Details of the Target

General Information of Target

Target ID LDTP03886
Target Name Alpha-taxilin (TXLNA)
Gene Name TXLNA
Gene ID 200081
Synonyms
TXLN; Alpha-taxilin
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKNQDKKNGAAKQSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPRKPEGAQA
RTAQSGALRDVSEELSRQLEDILSTYCVDNNQGGPGEDGAQGEPAEPEDAEKSRTYVARN
GEPEPTPVVNGEKEPSKGDPNTEEIRQSDEVGDRDHRRPQEKKKAKGLGKEITLLMQTLN
TLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSK
LESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQ
ENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKD
FLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTK
KIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEKLCRALQTERND
LNKRVQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPRVTEAPCYPGAPSTEASGQTGPQE
PTSARA
Target Bioclass
Other
Family
Taxilin family
Function May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
Uniprot ID
P40222
Ensemble ID
ENST00000373609.1
HGNC ID
HGNC:30685

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 31 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
CY-1
 Probe Info  		100.00  LDD0243  [2]
W1
 Probe Info  		10.04  LDD0235  [3]
YN-1
 Probe Info  		100.00  LDD0444  [4]
BTD
 Probe Info  		C373(2.45)  LDD1699  [5]
ONAyne
 Probe Info  		N.A.  LDD0273  [6]
OPA-S-S-alkyne
 Probe Info  		K240(1.67); K256(3.67)  LDD3494  [7]
Probe 1
 Probe Info  		Y390(12.04)  LDD3495  [8]
AHL-Pu-1
 Probe Info  		C87(2.48); C523(2.96)  LDD0169  [9]
Alkyne-RA190
 Probe Info  		4.76  LDD0300  [10]
HHS-475
 Probe Info  		Y390(0.81); Y524(0.88)  LDD0264  [11]
HHS-465
 Probe Info  		Y390(1.53)  LDD2237  [12]
DBIA
 Probe Info  		C523(0.99)  LDD0078  [13]
ATP probe
 Probe Info  		K325(0.00); K195(0.00); K412(0.00); K417(0.00)  LDD0199  [14]
IA-alkyne
 Probe Info  		C87(0.00); C373(0.00); C193(0.00)  LDD0032  [15]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [16]
IPM
 Probe Info  		N.A.  LDD0025  [17]
NAIA_4
 Probe Info  		C87(0.00); C523(0.00); 0.00  LDD2226  [18]
TFBX
 Probe Info  		C193(0.00); C523(0.00)  LDD0027  [17]
WYneN
 Probe Info  		N.A.  LDD0021  [19]
NHS
 Probe Info  		K195(0.00); K463(0.00)  LDD0010  [19]
PF-06672131
 Probe Info  		N.A.  LDD0017  [20]
PPMS
 Probe Info  		N.A.  LDD0008  [19]
STPyne
 Probe Info  		K330(0.00); K463(0.00)  LDD0009  [19]
VSF
 Probe Info  		C245(0.00); C523(0.00)  LDD0007  [19]
Phosphinate-6
 Probe Info  		C193(0.00); C523(0.00); C245(0.00)  LDD0018  [21]
1c-yne
 Probe Info  		K340(0.00); K170(0.00)  LDD0228  [22]
Acrolein
 Probe Info  		N.A.  LDD0217  [23]
Methacrolein
 Probe Info  		N.A.  LDD0218  [23]
AOyne
 Probe Info  		5.00  LDD0443  [24]
NAIA_5
 Probe Info  		C193(0.00); C245(0.00)  LDD2223  [18]
PAL-AfBPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe11
 Probe Info  		5.99  LDD0471  [25]
FFF probe13
 Probe Info  		20.00  LDD0475  [25]
FFF probe2
 Probe Info  		13.03  LDD0463  [25]
STS-2
 Probe Info  		N.A.  LDD0139  [26]
VE-P
 Probe Info  		N.A.  LDD0396  [27]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C373(0.48)  LDD2112  [5]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C373(1.00)  LDD2117  [5]
 LDCM0026  4SU-RNA+native RNA HEK-293T C87(2.48); C523(2.96)  LDD0169  [9]
 LDCM0214  AC1 HCT 116 C523(1.03)  LDD0531  [13]
 LDCM0215  AC10 HCT 116 C523(1.41)  LDD0532  [13]
 LDCM0216  AC100 HCT 116 C523(1.04)  LDD0533  [13]
 LDCM0217  AC101 HCT 116 C523(0.97)  LDD0534  [13]
