Details of the Target
General Information of Target
| Target ID | LDTP08528 | |||||
|---|---|---|---|---|---|---|
| Target Name | Serpin A12 (SERPINA12) | |||||
| Gene Name | SERPINA12 | |||||
| Gene ID | 145264 | |||||
| Synonyms |
Serpin A12; OL-64; Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin |
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| 3D Structure | ||||||
| Sequence |
MNPTLGLAIFLAVLLTVKGLLKPSFSPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLL
KKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYII HELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDF ISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPM MFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLS RRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKM DERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNPIGK |
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| Target Bioclass |
Other
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| Family |
Serpin family
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| Subcellular location |
Secreted
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| Function | Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
MPP-AC Probe Info |
 |
N.A. | LDD0428 | [1] | |
|
TER-AC Probe Info |
 |
N.A. | LDD0426 | [1] | |