Details of the Target

General Information of Target

Target ID LDTP05716
Target Name BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (BNIP2)
Gene Name BNIP2
Gene ID 663
Synonyms
NIP2; BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MEGVELKEEWQDEDFPIPLPEDDSIEADILAITGPEDQPGSLEVNGNKVRKKLMAPDISL
TLDPSDGSVLSDDLDESGEIDLDGLDTPSENSNEFEWEDDLPKPKTTEVIRKGSITEYTA
AEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYGDGLNAIVVFAVCFMPESSQ
PNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRRLRKN
LKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQVD
QELNGKQDEPKNEQ
Target Bioclass
Enzyme
Subcellular location
Cytoplasm
Function Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.
Uniprot ID
Q12982
Ensemble ID
ENST00000415213.7
HGNC ID
HGNC:1083

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CHL1 SNV: p.M144T DBIA    Probe Info 
KYSE30 SNV: p.G78A .
TKKK SNV: p.E36Q .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]
DBIA
 Probe Info  		C357(1.73)  LDD3332  [2]
BTD
 Probe Info  		C229(1.07)  LDD2094  [3]
IA-alkyne
 Probe Info  		C295(0.00); C229(0.00)  LDD0036  [4]
Lodoacetamide azide
 Probe Info  		C229(0.00); C295(0.00)  LDD0037  [4]
NAIA_4
 Probe Info  		N.A.  LDD2226  [5]
TFBX
 Probe Info  		N.A.  LDD0027  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C229(0.45)  LDD2095  [3]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C229(0.98)  LDD2117  [3]
 LDCM0563  Abegg_cp(+)-11 HeLa C229(2.28)  LDD0314  [6]
 LDCM0561  Abegg_cp(-)-10 HeLa C229(2.40)  LDD0312  [6]
 LDCM0214  AC1 HEK-293T C229(0.89)  LDD1507  [7]
 LDCM0215  AC10 HEK-293T C229(0.92)  LDD1508  [7]
 LDCM0226  AC11 HEK-293T C229(1.03)  LDD1509  [7]
 LDCM0237  AC12 HEK-293T C229(1.08)  LDD1510  [7]
 LDCM0259  AC14 HEK-293T C229(1.06)  LDD1512  [7]
 LDCM0270  AC15 HEK-293T C229(1.05)  LDD1513  [7]
 LDCM0276  AC17 HEK-293T C229(1.13)  LDD1515  [7]
 LDCM0277  AC18 HEK-293T C229(0.96)  LDD1516  [7]
 LDCM0278  AC19 HEK-293T C229(1.09)  LDD1517  [7]
 LDCM0279  AC2 HEK-293T C229(0.98)  LDD1518  [7]
 LDCM0280  AC20 HEK-293T C229(0.88)  LDD1519  [7]
 LDCM0281  AC21 HEK-293T C229(0.99)  LDD1520  [7]
 LDCM0282  AC22 HEK-293T C229(1.03)  LDD1521  [7]
 LDCM0283  AC23 HEK-293T C229(1.06)  LDD1522  [7]
 LDCM0284  AC24 HEK-293T C229(1.05)  LDD1523  [7]
 LDCM0285  AC25 HEK-293T C229(0.89)  LDD1524  [7]
 LDCM0286  AC26 HEK-293T C229(1.04)  LDD1525  [7]
 LDCM0287  AC27 HEK-293T C229(1.01)  LDD1526  [7]
 LDCM0288  AC28 HEK-293T C229(1.13)  LDD1527  [7]
 LDCM0289  AC29 HEK-293T C229(0.87)  LDD1528  [7]
 LDCM0290  AC3 HEK-293T C229(0.98)  LDD1529  [7]
 LDCM0291  AC30 HEK-293T C229(0.99)  LDD1530  [7]
 LDCM0292  AC31 HEK-293T C229(0.98)  LDD1531  [7]
 LDCM0293  AC32 HEK-293T C229(1.08)  LDD1532  [7]