 LDCM0218  AC102 HCT 116 C523(1.11)  LDD0535  [13]
 LDCM0219  AC103 HCT 116 C523(1.41)  LDD0536  [13]
 LDCM0220  AC104 HCT 116 C523(1.24)  LDD0537  [13]
 LDCM0221  AC105 HCT 116 C523(1.16)  LDD0538  [13]
 LDCM0222  AC106 HCT 116 C523(1.28)  LDD0539  [13]
 LDCM0223  AC107 HCT 116 C523(1.87)  LDD0540  [13]
 LDCM0224  AC108 HCT 116 C523(1.12)  LDD0541  [13]
 LDCM0225  AC109 HCT 116 C523(1.95)  LDD0542  [13]
 LDCM0226  AC11 HCT 116 C523(1.39)  LDD0543  [13]
 LDCM0227  AC110 HCT 116 C523(2.28)  LDD0544  [13]
 LDCM0228  AC111 HCT 116 C523(1.60)  LDD0545  [13]
 LDCM0229  AC112 HCT 116 C523(1.58)  LDD0546  [13]
 LDCM0230  AC113 HCT 116 C523(0.98)  LDD0547  [13]
 LDCM0231  AC114 HCT 116 C523(1.21)  LDD0548  [13]
 LDCM0232  AC115 HCT 116 C523(1.50)  LDD0549  [13]
 LDCM0233  AC116 HCT 116 C523(1.30)  LDD0550  [13]
 LDCM0234  AC117 HCT 116 C523(1.01)  LDD0551  [13]
 LDCM0235  AC118 HCT 116 C523(1.02)  LDD0552  [13]
 LDCM0236  AC119 HCT 116 C523(1.30)  LDD0553  [13]
 LDCM0237  AC12 HCT 116 C523(1.13)  LDD0554  [13]
 LDCM0238  AC120 HCT 116 C523(1.37)  LDD0555  [13]
 LDCM0239  AC121 HCT 116 C523(1.14)  LDD0556  [13]
 LDCM0240  AC122 HCT 116 C523(1.11)  LDD0557  [13]
 LDCM0241  AC123 HCT 116 C523(1.13)  LDD0558  [13]
 LDCM0242  AC124 HCT 116 C523(0.98)  LDD0559  [13]
 LDCM0243  AC125 HCT 116 C523(1.06)  LDD0560  [13]
 LDCM0244  AC126 HCT 116 C523(1.41)  LDD0561  [13]
 LDCM0245  AC127 HCT 116 C523(1.47)  LDD0562  [13]
 LDCM0246  AC128 HCT 116 C523(1.10)  LDD0563  [13]
 LDCM0247  AC129 HCT 116 C523(0.72)  LDD0564  [13]
 LDCM0249  AC130 HCT 116 C523(0.93)  LDD0566  [13]
 LDCM0250  AC131 HCT 116 C523(0.80)  LDD0567  [13]
 LDCM0251  AC132 HCT 116 C523(0.72)  LDD0568  [13]
 LDCM0252  AC133 HCT 116 C523(0.88)  LDD0569  [13]
 LDCM0253  AC134 HCT 116 C523(0.94)  LDD0570  [13]
 LDCM0254  AC135 HCT 116 C523(0.86)  LDD0571  [13]
 LDCM0255  AC136 HCT 116 C523(0.86)  LDD0572  [13]
 LDCM0256  AC137 HCT 116 C523(0.95)  LDD0573  [13]
 LDCM0257  AC138 HCT 116 C523(1.12)  LDD0574  [13]
 LDCM0258  AC139 HCT 116 C523(1.08)  LDD0575  [13]
 LDCM0259  AC14 HCT 116 C523(1.17)  LDD0576  [13]
 LDCM0260  AC140 HCT 116 C523(0.96)  LDD0577  [13]
 LDCM0261  AC141 HCT 116 C523(0.89)  LDD0578  [13]
 LDCM0262  AC142 HCT 116 C523(0.80)  LDD0579  [13]
 LDCM0263  AC143 HCT 116 C523(1.28)  LDD0580  [13]
 LDCM0264  AC144 HCT 116 C523(1.53)  LDD0581  [13]
 LDCM0265  AC145 HCT 116 C523(1.28)  LDD0582  [13]
 LDCM0266  AC146 HCT 116 C523(1.31)  LDD0583  [13]
 LDCM0267  AC147 HCT 116 C523(1.45)  LDD0584  [13]
 LDCM0268  AC148 HCT 116 C523(2.28)  LDD0585  [13]
 LDCM0269  AC149 HCT 116 C523(1.68)  LDD0586  [13]
 LDCM0270  AC15 HCT 116 C523(1.35)  LDD0587  [13]
 LDCM0271  AC150 HCT 116 C523(1.12)  LDD0588  [13]
 LDCM0272  AC151 HCT 116 C523(1.10)  LDD0589  [13]
 LDCM0273  AC152 HCT 116 C523(1.62)  LDD0590  [13]
 LDCM0274  AC153 HCT 116 C523(2.75)  LDD0591  [13]
 LDCM0621  AC154 HCT 116 C523(1.48)  LDD2158  [13]
 LDCM0622  AC155 HCT 116 C523(1.69)  LDD2159  [13]
 LDCM0623  AC156 HCT 116 C523(1.09)  LDD2160  [13]
 LDCM0624  AC157 HCT 116 C523(1.20)  LDD2161  [13]
 LDCM0276  AC17 HCT 116 C523(1.09)  LDD0593  [13]
 LDCM0277  AC18 HCT 116 C523(1.60)  LDD0594  [13]
 LDCM0278  AC19 HCT 116 C523(1.41)  LDD0595  [13]
 LDCM0279  AC2 HCT 116 C523(0.96)  LDD0596  [13]
 LDCM0280  AC20 HCT 116 C523(1.25)  LDD0597  [13]
 LDCM0281  AC21 HCT 116 C523(1.45)  LDD0598  [13]
 LDCM0282  AC22 HCT 116 C523(1.17)  LDD0599  [13]
