Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0510
Competitor Name
3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile
Synonyms
3-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 334.4
Lipid-water partition coefficient (xlogp) 2.7
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C21H22N2O2
IUPAC Name
3-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]-3-oxopropanenitrile
Canonical SMILES
C1CN(CCC1C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C(=O)CC#N
InChI
InChI=1S/C21H22N2O2/c22-14-11-20(24)23-15-12-19(13-16-23)21(25,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-10,19,25H,11-13,15-16H2
InChIKey
OITIBQLJKFJUSW-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
BTD
 Probe Info  		5 mM Human breast adenocarcinoma cell lysate (MDA-MB-231) [1]

Target(s) List of this Competitor

309 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
2',5'-phosphodiesterase 12 (PDE12) LDTP07447 0.97  LDD2103 
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1) LDTP06612 0.91  LDD2103 
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (GCAT) LDTP01268 1.48  LDD2103 
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) LDTP10869 0.98  LDD2103 
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) LDTP00224 0.88  LDD2103 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 1.68; 1.04  LDD2103 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 1.07  LDD2103 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 1.24; 1.01  LDD2103 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 1.11  LDD2103 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 1.03; 1.08  LDD2103 
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) LDTP02329 1.17  LDD2103 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 0.86  LDD2103 
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) LDTP04232 1.01; 1.03  LDD2103 
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) LDTP06655 1.03  LDD2103 
6-phosphogluconolactonase (PGLS) LDTP14535 1.54  LDD2103 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.92  LDD2103 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 1.30  LDD2103 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 0.97; 0.98  LDD2103 
Aconitate hydratase, mitochondrial (ACO2) LDTP10982 1.15; 1.14  LDD2103 
Acyl-coenzyme A thioesterase 9, mitochondrial (ACOT9) LDTP16274 0.77  LDD2103 
Acyl-protein thioesterase 2 (LYPLA2) LDTP01573 1.07  LDD2103 
Acylphosphatase-2 (ACYP2) LDTP14633 0.59  LDD2103 
Adenosine 5'-monophosphoramidase HINT1 (HINT1) LDTP04306 1.71  LDD2103 
Adenosylhomocysteinase (AHCY) LDTP03242 0.83; 0.98  LDD2103 
Adenylosuccinate lyase (ADSL) LDTP03551 1.95  LDD2103 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 1.15  LDD2103 
Aldehyde dehydrogenase 1A1 (ALDH1A1) LDTP01767 1.03; 0.66  LDD2103 
Aldehyde oxidase (AOX1) LDTP05483 0.98  LDD2103 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 1.31; 1.04; 1.78  LDD2103 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 1.12  LDD2103 
Alpha-enolase (ENO1) LDTP02159 1.96; 1.02  LDD2103 
Aminoacylase-1 (ACY1) LDTP05395 1.09  LDD2103 
Anaphase-promoting complex subunit 7 (ANAPC7) LDTP13409 0.93  LDD2103 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.99  LDD2103 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 0.98  LDD2103 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 0.74; 1.35  LDD2103 
ATP-citrate synthase (ACLY) LDTP04561 1.10  LDD2103 
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) LDTP05314 1.09  LDD2103 
ATP-dependent RNA helicase A (DHX9) LDTP05550 1.25; 1.47  LDD2103 
ATP-dependent RNA helicase DDX24 (DDX24) LDTP15942 0.85; 0.79  LDD2103 
ATP-dependent RNA helicase DDX39A (DDX39A) LDTP00192 0.97; 1.09  LDD2103 
ATP-dependent RNA helicase DDX3X (DDX3X) LDTP00314 0.96  LDD2103 
ATP-dependent RNA helicase DHX30 (DHX30) LDTP07946 0.93  LDD2103 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 0.96  LDD2103 
Beta-ureidopropionase (UPB1) LDTP13146 2.10  LDD2103 
Betaine--homocysteine S-methyltransferase 1 (BHMT) LDTP09978 1.35; 0.99  LDD2103 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 1.01; 0.87; 1.24  LDD2103 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 1.04  LDD2103 
Calcyclin-binding protein (CACYBP) LDTP12163 0.65  LDD2103 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 1.08; 1.07  LDD2103 
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (CMTR1) LDTP08773 0.99  LDD2103 
Carboxypeptidase D (CPD) LDTP01372 0.74  LDD2103 
Casein kinase II subunit alpha' (CSNK2A2) LDTP03011 1.00  LDD2103 
Catalase (CAT) LDTP02001 1.90; 1.06  LDD2103 
CCA tRNA nucleotidyltransferase 1, mitochondrial (TRNT1) LDTP10716 0.89  LDD2103 
Cell division control protein 42 homolog (CDC42) LDTP04886 0.99  LDD2103 
Choline-phosphate cytidylyltransferase A (PCYT1A) LDTP04261 1.44  LDD2103 
Chromodomain-helicase-DNA-binding protein 4 (CHD4) LDTP06219 1.18  LDD2103 
Citrate synthase, mitochondrial (CS) LDTP01205 0.93; 1.28  LDD2103 
COP9 signalosome complex subunit 5 (COPS5) LDTP09925 0.83  LDD2103 
CTP synthase 1 (CTPS1) LDTP02922 0.93; 0.96  LDD2103 
Cullin-2 (CUL2) LDTP05947 1.01  LDD2103 
Cullin-associated NEDD8-dissociated protein 1 (CAND1) LDTP08296 0.98  LDD2103 
Cyclin-dependent kinase 11B (CDK11B) LDTP03098 1.80  LDD2103 
Cyclin-dependent kinase 18 (CDK18) LDTP05507 1.30  LDD2103 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 1.07  LDD2103 
Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH) LDTP02229 0.65; 0.66; 0.52  LDD2103 
Cytochrome c1, heme protein, mitochondrial (CYC1) LDTP02283 0.94  LDD2103 
Cytoplasmic aconitate hydratase (ACO1) LDTP03110 0.95  LDD2103 
Cytosol aminopeptidase (LAP3) LDTP03455 1.26  LDD2103 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 0.76  LDD2103 
Cytosolic non-specific dipeptidase (CNDP2) LDTP10514 0.93  LDD2103 
DCN1-like protein 1 (DCUN1D1) LDTP10349 0.93  LDD2103 
DDB1- and CUL4-associated factor 1 (DCAF1) LDTP14038 1.03  LDD2103 
Delta(24)-sterol reductase (DHCR24) LDTP06375 1.22  LDD2103 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 0.99  LDD2103 
Diphosphomevalonate decarboxylase (MVD) LDTP04567 0.95  LDD2103 
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM15) LDTP05874 0.98  LDD2103 
DNA (cytosine-5)-methyltransferase 1 (DNMT1) LDTP03350 0.98; 0.74  LDD2103 
DNA excision repair protein ERCC-6-like (ERCC6L) LDTP06713 1.28  LDD2103 
DNA polymerase delta catalytic subunit (POLD1) LDTP03437 0.95  LDD2103 
DNA polymerase delta subunit 2 (POLD2) LDTP04223 0.97  LDD2103 
DNA repair protein RAD50 (RAD50) LDTP09912 0.89  LDD2103 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 1.19; 1.05; 0.97  LDD2103 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 0.81  LDD2103 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 1.49  LDD2103 
DNA topoisomerase 1 (TOP1) LDTP02567 0.92  LDD2103 