 LDCM0294  AC33 HEK-293T C229(0.98)  LDD1533  [7]
 LDCM0295  AC34 HEK-293T C229(0.94)  LDD1534  [7]
 LDCM0296  AC35 HEK-293T C229(1.03)  LDD1535  [7]
 LDCM0297  AC36 HEK-293T C229(1.29)  LDD1536  [7]
 LDCM0298  AC37 HEK-293T C229(1.06)  LDD1537  [7]
 LDCM0299  AC38 HEK-293T C229(1.09)  LDD1538  [7]
 LDCM0300  AC39 HEK-293T C229(1.09)  LDD1539  [7]
 LDCM0301  AC4 HEK-293T C229(1.14)  LDD1540  [7]
 LDCM0302  AC40 HEK-293T C229(1.05)  LDD1541  [7]
 LDCM0303  AC41 HEK-293T C229(0.87)  LDD1542  [7]
 LDCM0304  AC42 HEK-293T C229(0.97)  LDD1543  [7]
 LDCM0305  AC43 HEK-293T C229(1.03)  LDD1544  [7]
 LDCM0306  AC44 HEK-293T C229(1.00)  LDD1545  [7]
 LDCM0307  AC45 HEK-293T C229(0.88)  LDD1546  [7]
 LDCM0308  AC46 HEK-293T C229(0.98)  LDD1547  [7]
 LDCM0309  AC47 HEK-293T C229(1.01)  LDD1548  [7]
 LDCM0310  AC48 HEK-293T C229(1.03)  LDD1549  [7]
 LDCM0311  AC49 HEK-293T C229(1.14)  LDD1550  [7]
 LDCM0312  AC5 HEK-293T C229(0.89)  LDD1551  [7]
 LDCM0313  AC50 HEK-293T C229(1.00)  LDD1552  [7]
 LDCM0314  AC51 HEK-293T C229(1.04)  LDD1553  [7]
 LDCM0315  AC52 HEK-293T C229(0.92)  LDD1554  [7]
 LDCM0316  AC53 HEK-293T C229(0.95)  LDD1555  [7]
 LDCM0317  AC54 HEK-293T C229(1.14)  LDD1556  [7]
 LDCM0318  AC55 HEK-293T C229(1.07)  LDD1557  [7]
 LDCM0319  AC56 HEK-293T C229(1.05)  LDD1558  [7]
 LDCM0320  AC57 HEK-293T C229(1.01)  LDD1559  [7]
 LDCM0321  AC58 HEK-293T C229(0.98)  LDD1560  [7]
 LDCM0322  AC59 HEK-293T C229(1.02)  LDD1561  [7]
 LDCM0323  AC6 HEK-293T C229(0.91)  LDD1562  [7]
 LDCM0324  AC60 HEK-293T C229(1.11)  LDD1563  [7]
 LDCM0325  AC61 HEK-293T C229(1.00)  LDD1564  [7]
 LDCM0326  AC62 HEK-293T C229(0.96)  LDD1565  [7]
 LDCM0327  AC63 HEK-293T C229(1.03)  LDD1566  [7]
 LDCM0328  AC64 HEK-293T C229(0.97)  LDD1567  [7]
 LDCM0334  AC7 HEK-293T C229(0.98)  LDD1568  [7]
 LDCM0345  AC8 HEK-293T C229(1.03)  LDD1569  [7]
 LDCM0248  AKOS034007472 HEK-293T C229(1.03)  LDD1511  [7]
 LDCM0356  AKOS034007680 HEK-293T C229(0.96)  LDD1570  [7]
 LDCM0275  AKOS034007705 HEK-293T C229(1.07)  LDD1514  [7]
 LDCM0367  CL1 HEK-293T C229(0.93)  LDD1571  [7]
 LDCM0368  CL10 HEK-293T C229(0.96)  LDD1572  [7]
 LDCM0369  CL100 HEK-293T C229(0.98)  LDD1573  [7]
 LDCM0370  CL101 HEK-293T C229(1.10)  LDD1574  [7]
 LDCM0371  CL102 HEK-293T C229(1.06)  LDD1575  [7]
 LDCM0372  CL103 HEK-293T C229(1.06)  LDD1576  [7]
 LDCM0373  CL104 HEK-293T C229(1.03)  LDD1577  [7]
 LDCM0374  CL105 HEK-293T C229(1.01)  LDD1578  [7]
 LDCM0375  CL106 HEK-293T C229(1.15)  LDD1579  [7]
 LDCM0376  CL107 HEK-293T C229(1.04)  LDD1580  [7]
 LDCM0377  CL108 HEK-293T C229(1.07)  LDD1581  [7]
 LDCM0378  CL109 HEK-293T C229(1.01)  LDD1582  [7]
 LDCM0379  CL11 HEK-293T C229(1.22)  LDD1583  [7]
 LDCM0380  CL110 HEK-293T C229(1.02)  LDD1584  [7]
