Probe Name	STS-1					Probe Info
Probe concentration	10 uM
Criteria	Other data
In Vivo Experiment Model	Model Type			Cell lysate
	Derived Tissue			Liver
	Disease Model		Hepatoblastoma [ICD-11:DB91]
	Model Name		Human hepatoblastoma cell lysate (Hep-G2)

Target ID	Target Name
LDTP13011	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1)
LDTP06286	116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2)
LDTP06612	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1)
LDTP05782	26S proteasome non-ATPase regulatory subunit 2 (PSMD2)
LDTP00714	26S proteasome non-ATPase regulatory subunit 3 (PSMD3)
LDTP06532	26S proteasome non-ATPase regulatory subunit 5 (PSMD5)
LDTP04196	26S proteasome non-ATPase regulatory subunit 8 (PSMD8)
LDTP04987	26S proteasome regulatory subunit 10B (PSMC6)
LDTP10954	3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10)
LDTP03998	3-ketoacyl-CoA thiolase, mitochondrial (ACAA2)
LDTP03291	Acetyl-CoA acetyltransferase, mitochondrial (ACAT1)
LDTP10982	Aconitate hydratase, mitochondrial (ACO2)
LDTP04876	Actin, cytoplasmic 1 (ACTB)
LDTP06905	Acylglycerol kinase, mitochondrial (AGK)
LDTP03242	Adenosylhomocysteinase (AHCY)
LDTP04636	Adenylate kinase 2, mitochondrial (AK2)
LDTP11127	ADP-dependent glucokinase (ADPGK)
LDTP04262	Alanine--tRNA ligase, cytoplasmic (AARS1)
LDTP02074	Aldehyde dehydrogenase, mitochondrial (ALDH2)
LDTP05436	Aldo-keto reductase family 1 member C1 (AKR1C1)
LDTP02100	Alkaline phosphatase, placental type (ALPP)
LDTP01687	Apoptosis-inducing factor 1, mitochondrial (AIFM1)
LDTP04601	Arginine--tRNA ligase, cytoplasmic (RARS1)
LDTP01783	Aspartate aminotransferase, mitochondrial (GOT2)
LDTP03424	ATP-binding cassette sub-family D member 3 (ABCD3)
LDTP04561	ATP-citrate synthase (ACLY)
LDTP02925	ATP-dependent 6-phosphofructokinase, liver type (PFKL)
LDTP05314	ATP-dependent 6-phosphofructokinase, platelet type (PFKP)
LDTP06618	ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP)
LDTP02222	Bifunctional glutamate/proline--tRNA ligase (EPRS1)
LDTP06219	Chromodomain-helicase-DNA-binding protein 4 (CHD4)
LDTP01205	Citrate synthase, mitochondrial (CS)
LDTP08296	Cullin-associated NEDD8-dissociated protein 1 (CAND1)
LDTP02149	Cyclin-dependent kinase 1 (CDK1)
LDTP05507	Cyclin-dependent kinase 18 (CDK18)
LDTP03299	Cyclin-dependent kinase 2 (CDK2)
LDTP04263	Cysteine--tRNA ligase, cytoplasmic (CARS1)
LDTP04646	Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1)
LDTP03669	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT)
LDTP18087	Dephospho-CoA kinase domain-containing protein (DCAKD)
LDTP02362	Dihydrolipoyl dehydrogenase, mitochondrial (DLD)
LDTP02497	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT)
LDTP12803	Dipeptidyl peptidase 3 (DPP3)
LDTP03680	DNA replication licensing factor MCM4 (MCM4)
LDTP06150	DNA replication licensing factor MCM6 (MCM6)
LDTP03682	DNA replication licensing factor MCM7 (MCM7)
LDTP05136	DNA-dependent protein kinase catalytic subunit (PRKDC)
LDTP02694	Electron transfer flavoprotein subunit alpha, mitochondrial (ETFA)
LDTP03849	Electron transfer flavoprotein subunit beta (ETFB)