DNA topoisomerase 2-alpha (TOP2A) LDTP02568 0.92; 1.16  LDD2103 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 1.36; 1.00; 0.76 ...  LDD2103 
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LDTP13087 0.91  LDD2103 
Dolichyl-phosphate beta-glucosyltransferase (ALG5) LDTP14214 0.94  LDD2103 
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) LDTP04103 1.14  LDD2103 
Dynamin-2 (DNM2) LDTP04374 0.80  LDD2103 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 0.85  LDD2103 
E3 SUMO-protein ligase RanBP2 (RANBP2) LDTP04310 1.67; 1.18; 1.04 ...  LDD2103 
E3 ubiquitin-protein ligase BRE1A (RNF20) LDTP07218 0.89  LDD2103 
E3 ubiquitin-protein ligase HUWE1 (HUWE1) LDTP08135 0.60; 1.00; 0.72  LDD2103 
E3 ubiquitin-protein ligase RBX1 (RBX1) LDTP05019 1.06  LDD2103 
E3 ubiquitin-protein ligase RNF213 (RNF213) LDTP07283 0.86  LDD2103 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 1.03  LDD2103 
E3 ubiquitin-protein ligase UBR5 (UBR5) LDTP01495 1.01  LDD2103 
E3 ubiquitin-protein ligase UHRF1 (UHRF1) LDTP10845 0.98  LDD2103 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 0.96  LDD2103 
Elongation factor 2 (EEF2) LDTP02672 1.23; 1.39; 1.08  LDD2103 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 0.81  LDD2103 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 1.16  LDD2103 
Ephrin type-A receptor 2 (EPHA2) LDTP03474 1.04; 0.90  LDD2103 
ERO1-like protein alpha (ERO1A) LDTP10386 0.90; 1.24  LDD2103 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 1.30; 0.77  LDD2103 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 1.36; 0.93  LDD2103 
Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) LDTP03915 1.18  LDD2103 
Eukaryotic translation initiation factor 5B (EIF5B) LDTP01063 1.11  LDD2103 
Exosome complex component 10 (EXOSC10) LDTP05312 1.02  LDD2103 
Exosome complex component RRP45 (EXOSC9) LDTP05482 1.00  LDD2103 
Exosome complex component RRP46 (EXOSC5) LDTP12433 1.23  LDD2103 
F-box only protein 11 (FBXO11) LDTP08361 1.34  LDD2103 
FAST kinase domain-containing protein 2, mitochondrial (FASTKD2) LDTP12862 1.47  LDD2103 
Fatty acid synthase (FASN) LDTP04243 1.49; 1.07; 1.18  LDD2103 
Gamma-glutamylcyclotransferase (GGCT) LDTP01164 3.45  LDD2103 
GDP-fucose protein O-fucosyltransferase 1 (POFUT1) LDTP11905 0.71  LDD2103 
Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1) LDTP10264 0.83  LDD2103 
Glucose-6-phosphate isomerase (GPI) LDTP02162 1.10  LDD2103 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 1.11; 1.28  LDD2103 
Glutathione S-transferase P (GSTP1) LDTP02333 1.08  LDD2103 
Glutathione synthetase (GSS) LDTP04200 1.73  LDD2103 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 1.81; 1.39; 1.51  LDD2103 
Glycine--tRNA ligase (GARS1) LDTP03946 1.28; 1.52  LDD2103 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 1.13  LDD2103 
Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) LDTP03537 1.03  LDD2103 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 0.92; 0.96; 0.96  LDD2103 
GPI-anchor transamidase (PIGK) LDTP09835 0.96  LDD2103 
GTP-binding nuclear protein Ran (RAN) LDTP05007 1.10  LDD2103 
Guanine nucleotide-binding protein-like 3 (GNL3) LDTP11297 0.81; 0.97  LDD2103 
H/ACA ribonucleoprotein complex subunit DKC1 (DKC1) LDTP01061 0.96  LDD2103 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 0.94; 1.32  LDD2103 
Heme oxygenase 2 (HMOX2) LDTP03540 1.07; 1.09  LDD2103 
Hexokinase-1 (HK1) LDTP02991 1.89; 0.80  LDD2103 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 1.02  LDD2103 
Histone deacetylase 1 (HDAC1) LDTP05918 1.04  LDD2103 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 0.99  LDD2103 
Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) LDTP07762 1.21; 0.84  LDD2103 
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) LDTP01782 1.03  LDD2103 
Immunity-related GTPase family Q protein (IRGQ) LDTP19838 1.11  LDD2103 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 1.05  LDD2103 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 1.00; 0.91  LDD2103 
Integrin-linked protein kinase (ILK) LDTP05859 0.97  LDD2103 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 1.02  LDD2103 
Isoleucine--tRNA ligase, mitochondrial (IARS2) LDTP12588 0.79  LDD2103 
Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) LDTP06006 0.76  LDD2103 
Ketosamine-3-kinase (FN3KRP) LDTP16025 0.73  LDD2103 
Kinesin-like protein KIF23 (KIF23) LDTP05344 1.10  LDD2103 
Kinesin-like protein KIF2A (KIF2A) LDTP00188 0.81  LDD2103 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 1.41  LDD2103 
Large ribosomal subunit protein mL44 (MRPL44) LDTP12098 1.04  LDD2103 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 1.14  LDD2103 
Lon protease homolog, mitochondrial (LONP1) LDTP03817 0.63; 1.40  LDD2103 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 0.88  LDD2103 
Lysine-specific demethylase 3B (KDM3B) LDTP07982 1.13  LDD2103 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 1.06  LDD2103 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 0.97  LDD2103 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 1.30  LDD2103 
Microsomal glutathione S-transferase 1 (MGST1) LDTP02506 0.89  LDD2103 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 1.09  LDD2103 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 0.96; 1.09  LDD2103 
Multifunctional protein CAD (CAD) LDTP03401 1.08; 1.00  LDD2103 
Myosin-10 (MYH10) LDTP03765 0.81  LDD2103 
Myosin-9 (MYH9) LDTP03764 0.87; 1.06  LDD2103 
N-acylneuraminate cytidylyltransferase (CMAS) LDTP09228 0.98  LDD2103 
N-alpha-acetyltransferase 10 (NAA10) LDTP03938 1.00  LDD2103 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 1.00; 0.97; 0.85  LDD2103 
N-terminal kinase-like protein (SCYL1) LDTP10503 1.08  LDD2103 
NAD kinase 2, mitochondrial (NADK2) LDTP06839 1.10  LDD2103 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 1.07  LDD2103 
NADH dehydrogenase 1 alpha subcomplex subunit 5 (NDUFA5) LDTP06614 1.06  LDD2103 
NADH dehydrogenase iron-sulfur protein 6, mitochondrial (NDUFS6) LDTP14493 0.87  LDD2103 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 1.19  LDD2103 
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT) LDTP06346 1.17  LDD2103 
Nitric oxide synthase-interacting protein (NOSIP) LDTP13940 0.72  LDD2103 
Nuclear pore complex protein Nup98-Nup96 (NUP98) LDTP04547 0.92  LDD2103 
Obg-like ATPase 1 (OLA1) LDTP12610 0.98; 1.22  LDD2103 
Ornithine aminotransferase, mitochondrial (OAT) LDTP02021 0.72  LDD2103 
Parkinson disease protein 7 (PARK7) LDTP10878 1.03  LDD2103 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 1.20; 1.16  LDD2103 
Peptidyl-prolyl cis-trans isomerase B (PPIB) LDTP03216 0.89  LDD2103 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 1.09  LDD2103 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 1.56  LDD2103 