 LDCM0283  AC23 HCT 116 C523(1.04)  LDD0600  [13]
 LDCM0284  AC24 HCT 116 C523(1.08)  LDD0601  [13]
 LDCM0285  AC25 HCT 116 C523(1.29)  LDD0602  [13]
 LDCM0286  AC26 HCT 116 C523(1.51)  LDD0603  [13]
 LDCM0287  AC27 HCT 116 C523(1.52)  LDD0604  [13]
 LDCM0288  AC28 HCT 116 C523(1.74)  LDD0605  [13]
 LDCM0289  AC29 HCT 116 C523(1.72)  LDD0606  [13]
 LDCM0290  AC3 HCT 116 C523(0.85)  LDD0607  [13]
 LDCM0291  AC30 HCT 116 C523(1.78)  LDD0608  [13]
 LDCM0292  AC31 HCT 116 C523(1.48)  LDD0609  [13]
 LDCM0293  AC32 HCT 116 C523(2.44)  LDD0610  [13]
 LDCM0294  AC33 HCT 116 C523(1.81)  LDD0611  [13]
 LDCM0295  AC34 HCT 116 C523(2.05)  LDD0612  [13]
 LDCM0296  AC35 HCT 116 C523(0.83)  LDD0613  [13]
 LDCM0297  AC36 HCT 116 C523(0.89)  LDD0614  [13]
 LDCM0298  AC37 HCT 116 C523(0.89)  LDD0615  [13]
 LDCM0299  AC38 HCT 116 C523(1.02)  LDD0616  [13]
 LDCM0300  AC39 HCT 116 C523(1.08)  LDD0617  [13]
 LDCM0301  AC4 HCT 116 C523(1.05)  LDD0618  [13]
 LDCM0302  AC40 HCT 116 C523(1.21)  LDD0619  [13]
 LDCM0303  AC41 HCT 116 C523(1.12)  LDD0620  [13]
 LDCM0304  AC42 HCT 116 C523(1.01)  LDD0621  [13]
 LDCM0305  AC43 HCT 116 C523(1.37)  LDD0622  [13]
 LDCM0306  AC44 HCT 116 C523(1.16)  LDD0623  [13]
 LDCM0307  AC45 HCT 116 C523(1.36)  LDD0624  [13]
 LDCM0308  AC46 HCT 116 C523(1.05)  LDD0625  [13]
 LDCM0309  AC47 HCT 116 C523(1.03)  LDD0626  [13]
 LDCM0310  AC48 HCT 116 C523(1.04)  LDD0627  [13]
 LDCM0311  AC49 HCT 116 C523(1.85)  LDD0628  [13]
 LDCM0312  AC5 HCT 116 C523(0.92)  LDD0629  [13]
 LDCM0313  AC50 HCT 116 C523(1.94)  LDD0630  [13]
 LDCM0314  AC51 HCT 116 C523(0.96)  LDD0631  [13]
 LDCM0315  AC52 HCT 116 C523(1.13)  LDD0632  [13]
 LDCM0316  AC53 HCT 116 C523(1.40)  LDD0633  [13]
 LDCM0317  AC54 HCT 116 C523(1.44)  LDD0634  [13]
 LDCM0318  AC55 HCT 116 C523(2.12)  LDD0635  [13]
 LDCM0319  AC56 HCT 116 C523(4.89)  LDD0636  [13]
 LDCM0320  AC57 HCT 116 C523(1.56)  LDD0637  [13]
 LDCM0321  AC58 HCT 116 C523(1.80)  LDD0638  [13]
 LDCM0322  AC59 HCT 116 C523(1.71)  LDD0639  [13]
 LDCM0323  AC6 HCT 116 C523(1.32)  LDD0640  [13]
 LDCM0324  AC60 HCT 116 C523(1.44)  LDD0641  [13]
 LDCM0325  AC61 HCT 116 C523(1.33)  LDD0642  [13]
 LDCM0326  AC62 HCT 116 C523(1.82)  LDD0643  [13]
 LDCM0327  AC63 HCT 116 C523(1.59)  LDD0644  [13]
 LDCM0328  AC64 HCT 116 C523(1.71)  LDD0645  [13]
 LDCM0329  AC65 HCT 116 C523(1.17)  LDD0646  [13]
 LDCM0330  AC66 HCT 116 C523(1.24)  LDD0647  [13]
 LDCM0331  AC67 HCT 116 C523(1.60)  LDD0648  [13]
 LDCM0332  AC68 HCT 116 C523(1.07)  LDD0649  [13]
 LDCM0333  AC69 HCT 116 C523(1.20)  LDD0650  [13]
 LDCM0334  AC7 HCT 116 C523(1.10)  LDD0651  [13]
 LDCM0335  AC70 HCT 116 C523(1.31)  LDD0652  [13]
 LDCM0336  AC71 HCT 116 C523(0.93)  LDD0653  [13]
 LDCM0337  AC72 HCT 116 C523(1.26)  LDD0654  [13]
 LDCM0338  AC73 HCT 116 C523(1.84)  LDD0655  [13]
 LDCM0339  AC74 HCT 116 C523(1.40)  LDD0656  [13]
 LDCM0340  AC75 HCT 116 C523(2.29)  LDD0657  [13]
 LDCM0341  AC76 HCT 116 C523(1.14)  LDD0658  [13]
 LDCM0342  AC77 HCT 116 C523(1.49)  LDD0659  [13]
 LDCM0343  AC78 HCT 116 C523(1.13)  LDD0660  [13]
 LDCM0344  AC79 HCT 116 C523(1.37)  LDD0661  [13]
 LDCM0345  AC8 HCT 116 C523(1.51)  LDD0662  [13]
 LDCM0346  AC80 HCT 116 C523(1.24)  LDD0663  [13]
 LDCM0347  AC81 HCT 116 C523(1.14)  LDD0664  [13]
 LDCM0348  AC82 HCT 116 C523(2.09)  LDD0665  [13]
 LDCM0349  AC83 HCT 116 C523(1.65)  LDD0666  [13]
 LDCM0350  AC84 HCT 116 C523(1.53)  LDD0667  [13]
