Details of the Target

General Information of Target

Target ID LDTP09081
Target Name SERPINE1 mRNA-binding protein 1 (SERBP1)
Gene Name SERBP1
Gene ID 26135
Synonyms
PAIRBP1; SERPINE1 mRNA-binding protein 1; PAI1 RNA-binding protein 1; PAI-RBP1; Plasminogen activator inhibitor 1 RNA-binding protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQK
QISYNYSDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD
RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG
DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
Target Bioclass
Other
Subcellular location
Cytoplasm
Function
Ribosome-binding protein that promotes ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation. Acts via its association with EEF2/eEF2 factor, sequestering EEF2/eEF2 at the A-site of the ribosome and promoting ribosome stabilization and storage in an inactive state. May also play a role in the regulation of mRNA stability: binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation.
Uniprot ID
Q8NC51
Ensemble ID
ENST00000361219.11
HGNC ID
HGNC:17860

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 48 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
A-EBA
 Probe Info  		50.00  LDD0214  [1]
m-APA
 Probe Info  		8.28  LDD0402  [2]
P1
 Probe Info  		10.00  LDD0448  [3]
CY-1
 Probe Info  		100.00  LDD0243  [4]
W1
 Probe Info  		13.23  LDD0235  [5]
TH211
 Probe Info  		Y207(20.00)  LDD0260  [6]
C-Sul
 Probe Info  		6.39  LDD0066  [7]
TH216
 Probe Info  		Y207(18.13)  LDD0259  [6]
YN-1
 Probe Info  		100.00  LDD0444  [8]
AZ-9
 Probe Info  		E7(1.11)  LDD2208  [9]
ONAyne
 Probe Info  		K299(0.00); K52(0.00); K303(0.00); K122(0.00)  LDD0273  [10]
OPA-S-S-alkyne
 Probe Info  		K76(1.17); K72(1.17); K303(2.74); K68(5.36)  LDD3494  [11]
Probe 1
 Probe Info  		Y244(12,350.22)  LDD3495  [12]
BTD
 Probe Info  		C11(1.01)  LDD1700  [13]
HHS-475
 Probe Info  		Y207(0.72)  LDD0264  [14]
HHS-465
 Probe Info  		Y207(10.00)  LDD2237  [15]
5E-2FA
 Probe Info  		H4(0.00); H343(0.00); H342(0.00); H334(0.00)  LDD2235  [16]
AMP probe
 Probe Info  		K122(0.00); K68(0.00); K310(0.00)  LDD0200  [17]
ATP probe
 Probe Info  		K122(0.00); K68(0.00); K310(0.00); K321(0.00)  LDD0199  [17]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [18]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [19]
IPIAA_H
 Probe Info  		N.A.  LDD0030  [20]
IPIAA_L
 Probe Info  		N.A.  LDD0031  [20]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [18]
ATP probe
 Probe Info  		K68(0.00); K329(0.00); K32(0.00)  LDD0035  [21]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [22]
NAIA_4
 Probe Info  		N.A.  LDD2226  [23]
TFBX
 Probe Info  		N.A.  LDD0027  [22]
WYneN
 Probe Info  		N.A.  LDD0021  [24]
WYneO
 Probe Info  		N.A.  LDD0022  [24]
DA-P3
 Probe Info  		N.A.  LDD0178  [25]
1d-yne
 Probe Info  		K68(0.00); K329(0.00)  LDD0356  [26]
ENE
 Probe Info  		N.A.  LDD0006  [24]
IPM
 Probe Info  		N.A.  LDD0005  [24]
NHS
 Probe Info  		K39(0.00); K52(0.00); K310(0.00); K68(0.00)  LDD0010  [24]
PPMS
 Probe Info  		N.A.  LDD0008  [24]
SF
 Probe Info  		K299(0.00); Y207(0.00); K303(0.00); K321(0.00)  LDD0028  [27]
STPyne
 Probe Info  		K39(0.00); K102(0.00); K68(0.00); K52(0.00)  LDD0009  [24]
VSF
 Probe Info  		N.A.  LDD0007  [24]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [28]
Ox-W18
 Probe Info  		W224(0.00); W319(0.00)  LDD2175  [29]
1c-yne
 Probe Info  		K39(0.00); K52(0.00); K303(0.00)  LDD0228  [26]
Acrolein
 Probe Info  		C11(0.00); H343(0.00); H342(0.00); H206(0.00)  LDD0217  [30]
Crotonaldehyde
 Probe Info  		H342(0.00); H196(0.00); C11(0.00)  LDD0219  [30]
Methacrolein
 Probe Info  		N.A.  LDD0218  [30]
AOyne
 Probe Info  		12.90  LDD0443  [31]
NAIA_5
 Probe Info  		N.A.  LDD2223  [23]
HHS-482
 Probe Info  		Y207(1.09)  LDD2239  [15]
PAL-AfBPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe13
 Probe Info  		8.41  LDD0475  [32]
FFF probe2
 Probe Info  		5.90  LDD0463  [32]
FFF probe3
 Probe Info  		5.20  LDD0464  [32]
FFF probe9
 Probe Info  		5.61  LDD0470  [32]
DA-2
 Probe Info  		N.A.  LDD0073  [33]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C11(0.95)  LDD2142  [13]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C11(0.93)  LDD2112  [13]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C11(0.91)  LDD2117  [13]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C11(1.06)  LDD2152  [13]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C11(0.94)  LDD2103  [13]
 LDCM0520  AKOS000195272 MDA-MB-231 C11(0.90)  LDD2113  [13]
 LDCM0156  Aniline NCI-H1299 11.51  LDD0403  [2]
 LDCM0498  BS-3668 MDA-MB-231 C11(1.24)  LDD2091  [13]
 LDCM0108  Chloroacetamide HeLa C11(0.00); H343(0.00); H4(0.00); H342(0.00)  LDD0222  [30]
 LDCM0632  CL-Sc Hep-G2 C11(0.64)  LDD2227  [23]
 LDCM0634  CY-0357 Hep-G2 C11(0.60)  LDD2228  [23]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C11(1.34)  LDD1702  [13]
 LDCM0625  F8 Ramos C11(1.54)  LDD2187  [34]
 LDCM0572  Fragment10 Ramos C11(1.38)  LDD2189  [34]
 LDCM0573  Fragment11 Ramos C11(0.07)  LDD2190  [34]
 LDCM0574  Fragment12 Ramos C11(2.01)  LDD2191  [34]
 LDCM0575  Fragment13 Ramos C11(1.21)  LDD2192  [34]
 LDCM0576  Fragment14 Ramos C11(0.91)  LDD2193  [34]
 LDCM0579  Fragment20 Ramos C11(1.50)  LDD2194  [34]
 LDCM0580  Fragment21 Ramos C11(1.25)  LDD2195  [34]