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) LDTP06104 1.60; 0.93  LDD2103 
Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2) LDTP13989 1.19  LDD2103 
Peroxiredoxin-1 (PRDX1) LDTP05503 0.71  LDD2103 
Peroxiredoxin-6 (PRDX6) LDTP03510 1.29  LDD2103 
Peroxisomal multifunctional enzyme type 2 (HSD17B4) LDTP04440 0.98  LDD2103 
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (INPPL1) LDTP00617 0.90  LDD2103 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 1.11  LDD2103 
Phosphoglucomutase-1 (PGM1) LDTP03818 1.06  LDD2103 
Phospholipase A-2-activating protein (PLAA) LDTP13814 1.46  LDD2103 
Phosphopentomutase (PGM2) LDTP10326 1.04  LDD2103 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 0.68  LDD2103 
Platelet-activating factor acetylhydrolase IB subunit alpha2 (PAFAH1B2) LDTP05078 0.92  LDD2103 
Poly [ADP-ribose] polymerase 1 (PARP1) LDTP02375 0.88; 1.08  LDD2103 
Poly(A) polymerase alpha (PAPOLA) LDTP04394 1.02  LDD2103 
Poly(A) RNA polymerase, mitochondrial (MTPAP) LDTP12696 0.80  LDD2103 
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (DHX16) LDTP00915 0.86  LDD2103 
Presequence protease, mitochondrial (PITRM1) LDTP07003 1.04  LDD2103 
Probable ATP-dependent RNA helicase DDX17 (DDX17) LDTP09899 0.79; 0.82  LDD2103 
Probable ATP-dependent RNA helicase DDX47 (DDX47) LDTP11730 0.90  LDD2103 
Probable ATP-dependent RNA helicase DDX5 (DDX5) LDTP02924 0.83; 0.79  LDD2103 
Probable ATP-dependent RNA helicase DDX52 (DDX52) LDTP13904 1.08  LDD2103 
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein (ASMTL) LDTP01647 1.35  LDD2103 
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG8) LDTP11290 0.94  LDD2103 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2) LDTP00285 1.03  LDD2103 
Prolyl 3-hydroxylase 2 (P3H2) LDTP08504 1.12  LDD2103 
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) LDTP02096 0.78  LDD2103 
Proteasome subunit alpha type-4 (PSMA4) LDTP03333 0.70  LDD2103 
Proteasome subunit alpha type-5 (PSMA5) LDTP03413 1.01  LDD2103 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 1.04  LDD2103 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 1.19  LDD2103 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 1.57  LDD2103 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 1.04  LDD2103 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 1.17  LDD2103 
Protein disulfide-isomerase (P4HB) LDTP02188 1.01; 1.18  LDD2103 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.98  LDD2103 
Protein PML (PML) LDTP03496 1.47; 0.97  LDD2103 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 0.83; 0.92; 1.08 ...  LDD2103 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 0.96  LDD2103 
Pterin-4-alpha-carbinolamine dehydratase (PCBD1) LDTP04925 0.59  LDD2103 
Putative methyltransferase C9orf114 (SPOUT1) LDTP07101 0.92  LDD2103 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 1.39  LDD2103 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 0.89  LDD2103 
Pyruvate kinase PKM (PKM) LDTP02733 1.31; 1.58  LDD2103 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 1.43  LDD2103 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 1.04; 1.35  LDD2103 
Ras-related C3 botulinum toxin substrate 2 (RAC2) LDTP02768 1.39  LDD2103 
Ras-related protein Rab-10 (RAB10) LDTP04895 0.95  LDD2103 
Ras-related protein Rab-13 (RAB13) LDTP04401 1.06  LDD2103 
Ras-related protein Rab-14 (RAB14) LDTP04901 1.13  LDD2103 
Ras-related protein Rab-1A (RAB1A) LDTP05006 1.02  LDD2103 
Ras-related protein Rab-34 (RAB34) LDTP11535 0.98  LDD2103 
Ras-related protein Rab-8A (RAB8A) LDTP04888 0.99  LDD2103 
Replication factor C subunit 3 (RFC3) LDTP03911 1.07  LDD2103 
Replication factor C subunit 5 (RFC5) LDTP03910 1.03  LDD2103 
Rho-associated protein kinase 2 (ROCK2) LDTP01127 0.87  LDD2103 
Ribonucleases P/MRP protein subunit POP1 (POP1) LDTP10903 0.83  LDD2103 
Ribosomal oxygenase 2 (RIOX2) LDTP08451 0.66  LDD2103 
RNA cytidine acetyltransferase (NAT10) LDTP11690 1.20; 0.93  LDD2103 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 1.03; 0.94; 0.82  LDD2103 
RNA-binding protein PNO1 (PNO1) LDTP12542 1.07  LDD2103 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 0.81  LDD2103 
rRNA 2'-O-methyltransferase fibrillarin (FBL) LDTP03155 0.94  LDD2103 
S-phase kinase-associated protein 1 (SKP1) LDTP05052 0.57; 1.21  LDD2103 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 0.95; 0.85; 1.08 ...  LDD2103 
Secernin-1 (SCRN1) LDTP05640 1.00  LDD2103 
Sepiapterin reductase (SPR) LDTP03730 1.02  LDD2103 
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) LDTP05183 0.74  LDD2103 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 0.89; 1.26; 1.20 ...  LDD2103 
Serine--tRNA ligase, cytoplasmic (SARS1) LDTP04265 0.84  LDD2103 
Serine/threonine-protein kinase A-Raf (ARAF) LDTP02493 0.88  LDD2103 
Serine/threonine-protein kinase Chk1 (CHEK1) LDTP00422 0.95  LDD2103 
Serine/threonine-protein kinase Chk2 (CHEK2) LDTP01754 1.20  LDD2103 
Serine/threonine-protein kinase PRP4 homolog (PRPF4B) LDTP05911 1.13  LDD2103 
Serine/threonine-protein kinase RIO2 (RIOK2) LDTP11299 0.96  LDD2103 
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A) LDTP05046 0.93  LDD2103 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 0.92  LDD2103 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 1.19  LDD2103 
Serine/threonine-protein phosphatase PGAM5, mitochondrial (PGAM5) LDTP10399 0.96  LDD2103 
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) LDTP04959 1.32  LDD2103 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 1.45; 1.20  LDD2103 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 0.87; 1.05; 0.98  LDD2103 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 1.07; 0.89; 0.94  LDD2103 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 0.71; 0.88  LDD2103 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 1.13; 0.80  LDD2103 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 0.94  LDD2103 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 1.10  LDD2103 
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1) LDTP04566 0.73  LDD2103 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 0.94; 1.13  LDD2103 
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) LDTP00931 0.93; 1.06  LDD2103 
Telomerase RNA component interacting RNase (TRIR) LDTP11055 1.00  LDD2103 
Thimet oligopeptidase (THOP1) LDTP04542 1.01  LDD2103 
Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 1.35  LDD2103 
THUMP domain-containing protein 2 (THUMPD2) LDTP18307 0.85  LDD2103 
Thymidine kinase, cytosolic (TK1) LDTP02022 0.82  LDD2103 
Thymidylate kinase (DTYMK) LDTP03258 0.90  LDD2103 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 1.09  LDD2103 
Transcriptional regulator ATRX (ATRX) LDTP04090 0.94  LDD2103 
