Details of the Target

General Information of Target

Target ID LDTP03575
Target Name Protein S100-A7 (S100A7)
Gene Name S100A7
Gene ID 6278
Synonyms
PSOR1; S100A7C; Protein S100-A7; Psoriasin; S100 calcium-binding protein A7
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSNTQAERSIIGMIDMFHKYTRRDDKIEKPSLLTMMKENFPNFLSACDKKGTNYLADVFE
KKDKNEDKKIDFSEFLSLLGDIATDYHKQSHGAAPCSGGSQ
Target Bioclass
Other
Family
S-100 family
Subcellular location
Cytoplasm
Uniprot ID
P31151
Ensemble ID
ENST00000368722.5
HGNC ID
HGNC:10497

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
P2
 Probe Info  		1.80  LDD0453  [1]
P8
 Probe Info  		3.26  LDD0455  [1]
MPP-AC
 Probe Info  		N.A.  LDD0428  [2]
TER-AC
 Probe Info  		N.A.  LDD0426  [2]
TPP-AC
 Probe Info  		N.A.  LDD0427  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ran-binding protein 9 (RANBP9) RANBP9/10 family Q96S59
Protein S100-A7-like 2 (S100A7L2) S-100 family Q5SY68
Clavesin-2 (CLVS2) . Q5SYC1

The Drug(s) Related To This Target

Approved
Click To Hide/Show 6 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Dexibuprofen Small molecular drug DB09213
Ibuprofen Small molecular drug DB01050
Zinc . DB01593
Zinc Acetate . DB14487
Zinc Chloride . DB14533
Zinc Sulfate Unspecified Form . DB14548
Investigative
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
8-anilinonaphthalene-1-sulfonic Acid Small molecular drug DB04474

References

1 Comparison of Different Competitive Proteome Profiling Approaches in Target Identification of Covalent Inhibitors. Chembiochem. 2022 Dec 16;23(24):e202200389. doi: 10.1002/cbic.202200389. Epub 2022 Nov 22.
2 Differently Tagged Probes for Protein Profiling of Mitochondria. Chembiochem. 2019 May 2;20(9):1155-1160. doi: 10.1002/cbic.201800735. Epub 2019 Mar 26.