 LDCM0351  AC85 HCT 116 C523(1.26)  LDD0668  [13]
 LDCM0352  AC86 HCT 116 C523(1.07)  LDD0669  [13]
 LDCM0353  AC87 HCT 116 C523(1.02)  LDD0670  [13]
 LDCM0354  AC88 HCT 116 C523(1.10)  LDD0671  [13]
 LDCM0355  AC89 HCT 116 C523(1.33)  LDD0672  [13]
 LDCM0357  AC90 HCT 116 C523(0.96)  LDD0674  [13]
 LDCM0358  AC91 HCT 116 C523(1.83)  LDD0675  [13]
 LDCM0359  AC92 HCT 116 C523(1.68)  LDD0676  [13]
 LDCM0360  AC93 HCT 116 C523(1.49)  LDD0677  [13]
 LDCM0361  AC94 HCT 116 C523(1.41)  LDD0678  [13]
 LDCM0362  AC95 HCT 116 C523(1.18)  LDD0679  [13]
 LDCM0363  AC96 HCT 116 C523(1.33)  LDD0680  [13]
 LDCM0364  AC97 HCT 116 C523(1.94)  LDD0681  [13]
 LDCM0365  AC98 HCT 116 C523(2.50)  LDD0682  [13]
 LDCM0366  AC99 HCT 116 C523(0.90)  LDD0683  [13]
 LDCM0248  AKOS034007472 HCT 116 C523(1.04)  LDD0565  [13]
 LDCM0356  AKOS034007680 HCT 116 C523(1.23)  LDD0673  [13]
 LDCM0275  AKOS034007705 HCT 116 C523(2.45)  LDD0592  [13]
 LDCM0156  Aniline NCI-H1299 12.24  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C523(0.99)  LDD0078  [13]
 LDCM0630  CCW28-3 231MFP C523(0.91)  LDD2214  [28]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [23]
 LDCM0367  CL1 HCT 116 C523(0.80)  LDD0684  [13]
 LDCM0368  CL10 HCT 116 C523(1.18)  LDD0685  [13]
 LDCM0369  CL100 HCT 116 C523(1.05)  LDD0686  [13]
 LDCM0370  CL101 HCT 116 C523(1.24)  LDD0687  [13]
 LDCM0371  CL102 HCT 116 C523(0.97)  LDD0688  [13]
 LDCM0372  CL103 HCT 116 C523(0.95)  LDD0689  [13]
 LDCM0373  CL104 HCT 116 C523(1.01)  LDD0690  [13]
 LDCM0374  CL105 HCT 116 C523(1.20)  LDD0691  [13]
 LDCM0375  CL106 HCT 116 C523(1.82)  LDD0692  [13]
 LDCM0376  CL107 HCT 116 C523(1.43)  LDD0693  [13]
 LDCM0377  CL108 HCT 116 C523(1.53)  LDD0694  [13]
 LDCM0378  CL109 HCT 116 C523(1.25)  LDD0695  [13]
 LDCM0379  CL11 HCT 116 C523(1.67)  LDD0696  [13]
 LDCM0380  CL110 HCT 116 C523(1.30)  LDD0697  [13]
 LDCM0381  CL111 HCT 116 C523(1.15)  LDD0698  [13]
 LDCM0382  CL112 HCT 116 C523(1.15)  LDD0699  [13]
 LDCM0383  CL113 HCT 116 C523(2.31)  LDD0700  [13]
 LDCM0384  CL114 HCT 116 C523(1.47)  LDD0701  [13]
 LDCM0385  CL115 HCT 116 C523(1.63)  LDD0702  [13]
 LDCM0386  CL116 HCT 116 C523(1.41)  LDD0703  [13]
 LDCM0387  CL117 HCT 116 C523(2.41)  LDD0704  [13]
 LDCM0388  CL118 HCT 116 C523(0.99)  LDD0705  [13]
 LDCM0389  CL119 HCT 116 C523(1.17)  LDD0706  [13]
 LDCM0390  CL12 HCT 116 C523(2.34)  LDD0707  [13]
 LDCM0391  CL120 HCT 116 C523(1.14)  LDD0708  [13]
 LDCM0392  CL121 HCT 116 C523(1.29)  LDD0709  [13]
 LDCM0393  CL122 HCT 116 C523(1.05)  LDD0710  [13]
 LDCM0394  CL123 HCT 116 C523(1.11)  LDD0711  [13]
 LDCM0395  CL124 HCT 116 C523(1.41)  LDD0712  [13]
 LDCM0396  CL125 HCT 116 C523(1.02)  LDD0713  [13]
 LDCM0397  CL126 HCT 116 C523(1.14)  LDD0714  [13]
 LDCM0398  CL127 HCT 116 C523(1.02)  LDD0715  [13]
 LDCM0399  CL128 HCT 116 C523(1.81)  LDD0716  [13]
 LDCM0400  CL13 HCT 116 C523(1.64)  LDD0717  [13]
 LDCM0401  CL14 HCT 116 C523(0.89)  LDD0718  [13]
 LDCM0402  CL15 HCT 116 C523(1.12)  LDD0719  [13]
 LDCM0403  CL16 HCT 116 C523(1.12)  LDD0720  [13]
 LDCM0404  CL17 HCT 116 C523(0.94)  LDD0721  [13]
 LDCM0405  CL18 HCT 116 C523(1.20)  LDD0722  [13]
 LDCM0406  CL19 HCT 116 C523(1.24)  LDD0723  [13]
 LDCM0407  CL2 HCT 116 C523(0.75)  LDD0724  [13]
 LDCM0408  CL20 HCT 116 C523(1.55)  LDD0725  [13]
 LDCM0409  CL21 HCT 116 C523(1.67)  LDD0726  [13]
 LDCM0410  CL22 HCT 116 C523(4.01)  LDD0727  [13]