 LDCM0582  Fragment23 Ramos C11(2.31)  LDD2196  [34]
 LDCM0578  Fragment27 Ramos C11(1.22)  LDD2197  [34]
 LDCM0586  Fragment28 Ramos C11(1.09)  LDD2198  [34]
 LDCM0588  Fragment30 Ramos C11(2.03)  LDD2199  [34]
 LDCM0589  Fragment31 Ramos C11(1.09)  LDD2200  [34]
 LDCM0590  Fragment32 Ramos C11(4.37)  LDD2201  [34]
 LDCM0468  Fragment33 Ramos C11(1.13)  LDD2202  [34]
 LDCM0596  Fragment38 Ramos C11(1.31)  LDD2203  [34]
 LDCM0566  Fragment4 Ramos C11(2.71)  LDD2184  [34]
 LDCM0610  Fragment52 Ramos C11(0.93)  LDD2204  [34]
 LDCM0614  Fragment56 Ramos C11(1.04)  LDD2205  [34]
 LDCM0569  Fragment7 Ramos C11(0.74)  LDD2186  [34]
 LDCM0571  Fragment9 Ramos C11(1.23)  LDD2188  [34]
 LDCM0116  HHS-0101 DM93 Y207(0.72)  LDD0264  [14]
 LDCM0117  HHS-0201 DM93 Y207(1.12)  LDD0265  [14]
 LDCM0118  HHS-0301 DM93 Y207(1.05)  LDD0266  [14]
 LDCM0119  HHS-0401 DM93 Y207(1.42)  LDD0267  [14]
 LDCM0120  HHS-0701 DM93 Y207(1.29)  LDD0268  [14]
 LDCM0107  IAA HeLa C11(0.00); H342(0.00); H343(0.00); H206(0.00)  LDD0221  [30]
 LDCM0022  KB02 Ramos C11(0.88)  LDD2182  [34]
 LDCM0023  KB03 MDA-MB-231 C11(1.77)  LDD1701  [13]
 LDCM0024  KB05 Ramos C11(0.64)  LDD2185  [34]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C11(0.89)  LDD2102  [13]
 LDCM0109  NEM HeLa H343(0.00); H342(0.00); H206(0.00); H4(0.00)  LDD0223  [30]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C11(1.28)  LDD2090  [13]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C11(0.81)  LDD2092  [13]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C11(1.00)  LDD2094  [13]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C11(1.02)  LDD2096  [13]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C11(1.02)  LDD2097  [13]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C11(0.77)  LDD2098  [13]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C11(0.80)  LDD2100  [13]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C11(1.16)  LDD2101  [13]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C11(0.86)  LDD2104  [13]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C11(1.27)  LDD2105  [13]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C11(0.83)  LDD2106  [13]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C11(0.88)  LDD2108  [13]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C11(1.35)  LDD2109  [13]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C11(2.14)  LDD2110  [13]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C11(1.06)  LDD2111  [13]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C11(0.82)  LDD2114  [13]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C11(0.73)  LDD2115  [13]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C11(1.05)  LDD2116  [13]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C11(1.12)  LDD2118  [13]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C11(2.96)  LDD2119  [13]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C11(0.81)  LDD2120  [13]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C11(1.31)  LDD2122  [13]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C11(0.67)  LDD2123  [13]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C11(1.18)  LDD2124  [13]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C11(1.07)  LDD2125  [13]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C11(1.07)  LDD2126  [13]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C11(0.81)  LDD2127  [13]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C11(0.83)  LDD2128  [13]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C11(0.95)  LDD2129  [13]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C11(0.74)  LDD2133  [13]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C11(0.89)  LDD2134  [13]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C11(0.83)  LDD2135  [13]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C11(1.27)  LDD2136  [13]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C11(1.01)  LDD1700  [13]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C11(0.95)  LDD2140  [13]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C11(0.58)  LDD2141  [13]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C11(0.90)  LDD2143  [13]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C11(2.89)  LDD2144  [13]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C11(1.11)  LDD2146  [13]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C11(1.91)  LDD2147  [13]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C11(0.57)  LDD2148  [13]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C11(1.42)  LDD2149  [13]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C11(1.26)  LDD2151  [13]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C11(1.52)  LDD2153  [13]
 LDCM0627  NUDT7-COV-1 HEK-293T C11(0.98)  LDD2206  [35]
 LDCM0628  OTUB2-COV-1 HEK-293T C11(0.88); C11(0.15)  LDD2207  [35]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
TGF-beta receptor type-2 (TGFBR2) TKL Ser/Thr protein kinase family P37173
Chromodomain-helicase-DNA-binding protein 3 (CHD3) SNF2/RAD54 helicase family Q12873
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Platelet endothelial cell adhesion molecule (PECAM1) . P16284
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Serpin H1 (SERPINH1) Serpin family P50454
PRKCA-binding protein (PICK1) . Q9NRD5

