Details of the Probe

General Information of Probe

Probe ID
LDPC0142
Probe Name
A-EBA
Probe Type
ABPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 448.482
Lipid-water partition coefficient (xlogp) 3.7995
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C27H20N4O3
Canonical SMILES
C#CCN(C)C(=O)c1cncc(-c2cnc3[nH]cc(-c4cc(C=O)c(C#C)cc4OC)c3c2)c1
InChI
InChI=1S/C27H20N4O3/c1-5-7-31(3)27(33)20-8-18(12-28-13-20)19-9-23-24(15-30-26(23)29-14-19)22-10-21(16-32)17(6-2)11-25(22)34-4/h1-2,8-16H,7H2,3-4H3,(H,29,30)
InChIKey
RBNIMBYYMAPEKV-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

265 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) LDTP06286 2.89  LDD0215 
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) LDTP10869 3.46  LDD0215 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 3.77  LDD0215 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 3.66  LDD0215 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 3.74  LDD0215 
26S proteasome non-ATPase regulatory subunit 5 (PSMD5) LDTP06532 3.34  LDD0215 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 2.81  LDD0215 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 2.45  LDD0215 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 4.68  LDD0215 
26S proteasome regulatory subunit 8 (PSMC5) LDTP04963 3.57  LDD0215 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 3.52  LDD0215 
5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1) LDTP05761 17.47  LDD0215 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 4.02  LDD0215 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 3.25  LDD0215 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 7.09  LDD0215 
7SK snRNA methylphosphate capping enzyme (MEPCE) LDTP07948 4.68  LDD0215 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 2.83  LDD0215 
Aconitate hydratase, mitochondrial (ACO2) LDTP10982 3.12  LDD0215 
Adenine phosphoribosyltransferase (APRT) LDTP02220 7.42  LDD0215 
Adenosylhomocysteinase (AHCY) LDTP03242 3.68  LDD0215 
Adenylate kinase 2, mitochondrial (AK2) LDTP04636 4.67  LDD0215 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 3.15  LDD0215 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 4.26  LDD0215 
Aldo-keto reductase family 1 member A1 (AKR1A1) LDTP02729 4.68  LDD0215 
Alpha-enolase (ENO1) LDTP02159 3.75  LDD0215 
Aminopeptidase B (RNPEP) LDTP15993 3.45  LDD0215 
Anaphase-promoting complex subunit 7 (ANAPC7) LDTP13409 4.61  LDD0215 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 2.91  LDD0215 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 4.00  LDD0215 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 3.15  LDD0215 
Aspartate aminotransferase, cytoplasmic (GOT1) LDTP02888 3.47  LDD0215 
Aspartate aminotransferase, mitochondrial (GOT2) LDTP01783 4.97  LDD0215 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 2.98  LDD0215 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 2.25  LDD0215 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 4.04  LDD0215 
ATP-citrate synthase (ACLY) LDTP04561 4.33  LDD0215 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 3.93  LDD0215 
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) LDTP05314 2.65  LDD0215 
ATP-dependent RNA helicase A (DHX9) LDTP05550 3.01  LDD0215 
ATP-dependent RNA helicase DDX1 (DDX1) LDTP09766 5.98  LDD0215 
ATP-dependent RNA helicase DDX3X (DDX3X) LDTP00314 3.18  LDD0215 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 3.49  LDD0215 
Aurora kinase A (AURKA) LDTP00491 50.00  LDD0214 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 3.77  LDD0215 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 4.01  LDD0215 
Biliverdin reductase A (BLVRA) LDTP04552 4.63  LDD0215 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 3.24  LDD0215 
Calcyclin-binding protein (CACYBP) LDTP12163 5.08  LDD0215 
Calpain-1 catalytic subunit (CAPN1) LDTP02204 3.87  LDD0215 
Carboxymethylenebutenolidase homolog (CMBL) LDTP10215 4.09  LDD0215 
Casein kinase II subunit alpha (CSNK2A1) LDTP05077 6.66  LDD0215 
Catalase (CAT) LDTP02001 3.67  LDD0215 
Chromodomain-helicase-DNA-binding protein 4 (CHD4) LDTP06219 3.65  LDD0215 
Citrate synthase, mitochondrial (CS) LDTP01205 3.79  LDD0215 
Creatine kinase B-type (CKB) LDTP02616 3.67  LDD0215 
CTP synthase 1 (CTPS1) LDTP02922 3.16  LDD0215 
Cullin-2 (CUL2) LDTP05947 2.84  LDD0215 
Cullin-associated NEDD8-dissociated protein 1 (CAND1) LDTP08296 3.18  LDD0215 
Cyclin-dependent kinase 1 (CDK1) LDTP02149 10.26  LDD0215 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 10.40  LDD0214 
Cyclin-dependent kinase 6 (CDK6) LDTP05244 50.00  LDD0214 
Cystathionine beta-synthase (CBS) LDTP03753 3.70  LDD0215 
Cytosol aminopeptidase (LAP3) LDTP03455 3.03  LDD0215 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 3.43  LDD0215 
