General Information of Target

Target ID LDTP01556
Target Name Vesicle-associated membrane protein-associated protein B/C (VAPB)
Gene Name VAPB
Gene ID 9217
Synonyms
Vesicle-associated membrane protein-associated protein B/C; VAMP-B/VAMP-C; VAMP-associated protein B/C; VAP-B/VAP-C
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI
IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR
CVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEV
QRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIGK
IAL
Target Bioclass
Transporter and channel
Family
VAMP-associated protein (VAP) (TC 9.B.17) family
Subcellular location
Endoplasmic reticulum membrane
Function
Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44. Interacts with STARD3 in a FFAT motif phosphorylation dependent manner. Via interaction with WDR44 participates in neosynthesized protein export. Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.
Uniprot ID
O95292
Ensemble ID
ENST00000395802.7
HGNC ID
HGNC:12649

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 27 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info 
15.00  LDD0402  [1]
YN-1
 Probe Info 
100.00  LDD0444  [2]
ONAyne
 Probe Info 
K118(1.01)  LDD0274  [3]
STPyne
 Probe Info 
K118(6.13)  LDD0277  [3]
OPA-S-S-alkyne
 Probe Info 
K174(1.61); K45(4.46)  LDD3494  [4]
BTD
 Probe Info 
C173(1.38)  LDD2090  [5]
DA-P3
 Probe Info 
4.85  LDD0181  [6]
AHL-Pu-1
 Probe Info 
C173(2.72)  LDD0171  [7]
Alkyne-RA190
 Probe Info 
3.33  LDD0300  [8]
DBIA
 Probe Info 
C121(0.60)  LDD0533  [9]
5E-2FA
 Probe Info 
N.A.  LDD2235  [10]
ATP probe
 Probe Info 
N.A.  LDD0199  [11]
IA-alkyne
 Probe Info 
N.A.  LDD0032  [12]
Lodoacetamide azide
 Probe Info 
C121(0.00); C173(0.00)  LDD0037  [13]
JW-RF-010
 Probe Info 
N.A.  LDD0026  [14]
TFBX
 Probe Info 
N.A.  LDD0027  [14]
IPM
 Probe Info 
N.A.  LDD0005  [15]
NHS
 Probe Info 
K3(0.00); K167(0.00); K168(0.00); K118(0.00)  LDD0010  [15]
Phosphinate-6
 Probe Info 
C53(0.00); C173(0.00)  LDD0018  [16]
1c-yne
 Probe Info 
N.A.  LDD0228  [17]
Acrolein
 Probe Info 
H14(0.00); C173(0.00); C121(0.00)  LDD0217  [18]
Crotonaldehyde
 Probe Info 
N.A.  LDD0219  [18]
Methacrolein
 Probe Info 
N.A.  LDD0218  [18]
W1
 Probe Info 
N.A.  LDD0236  [19]
AOyne
 Probe Info 
14.80  LDD0443  [20]
NAIA_5
 Probe Info 
C121(0.00); C173(0.00); C41(0.00)  LDD2223  [21]
TPP-AC
 Probe Info 
N.A.  LDD0427  [22]
PAL-AfBPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe13
 Probe Info 
20.00  LDD0475  [23]
FFF probe14
 Probe Info 
20.00  LDD0477  [23]
FFF probe2
 Probe Info 
15.03  LDD0463  [23]
FFF probe3
 Probe Info 
20.00  LDD0464  [23]
OEA-DA
 Probe Info 
4.57  LDD0046  [24]
STS-1
 Probe Info 
N.A.  LDD0068  [25]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C173(0.71); C121(0.84)  LDD2142  [5]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C173(0.87)  LDD2112  [5]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C173(1.55); C121(1.48)  LDD2117  [5]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C173(1.33)  LDD2103  [5]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C121(0.91)  LDD2132  [5]
 LDCM0025  4SU-RNA HEK-293T C53(2.16)  LDD0371  [7]
 LDCM0026  4SU-RNA+native RNA DM93 C173(2.72)  LDD0171  [7]
 LDCM0214  AC1 PaTu 8988t C121(0.57)  LDD1093  [9]
 LDCM0215  AC10 PaTu 8988t C121(0.41)  LDD1094  [9]
 LDCM0216  AC100 HCT 116 C121(0.60)  LDD0533  [9]
 LDCM0217  AC101 HCT 116 C121(0.61)  LDD0534  [9]
