Details of the Target

General Information of Target

Target ID LDTP01337
Target Name Attractin (ATRN)
Gene Name ATRN
Gene ID 8455
Synonyms
KIAA0548; MGCA; Attractin; DPPT-L; Mahogany homolog
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MVAAAAATEARLRRRTAATAALAGRSGGPHWDWDVTRAGRPGLGAGLRLPRLLSPPLRPR
LLLLLLLLSPPLLLLLLPCEAEAAAAAAAVSGSAAAEAKECDRPCVNGGRCNPGTGQCVC
PAGWVGEQCQHCGGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE
CSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTG
FNITYSFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICN
SSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEYSNLKLPRASHKAVVNGNIMWVVGGYM
FNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNE
LRVFHIHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEY
DLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVD
TQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRW
SVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGFNSLLLSDILVFTSEQCDAHRSEAACLAA
GPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDC
HWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQEC
IALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLASLTTQKKVEFVLKQLR
IMQSSQSMSKLTLTPWVGLRKINVSYWCWEDMSPFTNSLLQWMPSEPSDAGFCGILSEPS
TRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVD
SNAYVASFPFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGS
YKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKC
ENLTTGKHCETCISGFYGDPTNGGKCQPCKCNGHASLCNTNTGKCFCTTKGVKGDECQLC
EVENRYQGNPLRGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINAS
KNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNF
TWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREM
QQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLG
GIPPPGQSGLAVASALVDISQQMPIVYKEKSGAVRNRKQQPPAQPGTCI
Target Bioclass
Transcription factor
Subcellular location
Secreted; Cell membrane
Function
Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system.
Uniprot ID
O75882
Ensemble ID
ENST00000262919.10
HGNC ID
HGNC:885

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A549 SNV: p.T803N DBIA    Probe Info 
EFO27 SNV: p.P884S DBIA    Probe Info 
HCT116 SNV: p.M974I .
HEPG2 SNV: p.H617R .
L428 SNV: p.N107H .
MM1S SNV: p.D1007N .
MOLT4 SNV: p.T978M .
NB1 SNV: p.F1213C .
NCIH446 SNV: p.D810G .
PEO1 SNV: p.A1324S DBIA    Probe Info 
SW1271 SNV: p.N351S .
TOV21G Deletion: p.F231LfsTer8 .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
OPA-S-S-alkyne
 Probe Info  		K1133(1.82)  LDD3494  [1]
DBIA
 Probe Info  		C933(5.43)  LDD3310  [2]
IPM
 Probe Info  		C933(1.55)  LDD1701  [3]
Acrolein
