General Information of Target

Target ID LDTP14931
Target Name Scavenger receptor cysteine-rich domain-containing protein SCART1 (SCART1)
Gene Name SCART1
Synonyms
Scavenger receptor cysteine-rich domain-containing protein SCART1; Scavenger receptor family member expressed on T cells 1
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAPARRPAGARLLLVYAGLLAAAAAGLGSPEPGAPSRSRARREPPPGNELPRGPGESRAG
PAARPPEPTAERAHSVDPRDAWMLFVRQSDKGVNGKKRSRGKAKKLKFGLPGPPGPPGPQ
GPPGPIIPPEALLKEFQLLLKGAVRQRERAEPEPCTCGPAGPVAASLAPVSATAGEDDDD
VVGDVLALLAAPLAPGPRAPRVEAAFLCRLRRDALVERRALHELGVYYLPDAEGAFRRGP
GLNLTSGQYRAPVAGFYALAATLHVALGEPPRRGPPRPRDHLRLLICIQSRCQRNASLEA
IMGLESSSELFTISVNGVLYLQMGQWTSVFLDNASGCSLTVRSGSHFSAVLLGV
Target Bioclass
Enzyme
Subcellular location
Membrane
Function May play a role in the immune system, perhaps as a co-receptor on alphabeta and gammadelta T-cells.
Uniprot ID
Q4G0T1
Ensemble ID
ENST00000640237.2
HGNC ID
HGNC:32411

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info 
C226(0.77)  LDD2229  [1]
BTD
 Probe Info 
C472(0.91)  LDD2120  [2]
TPP-AC
 Probe Info 
N.A.  LDD0427  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C472(0.91)  LDD2120  [2]

References

1 A quantitative thiol reactivity profiling platform to analyze redox and electrophile reactive cysteine proteomes. Nat Protoc. 2020 Sep;15(9):2891-2919. doi: 10.1038/s41596-020-0352-2. Epub 2020 Jul 20.
Mass spectrometry data entry: PXD016048
2 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
3 Differently Tagged Probes for Protein Profiling of Mitochondria. Chembiochem. 2019 May 2;20(9):1155-1160. doi: 10.1002/cbic.201800735. Epub 2019 Mar 26.