Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0557
Competitor Name
Nucleophilic fragment 8b
Synonyms
N-((3s,5s,7s)-adamantan-1-yl)-2-nitroacetamide
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 238.28
Lipid-water partition coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C12H18N2O3
IUPAC Name
N-(1-adamantyl)-2-nitroacetamide
Canonical SMILES
C1C2CC3CC1CC(C2)(C3)NC(=O)C[N+](=O)[O-]
InChI
InChI=1S/C12H18N2O3/c15-11(7-14(16)17)13-12-4-8-1-9(5-12)3-10(2-8)6-12/h8-10H,1-7H2,(H,13,15)
InChIKey
HXPWFSGCDRNCEO-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
BTD
 Probe Info  		5 mM Human breast adenocarcinoma cell lysate (MDA-MB-231) [1]

Target(s) List of this Competitor

289 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) LDTP02984 0.97  LDD2151 
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 0.59  LDD2151 
2',5'-phosphodiesterase 12 (PDE12) LDTP07447 1.49  LDD2151 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 0.84  LDD2151 
2-iminobutanoate/2-iminopropanoate deaminase (RIDA) LDTP04529 0.43  LDD2151 
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) LDTP10869 0.47  LDD2151 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 0.33; 1.09  LDD2151 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 1.33; 0.32  LDD2151 
26S proteasome non-ATPase regulatory subunit 4 (PSMD4) LDTP04655 0.19  LDD2151 
26S proteasome non-ATPase regulatory subunit 8 (PSMD8) LDTP04196 0.39  LDD2151 
26S proteasome non-ATPase regulatory subunit 9 (PSMD9) LDTP00225 0.40  LDD2151 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 0.20  LDD2151 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 0.45  LDD2151 
26S proteasome regulatory subunit 6A (PSMC3) LDTP02933 0.20  LDD2151 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 1.11  LDD2151 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 0.27  LDD2151 
3-ketoacyl-CoA thiolase, mitochondrial (ACAA2) LDTP03998 0.50  LDD2151 
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) LDTP02329 0.83  LDD2151 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 0.38  LDD2151 
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) LDTP04232 0.16  LDD2151 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.93  LDD2151 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 4.21; 0.54  LDD2151 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 1.31  LDD2151 
Aconitate hydratase, mitochondrial (ACO2) LDTP10982 0.35; 0.37  LDD2151 
Adenosine 5'-monophosphoramidase HINT1 (HINT1) LDTP04306 0.39  LDD2151 
Adenosylhomocysteinase (AHCY) LDTP03242 0.36; 1.07; 0.37  LDD2151 
Adenylosuccinate lyase (ADSL) LDTP03551 0.35  LDD2151 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 0.35  LDD2151 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 0.36  LDD2151 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 1.65; 0.39; 0.09  LDD2151 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 0.30; 0.14  LDD2151 
Alpha-enolase (ENO1) LDTP02159 0.39  LDD2151 
Aminoacylase-1 (ACY1) LDTP05395 0.43  LDD2151 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 0.36  LDD2151 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 1.46  LDD2151 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 0.66  LDD2151 
Aspartate aminotransferase, mitochondrial (GOT2) LDTP01783 0.12  LDD2151 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 0.39  LDD2151 
ATP-citrate synthase (ACLY) LDTP04561 1.26  LDD2151 
ATP-dependent RNA helicase A (DHX9) LDTP05550 0.26; 0.16; 0.42  LDD2151 
ATP-dependent RNA helicase DDX39A (DDX39A) LDTP00192 1.10; 1.43  LDD2151 
ATP-dependent RNA helicase DDX3X (DDX3X) LDTP00314 0.94; 0.89  LDD2151 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 0.30  LDD2151 
ATP-dependent RNA helicase DHX30 (DHX30) LDTP07946 0.98  LDD2151 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 0.59  LDD2151 
Aurora kinase A (AURKA) LDTP00491 1.36  LDD2151 
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (BNIP2) LDTP05716 0.96  LDD2151 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 1.02; 1.59  LDD2151 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 0.28; 0.25; 0.60  LDD2151 
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (NUDT2) LDTP04376 1.63  LDD2151 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 0.51  LDD2151 
Calcyclin-binding protein (CACYBP) LDTP12163 2.01  LDD2151 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 0.36; 0.99; 0.60 ...  LDD2151 
cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) LDTP02909 0.55  LDD2151 
Carboxymethylenebutenolidase homolog (CMBL) LDTP10215 0.38; 0.35  LDD2151 
Caspase-8 (CASP8) LDTP06211 0.59  LDD2151 
Catalase (CAT) LDTP02001 0.12  LDD2151 
Cell division control protein 42 homolog (CDC42) LDTP04886 0.42  LDD2151 
CTP synthase 1 (CTPS1) LDTP02922 11.58  LDD2151 
Cullin-1 (CUL1) LDTP05946 0.37  LDD2151 
Cullin-2 (CUL2) LDTP05947 0.36; 0.20  LDD2151 
Cullin-4B (CUL4B) LDTP05950 1.24; 0.32  LDD2151 
Cullin-associated NEDD8-dissociated protein 1 (CAND1) LDTP08296 0.12  LDD2151 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 2.86  LDD2151 
Cytoplasmic aconitate hydratase (ACO1) LDTP03110 0.80  LDD2151 
Cytosol aminopeptidase (LAP3) LDTP03455 0.11; 0.58  LDD2151 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 0.65; 0.77  LDD2151 
Cytosolic non-specific dipeptidase (CNDP2) LDTP10514 0.98  LDD2151 
D-dopachrome decarboxylase (DDT) LDTP03513 0.27  LDD2151 
Deoxycytidylate deaminase (DCTD) LDTP03643 0.58; 0.89  LDD2151 
Deoxyribose-phosphate aldolase (DERA) LDTP13941 0.38  LDD2151 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 0.38  LDD2151 
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT) LDTP02497 0.18  LDD2151 
Dihydropteridine reductase (QDPR) LDTP02342 0.40  LDD2151 
Dihydroxyacetone phosphate acyltransferase (GNPAT) LDTP00577 7.03  LDD2151 
Dipeptidyl peptidase 9 (DPP9) LDTP08198 0.39  LDD2151 
Diphosphomevalonate decarboxylase (MVD) LDTP04567 0.91  LDD2151 