 Probe Info  		N.A.  LDD0231  [4]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [5]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [5]
AOyne
 Probe Info  		13.90  LDD0443  [6]
TER-AC
 Probe Info  		N.A.  LDD0426  [7]
TPP-AC
 Probe Info  		N.A.  LDD0427  [7]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C170
 Probe Info  		15.14  LDD1850  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C158(0.99); C1016(0.99); C1307(0.89); C101(1.07)  LDD1507  [9]
 LDCM0215  AC10 HEK-293T C1428(1.03)  LDD0813  [10]
 LDCM0216  AC100 HEK-293T C1428(1.03); C765(0.89)  LDD0814  [10]
 LDCM0217  AC101 HEK-293T C1428(1.02); C765(0.99)  LDD0815  [10]
 LDCM0218  AC102 HEK-293T C1428(1.04); C765(0.95)  LDD0816  [10]
 LDCM0219  AC103 HEK-293T C1428(0.93); C765(0.98)  LDD0817  [10]
 LDCM0220  AC104 HEK-293T C1428(0.91); C765(1.05)  LDD0818  [10]
 LDCM0221  AC105 HEK-293T C1428(1.13); C765(0.87)  LDD0819  [10]
 LDCM0222  AC106 HEK-293T C1428(1.05); C765(0.94)  LDD0820  [10]
 LDCM0223  AC107 HEK-293T C1428(1.01); C765(0.94)  LDD0821  [10]
 LDCM0224  AC108 HEK-293T C1428(1.09); C765(0.97)  LDD0822  [10]
 LDCM0225  AC109 HEK-293T C1428(0.96); C765(0.95)  LDD0823  [10]
 LDCM0226  AC11 HEK-293T C1428(1.08)  LDD0824  [10]
 LDCM0227  AC110 HEK-293T C1428(1.01); C765(1.07)  LDD0825  [10]
 LDCM0228  AC111 HEK-293T C1428(1.20); C765(0.94)  LDD0826  [10]
 LDCM0229  AC112 HEK-293T C1428(1.07); C765(1.01)  LDD0827  [10]
 LDCM0230  AC113 HEK-293T C1307(0.88); C765(0.74)  LDD0828  [10]
 LDCM0231  AC114 HEK-293T C1307(0.94); C765(0.87)  LDD0829  [10]
 LDCM0232  AC115 HEK-293T C1307(0.97); C765(1.32)  LDD0830  [10]
 LDCM0233  AC116 HEK-293T C1307(0.84); C765(1.09)  LDD0831  [10]
 LDCM0234  AC117 HEK-293T C1307(0.89); C765(1.09)  LDD0832  [10]
 LDCM0235  AC118 HEK-293T C1307(0.73); C765(1.13)  LDD0833  [10]
 LDCM0236  AC119 HEK-293T C1307(0.78); C765(1.00)  LDD0834  [10]
 LDCM0237  AC12 HEK-293T C1428(1.02)  LDD0835  [10]
 LDCM0238  AC120 HEK-293T C1307(0.78); C765(1.51)  LDD0836  [10]
 LDCM0239  AC121 HEK-293T C1307(0.65); C765(0.85)  LDD0837  [10]
 LDCM0240  AC122 HEK-293T C1307(0.74); C765(1.45)  LDD0838  [10]
 LDCM0241  AC123 HEK-293T C1307(0.75); C765(1.12)  LDD0839  [10]
 LDCM0242  AC124 HEK-293T C1307(0.74); C765(1.19)  LDD0840  [10]
 LDCM0243  AC125 HEK-293T C1307(0.70); C765(1.01)  LDD0841  [10]
 LDCM0244  AC126 HEK-293T C1307(0.76); C765(1.02)  LDD0842  [10]
 LDCM0245  AC127 HEK-293T C1307(0.62); C765(1.06)  LDD0843  [10]
 LDCM0259  AC14 HEK-293T C1428(1.06)  LDD0857  [10]
 LDCM0263  AC143 HEK-293T C1307(0.70)  LDD0861  [10]
 LDCM0264  AC144 HEK-293T C1307(0.78)  LDD0862  [10]
 LDCM0265  AC145 HEK-293T C1307(0.86)  LDD0863  [10]
