General Information of Experiment

Probe Name MPP-AC  Probe Info 
Probe concentration 10 uM
Criteria Other data
In Vivo Experiment Model Model Type Living cell
Derived Tissue Cervix uteri
Disease Model Endocervical adenocarcinoma [ICD-11:2C77]
Model Name Human endocervical adenocarcinoma cells (HeLa)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 127 Protein Related to This Bioclass
Target ID Target Name
 LDTP17107  .
 LDTP06612  2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1)
 LDTP10954  3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10)
 LDTP03611  3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH)
 LDTP02522  60 kDa heat shock protein, mitochondrial (HSPD1)
 LDTP04636  Adenylate kinase 2, mitochondrial (AK2)
 LDTP04907  ADP-ribosylation factor 3 (ARF3)
 LDTP03900  ADP-ribosylation factor-like protein 1 (ARL1)
 LDTP13462  ADP-sugar pyrophosphatase (NUDT5)
 LDTP04253  Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1)
 LDTP10725  Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (ALKBH3)
 LDTP02072  Arginase-1 (ARG1)
 LDTP02888  Aspartate aminotransferase, cytoplasmic (GOT1)
 LDTP01783  Aspartate aminotransferase, mitochondrial (GOT2)
 LDTP02150  ATP synthase subunit beta, mitochondrial (ATP5F1B)
 LDTP02216  Beta-hexosaminidase subunit beta (HEXB)
 LDTP03159  Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS)
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5)
 LDTP05992  Bleomycin hydrolase (BLMH)
 LDTP12163  Calcyclin-binding protein (CACYBP)
 LDTP02204  Calpain-1 catalytic subunit (CAPN1)
 LDTP13329  Carboxypeptidase A4 (CPA4)
 LDTP03616  Caspase-14 (CASP14)
 LDTP02001  Catalase (CAT)
 LDTP02198  Cathepsin D (CTSD)
 LDTP13147  Cathepsin Z (CTSZ)
 LDTP04886  Cell division control protein 42 homolog (CDC42)
 LDTP01205  Citrate synthase, mitochondrial (CS)
 LDTP02149  Cyclin-dependent kinase 1 (CDK1)
 LDTP03610  Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1)
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2)
 LDTP02283  Cytochrome c1, heme protein, mitochondrial (CYC1)
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH)
 LDTP14805  D-beta-hydroxybutyrate dehydrogenase, mitochondrial (BDH1)
 LDTP02684  Delta-aminolevulinic acid dehydratase (ALAD)
 LDTP02362  Dihydrolipoyl dehydrogenase, mitochondrial (DLD)
 LDTP04572  Dipeptidyl peptidase 1 (CTSC)
 LDTP09239  DNA helicase B (HELB)
 LDTP01047  Dolichol-phosphate mannosyltransferase subunit 1 (DPM1)
 LDTP02694  Electron transfer flavoprotein subunit alpha, mitochondrial (ETFA)
 LDTP03849  Electron transfer flavoprotein subunit beta (ETFB)
 LDTP04251  Elongation factor Tu, mitochondrial (TUFM)
 LDTP02534  Endoplasmic reticulum chaperone BiP (HSPA5)
 LDTP03965  Enoyl-CoA delta isomerase 1, mitochondrial (ECI1)
 LDTP11738  Ester hydrolase C11orf54 (C11orf54)
 LDTP06089  Eukaryotic initiation factor 4A-II (EIF4A2)
 LDTP13602  Fizzy-related protein homolog (FZR1)
 LDTP02008  Fructose-bisphosphate aldolase A (ALDOA)
 LDTP02386  Fructose-bisphosphate aldolase C (ALDOC)
 LDTP01164  Gamma-glutamylcyclotransferase (GGCT)
 LDTP01334  Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial (GATB)
 LDTP03786  Glutaredoxin-1 (GLRX)
 LDTP02333  Glutathione S-transferase P (GSTP1)
 LDTP05007  GTP-binding nuclear protein Ran (RAN)
 LDTP15740  GTP-binding protein Di-Ras2 (DIRAS2)
 LDTP06728  Hexokinase HKDC1 (HKDC1)
 LDTP02602  Histidine--tRNA ligase, cytoplasmic (HARS1)
 LDTP06645  Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH)