 LDCM0218  AC102 HCT 116 C121(0.65)  LDD0535  [9]
 LDCM0219  AC103 HCT 116 C121(0.53)  LDD0536  [9]
 LDCM0220  AC104 HCT 116 C121(0.82)  LDD0537  [9]
 LDCM0221  AC105 HCT 116 C121(0.69)  LDD0538  [9]
 LDCM0222  AC106 HCT 116 C121(0.60)  LDD0539  [9]
 LDCM0223  AC107 HCT 116 C121(0.63)  LDD0540  [9]
 LDCM0224  AC108 HCT 116 C121(0.56)  LDD0541  [9]
 LDCM0225  AC109 HCT 116 C121(0.84)  LDD0542  [9]
 LDCM0226  AC11 PaTu 8988t C121(0.79)  LDD1105  [9]
 LDCM0227  AC110 HCT 116 C121(0.50)  LDD0544  [9]
 LDCM0228  AC111 HCT 116 C121(0.50)  LDD0545  [9]
 LDCM0229  AC112 HCT 116 C121(0.52)  LDD0546  [9]
 LDCM0230  AC113 HCT 116 C121(0.36)  LDD0547  [9]
 LDCM0231  AC114 HCT 116 C121(0.35)  LDD0548  [9]
 LDCM0232  AC115 HCT 116 C121(0.41)  LDD0549  [9]
 LDCM0233  AC116 HCT 116 C121(0.47)  LDD0550  [9]
 LDCM0234  AC117 HCT 116 C121(0.48)  LDD0551  [9]
 LDCM0235  AC118 HCT 116 C121(0.40)  LDD0552  [9]
 LDCM0236  AC119 HCT 116 C121(0.35)  LDD0553  [9]
 LDCM0237  AC12 PaTu 8988t C121(0.66)  LDD1116  [9]
 LDCM0238  AC120 HCT 116 C121(0.48)  LDD0555  [9]
 LDCM0239  AC121 HCT 116 C121(0.30)  LDD0556  [9]
 LDCM0240  AC122 HCT 116 C121(0.34)  LDD0557  [9]
 LDCM0241  AC123 HCT 116 C121(0.32)  LDD0558  [9]
 LDCM0242  AC124 HCT 116 C121(0.32)  LDD0559  [9]
 LDCM0243  AC125 HCT 116 C121(0.47)  LDD0560  [9]
 LDCM0244  AC126 HCT 116 C121(0.44)  LDD0561  [9]
 LDCM0245  AC127 HCT 116 C121(0.33)  LDD0562  [9]
 LDCM0246  AC128 HCT 116 C121(0.65)  LDD0563  [9]
 LDCM0247  AC129 HCT 116 C121(0.68)  LDD0564  [9]
 LDCM0249  AC130 HCT 116 C121(0.52)  LDD0566  [9]
 LDCM0250  AC131 HCT 116 C121(0.53)  LDD0567  [9]
 LDCM0251  AC132 HCT 116 C121(0.80)  LDD0568  [9]
 LDCM0252  AC133 HCT 116 C121(0.57)  LDD0569  [9]
 LDCM0253  AC134 HCT 116 C121(0.55)  LDD0570  [9]
 LDCM0254  AC135 HCT 116 C121(0.57)  LDD0571  [9]
 LDCM0255  AC136 HCT 116 C121(0.57)  LDD0572  [9]
 LDCM0256  AC137 HCT 116 C121(0.55)  LDD0573  [9]
 LDCM0257  AC138 HCT 116 C121(0.46)  LDD0574  [9]
 LDCM0258  AC139 HCT 116 C121(0.54)  LDD0575  [9]
 LDCM0259  AC14 PaTu 8988t C121(0.70)  LDD1138  [9]
 LDCM0260  AC140 HCT 116 C121(0.49)  LDD0577  [9]
 LDCM0261  AC141 HCT 116 C121(0.55)  LDD0578  [9]
 LDCM0262  AC142 HCT 116 C121(0.56)  LDD0579  [9]
 LDCM0263  AC143 HCT 116 C121(0.87)  LDD0580  [9]
 LDCM0264  AC144 HCT 116 C121(0.76)  LDD0581  [9]
 LDCM0265  AC145 HCT 116 C121(0.87)  LDD0582  [9]
 LDCM0266  AC146 HCT 116 C121(0.63)  LDD0583  [9]
 LDCM0267  AC147 HCT 116 C121(0.86)  LDD0584  [9]
 LDCM0268  AC148 HCT 116 C121(0.55)  LDD0585  [9]
 LDCM0269  AC149 HCT 116 C121(0.68)  LDD0586  [9]
 LDCM0270  AC15 PaTu 8988t C121(0.46)  LDD1149  [9]
 LDCM0271  AC150 HCT 116 C121(1.00)  LDD0588  [9]
 LDCM0272  AC151 HCT 116 C121(0.76)  LDD0589  [9]
 LDCM0273  AC152 HCT 116 C121(0.72)  LDD0590  [9]
 LDCM0274  AC153 HCT 116 C121(0.55)  LDD0591  [9]
 LDCM0621  AC154 HCT 116 C121(0.81)  LDD2158  [9]
 LDCM0622  AC155 HCT 116 C121(0.71)  LDD2159  [9]
 LDCM0623  AC156 HCT 116 C121(0.89)  LDD2160  [9]
 LDCM0624  AC157 HCT 116 C121(0.89)  LDD2161  [9]
 LDCM0276  AC17 PaTu 8988t C121(1.23)  LDD1155  [9]
 LDCM0277  AC18 PaTu 8988t C121(0.87)  LDD1156  [9]
 LDCM0278  AC19 PaTu 8988t C121(0.96)  LDD1157  [9]
 LDCM0279  AC2 PaTu 8988t C121(0.81)  LDD1158  [9]
 LDCM0280  AC20 PaTu 8988t C121(0.97)  LDD1159  [9]
 LDCM0281  AC21 PaTu 8988t C121(1.15)  LDD1160  [9]
 LDCM0282  AC22 PaTu 8988t C121(0.96)  LDD1161  [9]
 LDCM0283  AC23 PaTu 8988t C121(0.88)  LDD1162  [9]
 LDCM0284  AC24 PaTu 8988t C121(0.90)  LDD1163  [9]