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) LDTP03669 4.47  LDD0215 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 4.40  LDD0215 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 4.73  LDD0215 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 3.44  LDD0215 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 3.98  LDD0215 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 2.70  LDD0215 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 2.96  LDD0215 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 3.74  LDD0215 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 2.05  LDD0215 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 3.39  LDD0215 
DNA-directed RNA polymerase II subunit RPB1 (POLR2A) LDTP03298 2.45  LDD0215 
DNA-directed RNA polymerase II subunit RPB2 (POLR2B) LDTP03564 3.38  LDD0215 
Dual specificity protein kinase TTK (TTK) LDTP03679 3.07  LDD0214 
Dynamin-2 (DNM2) LDTP04374 2.85  LDD0215 
E3 SUMO-protein ligase RanBP2 (RANBP2) LDTP04310 2.70  LDD0215 
E3 ubiquitin-protein ligase HUWE1 (HUWE1) LDTP08135 2.77  LDD0215 
E3 ubiquitin-protein ligase RBBP6 (RBBP6) LDTP08116 3.54  LDD0215 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 3.36  LDD0215 
E3 ubiquitin-protein ligase UBR5 (UBR5) LDTP01495 3.35  LDD0215 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 4.93  LDD0215 
Elongation factor 2 (EEF2) LDTP02672 4.00  LDD0215 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 3.32  LDD0215 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 4.17  LDD0215 
Eukaryotic elongation factor 2 kinase (EEF2K) LDTP00268 5.02  LDD0215 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 3.52  LDD0215 
Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 3.49  LDD0215 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 50.00  LDD0214 
Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) LDTP03915 3.64  LDD0215 
Eukaryotic translation initiation factor 5B (EIF5B) LDTP01063 5.53  LDD0215 
Fatty acid synthase (FASN) LDTP04243 3.45  LDD0215 
Ferritin heavy chain (FTH1) LDTP01974 3.44  LDD0215 
Ferrochelatase, mitochondrial (FECH) LDTP03198 3.32  LDD0215 
Flap endonuclease 1 (FEN1) LDTP03872 3.47  LDD0215 
Flavin reductase (NADPH) (BLVRB) LDTP03511 3.55  LDD0215 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 4.52  LDD0215 
Fructose-bisphosphate aldolase C (ALDOC) LDTP02386 4.10  LDD0215 
Fumarate hydratase, mitochondrial (FH) LDTP02235 2.84  LDD0215 
Fumarylacetoacetase (FAH) LDTP02868 4.37  LDD0215 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 3.37  LDD0215 
Glucose-6-phosphate isomerase (GPI) LDTP02162 3.01  LDD0215 
Glutamine--tRNA ligase (QARS1) LDTP04135 3.61  LDD0215 
Glutaredoxin-3 (GLRX3) LDTP01374 3.93  LDD0215 
Glutathione reductase, mitochondrial (GSR) LDTP01771 4.43  LDD0215 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 6.33  LDD0215 
Glutathione S-transferase P (GSTP1) LDTP02333 4.01  LDD0215 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 3.60  LDD0215 
Glycine--tRNA ligase (GARS1) LDTP03946 2.89  LDD0215 
Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) LDTP03537 4.33  LDD0215 
GTP-binding nuclear protein Ran (RAN) LDTP05007 3.69  LDD0215 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 4.22  LDD0215 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 3.61  LDD0215 
Hexokinase-1 (HK1) LDTP02991 2.97  LDD0215 
Hexokinase-2 (HK2) LDTP04531 2.53  LDD0215 
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) LDTP05301 3.55  LDD0215 
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) LDTP01782 5.89  LDD0215 
Inorganic pyrophosphatase (PPA1) LDTP14854 4.42  LDD0215 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 4.26  LDD0215 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 3.15  LDD0215 
Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) LDTP06006 3.72  LDD0215 
Kinesin-like protein KIF2C (KIF2C) LDTP10935 2.80  LDD0215 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 4.01  LDD0215 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 3.40  LDD0215 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 3.01  LDD0215 
Leucine-rich repeat-containing protein 47 (LRRC47) LDTP15404 3.62  LDD0215 
Lon protease homolog, mitochondrial (LONP1) LDTP03817 2.66  LDD0215 
Lysine--tRNA ligase (KARS1) LDTP06294 2.70  LDD0215 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 3.64  LDD0215 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 4.52  LDD0215 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 4.53  LDD0215 
Methionine aminopeptidase 2 (METAP2) LDTP04375 4.87  LDD0215 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 3.17  LDD0215 
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCC1) LDTP10776 3.36  LDD0215 
Mitogen-activated protein kinase 1 (MAPK1) LDTP03445 3.71  LDD0215 
Mitogen-activated protein kinase kinase kinase 7 (MAP3K7) LDTP00747 50.00  LDD0214 
Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) LDTP01685 6.00  LDD0215 
Multifunctional protein CAD (CAD) LDTP03401 3.77  LDD0215 
Myosin-10 (MYH10) LDTP03765 2.85  LDD0215 
Myosin-9 (MYH9) LDTP03764 2.57  LDD0215 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 6.05  LDD0215 
Nardilysin (NRDC) LDTP00886 3.99  LDD0215 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 4.86  LDD0215 