 LDCM0411  CL23 HCT 116 C523(1.51)  LDD0728  [13]
 LDCM0412  CL24 HCT 116 C523(2.10)  LDD0729  [13]
 LDCM0413  CL25 HCT 116 C523(1.48)  LDD0730  [13]
 LDCM0414  CL26 HCT 116 C523(1.26)  LDD0731  [13]
 LDCM0415  CL27 HCT 116 C523(1.34)  LDD0732  [13]
 LDCM0416  CL28 HCT 116 C523(1.47)  LDD0733  [13]
 LDCM0417  CL29 HCT 116 C523(1.73)  LDD0734  [13]
 LDCM0418  CL3 HCT 116 C523(0.90)  LDD0735  [13]
 LDCM0419  CL30 HCT 116 C523(1.30)  LDD0736  [13]
 LDCM0420  CL31 HCT 116 C523(1.04)  LDD0737  [13]
 LDCM0421  CL32 HCT 116 C523(1.21)  LDD0738  [13]
 LDCM0422  CL33 HCT 116 C523(1.14)  LDD0739  [13]
 LDCM0423  CL34 HCT 116 C523(1.61)  LDD0740  [13]
 LDCM0424  CL35 HCT 116 C523(1.76)  LDD0741  [13]
 LDCM0425  CL36 HCT 116 C523(1.42)  LDD0742  [13]
 LDCM0426  CL37 HCT 116 C523(1.92)  LDD0743  [13]
 LDCM0428  CL39 HCT 116 C523(1.55)  LDD0745  [13]
 LDCM0429  CL4 HCT 116 C523(0.88)  LDD0746  [13]
 LDCM0430  CL40 HCT 116 C523(1.38)  LDD0747  [13]
 LDCM0431  CL41 HCT 116 C523(1.33)  LDD0748  [13]
 LDCM0432  CL42 HCT 116 C523(2.84)  LDD0749  [13]
 LDCM0433  CL43 HCT 116 C523(2.30)  LDD0750  [13]
 LDCM0434  CL44 HCT 116 C523(1.53)  LDD0751  [13]
 LDCM0435  CL45 HCT 116 C523(1.99)  LDD0752  [13]
 LDCM0436  CL46 HCT 116 C523(0.72)  LDD0753  [13]
 LDCM0437  CL47 HCT 116 C523(0.72)  LDD0754  [13]
 LDCM0438  CL48 HCT 116 C523(0.69)  LDD0755  [13]
 LDCM0439  CL49 HCT 116 C523(0.84)  LDD0756  [13]
 LDCM0440  CL5 HCT 116 C523(0.98)  LDD0757  [13]
 LDCM0441  CL50 HCT 116 C523(0.67)  LDD0758  [13]
 LDCM0442  CL51 HCT 116 C523(0.78)  LDD0759  [13]
 LDCM0443  CL52 HCT 116 C523(0.90)  LDD0760  [13]
 LDCM0444  CL53 HCT 116 C523(0.90)  LDD0761  [13]
 LDCM0445  CL54 HCT 116 C523(0.81)  LDD0762  [13]
 LDCM0446  CL55 HCT 116 C523(0.77)  LDD0763  [13]
 LDCM0447  CL56 HCT 116 C523(0.87)  LDD0764  [13]
 LDCM0448  CL57 HCT 116 C523(0.67)  LDD0765  [13]
 LDCM0449  CL58 HCT 116 C523(0.81)  LDD0766  [13]
 LDCM0450  CL59 HCT 116 C523(0.94)  LDD0767  [13]
 LDCM0451  CL6 HCT 116 C523(0.95)  LDD0768  [13]
 LDCM0452  CL60 HCT 116 C523(0.78)  LDD0769  [13]
 LDCM0453  CL61 HCT 116 C523(0.96)  LDD0770  [13]
 LDCM0454  CL62 HCT 116 C523(0.94)  LDD0771  [13]
 LDCM0455  CL63 HCT 116 C523(1.15)  LDD0772  [13]
 LDCM0456  CL64 HCT 116 C523(1.34)  LDD0773  [13]
 LDCM0457  CL65 HCT 116 C523(1.10)  LDD0774  [13]
 LDCM0458  CL66 HCT 116 C523(1.80)  LDD0775  [13]
 LDCM0459  CL67 HCT 116 C523(1.54)  LDD0776  [13]
 LDCM0460  CL68 HCT 116 C523(1.31)  LDD0777  [13]
 LDCM0461  CL69 HCT 116 C523(0.97)  LDD0778  [13]
 LDCM0462  CL7 HCT 116 C523(1.85)  LDD0779  [13]
 LDCM0463  CL70 HCT 116 C523(1.32)  LDD0780  [13]
 LDCM0464  CL71 HCT 116 C523(1.38)  LDD0781  [13]
 LDCM0465  CL72 HCT 116 C523(1.06)  LDD0782  [13]
 LDCM0466  CL73 HCT 116 C523(1.35)  LDD0783  [13]
 LDCM0467  CL74 HCT 116 C523(1.44)  LDD0784  [13]
 LDCM0469  CL76 HCT 116 C523(1.11)  LDD0786  [13]
 LDCM0470  CL77 HCT 116 C523(0.94)  LDD0787  [13]
 LDCM0471  CL78 HCT 116 C523(1.33)  LDD0788  [13]
 LDCM0472  CL79 HCT 116 C523(1.89)  LDD0789  [13]
 LDCM0473  CL8 HCT 116 C523(2.30)  LDD0790  [13]
 LDCM0474  CL80 HCT 116 C523(1.03)  LDD0791  [13]
 LDCM0475  CL81 HCT 116 C523(1.28)  LDD0792  [13]
 LDCM0476  CL82 HCT 116 C523(3.27)  LDD0793  [13]
 LDCM0477  CL83 HCT 116 C523(1.67)  LDD0794  [13]
 LDCM0478  CL84 HCT 116 C523(3.17)  LDD0795  [13]
 LDCM0479  CL85 HCT 116 C523(1.09)  LDD0796  [13]
 LDCM0480  CL86 HCT 116 C523(0.90)  LDD0797  [13]
