Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | A-EBA | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 0.2 uM | |||||
| Criteria | Quantification: Probe vs DMSO | |||||
| Quantitative Method |
LFQ
|
|||||
| In Vivo Experiment Model | Model Type |
|
Cell lysate | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Chronic myeloid leukemia [ICD-11:2A20] | |||||
| Model Name | Human chronic myeloid leukemia cell lysate (K562) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00491 | Aurora kinase A (AURKA) | 50.0 | ||||
| LDTP05244 | Cyclin-dependent kinase 6 (CDK6) | 50.0 | ||||
| LDTP02770 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) | 50.0 | ||||
| LDTP00747 | Mitogen-activated protein kinase kinase kinase 7 (MAP3K7) | 50.0 | ||||
| LDTP06100 | Protein-tyrosine kinase 2-beta (PTK2B) | 50.0 | ||||
| LDTP06384 | Ribosomal protein S6 kinase alpha-1 (RPS6KA1) | 50.0 | ||||
| LDTP05733 | Serine/threonine-protein kinase 4 (STK4) | 50.0 | ||||
| LDTP05064 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) | 50.0 | ||||
| LDTP11819 | STE20-like serine/threonine-protein kinase (SLK) | 50.0 | ||||
| LDTP13446 | TRAF2 and NCK-interacting protein kinase (TNIK) | 50.0 | ||||
| LDTP11074 | Tubulin alpha-1C chain (TUBA1C) | 50.0 | ||||
| LDTP03299 | Cyclin-dependent kinase 2 (CDK2) | 10.4 | ||||
| LDTP05478 | Tyrosine-protein kinase BTK (BTK) | 9.8 | ||||
| LDTP01127 | Rho-associated protein kinase 2 (ROCK2) | 3.7 | ||||
| LDTP01784 | Tyrosine-protein kinase ABL1 (ABL1) | 3.6 | ||||
| LDTP03679 | Dual specificity protein kinase TTK (TTK) | 3.1 | ||||
| LDTP04882 | Ribose-phosphate pyrophosphokinase 1 (PRPS1) | 2.3 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02199 | Annexin A2 (ANXA2) | 50.0 | ||||
| LDTP05056 | Eukaryotic translation initiation factor 5A-1 (EIF5A) | 50.0 | ||||
Transcription factor
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03903 | Signal transducer and activator of transcription 3 (STAT3) | 2.4 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP04127 | F-actin-capping protein subunit beta (CAPZB) | 50.0 | ||||
| LDTP04385 | Lipopolysaccharide-responsive and beige-like anchor protein (LRBA) | 50.0 | ||||
| LDTP09081 | SERPINE1 mRNA-binding protein 1 (SERBP1) | 50.0 | ||||
| LDTP04684 | Nucleosome assembly protein 1-like 1 (NAP1L1) | 2.0 | ||||