Nucleolar RNA helicase 2 (DDX21) LDTP12469 3.27  LDD0215 
Obg-like ATPase 1 (OLA1) LDTP12610 6.78  LDD0215 
Ornithine aminotransferase, mitochondrial (OAT) LDTP02021 4.11  LDD0215 
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) LDTP03813 5.61  LDD0215 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 4.30  LDD0215 
Peptidyl-prolyl cis-trans isomerase B (PPIB) LDTP03216 3.40  LDD0215 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 3.59  LDD0215 
Peptidyl-prolyl cis-trans isomerase FKBP5 (FKBP5) LDTP05877 3.50  LDD0215 
Peroxiredoxin-1 (PRDX1) LDTP05503 3.68  LDD0215 
Peroxiredoxin-2 (PRDX2) LDTP03626 5.22  LDD0215 
Peroxiredoxin-4 (PRDX4) LDTP05773 2.95  LDD0215 
Peroxiredoxin-6 (PRDX6) LDTP03510 4.73  LDD0215 
Peroxisomal multifunctional enzyme type 2 (HSD17B4) LDTP04440 3.29  LDD0215 
Phenylalanine--tRNA ligase alpha subunit (FARSA) LDTP13831 5.44  LDD0215 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 4.89  LDD0215 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 3.32  LDD0215 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 4.93  LDD0215 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 3.12  LDD0215 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 3.31  LDD0215 
Platelet-activating factor acetylhydrolase IB subunit alpha1 (PAFAH1B3) LDTP06315 4.55  LDD0215 
Porphobilinogen deaminase (HMBS) LDTP02273 3.24  LDD0215 
Pre-mRNA-processing factor 19 (PRPF19) LDTP13623 2.28  LDD0215 
Pre-rRNA-processing protein TSR1 homolog (TSR1) LDTP14888 2.25  LDD0215 
Probable ATP-dependent RNA helicase DDX17 (DDX17) LDTP09899 17.36  LDD0215 
Probable ATP-dependent RNA helicase DDX46 (DDX46) LDTP07932 4.04  LDD0215 
Probable ATP-dependent RNA helicase DDX5 (DDX5) LDTP02924 3.40  LDD0215 
Probable ATP-dependent RNA helicase DDX6 (DDX6) LDTP03348 3.52  LDD0215 
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) LDTP09961 4.66  LDD0215 
Proliferation-associated protein 2G4 (PA2G4) LDTP13750 4.44  LDD0215 
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) LDTP02095 3.77  LDD0215 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 4.71  LDD0215 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 3.54  LDD0215 
Proteasome subunit alpha type-2 (PSMA2) LDTP03331 4.38  LDD0215 
Proteasome subunit alpha type-4 (PSMA4) LDTP03333 3.25  LDD0215 
Proteasome subunit alpha type-5 (PSMA5) LDTP03413 3.89  LDD0215 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 5.72  LDD0215 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 3.35  LDD0215 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 3.08  LDD0215 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 5.62  LDD0215 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 3.45  LDD0215 
Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 4.28  LDD0215 
Protein disulfide-isomerase (P4HB) LDTP02188 3.42  LDD0215 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 3.05  LDD0215 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 3.99  LDD0215 
Protein disulfide-isomerase A6 (PDIA6) LDTP06314 3.45  LDD0215 
Protein phosphatase 1G (PPM1G) LDTP00616 3.36  LDD0215 
Protein phosphatase methylesterase 1 (PPME1) LDTP14092 5.04  LDD0215 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 3.63  LDD0215 
Protein-tyrosine kinase 2-beta (PTK2B) LDTP06100 50.00  LDD0214 
Purine nucleoside phosphorylase (PNP) LDTP01781 6.56  LDD0215 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 3.43  LDD0215 
Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) LDTP03644 4.31  LDD0215 
Pyrroline-5-carboxylate reductase 2 (PYCR2) LDTP10159 4.10  LDD0215 
Pyruvate carboxylase, mitochondrial (PC) LDTP02576 3.54  LDD0215 
Pyruvate kinase PKLR (PKLR) LDTP03552 3.40  LDD0215 
Pyruvate kinase PKM (PKM) LDTP02733 3.92  LDD0215 
Quinone oxidoreductase (CRYZ) LDTP05551 3.33  LDD0215 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 3.28  LDD0215 
Ras-related protein Rab-1B (RAB1B) LDTP11733 5.91  LDD0215 
Ras-related protein Rap-1b (RAP1B) LDTP04910 4.84  LDD0215 
Regulator of nonsense transcripts 1 (UPF1) LDTP09921 3.78  LDD0215 
Retinal dehydrogenase 2 (ALDH1A2) LDTP01419 4.08  LDD0215 
Rho-associated protein kinase 2 (ROCK2) LDTP01127 3.66  LDD0214 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 2.46  LDD0215 
Ribose-phosphate pyrophosphokinase 1 (PRPS1) LDTP04882 2.34  LDD0214 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 50.00  LDD0214 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 3.63  LDD0215 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 4.78  LDD0215 
RuvB-like 1 (RUVBL1) LDTP13816 4.84  LDD0215 
RuvB-like 2 (RUVBL2) LDTP13787 3.04  LDD0215 
S-formylglutathione hydrolase (ESD) LDTP02521 4.85  LDD0215 
Septin-11 (SEPTIN11) LDTP12667 4.87  LDD0215 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 4.75  LDD0215 
Serine--tRNA ligase, cytoplasmic (SARS1) LDTP04265 5.23  LDD0215 
Serine/threonine-protein kinase 4 (STK4) LDTP05733 50.00  LDD0214 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 2.92  LDD0215 