 LDCM0481  CL87 HCT 116 C523(1.05)  LDD0798  [13]
 LDCM0482  CL88 HCT 116 C523(1.65)  LDD0799  [13]
 LDCM0483  CL89 HCT 116 C523(4.54)  LDD0800  [13]
 LDCM0484  CL9 HCT 116 C523(1.18)  LDD0801  [13]
 LDCM0485  CL90 HCT 116 C523(0.66)  LDD0802  [13]
 LDCM0486  CL91 HCT 116 C523(1.07)  LDD0803  [13]
 LDCM0487  CL92 HCT 116 C523(0.96)  LDD0804  [13]
 LDCM0488  CL93 HCT 116 C523(0.86)  LDD0805  [13]
 LDCM0489  CL94 HCT 116 C523(1.02)  LDD0806  [13]
 LDCM0490  CL95 HCT 116 C523(0.98)  LDD0807  [13]
 LDCM0491  CL96 HCT 116 C523(1.13)  LDD0808  [13]
 LDCM0492  CL97 HCT 116 C523(0.93)  LDD0809  [13]
 LDCM0493  CL98 HCT 116 C523(1.02)  LDD0810  [13]
 LDCM0494  CL99 HCT 116 C523(1.02)  LDD0811  [13]
 LDCM0634  CY-0357 Hep-G2 C523(1.98)  LDD2228  [18]
 LDCM0495  E2913 HEK-293T C87(0.94)  LDD1698  [29]
 LDCM0625  F8 Ramos C523(1.95)  LDD2187  [30]
 LDCM0572  Fragment10 Ramos C523(0.99)  LDD2189  [30]
 LDCM0573  Fragment11 Ramos C523(0.42)  LDD2190  [30]
 LDCM0574  Fragment12 Ramos C523(0.81)  LDD2191  [30]
 LDCM0575  Fragment13 Ramos C523(1.22)  LDD2192  [30]
 LDCM0576  Fragment14 Ramos C523(1.31)  LDD2193  [30]
 LDCM0579  Fragment20 Ramos C523(0.69)  LDD2194  [30]
 LDCM0580  Fragment21 Ramos C523(1.07)  LDD2195  [30]
 LDCM0582  Fragment23 Ramos C523(1.19)  LDD2196  [30]
 LDCM0578  Fragment27 Ramos C523(1.13)  LDD2197  [30]
 LDCM0586  Fragment28 Ramos C523(0.79)  LDD2198  [30]
 LDCM0588  Fragment30 Ramos C523(1.42)  LDD2199  [30]
 LDCM0589  Fragment31 Ramos C523(1.13)  LDD2200  [30]
 LDCM0590  Fragment32 Ramos C523(1.06)  LDD2201  [30]
 LDCM0468  Fragment33 HCT 116 C523(1.33)  LDD0785  [13]
 LDCM0596  Fragment38 Ramos C523(1.06)  LDD2203  [30]
 LDCM0566  Fragment4 Ramos C523(1.04)  LDD2184  [30]
 LDCM0427  Fragment51 HCT 116 C523(3.10)  LDD0744  [13]
 LDCM0610  Fragment52 Ramos C523(1.50)  LDD2204  [30]
 LDCM0614  Fragment56 Ramos C523(1.23)  LDD2205  [30]
 LDCM0569  Fragment7 Ramos C523(1.35)  LDD2186  [30]
 LDCM0571  Fragment9 Ramos C523(0.92)  LDD2188  [30]
 LDCM0116  HHS-0101 DM93 Y390(0.81); Y524(0.88)  LDD0264  [11]
 LDCM0117  HHS-0201 DM93 Y524(0.65); Y390(0.68)  LDD0265  [11]
 LDCM0118  HHS-0301 DM93 Y390(0.78); Y524(0.83)  LDD0266  [11]
 LDCM0119  HHS-0401 DM93 Y390(0.71); Y524(0.97)  LDD0267  [11]
 LDCM0120  HHS-0701 DM93 Y390(0.72); Y524(0.73)  LDD0268  [11]
 LDCM0022  KB02 HCT 116 C523(1.57)  LDD0080  [13]
 LDCM0023  KB03 HCT 116 C523(0.87)  LDD0081  [13]
 LDCM0024  KB05 HCT 116 C523(1.34)  LDD0082  [13]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C373(0.98)  LDD2099  [5]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C373(0.34)  LDD2100  [5]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C373(0.65)  LDD2107  [5]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C373(0.70)  LDD2109  [5]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C373(0.41)  LDD2114  [5]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C373(0.42)  LDD2123  [5]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C373(0.73)  LDD2125  [5]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C373(0.93)  LDD2127  [5]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C373(0.41)  LDD2134  [5]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C373(1.39)  LDD2135  [5]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C373(0.63)  LDD2137  [5]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C373(0.49)  LDD2140  [5]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C373(0.40)  LDD2141  [5]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C373(0.64)  LDD2148  [5]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C245(0.36)  LDD2151  [5]