 LDTP02743  Insulin-degrading enzyme (IDE)
 LDTP00713  Kallikrein-10 (KLK10)
 LDTP13948  Kallikrein-5 (KLK5)
 LDTP04322  Kallikrein-7 (KLK7)
 LDTP02179  L-lactate dehydrogenase B chain (LDHB)
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1)
 LDTP02505  Lysosomal protective protein (CTSA)
 LDTP03908  Malate dehydrogenase, mitochondrial (MDH2)
 LDTP10776  Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCC1)
 LDTP08596  Mitochondrial Rho GTPase 2 (RHOT2)
 LDTP02995  NADH dehydrogenase flavoprotein 2, mitochondrial (NDUFV2)
 LDTP01238  NADH dehydrogenase iron-sulfur protein 3, mitochondrial (NDUFS3)
 LDTP00218  NADH dehydrogenase iron-sulfur protein 8, mitochondrial (NDUFS8)
 LDTP01770  NADH-cytochrome b5 reductase 3 (CYB5R3)
 LDTP04164  NADP-dependent malic enzyme (ME1)
 LDTP10878  Parkinson disease protein 7 (PARK7)
 LDTP05028  Peptidyl-prolyl cis-trans isomerase A (PPIA)
 LDTP03216  Peptidyl-prolyl cis-trans isomerase B (PPIB)
 LDTP13989  Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2)
 LDTP05503  Peroxiredoxin-1 (PRDX1)
 LDTP05773  Peroxiredoxin-4 (PRDX4)
 LDTP03510  Peroxiredoxin-6 (PRDX6)
 LDTP02774  Phosphoglycerate mutase 2 (PGAM2)
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1)
 LDTP09495  Probable glutathione peroxidase 8 (GPX8)
 LDTP02095  Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA)
 LDTP12040  Prostaglandin E synthase 2 (PTGES2)
 LDTP03330  Proteasome subunit alpha type-1 (PSMA1)
 LDTP03331  Proteasome subunit alpha type-2 (PSMA2)
 LDTP03332  Proteasome subunit alpha type-3 (PSMA3)
 LDTP04884  Proteasome subunit alpha type-6 (PSMA6)
 LDTP00449  Proteasome subunit alpha type-7 (PSMA7)
 LDTP03060  Proteasome subunit beta type-1 (PSMB1)
 LDTP04285  Proteasome subunit beta type-2 (PSMB2)
 LDTP03419  Proteasome subunit beta type-5 (PSMB5)
 LDTP03418  Proteasome subunit beta type-6 (PSMB6)
 LDTP10862  Proteasome subunit beta type-7 (PSMB7)
 LDTP02188  Protein disulfide-isomerase (P4HB)
 LDTP00798  Protein-glutamine gamma-glutamyltransferase 5 (TGM5)
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS)
 LDTP03644  Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1)
 LDTP10159  Pyrroline-5-carboxylate reductase 2 (PYCR2)
 LDTP02576  Pyruvate carboxylase, mitochondrial (PC)
 LDTP02549  Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB)
 LDTP02733  Pyruvate kinase PKM (PKM)
 LDTP05037  Ras-related C3 botulinum toxin substrate 1 (RAC1)
 LDTP04895  Ras-related protein Rab-10 (RAB10)
 LDTP05006  Ras-related protein Rab-1A (RAB1A)
 LDTP11733  Ras-related protein Rab-1B (RAB1B)
 LDTP13512  Ras-related protein Rab-21 (RAB21)
 LDTP04892  Ras-related protein Rab-2A (RAB2A)
 LDTP03050  Ras-related protein Rab-5A (RAB5A)
 LDTP04399  Ras-related protein Rab-7a (RAB7A)
 LDTP02557  Ras-related protein Ral-A (RALA)
 LDTP04910  Ras-related protein Rap-1b (RAP1B)
 LDTP07838  Septin-14 (SEPTIN14)
 LDTP03223  Small ribosomal subunit protein uS3 (RPS3)
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB)
 LDTP04566  Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1)
 LDTP03515  Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3)
 LDTP03023  Thymidine phosphorylase (TYMP)
 LDTP03258  Thymidylate kinase (DTYMK)
 LDTP04851  Triosephosphate isomerase (TPI1)
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1)
 LDTP05074  Tubulin alpha-1B chain (TUBA1B)
 LDTP05075  Tubulin alpha-4A chain (TUBA4A)
 LDTP12810  Tubulin alpha-8 chain (TUBA8)
 LDTP07231  Ubiquitin thioesterase OTU1 (YOD1)
 LDTP02548  Uridine 5'-monophosphate synthase (UMPS)
