General Information of Experiment

Probe Name TPP-AC  Probe Info 
Probe concentration 10 uM
Criteria Other data
In Vivo Experiment Model Model Type Living cell
Derived Tissue Cervix uteri
Disease Model Endocervical adenocarcinoma [ICD-11:2C77]
Model Name Human endocervical adenocarcinoma cells (HeLa)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 131 Protein Related to This Bioclass
Target ID Target Name
 LDTP10954  3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10)
 LDTP02329  3-ketoacyl-CoA thiolase, peroxisomal (ACAA1)
 LDTP18414  5'-nucleotidase domain-containing protein 2 (NT5DC2)
 LDTP02522  60 kDa heat shock protein, mitochondrial (HSPD1)
 LDTP01273  Acyl-protein thioesterase 1 (LYPLA1)
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK)
 LDTP04636  Adenylate kinase 2, mitochondrial (AK2)
 LDTP11059  ADP-ribose glycohydrolase MACROD1 (MACROD1)
 LDTP05192  ADP-ribosylation factor 1 (ARF1)
 LDTP02942  ADP-ribosylation factor 4 (ARF4)
 LDTP13462  ADP-sugar pyrophosphatase (NUDT5)
 LDTP02074  Aldehyde dehydrogenase, mitochondrial (ALDH2)
 LDTP02072  Arginase-1 (ARG1)
 LDTP02888  Aspartate aminotransferase, cytoplasmic (GOT1)
 LDTP02150  ATP synthase subunit beta, mitochondrial (ATP5F1B)
 LDTP08440  ATP-binding cassette sub-family A member 9 (ABCA9)
 LDTP01382  ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (CLPX)
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A)
 LDTP02216  Beta-hexosaminidase subunit beta (HEXB)
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5)
 LDTP05992  Bleomycin hydrolase (BLMH)
 LDTP12163  Calcyclin-binding protein (CACYBP)
 LDTP03591  Carbamoyl-phosphate synthase [ammonia], mitochondrial (CPS1)
 LDTP13329  Carboxypeptidase A4 (CPA4)
 LDTP03616  Caspase-14 (CASP14)
 LDTP02001  Catalase (CAT)
 LDTP02223  Cathepsin B (CTSB)
 LDTP02198  Cathepsin D (CTSD)
 LDTP04886  Cell division control protein 42 homolog (CDC42)
 LDTP15505  Choline dehydrogenase, mitochondrial (CHDH)
 LDTP01205  Citrate synthase, mitochondrial (CS)
 LDTP03610  Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1)
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2)
 LDTP04144  Cytochrome b-c1 complex subunit Rieske, mitochondrial (UQCRFS1)
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2)
 LDTP02283  Cytochrome c1, heme protein, mitochondrial (CYC1)
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH)
 LDTP02362  Dihydrolipoyl dehydrogenase, mitochondrial (DLD)
 LDTP03829  Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST)
 LDTP04572  Dipeptidyl peptidase 1 (CTSC)
 LDTP05136  DNA-dependent protein kinase catalytic subunit (PRKDC)
 LDTP01047  Dolichol-phosphate mannosyltransferase subunit 1 (DPM1)
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A)
 LDTP02694  Electron transfer flavoprotein subunit alpha, mitochondrial (ETFA)
 LDTP03849  Electron transfer flavoprotein subunit beta (ETFB)
 LDTP04251  Elongation factor Tu, mitochondrial (TUFM)
 LDTP02534  Endoplasmic reticulum chaperone BiP (HSPA5)
 LDTP03965  Enoyl-CoA delta isomerase 1, mitochondrial (ECI1)
 LDTP03518  Enoyl-CoA hydratase, mitochondrial (ECHS1)
 LDTP06089  Eukaryotic initiation factor 4A-II (EIF4A2)
 LDTP02008  Fructose-bisphosphate aldolase A (ALDOA)
 LDTP01164  Gamma-glutamylcyclotransferase (GGCT)
 LDTP02651  Gamma-interferon-inducible lysosomal thiol reductase (IFI30)
 LDTP02333  Glutathione S-transferase P (GSTP1)
 LDTP05007  GTP-binding nuclear protein Ran (RAN)
 LDTP15740  GTP-binding protein Di-Ras2 (DIRAS2)
 LDTP02541  Heat shock cognate 71 kDa protein (HSPA8)
 LDTP02602  Histidine--tRNA ligase, cytoplasmic (HARS1)
 LDTP02743  Insulin-degrading enzyme (IDE)
 LDTP01333  Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1)