 LDCM0266  AC146 HEK-293T C1307(0.82)  LDD0864  [10]
 LDCM0267  AC147 HEK-293T C1307(0.80)  LDD0865  [10]
 LDCM0268  AC148 HEK-293T C1307(0.82)  LDD0866  [10]
 LDCM0269  AC149 HEK-293T C1307(1.04)  LDD0867  [10]
 LDCM0270  AC15 HEK-293T C1428(1.13)  LDD0868  [10]
 LDCM0271  AC150 HEK-293T C1307(0.79)  LDD0869  [10]
 LDCM0272  AC151 HEK-293T C1307(0.78)  LDD0870  [10]
 LDCM0273  AC152 HEK-293T C1307(0.82)  LDD0871  [10]
 LDCM0274  AC153 HEK-293T C1307(0.86)  LDD0872  [10]
 LDCM0621  AC154 HEK-293T C1307(0.84)  LDD2162  [10]
 LDCM0622  AC155 HEK-293T C1307(0.73)  LDD2163  [10]
 LDCM0623  AC156 HEK-293T C1307(0.87)  LDD2164  [10]
 LDCM0624  AC157 HEK-293T C1307(0.77)  LDD2165  [10]
 LDCM0276  AC17 HEK-293T C1428(0.91)  LDD0874  [10]
 LDCM0277  AC18 HEK-293T C1428(0.87)  LDD0875  [10]
 LDCM0278  AC19 HEK-293T C1428(0.91)  LDD0876  [10]
 LDCM0279  AC2 HEK-293T C1080(1.10); C756(0.95); C299(0.97); C585(0.90)  LDD1518  [9]
 LDCM0280  AC20 HEK-293T C1428(0.93)  LDD0878  [10]
 LDCM0281  AC21 HEK-293T C1428(0.97)  LDD0879  [10]
 LDCM0282  AC22 HEK-293T C1428(0.86)  LDD0880  [10]
 LDCM0283  AC23 HEK-293T C1428(0.89)  LDD0881  [10]
 LDCM0284  AC24 HEK-293T C1428(0.98)  LDD0882  [10]
 LDCM0285  AC25 HEK-293T C1307(0.87)  LDD0883  [10]
 LDCM0286  AC26 HEK-293T C1307(0.77)  LDD0884  [10]
 LDCM0287  AC27 HEK-293T C1307(0.77)  LDD0885  [10]
 LDCM0288  AC28 HEK-293T C1307(0.74)  LDD0886  [10]
 LDCM0289  AC29 HEK-293T C1307(0.77)  LDD0887  [10]
 LDCM0290  AC3 HEK-293T C756(1.46); C299(0.91); C1077(0.99); C1089(1.06)  LDD1529  [9]
 LDCM0291  AC30 HEK-293T C1307(0.80)  LDD0889  [10]
 LDCM0292  AC31 HEK-293T C1307(0.95)  LDD0890  [10]
 LDCM0293  AC32 HEK-293T C1307(0.93)  LDD0891  [10]
 LDCM0294  AC33 HEK-293T C1307(0.76)  LDD0892  [10]
 LDCM0295  AC34 HEK-293T C1307(0.91)  LDD0893  [10]
 LDCM0296  AC35 HEK-293T C756(1.12); C299(0.97); C1077(1.05); C1089(0.75)  LDD1535  [9]
 LDCM0297  AC36 HEK-293T C158(1.10); C756(0.84); C299(0.99); C1089(1.01)  LDD1536  [9]
 LDCM0298  AC37 HEK-293T C158(0.96); C299(0.90); C1307(0.95); C101(0.99)  LDD1537  [9]
 LDCM0299  AC38 HEK-293T C1080(1.06); C756(1.01); C299(1.21); C1428(1.10)  LDD1538  [9]
 LDCM0300  AC39 HEK-293T C158(0.98); C756(0.98); C299(1.06); C1307(1.06)  LDD1539  [9]
 LDCM0301  AC4 HEK-293T C158(1.11); C756(1.01); C299(0.95); C1089(0.94)  LDD1540  [9]
 LDCM0302  AC40 HEK-293T C1080(0.94); C756(1.24); C299(1.00); C585(0.76)  LDD1541  [9]
 LDCM0303  AC41 HEK-293T C158(1.09); C1016(1.02); C1307(0.87); C101(0.98)  LDD1542  [9]
 LDCM0304  AC42 HEK-293T C1080(1.07); C756(1.37); C299(1.08); C585(0.97)  LDD1543  [9]
 LDCM0305  AC43 HEK-293T C756(1.51); C299(1.06); C1077(1.02); C1089(1.04)  LDD1544  [9]