DNA (cytosine-5)-methyltransferase 1 (DNMT1) LDTP03350 1.35; 0.46  LDD2151 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 1.17  LDD2151 
DNA repair protein RAD50 (RAD50) LDTP09912 0.60  LDD2151 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 1.07  LDD2151 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 1.18; 0.75  LDD2151 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 0.78  LDD2151 
DNA topoisomerase 1 (TOP1) LDTP02567 0.14; 0.18; 0.34 ...  LDD2151 
DNA topoisomerase 2-alpha (TOP2A) LDTP02568 0.23  LDD2151 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 1.56; 0.77; 0.45 ...  LDD2151 
Dolichol-phosphate mannosyltransferase subunit 1 (DPM1) LDTP01047 0.30  LDD2151 
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) LDTP04103 2.38  LDD2151 
Dynamin-1-like protein (DNM1L) LDTP00273 0.57  LDD2151 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 2.00  LDD2151 
E3 SUMO-protein ligase RanBP2 (RANBP2) LDTP04310 0.84; 0.55; 2.87  LDD2151 
E3 ubiquitin-protein ligase BRE1B (RNF40) LDTP01141 1.01  LDD2151 
E3 ubiquitin-protein ligase UBR5 (UBR5) LDTP01495 1.85  LDD2151 
Egl nine homolog 1 (EGLN1) LDTP11649 2.15  LDD2151 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 1.22  LDD2151 
Elongation factor 1-alpha 2 (EEF1A2) LDTP05460 0.55  LDD2151 
Elongation factor 2 (EEF2) LDTP02672 4.56; 0.75; 0.41 ...  LDD2151 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 1.36  LDD2151 
Estradiol 17-beta-dehydrogenase 11 (HSD17B11) LDTP09063 0.17  LDD2151 
Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) LDTP03915 0.28; 0.41  LDD2151 
Eukaryotic translation initiation factor 5B (EIF5B) LDTP01063 1.29; 0.48  LDD2151 
Exosome complex component 10 (EXOSC10) LDTP05312 2.36  LDD2151 
Exosome complex component RRP43 (EXOSC8) LDTP10110 1.62  LDD2151 
Exosome complex component RRP45 (EXOSC9) LDTP05482 0.07  LDD2151 
Glutathione S-transferase Mu 3 (GSTM3) LDTP03103 0.17  LDD2151 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.60  LDD2151 
Glutathione S-transferase P (GSTP1) LDTP02333 0.08; 0.37; 1.15  LDD2151 
Glutathione synthetase (GSS) LDTP04200 0.39; 0.42  LDD2151 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 3.56; 0.71  LDD2151 
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) LDTP04032 0.15  LDD2151 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.39; 0.44  LDD2151 
Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) LDTP03537 1.07  LDD2151 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 0.37  LDD2151 
GTP-binding nuclear protein Ran (RAN) LDTP05007 0.14  LDD2151 
H/ACA ribonucleoprotein complex subunit DKC1 (DKC1) LDTP01061 1.35  LDD2151 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 0.06  LDD2151 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.12; 0.18; 0.07  LDD2151 
Heme oxygenase 2 (HMOX2) LDTP03540 4.59  LDD2151 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 0.13  LDD2151 
Histone deacetylase 1 (HDAC1) LDTP05918 0.41  LDD2151 
Histone-arginine methyltransferase CARM1 (CARM1) LDTP08352 0.12  LDD2151 
Histone-lysine N-methyltransferase SETD7 (SETD7) LDTP09543 0.51  LDD2151 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 1.59  LDD2151 
Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) LDTP07762 2.56  LDD2151 
Immunity-related GTPase family Q protein (IRGQ) LDTP19838 1.16  LDD2151 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 1.64  LDD2151 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 0.09; 0.52  LDD2151 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 1.00  LDD2151 
Isoamyl acetate-hydrolyzing esterase 1 homolog (IAH1) LDTP17082 0.42  LDD2151 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 0.30  LDD2151 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 0.52  LDD2151 
Isoleucine--tRNA ligase, mitochondrial (IARS2) LDTP12588 1.05; 0.69  LDD2151 
Ketosamine-3-kinase (FN3KRP) LDTP16025 2.50  LDD2151 
Kinesin-like protein KIF14 (KIF14) LDTP06303 0.60  LDD2151 
Kinesin-like protein KIFC1 (KIFC1) LDTP11309 1.38  LDD2151 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 0.26  LDD2151 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 1.25  LDD2151 
Large ribosomal subunit protein mL44 (MRPL44) LDTP12098 1.88  LDD2151 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 0.99  LDD2151 
Lon protease homolog, mitochondrial (LONP1) LDTP03817 0.72  LDD2151 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 0.61  LDD2151 
Macrophage migration inhibitory factor (MIF) LDTP02713 2.42  LDD2151 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.03  LDD2151 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 0.69  LDD2151 
Minor histocompatibility antigen H13 (HM13) LDTP09396 0.71  LDD2151 
Mitochondrial Rho GTPase 2 (RHOT2) LDTP08596 0.14  LDD2151 
Molybdopterin synthase catalytic subunit (MOCS2) LDTP01747 0.27  LDD2151 
Multifunctional protein CAD (CAD) LDTP03401 0.43; 0.18  LDD2151 
Myosin-10 (MYH10) LDTP03765 0.30  LDD2151 
Myosin-9 (MYH9) LDTP03764 0.51; 0.56; 0.86 ...  LDD2151 
N-alpha-acetyltransferase 10 (NAA10) LDTP03938 2.36  LDD2151 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 0.59  LDD2151 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 0.38  LDD2151 
NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial (NDUFA10) LDTP01561 1.03  LDD2151 
NADH dehydrogenase 1 alpha subcomplex subunit 5 (NDUFA5) LDTP06614 1.02  LDD2151 
NADH dehydrogenase iron-sulfur protein 6, mitochondrial (NDUFS6) LDTP14493 0.05  LDD2151 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 0.60  LDD2151 
Neutral cholesterol ester hydrolase 1 (NCEH1) LDTP07591 4.80  LDD2151 
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT) LDTP06346 0.68  LDD2151 
Nitric oxide synthase-interacting protein (NOSIP) LDTP13940 0.88  LDD2151 
Nuclear pore complex protein Nup98-Nup96 (NUP98) LDTP04547 0.28  LDD2151 
Nucleolar GTP-binding protein 2 (GNL2) LDTP05987 1.48  LDD2151 
Nucleolar RNA helicase 2 (DDX21) LDTP12469 0.11  LDD2151 
Nucleoside diphosphate kinase B (NME2) LDTP03169 0.22  LDD2151 
Obg-like ATPase 1 (OLA1) LDTP12610 0.31; 0.89  LDD2151 