LDTP02672	Elongation factor 2 (EEF2)
LDTP04251	Elongation factor Tu, mitochondrial (TUFM)
LDTP02534	Endoplasmic reticulum chaperone BiP (HSPA5)
LDTP03518	Enoyl-CoA hydratase, mitochondrial (ECHS1)
LDTP04878	Eukaryotic initiation factor 4A-I (EIF4A1)
LDTP03861	Eukaryotic initiation factor 4A-III (EIF4A3)
LDTP04243	Fatty acid synthase (FASN)
LDTP02868	Fumarylacetoacetase (FAH)
LDTP02328	Gamma-enolase (ENO2)
LDTP05954	GDP-L-fucose synthase (GFUS)
LDTP02569	Glucose-6-phosphate 1-dehydrogenase (G6PD)
LDTP02162	Glucose-6-phosphate isomerase (GPI)
LDTP00874	Glutathione S-transferase LANCL1 (LANCL1)
LDTP05128	Glutathione S-transferase omega-1 (GSTO1)
LDTP02552	Glycogen phosphorylase, brain form (PYGB)
LDTP04333	GMP synthase [glutamine-hydrolyzing] (GMPS)
LDTP02541	Heat shock cognate 71 kDa protein (HSPA8)
LDTP02991	Hexokinase-1 (HK1)
LDTP05301	Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)
LDTP14854	Inorganic pyrophosphatase (PPA1)
LDTP03003	Interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2)
LDTP04345	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A)
LDTP03947	Isoleucine--tRNA ligase, cytoplasmic (IARS1)
LDTP12588	Isoleucine--tRNA ligase, mitochondrial (IARS2)
LDTP16025	Ketosamine-3-kinase (FN3KRP)
LDTP06615	Kynureninase (KYNU)
LDTP11509	L-lactate dehydrogenase A-like 6B (LDHAL6B)
LDTP13056	Leucine--tRNA ligase, cytoplasmic (LARS1)
LDTP03817	Lon protease homolog, mitochondrial (LONP1)
LDTP06294	Lysine--tRNA ligase (KARS1)
LDTP02565	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM)
LDTP12915	Methionine adenosyltransferase 2 subunit beta (MAT2B)
LDTP04730	Methionine--tRNA ligase, cytoplasmic (MARS1)
LDTP05632	Mitochondrial-processing peptidase subunit alpha (PMPCA)
LDTP03764	Myosin-9 (MYH9)
LDTP13940	Nitric oxide synthase-interacting protein (NOSIP)
LDTP02796	Nucleoside diphosphate kinase A (NME1)
LDTP03169	Nucleoside diphosphate kinase B (NME2)
LDTP12610	Obg-like ATPase 1 (OLA1)
LDTP13972	Oligoribonuclease, mitochondrial (REXO2)
LDTP02021	Ornithine aminotransferase, mitochondrial (OAT)
LDTP13671	Peptidyl-prolyl cis-trans isomerase E (PPIE)
LDTP05503	Peroxiredoxin-1 (PRDX1)
LDTP03626	Peroxiredoxin-2 (PRDX2)
LDTP06638	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2)
LDTP01787	Phosphoglycerate kinase 1 (PGK1)
LDTP00527	Phosphoribosylformylglycinamidine synthase (PFAS)
LDTP02273	Porphobilinogen deaminase (HMBS)
LDTP08883	Prolyl 3-hydroxylase OGFOD1 (OGFOD1)
LDTP02096	Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB)
LDTP06338	Prostaglandin E synthase 3 (PTGES3)
LDTP03330	Proteasome subunit alpha type-1 (PSMA1)
LDTP03332	Proteasome subunit alpha type-3 (PSMA3)
LDTP04884	Proteasome subunit alpha type-6 (PSMA6)
LDTP00449	Proteasome subunit alpha type-7 (PSMA7)
LDTP03060	Proteasome subunit beta type-1 (PSMB1)
LDTP04285	Proteasome subunit beta type-2 (PSMB2)
LDTP04284	Proteasome subunit beta type-3 (PSMB3)
LDTP10862	Proteasome subunit beta type-7 (PSMB7)
LDTP10997	Protein arginine N-methyltransferase 1 (PRMT1)
LDTP00418	Protein arginine N-methyltransferase 5 (PRMT5)
LDTP02188	Protein disulfide-isomerase (P4HB)