 LDCM0306  AC44 HEK-293T C158(1.15); C756(1.02); C299(0.93); C1089(1.11)  LDD1545  [9]
 LDCM0307  AC45 HEK-293T C158(1.05); C299(0.87); C1307(1.03); C101(0.98)  LDD1546  [9]
 LDCM0308  AC46 HEK-293T C1307(0.97)  LDD0906  [10]
 LDCM0309  AC47 HEK-293T C1307(0.75)  LDD0907  [10]
 LDCM0310  AC48 HEK-293T C1307(0.67)  LDD0908  [10]
 LDCM0311  AC49 HEK-293T C1307(0.66)  LDD0909  [10]
 LDCM0312  AC5 HEK-293T C158(0.97); C299(0.89); C1307(0.98); C101(0.96)  LDD1551  [9]
 LDCM0313  AC50 HEK-293T C1307(0.66)  LDD0911  [10]
 LDCM0314  AC51 HEK-293T C1307(0.59)  LDD0912  [10]
 LDCM0315  AC52 HEK-293T C1307(0.56)  LDD0913  [10]
 LDCM0316  AC53 HEK-293T C1307(0.71)  LDD0914  [10]
 LDCM0317  AC54 HEK-293T C1307(0.63)  LDD0915  [10]
 LDCM0318  AC55 HEK-293T C1307(0.68)  LDD0916  [10]
 LDCM0319  AC56 HEK-293T C1307(0.78)  LDD0917  [10]
 LDCM0320  AC57 HEK-293T C158(1.06); C1016(0.98); C1307(0.97); C101(1.13)  LDD1559  [9]
 LDCM0321  AC58 HEK-293T C1080(1.00); C756(1.07); C299(1.00); C585(0.85)  LDD1560  [9]
 LDCM0322  AC59 HEK-293T C756(1.09); C299(0.93); C1077(0.95); C1089(1.00)  LDD1561  [9]
 LDCM0323  AC6 HEK-293T C1428(1.27)  LDD0921  [10]
 LDCM0324  AC60 HEK-293T C158(1.08); C756(0.91); C299(1.03); C1089(1.25)  LDD1563  [9]
 LDCM0325  AC61 HEK-293T C158(1.09); C299(1.02); C1307(1.02); C101(1.01)  LDD1564  [9]
 LDCM0326  AC62 HEK-293T C1080(1.08); C756(0.96); C299(1.15); C1428(0.95)  LDD1565  [9]
 LDCM0327  AC63 HEK-293T C158(0.94); C756(0.90); C299(1.02); C1307(1.06)  LDD1566  [9]
 LDCM0328  AC64 HEK-293T C1080(1.07); C756(0.98); C299(1.07); C585(0.74)  LDD1567  [9]
 LDCM0332  AC68 HEK-293T C765(0.93)  LDD0930  [10]
 LDCM0333  AC69 HEK-293T C765(0.87)  LDD0931  [10]
 LDCM0334  AC7 HEK-293T C1428(1.15)  LDD0932  [10]
 LDCM0335  AC70 HEK-293T C765(0.76)  LDD0933  [10]
 LDCM0336  AC71 HEK-293T C765(0.74)  LDD0934  [10]
 LDCM0337  AC72 HEK-293T C765(0.74)  LDD0935  [10]
 LDCM0338  AC73 HEK-293T C765(0.74)  LDD0936  [10]
 LDCM0339  AC74 HEK-293T C765(0.60)  LDD0937  [10]
 LDCM0340  AC75 HEK-293T C765(0.57)  LDD0938  [10]
 LDCM0341  AC76 HEK-293T C765(0.78)  LDD0939  [10]
 LDCM0342  AC77 HEK-293T C765(0.63)  LDD0940  [10]
 LDCM0343  AC78 HEK-293T C765(0.70)  LDD0941  [10]
 LDCM0344  AC79 HEK-293T C765(0.82)  LDD0942  [10]
 LDCM0345  AC8 HEK-293T C1428(1.03)  LDD0943  [10]
 LDCM0346  AC80 HEK-293T C765(0.59)  LDD0944  [10]
 LDCM0347  AC81 HEK-293T C765(0.56)  LDD0945  [10]
 LDCM0348  AC82 HEK-293T C765(0.58)  LDD0946  [10]
 LDCM0349  AC83 HEK-293T C1307(1.27)  LDD0947  [10]
 LDCM0350  AC84 HEK-293T C1307(0.77)  LDD0948  [10]
 LDCM0351  AC85 HEK-293T C1307(0.83)  LDD0949  [10]