 LDCM0285  AC25 HEK-293T C173(1.33); C121(0.98); C53(1.06)  LDD1524  [26]
 LDCM0286  AC26 HEK-293T C173(1.42); C121(1.02); C53(0.98)  LDD1525  [26]
 LDCM0287  AC27 HEK-293T C173(1.16); C121(1.14); C53(0.96)  LDD1526  [26]
 LDCM0288  AC28 HEK-293T C173(1.52); C121(1.10); C53(1.13)  LDD1527  [26]
 LDCM0289  AC29 HEK-293T C173(1.15); C121(1.02); C53(0.89)  LDD1528  [26]
 LDCM0290  AC3 PaTu 8988t C121(0.79)  LDD1169  [9]
 LDCM0291  AC30 HEK-293T C173(1.28); C121(1.25); C53(1.14)  LDD1530  [26]
 LDCM0292  AC31 HEK-293T C173(1.10); C121(1.08); C53(1.02)  LDD1531  [26]
 LDCM0293  AC32 HEK-293T C173(1.04); C121(1.03); C53(1.11)  LDD1532  [26]
 LDCM0294  AC33 HEK-293T C173(1.29); C121(1.02); C53(1.13)  LDD1533  [26]
 LDCM0295  AC34 HEK-293T C173(1.35); C121(1.02); C53(1.09)  LDD1534  [26]
 LDCM0296  AC35 PaTu 8988t C121(0.59)  LDD1175  [9]
 LDCM0297  AC36 PaTu 8988t C121(0.46)  LDD1176  [9]
 LDCM0298  AC37 PaTu 8988t C121(0.83)  LDD1177  [9]
 LDCM0299  AC38 PaTu 8988t C121(0.55)  LDD1178  [9]
 LDCM0300  AC39 PaTu 8988t C121(0.54)  LDD1179  [9]
 LDCM0301  AC4 PaTu 8988t C121(0.71)  LDD1180  [9]
 LDCM0302  AC40 PaTu 8988t C121(0.54)  LDD1181  [9]
 LDCM0303  AC41 PaTu 8988t C121(0.98)  LDD1182  [9]
 LDCM0304  AC42 PaTu 8988t C121(0.95)  LDD1183  [9]
 LDCM0305  AC43 PaTu 8988t C121(1.00)  LDD1184  [9]
 LDCM0306  AC44 PaTu 8988t C121(0.93)  LDD1185  [9]
 LDCM0307  AC45 PaTu 8988t C121(0.84)  LDD1186  [9]
 LDCM0308  AC46 PaTu 8988t C121(0.52)  LDD1187  [9]
 LDCM0309  AC47 PaTu 8988t C121(0.67)  LDD1188  [9]
 LDCM0310  AC48 PaTu 8988t C121(0.65)  LDD1189  [9]
 LDCM0311  AC49 PaTu 8988t C121(0.54)  LDD1190  [9]
 LDCM0312  AC5 PaTu 8988t C121(0.76)  LDD1191  [9]
 LDCM0313  AC50 PaTu 8988t C121(0.56)  LDD1192  [9]
 LDCM0314  AC51 PaTu 8988t C121(0.17)  LDD1193  [9]
 LDCM0315  AC52 PaTu 8988t C121(0.67)  LDD1194  [9]
 LDCM0316  AC53 PaTu 8988t C121(0.54)  LDD1195  [9]
 LDCM0317  AC54 PaTu 8988t C121(0.59)  LDD1196  [9]
 LDCM0318  AC55 PaTu 8988t C121(0.39)  LDD1197  [9]
 LDCM0319  AC56 PaTu 8988t C121(0.30)  LDD1198  [9]
 LDCM0320  AC57 HCT 116 C121(0.71)  LDD0637  [9]
 LDCM0321  AC58 HCT 116 C121(1.17)  LDD0638  [9]
 LDCM0322  AC59 HCT 116 C121(0.66)  LDD0639  [9]
 LDCM0323  AC6 PaTu 8988t C121(0.82)  LDD1202  [9]
 LDCM0324  AC60 HCT 116 C121(0.64)  LDD0641  [9]
 LDCM0325  AC61 HCT 116 C121(0.56)  LDD0642  [9]
 LDCM0326  AC62 HCT 116 C121(0.68)  LDD0643  [9]
 LDCM0327  AC63 HCT 116 C121(0.78)  LDD0644  [9]
 LDCM0328  AC64 HCT 116 C121(0.66)  LDD0645  [9]
 LDCM0329  AC65 HCT 116 C121(0.35)  LDD0646  [9]
 LDCM0330  AC66 HCT 116 C121(0.31)  LDD0647  [9]
 LDCM0331  AC67 HCT 116 C121(0.18)  LDD0648  [9]
 LDCM0332  AC68 HCT 116 C121(0.79)  LDD0649  [9]
 LDCM0333  AC69 HCT 116 C121(0.63)  LDD0650  [9]
 LDCM0334  AC7 PaTu 8988t C121(1.37)  LDD1213  [9]
 LDCM0335  AC70 HCT 116 C121(0.43)  LDD0652  [9]
 LDCM0336  AC71 HCT 116 C121(0.76)  LDD0653  [9]
 LDCM0337  AC72 HCT 116 C121(1.02)  LDD0654  [9]
 LDCM0338  AC73 HCT 116 C121(0.55)  LDD0655  [9]
 LDCM0339  AC74 HCT 116 C121(0.50)  LDD0656  [9]
 LDCM0340  AC75 HCT 116 C121(0.46)  LDD0657  [9]
 LDCM0341  AC76 HCT 116 C121(0.95)  LDD0658  [9]
 LDCM0342  AC77 HCT 116 C121(0.63)  LDD0659  [9]
 LDCM0343  AC78 HCT 116 C121(0.62)  LDD0660  [9]
 LDCM0344  AC79 HCT 116 C121(1.16)  LDD0661  [9]
 LDCM0345  AC8 PaTu 8988t C121(0.69)  LDD1224  [9]
 LDCM0346  AC80 HCT 116 C121(0.90)  LDD0663  [9]
 LDCM0347  AC81 HCT 116 C121(0.80)  LDD0664  [9]
 LDCM0348  AC82 HCT 116 C121(0.28)  LDD0665  [9]
