD0265  [11]
 LDCM0118  HHS-0301 DM93 Y87(0.72)  LDD0266  [11]
 LDCM0119  HHS-0401 DM93 Y87(0.78)  LDD0267  [11]
 LDCM0120  HHS-0701 DM93 Y87(0.74)  LDD0268  [11]
 LDCM0107  IAA HeLa H344(0.00); C273(0.00); H68(0.00)  LDD0221  [25]
 LDCM0123  JWB131 DM93 Y87(0.82)  LDD0285  [10]
 LDCM0124  JWB142 DM93 Y87(0.53)  LDD0286  [10]
 LDCM0125  JWB146 DM93 Y87(1.06)  LDD0287  [10]
 LDCM0126  JWB150 DM93 Y87(3.09)  LDD0288  [10]
 LDCM0127  JWB152 DM93 Y87(2.15)  LDD0289  [10]
 LDCM0128  JWB198 DM93 Y87(1.30)  LDD0290  [10]
 LDCM0129  JWB202 DM93 Y87(0.36)  LDD0291  [10]
 LDCM0130  JWB211 DM93 Y87(0.89)  LDD0292  [10]
 LDCM0022  KB02 HCT 116 C273(1.95); C408(1.82)  LDD0080  [13]
 LDCM0023  KB03 HCT 116 C273(2.20); C408(1.60)  LDD0081  [13]
 LDCM0024  KB05 HCT 116 C273(1.87); C408(1.52)  LDD0082  [13]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C408(1.05)  LDD2102  [7]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C408(0.41)  LDD2121  [7]
 LDCM0109  NEM HeLa H344(0.00); H68(0.00)  LDD0223  [25]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C408(0.46)  LDD2089  [7]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C408(1.07)  LDD2090  [7]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C408(1.04)  LDD2092  [7]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C408(1.02)  LDD2093  [7]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C408(1.42)  LDD2094  [7]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C408(0.74)  LDD2097  [7]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C408(0.60)  LDD2098  [7]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C408(0.77)  LDD2099  [7]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C408(0.29); C273(0.43)  LDD2100  [7]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C284(0.90); C273(0.55)  LDD2104  [7]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C408(1.75)  LDD2105  [7]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C284(0.94)  LDD2107  [7]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C408(0.26)  LDD2108  [7]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C408(1.08)  LDD2109  [7]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C408(0.71)  LDD2111  [7]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C408(0.51)  LDD2115  [7]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C408(0.42)  LDD2116  [7]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C408(0.45)  LDD2118  [7]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C408(1.32)  LDD2119  [7]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C408(0.77)  LDD2120  [7]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C408(0.22)  LDD2122  [7]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C284(0.76)  LDD2123  [7]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C408(0.24); C284(0.75)  LDD2124  [7]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C408(0.54)  LDD2125  [7]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C408(1.52)  LDD2127  [7]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C408(0.97)  LDD2128  [7]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C408(0.98)  LDD2129  [7]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C408(0.70)  LDD2133  [7]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C408(0.80)  LDD2134  [7]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C408(1.00)  LDD2135  [7]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C408(1.25)  LDD2136  [7]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C284(1.89); C273(1.00)  LDD2137  [7]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C408(0.99)  LDD1700  [7]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C408(0.80)  LDD2140  [7]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C273(0.39)  LDD2141  [7]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C408(0.92)  LDD2143  [7]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C408(1.31)  LDD2144  [7]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C273(1.05)  LDD2146  [7]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C408(2.38)  LDD2147  [7]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C408(0.61)  LDD2148  [7]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C408(0.38)  LDD2149  [7]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C408(0.41)  LDD2151  [7]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C408(1.74)  LDD2153  [7]
 LDCM0627  NUDT7-COV-1 HEK-293T C408(0.79)  LDD2206  [34]
 LDCM0628  OTUB2-COV-1 HEK-293T C408(0.39); C261(0.26)  LDD2207  [34]
 LDCM0014  Panhematin K562 3.07  LDD0063  [9]
 LDCM0131  RA190 MM1.R C261(2.36)  LDD0304  [35]
 LDCM0096  SAHA K562 20.00  LDD0269  [6]
 LDCM0021  THZ1 HCT 116 C273(1.19); C408(1.11)  LDD2173  [13]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
PR domain zinc finger protein 5 (PRDM5) Class V-like SAM-binding methyltransferase superfamily Q9NQX1
Histone-lysine N-methyltransferase EHMT2 (EHMT2) Histone-lysine methyltransferase family Q96KQ7
Histone-lysine N-methyltransferase SUV39H1 (SUV39H1) Histone-lysine methyltransferase family O43463
Probable ATP-dependent RNA helicase DDX5 (DDX5) DEAD box helicase family P17844
Histone deacetylase 2 (HDAC2) Histone deacetylase family Q92769
Casein kinase II subunit alpha (CSNK2A1) Ser/Thr protein kinase family P68400
Chromodomain-helicase-DNA-binding protein 4 (CHD4) SNF2/RAD54 helicase family Q14839
PWWP domain-containing protein 2A (PWWP2A) . Q96N64
Transcription factor E4F1 (E4F1) . Q66K89
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cellular tumor antigen p53 (TP53) P53 family P04637
Histone deacetylase complex subunit SAP18 (SAP18) SAP18 family O00422
Transcription factor
Click To Hide/Show 19 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
AT-rich interactive domain-containing protein 5B (ARID5B) ARID5B family Q14865
REST corepressor 1 (RCOR1) CoREST family Q9UKL0
Transcription factor E2F1 (E2F1) E2F/DP family Q01094
Zinc finger and BTB domain-containing protein 16 (ZBTB16) Krueppel C2H2-type zinc-finger protein family Q05516
Zinc finger protein 516 (ZNF516) Krueppel C2H2-type zinc-finger protein family Q92618