 LDCM0352  AC86 HEK-293T C1307(0.89)  LDD0950  [10]
 LDCM0353  AC87 HEK-293T C1307(0.96)  LDD0951  [10]
 LDCM0354  AC88 HEK-293T C1307(0.82)  LDD0952  [10]
 LDCM0355  AC89 HEK-293T C1307(0.72)  LDD0953  [10]
 LDCM0357  AC90 HEK-293T C1307(0.68)  LDD0955  [10]
 LDCM0358  AC91 HEK-293T C1307(0.80)  LDD0956  [10]
 LDCM0359  AC92 HEK-293T C1307(0.89)  LDD0957  [10]
 LDCM0360  AC93 HEK-293T C1307(0.76)  LDD0958  [10]
 LDCM0361  AC94 HEK-293T C1307(0.70)  LDD0959  [10]
 LDCM0362  AC95 HEK-293T C1307(0.85)  LDD0960  [10]
 LDCM0363  AC96 HEK-293T C1307(0.66)  LDD0961  [10]
 LDCM0364  AC97 HEK-293T C1307(0.67)  LDD0962  [10]
 LDCM0365  AC98 HEK-293T C1428(1.07); C765(0.95)  LDD0963  [10]
 LDCM0366  AC99 HEK-293T C1428(1.07); C765(1.10)  LDD0964  [10]
 LDCM0248  AKOS034007472 HEK-293T C1428(1.15)  LDD0846  [10]
 LDCM0356  AKOS034007680 HEK-293T C1428(1.11)  LDD0954  [10]
 LDCM0275  AKOS034007705 HEK-293T C1428(1.28)  LDD0873  [10]
 LDCM0367  CL1 HEK-293T C1080(1.06); C158(1.44); C101(1.03); C1089(1.02)  LDD1571  [9]
 LDCM0368  CL10 HEK-293T C1080(1.01); C756(1.20); C299(1.34); C1428(0.87)  LDD1572  [9]
 LDCM0369  CL100 HEK-293T C158(0.94); C756(0.98); C299(0.96); C1016(1.04)  LDD1573  [9]
 LDCM0370  CL101 HEK-293T C1428(1.18)  LDD0968  [10]
 LDCM0371  CL102 HEK-293T C1428(1.09)  LDD0969  [10]
 LDCM0372  CL103 HEK-293T C1428(1.02)  LDD0970  [10]
 LDCM0373  CL104 HEK-293T C1428(0.94)  LDD0971  [10]
 LDCM0374  CL105 HEK-293T C1428(0.98)  LDD0972  [10]
 LDCM0375  CL106 HEK-293T C1428(0.94)  LDD0973  [10]
 LDCM0376  CL107 HEK-293T C1428(0.92)  LDD0974  [10]
 LDCM0377  CL108 HEK-293T C1428(0.89)  LDD0975  [10]
 LDCM0378  CL109 HEK-293T C1428(0.89)  LDD0976  [10]
 LDCM0379  CL11 HEK-293T C158(1.19); C756(0.94); C299(1.02); C1307(1.23)  LDD1583  [9]
 LDCM0380  CL110 HEK-293T C1428(0.90)  LDD0978  [10]
 LDCM0381  CL111 HEK-293T C1428(0.87)  LDD0979  [10]
 LDCM0382  CL112 HEK-293T C1307(0.72)  LDD0980  [10]
 LDCM0383  CL113 HEK-293T C1307(0.91)  LDD0981  [10]
 LDCM0384  CL114 HEK-293T C1307(0.65)  LDD0982  [10]
 LDCM0385  CL115 HEK-293T C1307(0.71)  LDD0983  [10]
 LDCM0386  CL116 HEK-293T C1307(0.74)  LDD0984  [10]
 LDCM0387  CL117 HEK-293T C1080(1.00); C158(1.04); C101(1.14); C1089(1.00)  LDD1591  [9]
 LDCM0388  CL118 HEK-293T C756(1.34); C585(1.14); C101(1.05)  LDD1592  [9]
 LDCM0389  CL119 HEK-293T C158(1.12); C1089(1.34); C105(0.97)  LDD1593  [9]
 LDCM0390  CL12 HEK-293T C1080(1.19); C756(1.37); C299(1.12); C585(0.98)  LDD1594  [9]
 LDCM0391  CL120 HEK-293T C158(0.85); C756(1.37); C299(1.00); C1016(1.07)  LDD1595  [9]
 LDCM0392  CL121 HEK-293T C1307(0.63)  LDD0990  [10]
