Details of the Target

General Information of Target

Target ID LDTP02353
Target Name Clathrin light chain B (CLTB)
Gene Name CLTB
Gene ID 1212
Synonyms
Clathrin light chain B; Lcb
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT
SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA
SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFV
KESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
Target Bioclass
Transporter and channel
Family
Clathrin light chain family
Subcellular location
Cytoplasmic vesicle membrane
Function Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Uniprot ID
P09497
Ensemble ID
ENST00000310418.9
HGNC ID
HGNC:2091

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
COLO678 SNV: p.Y87Ter DBIA    Probe Info 
OVK18 SNV: p.A132V DBIA    Probe Info 
SKMEL28 SNV: p.E39D DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 21 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
ONAyne
 Probe Info  		K207(0.13)  LDD0274  [2]
STPyne
 Probe Info  		K204(7.34); K207(10.00); K210(10.00); K223(5.17)  LDD0277  [2]
AZ-9
 Probe Info  		E127(1.07)  LDD2208  [3]
OPA-S-S-alkyne
 Probe Info  		K122(2.57)  LDD3494  [4]
BTD
 Probe Info  		C199(1.19)  LDD1700  [5]
DBIA
 Probe Info  		C199(1.95)  LDD0080  [6]
ATP probe
 Probe Info  		K204(0.00); K207(0.00)  LDD0199  [7]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [8]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [8]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [8]
IPM
 Probe Info  		N.A.  LDD0025  [9]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [9]
TFBX
 Probe Info  		N.A.  LDD0027  [9]
Phosphinate-6
 Probe Info  		C209(0.00); C199(0.00)  LDD0018  [10]
1c-yne
 Probe Info  		N.A.  LDD0228  [11]
Acrolein
 Probe Info  		N.A.  LDD0217  [12]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [12]
Methacrolein
 Probe Info  		N.A.  LDD0218  [12]
AOyne
 Probe Info  		15.00  LDD0443  [13]
NAIA_5
 Probe Info  		C199(0.00); C209(0.00)  LDD2223  [14]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STS-2
 Probe Info  		N.A.  LDD0139  [15]
VE-P
 Probe Info  		N.A.  LDD0396  [16]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C199(0.68)  LDD2142  [5]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C199(0.32)  LDD2112  [5]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C199(0.96)  LDD2117  [5]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C199(1.10)  LDD2152  [5]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C199(1.15)  LDD2103  [5]
 LDCM0214  AC1 HEK-293T C199(0.96)  LDD1507  [17]
 LDCM0215  AC10 HEK-293T C199(0.92)  LDD1508  [17]
 LDCM0216  AC100 HCT 116 C199(0.95)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C199(1.00)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C199(1.19)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C199(1.58)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C199(1.38)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C199(1.41)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C199(1.31)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C199(1.17)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C199(0.79)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C199(0.88)  LDD0542  [6]
 LDCM0226  AC11 HEK-293T C199(0.98)  LDD1509  [17]
 LDCM0227  AC110 HCT 116 C199(0.95)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C199(0.98)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C199(1.22)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C199(1.12)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C199(1.18)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C199(1.32)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C199(1.18)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C199(1.02)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C199(0.98)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C199(1.04)  LDD0553  [6]
 LDCM0237  AC12 HEK-293T C199(1.05)  LDD1510  [17]
 LDCM0238  AC120 HCT 116 C199(1.04)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C199(0.97)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C199(1.10)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C199(1.13)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C199(0.96)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C199(1.03)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C199(1.34)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C199(1.19)  LDD0562  [6]
 LDCM0259  AC14 HEK-293T C199(1.06)  LDD1512  [17]
 LDCM0263  AC143 HCT 116 C199(1.06)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C199(1.21)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C199(0.75)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C199(0.83)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C199(1.16)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C199(2.10)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C199(1.11)  LDD0586  [6]
 LDCM0270  AC15 HEK-293T C199(1.13)  LDD1513  [17]
 LDCM0271  AC150 HCT 116 C199(0.93)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C199(0.79)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C199(1.34)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C199(2.06)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C199(1.24)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C199(1.55)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C199(0.98)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C199(1.22)  LDD2161  [6]
 LDCM0276  AC17 HEK-293T C199(1.47)  LDD1515  [17]
 LDCM0277  AC18 HEK-293T C199(1.17)  LDD1516  [17]