Nuclear receptor corepressor 2 (NCOR2) N-CoR nuclear receptor corepressors family Q9Y618
Nuclear receptor subfamily 0 group B member 2 (NR0B2) Nuclear hormone receptor family Q15466
Zinc finger protein SNAI1 (SNAI1) Snail C2H2-type zinc-finger protein family O95863
Transcription factor Sp1 (SP1) Sp1 C2H2-type zinc-finger protein family P08047
B-cell lymphoma/leukemia 11B (BCL11B) . Q9C0K0
DNA (cytosine-5)-methyltransferase 3-like (DNMT3L) . Q9UJW3
Mesoderm induction early response protein 1 (MIER1) . Q8N108
Metastasis-associated protein MTA1 (MTA1) . Q13330
Metastasis-associated protein MTA2 (MTA2) . O94776
Methyl-CpG-binding domain protein 1 (MBD1) . Q9UIS9
Nuclear factor NF-kappa-B p105 subunit (NFKB1) . P19838
Transcription factor p65 (RELA) . Q04206
Zinc finger and BTB domain-containing protein 7A (ZBTB7A) . O95365
Zinc finger protein Gfi-1 (GFI1) . Q99684
Other
Click To Hide/Show 15 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Breast cancer metastasis-suppressor 1 (BRMS1) BRMS1 family Q9HCU9
Death domain-associated protein 6 (DAXX) DAXX family Q9UER7
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) Histone H4 family P62805
Nucleophosmin (NPM1) Nucleoplasmin family P06748
Retinoblastoma-associated protein (RB1) Retinoblastoma protein (RB) family P06400
SIN3-HDAC complex-associated factor (SINHCAF) SINHCAF family Q9NP50
UPF0547 protein C16orf87 (C16orf87) UPF0547 family Q6PH81
Histone-binding protein RBBP4 (RBBP4) WD repeat RBAP46/RBAP48/MSI1 family Q09028
Histone-binding protein RBBP7 (RBBP7) WD repeat RBAP46/RBAP48/MSI1 family Q16576
EP300-interacting inhibitor of differentiation 2B (EID2B) . Q96D98
G protein pathway suppressor 2 (GPS2) . Q13227
Host cell factor 1 (HCFC1) . P51610
Melanoma-associated antigen 1 (MAGEA1) . P43355
Methyl-CpG-binding domain protein 3 (MBD3) . O95983
Paired amphipathic helix protein Sin3a (SIN3A) . Q96ST3

The Drug(s) Related To This Target

Approved
Click To Hide/Show 13 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Arsenic Trioxide Small molecular drug DB01169
Decitabine Small molecular drug DB01262
Fingolimod Small molecular drug DB08868
Panobinostat Small molecular drug D0E3SH
Phenylbutyric Acid Small molecular drug DB06819
Propanoic Acid Small molecular drug DB03766
Romidepsin Small molecular drug D0L7LC
Valproic Acid Small molecular drug DB00313
Vorinostat Small molecular drug D0E7PQ
Zinc . DB01593
Zinc Acetate . DB14487
Zinc Chloride . DB14533
Zinc Sulfate Unspecified Form . DB14548
Phase 3
Click To Hide/Show 3 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Itf2357 Small molecular drug D0GH3Q
Nvp-laq824 Small molecular drug D0B3FV
Sndx-275 Small molecular drug D0M8FD
Phase 2
Click To Hide/Show 6 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Chr-3996 Small molecular drug D06TKI
Mgcd-0103 Small molecular drug D00FHR
Phenylbutyrate Small molecular drug D0B7CH
Resminostat Small molecular drug D01UXJ
Sb-623 Small molecular drug D0VE1W
Sodium Butyrate Small molecular drug D0I7IB
Phase 1