Transforming protein RhoA (RHOA) LDTP04927 0.86; 1.69  LDD2103 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 0.77; 1.10  LDD2103 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 0.87  LDD2103 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 0.43; 1.41; 1.25  LDD2103 
Triosephosphate isomerase (TPI1) LDTP04851 1.33  LDD2103 
Tripeptidyl-peptidase 2 (TPP2) LDTP03469 1.00  LDD2103 
Tyrosine-protein kinase Yes (YES1) LDTP02231 0.98  LDD2103 
Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) LDTP02935 0.99; 1.05  LDD2103 
Tyrosine-protein phosphatase non-receptor type 2 (PTPN2) LDTP02917 1.09  LDD2103 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 1.31; 0.88  LDD2103 
Ubiquitin carboxyl-terminal hydrolase 10 (USP10) LDTP06190 1.05  LDD2103 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 0.92  LDD2103 
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) LDTP04074 1.11; 1.01  LDD2103 
Ubiquitin carboxyl-terminal hydrolase 7 (USP7) LDTP09962 0.87  LDD2103 
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) LDTP05070 1.16  LDD2103 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 0.96; 1.13  LDD2103 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 1.02; 0.84  LDD2103 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 0.72; 1.03  LDD2103 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 1.28  LDD2103 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 0.75  LDD2103 
Vascular endothelial growth factor receptor 3 (FLT4) LDTP03795 1.11  LDD2103 
Very long chain fatty acid elongase 5 (ELOVL5) LDTP12841 1.03  LDD2103 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 0.90  LDD2103 
WD repeat-containing protein 82 (WDR82) LDTP07715 1.25  LDD2103 
X-ray repair cross-complementing protein 5 (XRCC5) LDTP02642 1.29  LDD2103 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 0.94  LDD2103 
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⏷ Show the Full List of 309 Enzyme
112 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein theta (YWHAQ) LDTP03385 0.76  LDD2103 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 1.26  LDD2103 
Adaptin ear-binding coat-associated protein 2 (NECAP2) LDTP16115 1.01  LDD2103 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 0.99  LDD2103 
Annexin A1 (ANXA1) LDTP02010 1.48  LDD2103 
Annexin A6 (ANXA6) LDTP02247 0.77; 0.62  LDD2103 
AP-1 complex subunit beta-1 (AP1B1) LDTP05625 1.59; 1.19  LDD2103 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 1.11  LDD2103 
AP-2 complex subunit alpha-1 (AP2A1) LDTP01673 1.26; 1.51  LDD2103 
AP-2 complex subunit alpha-2 (AP2A2) LDTP01477 1.19  LDD2103 
AP-2 complex subunit beta (AP2B1) LDTP05038 0.83; 1.31  LDD2103 
Apoptosis regulator BAX (BAX) LDTP05528 1.39  LDD2103 
Apoptotic chromatin condensation inducer in the nucleus (ACIN1) LDTP13490 1.04; 0.98  LDD2103 
ATP-binding cassette sub-family F member 2 (ABCF2) LDTP18526 1.08  LDD2103 
BOS complex subunit NCLN (NCLN) LDTP10036 1.03  LDD2103 
Calreticulin (CALR) LDTP03402 1.22  LDD2103 
Catenin delta-1 (CTNND1) LDTP01037 1.11  LDD2103 
Cation-dependent mannose-6-phosphate receptor (M6PR) LDTP03061 0.86  LDD2103 
CD44 antigen (CD44) LDTP02823 0.82  LDD2103 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 1.11  LDD2103 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.94; 1.04; 1.03 ...  LDD2103 
Clathrin light chain B (CLTB) LDTP02353 1.15  LDD2103 
Copine-1 (CPNE1) LDTP10989 1.99  LDD2103 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 1.05  LDD2103 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 0.98  LDD2103 
Dysferlin (DYSF) LDTP01355 0.98  LDD2103 
Endoplasmic reticulum junction formation protein lunapark (LNPK) LDTP11609 1.03  LDD2103 
Eukaryotic translation initiation factor 5A-1-like (EIF5AL1) LDTP17347 0.78  LDD2103 
Exportin-1 (XPO1) LDTP00501 0.95; 1.01  LDD2103 
Exportin-2 (CSE1L) LDTP04662 1.05; 1.03; 1.06 ...  LDD2103 
Fatty acid-binding protein 5 (FABP5) LDTP05292 1.51; 1.42  LDD2103 
Filamin-A (FLNA) LDTP03107 1.06; 1.72; 1.15 ...  LDD2103 
Filamin-B (FLNB) LDTP01197 0.98; 1.08; 0.96 ...  LDD2103 
Filamin-C (FLNC) LDTP06103 0.94; 0.93; 1.11 ...  LDD2103 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) LDTP05017 1.02; 0.91; 1.23 ...  LDD2103 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) LDTP05020 1.05; 0.97  LDD2103 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 0.97; 1.01  LDD2103 
Histone deacetylase complex subunit SAP18 (SAP18) LDTP00270 0.87  LDD2103 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 1.02; 1.14  LDD2103 
Importin subunit alpha-7 (KPNA6) LDTP01031 0.89  LDD2103 
Importin subunit beta-1 (KPNB1) LDTP06242 1.35  LDD2103 
Importin-4 (IPO4) LDTP09515 1.17  LDD2103 
Importin-5 (IPO5) LDTP00266 1.07; 1.07; 1.17 ...  LDD2103 
Importin-7 (IPO7) LDTP01574 1.04; 0.89  LDD2103 
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) LDTP06153 0.99  LDD2103 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 0.89; 1.26  LDD2103 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 0.56  LDD2103 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 0.84  LDD2103 
MICOS complex subunit MIC10 (MICOS10) LDTP07191 1.19  LDD2103 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) LDTP13698 0.90; 1.00; 1.05 ...  LDD2103 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 1.01  LDD2103 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 0.98  LDD2103 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 1.18  LDD2103 
Myoferlin (MYOF) LDTP12916 0.96; 1.31; 1.11 ...  LDD2103 
Nuclear cap-binding protein subunit 1 (NCBP1) LDTP05591 0.97; 1.13  LDD2103 
Nuclear pore complex protein Nup153 (NUP153) LDTP04309 0.99; 1.08  LDD2103 
Nuclear pore complex protein Nup205 (NUP205) LDTP09825 0.91  LDD2103 
Nuclear pore complex protein Nup214 (NUP214) LDTP03777 0.97  LDD2103 
Nuclear pore complex protein Nup50 (NUP50) LDTP13498 0.81; 1.02  LDD2103 
Nuclear pore complex protein Nup85 (NUP85) LDTP11310 0.96  LDD2103 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 0.79  LDD2103 
Nucleoporin NDC1 (NDC1) LDTP11213 1.13  LDD2103 
Nucleoporin p58/p45 (NUP58) LDTP11293 0.90  LDD2103 
Nucleoprotein TPR (TPR) LDTP02612 0.86; 0.80; 0.68  LDD2103 
Oligosaccharyltransferase complex subunit OSTC (OSTC) LDTP12526 0.83  LDD2103 
Optineurin (OPTN) LDTP10189 1.09  LDD2103 
Phosphorylated adapter RNA export protein (PHAX) LDTP12043 0.93  LDD2103 
Podocalyxin (PODXL) LDTP00321 0.87; 0.77  LDD2103 
Prohibitin 1 (PHB1) LDTP03717 1.15  LDD2103 
Protein S100-A10 (S100A10) LDTP04885 0.62  LDD2103 
Protein SON (SON) LDTP02959 1.09  LDD2103 
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) LDTP04932 0.86  LDD2103 
Protein transport protein Sec61 subunit beta (SEC61B) LDTP04866 1.01  LDD2103 
Protein transport protein Sec61 subunit gamma (SEC61G) LDTP04850 0.77  LDD2103 
Ran GTPase-activating protein 1 (RANGAP1) LDTP04082 1.07  LDD2103 
