Details of the Target

General Information of Target

Target ID LDTP14993
Target Name Glycoprotein endo-alpha-1,2-mannosidase (MANEA)
Gene Name MANEA
Gene ID 79694
Synonyms
Glycoprotein endo-alpha-1,2-mannosidase; Endo-alpha mannosidase; Endomannosidase; hEndo; EC 3.2.1.130; Mandaselin
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MLPAVGSVDEEEDPAEEDCPELVPIETTQSEEEEKSGLGAKIPVTIITGYLGAGKTTLLN
YILTEQHSKRVAVILNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAI
ENLMQKKGKFDDILLETTGLADPGAVTSMFWVDAELGSDIYLDGIITIVDSKYGLKHLTE
EKPDGLINEATRQVALADIILINKTDLVPEEDVKKLRTTIRSINGLGQILETQRSRVDLS
NVLDLHAFDSLSGISLQKKLQHVPGTQPHLDQSIVTITFEVPGNAKEEHLNMFIQNLLWE
KNVRNKDNHCMEVIRLKGLVSIKDKSQQVIVQGVHELYDLEETPVSWKDDTERTNRLVLI
GRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT
Target Bioclass
Enzyme
Family
Glycosyl hydrolase 99 family
Subcellular location
Golgi apparatus membrane
Uniprot ID
Q5SRI9
Ensemble ID
ENST00000358812.9
HGNC ID
HGNC:21072

Probe(s) Labeling This Target

PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C170
 Probe Info  		8.22  LDD1850  [1]

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587