Details of the Probe

General Information of Probe

Probe ID
LDPC0410
Probe Name
C170
Synonyms
Z4282860420
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 350.5
Lipid-water partition coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C21H26N4O
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-1-[4-(pyrrolidin-1-ylmethyl)-2,3-dihydroindol-1-yl]propan-1-one
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)N2CCC3=C(C=CC=C32)CN4CCCC4
InChI
InChI=1S/C21H26N4O/c1-2-3-11-21(22-23-21)12-9-20(26)25-15-10-18-17(7-6-8-19(18)25)16-24-13-4-5-14-24/h1,6-8H,3-5,9-16H2
InChIKey
JKWINQQYLNKDEU-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

117 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
5'-3' exonuclease PLD3 (PLD3) LDTP08476 33.36  LDD1850 
Acid ceramidase (ASAH1) LDTP05905 30.91  LDD1850 
Acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B) LDTP09764 14.93  LDD1850 
Adenylate cyclase type 3 (ADCY3) LDTP00932 10.34  LDD1850 
Alpha-galactosidase A (GLA) LDTP02141 37.01  LDD1850 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 32.67  LDD1850 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 8.17  LDD1850 
Arylsulfatase A (ARSA) LDTP02776 11.31  LDD1850 
Beta-1,4-galactosyltransferase 3 (B4GALT3) LDTP00994 16.45  LDD1850 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 14.32  LDD1850 
Beta-galactosidase (GLB1) LDTP02837 33.13  LDD1850 
Beta-glucuronidase (GUSB) LDTP02260 28.44  LDD1850 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 31.56  LDD1850 
Beta-hexosaminidase subunit beta (HEXB) LDTP02216 29.65  LDD1850 
Beta-mannosidase (MANBA) LDTP00282 30.27  LDD1850 
Bis(5'-adenosyl)-triphosphatase ENPP4 (ENPP4) LDTP14305 20.82  LDD1850 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 34.06  LDD1850 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 8.82  LDD1850 
cAMP-dependent protein kinase catalytic subunit beta (PRKACB) LDTP03188 7.36  LDD1850 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 8.94  LDD1850 
Carboxypeptidase D (CPD) LDTP01372 36.00  LDD1850 
Carboxypeptidase E (CPE) LDTP02865 12.21  LDD1850 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 13.36  LDD1850 
Cathepsin B (CTSB) LDTP02223 50.56  LDD1850 
Cathepsin F (CTSF) LDTP13172 11.96  LDD1850 
Ceramide glucosyltransferase (UGCG) LDTP06617 20.97  LDD1850 
Ceramide synthase 2 (CERS2) LDTP10329 9.58  LDD1850 
Choline kinase alpha (CHKA) LDTP03787 8.46  LDD1850 
Chondroitin sulfate glucuronyltransferase (CHPF2) LDTP13042 8.11  LDD1850 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) LDTP08933 19.70  LDD1850 
Cyclic GMP-AMP phosphodiesterase SMPDL3A (SMPDL3A) LDTP09763 11.16  LDD1850 
Cytochrome b5 type B (CYB5B) LDTP00697 31.34  LDD1850 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 24.42  LDD1850 
Delta(24)-sterol reductase (DHCR24) LDTP06375 24.08  LDD1850 
Deoxyribonuclease-2-alpha (DNASE2) LDTP00185 39.12  LDD1850 
Di-N-acetylchitobiase (CTBS) LDTP14801 27.47  LDD1850 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 32.45  LDD1850 
E3 ubiquitin-protein ligase MGRN1 (MGRN1) LDTP00939 8.06  LDD1850 
E3 ubiquitin-protein ligase RNF149 (RNF149) LDTP09079 14.42  LDD1850 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 7.78  LDD1850 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 19.03  LDD1850 
Ephrin type-A receptor 2 (EPHA2) LDTP03474 9.06  LDD1850 
Ephrin type-A receptor 7 (EPHA7) LDTP06370 16.00  LDD1850 
Epidermal growth factor receptor (EGFR) LDTP01785 7.36  LDD1850 
Ethylmalonyl-CoA decarboxylase (ECHDC1) LDTP16095 7.78  LDD1850 
Exonuclease 1 (EXO1) LDTP13751 8.51  LDD1850 
Ferrochelatase, mitochondrial (FECH) LDTP03198 12.73  LDD1850 
Gamma-glutamyl hydrolase (GGH) LDTP09886 29.24  LDD1850 
Glutathione hydrolase 7 (GGT7) LDTP13367 8.17  LDD1850 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 15.14  LDD1850 
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) LDTP04032 7.62  LDD1850 
