Details of the Target

General Information of Target

Target ID LDTP11674
Target Name Extracellular glycoprotein lacritin (LACRT)
Gene Name LACRT
Gene ID 90070
Synonyms
Extracellular glycoprotein lacritin
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCP
RARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEP
LNFCERSRVCRCARAAAGPWRGWGRGLSPAHRPPAAQASPPGLSGLVHPSAQRPRRLPAG
PGRPLPARLRGPRGVPAGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAFRGLFTRNR
CLDGAIQAFASGWPPVLLDQLNPQGDPEHSLLQVSSTGRALERRSLLSILPVLALPALL
Target Bioclass
Other
Subcellular location
Secreted
Function Modulates secretion by lacrimal acinar cells.
Uniprot ID
Q9GZZ8
Ensemble ID
ENST00000257867.5
HGNC ID
HGNC:16430

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
TPP-AC
 Probe Info  		N.A.  LDD0427  [1]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C218
 Probe Info  		99.73  LDD1892  [2]
C221
 Probe Info  		99.73  LDD1895  [2]

References

1 Differently Tagged Probes for Protein Profiling of Mitochondria. Chembiochem. 2019 May 2;20(9):1155-1160. doi: 10.1002/cbic.201800735. Epub 2019 Mar 26.
2 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587