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) LDTP03813 0.75  LDD2151 
Pappalysin-2 (PAPPA2) LDTP11399 0.47  LDD2151 
Parkinson disease protein 7 (PARK7) LDTP10878 0.27  LDD2151 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 1.03; 0.14; 1.73 ...  LDD2151 
Peptidyl-prolyl cis-trans isomerase B (PPIB) LDTP03216 0.44  LDD2151 
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF) LDTP03534 0.21  LDD2151 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 0.71  LDD2151 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 0.47  LDD2151 
Peptidyl-prolyl cis-trans isomerase G (PPIG) LDTP05866 1.40  LDD2151 
Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2) LDTP13989 0.18  LDD2151 
Peroxiredoxin-1 (PRDX1) LDTP05503 1.22  LDD2151 
Peroxiredoxin-4 (PRDX4) LDTP05773 0.62  LDD2151 
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (DECR2) LDTP12627 0.53  LDD2151 
Peroxisomal acyl-coenzyme A oxidase 2 (ACOX2) LDTP10859 0.59  LDD2151 
Peroxisomal multifunctional enzyme type 2 (HSD17B4) LDTP04440 0.33  LDD2151 
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (INPPL1) LDTP00617 1.50  LDD2151 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 0.37; 0.44  LDD2151 
Phosphopentomutase (PGM2) LDTP10326 0.32; 0.64; 0.57  LDD2151 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 1.64; 0.47  LDD2151 
Poly [ADP-ribose] polymerase 1 (PARP1) LDTP02375 0.88; 1.19  LDD2151 
Presequence protease, mitochondrial (PITRM1) LDTP07003 1.00  LDD2151 
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (NOP2) LDTP04084 1.36  LDD2151 
Probable ATP-dependent RNA helicase DDX47 (DDX47) LDTP11730 0.13  LDD2151 
Probable ATP-dependent RNA helicase DDX5 (DDX5) LDTP02924 0.77; 1.31  LDD2151 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2) LDTP00285 1.42  LDD2151 
Proliferation-associated protein 2G4 (PA2G4) LDTP13750 0.13  LDD2151 
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) LDTP02095 0.43  LDD2151 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 3.65  LDD2151 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 0.50  LDD2151 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 0.24  LDD2151 
Proteasome subunit alpha type-3 (PSMA3) LDTP03332 0.05  LDD2151 
Proteasome subunit alpha type-4 (PSMA4) LDTP03333 0.45  LDD2151 
Proteasome subunit alpha type-5 (PSMA5) LDTP03413 0.43  LDD2151 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 0.28  LDD2151 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 0.09  LDD2151 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 0.32; 0.18  LDD2151 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 0.25; 1.08  LDD2151 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 0.27  LDD2151 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 0.34  LDD2151 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 0.34; 1.55  LDD2151 
Protein DDI1 homolog 2 (DDI2) LDTP07186 0.12  LDD2151 
Protein disulfide-isomerase (P4HB) LDTP02188 0.45; 0.09  LDD2151 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.65  LDD2151 
Protein phosphatase 1A (PPM1A) LDTP03788 0.39  LDD2151 
Protein phosphatase 3 catalytic subunit alpha (PPP3CA) LDTP05549 0.34  LDD2151 
Protein PML (PML) LDTP03496 2.09  LDD2151 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 0.45; 1.12; 0.53  LDD2151 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 0.08  LDD2151 
Pterin-4-alpha-carbinolamine dehydratase (PCBD1) LDTP04925 0.34  LDD2151 
Purine nucleoside phosphorylase (PNP) LDTP01781 0.34  LDD2151 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 0.52  LDD2151 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 1.68  LDD2151 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 0.84  LDD2151 
Pyruvate kinase PKM (PKM) LDTP02733 0.36; 0.43  LDD2151 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 0.92; 0.81  LDD2151 
Ras-related C3 botulinum toxin substrate 2 (RAC2) LDTP02768 0.80  LDD2151 
Ras-related protein Rab-14 (RAB14) LDTP04901 1.02  LDD2151 
Ras-related protein Rab-1A (RAB1A) LDTP05006 0.42  LDD2151 
Ras-related protein Rab-8A (RAB8A) LDTP04888 0.68  LDD2151 
Ras-related protein Rap-1b (RAP1B) LDTP04910 0.93  LDD2151 
Rho-associated protein kinase 2 (ROCK2) LDTP01127 1.03; 1.45  LDD2151 
Ribokinase (RBKS) LDTP11903 0.66  LDD2151 
Ribonucleases P/MRP protein subunit POP1 (POP1) LDTP10903 1.17  LDD2151 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 0.82  LDD2151 
Ribosomal oxygenase 2 (RIOX2) LDTP08451 1.08  LDD2151 
Ribosomal RNA small subunit methyltransferase NEP1 (EMG1) LDTP09951 1.19  LDD2151 
RNA cytidine acetyltransferase (NAT10) LDTP11690 0.77  LDD2151 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 0.70; 0.78  LDD2151 
S-formylglutathione hydrolase (ESD) LDTP02521 0.69  LDD2151 
S-phase kinase-associated protein 1 (SKP1) LDTP05052 1.57; 0.59  LDD2151 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 2.19; 0.51  LDD2151 
Secernin-1 (SCRN1) LDTP05640 0.15  LDD2151 
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) LDTP05183 1.11  LDD2151 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 0.60; 0.29; 0.20 ...  LDD2151 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 0.95  LDD2151 
Serine palmitoyltransferase 2 (SPTLC2) LDTP00598 1.15  LDD2151 
Serine/threonine-protein kinase VRK1 (VRK1) LDTP11030 1.13  LDD2151 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 0.29  LDD2151 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 1.16  LDD2151 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 0.64  LDD2151 
Sialic acid synthase (NANS) LDTP12473 1.20  LDD2151 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 0.99; 0.37; 0.27  LDD2151 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 0.19; 0.51; 0.80 ...  LDD2151 
Spermine synthase (SMS) LDTP04530 0.93  LDD2151 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 1.08; 0.20  LDD2151 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 0.54  LDD2151 