Glycoprotein endo-alpha-1,2-mannosidase (MANEA) LDTP14993 8.22  LDD1850 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 13.18  LDD1850 
Heme oxygenase 2 (HMOX2) LDTP03540 7.52  LDD1850 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 12.55  LDD1850 
Histone deacetylase complex subunit SAP130 (SAP130) LDTP11703 7.84  LDD1850 
Histone lysine demethylase PHF8 (PHF8) LDTP13703 10.48  LDD1850 
Histone-lysine N-methyltransferase EHMT1 (EHMT1) LDTP12089 9.71  LDD1850 
Histone-lysine N-methyltransferase EHMT2 (EHMT2) LDTP10517 9.85  LDD1850 
Holocytochrome c-type synthase (HCCS) LDTP04581 8.28  LDD1850 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 8.57  LDD1850 
Lactadherin (MFGE8) LDTP05561 17.27  LDD1850 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 10.41  LDD1850 
Legumain (LGMN) LDTP10888 33.59  LDD1850 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 33.59  LDD1850 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 18.13  LDD1850 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 12.64  LDD1850 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 10.34  LDD1850 
Lysosomal acid phosphatase (ACP2) LDTP02539 33.82  LDD1850 
Lysosomal alpha-glucosidase (GAA) LDTP02486 30.27  LDD1850 
Lysosomal alpha-mannosidase (MAN2B1) LDTP00338 18.64  LDD1850 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 14.12  LDD1850 
Lysosomal protective protein (CTSA) LDTP02505 27.67  LDD1850 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 68.59  LDD1850 
Macrophage migration inhibitory factor (MIF) LDTP02713 7.62  LDD1850 
Myotubularin-related protein 4 (MTMR4) LDTP12819 11.31  LDD1850 
N-acetylgalactosamine-6-sulfatase (GALNS) LDTP03683 33.13  LDD1850 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 37.01  LDD1850 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 8.28  LDD1850 
N-sulphoglucosamine sulphohydrolase (SGSH) LDTP04452 9.32  LDD1850 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 7.46  LDD1850 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 21.56  LDD1850 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 8.75  LDD1850 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 8.94  LDD1850 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 32.90  LDD1850 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 11.08  LDD1850 
Peptidyl-glycine alpha-amidating monooxygenase (PAM) LDTP02976 34.06  LDD1850 
Peroxisomal leader peptide-processing protease (TYSND1) LDTP06720 8.51  LDD1850 
Phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) LDTP11209 7.46  LDD1850 
Phosphatidylinositol 4-kinase type 2-beta (PI4K2B) LDTP09384 8.22  LDD1850 
Phospholipase A2 group XV (PLA2G15) LDTP09088 20.39  LDD1850 
Phosphorylase b kinase regulatory subunit beta (PHKB) LDTP09984 7.94  LDD1850 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 41.93  LDD1850 
Polyamine-transporting ATPase 13A3 (ATP13A3) LDTP12026 10.70  LDD1850 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 11.55  LDD1850 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 21.71  LDD1850 
Procathepsin L (CTSL) LDTP02217 55.33  LDD1850 
Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 11.31  LDD1850 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 43.11  LDD1850 
Receptor-type tyrosine-protein phosphatase F (PTPRF) LDTP02499 8.82  LDD1850 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 48.84  LDD1850 
Ribitol 5-phosphate transferase FKRP (FKRP) LDTP12109 7.67  LDD1850 
Ribonuclease T2 (RNASET2) LDTP00316 42.81  LDD1850 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 9.25  LDD1850 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PPP2R5E) LDTP06546 9.71  LDD1850 
Sialate O-acetylesterase (SIAE) LDTP12135 54.19  LDD1850 
Sialidase-1 (NEU1) LDTP10884 19.16  LDD1850 
Soluble calcium-activated nucleotidase 1 (CANT1) LDTP09620 9.19  LDD1850 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 19.16  LDD1850 
