Details of the Target

General Information of Target

Target ID LDTP08570
Target Name Calcium homeostasis endoplasmic reticulum protein (CHERP)
Gene Name CHERP
Gene ID 10523
Synonyms
DAN26; SCAF6; Calcium homeostasis endoplasmic reticulum protein; ERPROT 213-21; SR-related CTD-associated factor 6
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKL
ALEQQQLICKQQTPELEPAATMPPLPQPPLAPAAPIPPAQGAPSMDELIQQSQWNLQQQE
QHLLALRQEQVTAAVAHAVEQQMQKLLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWM
FSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKV
VVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYS
SVVQPVQLAFQQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAP
PPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPP
WFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPW
NNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPH
PHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINE
HPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVK
LEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAK
MRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSR
SRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLG
EENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRN
KSYSFIARMKARDECK
Target Bioclass
Other
Subcellular location
Cytoplasm
Function Involved in calcium homeostasis, growth and proliferation.
Uniprot ID
Q8IWX8
Ensemble ID
ENST00000546361.7
HGNC ID
HGNC:16930

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 37 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
TH211
 Probe Info  		Y897(8.95)  LDD0257  [2]
TH216
 Probe Info  		Y897(6.28)  LDD0259  [2]
STPyne
 Probe Info  		K177(9.68); K901(4.29)  LDD0277  [3]
Probe 1
 Probe Info  		Y894(16.95); Y903(21.43)  LDD3495  [4]
JZ128-DTB
 Probe Info  		N.A.  LDD0462  [5]
BTD
 Probe Info  		C69(1.18)  LDD2090  [6]
AHL-Pu-1
 Probe Info  		C915(3.01)  LDD0168  [7]
HHS-475
 Probe Info  		Y714(0.60); Y897(0.61)  LDD0264  [8]
HHS-465
 Probe Info  		Y714(7.84)  LDD2237  [9]
Acrolein
 Probe Info  		N.A.  LDD0221  [10]
DBIA
 Probe Info  		C246(2.21); C69(1.52)  LDD0080  [11]
5E-2FA
 Probe Info  		N.A.  LDD2235  [12]
4-Iodoacetamidophenylacetylene
 Probe Info  		C69(0.00); C225(0.00); C168(0.00); C190(0.00)  LDD0038  [13]
IA-alkyne
 Probe Info  		C69(0.00); C225(0.00); C168(0.00); C190(0.00)  LDD0036  [13]
IPIAA_H
 Probe Info  		N.A.  LDD0030  [14]
IPIAA_L
 Probe Info  		N.A.  LDD0031  [14]
Lodoacetamide azide
 Probe Info  		C69(0.00); C168(0.00); C190(0.00); C246(0.00)  LDD0037  [13]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [15]
NAIA_4
 Probe Info  		N.A.  LDD2226  [16]
TFBX
 Probe Info  		N.A.  LDD0027  [15]
WYneN
 Probe Info  		N.A.  LDD0021  [17]
Compound 10
 Probe Info  		N.A.  LDD2216  [18]
Compound 11
 Probe Info  		N.A.  LDD2213  [18]
ENE
 Probe Info  		N.A.  LDD0006  [17]
IPM
 Probe Info  		N.A.  LDD0005  [17]
PF-06672131
 Probe Info  		N.A.  LDD0017  [19]
PPMS
 Probe Info  		N.A.  LDD0008  [17]
SF
 Probe Info  		Y897(0.00); K256(0.00); K259(0.00); Y894(0.00)  LDD0028  [20]
Phosphinate-6
 Probe Info  		C915(0.00); C58(0.00); C190(0.00)  LDD0018  [21]
1c-yne
 Probe Info  		N.A.  LDD0228  [22]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [10]
Methacrolein
 Probe Info  		N.A.  LDD0218  [10]
W1
 Probe Info  		C69(0.00); C225(0.00); C246(0.00)  LDD0236  [23]
AOyne
 Probe Info  		11.50  LDD0443  [24]
NAIA_5
 Probe Info  		C190(0.00); C69(0.00); C225(0.00); C168(0.00)  LDD2223  [16]
HHS-482
 Probe Info  		Y714(1.10)  LDD2239  [9]
PAL-AfBPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe13
 Probe Info  		12.84  LDD0475  [25]
FFF probe14
 Probe Info  		20.00  LDD0477  [25]
FFF probe2
 Probe Info  		13.39  LDD0463  [25]
FFF probe3