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL) LDTP06455 1.49  LDD2151 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 2.73  LDD2151 
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) LDTP03572 1.06  LDD2151 
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (OXCT1) LDTP04715 0.36  LDD2151 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 0.29  LDD2151 
SUMO-conjugating enzyme UBC9 (UBE2I) LDTP05062 0.47  LDD2151 
Synaptobrevin homolog YKT6 (YKT6) LDTP00654 0.40  LDD2151 
Telomerase RNA component interacting RNase (TRIR) LDTP11055 0.92  LDD2151 
Thimet oligopeptidase (THOP1) LDTP04542 0.36; 0.41  LDD2151 
Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 0.51  LDD2151 
Thioredoxin reductase 2, mitochondrial (TXNRD2) LDTP12297 0.96  LDD2151 
Threonylcarbamoyl-AMP synthase (YRDC) LDTP08217 0.74  LDD2151 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 0.71; 0.15; 0.38  LDD2151 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 0.91; 0.14  LDD2151 
Triosephosphate isomerase (TPI1) LDTP04851 0.27; 0.72; 0.16  LDD2151 
Tripeptidyl-peptidase 2 (TPP2) LDTP03469 0.87; 1.66  LDD2151 
Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) LDTP02935 1.15; 0.67  LDD2151 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 0.79  LDD2151 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 1.09  LDD2151 
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) LDTP04074 0.99; 1.62  LDD2151 
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCHL3) LDTP02783 2.55  LDD2151 
Ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1) LDTP05853 0.11  LDD2151 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 0.17; 0.94  LDD2151 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 0.45; 1.12; 1.14  LDD2151 
Ubiquitin-like-conjugating enzyme ATG3 (ATG3) LDTP12599 0.98  LDD2151 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 0.53  LDD2151 
UMP-CMP kinase (CMPK1) LDTP03519 1.76  LDD2151 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 1.54  LDD2151 
Utrophin (UTRN) LDTP04116 0.97  LDD2151 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 0.45  LDD2151 
V-type proton ATPase 116 kDa subunit a 3 (TCIRG1) LDTP05891 0.77  LDD2151 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 0.28  LDD2151 
Vacuolar protein sorting-associated protein 4A (VPS4A) LDTP13639 0.13  LDD2151 
Vacuolar protein sorting-associated protein 4B (VPS4B) LDTP01186 0.27  LDD2151 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 3.21  LDD2151 
X-ray repair cross-complementing protein 5 (XRCC5) LDTP02642 1.24; 0.67; 0.24  LDD2151 
Xaa-Arg dipeptidase (PM20D2) LDTP08666 2.24  LDD2151 
Xaa-Pro dipeptidase (PEPD) LDTP02639 0.36  LDD2151 
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⏷ Show the Full List of 289 Enzyme
78 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein theta (YWHAQ) LDTP03385 0.22; 0.16  LDD2151 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.19  LDD2151 
Annexin A1 (ANXA1) LDTP02010 0.42  LDD2151 
Annexin A6 (ANXA6) LDTP02247 0.32  LDD2151 
AP-1 complex subunit beta-1 (AP1B1) LDTP05625 1.00  LDD2151 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 0.08  LDD2151 
AP-2 complex subunit alpha-1 (AP2A1) LDTP01673 0.15; 0.35; 0.21  LDD2151 
Apoptosis regulator BAX (BAX) LDTP05528 0.14  LDD2151 
Apoptotic chromatin condensation inducer in the nucleus (ACIN1) LDTP13490 1.10; 0.43  LDD2151 
ATP synthase subunit gamma, mitochondrial (ATP5F1C) LDTP03810 0.37  LDD2151 
Calreticulin (CALR) LDTP03402 0.76  LDD2151 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 0.10  LDD2151 
Clathrin heavy chain 1 (CLTC) LDTP05252 1.01; 0.17; 2.15 ...  LDD2151 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 0.71  LDD2151 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 0.89  LDD2151 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 0.11  LDD2151 
Endoplasmic reticulum junction formation protein lunapark (LNPK) LDTP11609 2.35  LDD2151 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 0.98  LDD2151 
ER membrane protein complex subunit 6 (EMC6) LDTP11272 0.38  LDD2151 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 0.51  LDD2151 
Exportin-1 (XPO1) LDTP00501 0.60  LDD2151 
Exportin-2 (CSE1L) LDTP04662 1.03; 0.59; 0.74 ...  LDD2151 
Fatty acid-binding protein 5 (FABP5) LDTP05292 2.16  LDD2151 
Filamin-A (FLNA) LDTP03107 1.09; 0.28; 0.89 ...  LDD2151 
Filamin-B (FLNB) LDTP01197 1.44; 0.39  LDD2151 
Filamin-C (FLNC) LDTP06103 0.45; 1.04; 0.34 ...  LDD2151 
Galectin-3 (LGALS3) LDTP02929 2.76  LDD2151 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 0.10; 0.22  LDD2151 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 1.10  LDD2151 
Histone deacetylase complex subunit SAP18 (SAP18) LDTP00270 0.37  LDD2151 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 0.37; 0.84  LDD2151 
Importin subunit beta-1 (KPNB1) LDTP06242 0.26  LDD2151 
Importin-4 (IPO4) LDTP09515 0.17; 0.70; 0.39  LDD2151 
Importin-5 (IPO5) LDTP00266 0.47; 0.24; 0.11 ...  LDD2151 
Importin-7 (IPO7) LDTP01574 0.49; 0.34; 1.02  LDD2151 
Importin-9 (IPO9) LDTP10663 0.07  LDD2151 
Major vault protein (MVP) LDTP06203 0.20  LDD2151 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) LDTP13698 1.98  LDD2151 
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) LDTP05384 0.96  LDD2151 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 0.54  LDD2151 
Mitochondrial glutamate carrier 1 (SLC25A22) LDTP12078 0.56  LDD2151 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 1.22  LDD2151 
Myoferlin (MYOF) LDTP12916 0.76; 0.37; 0.35 ...  LDD2151 
Nuclear cap-binding protein subunit 1 (NCBP1) LDTP05591 1.47  LDD2151 
Nuclear pore complex protein Nup153 (NUP153) LDTP04309 1.04  LDD2151 
Nuclear pore complex protein Nup205 (NUP205) LDTP09825 1.76  LDD2151 
Nuclear pore complex protein Nup214 (NUP214) LDTP03777 1.25  LDD2151 
Nuclear pore complex protein Nup50 (NUP50) LDTP13498 2.66  LDD2151 
Nuclear pore complex protein Nup85 (NUP85) LDTP11310 1.00  LDD2151 
Nucleoporin NDC1 (NDC1) LDTP11213 4.03  LDD2151 
Nucleoprotein TPR (TPR) LDTP02612 0.96  LDD2151 