 LDCM0349  AC83 HCT 116 C121(0.75)  LDD0666  [9]
 LDCM0350  AC84 HCT 116 C121(0.76)  LDD0667  [9]
 LDCM0351  AC85 HCT 116 C121(0.68)  LDD0668  [9]
 LDCM0352  AC86 HCT 116 C121(0.67)  LDD0669  [9]
 LDCM0353  AC87 HCT 116 C121(0.65)  LDD0670  [9]
 LDCM0354  AC88 HCT 116 C121(0.73)  LDD0671  [9]
 LDCM0355  AC89 HCT 116 C121(0.63)  LDD0672  [9]
 LDCM0357  AC90 HCT 116 C121(0.75)  LDD0674  [9]
 LDCM0358  AC91 HCT 116 C121(0.75)  LDD0675  [9]
 LDCM0359  AC92 HCT 116 C121(0.73)  LDD0676  [9]
 LDCM0360  AC93 HCT 116 C121(0.70)  LDD0677  [9]
 LDCM0361  AC94 HCT 116 C121(1.10)  LDD0678  [9]
 LDCM0362  AC95 HCT 116 C121(0.56)  LDD0679  [9]
 LDCM0363  AC96 HCT 116 C121(0.87)  LDD0680  [9]
 LDCM0364  AC97 HCT 116 C121(0.62)  LDD0681  [9]
 LDCM0365  AC98 HCT 116 C121(0.59)  LDD0682  [9]
 LDCM0366  AC99 HCT 116 C121(0.66)  LDD0683  [9]
 LDCM0545  Acetamide MDA-MB-231 C173(0.63)  LDD2138  [5]
 LDCM0520  AKOS000195272 MDA-MB-231 C173(0.67); C121(0.63)  LDD2113  [5]
 LDCM0248  AKOS034007472 PaTu 8988t C121(0.50)  LDD1127  [9]
 LDCM0356  AKOS034007680 PaTu 8988t C121(0.63)  LDD1235  [9]
 LDCM0275  AKOS034007705 PaTu 8988t C121(0.47)  LDD1154  [9]
 LDCM0156  Aniline NCI-H1299 12.14  LDD0403  [1]
 LDCM0498  BS-3668 MDA-MB-231 C173(1.14)  LDD2091  [5]
 LDCM0108  Chloroacetamide HeLa C173(0.00); H14(0.00)  LDD0222  [18]
 LDCM0632  CL-Sc Hep-G2 C173(1.95); C121(0.90); C173(0.23)  LDD2227  [21]
 LDCM0367  CL1 HCT 116 C121(0.83)  LDD0684  [9]
 LDCM0368  CL10 HCT 116 C121(0.95)  LDD0685  [9]
 LDCM0369  CL100 PaTu 8988t C121(0.82)  LDD1248  [9]
 LDCM0370  CL101 PaTu 8988t C121(0.82)  LDD1249  [9]
 LDCM0371  CL102 PaTu 8988t C121(0.95)  LDD1250  [9]
 LDCM0372  CL103 PaTu 8988t C121(0.62)  LDD1251  [9]
 LDCM0373  CL104 PaTu 8988t C121(0.81)  LDD1252  [9]
 LDCM0374  CL105 PaTu 8988t C121(1.13)  LDD1253  [9]
 LDCM0375  CL106 PaTu 8988t C121(0.99)  LDD1254  [9]
 LDCM0376  CL107 PaTu 8988t C121(1.00)  LDD1255  [9]
 LDCM0377  CL108 PaTu 8988t C121(1.08)  LDD1256  [9]
 LDCM0378  CL109 PaTu 8988t C121(1.08)  LDD1257  [9]
 LDCM0379  CL11 HCT 116 C121(1.05)  LDD0696  [9]
 LDCM0380  CL110 PaTu 8988t C121(0.71)  LDD1259  [9]
 LDCM0381  CL111 PaTu 8988t C121(0.65)  LDD1260  [9]
 LDCM0382  CL112 HEK-293T C173(1.21); C121(1.01); C53(1.14)  LDD1586  [26]
 LDCM0383  CL113 HEK-293T C173(1.46); C121(1.03); C53(1.08)  LDD1587  [26]
 LDCM0384  CL114 HEK-293T C173(1.07); C121(1.23); C53(1.08)  LDD1588  [26]
 LDCM0385  CL115 HEK-293T C173(1.34); C121(1.15); C53(1.26)  LDD1589  [26]
 LDCM0386  CL116 HEK-293T C173(1.29); C121(1.03); C53(1.10)  LDD1590  [26]
 LDCM0387  CL117 PaTu 8988t C121(0.92)  LDD1266  [9]
 LDCM0388  CL118 PaTu 8988t C121(1.01)  LDD1267  [9]
 LDCM0389  CL119 PaTu 8988t C121(0.98)  LDD1268  [9]
 LDCM0390  CL12 HCT 116 C121(1.09)  LDD0707  [9]
 LDCM0391  CL120 PaTu 8988t C121(0.61)  LDD1270  [9]
 LDCM0392  CL121 PaTu 8988t C121(0.74)  LDD1271  [9]
 LDCM0393  CL122 PaTu 8988t C121(0.68)  LDD1272  [9]
 LDCM0394  CL123 PaTu 8988t C121(0.51)  LDD1273  [9]
 LDCM0395  CL124 PaTu 8988t C121(0.37)  LDD1274  [9]
 LDCM0396  CL125 HCT 116 C121(1.26)  LDD0713  [9]
 LDCM0397  CL126 HCT 116 C121(0.73)  LDD0714  [9]
 LDCM0398  CL127 HCT 116 C121(0.95)  LDD0715  [9]
 LDCM0399  CL128 HCT 116 C121(1.28)  LDD0716  [9]
 LDCM0400  CL13 HCT 116 C121(1.40)  LDD0717  [9]
 LDCM0401  CL14 HCT 116 C121(0.85)  LDD0718  [9]
 LDCM0402  CL15 HCT 116 C121(1.12)  LDD0719  [9]
 LDCM0403  CL16 PaTu 8988t C121(0.85)  LDD1282  [9]