Serine incorporator 3 (SERINC3) LDTP05913 1.04  LDD2103 
Signal recognition particle 14 kDa protein (SRP14) LDTP03837 1.02  LDD2103 
Signal recognition particle 9 kDa protein (SRP9) LDTP04259 0.98; 0.96  LDD2103 
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1) LDTP02068 1.13  LDD2103 
Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3) LDTP04624 0.69  LDD2103 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 0.97  LDD2103 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 0.95  LDD2103 
Sorting nexin-5 (SNX5) LDTP14174 0.98  LDD2103 
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 0.95  LDD2103 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 0.97  LDD2103 
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) LDTP10931 1.00  LDD2103 
T-complex protein 1 subunit delta (CCT4) LDTP04391 1.05  LDD2103 
Talin-1 (TLN1) LDTP14031 1.41; 1.00; 1.20 ...  LDD2103 
TBC1 domain family member 4 (TBC1D4) LDTP00958 1.03  LDD2103 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 0.98  LDD2103 
THO complex subunit 1 (THOC1) LDTP10317 1.09  LDD2103 
THO complex subunit 6 homolog (THOC6) LDTP08315 0.79  LDD2103 
THO complex subunit 7 homolog (THOC7) LDTP07397 1.02  LDD2103 
Transferrin receptor protein 1 (TFRC) LDTP01969 0.54  LDD2103 
Translocation protein SEC62 (SEC62) LDTP15838 1.46  LDD2103 
Translocation protein SEC63 homolog (SEC63) LDTP13243 0.84  LDD2103 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 1.12  LDD2103 
Transmembrane protein 214 (TMEM214) LDTP07477 1.02  LDD2103 
Transmembrane protein 33 (TMEM33) LDTP04787 0.74  LDD2103 
Transportin-1 (TNPO1) LDTP09949 1.07  LDD2103 
Transportin-3 (TNPO3) LDTP14133 1.07  LDD2103 
Tricarboxylate transport protein, mitochondrial (SLC25A1) LDTP04553 0.94  LDD2103 
Ubiquilin-4 (UBQLN4) LDTP12533 0.66  LDD2103 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 1.27  LDD2103 
Vacuolar protein sorting-associated protein 26B (VPS26B) LDTP17131 1.00  LDD2103 
Vacuolar protein sorting-associated protein 29 (VPS29) LDTP13142 1.02  LDD2103 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 1.01; 0.86; 0.79  LDD2103 
Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 0.95; 0.97  LDD2103 
Vesicle-associated membrane protein-associated protein B/C (VAPB) LDTP01556 1.33  LDD2103 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 1.38  LDD2103 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 1.18  LDD2103 
Zinc transporter 7 (SLC30A7) LDTP09180 2.71  LDD2103 
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⏷ Show the Full List of 112 Transporter and channel
15 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Cell division cycle 5-like protein (CDC5L) LDTP10868 0.90  LDD2103 
Dr1-associated corepressor (DRAP1) LDTP06229 0.77  LDD2103 
eIF5-mimic protein 1 (BZW2) LDTP14241 1.21  LDD2103 
Fos-related antigen 1 (FOSL1) LDTP02786 0.84  LDD2103 
Gamma-interferon-inducible protein 16 (IFI16) LDTP06602 0.51; 0.66  LDD2103 
Interferon regulatory factor 3 (IRF3) LDTP06168 0.68  LDD2103 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 0.88  LDD2103 
NF-kappa-B-repressing factor (NKRF) LDTP00576 1.19  LDD2103 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 1.34; 0.97  LDD2103 
Nuclear factor 1 C-type (NFIC) LDTP02296 0.94  LDD2103 
Nuclear factor NF-kappa-B p105 subunit (NFKB1) LDTP03017 0.95  LDD2103 
Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4) LDTP06231 1.07  LDD2103 
Proto-oncogene c-Rel (REL) LDTP05439 0.87  LDD2103 
Recombining binding protein suppressor of hairless (RBPJ) LDTP05485 0.32  LDD2103 
Transcription factor SOX-9 (SOX9) LDTP04179 1.01  LDD2103 
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⏷ Show the Full List of 15 Transcription factor
1 GPCR Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Adhesion G-protein coupled receptor G1 (ADGRG1) LDTP14207 0.93  LDD2103 
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2 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Basigin (BSG) LDTP03772 0.90  LDD2103 
CD166 antigen (ALCAM) LDTP05973 1.07  LDD2103 
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2 Cytokine and receptor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Endoglin (ENG) LDTP02923 1.52; 0.96  LDD2103 
Interleukin-6 receptor subunit beta (IL6ST) LDTP03881 0.84  LDD2103 
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334 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein sigma (SFN) LDTP03618 0.98  LDD2103 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 0.87  LDD2103 
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) LDTP06273 0.99  LDD2103 
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 1.10  LDD2103 
A-kinase anchor protein 1, mitochondrial (AKAP1) LDTP09837 1.04; 1.14  LDD2103 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 1.07  LDD2103 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 1.03  LDD2103 
Actin nucleation-promoting factor WASL (WASL) LDTP00263 0.91  LDD2103 
Actin-related protein 2/3 complex subunit 3 (ARPC3) LDTP00552 1.74  LDD2103 
Actin-related protein 3 (ACTR3) LDTP04902 0.92  LDD2103 
Active breakpoint cluster region-related protein (ABR) LDTP05713 0.89  LDD2103 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 1.50; 1.72  LDD2103 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 1.20  LDD2103 
Afadin (AFDN) LDTP04679 0.96  LDD2103 
Alpha-actinin-1 (ACTN1) LDTP02631 1.64  LDD2103 
Alpha-catulin (CTNNAL1) LDTP13159 0.79  LDD2103 
Alpha-parvin (PARVA) LDTP12671 0.85  LDD2103 
Alpha-soluble NSF attachment protein (NAPA) LDTP04647 0.84  LDD2103 
Anillin (ANLN) LDTP12443 0.78  LDD2103 
Annexin A4 (ANXA4) LDTP02354 1.51  LDD2103 
Annexin A7 (ANXA7) LDTP03030 1.49  LDD2103 
AP-3 complex subunit mu-1 (AP3M1) LDTP13908 0.66  LDD2103 
Armadillo repeat-containing protein 1 (ARMC1) LDTP12692 1.08  LDD2103 
Ataxin-2 (ATXN2) LDTP10947 0.71  LDD2103 
Bardet-Biedl syndrome 12 protein (BBS12) LDTP07861 1.27  LDD2103 
Barrier-to-autointegration factor (BANF1) LDTP01250 1.92; 0.96  LDD2103 
Bcl-2-associated transcription factor 1 (BCLAF1) LDTP12826 0.98  LDD2103 
Biorientation of chromosomes in cell division protein 1-like 1 (BOD1L1) LDTP09196 0.88  LDD2103 
BRCA1-associated ATM activator 1 (BRAT1) LDTP07598 0.91  LDD2103 
BRCA2 and CDKN1A-interacting protein (BCCIP) LDTP13030 1.21  LDD2103 
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A) LDTP12518 0.93  LDD2103 
Calcium homeostasis endoplasmic reticulum protein (CHERP) LDTP08570 1.29  LDD2103 
Calmegin (CLGN) LDTP00493 0.96  LDD2103 
Calpastatin (CAST) LDTP03079 0.99  LDD2103 
cAMP-dependent protein kinase type I-beta regulatory subunit (PRKAR1B) LDTP03589 0.84  LDD2103 
Caprin-1 (CAPRIN1) LDTP06121 1.01  LDD2103 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 0.74; 1.06; 1.14  LDD2103 
CCN family member 5 (CCN5) LDTP01395 1.10  LDD2103 