 LDTP06214  Kinesin-like protein KIF22 (KIF22)
 LDTP12835  Large ribosomal subunit protein mL39 (MRPL39)
 LDTP12098  Large ribosomal subunit protein mL44 (MRPL44)
 LDTP06080  Large ribosomal subunit protein mL62 (MRPL58)
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1)
 LDTP02505  Lysosomal protective protein (CTSA)
 LDTP03908  Malate dehydrogenase, mitochondrial (MDH2)
 LDTP12227  Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2)
 LDTP10776  Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCC1)
 LDTP01220  Mitochondrial-processing peptidase subunit beta (PMPCB)
 LDTP13496  Myosin-13 (MYH13)
 LDTP13495  Myosin-2 (MYH2)
 LDTP05943  Myotubularin-related protein 1 (MTMR1)
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT)
 LDTP02798  NAD(P)H dehydrogenase [quinone] 1 (NQO1)
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9)
 LDTP02995  NADH dehydrogenase flavoprotein 2, mitochondrial (NDUFV2)
 LDTP01238  NADH dehydrogenase iron-sulfur protein 3, mitochondrial (NDUFS3)
 LDTP01165  NADH dehydrogenase iron-sulfur protein 7, mitochondrial (NDUFS7)
 LDTP01986  NADH-ubiquinone oxidoreductase chain 5 (MT-ND5)
 LDTP04164  NADP-dependent malic enzyme (ME1)
 LDTP02796  Nucleoside diphosphate kinase A (NME1)
 LDTP03945  Patatin-like phospholipase domain-containing protein 4 (PNPLA4)
 LDTP05028  Peptidyl-prolyl cis-trans isomerase A (PPIA)
 LDTP03216  Peptidyl-prolyl cis-trans isomerase B (PPIB)
 LDTP13989  Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2)
 LDTP05503  Peroxiredoxin-1 (PRDX1)
 LDTP05773  Peroxiredoxin-4 (PRDX4)
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1)
 LDTP12040  Prostaglandin E synthase 2 (PTGES2)
 LDTP03330  Proteasome subunit alpha type-1 (PSMA1)
 LDTP03332  Proteasome subunit alpha type-3 (PSMA3)
 LDTP03333  Proteasome subunit alpha type-4 (PSMA4)
 LDTP03413  Proteasome subunit alpha type-5 (PSMA5)
 LDTP00449  Proteasome subunit alpha type-7 (PSMA7)
 LDTP03419  Proteasome subunit beta type-5 (PSMB5)
 LDTP03418  Proteasome subunit beta type-6 (PSMB6)
 LDTP10862  Proteasome subunit beta type-7 (PSMB7)
 LDTP06314  Protein disulfide-isomerase A6 (PDIA6)
 LDTP05339  Protein kinase C epsilon type (PRKCE)
 LDTP00877  Protein SCO2 homolog, mitochondrial (SCO2)
 LDTP00798  Protein-glutamine gamma-glutamyltransferase 5 (TGM5)
 LDTP17178  Putative malate dehydrogenase 1B (MDH1B)
 LDTP03644  Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1)
 LDTP02576  Pyruvate carboxylase, mitochondrial (PC)
 LDTP02733  Pyruvate kinase PKM (PKM)
 LDTP02768  Ras-related C3 botulinum toxin substrate 2 (RAC2)
 LDTP04895  Ras-related protein Rab-10 (RAB10)
 LDTP04399  Ras-related protein Rab-7a (RAB7A)
 LDTP04910  Ras-related protein Rap-1b (RAP1B)
 LDTP04134  Retinaldehyde dehydrogenase 3 (ALDH1A3)
 LDTP06920  Retroviral-like aspartic protease 1 (ASPRV1)
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2)
 LDTP14931  Scavenger receptor cysteine-rich domain-containing protein SCART1 (SCART1)
 LDTP03689  Serine hydroxymethyltransferase, mitochondrial (SHMT2)
 LDTP12319  Serine--tRNA ligase, mitochondrial (SARS2)
 LDTP11590  Serine/threonine-protein kinase DCLK3 (DCLK3)
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2)
 LDTP03223  Small ribosomal subunit protein uS3 (RPS3)
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1)
 LDTP03572  Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA)
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB)
 LDTP04566  Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1)
 LDTP02502  Thioredoxin (TXN)
 LDTP01707  Thioredoxin domain-containing protein 12 (TXNDC12)
 LDTP03515  Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3)
 LDTP03023  Thymidine phosphorylase (TYMP)