 Probe Info  		14.02  LDD0464  [25]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C69(0.71); C190(0.78)  LDD2142  [6]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C69(1.71); C190(0.72)  LDD2112  [6]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C69(0.81)  LDD2095  [6]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C69(1.01)  LDD2130  [6]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C69(0.97); C190(1.18)  LDD2117  [6]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C69(1.29)  LDD2103  [6]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C69(0.81)  LDD2131  [6]
 LDCM0025  4SU-RNA HEK-293T C915(3.01)  LDD0168  [7]
 LDCM0026  4SU-RNA+native RNA HEK-293T C69(2.30)  LDD0169  [7]
 LDCM0214  AC1 HCT 116 C190(0.82); C69(1.24)  LDD0531  [11]
 LDCM0215  AC10 HCT 116 C190(0.99); C69(1.19)  LDD0532  [11]
 LDCM0216  AC100 HCT 116 C190(0.81); C69(0.98)  LDD0533  [11]
 LDCM0217  AC101 HCT 116 C190(0.83); C69(0.92)  LDD0534  [11]
 LDCM0218  AC102 HCT 116 C190(0.86); C69(0.98)  LDD0535  [11]
 LDCM0219  AC103 HCT 116 C190(0.84); C69(1.14)  LDD0536  [11]
 LDCM0220  AC104 HCT 116 C190(0.87); C69(1.03)  LDD0537  [11]
 LDCM0221  AC105 HCT 116 C190(0.81); C69(1.01)  LDD0538  [11]
 LDCM0222  AC106 HCT 116 C190(0.87); C69(1.14)  LDD0539  [11]
 LDCM0223  AC107 HCT 116 C190(0.88); C69(1.04)  LDD0540  [11]
 LDCM0224  AC108 HCT 116 C190(0.84); C69(0.92)  LDD0541  [11]
 LDCM0225  AC109 HCT 116 C190(0.86); C69(0.89)  LDD0542  [11]
 LDCM0226  AC11 HCT 116 C190(1.03); C69(1.35)  LDD0543  [11]
 LDCM0227  AC110 HCT 116 C190(0.82); C69(0.86)  LDD0544  [11]
 LDCM0228  AC111 HCT 116 C190(0.83); C69(0.90)  LDD0545  [11]
 LDCM0229  AC112 HCT 116 C190(0.79); C69(0.90)  LDD0546  [11]
 LDCM0230  AC113 HCT 116 C190(0.97); C246(1.05); C69(0.98)  LDD0547  [11]
 LDCM0231  AC114 HCT 116 C190(0.99); C246(1.21); C69(1.08)  LDD0548  [11]
 LDCM0232  AC115 HCT 116 C190(1.02); C246(1.05); C69(1.22)  LDD0549  [11]
 LDCM0233  AC116 HCT 116 C190(1.00); C246(0.96); C69(1.26)  LDD0550  [11]
 LDCM0234  AC117 HCT 116 C190(1.00); C246(1.11); C69(1.17)  LDD0551  [11]
 LDCM0235  AC118 HCT 116 C190(1.02); C246(0.89); C69(1.13)  LDD0552  [11]
 LDCM0236  AC119 HCT 116 C190(1.07); C246(0.84); C69(1.20)  LDD0553  [11]
 LDCM0237  AC12 HCT 116 C190(1.08); C69(1.14)  LDD0554  [11]
 LDCM0238  AC120 HCT 116 C190(1.03); C246(0.67); C69(1.20)  LDD0555  [11]
 LDCM0239  AC121 HCT 116 C190(1.04); C246(0.82); C69(1.13)  LDD0556  [11]
 LDCM0240  AC122 HCT 116 C190(1.06); C246(0.86); C69(1.07)  LDD0557  [11]
 LDCM0241  AC123 HCT 116 C190(0.95); C246(0.90); C69(1.08)  LDD0558  [11]
 LDCM0242  AC124 HCT 116 C190(0.97); C246(0.84); C69(1.05)  LDD0559  [11]
 LDCM0243  AC125 HCT 116 C190(1.02); C246(1.04); C69(1.03)  LDD0560  [11]
 LDCM0244  AC126 HCT 116 C190(1.12); C246(1.06); C69(1.20)  LDD0561  [11]
 LDCM0245  AC127 HCT 116 C190(1.12); C246(1.00); C69(1.20)  LDD0562  [11]
 LDCM0246  AC128 HCT 116 C190(1.12); C69(1.21)  LDD0563  [11]
 LDCM0247  AC129 HCT 116 C190(0.70); C69(0.90)  LDD0564  [11]
 LDCM0249  AC130 HCT 116 C190(0.85); C69(1.14)  LDD0566  [11]
 LDCM0250  AC131 HCT 116 C190(0.76); C69(0.88)  LDD0567  [11]
 LDCM0251  AC132 HCT 116 C190(1.03); C69(1.00)  LDD0568  [11]
 LDCM0252  AC133 HCT 116 C190(1.23); C69(1.05)  LDD0569  [11]
 LDCM0253  AC134 HCT 116 C190(1.39); C69(1.12)  LDD0570  [11]
 LDCM0254  AC135 HCT 116 C190(1.08); C69(1.14)  LDD0571  [11]
 LDCM0255  AC136 HCT 116 C190(1.40); C69(1.18)  LDD0572  [11]
 LDCM0256  AC137 HCT 116 C190(0.92); C69(1.10)  LDD0573  [11]
 LDCM0257  AC138 HCT 116 C190(0.87); C69(1.31)  LDD0574  [11]
 LDCM0258  AC139 HCT 116 C190(1.09); C69(1.23)  LDD0575  [11]
 LDCM0259  AC14 HCT 116 C190(1.03); C69(1.18)  LDD0576  [11]
 LDCM0260  AC140 HCT 116 C190(0.99); C69(1.28)  LDD0577  [11]
 LDCM0261  AC141 HCT 116 C190(0.99); C69(1.23)  LDD0578  [11]
 LDCM0262  AC142 HCT 116 C190(1.04); C69(1.03)  LDD0579  [11]
 LDCM0263  AC143 HCT 116 C190(1.00); C246(1.07); C69(1.11)  LDD0580  [11]
 LDCM0264  AC144 HCT 116 C190(1.12); C69(1.12); C246(1.22)  LDD0581  [11]
 LDCM0265  AC145 HCT 116 C246(0.99); C190(1.01); C69(1.12)  LDD0582  [11]
 LDCM0266  AC146 HCT 116 C246(0.98); C190(1.05); C69(1.14)  LDD0583  [11]
 LDCM0267  AC147 HCT 116 C190(1.03); C246(1.08); C69(1.22)  LDD0584  [11]