LDTP02677	Protein disulfide-isomerase A4 (PDIA4)
LDTP00616	Protein phosphatase 1G (PPM1G)
LDTP02638	Proto-oncogene tyrosine-protein kinase Src (SRC)
LDTP10709	Pseudouridylate synthase 7 homolog (PUS7)
LDTP01781	Purine nucleoside phosphorylase (PNP)
LDTP04712	Puromycin-sensitive aminopeptidase (NPEPPS)
LDTP00343	Pyridoxal kinase (PDXK)
LDTP03552	Pyruvate kinase PKLR (PKLR)
LDTP02733	Pyruvate kinase PKM (PKM)
LDTP04895	Ras-related protein Rab-10 (RAB10)
LDTP05006	Ras-related protein Rab-1A (RAB1A)
LDTP13512	Ras-related protein Rab-21 (RAB21)
LDTP04910	Ras-related protein Rap-1b (RAP1B)
LDTP03592	Ribonucleoside-diphosphate reductase subunit M2 (RRM2)
LDTP04882	Ribose-phosphate pyrophosphokinase 1 (PRPS1)
LDTP04471	Ribosomal protein S6 kinase alpha-3 (RPS6KA3)
LDTP13787	RuvB-like 2 (RUVBL2)
LDTP03577	S-adenosylmethionine synthase isoform type-2 (MAT2A)
LDTP05052	S-phase kinase-associated protein 1 (SKP1)
LDTP06279	Septin-2 (SEPTIN2)
LDTP03689	Serine hydroxymethyltransferase, mitochondrial (SHMT2)
LDTP00299	Serine/threonine-protein kinase 25 (STK25)
LDTP06536	Serine/threonine-protein kinase N2 (PKN2)
LDTP05232	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PPP2R2B)
LDTP05064	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA)
LDTP03819	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC)
LDTP03223	Small ribosomal subunit protein uS3 (RPS3)
LDTP02067	Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1)
LDTP13107	SUMO-activating enzyme subunit 1 (SAE1)
LDTP02022	Thymidine kinase, cytosolic (TK1)
LDTP04665	Transitional endoplasmic reticulum ATPase (VCP)
LDTP06427	Translin (TSN)
LDTP03156	Trifunctional purine biosynthetic protein adenosine-3 (GART)
LDTP07907	Tubulin alpha-1A chain (TUBA1A)
LDTP05075	Tubulin alpha-4A chain (TUBA4A)
LDTP04617	Tyrosine--tRNA ligase, cytoplasmic (YARS1)
LDTP05478	Tyrosine-protein kinase BTK (BTK)
LDTP03944	Tyrosine-protein kinase CSK (CSK)
LDTP02231	Tyrosine-protein kinase Yes (YES1)
LDTP05070	Ubiquitin-conjugating enzyme E2 L3 (UBE2L3)
LDTP12851	UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1)
LDTP06517	UDP-N-acetylhexosamine pyrophosphorylase (UAP1)
LDTP11571	Uridine-cytidine kinase 2 (UCK2)
LDTP03859	V-type proton ATPase catalytic subunit A (ATP6V1A)
LDTP03366	Valine--tRNA ligase (VARS1)
LDTP12954	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3)
LDTP06901	Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12)

Target ID	Target Name
LDTP04969	14-3-3 protein epsilon (YWHAE)
LDTP03385	14-3-3 protein theta (YWHAQ)
LDTP05043	14-3-3 protein zeta/delta (YWHAZ)
LDTP02087	ADP/ATP translocase 2 (SLC25A5)
LDTP03768	Alpha-actinin-2 (ACTN2)
LDTP04150	ATP synthase subunit O, mitochondrial (ATP5PO)
LDTP03405	Calnexin (CANX)
LDTP00244	Chloride intracellular channel protein 1 (CLIC1)
LDTP12882	Chloride intracellular channel protein 5 (CLIC5)
LDTP05252	Clathrin heavy chain 1 (CLTC)
LDTP04578	Clathrin heavy chain 2 (CLTCL1)
LDTP05510	Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP)
LDTP13393	Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13)
LDTP04662	Exportin-2 (CSE1L)
LDTP06103	Filamin-C (FLNC)