Click To Hide/Show 3 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Rg-2833 Small molecular drug D0GE5B
Sb-639 Small molecular drug D07FPY
Obp-801 . D00SSZ
Clinical trial
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Hbi-8000 Small molecular drug D00SQN
Preclinical
Click To Hide/Show 8 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
4sc-202 Small molecular drug D0L5DZ
Chlamydocin Small molecular drug D0UC6H
Depudecin Small molecular drug D0W8JE
Hc-toxin Small molecular drug D06RQU
M-carboxycinnamic Acid Bishydroxamide Small molecular drug D03SZR
Scriptaid Small molecular drug D0J8OC
Sk-7041 Small molecular drug D0UL5X
Sk-7068 Small molecular drug D0DO5U
Investigative
Click To Hide/Show 149 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
(E)-8-biphenyl-4-yl-1-oxazol-2-yl-oct-7-en-1-one Small molecular drug D0KE3I
1,1,1-trifluoro-8-(4-phenoxy-phenoxy)-octan-2-one Small molecular drug D06BKA
1,1,1-trifluoro-8-phenoxy-octan-2-one Small molecular drug D04ETX
2-(Methylsulfonylthio)Ethyl 2-propylpentanoate Small molecular drug D0H1FZ
4-benzenesulfonylamino-n-hydroxy-benzamide Small molecular drug D02VVU
4-benzoylamino-n-hydroxy-benzamide Small molecular drug D09ZNU
4-butyrylamino-n-hydroxy-benzamide Small molecular drug D05LLX
4-chloro-n-(5-hydroxycarbamoyl-pentyl)-benzamide Small molecular drug D0A5LS
4-dimethylamino-n-(6-mercapto-hexyl)-benzamide Small molecular drug D06XNP
4-hydroxy-n-(5-hydroxycarbamoyl-pentyl)-benzamide Small molecular drug D04NSP
4-phenylbutyrohydroxamic Acid Small molecular drug D02NWS
4-tert-butyl-n-hydroxybenzamide Small molecular drug D03FOD
5-(4-chloro-phenyl)-pentanoic Acid Hydroxyamide Small molecular drug D0V2ZO
5-(4-hydroxyphenyl)-3h-1,2-dithiole-3-thione Small molecular drug D06IQB
5-mercapto-pentanoic Acid Phenylamide Small molecular drug D0D2KE
6-(2-bromo-acetylamino)-hexanoic Acid Phenylamide Small molecular drug D02MQM
6-(3-benzoyl-ureido)-hexanoic Acid Hydroxyamide Small molecular drug D00GBB
6-(9h-carbazol-9-yl)-n-hydroxyhexanamide Small molecular drug D06FAK
6-benzenesulfinylhexanoic Acid Hydroxamide Small molecular drug D00ZSD
6-benzenesulfonylhexanoic Acid Hydroxamide Small molecular drug D05AHZ
6-mercapto-hexanoic Acid Phenylamide Small molecular drug D0B3ZM
6-phenoxy-hexane-1-thiol Small molecular drug D09YBN
6-phenylsulfanylhexanoic Acid Hydroxamide Small molecular drug D0S9JF
7-(1h-indol-5-yloxy)-n-hydroxyheptanamide Small molecular drug D0G0OF
7-(3-benzoyl-ureido)-heptanoic Acid Hydroxyamide Small molecular drug D0T0BE
7-(4-(Dimethylamino)Phenoxy)-n-hydroxyheptanamide Small molecular drug D07HUH
7-(Biphenyl-3-yloxy)-1-oxazol-2-yl-heptan-1-one Small molecular drug D0B2ZJ
7-(Biphenyl-4-yloxy)-1,1,1-trifluoro-heptan-2-one Small molecular drug D0Z3BM
7-(Biphenyl-4-yloxy)-1-oxazol-2-yl-heptan-1-one Small molecular drug D02WZK
7-(Biphenyl-4-yloxy)-heptanoic Acid Hydroxyamide Small molecular drug D04LLD
7-(Naphthalen-2-yloxy)-1-oxazol-2-yl-heptan-1-one Small molecular drug D05VFP
7-biphenyl-4-yl-heptanoic Acid Hydroxyamide Small molecular drug D01RJY