CCR4-NOT transcription complex subunit 2 (CNOT2) LDTP12925 1.49  LDD2103 
Centromere protein F (CENPF) LDTP04258 1.16  LDD2103 
Centromere/kinetochore protein zw10 homolog (ZW10) LDTP00720 1.44; 0.82  LDD2103 
Centrosomal protein of 170 kDa (CEP170) LDTP07071 1.03; 0.90  LDD2103 
Charged multivesicular body protein 1a (CHMP1A) LDTP12285 0.86  LDD2103 
Charged multivesicular body protein 5 (CHMP5) LDTP12948 0.94  LDD2103 
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6) LDTP06584 0.86; 1.13  LDD2103 
Cleavage stimulation factor subunit 2 (CSTF2) LDTP03665 0.88  LDD2103 
Clustered mitochondria protein homolog (CLUH) LDTP14486 1.14  LDD2103 
Coactosin-like protein (COTL1) LDTP06024 1.13  LDD2103 
Coatomer subunit alpha (COPA) LDTP04571 0.77; 0.92; 0.72  LDD2103 
Coatomer subunit beta (COPB1) LDTP04570 0.72; 1.04; 1.13  LDD2103 
Cofilin-1 (CFL1) LDTP03244 0.71; 0.96; 1.28 ...  LDD2103 
Cofilin-2 (CFL2) LDTP13827 2.19  LDD2103 
Coiled-coil domain-containing protein 25 (CCDC25) LDTP08339 0.88  LDD2103 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 0.98  LDD2103 
Complex III assembly factor LYRM7 (LYRM7) LDTP07200 0.77  LDD2103 
Condensin complex subunit 1 (NCAPD2) LDTP06281 1.00; 0.92  LDD2103 
Condensin complex subunit 2 (NCAPH) LDTP06268 0.99  LDD2103 
Condensin-2 complex subunit G2 (NCAPG2) LDTP08359 1.00  LDD2103 
COP9 signalosome complex subunit 1 (GPS1) LDTP05746 1.54; 0.79  LDD2103 
Core histone macro-H2A.1 (MACROH2A1) LDTP01195 0.69  LDD2103 
Coronin-1B (CORO1B) LDTP11101 0.85  LDD2103 
Coronin-1C (CORO1C) LDTP13580 0.95; 0.91; 1.09 ...  LDD2103 
Crk-like protein (CRKL) LDTP04092 0.90  LDD2103 
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) LDTP13269 0.89  LDD2103 
Cysteine-rich hydrophobic domain-containing protein 2 (CHIC2) LDTP13458 1.14  LDD2103 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 1.01; 0.98; 0.89 ...  LDD2103 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 1.65  LDD2103 
Cytoplasmic FMR1-interacting protein 2 (CYFIP2) LDTP10289 1.58  LDD2103 
Cytoskeleton-associated protein 5 (CKAP5) LDTP06021 1.10  LDD2103 
Cytosolic Fe-S cluster assembly factor NUBP1 (NUBP1) LDTP04560 1.23  LDD2103 
DAZ-associated protein 1 (DAZAP1) LDTP10271 0.96; 1.23  LDD2103 
DDB1- and CUL4-associated factor 7 (DCAF7) LDTP04947 0.88  LDD2103 
Dedicator of cytokinesis protein 7 (DOCK7) LDTP10613 0.82  LDD2103 
Destrin (DSTN) LDTP04887 1.07  LDD2103 
DNA fragmentation factor subunit alpha (DFFA) LDTP00239 0.74  LDD2103 
DNA mismatch repair protein Msh2 (MSH2) LDTP04028 1.16  LDD2103 
DNA mismatch repair protein Msh6 (MSH6) LDTP04518 0.83; 1.18  LDD2103 
DnaJ homolog subfamily A member 1 (DNAJA1) LDTP03606 1.17  LDD2103 
DnaJ homolog subfamily C member 7 (DNAJC7) LDTP10920 1.00  LDD2103 
Dynactin subunit 1 (DCTN1) LDTP06082 0.79  LDD2103 
Dynein axonemal assembly factor 5 (DNAAF5) LDTP08387 1.01; 0.81  LDD2103 
Dysbindin (DTNBP1) LDTP10279 0.45  LDD2103 
Early endosome antigen 1 (EEA1) LDTP06310 0.97  LDD2103 
Elongation factor 1-gamma (EEF1G) LDTP03367 3.10  LDD2103 
Elongator complex protein 2 (ELP2) LDTP07400 1.01  LDD2103 
Elongin-B (ELOB) LDTP06369 0.90  LDD2103 
Endoplasmin (HSP90B1) LDTP02734 1.16  LDD2103 
Engulfment and cell motility protein 1 (ELMO1) LDTP09794 1.05; 1.12  LDD2103 
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8L2) LDTP11998 0.91  LDD2103 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 0.94; 1.45; 1.07  LDD2103 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 0.82; 1.07  LDD2103 
Eukaryotic translation initiation factor 3 subunit E (EIF3E) LDTP04853 1.12  LDD2103 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 0.96  LDD2103 
Eukaryotic translation initiation factor 3 subunit K (EIF3K) LDTP13143 1.54  LDD2103 
Eukaryotic translation initiation factor 3 subunit M (EIF3M) LDTP07947 1.54  LDD2103 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 0.81  LDD2103 
F-actin-capping protein subunit beta (CAPZB) LDTP04127 0.94  LDD2103 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 1.00  LDD2103 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 1.26  LDD2103 
Far upstream element-binding protein 3 (FUBP3) LDTP10408 0.98  LDD2103 
Galectin-1 (LGALS1) LDTP02341 0.91; 1.55; 1.07  LDD2103 
General transcription factor 3C polypeptide 5 (GTF3C5) LDTP14147 0.93  LDD2103 
General vesicular transport factor p115 (USO1) LDTP01048 1.06  LDD2103 
Gephyrin (GPHN) LDTP12448 1.12  LDD2103 
Girdin (CCDC88A) LDTP06804 1.09  LDD2103 
Golgin subfamily A member 2 (GOLGA2) LDTP05557 0.86  LDD2103 
Golgin subfamily A member 3 (GOLGA3) LDTP05556 1.10  LDD2103 
GRIP1-associated protein 1 (GRIPAP1) LDTP06864 0.95  LDD2103 
GrpE protein homolog 1, mitochondrial (GRPEL1) LDTP12144 0.96  LDD2103 
Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2) LDTP02059 1.01  LDD2103 
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (GNG5) LDTP05054 1.16  LDD2103 
H/ACA ribonucleoprotein complex subunit 3 (NOP10) LDTP12350 0.90  LDD2103 
HEAT repeat-containing protein 1 (HEATR1) LDTP11948 1.05  LDD2103 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.89  LDD2103 
Heat shock protein 105 kDa (HSPH1) LDTP09811 0.90; 0.98; 0.96  LDD2103 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 0.79  LDD2103 
Hepatoma-derived growth factor (HDGF) LDTP04483 1.06; 0.98  LDD2103 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 1.17  LDD2103 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 1.14  LDD2103 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 1.08  LDD2103 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 1.03; 1.07; 0.97  LDD2103 
Heterogeneous nuclear ribonucleoprotein L (HNRNPL) LDTP02750 1.02; 1.40  LDD2103 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 1.10; 0.81; 0.98 ...  LDD2103 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 0.94  LDD2103 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 1.13; 1.03; 0.96  LDD2103 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 0.98  LDD2103 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 0.75; 1.05  LDD2103 
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) LDTP02227 1.26  LDD2103 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 1.04  LDD2103 
Host cell factor 1 (HCFC1) LDTP04434 1.22  LDD2103 
Inner centromere protein (INCENP) LDTP12432 1.09  LDD2103 
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) LDTP14272 1.01  LDD2103 
Integrin alpha-3 (ITGA3) LDTP03342 1.00  LDD2103 
Interleukin enhancer-binding factor 3 (ILF3) LDTP05689 1.23  LDD2103 
Katanin p80 WD40 repeat-containing subunit B1 (KATNB1) LDTP11276 1.01  LDD2103 
Kinectin (KTN1) LDTP08238 0.92  LDD2103 
La-related protein 4B (LARP4B) LDTP09820 1.05  LDD2103 
Lamin-B1 (LMNB1) LDTP03065 1.63  LDD2103 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 1.11; 1.09  LDD2103 