 LDCM0268  AC148 HCT 116 C190(1.08); C246(1.18); C69(1.70)  LDD0585  [11]
 LDCM0269  AC149 HCT 116 C190(1.09); C246(1.13); C69(1.44)  LDD0586  [11]
 LDCM0270  AC15 HCT 116 C190(0.99); C69(1.24)  LDD0587  [11]
 LDCM0271  AC150 HCT 116 C246(1.00); C190(1.04); C69(1.14)  LDD0588  [11]
 LDCM0272  AC151 HCT 116 C246(0.96); C190(0.97); C69(1.02)  LDD0589  [11]
 LDCM0273  AC152 HCT 116 C246(1.12); C190(1.16); C69(1.19)  LDD0590  [11]
 LDCM0274  AC153 HCT 116 C246(1.30); C190(1.48); C69(1.58)  LDD0591  [11]
 LDCM0621  AC154 HCT 116 C190(1.06); C246(1.04); C69(1.12)  LDD2158  [11]
 LDCM0622  AC155 HCT 116 C190(1.13); C246(1.04); C69(1.14)  LDD2159  [11]
 LDCM0623  AC156 HCT 116 C190(0.99); C246(0.98); C69(0.97)  LDD2160  [11]
 LDCM0624  AC157 HCT 116 C190(0.99); C246(1.60); C69(0.96)  LDD2161  [11]
 LDCM0276  AC17 HCT 116 C246(0.88); C190(0.97); C69(1.07)  LDD0593  [11]
 LDCM0277  AC18 HCT 116 C246(0.63); C190(1.02); C69(1.40)  LDD0594  [11]
 LDCM0278  AC19 HCT 116 C246(0.86); C190(0.93); C69(1.13)  LDD0595  [11]
 LDCM0279  AC2 HCT 116 C190(0.89); C69(1.15)  LDD0596  [11]
 LDCM0280  AC20 HCT 116 C246(0.91); C190(0.95); C69(1.07)  LDD0597  [11]
 LDCM0281  AC21 HCT 116 C246(0.84); C190(0.99); C69(1.12)  LDD0598  [11]
 LDCM0282  AC22 HCT 116 C246(0.85); C190(1.00); C69(1.08)  LDD0599  [11]
 LDCM0283  AC23 HCT 116 C246(0.84); C190(0.96); C69(1.17)  LDD0600  [11]
 LDCM0284  AC24 HCT 116 C246(0.98); C69(1.03); C190(1.05)  LDD0601  [11]
 LDCM0285  AC25 HCT 116 C246(0.91); C190(1.02); C69(1.05)  LDD0602  [11]
 LDCM0286  AC26 HCT 116 C246(0.80); C190(0.95); C69(1.14)  LDD0603  [11]
 LDCM0287  AC27 HCT 116 C190(0.93); C246(1.05); C69(1.15)  LDD0604  [11]
 LDCM0288  AC28 HCT 116 C246(0.87); C190(0.99); C69(1.11)  LDD0605  [11]
 LDCM0289  AC29 HCT 116 C190(0.89); C246(0.90); C69(1.16)  LDD0606  [11]
 LDCM0290  AC3 HCT 116 C190(0.88); C69(1.13)  LDD0607  [11]
 LDCM0291  AC30 HCT 116 C246(0.78); C190(0.84); C69(1.24)  LDD0608  [11]
 LDCM0292  AC31 HCT 116 C190(0.89); C246(0.89); C69(1.15)  LDD0609  [11]
 LDCM0293  AC32 HCT 116 C246(0.81); C190(0.94); C69(1.34)  LDD0610  [11]
 LDCM0294  AC33 HCT 116 C246(0.82); C190(0.97); C69(1.20)  LDD0611  [11]
 LDCM0295  AC34 HCT 116 C246(0.88); C190(0.98); C69(1.33)  LDD0612  [11]
 LDCM0296  AC35 HCT 116 C69(0.92); C190(1.11)  LDD0613  [11]
 LDCM0297  AC36 HCT 116 C69(0.93); C190(1.08)  LDD0614  [11]
 LDCM0298  AC37 HCT 116 C69(0.95); C190(1.16)  LDD0615  [11]
 LDCM0299  AC38 HCT 116 C69(0.95); C190(1.11)  LDD0616  [11]
 LDCM0300  AC39 HCT 116 C69(1.07); C190(1.11)  LDD0617  [11]
 LDCM0301  AC4 HCT 116 C190(1.03); C69(1.25)  LDD0618  [11]
 LDCM0302  AC40 HCT 116 C69(1.06); C190(1.08)  LDD0619  [11]
 LDCM0303  AC41 HCT 116 C190(1.02); C69(1.02)  LDD0620  [11]
 LDCM0304  AC42 HCT 116 C69(1.06); C190(1.11)  LDD0621  [11]
 LDCM0305  AC43 HCT 116 C190(1.06); C69(1.08)  LDD0622  [11]
 LDCM0306  AC44 HCT 116 C69(1.08); C190(1.18)  LDD0623  [11]
 LDCM0307  AC45 HCT 116 C69(1.17); C190(1.25)  LDD0624  [11]
 LDCM0308  AC46 HCT 116 C190(0.90); C69(1.17)  LDD0625  [11]
 LDCM0309  AC47 HCT 116 C190(0.97); C69(1.13)  LDD0626  [11]
 LDCM0310  AC48 HCT 116 C190(0.83); C69(1.15)  LDD0627  [11]
 LDCM0311  AC49 HCT 116 C190(1.11); C69(1.35)  LDD0628  [11]
 LDCM0312  AC5 HCT 116 C190(1.16); C69(1.27)  LDD0629  [11]
 LDCM0313  AC50 HCT 116 C190(0.96); C69(1.31)  LDD0630  [11]
 LDCM0314  AC51 HCT 116 C190(0.86); C69(1.00)  LDD0631  [11]
 LDCM0315  AC52 HCT 116 C190(0.91); C69(1.07)  LDD0632  [11]
 LDCM0316  AC53 HCT 116 C190(0.98); C69(1.22)  LDD0633  [11]
 LDCM0317  AC54 HCT 116 C190(1.01); C69(1.18)  LDD0634  [11]
 LDCM0318  AC55 HCT 116 C190(0.95); C69(1.31)  LDD0635  [11]
 LDCM0319  AC56 HCT 116 C190(1.06); C69(1.56)  LDD0636  [11]
 LDCM0320  AC57 HCT 116 C190(1.03); C69(1.24)  LDD0637  [11]
 LDCM0321  AC58 HCT 116 C190(1.06); C69(1.27)  LDD0638  [11]
 LDCM0322  AC59 HCT 116 C190(1.07); C69(1.32)  LDD0639  [11]
 LDCM0323  AC6 HCT 116 C190(0.92); C69(1.27)  LDD0640  [11]