7-mercapto-heptanoic Acid Benzothiazol-2-ylamide Small molecular drug D0Z5KX
7-mercapto-heptanoic Acid Biphenyl-3-ylamide Small molecular drug D05XAN
7-mercapto-heptanoic Acid Biphenyl-4-ylamide Small molecular drug D01XWZ
7-mercapto-heptanoic Acid Phenylamide Small molecular drug D00SEE
7-mercapto-heptanoic Acid Pyridin-3-ylamide Small molecular drug D07FJU
7-mercapto-heptanoic Acid Quinolin-3-ylamide Small molecular drug D0T4IY
7-mercapto-n-(4-phenylthiazol-2-yl)Heptanamide Small molecular drug D02HVH
7-phenoxy-heptanoic Acid Hydroxyamide Small molecular drug D05ZGM
8-(3-benzoyl-ureido)-octanoic Acid Hydroxyamide Small molecular drug D03ZUZ
8-(4-bromophenyl)-n-hydroxy-8-oxooctanamide Small molecular drug D0GJ1E
8-(Biphenyl-3-yloxy)-1,1,1-trifluoro-octan-2-one Small molecular drug D0NL6C
8-(Biphenyl-4-yl)-n-hydroxy-8-oxooctanamide Small molecular drug D0A6CB
8-(Biphenyl-4-yloxy)-1,1,1-trifluoro-octan-2-one Small molecular drug D0AX7B
8-(Biphenyl-4-yloxy)-2-oxo-octanoic Acid Small molecular drug D03XXI
8-mercapto-octanoic Acid Phenylamide Small molecular drug D0XZ9Q
8-oxo-8-phenyl-octanoic Acid Small molecular drug D0RU1X
8-oxo-8-phenyl-octanoic Acid Hydroxyamide Small molecular drug D0S0WK
8-phenyl-octanoic Acid Hydroxyamide Small molecular drug D0H9DS
9,9,9-trifluoro-8-oxo-nonanoic Acid Phenylamide Small molecular drug D00KFF
9-(Biphenyl-4-yloxy)-1,1,1-trifluoro-nonan-2-one Small molecular drug D05FEJ
Abexinostat Small molecular drug DB12565
Ads-100380 Small molecular drug D0Q8QA
Ads-102550 Small molecular drug D0M0QJ
Azumamide B Small molecular drug D0M1ZI
Azumamide C Small molecular drug D0Q9PO
Azumamide E Small molecular drug D0E9DD
Cyclo(-l-am7(S2py)-a2in-l-ala-d-pro-) Small molecular drug D02NVY
Cyclo(-l-am7(S2py)-aib-l-ala-d-pro-) Small molecular drug D0R3XO
Cyclo(-l-am7(S2py)-aib-l-ala-d-tic-) Small molecular drug D0N5RV
Cyclo(-l-am7(S2py)-aib-l-ph4-d-pro-) Small molecular drug D0X4QC
Cyclo(-l-am7(S2py)-aib-l-ph5-d-pro-) Small molecular drug D03PRG
Cyclo(-l-am7(S2py)-aib-l-phe-d-pro-) Small molecular drug D0Z6MI
Cyclo(-l-am7(S2py)-aib-l-phg-d-pro-) Small molecular drug D0G1EX
Cyclo(-l-am7(S2py)-aib-l-ser(Bzl)-d-pro-) Small molecular drug D0E8UH
Cyclo(-l-am7(S2py)-aib-l-ser-d-pro-) Small molecular drug D0U0EZ
Cyclo(-l-am7(S2py)-d-2mephe-l-ala-d-pro-) Small molecular drug D04CDZ
Cyclo(-l-am7(S2py)-d-a1in-l-ala-d-pro-) Small molecular drug D02NAF
Cyclo(-l-am7(S2py)-l-2mephe-l-ala-d-pro-) Small molecular drug D0Z6HR
Cyclo(-l-am7(S2py)-l-a1in-l-ala-d-pro-) Small molecular drug D00XTC
Cyclostellettamine Derivative Small molecular drug D0C0VP
Desclasinose Azithromycinarylalkyl Hydroxamate Small molecular drug D06THS
Gymnochrome E Small molecular drug D0B1YM
Largazole Small molecular drug D0Z8PX
Mocetinostat Small molecular drug DB11830
N,8-dihydroxy-8-(Naphthalen-2-yl)Octanamide Small molecular drug D00LSZ
N-(2,3-dimethylphenyl)-n'-hydroxyoctanediamide Small molecular drug D01AMS
N-(2,4-dimethylphenyl)-n'-hydroxyoctanediamide Small molecular drug D05GRZ
N-(2,5-dimethylphenyl)-n'-hydroxyoctanediamide Small molecular drug D0B8RC