 LDCM0381  CL111 HEK-293T C229(0.95)  LDD1585  [7]
 LDCM0382  CL112 HEK-293T C229(0.95)  LDD1586  [7]
 LDCM0383  CL113 HEK-293T C229(1.06)  LDD1587  [7]
 LDCM0384  CL114 HEK-293T C229(0.96)  LDD1588  [7]
 LDCM0385  CL115 HEK-293T C229(1.06)  LDD1589  [7]
 LDCM0386  CL116 HEK-293T C229(0.96)  LDD1590  [7]
 LDCM0387  CL117 HEK-293T C229(1.02)  LDD1591  [7]
 LDCM0388  CL118 HEK-293T C229(1.10)  LDD1592  [7]
 LDCM0389  CL119 HEK-293T C229(1.11)  LDD1593  [7]
 LDCM0390  CL12 HEK-293T C229(1.16)  LDD1594  [7]
 LDCM0391  CL120 HEK-293T C229(1.04)  LDD1595  [7]
 LDCM0392  CL121 HEK-293T C229(1.07)  LDD1596  [7]
 LDCM0393  CL122 HEK-293T C229(1.05)  LDD1597  [7]
 LDCM0394  CL123 HEK-293T C229(1.05)  LDD1598  [7]
 LDCM0395  CL124 HEK-293T C229(1.13)  LDD1599  [7]
 LDCM0396  CL125 HEK-293T C229(1.00)  LDD1600  [7]
 LDCM0397  CL126 HEK-293T C229(0.93)  LDD1601  [7]
 LDCM0398  CL127 HEK-293T C229(1.03)  LDD1602  [7]
 LDCM0399  CL128 HEK-293T C229(0.91)  LDD1603  [7]
 LDCM0400  CL13 HEK-293T C229(1.00)  LDD1604  [7]
 LDCM0401  CL14 HEK-293T C229(1.05)  LDD1605  [7]
 LDCM0402  CL15 HEK-293T C229(1.06)  LDD1606  [7]
 LDCM0403  CL16 HEK-293T C229(1.14)  LDD1607  [7]
 LDCM0404  CL17 HEK-293T C229(0.94)  LDD1608  [7]
 LDCM0405  CL18 HEK-293T C229(1.06)  LDD1609  [7]
 LDCM0406  CL19 HEK-293T C229(1.19)  LDD1610  [7]
 LDCM0407  CL2 HEK-293T C229(1.00)  LDD1611  [7]
 LDCM0408  CL20 HEK-293T C229(1.23)  LDD1612  [7]
 LDCM0409  CL21 HEK-293T C229(1.21)  LDD1613  [7]
 LDCM0410  CL22 HEK-293T C229(1.19)  LDD1614  [7]
 LDCM0411  CL23 HEK-293T C229(1.40)  LDD1615  [7]
 LDCM0412  CL24 HEK-293T C229(1.15)  LDD1616  [7]
 LDCM0413  CL25 HEK-293T C229(0.93)  LDD1617  [7]
 LDCM0414  CL26 HEK-293T C229(1.11)  LDD1618  [7]
 LDCM0415  CL27 HEK-293T C229(1.03)  LDD1619  [7]
 LDCM0416  CL28 HEK-293T C229(1.05)  LDD1620  [7]
 LDCM0417  CL29 HEK-293T C229(1.02)  LDD1621  [7]
 LDCM0418  CL3 HEK-293T C229(0.98)  LDD1622  [7]
 LDCM0419  CL30 HEK-293T C229(1.05)  LDD1623  [7]
 LDCM0420  CL31 HEK-293T C229(1.12)  LDD1624  [7]
 LDCM0421  CL32 HEK-293T C229(1.09)  LDD1625  [7]
 LDCM0422  CL33 HEK-293T C229(1.16)  LDD1626  [7]
 LDCM0423  CL34 HEK-293T C229(1.20)  LDD1627  [7]
 LDCM0424  CL35 HEK-293T C229(1.23)  LDD1628  [7]
 LDCM0425  CL36 HEK-293T C229(1.20)  LDD1629  [7]
 LDCM0426  CL37 HEK-293T C229(0.94)  LDD1630  [7]
 LDCM0428  CL39 HEK-293T C229(0.99)  LDD1632  [7]
 LDCM0429  CL4 HEK-293T C229(0.98)  LDD1633  [7]
 LDCM0430  CL40 HEK-293T C229(1.08)  LDD1634  [7]
 LDCM0431  CL41 HEK-293T C229(0.90)  LDD1635  [7]
 LDCM0432  CL42 HEK-293T C229(1.11)  LDD1636  [7]
 LDCM0433  CL43 HEK-293T C229(0.99)  LDD1637  [7]
 LDCM0434  CL44 HEK-293T C229(1.07)  LDD1638  [7]
 LDCM0435  CL45 HEK-293T C229(0.88)  LDD1639  [7]
 LDCM0436  CL46 HEK-293T C229(1.20)  LDD1640  [7]