 LDCM0324  AC60 HCT 116 C190(1.04); C69(1.29)  LDD0641  [11]
 LDCM0325  AC61 HCT 116 C190(0.95); C69(1.24)  LDD0642  [11]
 LDCM0326  AC62 HCT 116 C190(1.02); C69(1.39)  LDD0643  [11]
 LDCM0327  AC63 HCT 116 C190(1.11); C69(1.27)  LDD0644  [11]
 LDCM0328  AC64 HCT 116 C190(1.21); C69(1.44)  LDD0645  [11]
 LDCM0329  AC65 HCT 116 C190(0.98); C69(1.47)  LDD0646  [11]
 LDCM0330  AC66 HCT 116 C190(0.93); C69(1.37)  LDD0647  [11]
 LDCM0331  AC67 HCT 116 C190(0.96); C69(1.60)  LDD0648  [11]
 LDCM0332  AC68 HCT 116 C190(1.10); C69(1.28)  LDD0649  [11]
 LDCM0333  AC69 HCT 116 C190(1.12); C69(1.22)  LDD0650  [11]
 LDCM0334  AC7 HCT 116 C190(0.94); C69(1.18)  LDD0651  [11]
 LDCM0335  AC70 HCT 116 C69(1.22); C190(1.25)  LDD0652  [11]
 LDCM0336  AC71 HCT 116 C69(1.12); C190(1.16)  LDD0653  [11]
 LDCM0337  AC72 HCT 116 C190(1.16); C69(1.40)  LDD0654  [11]
 LDCM0338  AC73 HCT 116 C190(1.29); C69(1.63)  LDD0655  [11]
 LDCM0339  AC74 HCT 116 C190(1.27); C69(1.63)  LDD0656  [11]
 LDCM0340  AC75 HCT 116 C190(1.32); C69(2.12)  LDD0657  [11]
 LDCM0341  AC76 HCT 116 C190(1.16); C69(1.46)  LDD0658  [11]
 LDCM0342  AC77 HCT 116 C190(1.08); C69(1.24)  LDD0659  [11]
 LDCM0343  AC78 HCT 116 C190(1.07); C69(1.26)  LDD0660  [11]
 LDCM0344  AC79 HCT 116 C190(1.19); C69(1.26)  LDD0661  [11]
 LDCM0345  AC8 HCT 116 C190(0.88); C69(1.28)  LDD0662  [11]
 LDCM0346  AC80 HCT 116 C190(1.26); C69(1.29)  LDD0663  [11]
 LDCM0347  AC81 HCT 116 C190(1.05); C69(1.15)  LDD0664  [11]
 LDCM0348  AC82 HCT 116 C190(1.62); C69(2.22)  LDD0665  [11]
 LDCM0349  AC83 HCT 116 C190(1.15); C69(1.65)  LDD0666  [11]
 LDCM0350  AC84 HCT 116 C190(1.11); C69(1.51)  LDD0667  [11]
 LDCM0351  AC85 HCT 116 C190(1.05); C69(1.33)  LDD0668  [11]
 LDCM0352  AC86 HCT 116 C190(1.03); C69(1.20)  LDD0669  [11]
 LDCM0353  AC87 HCT 116 C190(0.94); C69(1.06)  LDD0670  [11]
 LDCM0354  AC88 HCT 116 C190(1.06); C69(1.18)  LDD0671  [11]
 LDCM0355  AC89 HCT 116 C190(0.95); C69(1.29)  LDD0672  [11]
 LDCM0357  AC90 HCT 116 C69(0.99); C190(1.05)  LDD0674  [11]
 LDCM0358  AC91 HCT 116 C190(1.16); C69(1.55)  LDD0675  [11]
 LDCM0359  AC92 HCT 116 C190(1.15); C69(1.51)  LDD0676  [11]
 LDCM0360  AC93 HCT 116 C190(1.06); C69(1.23)  LDD0677  [11]
 LDCM0361  AC94 HCT 116 C69(1.22); C190(1.23)  LDD0678  [11]
 LDCM0362  AC95 HCT 116 C190(0.92); C69(1.14)  LDD0679  [11]
 LDCM0363  AC96 HCT 116 C190(1.10); C69(1.24)  LDD0680  [11]
 LDCM0364  AC97 HCT 116 C190(1.11); C69(1.50)  LDD0681  [11]
 LDCM0365  AC98 HCT 116 C190(0.79); C69(1.53)  LDD0682  [11]
 LDCM0366  AC99 HCT 116 C190(0.84); C69(0.99)  LDD0683  [11]
 LDCM0248  AKOS034007472 HCT 116 C190(0.91); C69(1.09)  LDD0565  [11]
 LDCM0356  AKOS034007680 HCT 116 C190(0.98); C69(1.18)  LDD0673  [11]
 LDCM0275  AKOS034007705 HCT 116 C190(0.97); C69(1.69)  LDD0592  [11]
 LDCM0156  Aniline NCI-H1299 11.62  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C69(1.02)  LDD2171  [11]
 LDCM0498  BS-3668 MDA-MB-231 C69(0.55); C190(0.60)  LDD2091  [6]
 LDCM0630  CCW28-3 231MFP C69(1.38)  LDD2214  [26]
 LDCM0108  Chloroacetamide HeLa C69(0.00); C246(0.00); H189(0.00); H207(0.00)  LDD0222  [10]
 LDCM0632  CL-Sc Hep-G2 C69(1.15); C246(0.98); C225(0.85); C190(0.32)  LDD2227  [16]
 LDCM0367  CL1 HCT 116 C69(0.91); C246(0.97); C190(1.05)  LDD0684  [11]
 LDCM0368  CL10 HCT 116 C190(0.99); C246(1.05); C69(1.39)  LDD0685  [11]
 LDCM0369  CL100 HCT 116 C190(0.88); C69(1.29)  LDD0686  [11]
 LDCM0370  CL101 HCT 116 C190(0.88); C69(1.15)  LDD0687  [11]
 LDCM0371  CL102 HCT 116 C190(0.93); C69(1.02)  LDD0688  [11]
 LDCM0372  CL103 HCT 116 C190(0.82); C69(1.05)  LDD0689  [11]
 LDCM0373  CL104 HCT 116 C190(0.86); C69(1.00)  LDD0690  [11]
 LDCM0374  CL105 HCT 116 C246(0.68); C190(1.04); C69(1.21)  LDD0691  [11]
 LDCM0375  CL106 HCT 116 C246(0.82); C190(0.97); C69(1.52)  LDD0692  [11]
 LDCM0376  CL107 HCT 116 C246(0.78); C190(1.03); C69(1.44)  LDD0693  [11]
 LDCM0377  CL108 HCT 116 C246(0.73); C190(1.13); C69(1.40)  LDD0694  [11]