N-(2,6-dimethylphenyl)-n'-hydroxyoctanediamide Small molecular drug D0SQ1F
N-(2-amino-5-(Thiophen-2-yl)Phenyl)Nicotinamide Small molecular drug D0Q2GM
N-(2-aminophenyl)-4-(Chroman-3-ylmethyl)Benzamide Small molecular drug D0P1RQ
N-(2-aminophenyl)-4-methoxybenzamide Small molecular drug D0YO6M
N-(2-aminophenyl)Nicotinamide Small molecular drug D04UVL
N-(2-aminophenyl)Quinoxaline-6-carboxamide Small molecular drug D01FYB
N-(2-ethylphenyl)-n'-hydroxyoctanediamide Small molecular drug D01ZMJ
N-(2-mercapto-ethyl)-n'-phenyl-oxalamide Small molecular drug D0F0KS
N-(2-mercapto-ethyl)-n'-phenyl-succinamide Small molecular drug D01MFV
N-(3,4-dimethylphenyl)-n'-hydroxyoctanediamide Small molecular drug D0L5KP
N-(3,5-dimethylphenyl)-n'-hydroxyoctanediamide Small molecular drug D08TIJ
N-(3-ethylphenyl)-n'-hydroxyoctanediamide Small molecular drug D0J3CY
N-(4-aminobiphenyl-3-yl)Nicotinamide Small molecular drug D0M9LJ
N-(4-ethylphenyl)-n'-hydroxyoctanediamide Small molecular drug D08ICY
N-(4-hydroxybiphenyl-3-yl)Benzamide Small molecular drug D0E0TA
N-(5-hydroxycarbamoyl-pentyl)-4-nitro-benzamide Small molecular drug D0C2KD
N-(6-hydroxycarbamoyl-hexyl)-benzamide Small molecular drug D0YY9M
N-(6-mercapto-hexyl)-benzamide Small molecular drug D04HSS
N-hydroxy-2,2'-bithiophene-5-carboxamide Small molecular drug D0PP3Q
N-hydroxy-4-((R)-2-phenyl-butyrylamino)-benzamide Small molecular drug D04ZDI
N-hydroxy-4-((S)-2-phenyl-butyrylamino)-benzamide Small molecular drug D0QO0L
N-hydroxy-4-(2-phenyl-butyrylamino)-benzamide Small molecular drug D06VBN
N-hydroxy-4-(4-phenyl-butyrylamino)-benzamide Small molecular drug D0S7WQ
N-hydroxy-4-(5-phenyl-pentanoylamino)-benzamide Small molecular drug D0R5VG
N-hydroxy-4-(Pentanoylamino-methyl)-benzamide Small molecular drug D0Z7YS
N-hydroxy-4-(Phenylacetylamino-methyl)-benzamide Small molecular drug D02UTC
N-hydroxy-4-phenylacetylamino-benzamide Small molecular drug D01XXN
N-hydroxy-5-(Pyridin-2-yl)Thiophene-2-carboxamide Small molecular drug D05PYF
N-hydroxy-5-(Pyridin-3-yl)Thiophene-2-carboxamide Small molecular drug D00PLM
N-hydroxy-5-(Pyridin-4-yl)Thiophene-2-carboxamide Small molecular drug D0A7IF
N-hydroxy-5-phenylthiophene-2-carboxamide Small molecular drug D06NVX
N-hydroxy-6-oxo-6-phenylhexanamide Small molecular drug D0L4ML
N-hydroxy-7-(4-methoxyphenyl)-7-oxoheptanamide Small molecular drug D0K8MF
N-hydroxy-7-(Naphthalen-2-yl)-7-oxoheptanamide Small molecular drug D03FFI
N-hydroxy-7-(Naphthalen-2-yloxy)Heptanamide Small molecular drug D03OYL
N-hydroxy-7-oxo-7-phenylheptanamide Small molecular drug D0QX6R
N-hydroxy-8-(2-methoxyphenyl)-8-oxooctanamide Small molecular drug D0KM7H
N-hydroxy-8-(4-methoxyphenyl)-8-oxooctanamide Small molecular drug D0O7UF
N-hydroxy-8-(Naphthalen-2-yl)Non-8-enamide Small molecular drug D04XPZ
N-hydroxy-8-(Naphthalen-2-yl)Oct-7-enamide Small molecular drug D0CJ7L
N-hydroxy-8-(Naphthalen-2-yl)Octanamide Small molecular drug D0L5WI
N-hydroxy-8-oxo-8-(Pyridin-3-yl)Octanamide Small molecular drug D00RGD
N-hydroxy-9-oxo-9-phenylnonanamide Small molecular drug D0Z2VP