 LDCM0404  CL17 PaTu 8988t C121(0.93)  LDD1283  [9]
 LDCM0405  CL18 PaTu 8988t C121(0.74)  LDD1284  [9]
 LDCM0406  CL19 PaTu 8988t C121(0.83)  LDD1285  [9]
 LDCM0407  CL2 HCT 116 C121(0.81)  LDD0724  [9]
 LDCM0408  CL20 PaTu 8988t C121(0.79)  LDD1287  [9]
 LDCM0409  CL21 PaTu 8988t C121(0.58)  LDD1288  [9]
 LDCM0410  CL22 PaTu 8988t C121(0.72)  LDD1289  [9]
 LDCM0411  CL23 PaTu 8988t C121(0.50)  LDD1290  [9]
 LDCM0412  CL24 PaTu 8988t C121(0.56)  LDD1291  [9]
 LDCM0413  CL25 PaTu 8988t C121(0.47)  LDD1292  [9]
 LDCM0414  CL26 PaTu 8988t C121(0.57)  LDD1293  [9]
 LDCM0415  CL27 PaTu 8988t C121(0.59)  LDD1294  [9]
 LDCM0416  CL28 PaTu 8988t C121(0.55)  LDD1295  [9]
 LDCM0417  CL29 PaTu 8988t C121(0.40)  LDD1296  [9]
 LDCM0418  CL3 HCT 116 C121(0.83)  LDD0735  [9]
 LDCM0419  CL30 PaTu 8988t C121(0.48)  LDD1298  [9]
 LDCM0420  CL31 PaTu 8988t C121(0.81)  LDD1299  [9]
 LDCM0421  CL32 PaTu 8988t C121(0.87)  LDD1300  [9]
 LDCM0422  CL33 PaTu 8988t C121(0.51)  LDD1301  [9]
 LDCM0423  CL34 PaTu 8988t C121(0.55)  LDD1302  [9]
 LDCM0424  CL35 PaTu 8988t C121(0.52)  LDD1303  [9]
 LDCM0425  CL36 PaTu 8988t C121(0.36)  LDD1304  [9]
 LDCM0426  CL37 PaTu 8988t C121(0.47)  LDD1305  [9]
 LDCM0428  CL39 PaTu 8988t C121(0.54)  LDD1307  [9]
 LDCM0429  CL4 HCT 116 C121(0.89)  LDD0746  [9]
 LDCM0430  CL40 PaTu 8988t C121(0.87)  LDD1309  [9]
 LDCM0431  CL41 PaTu 8988t C121(0.65)  LDD1310  [9]
 LDCM0432  CL42 PaTu 8988t C121(0.72)  LDD1311  [9]
 LDCM0433  CL43 PaTu 8988t C121(0.62)  LDD1312  [9]
 LDCM0434  CL44 PaTu 8988t C121(0.71)  LDD1313  [9]
 LDCM0435  CL45 PaTu 8988t C121(0.62)  LDD1314  [9]
 LDCM0436  CL46 PaTu 8988t C121(0.93)  LDD1315  [9]
 LDCM0437  CL47 PaTu 8988t C121(0.78)  LDD1316  [9]
 LDCM0438  CL48 PaTu 8988t C121(0.88)  LDD1317  [9]
 LDCM0439  CL49 PaTu 8988t C121(1.03)  LDD1318  [9]
 LDCM0440  CL5 HCT 116 C121(0.98)  LDD0757  [9]
 LDCM0441  CL50 PaTu 8988t C121(0.93)  LDD1320  [9]
 LDCM0442  CL51 PaTu 8988t C121(0.85)  LDD1321  [9]
 LDCM0443  CL52 PaTu 8988t C121(0.97)  LDD1322  [9]
 LDCM0444  CL53 PaTu 8988t C121(0.63)  LDD1323  [9]
 LDCM0445  CL54 PaTu 8988t C121(0.52)  LDD1324  [9]
 LDCM0446  CL55 PaTu 8988t C121(0.71)  LDD1325  [9]
 LDCM0447  CL56 PaTu 8988t C121(0.16)  LDD1326  [9]
 LDCM0448  CL57 PaTu 8988t C121(0.61)  LDD1327  [9]
 LDCM0449  CL58 PaTu 8988t C121(0.65)  LDD1328  [9]
 LDCM0450  CL59 PaTu 8988t C121(0.44)  LDD1329  [9]
 LDCM0451  CL6 HCT 116 C121(0.79)  LDD0768  [9]
 LDCM0452  CL60 PaTu 8988t C121(0.68)  LDD1331  [9]
 LDCM0453  CL61 PaTu 8988t C121(0.86)  LDD1332  [9]
 LDCM0454  CL62 PaTu 8988t C121(1.06)  LDD1333  [9]
 LDCM0455  CL63 PaTu 8988t C121(1.03)  LDD1334  [9]
 LDCM0456  CL64 PaTu 8988t C121(1.29)  LDD1335  [9]
 LDCM0457  CL65 PaTu 8988t C121(1.14)  LDD1336  [9]
 LDCM0458  CL66 PaTu 8988t C121(1.12)  LDD1337  [9]
 LDCM0459  CL67 PaTu 8988t C121(1.19)  LDD1338  [9]
 LDCM0460  CL68 PaTu 8988t C121(1.07)  LDD1339  [9]
 LDCM0461  CL69 PaTu 8988t C121(1.03)  LDD1340  [9]
 LDCM0462  CL7 HCT 116 C121(1.12)  LDD0779  [9]
 LDCM0463  CL70 PaTu 8988t C121(0.92)  LDD1342  [9]
 LDCM0464  CL71 PaTu 8988t C121(1.11)  LDD1343  [9]
 LDCM0465  CL72 PaTu 8988t C121(1.13)  LDD1344  [9]
 LDCM0466  CL73 PaTu 8988t C121(1.05)  LDD1345  [9]
 LDCM0467  CL74 PaTu 8988t C121(1.00)  LDD1346  [9]
 LDCM0469  CL76 PaTu 8988t C121(0.62)  LDD1348  [9]
 LDCM0470  CL77 PaTu 8988t C121(0.79)  LDD1349  [9]
 LDCM0471  CL78 PaTu 8988t C121(0.72)  LDD1350  [9]
 LDCM0472  CL79 PaTu 8988t C121(1.08)  LDD1351  [9]
