Details of the Target

General Information of Target

Target ID LDTP11725
Target Name AP-5 complex subunit mu-1 (AP5M1)
Gene Name AP5M1
Gene ID 55745
Synonyms
C14orf108; MUDENG; AP-5 complex subunit mu-1; Adaptor-related protein complex 5 subunit mu-1; Mu5; Mu-2-related death-inducing protein; MuD; Putative HIV-1 infection-related protein
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MELVLVFLCSLLAPMVLASAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRR
CKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN
Target Bioclass
Other
Family
Adaptor complexes medium subunit family
Subcellular location
Cytoplasm, cytosol
Function As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According toit may play a role in cell death.
Uniprot ID
Q9H0R1
Ensemble ID
ENST00000261558.8
HGNC ID
HGNC:20192

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HT SNV: p.Q3P .
IGROV1 SNV: p.G170R DBIA    Probe Info 
Ishikawa (Heraklio) 02 ER SNV: p.Y42C DBIA    Probe Info 
MFE296 SNV: p.T251I DBIA    Probe Info 
REH SNV: p.T184A .
SW1990 SNV: p.G131D DBIA    Probe Info 
YSCCC SNV: p.E352Q DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K466(10.00)  LDD0277  [1]
DBIA
 Probe Info  		C18(0.94)  LDD0531  [2]
m-APA
 Probe Info  		H368(0.00); H357(0.00); H344(0.00)  LDD2231  [3]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [4]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [4]
TPP-AC
 Probe Info  		N.A.  LDD0427  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C18(0.94)  LDD0531  [2]
 LDCM0215  AC10 HEK-293T C18(1.03)  LDD1508  [6]
 LDCM0216  AC100 HEK-293T C18(1.01)  LDD0814  [2]
 LDCM0217  AC101 HEK-293T C18(1.22)  LDD0815  [2]
 LDCM0218  AC102 HEK-293T C18(1.26)  LDD0816  [2]
 LDCM0219  AC103 HEK-293T C18(1.42)  LDD0817  [2]
 LDCM0220  AC104 HEK-293T C18(1.00)  LDD0818  [2]
 LDCM0221  AC105 HEK-293T C18(1.06)  LDD0819  [2]
 LDCM0222  AC106 HEK-293T C18(1.45)  LDD0820  [2]
 LDCM0223  AC107 HEK-293T C18(1.12)  LDD0821  [2]
 LDCM0224  AC108 HEK-293T C18(1.44)  LDD0822  [2]
 LDCM0225  AC109 HEK-293T C18(1.60)  LDD0823  [2]
 LDCM0226  AC11 HEK-293T C18(0.93)  LDD1509  [6]
 LDCM0227  AC110 HEK-293T C18(1.11)  LDD0825  [2]
 LDCM0228  AC111 HEK-293T C18(1.24)  LDD0826  [2]
 LDCM0229  AC112 HEK-293T C18(1.31)  LDD0827  [2]
 LDCM0230  AC113 HEK-293T C18(1.15)  LDD0828  [2]
 LDCM0231  AC114 HEK-293T C18(1.38)  LDD0829  [2]
 LDCM0232  AC115 HEK-293T C18(1.40)  LDD0830  [2]
 LDCM0233  AC116 HEK-293T C18(1.68)  LDD0831  [2]
 LDCM0234  AC117 HEK-293T C18(1.26)  LDD0832  [2]
 LDCM0235  AC118 HEK-293T C18(1.26)  LDD0833  [2]
 LDCM0236  AC119 HEK-293T C18(1.03)  LDD0834  [2]
 LDCM0237  AC12 HEK-293T C18(0.95)  LDD1510  [6]
 LDCM0238  AC120 HEK-293T C18(1.39)  LDD0836  [2]
 LDCM0239  AC121 HEK-293T C18(1.11)  LDD0837  [2]
 LDCM0240  AC122 HEK-293T C18(1.30)  LDD0838  [2]
 LDCM0241  AC123 HEK-293T C18(1.19)  LDD0839  [2]
 LDCM0242  AC124 HEK-293T C18(1.63)  LDD0840  [2]
 LDCM0243  AC125 HEK-293T C18(1.27)  LDD0841  [2]
 LDCM0244  AC126 HEK-293T C18(1.05)  LDD0842  [2]
 LDCM0245  AC127 HEK-293T C18(1.26)  LDD0843  [2]
 LDCM0259  AC14 HEK-293T C18(0.88)  LDD1512  [6]