N-hydroxy-n'-(2-methylphenyl)Octanediamide Small molecular drug D0Q2CC
N-hydroxy-n'-(3-methylphenyl)Octanediamide Small molecular drug D0H7QA
N-hydroxy-n'-(4-methoxyphenyl)Octanediamide Small molecular drug D0L6YF
N-hydroxy-n'-(4-methylphenyl)Octanediamide Small molecular drug D00HFS
N-hydroxybenzo[B]Thiophene-2-carboxamide Small molecular drug D0D3XC
N1-(Biphenyl-3-yl)-n8-hydroxyoctanediamide Small molecular drug D08XMS
N1-(Biphenyl-4-yl)-n8-hydroxyoctanediamide Small molecular drug D04DOL
N1-hydroxy-n8-(4-phenylthiazol-2-yl)Octanediamide Small molecular drug D0YP4F
Nexturastat A Small molecular drug D0Q5DI
Nsc-746457 Small molecular drug D01EDB
Octanedioic Acid Bis-hydroxyamide Small molecular drug D07YZZ
Octanedioic Acid Hydroxyamide Pyridin-2-ylamide Small molecular drug D0E8KR
Octanedioic Acid Hydroxyamide Pyridin-4-ylamide Small molecular drug D04GGW
Pracinostat Small molecular drug DB05223
Psammaplin A Small molecular drug D0N0TS
Sk-683 Small molecular drug D0U3MB
St-2986 Small molecular drug D0N9AK
St-2987 Small molecular drug D0T0SK
St-3050 Small molecular drug D01YBR
Thioacetic Acid S-(6-phenylcarbamoyl-hexyl) Ester Small molecular drug D05GVY
Azithromycin-n-benzyltriazolyldecahydroxamic Acid . D06ONC
Azithromycin-n-benzyltriazolylhexahydroxamic Acid . D0I5XM
Azithromycin-n-benzyltriazolylnonahydroxamic Acid . D0H3RO
Azithromycin-n-benzyltriazolyloctahydroxamic Acid . D0D7KH
Azithromycinarylalkylhydroxamic Acid . D0P9CQ
N-hydroxy-4-(3-phenyl-propionylamino)-benzamide . D0R4BS
Patented
Click To Hide/Show 76 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Diaryl Amine Derivative 2 Small molecular drug D0S7NE
Diaryl Amine Derivative 3 Small molecular drug D0KA3X
Isosteric Imidazolyl Pyrimidine Derivative 1 Small molecular drug D0QR1Z
Pmid28092474-compound-32a Small molecular drug D00XWZ
Pmid28092474-compound-32b Small molecular drug D04VQE
Pmid28092474-compound-32c Small molecular drug D0DH7R
Pmid28092474-compound-32d Small molecular drug D0N1RX
Pmid28092474-compound-32e Small molecular drug D0M7XL
Pmid28092474-compound-32f Small molecular drug D0S3ZB
Pmid28092474-compound-32g Small molecular drug D03EUD
Pmid28092474-compound-32h Small molecular drug D0EU5A
Pmid28092474-compound-32i Small molecular drug D0SK9K
Pmid28092474-compound-32j Small molecular drug D01LCZ
Pmid28092474-compound-32k Small molecular drug D0QF0Y
Pmid28092474-compound-32l Small molecular drug D0W1AX
Pmid28092474-compound-32m Small molecular drug D0MQ2D
Pmid28092474-compound-32n Small molecular drug D0O6SJ
Pmid28092474-compound-32o Small molecular drug D06IIL
Pmid28092474-compound-32p Small molecular drug D0MR7U
Pmid28092474-compound-32q Small molecular drug D0TH3L
Pmid28092474-compound-32r Small molecular drug D0ET4U
Pmid28092474-compound-32s Small molecular drug D0YC2M
Pmid28092474-compound-32t Small molecular drug D0CX1Y
Pmid28092474-compound-32u Small molecular drug D00GLJ
Pmid28092474-compound-32v Small molecular drug D08ZJZ
Pmid28092474-compound-32x Small molecular drug D04KQU