Thioredoxin domain-containing protein 16 (TXNDC16) LDTP13058 12.55  LDD1850 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 19.97  LDD1850 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 11.79  LDD1850 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 94.35  LDD1850 
Tyrosine-protein kinase JAK1 (JAK1) LDTP03230 7.36  LDD1850 
UDP-glucuronic acid decarboxylase 1 (UXS1) LDTP09074 15.89  LDD1850 
Uracil-DNA glycosylase (UNG) LDTP02643 22.32  LDD1850 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 7.31  LDD1850 
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⏷ Show the Full List of 117 Enzyme
72 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 7.52  LDD1850 
Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 7.89  LDD1850 
Amyloid-beta precursor protein (APP) LDTP02071 35.75  LDD1850 
Autophagy-related protein 9A (ATG9A) LDTP08030 7.52  LDD1850 
Cation-dependent mannose-6-phosphate receptor (M6PR) LDTP03061 8.11  LDD1850 
Cation-independent mannose-6-phosphate receptor (IGF2R) LDTP02586 28.44  LDD1850 
Cell cycle control protein 50A (TMEM30A) LDTP12665 8.82  LDD1850 
Cochlin (COCH) LDTP00761 11.39  LDD1850 
Dystroglycan 1 (DAG1) LDTP06039 12.55  LDD1850 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 10.48  LDD1850 
Flotillin-1 (FLOT1) LDTP01366 7.36  LDD1850 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 31.12  LDD1850 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 9.99  LDD1850 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 15.45  LDD1850 
Integral membrane protein 2B (ITM2B) LDTP13833 42.22  LDD1850 
Integral membrane protein 2C (ITM2C) LDTP12451 23.26  LDD1850 
Low-density lipoprotein receptor (LDLR) LDTP01829 25.63  LDD1850 
Low-density lipoprotein receptor-related protein 2 (LRP2) LDTP05218 26.54  LDD1850 
Lysosome membrane protein 2 (SCARB2) LDTP06034 27.47  LDD1850 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 20.39  LDD1850 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 40.50  LDD1850 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 11.16  LDD1850 
Major facilitator superfamily domain-containing protein 8 (MFSD8) LDTP09261 15.03  LDD1850 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 8.46  LDD1850 
Metal transporter CNNM3 (CNNM3) LDTP09144 9.32  LDD1850 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 17.88  LDD1850 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 7.94  LDD1850 
Neuropilin-1 (NRP1) LDTP00433 8.69  LDD1850 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 15.03  LDD1850 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 31.34  LDD1850 
Occludin (OCLN) LDTP06581 13.55  LDD1850 
Osteopetrosis-associated transmembrane protein 1 (OSTM1) LDTP08327 26.91  LDD1850 
Podocalyxin (PODXL) LDTP00321 16.34  LDD1850 
Prolow-density lipoprotein receptor-related protein 1 (LRP1) LDTP05538 15.14  LDD1850 
Prosaposin (PSAP) LDTP02215 37.79  LDD1850 
Protein ARV1 (ARV1) LDTP11812 8.82  LDD1850 
Protein GPR107 (GPR107) LDTP07236 11.96  LDD1850 
Protein GPR108 (GPR108) LDTP12383 7.94  LDD1850 
Protein tweety homolog 3 (TTYH3) LDTP11615 38.59  LDD1850 
Proton-activated chloride channel (PACC1) LDTP12042 26.17  LDD1850 
Reduced folate transporter (SLC19A1) LDTP03952 7.84  LDD1850 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 12.21  LDD1850 
Slit homolog 2 protein (SLIT2) LDTP01427 16.68  LDD1850 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 7.62  LDD1850 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 13.45  LDD1850 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 16.91  LDD1850 
Sodium/hydrogen exchanger 6 (SLC9A6) LDTP09807 15.14  LDD1850 
Solute carrier family 12 member 9 (SLC12A9) LDTP11397 8.00  LDD1850 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 9.38  LDD1850 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 7.67  LDD1850 