 LDCM0263  AC143 HCT 116 C18(1.26)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C18(0.89)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C18(0.81)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C18(1.05)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C18(0.93)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C18(1.80)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C18(1.11)  LDD0586  [2]
 LDCM0270  AC15 HEK-293T C18(0.92)  LDD1513  [6]
 LDCM0271  AC150 HCT 116 C18(1.08)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C18(0.97)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C18(1.13)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C18(1.26)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C18(0.89)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C18(1.14)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C18(1.03)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C18(1.20)  LDD2161  [2]
 LDCM0276  AC17 HEK-293T C18(0.97)  LDD1515  [6]
 LDCM0277  AC18 HEK-293T C18(1.05)  LDD1516  [6]
 LDCM0278  AC19 HEK-293T C18(0.92)  LDD1517  [6]
 LDCM0279  AC2 HCT 116 C18(0.72)  LDD0596  [2]
 LDCM0280  AC20 HEK-293T C18(0.98)  LDD1519  [6]
 LDCM0281  AC21 HEK-293T C18(1.11)  LDD1520  [6]
 LDCM0282  AC22 HEK-293T C18(0.91)  LDD1521  [6]
 LDCM0283  AC23 HEK-293T C18(0.98)  LDD1522  [6]
 LDCM0284  AC24 HEK-293T C18(0.97)  LDD1523  [6]
 LDCM0285  AC25 HEK-293T C18(0.97)  LDD0883  [2]
 LDCM0286  AC26 HEK-293T C18(0.92)  LDD0884  [2]
 LDCM0287  AC27 HEK-293T C18(0.88)  LDD0885  [2]
 LDCM0288  AC28 HEK-293T C18(0.90)  LDD0886  [2]
 LDCM0289  AC29 HEK-293T C18(1.50)  LDD0887  [2]
 LDCM0290  AC3 HCT 116 C18(0.74)  LDD0607  [2]
 LDCM0291  AC30 HEK-293T C18(0.91)  LDD0889  [2]
 LDCM0292  AC31 HEK-293T C18(0.83)  LDD0890  [2]
 LDCM0293  AC32 HEK-293T C18(1.25)  LDD0891  [2]
 LDCM0294  AC33 HEK-293T C18(1.06)  LDD0892  [2]
 LDCM0295  AC34 HEK-293T C18(0.84)  LDD0893  [2]
 LDCM0296  AC35 HEK-293T C18(1.05)  LDD0894  [2]
 LDCM0297  AC36 HEK-293T C18(0.77)  LDD0895  [2]
 LDCM0298  AC37 HEK-293T C18(0.65)  LDD0896  [2]
 LDCM0299  AC38 HEK-293T C18(0.74)  LDD0897  [2]
 LDCM0300  AC39 HEK-293T C18(0.73)  LDD0898  [2]
 LDCM0301  AC4 HCT 116 C18(0.82)  LDD0618  [2]
 LDCM0302  AC40 HEK-293T C18(0.86)  LDD0900  [2]
 LDCM0303  AC41 HEK-293T C18(0.77)  LDD0901  [2]
 LDCM0304  AC42 HEK-293T C18(0.89)  LDD0902  [2]
 LDCM0305  AC43 HEK-293T C18(0.98)  LDD0903  [2]
 LDCM0306  AC44 HEK-293T C18(0.76)  LDD0904  [2]
 LDCM0307  AC45 HEK-293T C18(0.75)  LDD0905  [2]
 LDCM0308  AC46 HEK-293T C18(0.92)  LDD0906  [2]
 LDCM0309  AC47 HEK-293T C18(0.93)  LDD0907  [2]
 LDCM0310  AC48 HEK-293T C18(0.93)  LDD0908  [2]
 LDCM0311  AC49 HEK-293T C18(0.82)  LDD0909  [2]
 LDCM0312  AC5 HCT 116 C18(0.92)  LDD0629  [2]
 LDCM0313  AC50 HEK-293T C18(0.82)  LDD0911  [2]
 LDCM0314  AC51 HEK-293T C18(0.60)  LDD0912  [2]
 LDCM0315  AC52 HEK-293T C18(0.67)  LDD0913  [2]
 LDCM0316  AC53 HEK-293T C18(0.76)  LDD0914  [2]
 LDCM0317  AC54 HEK-293T C18(0.61)  LDD0915  [2]
 LDCM0318  AC55 HEK-293T C18(0.81)  LDD0916  [2]
 LDCM0319  AC56 HEK-293T C18(0.87)  LDD0917  [2]
 LDCM0320  AC57 HEK-293T C18(0.92)  LDD1559  [6]
 LDCM0321  AC58 HEK-293T C18(1.02)  LDD1560  [6]
 LDCM0322  AC59 HEK-293T C18(1.10)  LDD1561  [6]
 LDCM0323  AC6 HEK-293T C18(0.91)  LDD1562  [6]