Transporter and channel
Click to Show/Hide to Show 38 Protein Related to This Bioclass
Target ID Target Name
 LDTP04953  14-3-3 protein gamma (YWHAG)
 LDTP05043  14-3-3 protein zeta/delta (YWHAZ)
 LDTP02087  ADP/ATP translocase 2 (SLC25A5)
 LDTP02609  ADP/ATP translocase 3 (SLC25A6)
 LDTP02010  Annexin A1 (ANXA1)
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB)
 LDTP03327  ATP synthase subunit alpha, mitochondrial (ATP5F1A)
 LDTP14509  ATP synthase subunit d, mitochondrial (ATP5PD)
 LDTP03810  ATP synthase subunit gamma, mitochondrial (ATP5F1C)
 LDTP04150  ATP synthase subunit O, mitochondrial (ATP5PO)
 LDTP03405  Calnexin (CANX)
 LDTP18125  Claudin-23 (CLDN23)
 LDTP05510  Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP)
 LDTP10989  Copine-1 (CPNE1)
 LDTP01133  Copine-3 (CPNE3)
 LDTP05231  Cytochrome c (CYCS)
 LDTP05056  Eukaryotic translation initiation factor 5A-1 (EIF5A)
 LDTP03107  Filamin-A (FLNA)
 LDTP02929  Galectin-3 (LGALS3)
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59)
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2)
 LDTP01352  PRA1 family protein 3 (ARL6IP5)
 LDTP01180  Programmed cell death protein 6 (PDCD6)
 LDTP03717  Prohibitin 1 (PHB1)
 LDTP10313  Protein S100-A16 (S100A16)
 LDTP14408  Protein shisa-8 (SHISA8)
 LDTP12090  Sideroflexin-1 (SFXN1)
 LDTP05057  Small ribosomal subunit protein RACK1 (RACK1)
 LDTP11778  Sodium-dependent neutral amino acid transporter SLC6A17 (SLC6A17)
 LDTP05238  Solute carrier family 25 member 3 (SLC25A3)
 LDTP03380  Stomatin (STOM)
 LDTP00310  Syntenin-1 (SDCBP)
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10)
 LDTP03811  V-type proton ATPase subunit E 1 (ATP6V1E1)
 LDTP12966  Vesicle-associated membrane protein-associated protein A (VAPA)
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1)
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2)
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3)
Transcription factor
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name
 LDTP12355  DNA methyltransferase 1-associated protein 1 (DMAP1)
 LDTP02343  High mobility group protein B1 (HMGB1)
 LDTP08133  Transcription factor AP-2-delta (TFAP2D)
Other
Click to Show/Hide to Show 88 Protein Related to This Bioclass
Target ID Target Name
 LDTP03618  14-3-3 protein sigma (SFN)
 LDTP04844  Actin-related protein 2/3 complex subunit 4 (ARPC4)
 LDTP01814  Alpha-2-macroglobulin (A2M)
 LDTP02631  Alpha-actinin-1 (ACTN1)
 LDTP04647  Alpha-soluble NSF attachment protein (NAPA)
 LDTP12826  Bcl-2-associated transcription factor 1 (BCLAF1)
 LDTP15705  BTB/POZ domain-containing protein KCTD12 (KCTD12)
 LDTP17309  BTB/POZ domain-containing protein KCTD16 (KCTD16)
 LDTP02047  Calpain small subunit 1 (CAPNS1)
 LDTP05778  Chromobox protein homolog 3 (CBX3)
 LDTP04073  Chromobox protein homolog 5 (CBX5)
 LDTP07513  Coiled-coil and C2 domain-containing protein 1A (CC2D1A)
 LDTP06403  Corneodesmosin (CDSN)
 LDTP03177  Cornifin-B (SPRR1B)
 LDTP03106  Cysteine and glycine-rich protein 1 (CSRP1)
 LDTP06450  ELAV-like protein 1 (ELAVL1)
 LDTP03283  Elongation factor 1-beta (EEF1B2)
 LDTP03499  Elongation factor 1-delta (EEF1D)
 LDTP03509  Endoplasmic reticulum resident protein 29 (ERP29)
 LDTP10046  Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1)
 LDTP09884  Envoplakin (EVPL)
 LDTP17117  Galectin-related protein (LGALSL)
 LDTP12144  GrpE protein homolog 1, mitochondrial (GRPEL1)
 LDTP12141  Guanine nucleotide-binding protein subunit beta-4 (GNB4)