 LDTP03258  Thymidylate kinase (DTYMK)
 LDTP04851  Triosephosphate isomerase (TPI1)
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1)
 LDTP05074  Tubulin alpha-1B chain (TUBA1B)
Transporter and channel
Click to Show/Hide to Show 33 Protein Related to This Bioclass
Target ID Target Name
 LDTP04953  14-3-3 protein gamma (YWHAG)
 LDTP02087  ADP/ATP translocase 2 (SLC25A5)
 LDTP02609  ADP/ATP translocase 3 (SLC25A6)
 LDTP02010  Annexin A1 (ANXA1)
 LDTP02199  Annexin A2 (ANXA2)
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB)
 LDTP01804  ATP synthase subunit a (MT-ATP6)
 LDTP03327  ATP synthase subunit alpha, mitochondrial (ATP5F1A)
 LDTP14509  ATP synthase subunit d, mitochondrial (ATP5PD)
 LDTP04150  ATP synthase subunit O, mitochondrial (ATP5PO)
 LDTP13599  Calcium load-activated calcium channel (TMCO1)
 LDTP03405  Calnexin (CANX)
 LDTP03402  Calreticulin (CALR)
 LDTP05510  Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP)
 LDTP01133  Copine-3 (CPNE3)
 LDTP05056  Eukaryotic translation initiation factor 5A-1 (EIF5A)
 LDTP11161  Extended synaptotagmin-1 (ESYT1)
 LDTP03107  Filamin-A (FLNA)
 LDTP02929  Galectin-3 (LGALS3)
 LDTP10728  Gasdermin-A (GSDMA)
 LDTP02262  Heat shock protein HSP 90-beta (HSP90AB1)
 LDTP05305  Large neutral amino acids transporter small subunit 1 (SLC7A5)
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2)
 LDTP01352  PRA1 family protein 3 (ARL6IP5)
 LDTP03717  Prohibitin 1 (PHB1)
 LDTP05238  Solute carrier family 25 member 3 (SLC25A3)
 LDTP05273  Spectrin beta chain, non-erythrocytic 1 (SPTBN1)
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10)
 LDTP03811  V-type proton ATPase subunit E 1 (ATP6V1E1)
 LDTP01556  Vesicle-associated membrane protein-associated protein B/C (VAPB)
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2)
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3)
 LDTP08816  Voltage-dependent calcium channel beta subunit-associated regulatory protein (CBARP)
Transcription factor
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name
 LDTP01337  Attractin (ATRN)
 LDTP12507  Chromatin accessibility complex protein 1 (CHRAC1)
 LDTP12355  DNA methyltransferase 1-associated protein 1 (DMAP1)
 LDTP02343  High mobility group protein B1 (HMGB1)
 LDTP03363  High mobility group protein B2 (HMGB2)
 LDTP05235  Transcription factor A, mitochondrial (TFAM)
GPCR
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name
 LDTP09993  KiSS-1 receptor (KISS1R)
Immunoglobulin
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name
 LDTP02040  HLA class I histocompatibility antigen, A alpha chain (HLA-A)
Cytokine and receptor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name
 LDTP12899  Interleukin-36 gamma (IL36G)
Other
Click to Show/Hide to Show 87 Protein Related to This Bioclass
Target ID Target Name
 LDTP04844  Actin-related protein 2/3 complex subunit 4 (ARPC4)
 LDTP01814  Alpha-2-macroglobulin (A2M)
 LDTP02631  Alpha-actinin-1 (ACTN1)
 LDTP11725  AP-5 complex subunit mu-1 (AP5M1)
 LDTP06845  BTB/POZ domain-containing protein KCTD21 (KCTD21)
 LDTP05778  Chromobox protein homolog 3 (CBX3)
 LDTP01195  Core histone macro-H2A.1 (MACROH2A1)
 LDTP01819  Cystatin-S (CST4)
 LDTP03106  Cysteine and glycine-rich protein 1 (CSRP1)
 LDTP06542  Cysteine and glycine-rich protein 2 (CSRP2)
 LDTP03283  Elongation factor 1-beta (EEF1B2)
 LDTP03509  Endoplasmic reticulum resident protein 29 (ERP29)
 LDTP10046  Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1)
 LDTP13097  Epidermal growth factor receptor substrate 15-like 1 (EPS15L1)
 LDTP04743  Eukaryotic translation initiation factor 6 (EIF6)
 LDTP11674  Extracellular glycoprotein lacritin (LACRT)
 LDTP02145  Gelsolin (GSN)
 LDTP12144  GrpE protein homolog 1, mitochondrial (GRPEL1)