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) LDTP05064 50.00  LDD0214 
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) LDTP04959 5.84  LDD0215 
Sialic acid synthase (NANS) LDTP12473 4.99  LDD0215 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 3.56  LDD0215 
Sorbitol dehydrogenase (SORD) LDTP05258 4.36  LDD0215 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 3.69  LDD0215 
STE20-like serine/threonine-protein kinase (SLK) LDTP11819 50.00  LDD0214 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 3.07  LDD0215 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 3.55  LDD0215 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 3.51  LDD0215 
Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 5.41  LDD0215 
Thioredoxin-like protein 1 (TXNL1) LDTP00758 5.57  LDD0215 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 3.89  LDD0215 
Thymidine kinase, cytosolic (TK1) LDTP02022 5.41  LDD0215 
Thymidylate synthase (TYMS) LDTP02055 4.31  LDD0215 
TRAF2 and NCK-interacting protein kinase (TNIK) LDTP13446 50.00  LDD0214 
Transaldolase (TALDO1) LDTP03847 3.09  LDD0215 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 3.80  LDD0215 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 3.48  LDD0215 
Transketolase (TKT) LDTP03487 3.56  LDD0215 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 3.76  LDD0215 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 2.61  LDD0215 
Triosephosphate isomerase (TPI1) LDTP04851 4.03  LDD0215 
Tripeptidyl-peptidase 2 (TPP2) LDTP03469 3.47  LDD0215 
Tryptophan--tRNA ligase, cytoplasmic (WARS1) LDTP03222 5.44  LDD0215 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 50.00  LDD0214 
Tubulin alpha-4A chain (TUBA4A) LDTP05075 3.61  LDD0215 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 4.13  LDD0215 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 3.35  LDD0215 
Tyrosine-protein kinase ABL1 (ABL1) LDTP01784 3.57  LDD0214 
Tyrosine-protein kinase BTK (BTK) LDTP05478 9.79  LDD0214 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 3.28  LDD0215 
Ubiquitin carboxyl-terminal hydrolase 15 (USP15) LDTP14051 4.90  LDD0215 
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) LDTP04074 2.34  LDD0215 
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) LDTP05070 5.74  LDD0215 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 3.76  LDD0215 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 3.59  LDD0215 
UDP-N-acetylhexosamine pyrophosphorylase (UAP1) LDTP06517 4.01  LDD0215 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 4.60  LDD0215 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 2.83  LDD0215 
Valine--tRNA ligase (VARS1) LDTP03366 3.07  LDD0215 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 5.73  LDD0215 
X-ray repair cross-complementing protein 5 (XRCC5) LDTP02642 3.69  LDD0215 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 3.05  LDD0215 
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⏷ Show the Full List of 265 Enzyme
56 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 3.46  LDD0215 
14-3-3 protein theta (YWHAQ) LDTP03385 3.73  LDD0215 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 3.21  LDD0215 
Ankyrin-1 (ANK1) LDTP02832 3.16  LDD0215 
Annexin A1 (ANXA1) LDTP02010 3.71  LDD0215 
Annexin A2 (ANXA2) LDTP02199 50.00  LDD0214 
AP-2 complex subunit alpha-1 (AP2A1) LDTP01673 5.18  LDD0215 
AP-2 complex subunit beta (AP2B1) LDTP05038 3.80  LDD0215 
AP-3 complex subunit delta-1 (AP3D1) LDTP00383 3.15  LDD0215 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 3.08  LDD0215 
ATP-binding cassette sub-family F member 1 (ABCF1) LDTP09149 3.68  LDD0215 
ATP-binding cassette sub-family F member 2 (ABCF2) LDTP18526 2.63  LDD0215 
Calnexin (CANX) LDTP03405 4.63  LDD0215 
Calreticulin (CALR) LDTP03402 5.59  LDD0215 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 4.34  LDD0215 
Clathrin heavy chain 1 (CLTC) LDTP05252 3.93  LDD0215 
EH domain-containing protein 1 (EHD1) LDTP11934 3.02  LDD0215 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 50.00  LDD0214 
Exportin-1 (XPO1) LDTP00501 4.17  LDD0215 
Exportin-2 (CSE1L) LDTP04662 4.21  LDD0215 
Exportin-5 (XPO5) LDTP12142 3.84  LDD0215 
Exportin-7 (XPO7) LDTP13335 4.10  LDD0215 
Extended synaptotagmin-1 (ESYT1) LDTP11161 2.70  LDD0215 
Filamin-A (FLNA) LDTP03107 3.20  LDD0215 
Filamin-B (FLNB) LDTP01197 4.21  LDD0215 
Filamin-C (FLNC) LDTP06103 2.98  LDD0215 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 3.53  LDD0215 
Hemoglobin subunit alpha (HBA1; HBA2) LDTP05084 2.79  LDD0215 
Importin subunit alpha-1 (KPNA2) LDTP04501 3.82  LDD0215 
Importin subunit beta-1 (KPNB1) LDTP06242 3.70  LDD0215 
Importin-4 (IPO4) LDTP09515 3.73  LDD0215 
Importin-5 (IPO5) LDTP00266 4.51  LDD0215 
Importin-7 (IPO7) LDTP01574 3.70  LDD0215 
Importin-9 (IPO9) LDTP10663 3.31  LDD0215 
Kinesin-1 heavy chain (KIF5B) LDTP03664 7.25  LDD0215 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) LDTP13698 3.46  LDD0215 
Nuclear pore complex protein Nup133 (NUP133) LDTP09579 2.91  LDD0215 