References

1 2-Ethynylbenzaldehyde-Based, Lysine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Nonkinases. J Am Chem Soc. 2023 Feb 12. doi: 10.1021/jacs.2c11595. Online ahead of print.
Mass spectrometry data entry: PXD037665
2 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
3 Comparison of Different Competitive Proteome Profiling Approaches in Target Identification of Covalent Inhibitors. Chembiochem. 2022 Dec 16;23(24):e202200389. doi: 10.1002/cbic.202200389. Epub 2022 Nov 22.
4 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
5 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
6 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
7 Low-Toxicity Sulfonium-Based Probes for Cysteine-Specific Profiling in Live Cells. Anal Chem. 2022 Mar 15;94(10):4366-4372. doi: 10.1021/acs.analchem.1c05129. Epub 2022 Mar 4.
8 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
9 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells. J Am Chem Soc. 2020 Apr 1;142(13):6051-6059. doi: 10.1021/jacs.9b12116. Epub 2020 Mar 23.
10 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
11 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
12 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
13 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
14 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
15 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
16 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
17 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
18 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
19 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
20 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647
21 Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer. J Proteome Res. 2018 Jan 5;17(1):63-75. doi: 10.1021/acs.jproteome.7b00329. Epub 2017 Nov 22.
Mass spectrometry data entry: PXD006095 , PXD006096
22 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
23 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
24 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
25 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
26 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
27 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
28 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
29 Oxidative cyclization reagents reveal tryptophan cation- interactions. Nature. 2024 Mar;627(8004):680-687. doi: 10.1038/s41586-024-07140-6. Epub 2024 Mar 6.
Mass spectrometry data entry: PXD001377 , PXD005252
30 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
31 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
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Mass spectrometry data entry: PXD027578
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