Sortilin (SORT1) LDTP10885 14.52  LDD1850 
Sortilin-related receptor (SORL1) LDTP09838 29.65  LDD1850 
Stomatin (STOM) LDTP03380 18.00  LDD1850 
Sugar phosphate exchanger 3 (SLC37A3) LDTP09089 11.08  LDD1850 
Surfeit locus protein 4 (SURF4) LDTP00592 10.06  LDD1850 
Syntaxin-6 (STX6) LDTP00857 18.38  LDD1850 
Syntenin-1 (SDCBP) LDTP00310 15.67  LDD1850 
Tetraspanin-3 (TSPAN3) LDTP16813 24.08  LDD1850 
Transferrin receptor protein 1 (TFRC) LDTP01969 21.41  LDD1850 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 12.55  LDD1850 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 10.63  LDD1850 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 11.00  LDD1850 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 11.47  LDD1850 
Transmembrane protein 106B (TMEM106B) LDTP12635 24.25  LDD1850 
Transmembrane protein 192 (TMEM192) LDTP08633 7.41  LDD1850 
Transmembrane protein 199 (TMEM199) LDTP08881 8.06  LDD1850 
Transmembrane protein 59 (TMEM59) LDTP11406 99.73  LDD1850 
Transmembrane protein 87A (TMEM87A) LDTP15481 21.26  LDD1850 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 7.62  LDD1850 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 13.45  LDD1850 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 18.51  LDD1850 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 17.27  LDD1850 
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⏷ Show the Full List of 72 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Attractin (ATRN) LDTP01337 15.14  LDD1850 
Y-box-binding protein 1 (YBX1) LDTP05065 8.82  LDD1850 
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1 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adhesion G protein-coupled receptor E5 (ADGRE5) LDTP04221 11.79  LDD1850 
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11 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Butyrophilin subfamily 2 member A1 (BTN2A1) LDTP07927 10.34  LDD1850 
Coxsackievirus and adenovirus receptor (CXADR) LDTP05085 7.89  LDD1850 
HLA class I histocompatibility antigen, A alpha chain (HLA-A) LDTP02040 24.93  LDD1850 
HLA class I histocompatibility antigen, B alpha chain (HLA-B) LDTP01913 14.03  LDD1850 
HLA class I histocompatibility antigen, C alpha chain (HLA-C) LDTP02491 17.27  LDD1850 
IgG receptor FcRn large subunit p51 (FCGRT) LDTP04720 31.34  LDD1850 
Junctional adhesion molecule A (F11R) LDTP14203 11.88  LDD1850 
Leukocyte surface antigen CD47 (CD47) LDTP05572 8.94  LDD1850 
Nectin-2 (NECTIN2) LDTP09844 7.62  LDD1850 
Neogenin (NEO1) LDTP09907 8.17  LDD1850 
Roundabout homolog 1 (ROBO1) LDTP14280 15.03  LDD1850 
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⏷ Show the Full List of 11 Immunoglobulin
1 Cytokine and receptor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Interferon gamma receptor 1 (IFNGR1) LDTP02775 43.41  LDD1850 
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78 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Amyloid beta precursor like protein 2 (APLP2) LDTP05491 28.64  LDD1850 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 7.62  LDD1850 
Apolipoprotein L2 (APOL2) LDTP11076 14.72  LDD1850 
C-type mannose receptor 2 (MRC2) LDTP13114 26.17  LDD1850 
Calcium-binding and coiled-coil domain-containing protein 1 (CALCOCO1) LDTP13007 7.52  LDD1850 
Calcium-binding and coiled-coil domain-containing protein 2 (CALCOCO2) LDTP05764 20.82  LDD1850 
Calsyntenin-3 (CLSTN3) LDTP11096 28.64  LDD1850 
Calumenin (CALU) LDTP00887 14.93  LDD1850 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 10.56  LDD1850 
CD109 antigen (CD109) LDTP07760 15.24  LDD1850 
CD320 antigen (CD320) LDTP12352 25.63  LDD1850 
Collectin-12 (COLEC12) LDTP07031 41.36  LDD1850 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 20.25  LDD1850 
Desmocollin-3 (DSC3) LDTP06154 23.75  LDD1850 