Podocalyxin (PODXL) LDTP00321 0.93  LDD2151 
Protein RFT1 homolog (RFT1) LDTP10073 0.57  LDD2151 
Protein S100-A10 (S100A10) LDTP04885 0.66  LDD2151 
Protein transport protein Sec31A (SEC31A) LDTP01478 0.62  LDD2151 
Protein transport protein Sec61 subunit gamma (SEC61G) LDTP04850 0.87  LDD2151 
Ran GTPase-activating protein 1 (RANGAP1) LDTP04082 0.42; 0.10  LDD2151 
Signal recognition particle 14 kDa protein (SRP14) LDTP03837 1.25  LDD2151 
Signal recognition particle subunit SRP68 (SRP68) LDTP13262 0.12  LDD2151 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 0.08; 0.69; 0.57  LDD2151 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 0.06  LDD2151 
Sorting nexin-12 (SNX12) LDTP13634 0.69  LDD2151 
Sorting nexin-5 (SNX5) LDTP14174 0.83  LDD2151 
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 0.12; 0.51  LDD2151 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 1.51  LDD2151 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.76; 0.69  LDD2151 
Talin-1 (TLN1) LDTP14031 0.11; 0.65; 0.26 ...  LDD2151 
THO complex subunit 7 homolog (THOC7) LDTP07397 1.62  LDD2151 
Translocation protein SEC63 homolog (SEC63) LDTP13243 0.94  LDD2151 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 0.20  LDD2151 
Transport and Golgi organization protein 1 homolog (MIA3) LDTP07002 0.99  LDD2151 
Transportin-3 (TNPO3) LDTP14133 1.01; 0.86  LDD2151 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 0.85  LDD2151 
Vacuolar protein sorting-associated protein 29 (VPS29) LDTP13142 0.40  LDD2151 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 0.76; 0.29  LDD2151 
Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 1.67; 0.97  LDD2151 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 1.42  LDD2151 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 0.70; 0.64; 4.94  LDD2151 
------------------------------------------------------------------------------------
⏷ Show the Full List of 78 Transporter and channel
13 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Cell division cycle 5-like protein (CDC5L) LDTP10868 1.32  LDD2151 
Dr1-associated corepressor (DRAP1) LDTP06229 1.09  LDD2151 
eIF5-mimic protein 1 (BZW2) LDTP14241 0.84  LDD2151 
Fos-related antigen 1 (FOSL1) LDTP02786 1.27  LDD2151 
Gamma-interferon-inducible protein 16 (IFI16) LDTP06602 0.23  LDD2151 
General transcription factor II-I (GTF2I) LDTP05101 1.00  LDD2151 
NF-kappa-B inhibitor beta (NFKBIB) LDTP06438 0.59  LDD2151 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 0.29  LDD2151 
Nuclear factor 1 C-type (NFIC) LDTP02296 0.73  LDD2151 
TATA box-binding protein-like 1 (TBPL1) LDTP04989 0.68  LDD2151 
Transcriptional activator protein Pur-alpha (PURA) LDTP05248 0.66  LDD2151 
Zinc finger protein 134 (ZNF134) LDTP14707 1.40  LDD2151 
Zinc finger protein 212 (ZNF212) LDTP13188 1.21  LDD2151 
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⏷ Show the Full List of 13 Transcription factor
1 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Intercellular adhesion molecule 1 (ICAM1) LDTP02106 1.00  LDD2151 
------------------------------------------------------------------------------------
304 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein sigma (SFN) LDTP03618 0.22  LDD2151 
17S U2 SnRNP complex component HTATSF1 (HTATSF1) LDTP00849 1.78  LDD2151 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 0.64; 0.44  LDD2151 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 0.34  LDD2151 
Actin-like protein 6A (ACTL6A) LDTP01756 0.39  LDD2151 
Actin-related protein 2 (ACTR2) LDTP04903 0.28; 0.42  LDD2151 
Actin-related protein 2/3 complex subunit 2 (ARPC2) LDTP00551 0.33  LDD2151 
Actin-related protein 2/3 complex subunit 3 (ARPC3) LDTP00552 0.37; 0.17  LDD2151 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 0.05  LDD2151 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 0.20  LDD2151 
Alpha-actinin-4 (ACTN4) LDTP00843 0.66  LDD2151 
Alpha-soluble NSF attachment protein (NAPA) LDTP04647 0.92; 0.19; 0.39  LDD2151 
Alpha-taxilin (TXLNA) LDTP03886 0.36  LDD2151 
Anillin (ANLN) LDTP12443 2.19; 0.97  LDD2151 
Astrocytic phosphoprotein PEA-15 (PEA15) LDTP06323 0.60  LDD2151 
Ataxin-2 (ATXN2) LDTP10947 1.51  LDD2151 
Bardet-Biedl syndrome 12 protein (BBS12) LDTP07861 2.25  LDD2151 
Barrier-to-autointegration factor (BANF1) LDTP01250 0.86  LDD2151 
Bcl-2-associated transcription factor 1 (BCLAF1) LDTP12826 1.04; 0.38  LDD2151 
BolA-like protein 2 (BOLA2; BOLA2B) LDTP11870 1.28  LDD2151 
BRCA2 and CDKN1A-interacting protein (BCCIP) LDTP13030 7.00  LDD2151 
BRO1 domain-containing protein BROX (BROX) LDTP07234 0.62  LDD2151 
Caldesmon (CALD1) LDTP05462 1.10  LDD2151 
Calmegin (CLGN) LDTP00493 1.19  LDD2151 
Calpastatin (CAST) LDTP03079 3.61  LDD2151 
cAMP-dependent protein kinase type I-beta regulatory subunit (PRKAR1B) LDTP03589 0.73  LDD2151 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 0.83  LDD2151 
Caprin-1 (CAPRIN1) LDTP06121 0.84  LDD2151 
Caspase recruitment domain-containing protein 11 (CARD11) LDTP11391 0.26  LDD2151 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 0.45  LDD2151 
Centromere protein F (CENPF) LDTP04258 0.99  LDD2151 
Centromere/kinetochore protein zw10 homolog (ZW10) LDTP00720 0.93; 0.33  LDD2151 
Centrosomal protein of 170 kDa (CEP170) LDTP07071 2.23  LDD2151 
CGG triplet repeat-binding protein 1 (CGGBP1) LDTP13217 1.06  LDD2151 
Charged multivesicular body protein 1b (CHMP1B) LDTP07984 0.63  LDD2151 
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6) LDTP06584 0.12  LDD2151 
Cleavage stimulation factor subunit 1 (CSTF1) LDTP14812 0.28  LDD2151 
Clustered mitochondria protein homolog (CLUH) LDTP14486 0.84; 2.01  LDD2151 
Coactosin-like protein (COTL1) LDTP06024 0.21  LDD2151 
Coatomer subunit alpha (COPA) LDTP04571 0.15  LDD2151 
Coatomer subunit beta (COPB1) LDTP04570 4.53; 0.39; 0.21 ...  LDD2151 
Coatomer subunit delta (ARCN1) LDTP04181 0.67; 0.18  LDD2151 
Coatomer subunit gamma-1 (COPG1) LDTP14216 0.73; 0.65  LDD2151 