 LDCM0324  AC60 HEK-293T C18(1.01)  LDD1563  [6]
 LDCM0325  AC61 HEK-293T C18(1.12)  LDD1564  [6]
 LDCM0326  AC62 HEK-293T C18(0.80)  LDD1565  [6]
 LDCM0327  AC63 HEK-293T C18(0.97)  LDD1566  [6]
 LDCM0328  AC64 HEK-293T C18(0.97)  LDD1567  [6]
 LDCM0332  AC68 HCT 116 C18(1.26)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C18(1.15)  LDD0650  [2]
 LDCM0334  AC7 HEK-293T C18(1.13)  LDD1568  [6]
 LDCM0335  AC70 HCT 116 C18(1.02)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C18(1.17)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C18(1.37)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C18(1.30)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C18(1.18)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C18(1.10)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C18(1.10)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C18(1.40)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C18(1.02)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C18(1.17)  LDD0661  [2]
 LDCM0345  AC8 HEK-293T C18(0.95)  LDD1569  [6]
 LDCM0346  AC80 HCT 116 C18(1.14)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C18(1.32)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C18(1.22)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C18(0.80)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C18(0.93)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C18(0.93)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C18(0.95)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C18(0.79)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C18(0.82)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C18(1.08)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C18(0.84)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C18(0.88)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C18(0.81)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C18(0.90)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C18(0.90)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C18(0.79)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C18(0.85)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C18(0.94)  LDD0681  [2]
 LDCM0365  AC98 HEK-293T C18(1.13)  LDD0963  [2]
 LDCM0366  AC99 HEK-293T C18(1.55)  LDD0964  [2]
 LDCM0248  AKOS034007472 HEK-293T C18(0.97)  LDD1511  [6]
 LDCM0356  AKOS034007680 HEK-293T C18(0.93)  LDD1570  [6]
 LDCM0275  AKOS034007705 HEK-293T C18(1.03)  LDD1514  [6]
 LDCM0367  CL1 HEK-293T C18(0.93)  LDD1571  [6]
 LDCM0368  CL10 HEK-293T C18(0.86)  LDD1572  [6]
 LDCM0369  CL100 HCT 116 C18(0.80)  LDD0686  [2]
 LDCM0370  CL101 HEK-293T C18(1.10)  LDD1574  [6]
 LDCM0371  CL102 HEK-293T C18(0.84)  LDD1575  [6]
 LDCM0372  CL103 HEK-293T C18(1.02)  LDD1576  [6]
 LDCM0373  CL104 HEK-293T C18(1.01)  LDD1577  [6]
 LDCM0374  CL105 HEK-293T C18(1.04)  LDD1578  [6]
 LDCM0375  CL106 HEK-293T C18(0.83)  LDD1579  [6]
 LDCM0376  CL107 HEK-293T C18(1.10)  LDD1580  [6]
 LDCM0377  CL108 HEK-293T C18(0.89)  LDD1581  [6]
 LDCM0378  CL109 HEK-293T C18(1.09)  LDD1582  [6]
 LDCM0379  CL11 HEK-293T C18(0.89)  LDD1583  [6]
 LDCM0380  CL110 HEK-293T C18(0.80)  LDD1584  [6]
 LDCM0381  CL111 HEK-293T C18(1.12)  LDD1585  [6]
 LDCM0382  CL112 HEK-293T C18(1.20)  LDD0980  [2]