Large ribosomal subunit protein eL14 (RPL14) LDTP04389 0.88  LDD2103 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 1.26; 0.80  LDD2103 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 0.97; 0.91  LDD2103 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 0.63; 0.82  LDD2103 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 0.90; 0.62  LDD2103 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 1.00  LDD2103 
Large ribosomal subunit protein eL42 (RPL36A) LDTP05188 0.86  LDD2103 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 0.55  LDD2103 
Large ribosomal subunit protein mL38 (MRPL38) LDTP10232 0.80  LDD2103 
Large ribosomal subunit protein mL50 (MRPL50) LDTP15429 0.88  LDD2103 
Large ribosomal subunit protein uL1 (RPL10A) LDTP05024 1.24; 1.29  LDD2103 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 0.98  LDD2103 
Large ribosomal subunit protein uL11 (RPL12) LDTP03517 1.14  LDD2103 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 0.92  LDD2103 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 0.88; 0.79  LDD2103 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 0.95  LDD2103 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 0.79; 0.77; 1.02  LDD2103 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 1.38; 1.01  LDD2103 
Large ribosomal subunit protein uL5 (RPL11) LDTP05026 1.06; 1.08; 0.71  LDD2103 
Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) LDTP03658 1.09; 0.88  LDD2103 
LEM domain-containing protein 2 (LEMD2) LDTP09082 1.02; 1.07  LDD2103 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 1.04; 1.01; 1.09 ...  LDD2103 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 1.45  LDD2103 
Matrin-3 (MATR3) LDTP04027 0.70  LDD2103 
Mediator of RNA polymerase II transcription subunit 15 (MED15) LDTP10771 0.76  LDD2103 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 1.08  LDD2103 
Meiotic nuclear division protein 1 homolog (MND1) LDTP18320 0.64  LDD2103 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 0.84  LDD2103 
Microtubule-associated protein 4 (MAP4) LDTP03404 0.66; 0.90  LDD2103 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 1.01  LDD2103 
Mitochondrial antiviral-signaling protein (MAVS) LDTP08058 1.11  LDD2103 
Mitochondrial import receptor subunit TOM70 (TOMM70) LDTP01432 0.85  LDD2103 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.96; 0.95  LDD2103 
MKI67 FHA domain-interacting nucleolar phosphoprotein (NIFK) LDTP11457 0.77  LDD2103 
Nestin (NES) LDTP04206 0.73  LDD2103 
Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 1.00; 0.90  LDD2103 
NHP2-like protein 1 (SNU13) LDTP04708 1.03; 0.92  LDD2103 
Nonsense-mediated mRNA decay factor SMG8 (SMG8) LDTP09112 0.83  LDD2103 
Nonsense-mediated mRNA decay factor SMG9 (SMG9) LDTP11737 1.05  LDD2103 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 1.11  LDD2103 
Nuclear mitotic apparatus protein 1 (NUMA1) LDTP06244 1.24; 1.00; 0.78 ...  LDD2103 
Nucleolar protein 11 (NOL11) LDTP16017 1.09  LDD2103 
Nucleolar protein 16 (NOP16) LDTP16278 0.97  LDD2103 
Nucleolar protein 56 (NOP56) LDTP00313 1.00  LDD2103 
Nucleolar protein 58 (NOP58) LDTP13925 1.25  LDD2103 
Nucleolin (NCL) LDTP02990 1.09  LDD2103 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 0.76  LDD2103 
NudC domain-containing protein 1 (NUDCD1) LDTP10781 1.13  LDD2103 
OCIA domain-containing protein 2 (OCIAD2) LDTP17157 1.32; 0.83  LDD2103 
PCNA-associated factor (PCLAF) LDTP06269 0.96  LDD2103 
Pentraxin-related protein PTX3 (PTX3) LDTP03345 1.11  LDD2103 
Peroxiredoxin-like 2A (PRXL2A) LDTP11140 1.06  LDD2103 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 1.25  LDD2103 
Plastin-2 (LCP1) LDTP02691 0.94  LDD2103 
Plectin (PLEC) LDTP06330 1.04; 1.01; 0.98 ...  LDD2103 
Poly(rC)-binding protein 3 (PCBP3) LDTP04793 1.31  LDD2103 
Polyadenylate-binding protein-interacting protein 1 (PAIP1) LDTP11682 0.89  LDD2103 
Pre-mRNA-processing factor 6 (PRPF6) LDTP01456 0.70  LDD2103 
Pre-mRNA-processing-splicing factor 8 (PRPF8) LDTP07526 0.86  LDD2103 
Pre-mRNA-splicing factor 38B (PRPF38B) LDTP17266 0.79  LDD2103 
Pre-mRNA-splicing factor ISY1 homolog (ISY1) LDTP13570 1.05  LDD2103 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 0.98  LDD2103 
Proliferating cell nuclear antigen (PCNA) LDTP02596 0.67  LDD2103 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 0.69; 1.37; 0.59 ...  LDD2103 
Proline-rich AKT1 substrate 1 (AKT1S1) LDTP10111 1.08  LDD2103 
Proteasomal ubiquitin receptor ADRM1 (ADRM1) LDTP06514 1.22  LDD2103 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 1.18; 0.91; 1.11  LDD2103 
Proteasome assembly chaperone 1 (PSMG1) LDTP01608 0.97  LDD2103 
Protein DEK (DEK) LDTP03778 1.01  LDD2103 
Protein ECT2 (ECT2) LDTP12067 0.99; 0.86  LDD2103 
Protein FAM98A (FAM98A) LDTP09086 1.03  LDD2103 
Protein HGH1 homolog (HGH1) LDTP18309 1.20  LDD2103 
Protein IWS1 homolog (IWS1) LDTP10822 1.22  LDD2103 
Protein jagged-2 (JAG2) LDTP13778 0.71  LDD2103 
Protein LSM12 (LSM12) LDTP06780 1.06  LDD2103 
Protein MON2 homolog (MON2) LDTP08041 1.01  LDD2103 
Protein Niban 1 (NIBAN1) LDTP11559 1.00  LDD2103 
Protein Niban 2 (NIBAN2) LDTP10847 1.13; 1.21  LDD2103 
Protein NipSnap homolog 2 (NIPSNAP2) LDTP01174 0.80  LDD2103 
Protein PRRC2C (PRRC2C) LDTP14085 1.07  LDD2103 
Protein RCC2 (RCC2) LDTP13020 1.37  LDD2103 
Protein SGT1 homolog (SUGT1) LDTP13935 0.66  LDD2103 
Protein strawberry notch homolog 1 (SBNO1) LDTP14337 0.96  LDD2103 
Pumilio homolog 3 (PUM3) LDTP06377 0.98  LDD2103 
Putative RNA-binding protein Luc7-like 1 (LUC7L) LDTP12388 1.09  LDD2103 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 1.10  LDD2103 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 2.13  LDD2103 
Rab3 GTPase-activating protein non-catalytic subunit (RAB3GAP2) LDTP11833 1.03  LDD2103 
Ral GTPase-activating protein subunit beta (RALGAPB) LDTP15308 1.01  LDD2103 
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) LDTP07878 0.90  LDD2103 
RCC1 domain-containing protein 1 (RCCD1) LDTP00091 0.91  LDD2103 
Regulator of nonsense transcripts 3A (UPF3A) LDTP11767 0.81  LDD2103 
Replication protein A 14 kDa subunit (RPA3) LDTP03723 1.07  LDD2103 
Replication termination factor 2 (RTF2) LDTP11434 1.12  LDD2103 
Reticulon-3 (RTN3) LDTP01522 1.23  LDD2103 
Reticulon-4 (RTN4) LDTP12412 1.10  LDD2103 
Rho guanine nucleotide exchange factor 1 (ARHGEF1) LDTP09917 1.04  LDD2103 
Ribonucleoprotein PTB-binding 1 (RAVER1) LDTP15356 1.58  LDD2103 
Ribosomal L1 domain-containing protein 1 (RSL1D1) LDTP01379 1.04; 1.06  LDD2103 
Ribosomal RNA processing protein 1 homolog A (RRP1) LDTP04729 0.88  LDD2103 
Ribosome biogenesis protein BRX1 homolog (BRIX1) LDTP15609 0.95  LDD2103 
Ribosome-binding protein 1 (RRBP1) LDTP13044 0.99; 0.70; 1.23  LDD2103 
RNA-binding protein 4B (RBM4B) LDTP11046 0.96  LDD2103 
RNA-binding protein Raly (RALY) LDTP13467 1.26  LDD2103 