 LDCM0437  CL47 HEK-293T C229(1.17)  LDD1641  [7]
 LDCM0438  CL48 HEK-293T C229(1.17)  LDD1642  [7]
 LDCM0439  CL49 HEK-293T C229(0.93)  LDD1643  [7]
 LDCM0440  CL5 HEK-293T C229(0.94)  LDD1644  [7]
 LDCM0441  CL50 HEK-293T C229(1.05)  LDD1645  [7]
 LDCM0443  CL52 HEK-293T C229(1.00)  LDD1646  [7]
 LDCM0444  CL53 HEK-293T C229(1.18)  LDD1647  [7]
 LDCM0445  CL54 HEK-293T C229(1.07)  LDD1648  [7]
 LDCM0446  CL55 HEK-293T C229(1.15)  LDD1649  [7]
 LDCM0447  CL56 HEK-293T C229(1.04)  LDD1650  [7]
 LDCM0448  CL57 HEK-293T C229(0.95)  LDD1651  [7]
 LDCM0449  CL58 HEK-293T C229(1.36)  LDD1652  [7]
 LDCM0450  CL59 HEK-293T C229(1.18)  LDD1653  [7]
 LDCM0451  CL6 HEK-293T C229(0.95)  LDD1654  [7]
 LDCM0452  CL60 HEK-293T C229(1.14)  LDD1655  [7]
 LDCM0453  CL61 HEK-293T C229(1.01)  LDD1656  [7]
 LDCM0454  CL62 HEK-293T C229(1.11)  LDD1657  [7]
 LDCM0455  CL63 HEK-293T C229(1.12)  LDD1658  [7]
 LDCM0456  CL64 HEK-293T C229(1.03)  LDD1659  [7]
 LDCM0457  CL65 HEK-293T C229(1.04)  LDD1660  [7]
 LDCM0458  CL66 HEK-293T C229(1.03)  LDD1661  [7]
 LDCM0459  CL67 HEK-293T C229(1.10)  LDD1662  [7]
 LDCM0460  CL68 HEK-293T C229(1.05)  LDD1663  [7]
 LDCM0461  CL69 HEK-293T C229(0.96)  LDD1664  [7]
 LDCM0462  CL7 HEK-293T C229(1.05)  LDD1665  [7]
 LDCM0463  CL70 HEK-293T C229(1.17)  LDD1666  [7]
 LDCM0464  CL71 HEK-293T C229(1.41)  LDD1667  [7]
 LDCM0465  CL72 HEK-293T C229(1.12)  LDD1668  [7]
 LDCM0466  CL73 HEK-293T C229(1.06)  LDD1669  [7]
 LDCM0467  CL74 HEK-293T C229(1.09)  LDD1670  [7]
 LDCM0469  CL76 HEK-293T C229(1.02)  LDD1672  [7]
 LDCM0470  CL77 HEK-293T C229(0.92)  LDD1673  [7]
 LDCM0471  CL78 HEK-293T C229(0.95)  LDD1674  [7]
 LDCM0472  CL79 HEK-293T C229(1.12)  LDD1675  [7]
 LDCM0473  CL8 HEK-293T C229(1.15)  LDD1676  [7]
 LDCM0474  CL80 HEK-293T C229(1.14)  LDD1677  [7]
 LDCM0475  CL81 HEK-293T C229(0.97)  LDD1678  [7]
 LDCM0476  CL82 HEK-293T C229(1.07)  LDD1679  [7]
 LDCM0477  CL83 HEK-293T C229(1.16)  LDD1680  [7]
 LDCM0478  CL84 HEK-293T C229(1.11)  LDD1681  [7]
 LDCM0479  CL85 HEK-293T C229(0.98)  LDD1682  [7]
 LDCM0480  CL86 HEK-293T C229(0.96)  LDD1683  [7]
 LDCM0481  CL87 HEK-293T C229(1.06)  LDD1684  [7]
 LDCM0482  CL88 HEK-293T C229(1.03)  LDD1685  [7]
 LDCM0483  CL89 HEK-293T C229(0.91)  LDD1686  [7]
 LDCM0484  CL9 HEK-293T C229(1.01)  LDD1687  [7]
 LDCM0485  CL90 HEK-293T C229(0.94)  LDD1688  [7]
 LDCM0486  CL91 HEK-293T C229(1.10)  LDD1689  [7]
 LDCM0487  CL92 HEK-293T C229(0.82)  LDD1690  [7]
 LDCM0488  CL93 HEK-293T C229(0.94)  LDD1691  [7]
 LDCM0489  CL94 HEK-293T C229(1.05)  LDD1692  [7]
 LDCM0490  CL95 HEK-293T C229(0.98)  LDD1693  [7]
 LDCM0491  CL96 HEK-293T C229(1.03)  LDD1694  [7]
 LDCM0492  CL97 HEK-293T C229(0.98)  LDD1695  [7]