Nuclear pore complex protein Nup205 (NUP205) LDTP09825 3.65  LDD0215 
Nuclear pore complex protein Nup214 (NUP214) LDTP03777 4.16  LDD0215 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 3.62  LDD0215 
Nucleoporin NUP188 (NUP188) LDTP07064 3.63  LDD0215 
Nucleoprotein TPR (TPR) LDTP02612 2.49  LDD0215 
Protein transport protein Sec31A (SEC31A) LDTP01478 2.77  LDD0215 
Ran GTPase-activating protein 1 (RANGAP1) LDTP04082 2.81  LDD0215 
Serine/arginine repetitive matrix protein 1 (SRRM1) LDTP08637 5.93  LDD0215 
Signal recognition particle subunit SRP72 (SRP72) LDTP01402 3.28  LDD0215 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 3.89  LDD0215 
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 5.91  LDD0215 
T-complex protein 1 subunit delta (CCT4) LDTP04391 3.82  LDD0215 
Talin-1 (TLN1) LDTP14031 3.37  LDD0215 
THO complex subunit 2 (THOC2) LDTP09279 4.84  LDD0215 
Transferrin receptor protein 1 (TFRC) LDTP01969 3.50  LDD0215 
Transportin-1 (TNPO1) LDTP09949 2.74  LDD0215 
Transportin-3 (TNPO3) LDTP14133 4.40  LDD0215 
Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 4.95  LDD0215 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 3.66  LDD0215 
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⏷ Show the Full List of 56 Transporter and channel
13 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Cell growth-regulating nucleolar protein (LYAR) LDTP12761 3.37  LDD0215 
General transcription factor II-I (GTF2I) LDTP05101 3.31  LDD0215 
High mobility group protein B1 (HMGB1) LDTP02343 3.98  LDD0215 
High mobility group protein B2 (HMGB2) LDTP03363 4.41  LDD0215 
Hypermethylated in cancer 2 protein (HIC2) LDTP10453 2.70  LDD0215 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 2.35  LDD0215 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 4.08  LDD0215 
Replication initiator 1 (REPIN1) LDTP11322 3.51  LDD0215 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 2.45  LDD0214 
Signal transducer and activator of transcription 5A (STAT5A) LDTP03971 4.04  LDD0215 
Splicing factor, proline- and glutamine-rich (SFPQ) LDTP03212 2.88  LDD0215 
Y-box-binding protein 1 (YBX1) LDTP05065 3.84  LDD0215 
Zinc finger CCCH domain-containing protein 4 (ZC3H4) LDTP13718 3.54  LDD0215 
------------------------------------------------------------------------------------
⏷ Show the Full List of 13 Transcription factor
255 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein eta (YWHAH) LDTP05442 3.79  LDD0215 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 4.59  LDD0215 
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) LDTP06273 3.94  LDD0215 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 9.97  LDD0215 
Actin-related protein 2/3 complex subunit 1B (ARPC1B) LDTP00550 5.58  LDD0215 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 3.89  LDD0215 
Albumin (ALB) LDTP01963 4.71  LDD0215 
Alpha-actinin-4 (ACTN4) LDTP00843 3.53  LDD0215 
Ataxin-2-like protein (ATXN2L) LDTP09655 3.42  LDD0215 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 3.07  LDD0215 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 5.89  LDD0215 
CCR4-NOT transcription complex subunit 1 (CNOT1) LDTP00078 4.29  LDD0215 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 3.55  LDD0215 
CLIP-associating protein 1 (CLASP1) LDTP08062 2.70  LDD0215 
Clustered mitochondria protein homolog (CLUH) LDTP14486 4.33  LDD0215 
Coatomer subunit alpha (COPA) LDTP04571 3.22  LDD0215 
Coatomer subunit beta (COPB1) LDTP04570 3.89  LDD0215 
Coatomer subunit delta (ARCN1) LDTP04181 2.33  LDD0215 
Coatomer subunit gamma-1 (COPG1) LDTP14216 2.11  LDD0215 
Cofilin-1 (CFL1) LDTP03244 5.24  LDD0215 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 3.55  LDD0215 
Condensin complex subunit 1 (NCAPD2) LDTP06281 4.52  LDD0215 
Constitutive coactivator of PPAR-gamma-like protein 1 (FAM120A) LDTP12883 3.68  LDD0215 
Coronin-1C (CORO1C) LDTP13580 3.14  LDD0215 
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) LDTP13269 2.78  LDD0215 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 3.50  LDD0215 
Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) LDTP05855 4.47  LDD0215 
Cytoskeleton-associated protein 5 (CKAP5) LDTP06021 2.33  LDD0215 
DNA damage-binding protein 1 (DDB1) LDTP06543 4.01  LDD0215 
DNA mismatch repair protein Msh6 (MSH6) LDTP04518 3.27  LDD0215 
DnaJ homolog subfamily A member 1 (DNAJA1) LDTP03606 3.24  LDD0215 
ELAV-like protein 1 (ELAVL1) LDTP06450 3.85  LDD0215 
Elongation factor 1-delta (EEF1D) LDTP03499 3.31  LDD0215 
Elongation factor 1-gamma (EEF1G) LDTP03367 3.94  LDD0215 
Elongator complex protein 1 (ELP1) LDTP01511 4.81  LDD0215 
Endoplasmin (HSP90B1) LDTP02734 3.35  LDD0215 
Enhancer of mRNA-decapping protein 4 (EDC4) LDTP07521 4.16  LDD0215 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 3.36  LDD0215 
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 3.64  LDD0215 
Eukaryotic translation initiation factor 2A (EIF2A) LDTP11436 5.94  LDD0215 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 3.69  LDD0215 