 LDCM0131  RA190 MM1.R 4.76  LDD0300  [10]
 LDCM0021  THZ1 HCT 116 C523(1.32)  LDD2173  [13]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Dystrobrevin beta (DTNB) Dystrophin family O60941
E3 SUMO-protein ligase NSE2 (NSMCE2) NSE2 family Q96MF7
Serine/threonine-protein kinase TBK1 (TBK1) Ser/Thr protein kinase family Q9UHD2
Transporter and channel
Click To Hide/Show 6 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Eukaryotic translation initiation factor 4E transporter (EIF4ENIF1) 4E-T/EIF4E-T family Q9NRA8
WASH complex subunit 3 (WASHC3) CCDC53 family Q9Y3C0
Leucine zipper putative tumor suppressor 1 (LZTS1) LZTS family Q9Y250
Nuclear pore glycoprotein p62 (NUP62) Nucleoporin NSP1/NUP62 family P37198
Syntaxin-1A (STX1A) Syntaxin family Q16623
TBC1 domain family member 1 (TBC1D1) . Q86TI0
Transcription factor
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cell division cycle 5-like protein (CDC5L) CEF1 family Q99459
REST corepressor 3 (RCOR3) CoREST family Q9P2K3
Transcription factor BTF3 (BTF3) NAC-beta family P20290
Transcription factor BTF3 homolog 4 (BTF3L4) NAC-beta family Q96K17
DNA methyltransferase 1-associated protein 1 (DMAP1) . Q9NPF5
Homeobox protein MOX-1 (MEOX1) . P50221
Homeobox protein MOX-2 (MEOX2) . P50222
Oligodendrocyte transcription factor 2 (OLIG2) . Q13516
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (SMARCE1) . Q969G3
Other
Click To Hide/Show 57 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Apoptosis-stimulating of p53 protein 1 (PPP1R13B) ASPP family Q96KQ4
Breast cancer metastasis-suppressor 1-like protein (BRMS1L) BRMS1 family Q5PSV4
Cerebellar degeneration-related protein 2 (CDR2) CDR2 family Q01850
Centrosomal protein of 63 kDa (CEP63) CEP63 family Q96MT8
Deuterosome assembly protein 1 (DEUP1) CEP63 family Q05D60
Cilia- and flagella-associated protein 53 (CFAP53) CFAP53 family Q96M91
Protein chibby homolog 2 (CBY2) Chibby family Q8NA61
Dynein regulatory complex subunit 4 (GAS8) DRC4 family O95995
Protein FAM81A (FAM81A) FAM81 family Q8TBF8
Protein FAM9A (FAM9A) FAM9 family Q8IZU1
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Golgin subfamily A member 6A (GOLGA6A) GOLGA6 family Q9NYA3
Golgi reassembly-stacking protein 2 (GORASP2) GORASP family Q9H8Y8
HAUS augmin-like complex subunit 3 (HAUS3) HAUS3 family Q68CZ6
Keratin, type I cuticular Ha1 (KRT31) Intermediate filament family Q15323
Keratin, type I cuticular Ha4 (KRT34) Intermediate filament family O76011
Keratin, type I cuticular Ha5 (KRT35) Intermediate filament family Q92764
Keratin, type I cuticular Ha8 (KRT38) Intermediate filament family O76015
Keratin, type I cytoskeletal 15 (KRT15) Intermediate filament family P19012
Keratin, type I cytoskeletal 20 (KRT20) Intermediate filament family P35900
Keratin, type I cytoskeletal 24 (KRT24) Intermediate filament family Q2M2I5
Keratin, type I cytoskeletal 27 (KRT27) Intermediate filament family Q7Z3Y8
Keratin, type I cytoskeletal 40 (KRT40) Intermediate filament family Q6A162
Keratin, type II cytoskeletal 75 (KRT75) Intermediate filament family O95678
Lebercilin (LCA5) LCA5 family Q86VQ0
Liprin-alpha-1 (PPFIA1) Liprin family Q13136