 LDCM0378  CL109 HCT 116 C246(0.92); C190(0.98); C69(1.23)  LDD0695  [11]
 LDCM0379  CL11 HCT 116 C190(1.02); C246(1.05); C69(1.43)  LDD0696  [11]
 LDCM0380  CL110 HCT 116 C246(0.75); C190(1.02); C69(1.31)  LDD0697  [11]
 LDCM0381  CL111 HCT 116 C246(0.73); C190(1.02); C69(1.32)  LDD0698  [11]
 LDCM0382  CL112 HCT 116 C246(0.58); C190(1.00); C69(1.04)  LDD0699  [11]
 LDCM0383  CL113 HCT 116 C246(0.84); C190(0.96); C69(1.25)  LDD0700  [11]
 LDCM0384  CL114 HCT 116 C246(0.74); C190(0.89); C69(1.17)  LDD0701  [11]
 LDCM0385  CL115 HCT 116 C246(0.80); C190(0.91); C69(1.25)  LDD0702  [11]
 LDCM0386  CL116 HCT 116 C246(0.75); C190(0.98); C69(1.17)  LDD0703  [11]
 LDCM0387  CL117 HCT 116 C190(1.13); C69(1.31)  LDD0704  [11]
 LDCM0388  CL118 HCT 116 C69(1.05); C190(1.07)  LDD0705  [11]
 LDCM0389  CL119 HCT 116 C190(0.99); C69(1.06)  LDD0706  [11]
 LDCM0390  CL12 HCT 116 C190(1.14); C246(1.16); C69(1.34)  LDD0707  [11]
 LDCM0391  CL120 HCT 116 C69(0.98); C190(1.02)  LDD0708  [11]
 LDCM0392  CL121 HCT 116 C190(0.68); C69(1.01)  LDD0709  [11]
 LDCM0393  CL122 HCT 116 C190(0.96); C69(1.17)  LDD0710  [11]
 LDCM0394  CL123 HCT 116 C190(0.88); C69(1.23)  LDD0711  [11]
 LDCM0395  CL124 HCT 116 C190(1.00); C69(1.35)  LDD0712  [11]
 LDCM0396  CL125 HCT 116 C69(1.09); C190(1.09)  LDD0713  [11]
 LDCM0397  CL126 HCT 116 C190(0.95); C69(1.07)  LDD0714  [11]
 LDCM0398  CL127 HCT 116 C190(0.99); C69(1.15)  LDD0715  [11]
 LDCM0399  CL128 HCT 116 C190(1.03); C69(1.35)  LDD0716  [11]
 LDCM0400  CL13 HCT 116 C246(0.98); C190(1.04); C69(1.25)  LDD0717  [11]
 LDCM0401  CL14 HCT 116 C190(1.00); C246(1.01); C69(1.01)  LDD0718  [11]
 LDCM0402  CL15 HCT 116 C246(0.84); C190(1.06); C69(1.19)  LDD0719  [11]
 LDCM0403  CL16 HCT 116 C246(1.06); C69(1.07); C190(1.28)  LDD0720  [11]
 LDCM0404  CL17 HCT 116 C190(0.85); C69(1.03); C246(1.14)  LDD0721  [11]
 LDCM0405  CL18 HCT 116 C190(0.94); C69(1.11); C246(1.13)  LDD0722  [11]
 LDCM0406  CL19 HCT 116 C190(1.05); C246(1.07); C69(1.14)  LDD0723  [11]
 LDCM0407  CL2 HCT 116 C246(0.93); C190(0.95); C69(0.97)  LDD0724  [11]
 LDCM0408  CL20 HCT 116 C190(1.01); C69(1.24); C246(1.38)  LDD0725  [11]
 LDCM0409  CL21 HCT 116 C190(1.03); C246(1.17); C69(1.33)  LDD0726  [11]
 LDCM0410  CL22 HCT 116 C190(1.17); C246(1.25); C69(1.76)  LDD0727  [11]
 LDCM0411  CL23 HCT 116 C190(0.86); C246(1.21); C69(1.21)  LDD0728  [11]
 LDCM0412  CL24 HCT 116 C190(0.98); C246(1.32); C69(1.37)  LDD0729  [11]
 LDCM0413  CL25 HCT 116 C190(1.10); C246(1.05); C69(1.38)  LDD0730  [11]
 LDCM0414  CL26 HCT 116 C190(0.98); C246(1.21); C69(1.28)  LDD0731  [11]
 LDCM0415  CL27 HCT 116 C190(1.10); C246(1.09); C69(1.19)  LDD0732  [11]
 LDCM0416  CL28 HCT 116 C190(1.07); C246(1.03); C69(1.26)  LDD0733  [11]
 LDCM0417  CL29 HCT 116 C190(1.02); C246(1.19); C69(1.28)  LDD0734  [11]
 LDCM0418  CL3 HCT 116 C190(1.04); C246(0.92); C69(0.93)  LDD0735  [11]
 LDCM0419  CL30 HCT 116 C190(0.99); C246(1.04); C69(1.11)  LDD0736  [11]
 LDCM0420  CL31 HCT 116 C190(0.98); C246(1.00); C69(1.11)  LDD0737  [11]
 LDCM0421  CL32 HCT 116 C190(0.83); C246(1.20); C69(1.23)  LDD0738  [11]
 LDCM0422  CL33 HCT 116 C190(0.83); C246(1.37); C69(1.24)  LDD0739  [11]
 LDCM0423  CL34 HCT 116 C190(0.91); C246(1.00); C69(1.32)  LDD0740  [11]
 LDCM0424  CL35 HCT 116 C190(0.96); C246(1.27); C69(1.29)  LDD0741  [11]
 LDCM0425  CL36 HCT 116 C190(0.94); C246(1.10); C69(1.22)  LDD0742  [11]
 LDCM0426  CL37 HCT 116 C190(0.98); C246(1.93); C69(1.34)  LDD0743  [11]
 LDCM0428  CL39 HCT 116 C190(1.01); C246(1.00); C69(1.37)  LDD0745  [11]
 LDCM0429  CL4 HCT 116 C190(0.88); C246(0.96); C69(0.93)  LDD0746  [11]
 LDCM0430  CL40 HCT 116 C190(0.89); C246(1.34); C69(1.26)  LDD0747  [11]
 LDCM0431  CL41 HCT 116 C190(1.03); C246(1.37); C69(1.24)  LDD0748  [11]
 LDCM0432  CL42 HCT 116 C190(1.16); C246(1.26); C69(2.04)  LDD0749  [11]
 LDCM0433  CL43 HCT 116 C190(0.92); C246(1.21); C69(1.49)  LDD0750  [11]
 LDCM0434  CL44 HCT 116 C190(0.96); C246(1.33); C69(1.36)  LDD0751  [11]