 LDCM0473  CL8 HCT 116 C121(0.69)  LDD0790  [9]
 LDCM0474  CL80 PaTu 8988t C121(0.76)  LDD1353  [9]
 LDCM0475  CL81 PaTu 8988t C121(0.66)  LDD1354  [9]
 LDCM0476  CL82 PaTu 8988t C121(0.66)  LDD1355  [9]
 LDCM0477  CL83 PaTu 8988t C121(0.63)  LDD1356  [9]
 LDCM0478  CL84 PaTu 8988t C121(0.72)  LDD1357  [9]
 LDCM0479  CL85 PaTu 8988t C121(1.04)  LDD1358  [9]
 LDCM0480  CL86 PaTu 8988t C121(0.81)  LDD1359  [9]
 LDCM0481  CL87 PaTu 8988t C121(0.57)  LDD1360  [9]
 LDCM0482  CL88 PaTu 8988t C121(0.65)  LDD1361  [9]
 LDCM0483  CL89 PaTu 8988t C121(0.78)  LDD1362  [9]
 LDCM0484  CL9 HCT 116 C121(0.97)  LDD0801  [9]
 LDCM0485  CL90 PaTu 8988t C121(0.99)  LDD1364  [9]
 LDCM0486  CL91 PaTu 8988t C121(0.70)  LDD1365  [9]
 LDCM0487  CL92 PaTu 8988t C121(0.71)  LDD1366  [9]
 LDCM0488  CL93 PaTu 8988t C121(0.65)  LDD1367  [9]
 LDCM0489  CL94 PaTu 8988t C121(0.54)  LDD1368  [9]
 LDCM0490  CL95 PaTu 8988t C121(0.45)  LDD1369  [9]
 LDCM0491  CL96 PaTu 8988t C121(0.66)  LDD1370  [9]
 LDCM0492  CL97 PaTu 8988t C121(0.74)  LDD1371  [9]
 LDCM0493  CL98 PaTu 8988t C121(0.64)  LDD1372  [9]
 LDCM0494  CL99 PaTu 8988t C121(0.78)  LDD1373  [9]
 LDCM0495  E2913 HEK-293T C173(1.34); C121(1.07); C53(1.12)  LDD1698  [26]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C121(0.99); C173(0.83)  LDD1702  [5]
 LDCM0625  F8 Ramos C173(1.31); C121(0.53)  LDD2187  [27]
 LDCM0572  Fragment10 Ramos C173(1.12); C121(0.79)  LDD2189  [27]
 LDCM0573  Fragment11 Ramos C173(0.25); C121(1.75)  LDD2190  [27]
 LDCM0574  Fragment12 Ramos C173(0.78); C121(0.74)  LDD2191  [27]
 LDCM0575  Fragment13 Ramos C173(0.94); C121(0.60)  LDD2192  [27]
 LDCM0576  Fragment14 Ramos C173(0.55); C121(0.60)  LDD2193  [27]
 LDCM0579  Fragment20 Ramos C173(0.97); C121(0.83)  LDD2194  [27]
 LDCM0580  Fragment21 Ramos C173(0.81); C121(0.83)  LDD2195  [27]
 LDCM0582  Fragment23 Ramos C173(0.91); C121(0.72)  LDD2196  [27]
 LDCM0578  Fragment27 Ramos C173(0.89); C121(0.85)  LDD2197  [27]
 LDCM0586  Fragment28 Ramos C173(0.73); C121(0.48)  LDD2198  [27]
 LDCM0588  Fragment30 Ramos C173(1.27); C121(1.55)  LDD2199  [27]
 LDCM0589  Fragment31 Ramos C173(0.73); C121(0.78)  LDD2200  [27]
 LDCM0590  Fragment32 Ramos C173(1.39); C121(0.52)  LDD2201  [27]
 LDCM0468  Fragment33 PaTu 8988t C121(1.14)  LDD1347  [9]
 LDCM0596  Fragment38 Ramos C173(0.81); C121(1.01)  LDD2203  [27]
 LDCM0566  Fragment4 Ramos C173(0.82); C121(0.84)  LDD2184  [27]
 LDCM0427  Fragment51 PaTu 8988t C121(0.46)  LDD1306  [9]
 LDCM0610  Fragment52 Ramos C173(1.09)  LDD2204  [27]
 LDCM0614  Fragment56 Ramos C173(1.47); C121(1.56)  LDD2205  [27]
 LDCM0569  Fragment7 Ramos C173(0.88); C121(0.71)  LDD2186  [27]
 LDCM0571  Fragment9 Ramos C173(0.89); C121(0.65)  LDD2188  [27]
 LDCM0107  IAA HeLa N.A.  LDD0221  [18]
 LDCM0022  KB02 HEK-293T C173(1.17); C121(0.99)  LDD1492  [26]
 LDCM0023  KB03 HEK-293T C173(1.01); C121(0.92)  LDD1497  [26]
 LDCM0024  KB05 HMCB C121(2.16)  LDD3312  [28]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C173(0.78)  LDD2102  [5]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C173(0.44)  LDD2121  [5]