 LDCM0393  CL122 HEK-293T C1307(0.67)  LDD0991  [10]
 LDCM0394  CL123 HEK-293T C1307(0.64)  LDD0992  [10]
 LDCM0395  CL124 HEK-293T C1307(0.68)  LDD0993  [10]
 LDCM0396  CL125 HEK-293T C1080(1.01); C158(1.06); C101(0.95); C1089(1.04)  LDD1600  [9]
 LDCM0397  CL126 HEK-293T C756(1.24); C585(1.17); C101(0.96)  LDD1601  [9]
 LDCM0398  CL127 HEK-293T C158(0.96); C1089(1.02); C105(1.05)  LDD1602  [9]
 LDCM0399  CL128 HEK-293T C158(0.88); C756(0.86); C299(0.85); C1016(1.05)  LDD1603  [9]
 LDCM0400  CL13 HEK-293T C1080(1.01); C158(1.27); C101(0.97); C1089(1.08)  LDD1604  [9]
 LDCM0401  CL14 HEK-293T C756(1.13); C585(1.22); C101(0.91)  LDD1605  [9]
 LDCM0402  CL15 HEK-293T C158(1.09); C1089(1.21); C105(1.09)  LDD1606  [9]
 LDCM0403  CL16 HEK-293T C1307(1.21)  LDD1001  [10]
 LDCM0404  CL17 HEK-293T C1307(1.11)  LDD1002  [10]
 LDCM0405  CL18 HEK-293T C1307(0.87)  LDD1003  [10]
 LDCM0406  CL19 HEK-293T C1307(0.88)  LDD1004  [10]
 LDCM0407  CL2 HEK-293T C756(1.01); C585(1.05); C101(0.95)  LDD1611  [9]
 LDCM0408  CL20 HEK-293T C1307(0.91)  LDD1006  [10]
 LDCM0409  CL21 HEK-293T C1307(0.85)  LDD1007  [10]
 LDCM0410  CL22 HEK-293T C1307(0.94)  LDD1008  [10]
 LDCM0411  CL23 HEK-293T C1307(0.92)  LDD1009  [10]
 LDCM0412  CL24 HEK-293T C1307(0.96)  LDD1010  [10]
 LDCM0413  CL25 HEK-293T C1307(0.91)  LDD1011  [10]
 LDCM0414  CL26 HEK-293T C1307(0.88)  LDD1012  [10]
 LDCM0415  CL27 HEK-293T C1307(0.89)  LDD1013  [10]
 LDCM0416  CL28 HEK-293T C1307(0.96)  LDD1014  [10]
 LDCM0417  CL29 HEK-293T C1307(1.05)  LDD1015  [10]
 LDCM0418  CL3 HEK-293T C158(1.20); C1089(1.05); C105(1.12)  LDD1622  [9]
 LDCM0419  CL30 HEK-293T C1307(0.78)  LDD1017  [10]
 LDCM0420  CL31 HEK-293T C1428(0.99); C765(0.83)  LDD1018  [10]
 LDCM0421  CL32 HEK-293T C1428(0.94); C765(0.60)  LDD1019  [10]
 LDCM0422  CL33 HEK-293T C1428(0.78); C765(0.50)  LDD1020  [10]
 LDCM0423  CL34 HEK-293T C1428(1.02); C765(0.97)  LDD1021  [10]
 LDCM0424  CL35 HEK-293T C1428(0.89); C765(0.61)  LDD1022  [10]
 LDCM0425  CL36 HEK-293T C1428(0.96); C765(0.66)  LDD1023  [10]
 LDCM0426  CL37 HEK-293T C1428(0.98); C765(0.63)  LDD1024  [10]
 LDCM0428  CL39 HEK-293T C1428(1.05); C765(0.87)  LDD1026  [10]
 LDCM0429  CL4 HEK-293T C158(1.26); C756(0.71); C299(0.93); C1016(1.15)  LDD1633  [9]
 LDCM0430  CL40 HEK-293T C1428(0.96); C765(0.71)  LDD1028  [10]
 LDCM0431  CL41 HEK-293T C1428(0.95); C765(0.91)  LDD1029  [10]
 LDCM0432  CL42 HEK-293T C1428(0.95); C765(0.94)  LDD1030  [10]
 LDCM0433  CL43 HEK-293T C1428(0.90); C765(0.70)  LDD1031  [10]
 LDCM0434  CL44 HEK-293T C1428(0.96); C765(0.72)  LDD1032  [10]
 LDCM0435  CL45 HEK-293T C1428(0.90); C765(0.69)  LDD1033  [10]