 LDCM0493  CL98 HEK-293T C229(0.97)  LDD1696  [7]
 LDCM0494  CL99 HEK-293T C229(0.97)  LDD1697  [7]
 LDCM0198  Dimethyl Fumarate(DMF) T cell C295(4.02)  LDD0526  [8]
 LDCM0495  E2913 HEK-293T C229(1.03)  LDD1698  [7]
 LDCM0625  F8 Ramos C229(2.30)  LDD2187  [9]
 LDCM0573  Fragment11 Ramos C229(20.00)  LDD2190  [9]
 LDCM0576  Fragment14 Ramos C229(1.09)  LDD2193  [9]
 LDCM0468  Fragment33 HEK-293T C229(1.02)  LDD1671  [7]
 LDCM0566  Fragment4 Ramos C229(0.81)  LDD2184  [9]
 LDCM0427  Fragment51 HEK-293T C229(1.01)  LDD1631  [7]
 LDCM0569  Fragment7 Ramos C229(0.57)  LDD2186  [9]
 LDCM0022  KB02 Ramos C229(0.73)  LDD2182  [9]
 LDCM0023  KB03 Ramos C229(0.92)  LDD2183  [9]
 LDCM0024  KB05 MKN45 C357(1.73)  LDD3332  [2]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C229(1.07)  LDD2094  [3]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C229(0.32)  LDD2096  [3]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C229(1.64)  LDD2099  [3]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C229(1.21)  LDD2107  [3]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C229(0.54)  LDD2109  [3]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C229(1.17)  LDD2111  [3]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C229(0.71)  LDD2116  [3]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C229(0.81)  LDD2118  [3]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C229(1.22)  LDD2119  [3]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C229(0.74)  LDD2122  [3]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C229(0.85)  LDD2123  [3]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C229(0.62)  LDD2124  [3]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C229(0.74)  LDD2125  [3]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C229(0.48)  LDD2126  [3]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C229(1.18)  LDD2127  [3]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C229(1.29)  LDD2129  [3]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C229(1.57)  LDD2135  [3]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C229(1.12)  LDD2137  [3]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C229(0.92)  LDD2140  [3]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C229(0.94)  LDD2146  [3]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C229(0.54)  LDD2149  [3]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C229(0.96)  LDD2151  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3) 1-acyl-sn-glycerol-3-phosphate acyltransferase family Q9NRZ7
Deubiquitinase DESI2 (DESI2) DeSI family Q9BSY9
Diacylglycerol O-acyltransferase 2-like protein 6 (DGAT2L6) Diacylglycerol acyltransferase family Q6ZPD8
NADH-cytochrome b5 reductase 3 (CYB5R3) Flavoprotein pyridine nucleotide cytochrome reductase family P00387