 LDCM0109  NEM HeLa H14(0.00); K3(0.00)  LDD0223  [18]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C173(1.38)  LDD2090  [5]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C173(0.87)  LDD2093  [5]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C173(1.15); C121(1.33)  LDD2094  [5]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C121(0.91)  LDD2096  [5]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C173(0.79)  LDD2097  [5]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C173(0.56); C121(0.91)  LDD2098  [5]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C173(1.46)  LDD2099  [5]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C173(0.96); C121(0.46)  LDD2100  [5]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C173(0.74)  LDD2101  [5]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C173(0.66); C121(0.38)  LDD2104  [5]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C173(0.78)  LDD2106  [5]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C173(1.10)  LDD2107  [5]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C173(0.71); C121(0.58)  LDD2108  [5]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C173(1.10); C121(0.85)  LDD2109  [5]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C173(2.08)  LDD2110  [5]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C173(1.49)  LDD2111  [5]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C173(0.59)  LDD2114  [5]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C173(0.47)  LDD2115  [5]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C121(1.49)  LDD2119  [5]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C121(1.31)  LDD2120  [5]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C173(1.10)  LDD2123  [5]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C173(1.13); C121(1.10)  LDD2125  [5]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C173(1.41); C121(0.76)  LDD2127  [5]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C173(1.06)  LDD2129  [5]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C173(0.30)  LDD2133  [5]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C173(0.34); C121(0.73)  LDD2134  [5]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C173(1.04); C121(1.07)  LDD2135  [5]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C173(1.68)  LDD2136  [5]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C173(1.48); C121(1.26)  LDD2137  [5]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C173(0.92)  LDD2140  [5]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C173(0.75)  LDD2141  [5]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C173(3.06); C121(2.41)  LDD2144  [5]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C173(4.97)  LDD2145  [5]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C173(1.37)  LDD2146  [5]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C121(1.77)  LDD2147  [5]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C173(0.38); C121(0.48)  LDD2148  [5]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C173(0.45)  LDD2150  [5]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C173(0.99)  LDD2153  [5]
 LDCM0628  OTUB2-COV-1 HEK-293T C173(0.85)  LDD2207  [29]
 LDCM0029  Quercetin HEK-293T 4.85  LDD0181  [6]
 LDCM0131  RA190 MM1.R 3.33  LDD0300  [8]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 10 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Palmitoyltransferase ZDHHC15 (ZDHHC15) DHHC palmitoyltransferase family Q96MV8
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) EBP family Q15125
Very long chain fatty acid elongase 4 (ELOVL4) ELO family Q9GZR5
Prostaglandin E synthase (PTGES) MAPEG family O14684
Ubiquitin carboxyl-terminal hydrolase 20 (USP20) Peptidase C19 family Q9Y2K6
Ribonuclease kappa (RNASEK) RNase K family Q6P5S7