Eukaryotic translation initiation factor 3 subunit B (EIF3B) LDTP04718 3.77  LDD0215 
Eukaryotic translation initiation factor 3 subunit D (EIF3D) LDTP00619 2.66  LDD0215 
Eukaryotic translation initiation factor 3 subunit E (EIF3E) LDTP04853 3.01  LDD0215 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 3.36  LDD0215 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 3.34  LDD0215 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 5.96  LDD0215 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 3.33  LDD0215 
Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) LDTP05421 3.04  LDD0215 
Eukaryotic translation initiation factor 4 gamma 2 (EIF4G2) LDTP05098 3.54  LDD0215 
Ezrin (EZR) LDTP02779 2.78  LDD0215 
F-actin-capping protein subunit beta (CAPZB) LDTP04127 50.00  LDD0214 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 2.89  LDD0215 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 4.36  LDD0215 
Fascin (FSCN1) LDTP06598 3.65  LDD0215 
Fermitin family homolog 3 (FERMT3) LDTP08263 3.07  LDD0215 
Four and a half LIM domains protein 3 (FHL3) LDTP05962 2.62  LDD0215 
Galectin-1 (LGALS1) LDTP02341 8.11  LDD0215 
Gem-associated protein 5 (GEMIN5) LDTP09504 3.06  LDD0215 
General vesicular transport factor p115 (USO1) LDTP01048 3.21  LDD0215 
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) LDTP06255 2.72  LDD0215 
Heat shock 70 kDa protein 1B (HSPA1B) LDTP02435 4.46  LDD0215 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 3.36  LDD0215 
Heat shock protein 105 kDa (HSPH1) LDTP09811 3.73  LDD0215 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 3.59  LDD0215 
Heat shock protein beta-1 (HSPB1) LDTP02053 3.27  LDD0215 
Hemogen (HEMGN) LDTP15907 4.94  LDD0215 
Hemoglobin subunit epsilon (HBE1) LDTP01922 3.87  LDD0215 
Hemoglobin subunit zeta (HBZ) LDTP01920 3.41  LDD0215 
Hepatoma-derived growth factor (HDGF) LDTP04483 3.93  LDD0215 
Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0) LDTP05768 3.28  LDD0215 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 2.86  LDD0215 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 2.94  LDD0215 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 4.71  LDD0215 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 6.22  LDD0215 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 3.33  LDD0215 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 3.86  LDD0215 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 4.47  LDD0215 
Heterogeneous nuclear ribonucleoprotein L (HNRNPL) LDTP02750 3.87  LDD0215 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 4.33  LDD0215 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 3.65  LDD0215 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 3.66  LDD0215 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 2.66  LDD0215 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 3.07  LDD0215 
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) LDTP02227 4.52  LDD0215 
Histone H1.5 (H1-5) LDTP02843 4.24  LDD0215 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 5.34  LDD0215 
Histone-binding protein RBBP4 (RBBP4) LDTP05590 6.22  LDD0215 
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) LDTP12904 4.06  LDD0215 
Interleukin enhancer-binding factor 3 (ILF3) LDTP05689 3.55  LDD0215 
Jupiter microtubule associated homolog 2 (JPT2) LDTP12077 4.25  LDD0215 
Keratin, type I cytoskeletal 10 (KRT10) LDTP02674 3.70  LDD0215 
Keratin, type I cytoskeletal 9 (KRT9) LDTP03755 3.10  LDD0215 
Keratin, type II cytoskeletal 2 epidermal (KRT2) LDTP03792 3.05  LDD0215 
Keratin, type II cytoskeletal 8 (KRT8) LDTP02125 3.74  LDD0215 
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) LDTP05525 3.07  LDD0215 
Lamin-B1 (LMNB1) LDTP03065 3.28  LDD0215 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 5.07  LDD0215 
Large proline-rich protein BAG6 (BAG6) LDTP04094 2.63  LDD0215 
Large ribosomal subunit protein eL13 (RPL13) LDTP03354 3.15  LDD0215 
Large ribosomal subunit protein eL14 (RPL14) LDTP04389 3.08  LDD0215 
Large ribosomal subunit protein eL15 (RPL15) LDTP04919 2.76  LDD0215 
Large ribosomal subunit protein eL18 (RPL18) LDTP05509 3.02  LDD0215 
Large ribosomal subunit protein eL19 (RPL19) LDTP05196 3.03  LDD0215 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 3.57  LDD0215 
Large ribosomal subunit protein eL21 (RPL21) LDTP04107 2.48  LDD0215 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 3.86  LDD0215 
Large ribosomal subunit protein eL27 (RPL27) LDTP04922 2.64  LDD0215 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 3.88  LDD0215 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 3.80  LDD0215 
Large ribosomal subunit protein eL31 (RPL31) LDTP05023 3.69  LDD0215 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 4.15  LDD0215 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 3.40  LDD0215 
Large ribosomal subunit protein eL36 (RPL36) LDTP14012 4.59  LDD0215 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 4.00  LDD0215 
Large ribosomal subunit protein eL8 (RPL7A) LDTP04990 3.28  LDD0215 