Colorectal mutant cancer protein (MCC) MCC family P23508
Harmonin-binding protein USHBP1 (USHBP1) MCC family Q8N6Y0
Mediator of RNA polymerase II transcription subunit 4 (MED4) Mediator complex subunit 4 family Q9NPJ6
Protein Mis18-alpha (MIS18A) Mis18 family Q9NYP9
Nascent polypeptide-associated complex subunit alpha (NACA) NAC-alpha family Q13765
Kinetochore protein NDC80 homolog (NDC80) NDC80/HEC1 family O14777
N-myc-interactor (NMI) NMI family Q13287
RAD50-interacting protein 1 (RINT1) RINT1 family Q6NUQ1
Suppressor of IKBKE 1 (SIKE1) SIKE family Q9BRV8
Vacuolar-sorting protein SNF8 (SNF8) SNF8 family Q96H20
Splicing regulatory glutamine/lysine-rich protein 1 (SREK1) Splicing factor SR family Q8WXA9
Stathmin-2 (STMN2) Stathmin family Q93045
Syntaxin-1B (STX1B) Syntaxin family P61266
Beta-taxilin (TXLNB) Taxilin family Q8N3L3
T-cell leukemia/lymphoma protein 1A (TCL1A) TCL1 family P56279
Tuftelin-interacting protein 11 (TFIP11) TFP11/STIP family Q9UBB9
Centrosomal protein CEP57L1 (CEP57L1) Translokin family Q8IYX8
U3 small nucleolar RNA-associated protein 14 homolog C (UTP14C) UTP14 family Q5TAP6
Vacuolar protein sorting-associated protein 52 homolog (VPS52) VPS52 family Q8N1B4
Axin-2 (AXIN2) . Q9Y2T1
Bridging integrator 3 (BIN3) . Q9NQY0
Centrosomal protein of 44 kDa (CEP44) . Q9C0F1
Coiled-coil domain-containing protein 146 (CCDC146) . Q8IYE0
Huntingtin-interacting protein K (HYPK) . Q9NX55
KN motif and ankyrin repeat domain-containing protein 2 (KANK2) . Q63ZY3
Protein hinderin (KIAA1328) . Q86T90
Tetratricopeptide repeat protein 33 (TTC33) . Q6PID6
TNFAIP3-interacting protein 1 (TNIP1) . Q15025
U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3) . O43395
Uncharacterized protein NKAPD1 (NKAPD1) . Q6ZUT1
Vinexin (SORBS3) . O60504

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
3 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
4 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
5 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
6 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
7 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
8 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
9 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
10 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.
11 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
12 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
13 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
14 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
15 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
16 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
17 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
18 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
19 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
20 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
21 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
22 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
23 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
24 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
25 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
26 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
27 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
28 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
29 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
30 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578