Cofilin-1 (CFL1) LDTP03244 2.83; 1.55; 0.84 ...  LDD2151 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 0.91  LDD2151 
Condensin complex subunit 1 (NCAPD2) LDTP06281 0.84  LDD2151 
COP9 signalosome complex subunit 1 (GPS1) LDTP05746 0.29  LDD2151 
Core histone macro-H2A.1 (MACROH2A1) LDTP01195 0.52  LDD2151 
Cornulin (CRNN) LDTP13115 0.89  LDD2151 
Coronin-1B (CORO1B) LDTP11101 0.38; 0.48; 0.75  LDD2151 
Coronin-1C (CORO1C) LDTP13580 0.60; 0.52; 0.41  LDD2151 
Crk-like protein (CRKL) LDTP04092 1.24  LDD2151 
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) LDTP13269 2.14  LDD2151 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 0.32; 0.85; 0.22 ...  LDD2151 
Cytoplasmic FMR1-interacting protein 2 (CYFIP2) LDTP10289 3.32  LDD2151 
Cytoskeleton-associated protein 5 (CKAP5) LDTP06021 1.36  LDD2151 
DAZ-associated protein 1 (DAZAP1) LDTP10271 0.79; 0.28  LDD2151 
Dedicator of cytokinesis protein 7 (DOCK7) LDTP10613 1.81; 0.45; 0.44  LDD2151 
Destrin (DSTN) LDTP04887 0.45; 1.03; 1.58  LDD2151 
DNA damage-binding protein 1 (DDB1) LDTP06543 0.10; 0.42  LDD2151 
DNA mismatch repair protein Msh2 (MSH2) LDTP04028 3.16  LDD2151 
DNA mismatch repair protein Msh6 (MSH6) LDTP04518 0.81  LDD2151 
DnaJ homolog subfamily A member 1 (DNAJA1) LDTP03606 1.13  LDD2151 
DnaJ homolog subfamily C member 13 (DNAJC13) LDTP01149 0.48  LDD2151 
Drebrin (DBN1) LDTP06588 2.52; 2.74  LDD2151 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 0.51  LDD2151 
Dysbindin (DTNBP1) LDTP10279 1.47  LDD2151 
Early endosome antigen 1 (EEA1) LDTP06310 0.57  LDD2151 
ELAV-like protein 1 (ELAVL1) LDTP06450 0.65  LDD2151 
Elongation factor 1-gamma (EEF1G) LDTP03367 0.61; 0.06  LDD2151 
Endoplasmin (HSP90B1) LDTP02734 0.24  LDD2151 
Engulfment and cell motility protein 2 (ELMO2) LDTP10469 1.40  LDD2151 
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8L2) LDTP11998 0.89  LDD2151 
Epidermal growth factor receptor substrate 15 (EPS15) LDTP03982 0.45  LDD2151 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 0.08  LDD2151 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 1.44; 0.17; 0.66 ...  LDD2151 
Eukaryotic translation initiation factor 2A (EIF2A) LDTP11436 0.71  LDD2151 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 0.65; 0.26  LDD2151 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 0.36  LDD2151 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 0.27  LDD2151 
Eukaryotic translation initiation factor 3 subunit M (EIF3M) LDTP07947 0.56  LDD2151 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 1.19  LDD2151 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 0.62; 0.90  LDD2151 
Eukaryotic translation initiation factor 6 (EIF6) LDTP04743 0.30  LDD2151 
F-actin-capping protein subunit alpha-1 (CAPZA1) LDTP04544 0.95  LDD2151 
F-actin-capping protein subunit beta (CAPZB) LDTP04127 1.56  LDD2151 
Galectin-1 (LGALS1) LDTP02341 1.39; 0.41; 0.37  LDD2151 
Gem-associated protein 5 (GEMIN5) LDTP09504 1.81; 0.57  LDD2151 
General vesicular transport factor p115 (USO1) LDTP01048 0.93; 0.65  LDD2151 
Guanine nucleotide-binding protein subunit beta-4 (GNB4) LDTP12141 0.36  LDD2151 
H/ACA ribonucleoprotein complex subunit 2 (NHP2) LDTP12754 1.09; 0.10  LDD2151 
H/ACA ribonucleoprotein complex subunit 3 (NOP10) LDTP12350 1.35  LDD2151 
HEAT repeat-containing protein 1 (HEATR1) LDTP11948 1.00  LDD2151 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.28; 0.35; 0.70 ...  LDD2151 
Heat shock protein 105 kDa (HSPH1) LDTP09811 0.99  LDD2151 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 0.37  LDD2151 
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) LDTP00490 1.11  LDD2151 
Hepatoma-derived growth factor (HDGF) LDTP04483 2.23; 0.96  LDD2151 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 0.34  LDD2151 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 0.22  LDD2151 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 0.42  LDD2151 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 0.67  LDD2151 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 0.27  LDD2151 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 0.40  LDD2151 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 0.46  LDD2151 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 0.16; 0.19  LDD2151 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 0.29; 1.24; 1.06 ...  LDD2151 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 1.10; 0.34; 1.81  LDD2151 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 0.40  LDD2151 
Histone-binding protein RBBP4 (RBBP4) LDTP05590 0.94  LDD2151 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 0.96  LDD2151 
Host cell factor 1 (HCFC1) LDTP04434 0.27  LDD2151 
Hsc70-interacting protein (ST13) LDTP04367 0.14  LDD2151 
Inner centromere protein (INCENP) LDTP12432 1.21  LDD2151 
Integrin alpha-2 (ITGA2) LDTP02893 0.27  LDD2151 
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) LDTP00463 0.68  LDD2151 
Interleukin enhancer-binding factor 3 (ILF3) LDTP05689 0.38  LDD2151 
La-related protein 4B (LARP4B) LDTP09820 1.48  LDD2151 
Large ribosomal subunit protein bL20m (MRPL20) LDTP15914 0.54  LDD2151 
Large ribosomal subunit protein eL15 (RPL15) LDTP04919 0.66  LDD2151 
Large ribosomal subunit protein eL18 (RPL18) LDTP05509 0.41; 1.01  LDD2151 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 0.13; 0.76  LDD2151 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 3.03  LDD2151 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 0.73  LDD2151 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 0.72; 0.96  LDD2151 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 0.24  LDD2151 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 1.04  LDD2151 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 0.83  LDD2151 
Large ribosomal subunit protein eL36 (RPL36) LDTP14012 0.53  LDD2151 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 0.67  LDD2151 
Large ribosomal subunit protein eL8 (RPL7A) LDTP04990 1.56  LDD2151 