 LDCM0435  CL45 HCT 116 C190(0.89); C246(1.30); C69(1.54)  LDD0752  [11]
 LDCM0436  CL46 HCT 116 C190(0.84); C69(0.88)  LDD0753  [11]
 LDCM0437  CL47 HCT 116 C190(0.84); C69(0.91)  LDD0754  [11]
 LDCM0438  CL48 HCT 116 C190(0.88); C69(0.89)  LDD0755  [11]
 LDCM0439  CL49 HCT 116 C190(1.03); C69(0.90)  LDD0756  [11]
 LDCM0440  CL5 HCT 116 C190(1.05); C246(1.01); C69(0.95)  LDD0757  [11]
 LDCM0441  CL50 HCT 116 C190(1.03); C69(0.86)  LDD0758  [11]
 LDCM0442  CL51 HCT 116 C190(0.95); C69(0.89)  LDD0759  [11]
 LDCM0443  CL52 HCT 116 C190(0.89); C69(0.92)  LDD0760  [11]
 LDCM0444  CL53 HCT 116 C190(0.98); C69(0.86)  LDD0761  [11]
 LDCM0445  CL54 HCT 116 C190(0.86); C69(0.85)  LDD0762  [11]
 LDCM0446  CL55 HCT 116 C190(0.96); C69(0.83)  LDD0763  [11]
 LDCM0447  CL56 HCT 116 C190(0.97); C69(0.99)  LDD0764  [11]
 LDCM0448  CL57 HCT 116 C190(0.97); C69(0.85)  LDD0765  [11]
 LDCM0449  CL58 HCT 116 C190(0.82); C69(0.83)  LDD0766  [11]
 LDCM0450  CL59 HCT 116 C190(1.00); C69(0.93)  LDD0767  [11]
 LDCM0451  CL6 HCT 116 C190(1.01); C246(0.76); C69(1.01)  LDD0768  [11]
 LDCM0452  CL60 HCT 116 C190(0.96); C69(0.96)  LDD0769  [11]
 LDCM0453  CL61 HCT 116 C190(0.98); C246(1.08); C69(1.07)  LDD0770  [11]
 LDCM0454  CL62 HCT 116 C190(1.08); C246(0.92); C69(1.32)  LDD0771  [11]
 LDCM0455  CL63 HCT 116 C190(1.11); C246(0.83); C69(1.21)  LDD0772  [11]
 LDCM0456  CL64 HCT 116 C190(0.99); C246(0.98); C69(1.27)  LDD0773  [11]
 LDCM0457  CL65 HCT 116 C190(1.08); C246(0.85); C69(1.13)  LDD0774  [11]
 LDCM0458  CL66 HCT 116 C190(1.15); C246(0.91); C69(1.62)  LDD0775  [11]
 LDCM0459  CL67 HCT 116 C190(1.22); C246(0.84); C69(1.34)  LDD0776  [11]
 LDCM0460  CL68 HCT 116 C190(1.05); C246(0.77); C69(1.31)  LDD0777  [11]
 LDCM0461  CL69 HCT 116 C190(0.92); C246(1.01); C69(1.16)  LDD0778  [11]
 LDCM0462  CL7 HCT 116 C190(1.03); C246(0.93); C69(1.14)  LDD0779  [11]
 LDCM0463  CL70 HCT 116 C190(0.95); C246(0.88); C69(1.36)  LDD0780  [11]
 LDCM0464  CL71 HCT 116 C190(1.07); C246(0.78); C69(1.39)  LDD0781  [11]
 LDCM0465  CL72 HCT 116 C190(1.11); C246(0.73); C69(1.24)  LDD0782  [11]
 LDCM0466  CL73 HCT 116 C190(1.08); C246(0.91); C69(1.31)  LDD0783  [11]
 LDCM0467  CL74 HCT 116 C190(1.04); C246(0.90); C69(1.35)  LDD0784  [11]
 LDCM0469  CL76 HCT 116 C190(1.15); C69(1.11)  LDD0786  [11]
 LDCM0470  CL77 HCT 116 C190(1.02); C69(1.06)  LDD0787  [11]
 LDCM0471  CL78 HCT 116 C190(0.99); C69(1.21)  LDD0788  [11]
 LDCM0472  CL79 HCT 116 C190(1.04); C69(1.32)  LDD0789  [11]
 LDCM0473  CL8 HCT 116 C190(1.09); C246(1.14); C69(1.53)  LDD0790  [11]
 LDCM0474  CL80 HCT 116 C190(1.20); C69(1.12)  LDD0791  [11]
 LDCM0475  CL81 HCT 116 C190(1.24); C69(1.15)  LDD0792  [11]
 LDCM0476  CL82 HCT 116 C190(1.15); C69(1.48)  LDD0793  [11]
 LDCM0477  CL83 HCT 116 C190(1.10); C69(1.54)  LDD0794  [11]
 LDCM0478  CL84 HCT 116 C190(1.13); C69(1.79)  LDD0795  [11]
 LDCM0479  CL85 HCT 116 C190(1.02); C69(1.29)  LDD0796  [11]
 LDCM0480  CL86 HCT 116 C190(1.11); C69(1.09)  LDD0797  [11]
 LDCM0481  CL87 HCT 116 C190(1.10); C69(1.28)  LDD0798  [11]
 LDCM0482  CL88 HCT 116 C190(1.14); C69(1.53)  LDD0799  [11]
 LDCM0483  CL89 HCT 116 C190(1.09); C69(2.19)  LDD0800  [11]
 LDCM0484  CL9 HCT 116 C190(1.12); C246(1.14); C69(1.12)  LDD0801  [11]
 LDCM0485  CL90 HCT 116 C190(1.05); C69(1.08)  LDD0802  [11]
 LDCM0486  CL91 HCT 116 C190(0.83); C69(1.19)  LDD0803  [11]
 LDCM0487  CL92 HCT 116 C190(0.94); C69(1.11)  LDD0804  [11]
 LDCM0488  CL93 HCT 116 C190(0.91); C69(1.07)  LDD0805  [11]
 LDCM0489  CL94 HCT 116 C190(1.11); C69(1.13)  LDD0806  [11]
 LDCM0490  CL95 HCT 116 C190(1.01); C69(1.28)  LDD0807  [11]
 LDCM0491  CL96 HCT 116 C190(0.89); C69(1.10)  LDD0808  [11]
 LDCM0492  CL97 HCT 116 C190(0.82); C69(1.16)  LDD0809  [11]
 LDCM0493  CL98 HCT 116 C190(0.99); C69(1.26)  LDD0810  [11]
 LDCM0494  CL99 HCT 116 C190(0.89); C69(1.24)  LDD0811  [11]
 LDCM0495  E2913 HEK-293T C190(1.04); C69(0.84); C246(0.96); C168(1.15)  LDD1698  [27]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C190(2.59); C69(1.26)  LDD1702  [6]