RNA-binding protein RO60 (RO60) LDTP02480 1.01  LDD2103 
SAFB-like transcription modulator (SLTM) LDTP12717 0.84  LDD2103 
Scaffold attachment factor B2 (SAFB2) LDTP06054 0.79  LDD2103 
Sequestosome-1 (SQSTM1) LDTP05898 0.76  LDD2103 
Serine/arginine repetitive matrix protein 2 (SRRM2) LDTP13746 0.83; 0.74  LDD2103 
Serine/arginine-rich splicing factor 1 (SRSF1) LDTP05539 1.05  LDD2103 
Serine/arginine-rich splicing factor 11 (SRSF11) LDTP05458 0.83  LDD2103 
Serine/arginine-rich splicing factor 3 (SRSF3) LDTP05197 1.12; 1.09  LDD2103 
Serine/arginine-rich splicing factor 6 (SRSF6) LDTP05802 0.84  LDD2103 
Serine/threonine-protein phosphatase 6 regulatory subunit 1 (PPP6R1) LDTP13701 0.86  LDD2103 
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (PPP6R3) LDTP06983 0.93  LDD2103 
SERPINE1 mRNA-binding protein 1 (SERBP1) LDTP09081 0.94  LDD2103 
Serrate RNA effector molecule homolog (SRRT) LDTP11398 1.24; 1.09; 0.97  LDD2103 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 1.05  LDD2103 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 0.82  LDD2103 
Small nuclear ribonucleoprotein Sm D2 (SNRPD2) LDTP04982 1.18  LDD2103 
Small nuclear ribonucleoprotein Sm D3 (SNRPD3) LDTP04983 1.42  LDD2103 
Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB) LDTP02741 1.29  LDD2103 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 1.05; 1.18; 1.20 ...  LDD2103 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 1.45; 1.48; 0.99  LDD2103 
Small ribosomal subunit protein eS17 (RPS17) LDTP02302 0.74  LDD2103 
Small ribosomal subunit protein eS21 (RPS21) LDTP05055 0.77  LDD2103 
Small ribosomal subunit protein eS25 (RPS25) LDTP05013 1.06  LDD2103 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 1.14  LDD2103 
Small ribosomal subunit protein eS28 (RPS28) LDTP05015 1.12  LDD2103 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 0.93  LDD2103 
Small ribosomal subunit protein eS6 (RPS6) LDTP05002 0.98  LDD2103 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 0.93; 0.98  LDD2103 
Small ribosomal subunit protein mS27 (MRPS27) LDTP09793 0.92  LDD2103 
Small ribosomal subunit protein mS35 (MRPS35) LDTP14788 0.80  LDD2103 
Small ribosomal subunit protein uS10 (RPS20) LDTP04880 1.11; 0.87  LDD2103 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 1.09; 0.76  LDD2103 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 1.51; 0.91  LDD2103 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 1.03  LDD2103 
Small ribosomal subunit protein uS8 (RPS15A) LDTP04965 1.05; 1.54  LDD2103 
Small ribosomal subunit protein uS9 (RPS16) LDTP04966 0.98  LDD2103 
Small ubiquitin-related modifier 1 (SUMO1) LDTP05048 1.09  LDD2103 
Smoothelin (SMTN) LDTP04590 0.94  LDD2103 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 0.96  LDD2103 
Spermatid perinuclear RNA-binding protein (STRBP) LDTP10815 1.04  LDD2103 
Splicing factor 1 (SF1) LDTP06429 0.85  LDD2103 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 1.14; 1.09  LDD2103 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 0.73; 1.00  LDD2103 
SRA stem-loop-interacting RNA-binding protein, mitochondrial (SLIRP) LDTP11645 1.11  LDD2103 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 1.05  LDD2103 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 0.74; 0.61; 1.13 ...  LDD2103 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 1.53; 0.75; 1.34 ...  LDD2103 
Striatin-4 (STRN4) LDTP12519 1.10  LDD2103 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 0.98; 1.01  LDD2103 
Synaptogyrin-2 (SYNGR2) LDTP00859 0.79  LDD2103 
Synaptophysin-like protein 1 (SYPL1) LDTP06557 1.04  LDD2103 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 1.02  LDD2103 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 1.54; 0.89; 1.35 ...  LDD2103 
T-complex protein 1 subunit eta (CCT7) LDTP10990 2.33; 0.92; 1.33  LDD2103 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 1.12; 1.51  LDD2103 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.98; 1.38  LDD2103 
TAR DNA-binding protein 43 (TARDBP) LDTP05767 0.96  LDD2103 
Targeting protein for Xklp2 (TPX2) LDTP13583 1.34  LDD2103 
Testis-expressed protein 264 (TEX264) LDTP14259 1.23  LDD2103 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 1.14  LDD2103 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 1.57  LDD2103 
Tight junction protein ZO-2 (TJP2) LDTP13192 1.03  LDD2103 
Transcription elongation factor A protein-like 4 (TCEAL4) LDTP18149 0.78  LDD2103 
Transcription elongation factor SPT5 (SUPT5H) LDTP00236 0.91  LDD2103 
Transgelin-2 (TAGLN2) LDTP03846 0.92  LDD2103 
Translation machinery-associated protein 16 (TMA16) LDTP10283 1.01  LDD2103 
Translationally-controlled tumor protein (TPT1) LDTP02683 0.90  LDD2103 
Transmembrane protein 161A (TMEM161A) LDTP12762 1.02  LDD2103 
Transmembrane protein 209 (TMEM209) LDTP18272 1.20  LDD2103 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 0.97  LDD2103 
Tubulin beta-6 chain (TUBB6) LDTP11233 0.63  LDD2103 
Tubulin-folding cofactor B (TBCB) LDTP10860 0.98  LDD2103 
Tubulin-specific chaperone E (TBCE) LDTP06479 0.90  LDD2103 
Twinfilin-2 (TWF2) LDTP07404 1.05  LDD2103 
U1 small nuclear ribonucleoprotein C (SNRPC) LDTP02335 1.06  LDD2103 
U2 snRNP-associated SURP motif-containing protein (U2SURP) LDTP00517 0.78  LDD2103 
U3 small nucleolar ribonucleoprotein protein MPP10 (MPHOSPH10) LDTP00312 0.94  LDD2103 
U3 small nucleolar RNA-associated protein 6 homolog (UTP6) LDTP12830 0.87  LDD2103 
U4/U6 small nuclear ribonucleoprotein Prp31 (PRPF31) LDTP09671 0.82  LDD2103 
Ubiquitin-like protein 5 (UBL5) LDTP11545 1.08  LDD2103 
Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) LDTP05033 1.20  LDD2103 
UPF0449 protein C19orf25 (C19orf25) LDTP13214 1.05  LDD2103 
Vigilin (HDLBP) LDTP05239 0.57; 1.12; 0.53  LDD2103 
Vimentin (VIM) LDTP02297 0.99  LDD2103 
Vinculin (VCL) LDTP02946 0.94; 0.86; 1.47  LDD2103 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.25  LDD2103 
WD repeat-containing protein 1 (WDR1) LDTP01118 1.14  LDD2103 
WW domain-containing adapter protein with coiled-coil (WAC) LDTP11191 0.78  LDD2103 
Zinc finger C3HC-type protein 1 (ZC3HC1) LDTP08325 1.14  LDD2103 
Zinc finger protein 185 (ZNF185) LDTP00580 0.89; 1.44; 0.72  LDD2103 
Zinc finger RNA-binding protein (ZFR) LDTP15762 0.84; 0.92; 1.04  LDD2103 
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Full Information of The Labelling Profiles of This Competitor

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 5 mM
Quantitative Method Isotope tag
Experimemt Name ISO-TOP ABPP
Competitor Name 3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile
Competitor Concentration 0.5 mM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cell lysate (MDA-MB-231)
Interaction Atlas ID  LDD2103  Download The Altas

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761