Large ribosomal subunit protein uL1 (RPL10A) LDTP05024 4.53  LDD0215 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 2.95  LDD0215 
Large ribosomal subunit protein uL13 (RPL13A) LDTP03899 2.91  LDD0215 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 3.51  LDD0215 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 3.49  LDD0215 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 3.82  LDD0215 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 3.49  LDD0215 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 3.88  LDD0215 
Large ribosomal subunit protein uL22 (RPL17) LDTP02961 2.80  LDD0215 
Large ribosomal subunit protein uL23 (RPL23A) LDTP05001 2.58  LDD0215 
Large ribosomal subunit protein uL24 (RPL26) LDTP04914 3.21  LDD0215 
Large ribosomal subunit protein uL29 (RPL35) LDTP03999 5.73  LDD0215 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 3.94  LDD0215 
Large ribosomal subunit protein uL30 (RPL7) LDTP02944 3.42  LDD0215 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 3.57  LDD0215 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 3.92  LDD0215 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 3.21  LDD0215 
Lipopolysaccharide-responsive and beige-like anchor protein (LRBA) LDTP04385 50.00  LDD0214 
Lupus La protein (SSB) LDTP02116 3.41  LDD0215 
Matrin-3 (MATR3) LDTP04027 3.37  LDD0215 
Microtubule-associated protein 4 (MAP4) LDTP03404 3.11  LDD0215 
Midasin (MDN1) LDTP12619 3.95  LDD0215 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 3.67  LDD0215 
Moesin (MSN) LDTP03346 2.83  LDD0215 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 3.92  LDD0215 
Nuclear migration protein nudC (NUDC) LDTP13817 3.75  LDD0215 
Nucleolin (NCL) LDTP02990 4.10  LDD0215 
Nucleophosmin (NPM1) LDTP02164 3.84  LDD0215 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 2.04  LDD0214 
Paxillin (PXN) LDTP04226 3.73  LDD0215 
PDZ and LIM domain protein 5 (PDLIM5) LDTP10383 3.79  LDD0215 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 6.13  LDD0215 
Phosphatidylinositol-binding clathrin assembly protein (PICALM) LDTP05895 3.34  LDD0215 
Plastin-2 (LCP1) LDTP02691 3.23  LDD0215 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 4.73  LDD0215 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 4.20  LDD0215 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 2.88  LDD0215 
Pre-mRNA-processing factor 40 homolog A (PRPF40A) LDTP01208 6.96  LDD0215 
Pre-mRNA-processing factor 6 (PRPF6) LDTP01456 2.54  LDD0215 
Pre-mRNA-processing-splicing factor 8 (PRPF8) LDTP07526 3.19  LDD0215 
Prelamin-A/C (LMNA) LDTP01932 4.07  LDD0215 
Profilin-1 (PFN1) LDTP02218 3.23  LDD0215 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 3.45  LDD0215 
Proliferating cell nuclear antigen (PCNA) LDTP02596 3.92  LDD0215 
Proteasome activator complex subunit 4 (PSME4) LDTP06250 5.72  LDD0215 
Proteasome adapter and scaffold protein ECM29 (ECPAS) LDTP07255 4.18  LDD0215 
Protein diaphanous homolog 1 (DIAPH1) LDTP01011 4.30  LDD0215 
Protein LYRIC (MTDH) LDTP08224 3.99  LDD0215 
Protein PRRC2A (PRRC2A) LDTP04199 2.48  LDD0215 
Protein RCC2 (RCC2) LDTP13020 4.52  LDD0215 
Protein transport protein Sec23B (SEC23B) LDTP06391 3.53  LDD0215 
Protein unc-13 homolog D (UNC13D) LDTP07888 4.64  LDD0215 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 4.28  LDD0215 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 4.20  LDD0215 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 3.79  LDD0215 
Ras GTPase-activating protein-binding protein 2 (G3BP2) LDTP13647 4.51  LDD0215 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 2.95  LDD0215 
Reticulon-4 (RTN4) LDTP12412 3.71  LDD0215 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 4.17  LDD0215 
Ribonuclease inhibitor (RNH1) LDTP02656 5.08  LDD0215 
Ribonucleoprotein PTB-binding 1 (RAVER1) LDTP15356 3.20  LDD0215 
Ribosomal L1 domain-containing protein 1 (RSL1D1) LDTP01379 3.40  LDD0215 
Ribosome biogenesis protein BRX1 homolog (BRIX1) LDTP15609 4.75  LDD0215 
Ribosome-binding protein 1 (RRBP1) LDTP13044 3.10  LDD0215 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 3.66  LDD0215 
RNA-binding protein 14 (RBM14) LDTP10684 2.90  LDD0215 
RNA-binding protein 4 (RBM4) LDTP11324 5.92  LDD0215 
RNA-binding protein RO60 (RO60) LDTP02480 2.82  LDD0215 
Scaffold attachment factor B2 (SAFB2) LDTP06054 4.08  LDD0215 
Serine/arginine repetitive matrix protein 2 (SRRM2) LDTP13746 2.93  LDD0215 
Serpin H1 (SERPINH1) LDTP04363 3.18  LDD0215 
SERPINE1 mRNA-binding protein 1 (SERBP1) LDTP09081 50.00  LDD0214 
Serrate RNA effector molecule homolog (SRRT) LDTP11398 4.54  LDD0215 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 3.36  LDD0215 
Sister chromatid cohesion protein PDS5 homolog B (PDS5B) LDTP12605 3.44  LDD0215 
Small nuclear ribonucleoprotein Sm D2 (SNRPD2) LDTP04982 3.80  LDD0215 
Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB) LDTP02741 4.69  LDD0215 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 4.66  LDD0215 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 3.33  LDD0215 