 LDCM0436  CL46 HEK-293T C1080(1.07); C756(1.19); C299(1.08); C1428(1.03)  LDD1640  [9]
 LDCM0437  CL47 HEK-293T C158(1.29); C756(0.99); C299(1.05); C1307(1.02)  LDD1641  [9]
 LDCM0438  CL48 HEK-293T C1080(1.05); C756(1.15); C299(1.05); C585(1.04)  LDD1642  [9]
 LDCM0439  CL49 HEK-293T C1080(1.09); C158(1.11); C101(1.05); C1089(0.99)  LDD1643  [9]
 LDCM0440  CL5 HEK-293T C158(1.13); C1016(0.85); C1307(1.06); C101(1.01)  LDD1644  [9]
 LDCM0441  CL50 HEK-293T C756(1.09); C585(1.13); C101(0.95)  LDD1645  [9]
 LDCM0443  CL52 HEK-293T C158(0.98); C756(0.86); C299(1.05); C1016(1.17)  LDD1646  [9]
 LDCM0444  CL53 HEK-293T C158(1.32); C1016(0.99); C1307(1.20); C101(0.99)  LDD1647  [9]
 LDCM0445  CL54 HEK-293T C1080(1.01); C756(1.13); C299(0.94); C585(1.00)  LDD1648  [9]
 LDCM0446  CL55 HEK-293T C756(1.01); C299(1.10); C1077(1.02); C1089(1.08)  LDD1649  [9]
 LDCM0447  CL56 HEK-293T C158(1.17); C756(0.94); C299(0.97); C1089(1.00)  LDD1650  [9]
 LDCM0448  CL57 HEK-293T C158(1.40); C299(1.09); C1307(1.22); C101(1.10)  LDD1651  [9]
 LDCM0449  CL58 HEK-293T C1080(1.15); C756(1.11); C299(1.26); C1428(1.03)  LDD1652  [9]
 LDCM0450  CL59 HEK-293T C158(1.04); C756(1.24); C299(1.05); C1307(1.06)  LDD1653  [9]
 LDCM0451  CL6 HEK-293T C1080(0.99); C756(1.02); C299(0.98); C585(1.16)  LDD1654  [9]
 LDCM0452  CL60 HEK-293T C1080(1.07); C756(1.30); C299(0.94); C585(1.02)  LDD1655  [9]
 LDCM0453  CL61 HEK-293T C1080(0.94); C158(0.97); C101(1.04); C1089(1.06)  LDD1656  [9]
 LDCM0454  CL62 HEK-293T C756(1.38); C585(1.00); C101(0.94)  LDD1657  [9]
 LDCM0455  CL63 HEK-293T C158(1.07); C1089(1.10); C105(1.03)  LDD1658  [9]
 LDCM0456  CL64 HEK-293T C158(0.98); C756(1.19); C299(1.02); C1016(1.19)  LDD1659  [9]
 LDCM0457  CL65 HEK-293T C158(1.16); C1016(0.93); C1307(0.78); C101(0.98)  LDD1660  [9]
 LDCM0458  CL66 HEK-293T C1080(1.01); C756(1.16); C299(1.08); C585(0.97)  LDD1661  [9]
 LDCM0459  CL67 HEK-293T C756(1.09); C299(0.93); C1077(1.14); C1089(0.95)  LDD1662  [9]
 LDCM0460  CL68 HEK-293T C158(1.18); C756(1.00); C299(1.05); C1089(0.91)  LDD1663  [9]
 LDCM0461  CL69 HEK-293T C158(1.23); C299(1.00); C1307(1.08); C101(0.94)  LDD1664  [9]
 LDCM0462  CL7 HEK-293T C756(0.89); C299(1.03); C1077(1.01); C1089(0.91)  LDD1665  [9]
 LDCM0463  CL70 HEK-293T C1080(1.07); C756(0.92); C299(1.15); C1428(1.02)  LDD1666  [9]
 LDCM0464  CL71 HEK-293T C158(1.07); C756(0.97); C299(0.98); C1307(1.00)  LDD1667  [9]
 LDCM0465  CL72 HEK-293T C1080(1.11); C756(0.85); C299(1.06); C585(1.15)  LDD1668  [9]
 LDCM0466  CL73 HEK-293T C1080(0.95); C158(1.09); C101(0.96); C1089(0.95)  LDD1669  [9]