LDTP11877	Golgi resident protein GCP60 (ACBD3)
LDTP05020	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2)
LDTP14066	Hypoxia up-regulated protein 1 (HYOU1)
LDTP04501	Importin subunit alpha-1 (KPNA2)
LDTP01574	Importin-7 (IPO7)
LDTP05303	Interferon-induced transmembrane protein 2 (IFITM2)
LDTP05305	Large neutral amino acids transporter small subunit 1 (SLC7A5)
LDTP00562	Membrane-associated progesterone receptor component 2 (PGRMC2)
LDTP14235	Mitochondrial carrier homolog 2 (MTCH2)
LDTP00635	Monocarboxylate transporter 4 (SLC16A3)
LDTP02612	Nucleoprotein TPR (TPR)
LDTP12090	Sideroflexin-1 (SFXN1)
LDTP04624	Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3)
LDTP00592	Surfeit locus protein 4 (SURF4)
LDTP01969	Transferrin receptor protein 1 (TFRC)
LDTP10741	Vacuolar protein sorting-associated protein 35 (VPS35)
LDTP01556	Vesicle-associated membrane protein-associated protein B/C (VAPB)
LDTP04071	Voltage-dependent anion-selective channel protein 2 (VDAC2)

Target ID	Target Name
LDTP05577	FACT complex subunit SSRP1 (SSRP1)
LDTP05065	Y-box-binding protein 1 (YBX1)

Target ID	Target Name
LDTP03617	14-3-3 protein beta/alpha (YWHAB)
LDTP00223	26S proteasome non-ATPase regulatory subunit 11 (PSMD11)
LDTP06273	26S proteasome non-ATPase regulatory subunit 6 (PSMD6)
LDTP09843	Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B)
LDTP04903	Actin-related protein 2 (ACTR2)
LDTP00551	Actin-related protein 2/3 complex subunit 2 (ARPC2)
LDTP16166	Actin-related protein 3B (ACTR3B)
LDTP05294	Adenylyl cyclase-associated protein 1 (CAP1)
LDTP02631	Alpha-actinin-1 (ACTN1)
LDTP00843	Alpha-actinin-4 (ACTN4)
LDTP01683	BAG family molecular chaperone regulator 2 (BAG2)
LDTP13955	Calcium-binding protein 39 (CAB39)
LDTP08760	Cell cycle and apoptosis regulator protein 2 (CCAR2)
LDTP06584	Cleavage and polyadenylation specificity factor subunit 6 (CPSF6)
LDTP14486	Clustered mitochondria protein homolog (CLUH)
LDTP03244	Cofilin-1 (CFL1)
LDTP12106	COP9 signalosome complex subunit 7b (COPS7B)
LDTP03283	Elongation factor 1-beta (EEF1B2)
LDTP03499	Elongation factor 1-delta (EEF1D)
LDTP03367	Elongation factor 1-gamma (EEF1G)
LDTP11021	Endophilin-A3 (SH3GL3)
LDTP02734	Endoplasmin (HSP90B1)
LDTP00619	Eukaryotic translation initiation factor 3 subunit D (EIF3D)
LDTP04544	F-actin-capping protein subunit alpha-1 (CAPZA1)
LDTP04127	F-actin-capping protein subunit beta (CAPZB)
LDTP02710	Glial fibrillary acidic protein (GFAP)
LDTP11911	Golgi phosphoprotein 3 (GOLPH3)
LDTP03695	Heat shock 70 kDa protein 4 (HSPA4)
LDTP05697	Heat shock protein 75 kDa, mitochondrial (TRAP1)
LDTP02053	Heat shock protein beta-1 (HSPB1)
LDTP04621	Heat shock-related 70 kDa protein 2 (HSPA2)
LDTP02364	Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1)
LDTP06032	Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD)
LDTP04514	Heterogeneous nuclear ribonucleoprotein F (HNRNPF)
LDTP03615	Heterogeneous nuclear ribonucleoprotein H (HNRNPH1)
LDTP04952	Heterogeneous nuclear ribonucleoprotein K (HNRNPK)
LDTP02750	Heterogeneous nuclear ribonucleoprotein L (HNRNPL)
LDTP04500	Heterogeneous nuclear ribonucleoprotein M (HNRNPM)