17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13) Short-chain dehydrogenases/reductases (SDR) family Q7Z5P4
ADP-ribosylation factor-like protein 16 (ARL16) Arf family Q0P5N6
Plasma membrane ascorbate-dependent reductase CYBRD1 (CYBRD1) . Q53TN4
Transmembrane ascorbate-dependent reductase CYB561 (CYB561) . P49447
Transporter and channel
Click To Hide/Show 7 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Aquaporin-6 (AQP6) MIP/aquaporin (TC 1.A.8) family Q13520
Sodium channel regulatory subunit beta-3 (SCN3B) Sodium channel auxiliary subunit SCN3B family Q9NY72
Vesicle-associated membrane protein-associated protein A (VAPA) VAMP-associated protein (VAP) (TC 9.B.17) family Q9P0L0
Protrudin (ZFYVE27) . Q5T4F4
Syntenin-1 (SDCBP) . O00560
Thioredoxin-related transmembrane protein 2 (TMX2) . Q9Y320
Transmembrane protein 101 (TMEM101) . Q96IK0
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger and BTB domain-containing protein 22 (ZBTB22) Krueppel C2H2-type zinc-finger protein family O15209
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable G-protein coupled receptor 25 (GPR25) G-protein coupled receptor 1 family O00155
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
B-cell antigen receptor complex-associated protein alpha chain (CD79A) . P11912
Other
Click To Hide/Show 13 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Receptor expression-enhancing protein 4 (REEP4) DP1 family Q9H6H4
Membrane protein FAM174A (FAM174A) FAM174 family Q8TBP5
Protein jagunal homolog 1 (JAGN1) Jagunal family Q8N5M9
Keratin-associated protein 9-2 (KRTAP9-2) KRTAP type 9 family Q9BYQ4
Oxysterol-binding protein-related protein 1 (OSBPL1A) OSBP family Q9BXW6
Reticulophagy regulator 3 (RETREG3) RETREG family Q86VR2
Regulator of microtubule dynamics protein 2 (RMDN2) RMDN family Q96LZ7
Tetratricopeptide repeat protein 39B (TTC39B) TTC39 family Q5VTQ0
Protein YIF1A (YIF1A) YIF1 family O95070
Emerin (EMD) . P50402
Receptor-binding cancer antigen expressed on SiSo cells (EBAG9) . O00559
Superkiller complex protein 8 (SKIC8) . Q9GZS3
Transmembrane protein 252 (TMEM252) . Q8N6L7

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
3 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
4 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
5 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
6 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
7 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
8 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.
9 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
10 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
11 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
12 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
13 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
14 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
15 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
16 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
17 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
18 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
19 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
20 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
21 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD007570
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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Mass spectrometry data entry: PXD047840
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