 LDCM0467  CL74 HEK-293T C756(1.22); C585(1.04); C101(0.97)  LDD1670  [9]
 LDCM0469  CL76 HEK-293T C1307(0.82)  LDD1067  [10]
 LDCM0470  CL77 HEK-293T C1307(0.77)  LDD1068  [10]
 LDCM0471  CL78 HEK-293T C1307(0.72)  LDD1069  [10]
 LDCM0472  CL79 HEK-293T C1307(0.74)  LDD1070  [10]
 LDCM0473  CL8 HEK-293T C158(1.88); C756(1.10); C299(0.95); C1089(0.94)  LDD1676  [9]
 LDCM0474  CL80 HEK-293T C1307(0.82)  LDD1072  [10]
 LDCM0475  CL81 HEK-293T C1307(0.86)  LDD1073  [10]
 LDCM0476  CL82 HEK-293T C1307(1.04)  LDD1074  [10]
 LDCM0477  CL83 HEK-293T C1307(0.95)  LDD1075  [10]
 LDCM0478  CL84 HEK-293T C1307(0.91)  LDD1076  [10]
 LDCM0479  CL85 HEK-293T C1307(0.71)  LDD1077  [10]
 LDCM0480  CL86 HEK-293T C1307(0.55)  LDD1078  [10]
 LDCM0481  CL87 HEK-293T C1307(0.72)  LDD1079  [10]
 LDCM0482  CL88 HEK-293T C1307(0.83)  LDD1080  [10]
 LDCM0483  CL89 HEK-293T C1307(0.79)  LDD1081  [10]
 LDCM0484  CL9 HEK-293T C158(1.21); C299(0.95); C1307(1.31); C101(1.00)  LDD1687  [9]
 LDCM0485  CL90 HEK-293T C1307(0.81)  LDD1083  [10]
 LDCM0486  CL91 HEK-293T C756(0.98); C299(1.05); C1077(0.91); C1089(1.05)  LDD1689  [9]
 LDCM0487  CL92 HEK-293T C158(1.19); C756(0.91); C299(0.96); C1089(1.08)  LDD1690  [9]
 LDCM0488  CL93 HEK-293T C158(1.22); C299(0.99); C1307(1.47); C101(0.98)  LDD1691  [9]
 LDCM0489  CL94 HEK-293T C1080(1.05); C756(0.85); C299(1.09); C1428(0.93)  LDD1692  [9]
 LDCM0490  CL95 HEK-293T C158(1.15); C756(1.12); C299(0.92); C1307(2.09)  LDD1693  [9]
 LDCM0491  CL96 HEK-293T C1080(0.94); C756(1.03); C299(1.07); C585(0.91)  LDD1694  [9]
 LDCM0492  CL97 HEK-293T C1080(0.96); C158(0.96); C101(0.97); C1089(1.03)  LDD1695  [9]
 LDCM0493  CL98 HEK-293T C756(1.04); C585(1.06); C101(0.99)  LDD1696  [9]
 LDCM0494  CL99 HEK-293T C158(0.97); C1089(1.09); C105(1.06)  LDD1697  [9]
 LDCM0495  E2913 HEK-293T C158(1.07); C1089(1.13); C105(1.23)  LDD1698  [9]
 LDCM0468  Fragment33 HEK-293T C158(1.15); C1089(1.07); C105(1.07)  LDD1671  [9]
 LDCM0427  Fragment51 HEK-293T C1428(0.94); C765(0.51)  LDD1025  [10]
 LDCM0022  KB02 HEK-293T C158(1.06)  LDD1492  [9]
 LDCM0023  KB03 HEK-293T C158(0.99)  LDD1497  [9]
 LDCM0024  KB05 COLO792 C933(5.43)  LDD3310  [2]
 LDCM0109  NEM HeLa N.A.  LDD0231  [4]

References

1 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
5 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
6 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
7 Differently Tagged Probes for Protein Profiling of Mitochondria. Chembiochem. 2019 May 2;20(9):1155-1160. doi: 10.1002/cbic.201800735. Epub 2019 Mar 26.
8 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
10 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.