 LDCM0625  F8 Ramos C69(1.53); C246(0.80)  LDD2187  [28]
 LDCM0572  Fragment10 Ramos C69(0.99); C246(0.61)  LDD2189  [28]
 LDCM0573  Fragment11 Ramos C69(0.61); C246(6.25)  LDD2190  [28]
 LDCM0574  Fragment12 Ramos C69(0.63)  LDD2191  [28]
 LDCM0575  Fragment13 Ramos C69(0.98); C246(0.26)  LDD2192  [28]
 LDCM0576  Fragment14 Ramos C69(0.71); C246(0.80)  LDD2193  [28]
 LDCM0579  Fragment20 Ramos C69(0.64); C246(0.69)  LDD2194  [28]
 LDCM0580  Fragment21 Ramos C69(1.27); C246(0.51)  LDD2195  [28]
 LDCM0582  Fragment23 Ramos C69(1.17); C246(0.77)  LDD2196  [28]
 LDCM0578  Fragment27 Ramos C69(1.38); C246(1.01)  LDD2197  [28]
 LDCM0586  Fragment28 Ramos C69(0.49); C246(0.72)  LDD2198  [28]
 LDCM0588  Fragment30 Ramos C69(1.13); C246(0.18)  LDD2199  [28]
 LDCM0589  Fragment31 Ramos C69(0.98)  LDD2200  [28]
 LDCM0590  Fragment32 Ramos C69(0.67)  LDD2201  [28]
 LDCM0468  Fragment33 HCT 116 C190(1.00); C246(0.73); C69(1.37)  LDD0785  [11]
 LDCM0596  Fragment38 Ramos C69(0.78); C246(0.88)  LDD2203  [28]
 LDCM0566  Fragment4 Ramos C69(1.12); C246(0.57)  LDD2184  [28]
 LDCM0427  Fragment51 HCT 116 C190(1.02); C246(0.86); C69(1.73)  LDD0744  [11]
 LDCM0610  Fragment52 Ramos C69(1.03); C246(0.56)  LDD2204  [28]
 LDCM0614  Fragment56 Ramos C69(1.51); C246(0.36)  LDD2205  [28]
 LDCM0569  Fragment7 Ramos C69(1.50); C246(0.74)  LDD2186  [28]
 LDCM0571  Fragment9 Ramos C69(0.71)  LDD2188  [28]
 LDCM0116  HHS-0101 DM93 Y714(0.60); Y897(0.61)  LDD0264  [8]
 LDCM0117  HHS-0201 DM93 Y897(0.73)  LDD0265  [8]
 LDCM0118  HHS-0301 DM93 Y897(0.69)  LDD0266  [8]
 LDCM0119  HHS-0401 DM93 Y897(0.54)  LDD0267  [8]
 LDCM0120  HHS-0701 DM93 Y897(0.45); Y714(4.81)  LDD0268  [8]
 LDCM0107  IAA HeLa N.A.  LDD0221  [10]
 LDCM0179  JZ128 PC-3 N.A.  LDD0462  [5]
 LDCM0022  KB02 HCT 116 C246(2.21); C69(1.52)  LDD0080  [11]
 LDCM0023  KB03 HCT 116 C246(4.71); C69(1.09)  LDD0081  [11]
 LDCM0024  KB05 HCT 116 C246(3.29); C69(1.58)  LDD0082  [11]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C69(0.94)  LDD2102  [6]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C69(0.76)  LDD2121  [6]
 LDCM0109  NEM HeLa N.A.  LDD0223  [10]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C69(1.18)  LDD2090  [6]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C190(0.83)  LDD2092  [6]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C69(1.03); C190(0.97)  LDD2094  [6]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C69(0.43)  LDD2098  [6]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C69(0.94)  LDD2099  [6]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C69(0.94)  LDD2100  [6]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C69(0.60)  LDD2101  [6]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C69(0.79)  LDD2104  [6]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C69(1.27); C190(1.16)  LDD2105  [6]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C69(0.92); C190(0.95)  LDD2106  [6]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C190(1.02)  LDD2107  [6]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C69(0.71); C190(0.84)  LDD2108  [6]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C69(0.73); C190(1.46); C915(1.80)  LDD2109  [6]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C190(1.00)  LDD2111  [6]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C69(1.21); C190(0.91)  LDD2114  [6]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C69(1.01)  LDD2118  [6]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C69(2.89); C190(1.54)  LDD2119  [6]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C69(0.88)  LDD2120  [6]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C69(0.16)  LDD2122  [6]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C69(0.92); C190(1.11)  LDD2123  [6]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C69(0.21)  LDD2124  [6]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C69(0.80); C190(1.19)  LDD2125  [6]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C69(0.16)  LDD2126  [6]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C69(0.95); C190(1.60)  LDD2127  [6]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C190(1.12)  LDD2129  [6]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C69(1.01)  LDD2135  [6]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C69(1.15)  LDD2136  [6]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C69(0.86); C190(1.31)  LDD2137  [6]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C69(1.03); C190(1.20)  LDD2140  [6]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C69(0.56)  LDD2141  [6]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C69(1.01); C915(1.06)  LDD2143  [6]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C69(0.88); C190(1.06)  LDD2146  [6]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C69(1.79)  LDD2147  [6]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C69(0.83)  LDD2149  [6]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C69(0.47)  LDD2150  [6]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C69(1.95)  LDD2153  [6]
 LDCM0627  NUDT7-COV-1 HEK-293T C69(0.28)  LDD2206  [29]
 LDCM0628  OTUB2-COV-1 HEK-293T C69(0.28)  LDD2207  [29]
 LDCM0131  RA190 MM1.R C69(1.46)  LDD0304  [30]
 LDCM0021  THZ1 HCT 116 C69(1.02)  LDD2173  [11]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Fidgetin (FIGN) AAA ATPase family Q5HY92
ATP-dependent RNA helicase DHX8 (DHX8) DEAD box helicase family Q14562
Fas-activated serine/threonine kinase (FASTK) FAST protein kinase family Q14296
Dual specificity protein kinase CLK3 (CLK3) CMGC Ser/Thr protein kinase family P49761
Protein FRA10AC1 (FRA10AC1) . Q70Z53
Other
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Splicing factor 1 (SF1) BBP/SF1 family Q15637
Stabilizer of axonemal microtubules 1 (SAXO1) FAM154 family Q8IYX7
Putative RNA-binding protein Luc7-like 1 (LUC7L) Luc7 family Q9NQ29
Keratin-associated protein 11-1 (KRTAP11-1) PMG family Q8IUC1
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (SNRNP27) SNUT3 family Q8WVK2
Splicing factor U2AF 65 kDa subunit (U2AF2) Splicing factor SR family P26368
Melanoma-associated antigen D1 (MAGED1) . Q9Y5V3
Uncharacterized protein C1orf94 (C1orf94) . Q6P1W5
Vinexin (SORBS3) . O60504

References

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2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
4 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
5 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.
6 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
7 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
8 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
9 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
10 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
11 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
12 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
13 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
14 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647
15 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
16 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
17 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
18 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
19 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
20 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
21 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
22 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
23 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
24 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
25 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
26 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
27 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
28 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
29 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.
30 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.