Divergent protein kinase domain 2A (DIPK2A) LDTP09143 14.12  LDD1850 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 30.06  LDD1850 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 22.47  LDD1850 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 8.28  LDD1850 
Endothelial protein C receptor (PROCR) LDTP13669 16.00  LDD1850 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 21.11  LDD1850 
Ferritin light chain (FTL) LDTP01973 9.51  LDD1850 
FRAS1-related extracellular matrix protein 2 (FREM2) LDTP07080 10.70  LDD1850 
Galectin-3-binding protein (LGALS3BP) LDTP05558 36.25  LDD1850 
Ganglioside GM2 activator (GM2A) LDTP02927 35.51  LDD1850 
Golgi apparatus protein 1 (GLG1) LDTP09920 25.11  LDD1850 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 13.93  LDD1850 
Golgi membrane protein 1 (GOLM1) LDTP09054 16.56  LDD1850 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 8.75  LDD1850 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 7.46  LDD1850 
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) LDTP14272 12.47  LDD1850 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 54.95  LDD1850 
Lethal(3)malignant brain tumor-like protein 2 (L3MBTL2) LDTP10023 8.94  LDD1850 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 49.87  LDD1850 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 13.83  LDD1850 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 22.94  LDD1850 
Neuferricin (CYB5D2) LDTP15623 8.11  LDD1850 
Neurogenic locus notch homolog protein 2 (NOTCH2) LDTP05425 8.28  LDD1850 
Nicastrin (NCSTN) LDTP09787 17.27  LDD1850 
Nidogen-1 (NID1) LDTP02728 22.94  LDD1850 
Nuclear receptor coactivator 4 (NCOA4) LDTP05979 27.86  LDD1850 
Nucleobindin-2 (NUCB2) LDTP05160 13.74  LDD1850 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 7.41  LDD1850 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 7.31  LDD1850 
Nurim (NRM) LDTP08606 8.40  LDD1850 
Optic atrophy 3 protein (OPA3) LDTP16006 12.13  LDD1850 
Proteasome assembly chaperone 1 (PSMG1) LDTP01608 11.55  LDD1850 
Protein BANP (BANP) LDTP09007 10.13  LDD1850 
Protein CREG1 (CREG1) LDTP01279 54.95  LDD1850 
Protein CutA (CUTA) LDTP01075 12.55  LDD1850 
Protein FAM234B (FAM234B) LDTP18732 20.97  LDD1850 
Protein misato homolog 1 (MSTO1) LDTP11239 9.00  LDD1850 
Protein unc-119 homolog B (UNC119B) LDTP00105 10.63  LDD1850 
Protocadherin Fat 1 (FAT1) LDTP06134 11.71  LDD1850 
Protocadherin-7 (PCDH7) LDTP14468 8.34  LDD1850 
Reticulocalbin-2 (RCN2) LDTP06097 11.71  LDD1850 
RNA-binding protein FXR1 (FXR1) LDTP04395 8.00  LDD1850 
Scavenger receptor class A member 3 (SCARA3) LDTP07354 10.06  LDD1850 
Seizure 6-like protein 2 (SEZ6L2) LDTP07703 34.30  LDD1850 
Sequestosome-1 (SQSTM1) LDTP05898 48.84  LDD1850 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 19.43  LDD1850 
Synaptogyrin-2 (SYNGR2) LDTP00859 7.73  LDD1850 
Syntaxin-12 (STX12) LDTP08389 9.06  LDD1850 
Syntaxin-18 (STX18) LDTP13086 9.51  LDD1850 
Syntaxin-7 (STX7) LDTP00632 7.36  LDD1850 
Syntaxin-8 (STX8) LDTP13664 7.94  LDD1850 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 8.22  LDD1850 
Tax1-binding protein 1 (TAX1BP1) LDTP08294 27.67  LDD1850 
Teneurin-3 (TENM3) LDTP13025 7.57  LDD1850 
Testis-expressed protein 264 (TEX264) LDTP14259 10.63  LDD1850 
Tetraspanin-6 (TSPAN6) LDTP14458 21.11  LDD1850 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 7.62  LDD1850 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 20.11  LDD1850 
Trophoblast glycoprotein (TPBG) LDTP05960 9.71  LDD1850 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 18.00  LDD1850 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 9.71  LDD1850 
UPF0606 protein KIAA1549 (KIAA1549) LDTP12256 15.89  LDD1850 
Vacuolar protein-sorting-associated protein 25 (VPS25) LDTP11108 8.06  LDD1850 
Very low-density lipoprotein receptor (VLDLR) LDTP05215 33.59  LDD1850 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1850 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587