Pmid28092474-compound-32y Small molecular drug D0HM6Y
Pmid28092474-compound-32z Small molecular drug D02YDG
Pmid28092474-compound-33a Small molecular drug D00LLN
Pmid28092474-compound-33b Small molecular drug D04MVN
Pmid28092474-compound-33c Small molecular drug D0L3CU
Pmid28092474-compound-33d Small molecular drug D00ACL
Pmid28092474-compound-33e Small molecular drug D0CH4M
Pmid28092474-compound-33f Small molecular drug D0K2UF
Pmid28092474-compound-33g Small molecular drug D08GBR
Pmid28092474-compound-33h Small molecular drug D0JN0A
Pmid28092474-compound-33i Small molecular drug D0E5CO
Pmid28092474-compound-33j Small molecular drug D08GQL
Pmid28092474-compound-33k Small molecular drug D0Q9XK
Pmid28092474-compound-33l Small molecular drug D0SF8N
Pmid28092474-compound-33m Small molecular drug D08XLK
Pmid28092474-compound-33o Small molecular drug D0RD7T
Pmid28092474-compound-33p Small molecular drug D08SNJ
Pmid28092474-compound-34a Small molecular drug D0QN8W
Pmid28092474-compound-34b Small molecular drug D0BY1R
Pmid28092474-compound-34c Small molecular drug D04AMI
Pmid29671355-compound-11 Small molecular drug D0EH2K
Pmid29671355-compound-13 Small molecular drug D0ZG5X
Pmid29671355-compound-18 Small molecular drug D0TN6E
Pmid29671355-compound-19 Small molecular drug D0LV6K
Pmid29671355-compound-21 Small molecular drug D0LP1K
Pmid29671355-compound-22 Small molecular drug D0QX3G
Pmid29671355-compound-23 Small molecular drug D00HXJ
Pmid29671355-compound-24 Small molecular drug D09PVH
Pmid29671355-compound-25 Small molecular drug D0RA0D
Pmid29671355-compound-26 Small molecular drug D0R3RJ
Pmid29671355-compound-27 Small molecular drug D0V5IQ
Pmid29671355-compound-28 Small molecular drug D0Z7QI
Pmid29671355-compound-31 Small molecular drug D0DI9S
Pmid29671355-compound-38a Small molecular drug D0JR9L
Pmid29671355-compound-38b Small molecular drug D0YD7B
Pmid29671355-compound-39 Small molecular drug D0L7HG
Pmid29671355-compound-42 Small molecular drug D0YT8O
Pmid29671355-compound-43 Small molecular drug D0BP8I
Pmid29671355-compound-44 Small molecular drug D0N2DK
Pmid29671355-compound-55 Small molecular drug D0OU0J
Pmid29671355-compound-56 Small molecular drug D0CH8Q
Pmid29671355-compound-57 Small molecular drug D0UD9R
Pmid29671355-compound-59 Small molecular drug D0C9NX
Pmid29671355-compound-61 Small molecular drug D0JB4S
Pmid29671355-compound-62 Small molecular drug D07WAT
Pmid29671355-compound-65a Small molecular drug D0F3TB
Pmid29671355-compound-67 Small molecular drug D0M0RE
Pmid29671355-compound-73 Small molecular drug D0T7OQ
Pmid29671355-compound-8 Small molecular drug D0LN1T
Pmid29671355-compound-9 Small molecular drug D0Q1QY
Discontinued
Click To Hide/Show 4 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
An-9 Small molecular drug D0MP2U
Oxamflatin Small molecular drug D03YVR
Pyroxamide Small molecular drug D0N3SH
Tacedinaline Small molecular drug D0W9NH

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Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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