Probable glutathione peroxidase 8 (GPX8) Glutathione peroxidase family Q8TED1
(Lyso)-N-acylphosphatidylethanolamine lipase (ABHD4) Peptidase S33 family Q8TB40
Tyrosine-protein kinase FRK (FRK) Tyr protein kinase family P42685
Dehydrogenase/reductase SDR family member 1 (DHRS1) Short-chain dehydrogenases/reductases (SDR) family Q96LJ7
Unconventional myosin-Vb (MYO5B) Myosin family Q9ULV0
Transporter and channel
Click To Hide/Show 10 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Solute carrier family 7 member 14 (SLC7A14) Cationic amino acid transporter (CAT) (TC 2.A.3.3) family Q8TBB6
Erlin-1 (ERLIN1) Band 7/mec-2 family O75477
Etoposide-induced protein 2.4 homolog (EI24) EI24 family O14681
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) NIP3 family Q12983
Peroxisome assembly protein 12 (PEX12) Pex2/pex10/pex12 family O00623
Synaptotagmin-1 (SYT1) Synaptotagmin family P21579
Solute carrier family 35 member E3 (SLC35E3) TPT transporter family Q7Z769
Potassium channel subfamily K member 5 (KCNK5) Two pore domain potassium channel (TC 1.A.1.8) family O95279
Zinc transporter ZIP9 (SLC39A9) ZIP transporter (TC 2.A.5) family Q9NUM3
Thioredoxin-related transmembrane protein 2 (TMX2) . Q9Y320
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein goosecoid-2 (GSC2) Paired homeobox family O15499
Homeobox protein MOX-1 (MEOX1) . P50221
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable G-protein coupled receptor 152 (GPR152) G-protein coupled receptor 1 family Q8TDT2
Other
Click To Hide/Show 15 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Complexin-4 (CPLX4) Complexin/synaphin family Q7Z7G2
Protein FAM209A (FAM209A) FAM209 family Q5JX71
Protein FAM3C (FAM3C) FAM3 family Q92520
RAB6-interacting golgin (GORAB) GORAB family Q5T7V8
Kinesin light chain 1 (KLC1) Kinesin light chain family Q07866
Low-density lipoprotein receptor class A domain-containing protein 1 (LDLRAD1) LDLR family Q5T700
Vesicle transport protein SFT2B (SFT2D2) SFT2 family O95562
Synaptotagmin-2 (SYT2) Synaptotagmin family Q8N9I0
Protein YIF1A (YIF1A) YIF1 family O95070
Chondrolectin (CHODL) . Q9H9P2
Fetal and adult testis-expressed transcript protein (FATE1) . Q969F0
GRAM domain-containing protein 2A (GRAMD2A) . Q8IUY3
Lck-interacting transmembrane adapter 1 (LIME1) . Q9H400
Pleckstrin homology domain-containing family O member 1 (PLEKHO1) . Q53GL0
Protein BNIP5 (BNIP5) . P0C671

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
5 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
6 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
8 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
9 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578