 LDCM0383  CL113 HEK-293T C18(1.12)  LDD0981  [2]
 LDCM0384  CL114 HEK-293T C18(0.83)  LDD0982  [2]
 LDCM0385  CL115 HEK-293T C18(0.80)  LDD0983  [2]
 LDCM0386  CL116 HEK-293T C18(0.93)  LDD0984  [2]
 LDCM0387  CL117 HEK-293T C18(0.80)  LDD0985  [2]
 LDCM0388  CL118 HEK-293T C18(0.79)  LDD0986  [2]
 LDCM0389  CL119 HEK-293T C18(0.78)  LDD0987  [2]
 LDCM0390  CL12 HEK-293T C18(1.02)  LDD1594  [6]
 LDCM0391  CL120 HEK-293T C18(0.78)  LDD0989  [2]
 LDCM0392  CL121 HEK-293T C18(0.80)  LDD0990  [2]
 LDCM0393  CL122 HEK-293T C18(0.82)  LDD0991  [2]
 LDCM0394  CL123 HEK-293T C18(0.90)  LDD0992  [2]
 LDCM0395  CL124 HEK-293T C18(0.92)  LDD0993  [2]
 LDCM0396  CL125 HEK-293T C18(0.98)  LDD1600  [6]
 LDCM0397  CL126 HEK-293T C18(0.99)  LDD1601  [6]
 LDCM0398  CL127 HEK-293T C18(1.06)  LDD1602  [6]
 LDCM0399  CL128 HEK-293T C18(1.03)  LDD1603  [6]
 LDCM0400  CL13 HEK-293T C18(0.95)  LDD1604  [6]
 LDCM0401  CL14 HEK-293T C18(0.90)  LDD1605  [6]
 LDCM0402  CL15 HEK-293T C18(1.15)  LDD1606  [6]
 LDCM0403  CL16 HEK-293T C18(1.02)  LDD1607  [6]
 LDCM0404  CL17 HEK-293T C18(1.12)  LDD1608  [6]
 LDCM0405  CL18 HEK-293T C18(1.09)  LDD1609  [6]
 LDCM0406  CL19 HEK-293T C18(1.01)  LDD1610  [6]
 LDCM0407  CL2 HEK-293T C18(0.95)  LDD1611  [6]
 LDCM0408  CL20 HEK-293T C18(1.00)  LDD1612  [6]
 LDCM0409  CL21 HEK-293T C18(1.03)  LDD1613  [6]
 LDCM0410  CL22 HEK-293T C18(0.98)  LDD1614  [6]
 LDCM0411  CL23 HEK-293T C18(1.00)  LDD1615  [6]
 LDCM0412  CL24 HEK-293T C18(1.10)  LDD1616  [6]
 LDCM0413  CL25 HEK-293T C18(0.52)  LDD1617  [6]
 LDCM0414  CL26 HEK-293T C18(0.98)  LDD1618  [6]
 LDCM0415  CL27 HEK-293T C18(1.21)  LDD1619  [6]
 LDCM0416  CL28 HEK-293T C18(0.85)  LDD1620  [6]
 LDCM0417  CL29 HEK-293T C18(0.98)  LDD1621  [6]
 LDCM0418  CL3 HEK-293T C18(1.06)  LDD1622  [6]
 LDCM0419  CL30 HEK-293T C18(1.11)  LDD1623  [6]
 LDCM0420  CL31 HCT 116 C18(1.38)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C18(1.42)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C18(1.18)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C18(1.23)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C18(1.07)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C18(1.01)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C18(1.02)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C18(1.05)  LDD0745  [2]
 LDCM0429  CL4 HEK-293T C18(1.19)  LDD1633  [6]
 LDCM0430  CL40 HCT 116 C18(1.79)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C18(0.83)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C18(1.27)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C18(1.37)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C18(1.27)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C18(1.62)  LDD0752  [2]
 LDCM0436  CL46 HEK-293T C18(0.86)  LDD1034  [2]
 LDCM0437  CL47 HEK-293T C18(0.81)  LDD1035  [2]
 LDCM0438  CL48 HEK-293T C18(0.82)  LDD1036  [2]
 LDCM0439  CL49 HEK-293T C18(0.79)  LDD1037  [2]
 LDCM0440  CL5 HEK-293T C18(0.99)  LDD1644  [6]
 LDCM0441  CL50 HEK-293T C18(0.70)  LDD1039  [2]
 LDCM0442  CL51 HEK-293T C18(0.78)  LDD1040  [2]
 LDCM0443  CL52 HEK-293T C18(1.23)  LDD1041  [2]
 LDCM0444  CL53 HEK-293T C18(1.03)  LDD1042  [2]
 LDCM0445  CL54 HEK-293T C18(0.76)  LDD1043  [2]