 LDTP02434  Heat shock 70 kDa protein 1A (HSPA1A)
 LDTP02435  Heat shock 70 kDa protein 1B (HSPA1B)
 LDTP05697  Heat shock protein 75 kDa, mitochondrial (TRAP1)
 LDTP04621  Heat shock-related 70 kDa protein 2 (HSPA2)
 LDTP05768  Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0)
 LDTP03614  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3)
 LDTP04952  Heterogeneous nuclear ribonucleoprotein K (HNRNPK)
 LDTP03182  Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)
 LDTP02227  Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC)
 LDTP02845  Histone H1.2 (H1-2)
 LDTP02060  Histone H2A type 1-B/E (H2AC4; H2AC8)
 LDTP15019  Histone H3-7 (H3-7)
 LDTP14696  Large ribosomal subunit protein bL19m (MRPL19)
 LDTP03354  Large ribosomal subunit protein eL13 (RPL13)
 LDTP04919  Large ribosomal subunit protein eL15 (RPL15)
 LDTP05360  Large ribosomal subunit protein eL20 (RPL18A)
 LDTP05186  Large ribosomal subunit protein eL24 (RPL24)
 LDTP04922  Large ribosomal subunit protein eL27 (RPL27)
 LDTP05023  Large ribosomal subunit protein eL31 (RPL31)
 LDTP05024  Large ribosomal subunit protein uL1 (RPL10A)
 LDTP02109  Large ribosomal subunit protein uL10 (RPLP0)
 LDTP03517  Large ribosomal subunit protein uL11 (RPL12)
 LDTP13971  Large ribosomal subunit protein uL11m (MRPL11)
 LDTP02961  Large ribosomal subunit protein uL22 (RPL17)
 LDTP05001  Large ribosomal subunit protein uL23 (RPL23A)
 LDTP05026  Large ribosomal subunit protein uL5 (RPL11)
 LDTP03658  Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9)
 LDTP03236  Loricrin (LORICRIN)
 LDTP00487  Myosin regulatory light chain 12B (MYL12B)
 LDTP12953  NADH dehydrogenase 1 alpha subcomplex assembly factor 4 (NDUFAF4)
 LDTP02164  Nucleophosmin (NPM1)
 LDTP03520  Phosphatidylethanolamine-binding protein 1 (PEBP1)
 LDTP02084  Plasminogen activator inhibitor 2 (SERPINB2)
 LDTP02413  Polyubiquitin-C (UBC)
 LDTP01932  Prelamin-A/C (LMNA)
 LDTP14869  Proline-rich protein 4 (PRR4)
 LDTP19403  Protein KPLCE (KPLCE)
 LDTP12638  Protein lin-7 homolog C (LIN7C)
 LDTP11685  Protein MIS12 homolog (MIS12)
 LDTP03620  Protein S100-A11 (S100A11)
 LDTP03575  Protein S100-A7 (S100A7)
 LDTP02152  Protein S100-A9 (S100A9)
 LDTP13782  RNA transcription, translation and transport factor protein (RTRAF)
 LDTP05179  SAP domain-containing ribonucleoprotein (SARNP)
 LDTP08528  Serpin A12 (SERPINA12)
 LDTP14501  Serpin B7 (SERPINB7)
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB)
 LDTP04913  Small ribosomal subunit protein eS1 (RPS3A)
 LDTP04997  Small ribosomal subunit protein eS4, X isoform (RPS4X)
 LDTP04971  Small ribosomal subunit protein uS12 (RPS23)
 LDTP14323  Small ribosomal subunit protein uS2B (RPSA2)
 LDTP04966  Small ribosomal subunit protein uS9 (RPS16)
 LDTP01567  Structural maintenance of chromosomes protein 2 (SMC2)
 LDTP05113  T-complex protein 1 subunit beta (CCT2)
 LDTP11702  Toll-interacting protein (TOLLIP)
 LDTP03846  Transgelin-2 (TAGLN2)
 LDTP02683  Translationally-controlled tumor protein (TPT1)
 LDTP05068  Tropomyosin alpha-4 chain (TPM4)
 LDTP02205  Tubulin beta chain (TUBB)
 LDTP00759  Tumor protein D54 (TPD52L2)
 LDTP02365  U2 small nuclear ribonucleoprotein A' (SNRPA1)
 LDTP08766  Vacuolar protein sorting-associated protein 52 homolog (VPS52)
 LDTP01206  Vesicle-trafficking protein SEC22b (SEC22B)
 LDTP02297  Vimentin (VIM)

References

1 Differently Tagged Probes for Protein Profiling of Mitochondria. Chembiochem. 2019 May 2;20(9):1155-1160. doi: 10.1002/cbic.201800735. Epub 2019 Mar 26.