 LDTP03694  Heat shock 70 kDa protein 1-like (HSPA1L)
 LDTP02434  Heat shock 70 kDa protein 1A (HSPA1A)
 LDTP02435  Heat shock 70 kDa protein 1B (HSPA1B)
 LDTP05259  Heterogeneous nuclear ribonucleoprotein U (HNRNPU)
 LDTP02845  Histone H1.2 (H1-2)
 LDTP10506  Histone H2A type 1-H (H2AC12)
 LDTP15019  Histone H3-7 (H3-7)
 LDTP16079  Large ribosomal subunit protein bL17m (MRPL17)
 LDTP14696  Large ribosomal subunit protein bL19m (MRPL19)
 LDTP15237  Large ribosomal subunit protein bL21m (MRPL21)
 LDTP04919  Large ribosomal subunit protein eL15 (RPL15)
 LDTP05509  Large ribosomal subunit protein eL18 (RPL18)
 LDTP05186  Large ribosomal subunit protein eL24 (RPL24)
 LDTP05023  Large ribosomal subunit protein eL31 (RPL31)
 LDTP15922  Large ribosomal subunit protein mL37 (MRPL37)
 LDTP08994  Large ribosomal subunit protein mL43 (MRPL43)
 LDTP09297  Large ribosomal subunit protein mL64 (GADD45GIP1)
 LDTP16113  Large ribosomal subunit protein mL66 (MRPS18A)
 LDTP05024  Large ribosomal subunit protein uL1 (RPL10A)
 LDTP03517  Large ribosomal subunit protein uL11 (RPL12)
 LDTP04105  Large ribosomal subunit protein uL15 (RPL27A)
 LDTP16124  Large ribosomal subunit protein uL16m (MRPL16)
 LDTP05001  Large ribosomal subunit protein uL23 (RPL23A)
 LDTP02944  Large ribosomal subunit protein uL30 (RPL7)
 LDTP14589  Large ribosomal subunit protein uL3m (MRPL3)
 LDTP03236  Loricrin (LORICRIN)
 LDTP07677  Ly6/PLAUR domain-containing protein 5 (LYPD5)
 LDTP04027  Matrin-3 (MATR3)
 LDTP18538  Meteorin (METRN)
 LDTP00487  Myosin regulatory light chain 12B (MYL12B)
 LDTP12953  NADH dehydrogenase 1 alpha subcomplex assembly factor 4 (NDUFAF4)
 LDTP01272  Nucleoplasmin-3 (NPM3)
 LDTP15707  Pancreatic adenocarcinoma up-regulated factor (ZG16B)
 LDTP03931  Peripherin (PRPH)
 LDTP02084  Plasminogen activator inhibitor 2 (SERPINB2)
 LDTP13906  Polymerase delta-interacting protein 2 (POLDIP2)
 LDTP03364  Polypyrimidine tract-binding protein 1 (PTBP1)
 LDTP02413  Polyubiquitin-C (UBC)
 LDTP01932  Prelamin-A/C (LMNA)
 LDTP09219  Protein DBF4 homolog B (DBF4B)
 LDTP03463  Protein S100-A2 (S100A2)
 LDTP03575  Protein S100-A7 (S100A7)
 LDTP02152  Protein S100-A9 (S100A9)
 LDTP06134  Protocadherin Fat 1 (FAT1)
 LDTP04117  Ras GTPase-activating-like protein IQGAP1 (IQGAP1)
 LDTP15847  Rho GDP-dissociation inhibitor 3 (ARHGDIG)
 LDTP02480  RNA-binding protein RO60 (RO60)
 LDTP09682  RUN and FYVE domain-containing protein 2 (RUFY2)
 LDTP03035  Serine protease inhibitor Kazal-type 2 (SPINK2)
 LDTP03825  Serpin B5 (SERPINB5)
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB)
 LDTP02302  Small ribosomal subunit protein eS17 (RPS17)
 LDTP05013  Small ribosomal subunit protein eS25 (RPS25)
 LDTP14653  Small ribosomal subunit protein eS4, Y isoform 1 (RPS4Y1)
 LDTP05176  Small ribosomal subunit protein uS11m (MRPS11)
 LDTP04971  Small ribosomal subunit protein uS12 (RPS23)
 LDTP04110  Small ribosomal subunit protein uS7 (RPS5)
 LDTP04966  Small ribosomal subunit protein uS9 (RPS16)
 LDTP05985  Spectrin alpha chain, non-erythrocytic 1 (SPTAN1)
 LDTP12091  Spermatogenesis-defective protein 39 homolog (VIPAS39)
 LDTP10062  Synapse-associated protein 1 (SYAP1)
 LDTP06557  Synaptophysin-like protein 1 (SYPL1)
 LDTP05113  T-complex protein 1 subunit beta (CCT2)
 LDTP11027  Telomerase protein component 1 (TEP1)
 LDTP11702  Toll-interacting protein (TOLLIP)
 LDTP03846  Transgelin-2 (TAGLN2)
 LDTP02165  Tropomyosin alpha-3 chain (TPM3)
 LDTP01206  Vesicle-trafficking protein SEC22b (SEC22B)
 LDTP02297  Vimentin (VIM)

References

1 Differently Tagged Probes for Protein Profiling of Mitochondria. Chembiochem. 2019 May 2;20(9):1155-1160. doi: 10.1002/cbic.201800735. Epub 2019 Mar 26.