Large ribosomal subunit protein mL50 (MRPL50) LDTP15429 0.89  LDD2151 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 1.12  LDD2151 
Large ribosomal subunit protein uL11 (RPL12) LDTP03517 0.32; 0.69  LDD2151 
Large ribosomal subunit protein uL11m (MRPL11) LDTP13971 1.02  LDD2151 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 0.21  LDD2151 
Large ribosomal subunit protein uL22 (RPL17) LDTP02961 0.22  LDD2151 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 0.62; 0.11; 0.95 ...  LDD2151 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.27; 0.85  LDD2151 
Large ribosomal subunit protein uL5 (RPL11) LDTP05026 0.12; 0.29  LDD2151 
Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) LDTP03658 0.18; 1.57  LDD2151 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 0.27  LDD2151 
Leucine-rich repeat-containing protein 40 (LRRC40) LDTP19976 0.86  LDD2151 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 0.65; 0.64  LDD2151 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 1.55  LDD2151 
Matrin-3 (MATR3) LDTP04027 0.48; 0.50; 1.01  LDD2151 
Methylosome protein WDR77 (WDR77) LDTP11066 0.69  LDD2151 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 1.60  LDD2151 
Microtubule-associated protein 4 (MAP4) LDTP03404 7.05; 1.46; 2.11  LDD2151 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.31  LDD2151 
MKI67 FHA domain-interacting nucleolar phosphoprotein (NIFK) LDTP11457 1.22  LDD2151 
MOB-like protein phocein (MOB4) LDTP13964 1.16  LDD2151 
mRNA turnover protein 4 homolog (MRTO4) LDTP16220 2.25  LDD2151 
Myosin light polypeptide 6 (MYL6) LDTP04875 0.45  LDD2151 
Nck-associated protein 1 (NCKAP1) LDTP13839 0.22  LDD2151 
NHP2-like protein 1 (SNU13) LDTP04708 0.92  LDD2151 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 1.11  LDD2151 
Nuclear mitotic apparatus protein 1 (NUMA1) LDTP06244 0.58; 1.24; 1.68 ...  LDD2151 
Nucleolar protein 16 (NOP16) LDTP16278 0.29  LDD2151 
Nucleolar protein 56 (NOP56) LDTP00313 0.92  LDD2151 
Nucleolin (NCL) LDTP02990 0.66  LDD2151 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 1.91  LDD2151 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 0.59  LDD2151 
Ovarian cancer-related protein 1 (OCR1) LDTP20391 0.80  LDD2151 
Oxysterol-binding protein 1 (OSBP) LDTP03151 0.28  LDD2151 
PCNA-associated factor (PCLAF) LDTP06269 2.40  LDD2151 
PDZ and LIM domain protein 7 (PDLIM7) LDTP12461 0.71  LDD2151 
Peroxiredoxin-like 2A (PRXL2A) LDTP11140 1.25  LDD2151 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 3.65  LDD2151 
Phytanoyl-CoA hydroxylase-interacting protein (PHYHIP) LDTP15660 5.01  LDD2151 
Plastin-2 (LCP1) LDTP02691 1.41  LDD2151 
Plastin-3 (PLS3) LDTP02692 0.59  LDD2151 
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 0.39  LDD2151 
Plectin (PLEC) LDTP06330 0.33; 1.64  LDD2151 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 0.52  LDD2151 
Pre-mRNA-processing factor 6 (PRPF6) LDTP01456 1.48; 0.69  LDD2151 
Pre-mRNA-processing-splicing factor 8 (PRPF8) LDTP07526 0.99  LDD2151 
Prefoldin subunit 2 (PFDN2) LDTP13309 0.12  LDD2151 
Prefoldin subunit 5 (PFDN5) LDTP10873 0.89  LDD2151 
Prelamin-A/C (LMNA) LDTP01932 0.27  LDD2151 
Profilin-1 (PFN1) LDTP02218 0.10  LDD2151 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 1.63; 0.06  LDD2151 
Proliferating cell nuclear antigen (PCNA) LDTP02596 0.22  LDD2151 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 1.68; 0.64  LDD2151 
Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) LDTP08707 0.72  LDD2151 
Proteasomal ubiquitin receptor ADRM1 (ADRM1) LDTP06514 1.61  LDD2151 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 0.73  LDD2151 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 0.35  LDD2151 
Proteasome assembly chaperone 2 (PSMG2) LDTP10035 0.86  LDD2151 
Protein ECT2 (ECT2) LDTP12067 1.08  LDD2151 
Protein FAM98B (FAM98B) LDTP06879 0.61; 0.39  LDD2151 
Protein flightless-1 homolog (FLII) LDTP05734 0.75  LDD2151 
Protein NEDD1 (NEDD1) LDTP09266 2.26  LDD2151 
Protein Niban 1 (NIBAN1) LDTP11559 0.56  LDD2151 
Protein Niban 2 (NIBAN2) LDTP10847 3.23; 0.06  LDD2151 
Protein SGT1 homolog (SUGT1) LDTP13935 0.68  LDD2151 
Protein shisa-like-2A (SHISAL2A) LDTP17425 0.97  LDD2151 
Protein THEM6 (THEM6) LDTP19831 0.77  LDD2151 
Protein unc-45 homolog A (UNC45A) LDTP11890 0.22  LDD2151 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 1.02  LDD2151 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 1.11  LDD2151 
Raftlin (RFTN1) LDTP06193 1.44  LDD2151 
Ral GTPase-activating protein subunit beta (RALGAPB) LDTP15308 1.36  LDD2151 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 0.32  LDD2151 
Remodeling and spacing factor 1 (RSF1) LDTP10831 0.99  LDD2151 
Replication protein A 32 kDa subunit (RPA2) LDTP02816 0.91  LDD2151 
Replication termination factor 2 (RTF2) LDTP11434 0.99; 0.76  LDD2151 
Ribonuclease inhibitor (RNH1) LDTP02656 0.19  LDD2151 
Ribosomal L1 domain-containing protein 1 (RSL1D1) LDTP01379 0.20; 1.08  LDD2151 
Ribosomal RNA processing protein 1 homolog A (RRP1) LDTP04729 1.01  LDD2151 
Ribosome biogenesis protein BRX1 homolog (BRIX1) LDTP15609 4.12; 0.25  LDD2151 
Ribosome-binding protein 1 (RRBP1) LDTP13044 1.49; 1.13  LDD2151 
RNA polymerase-associated protein CTR9 homolog (CTR9) LDTP07563 0.52  LDD2151 
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1) LDTP03495 0.47  LDD2151 
RNA-binding protein FXR1 (FXR1) LDTP04395 1.03  LDD2151 
RNA-binding protein Raly (RALY) LDTP13467 0.11  LDD2151 
RNA-binding protein RO60 (RO60) LDTP02480 0.08; 0.54  LDD2151 
Scaffold attachment factor B1 (SAFB) LDTP06385 0.90; 2.59  LDD2151 
Scaffold attachment factor B2 (SAFB2) LDTP06054 2.04  LDD2151 
Sequestosome-1 (SQSTM1) LDTP05898 1.59  LDD2151 
Serine-threonine kinase receptor-associated protein (STRAP) LDTP13991 0.58  LDD2151 
Serine/arginine repetitive matrix protein 2 (SRRM2) LDTP13746 1.60; 2.11  LDD2151 
Serine/arginine-rich splicing factor 1 (SRSF1) LDTP05539 0.40  LDD2151 
Serine/arginine-rich splicing factor 11 (SRSF11) LDTP05458 1.77  LDD2151 
