Details of the Target
General Information of Target
| Target ID | LDTP06403 | |||||
|---|---|---|---|---|---|---|
| Target Name | Corneodesmosin (CDSN) |
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| Gene Name | CDSN | |||||
| Gene ID | 1041 | |||||
| Synonyms |
Corneodesmosin; S protein |
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| 3D Structure | ||||||
| Sequence |
MGSSRAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKG
DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG SGSSLQGASGSSQLGSSSSHSGNSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTND NSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYI PSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVG GSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQ SAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQ SPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPS AGAKPCGSSSAGKIPCRSIRDILAQVKPLGPQLADPEVFLPQGELLNSP |
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| Target Bioclass |
Other
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| Subcellular location |
Secreted
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| Function | Important for the epidermal barrier integrity. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C391(0.94) | LDD2265 | [1] | |
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IMP-1710 Probe Info |
 |
2.92 | LDD0040 | [2] | |
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MPP-AC Probe Info |
 |
N.A. | LDD0428 | [3] | |
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TER-AC Probe Info |
 |
N.A. | LDD0426 | [3] | |
Competitor(s) Related to This Target
References