 LDCM0446  CL55 HEK-293T C18(0.83)  LDD1044  [2]
 LDCM0447  CL56 HEK-293T C18(0.89)  LDD1045  [2]
 LDCM0448  CL57 HEK-293T C18(0.78)  LDD1046  [2]
 LDCM0449  CL58 HEK-293T C18(0.85)  LDD1047  [2]
 LDCM0450  CL59 HEK-293T C18(0.72)  LDD1048  [2]
 LDCM0451  CL6 HEK-293T C18(0.99)  LDD1654  [6]
 LDCM0452  CL60 HEK-293T C18(0.85)  LDD1050  [2]
 LDCM0453  CL61 HEK-293T C18(0.98)  LDD1656  [6]
 LDCM0454  CL62 HEK-293T C18(0.99)  LDD1657  [6]
 LDCM0455  CL63 HEK-293T C18(1.04)  LDD1658  [6]
 LDCM0456  CL64 HEK-293T C18(0.99)  LDD1659  [6]
 LDCM0457  CL65 HEK-293T C18(1.05)  LDD1660  [6]
 LDCM0458  CL66 HEK-293T C18(1.07)  LDD1661  [6]
 LDCM0459  CL67 HEK-293T C18(1.00)  LDD1662  [6]
 LDCM0460  CL68 HEK-293T C18(0.93)  LDD1663  [6]
 LDCM0461  CL69 HEK-293T C18(1.07)  LDD1664  [6]
 LDCM0462  CL7 HEK-293T C18(0.98)  LDD1665  [6]
 LDCM0463  CL70 HEK-293T C18(0.91)  LDD1666  [6]
 LDCM0464  CL71 HEK-293T C18(0.95)  LDD1667  [6]
 LDCM0465  CL72 HEK-293T C18(1.03)  LDD1668  [6]
 LDCM0466  CL73 HEK-293T C18(1.09)  LDD1669  [6]
 LDCM0467  CL74 HEK-293T C18(0.90)  LDD1670  [6]
 LDCM0469  CL76 HEK-293T C18(0.98)  LDD1672  [6]
 LDCM0470  CL77 HEK-293T C18(0.85)  LDD1673  [6]
 LDCM0471  CL78 HEK-293T C18(1.00)  LDD1674  [6]
 LDCM0472  CL79 HEK-293T C18(0.95)  LDD1675  [6]
 LDCM0473  CL8 HEK-293T C18(0.77)  LDD1676  [6]
 LDCM0474  CL80 HEK-293T C18(1.12)  LDD1677  [6]
 LDCM0475  CL81 HEK-293T C18(1.04)  LDD1678  [6]
 LDCM0476  CL82 HEK-293T C18(0.93)  LDD1679  [6]
 LDCM0477  CL83 HEK-293T C18(0.94)  LDD1680  [6]
 LDCM0478  CL84 HEK-293T C18(1.10)  LDD1681  [6]
 LDCM0479  CL85 HEK-293T C18(0.95)  LDD1682  [6]
 LDCM0480  CL86 HEK-293T C18(0.83)  LDD1683  [6]
 LDCM0481  CL87 HEK-293T C18(1.09)  LDD1684  [6]
 LDCM0482  CL88 HEK-293T C18(0.93)  LDD1685  [6]
 LDCM0483  CL89 HEK-293T C18(1.06)  LDD1686  [6]
 LDCM0484  CL9 HEK-293T C18(1.07)  LDD1687  [6]
 LDCM0485  CL90 HEK-293T C18(0.91)  LDD1688  [6]
 LDCM0486  CL91 HCT 116 C18(0.78)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C18(0.56)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C18(0.58)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C18(0.74)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C18(0.81)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C18(0.79)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C18(0.82)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C18(0.64)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C18(0.75)  LDD0811  [2]
 LDCM0495  E2913 HEK-293T C18(1.01)  LDD1698  [6]
 LDCM0468  Fragment33 HEK-293T C18(1.38)  LDD1671  [6]
 LDCM0427  Fragment51 HCT 116 C18(1.82)  LDD0744  [2]
 LDCM0022  KB02 HEK-293T C18(0.86)  LDD1492  [6]
 LDCM0023  KB03 HEK-293T C18(0.94)  LDD1497  [6]
 LDCM0024  KB05 HMCB C18(2.03)  LDD3312  [7]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
AP-5 complex subunit beta-1 (AP5B1) . Q2VPB7

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
4 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
5 Differently Tagged Probes for Protein Profiling of Mitochondria. Chembiochem. 2019 May 2;20(9):1155-1160. doi: 10.1002/cbic.201800735. Epub 2019 Mar 26.
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
7 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840