Small ribosomal subunit protein eS19 (RPS19) LDTP03864 2.75  LDD0215 
Small ribosomal subunit protein eS25 (RPS25) LDTP05013 3.35  LDD0215 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 3.83  LDD0215 
Small ribosomal subunit protein eS6 (RPS6) LDTP05002 3.72  LDD0215 
Small ribosomal subunit protein eS7 (RPS7) LDTP04958 3.60  LDD0215 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 3.32  LDD0215 
Small ribosomal subunit protein uS10 (RPS20) LDTP04880 4.24  LDD0215 
Small ribosomal subunit protein uS11 (RPS14) LDTP04970 4.37  LDD0215 
Small ribosomal subunit protein uS13 (RPS18) LDTP04972 3.74  LDD0215 
Small ribosomal subunit protein uS14 (RPS29) LDTP04973 3.70  LDD0215 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 4.33  LDD0215 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 2.77  LDD0215 
Small ribosomal subunit protein uS4 (RPS9) LDTP04109 3.43  LDD0215 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 3.41  LDD0215 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 4.36  LDD0215 
Small ribosomal subunit protein uS8 (RPS15A) LDTP04965 3.34  LDD0215 
Small ribosomal subunit protein uS9 (RPS16) LDTP04966 4.43  LDD0215 
Spectrin alpha chain, erythrocytic 1 (SPTA1) LDTP01933 2.67  LDD0215 
Spectrin beta chain, erythrocytic (SPTB) LDTP02561 3.69  LDD0215 
Splicing factor 1 (SF1) LDTP06429 2.79  LDD0215 
Splicing factor 3A subunit 1 (SF3A1) LDTP06393 3.27  LDD0215 
Splicing factor 3B subunit 1 (SF3B1) LDTP01251 3.70  LDD0215 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 4.22  LDD0215 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 6.25  LDD0215 
Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) LDTP06280 4.68  LDD0215 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 3.80  LDD0215 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 3.74  LDD0215 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 3.76  LDD0215 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 4.32  LDD0215 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 2.26  LDD0215 
Structural maintenance of chromosomes protein 3 (SMC3) LDTP13760 2.96  LDD0215 
Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 3.36  LDD0215 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 3.46  LDD0215 
T-complex protein 1 subunit beta (CCT2) LDTP05113 4.47  LDD0215 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 4.21  LDD0215 
T-complex protein 1 subunit eta (CCT7) LDTP10990 3.28  LDD0215 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 4.14  LDD0215 
T-complex protein 1 subunit theta (CCT8) LDTP04390 3.54  LDD0215 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 3.43  LDD0215 
TAR DNA-binding protein 43 (TARDBP) LDTP05767 4.36  LDD0215 
Telomere-associated protein RIF1 (RIF1) LDTP07205 2.42  LDD0215 
Thyroid hormone receptor-associated protein 3 (THRAP3) LDTP13919 3.28  LDD0215 
Thyroid receptor-interacting protein 6 (TRIP6) LDTP06439 5.14  LDD0215 
Transcription elongation factor SPT5 (SUPT5H) LDTP00236 2.87  LDD0215 
Transgelin-2 (TAGLN2) LDTP03846 4.45  LDD0215 
Treacle protein (TCOF1) LDTP05867 8.35  LDD0215 
Tubulin beta chain (TUBB) LDTP02205 3.96  LDD0215 
Tubulin beta-6 chain (TUBB6) LDTP11233 4.20  LDD0215 
Tubulin-specific chaperone A (TBCA) LDTP01184 3.89  LDD0215 
U1 small nuclear ribonucleoprotein 70 kDa (SNRNP70) LDTP02292 2.59  LDD0215 
U2 snRNP-associated SURP motif-containing protein (U2SURP) LDTP00517 4.49  LDD0215 
Ubiquitin-associated protein 2 (UBAP2) LDTP07132 2.15  LDD0215 
Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) LDTP05033 6.42  LDD0215 
Vimentin (VIM) LDTP02297 3.44  LDD0215 
Vinculin (VCL) LDTP02946 3.42  LDD0215 
WD repeat-containing protein 1 (WDR1) LDTP01118 2.42  LDD0215 
YTH domain-containing family protein 2 (YTHDF2) LDTP14105 3.67  LDD0215 
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) LDTP08018 3.51  LDD0215 
Zinc finger Ran-binding domain-containing protein 2 (ZRANB2) LDTP01530 3.97  LDD0215 
Zinc finger RNA-binding protein (ZFR) LDTP15762 3.62  LDD0215 
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Full Information of The Labelling Profiles of This Probe

Quantification: Probe vs DMSO
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
0.2 uM
Quantitative Method
LFQ
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Peripheral blood
Disease Model
Chronic myeloid leukemia [ICD-11:2A20]
Model Name
Human chronic myeloid leukemia cell lysate (K562)
Interaction Atlas ID
 LDD0214 
Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
2 uM
Quantitative Method
LFQ
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Peripheral blood
Disease Model
Chronic myeloid leukemia [ICD-11:2A20]
Model Name
Human chronic myeloid leukemia cell lysate (K562)
Interaction Atlas ID
 LDD0215 
Download The Altas

References

1 2-Ethynylbenzaldehyde-Based, Lysine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Nonkinases. J Am Chem Soc. 2023 Feb 12. doi: 10.1021/jacs.2c11595. Online ahead of print.
Mass spectrometry data entry: PXD037665