LDTP00991	Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP)
LDTP00756	Heterogeneous nuclear ribonucleoprotein R (HNRNPR)
LDTP12904	Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)
LDTP02674	Keratin, type I cytoskeletal 10 (KRT10)
LDTP03755	Keratin, type I cytoskeletal 9 (KRT9)
LDTP03792	Keratin, type II cytoskeletal 2 epidermal (KRT2)
LDTP05525	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1)
LDTP04537	Large ribosomal subunit protein bL12m (MRPL12)
LDTP02109	Large ribosomal subunit protein uL10 (RPLP0)
LDTP04106	Large ribosomal subunit protein uL18 (RPL5)
LDTP03815	Large ribosomal subunit protein uL4 (RPL4)
LDTP02116	Lupus La protein (SSB)
LDTP00648	Melanoma-associated antigen B2 (MAGEB2)
LDTP11079	Myb-binding protein 1A (MYBBP1A)
LDTP03503	Myristoylated alanine-rich C-kinase substrate (MARCKS)
LDTP04241	Nuclear autoantigenic sperm protein (NASP)
LDTP04684	Nucleosome assembly protein 1-like 1 (NAP1L1)
LDTP00306	Pescadillo homolog (PES1)
LDTP02691	Plastin-2 (LCP1)
LDTP06366	Poly(rC)-binding protein 1 (PCBP1)
LDTP06367	Poly(rC)-binding protein 2 (PCBP2)
LDTP02595	Polyadenylate-binding protein 1 (PABPC1)
LDTP03364	Polypyrimidine tract-binding protein 1 (PTBP1)
LDTP07526	Pre-mRNA-processing-splicing factor 8 (PRPF8)
LDTP02596	Proliferating cell nuclear antigen (PCNA)
LDTP05484	Proteasome activator complex subunit 1 (PSME1)
LDTP04917	Proteasome activator complex subunit 3 (PSME3)
LDTP06250	Proteasome activator complex subunit 4 (PSME4)
LDTP01608	Proteasome assembly chaperone 1 (PSMG1)
LDTP10035	Proteasome assembly chaperone 2 (PSMG2)
LDTP04355	Rab GDP dissociation inhibitor beta (GDI2)
LDTP04117	Ras GTPase-activating-like protein IQGAP1 (IQGAP1)
LDTP02964	Regulator of chromosome condensation (RCC1)
LDTP04510	Rho GDP-dissociation inhibitor 1 (ARHGDIA)
LDTP01379	Ribosomal L1 domain-containing protein 1 (RSL1D1)
LDTP13782	RNA transcription, translation and transport factor protein (RTRAF)
LDTP04363	Serpin H1 (SERPINH1)
LDTP00862	Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA)
LDTP04111	Small ribosomal subunit protein eS10 (RPS10)
LDTP04958	Small ribosomal subunit protein eS7 (RPS7)
LDTP09821	Stalled ribosome sensor GCN1 (GCN1)
LDTP03860	Stress-70 protein, mitochondrial (HSPA9)
LDTP03619	Stress-induced-phosphoprotein 1 (STIP1)
LDTP01567	Structural maintenance of chromosomes protein 2 (SMC2)
LDTP06557	Synaptophysin-like protein 1 (SYPL1)
LDTP04201	T-complex protein 1 subunit epsilon (CCT5)
LDTP10990	T-complex protein 1 subunit eta (CCT7)
LDTP03888	T-complex protein 1 subunit zeta (CCT6A)
LDTP02205	Tubulin beta chain (TUBB)
LDTP05998	Tubulin beta-2A chain (TUBB2A)
LDTP05904	Tubulin beta-3 chain (TUBB3)
LDTP02037	Tubulin beta-4A chain (TUBB4A)
LDTP05076	Tubulin beta-4B chain (TUBB4B)
LDTP05033	Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A)
LDTP01206	Vesicle-trafficking protein SEC22b (SEC22B)
LDTP08094	Wings apart-like protein homolog (WAPL)

1	Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe. Chem Commun (Camb). 2011 Oct 28;47(40):11306-8. doi: 10.1039/c1cc14824a. Epub 2011 Sep 16.