Serpin H1 (SERPINH1) LDTP04363 0.74  LDD2151 
SERPINE1 mRNA-binding protein 1 (SERBP1) LDTP09081 1.26  LDD2151 
Serrate RNA effector molecule homolog (SRRT) LDTP11398 0.99  LDD2151 
SH3 domain-containing kinase-binding protein 1 (SH3KBP1) LDTP10117 0.72  LDD2151 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 0.83  LDD2151 
Small nuclear ribonucleoprotein Sm D2 (SNRPD2) LDTP04982 1.05; 0.84  LDD2151 
Small nuclear ribonucleoprotein Sm D3 (SNRPD3) LDTP04983 0.28  LDD2151 
Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB) LDTP02741 0.30  LDD2151 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 0.69; 0.81; 0.48  LDD2151 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 0.72; 0.61; 0.09  LDD2151 
Small ribosomal subunit protein eS21 (RPS21) LDTP05055 0.74  LDD2151 
Small ribosomal subunit protein eS25 (RPS25) LDTP05013 0.78  LDD2151 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 0.64  LDD2151 
Small ribosomal subunit protein eS28 (RPS28) LDTP05015 0.75  LDD2151 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 0.58  LDD2151 
Small ribosomal subunit protein eS6 (RPS6) LDTP05002 0.87  LDD2151 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 1.43  LDD2151 
Small ribosomal subunit protein uS10 (RPS20) LDTP04880 1.06; 0.37  LDD2151 
Small ribosomal subunit protein uS11 (RPS14) LDTP04970 0.08  LDD2151 
Small ribosomal subunit protein uS14 (RPS29) LDTP04973 0.32  LDD2151 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 0.22; 2.55; 0.17  LDD2151 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 0.55  LDD2151 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 1.19  LDD2151 
Small ribosomal subunit protein uS8 (RPS15A) LDTP04965 0.53; 0.25  LDD2151 
Small ribosomal subunit protein uS9 (RPS16) LDTP04966 0.20; 0.21  LDD2151 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 0.55  LDD2151 
Smoothelin (SMTN) LDTP04590 2.87  LDD2151 
Sorcin (SRI) LDTP03554 0.64  LDD2151 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 0.68; 0.20  LDD2151 
Splicing factor 1 (SF1) LDTP06429 0.51  LDD2151 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 0.29; 0.92; 0.10 ...  LDD2151 
Splicing factor 45 (RBM17) LDTP10409 2.04  LDD2151 
Splicing factor U2AF 35 kDa subunit (U2AF1) LDTP05272 0.98  LDD2151 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 0.85  LDD2151 
Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) LDTP06280 0.36; 0.19  LDD2151 
SRA stem-loop-interacting RNA-binding protein, mitochondrial (SLIRP) LDTP11645 0.69  LDD2151 
Src substrate cortactin (CTTN) LDTP06094 1.24  LDD2151 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 0.29; 2.02  LDD2151 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 0.16; 0.08; 1.08 ...  LDD2151 
Striatin-4 (STRN4) LDTP12519 0.96  LDD2151 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 0.14; 0.56  LDD2151 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 0.50  LDD2151 
Structural maintenance of chromosomes protein 3 (SMC3) LDTP13760 0.25  LDD2151 
Synembryn-A (RIC8A) LDTP12381 0.97  LDD2151 
T-complex protein 1 subunit beta (CCT2) LDTP05113 0.33  LDD2151 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 0.13; 0.60; 0.76 ...  LDD2151 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.21; 0.29  LDD2151 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 0.46; 0.61; 0.10 ...  LDD2151 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.16; 0.53; 0.50  LDD2151 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.74; 0.48  LDD2151 
TAR DNA-binding protein 43 (TARDBP) LDTP05767 1.44  LDD2151 
Tetratricopeptide repeat protein 39A (TTC39A) LDTP17208 0.55  LDD2151 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 1.02  LDD2151 
Transcription elongation factor SPT5 (SUPT5H) LDTP00236 0.72  LDD2151 
Transducin beta-like protein 2 (TBL2) LDTP16285 1.72  LDD2151 
Transgelin-2 (TAGLN2) LDTP03846 0.07  LDD2151 
Translationally-controlled tumor protein (TPT1) LDTP02683 0.76  LDD2151 
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WDR6) LDTP12296 0.67  LDD2151 
Tubulin beta-6 chain (TUBB6) LDTP11233 1.06  LDD2151 
Tubulin-folding cofactor B (TBCB) LDTP10860 0.36; 0.29  LDD2151 
Tumor protein D54 (TPD52L2) LDTP00759 0.63  LDD2151 
Twinfilin-2 (TWF2) LDTP07404 0.68  LDD2151 
U3 small nucleolar RNA-associated protein 6 homolog (UTP6) LDTP12830 1.13  LDD2151 
U6 snRNA-associated Sm-like protein LSm4 (LSM4) LDTP14081 0.78  LDD2151 
Ubiquitin-like protein 5 (UBL5) LDTP11545 0.54  LDD2151 
Ubiquitin-ribosomal protein eL40 fusion protein (UBA52) LDTP05034 2.34  LDD2151 
Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) LDTP05033 0.29  LDD2151 
UBX domain-containing protein 4 (UBXN4) LDTP09806 2.59  LDD2151 
UPF0449 protein C19orf25 (C19orf25) LDTP13214 0.97  LDD2151 
Vigilin (HDLBP) LDTP05239 0.59; 0.64; 1.16  LDD2151 
Vimentin (VIM) LDTP02297 1.00  LDD2151 
Vinculin (VCL) LDTP02946 0.38; 0.63; 0.32 ...  LDD2151 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.47  LDD2151 
WD repeat-containing protein 1 (WDR1) LDTP01118 1.49; 0.38  LDD2151 
WD repeat-containing protein 43 (WDR43) LDTP06305 0.83  LDD2151 
WD40 repeat-containing protein SMU1 (SMU1) LDTP06726 0.88; 0.33  LDD2151 
WW domain-containing adapter protein with coiled-coil (WAC) LDTP11191 0.61  LDD2151 
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) LDTP08018 1.04  LDD2151 
Zinc finger protein 185 (ZNF185) LDTP00580 1.82  LDD2151 
Zinc finger RNA-binding protein (ZFR) LDTP15762 0.29; 0.74  LDD2151 
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Full Information of The Labelling Profiles of This Competitor

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 5 mM
Quantitative Method Isotope tag
Experimemt Name ISO-TOP ABPP
Competitor Name Nucleophilic fragment 8b
Competitor Concentration 0.5 mM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cell lysate (MDA-MB-231)
Interaction Atlas ID  LDD2151  Download The Altas

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761