 LDCM0278  AC19 HEK-293T C199(2.03)  LDD1517  [17]
 LDCM0279  AC2 HEK-293T C199(0.96)  LDD1518  [17]
 LDCM0280  AC20 HEK-293T C199(1.37)  LDD1519  [17]
 LDCM0281  AC21 HEK-293T C199(1.19)  LDD1520  [17]
 LDCM0282  AC22 HEK-293T C199(1.36)  LDD1521  [17]
 LDCM0283  AC23 HEK-293T C199(1.39)  LDD1522  [17]
 LDCM0284  AC24 HEK-293T C199(1.27)  LDD1523  [17]
 LDCM0285  AC25 HEK-293T C199(1.13)  LDD1524  [17]
 LDCM0286  AC26 HEK-293T C199(0.83)  LDD1525  [17]
 LDCM0287  AC27 HEK-293T C199(0.92)  LDD1526  [17]
 LDCM0288  AC28 HEK-293T C199(1.00)  LDD1527  [17]
 LDCM0289  AC29 HEK-293T C199(0.86)  LDD1528  [17]
 LDCM0290  AC3 HEK-293T C199(0.78)  LDD1529  [17]
 LDCM0291  AC30 HEK-293T C199(0.95)  LDD1530  [17]
 LDCM0292  AC31 HEK-293T C199(0.97)  LDD1531  [17]
 LDCM0293  AC32 HEK-293T C199(1.12)  LDD1532  [17]
 LDCM0294  AC33 HEK-293T C199(2.03)  LDD1533  [17]
 LDCM0295  AC34 HEK-293T C199(1.27)  LDD1534  [17]
 LDCM0296  AC35 HEK-293T C199(1.40)  LDD1535  [17]
 LDCM0297  AC36 HEK-293T C199(1.53)  LDD1536  [17]
 LDCM0298  AC37 HEK-293T C199(0.94)  LDD1537  [17]
 LDCM0299  AC38 HEK-293T C199(1.26)  LDD1538  [17]
 LDCM0300  AC39 HEK-293T C199(1.39)  LDD1539  [17]
 LDCM0301  AC4 HEK-293T C199(0.75)  LDD1540  [17]
 LDCM0302  AC40 HEK-293T C199(1.16)  LDD1541  [17]
 LDCM0303  AC41 HEK-293T C199(1.82)  LDD1542  [17]
 LDCM0304  AC42 HEK-293T C199(0.97)  LDD1543  [17]
 LDCM0305  AC43 HEK-293T C199(1.40)  LDD1544  [17]
 LDCM0306  AC44 HEK-293T C199(1.26)  LDD1545  [17]
 LDCM0307  AC45 HEK-293T C199(1.02)  LDD1546  [17]
 LDCM0308  AC46 HEK-293T C199(1.20)  LDD1547  [17]
 LDCM0309  AC47 HEK-293T C199(1.21)  LDD1548  [17]
 LDCM0310  AC48 HEK-293T C199(1.40)  LDD1549  [17]
 LDCM0311  AC49 HEK-293T C199(1.31)  LDD1550  [17]
 LDCM0312  AC5 HEK-293T C199(0.89)  LDD1551  [17]
 LDCM0313  AC50 HEK-293T C199(0.92)  LDD1552  [17]
 LDCM0314  AC51 HEK-293T C199(1.11)  LDD1553  [17]
 LDCM0315  AC52 HEK-293T C199(1.36)  LDD1554  [17]
 LDCM0316  AC53 HEK-293T C199(1.27)  LDD1555  [17]
 LDCM0317  AC54 HEK-293T C199(1.30)  LDD1556  [17]
 LDCM0318  AC55 HEK-293T C199(1.35)  LDD1557  [17]
 LDCM0319  AC56 HEK-293T C199(1.25)  LDD1558  [17]
 LDCM0320  AC57 HEK-293T C199(1.28)  LDD1559  [17]
 LDCM0321  AC58 HEK-293T C199(1.08)  LDD1560  [17]
 LDCM0322  AC59 HEK-293T C199(1.18)  LDD1561  [17]
 LDCM0323  AC6 HEK-293T C199(0.84)  LDD1562  [17]
 LDCM0324  AC60 HEK-293T C199(1.16)  LDD1563  [17]
 LDCM0325  AC61 HEK-293T C199(1.00)  LDD1564  [17]
 LDCM0326  AC62 HEK-293T C199(1.31)  LDD1565  [17]
 LDCM0327  AC63 HEK-293T C199(1.24)  LDD1566  [17]
 LDCM0328  AC64 HEK-293T C199(1.03)  LDD1567  [17]
 LDCM0332  AC68 HCT 116 C199(0.92)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C199(1.22)  LDD0650  [6]
 LDCM0334  AC7 HEK-293T C199(0.89)  LDD1568  [17]
 LDCM0335  AC70 HCT 116 C199(1.05)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C199(1.04)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C199(1.09)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C199(1.95)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C199(1.94)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C199(2.05)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C199(1.18)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C199(1.51)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C199(0.95)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C199(1.01)  LDD0661  [6]
 LDCM0345  AC8 HEK-293T C199(0.84)  LDD1569  [17]
 LDCM0346  AC80 HCT 116 C199(1.32)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C199(0.94)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C199(2.11)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C199(2.11)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C199(1.77)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C199(1.20)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C199(1.61)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C199(1.17)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C199(1.25)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C199(2.14)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C199(0.72)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C199(2.16)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C199(2.29)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C199(1.71)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C199(1.49)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C199(1.20)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C199(1.48)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C199(1.50)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C199(2.58)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C199(0.77)  LDD0683  [6]
 LDCM0520  AKOS000195272 MDA-MB-231 C199(0.88)  LDD2113  [5]
 LDCM0248  AKOS034007472 HEK-293T C199(1.19)  LDD1511  [17]
 LDCM0356  AKOS034007680 HEK-293T C199(1.14)  LDD1570  [17]
 LDCM0275  AKOS034007705 HEK-293T C199(1.05)  LDD1514  [17]
 LDCM0156  Aniline NCI-H1299 12.74  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C199(0.98)  LDD2171  [6]
 LDCM0498  BS-3668 MDA-MB-231 C199(0.79)  LDD2091  [5]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [12]
 LDCM0632  CL-Sc Hep-G2 C199(3.18)  LDD2227  [14]
 LDCM0367  CL1 HCT 116 C199(0.67)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C199(0.81)  LDD0685  [6]
 LDCM0369  CL100 HEK-293T C199(0.98)  LDD1573  [17]
 LDCM0370  CL101 HEK-293T C199(0.99)  LDD1574  [17]
 LDCM0371  CL102 HEK-293T C199(0.72)  LDD1575  [17]
 LDCM0372  CL103 HEK-293T C199(1.43)  LDD1576  [17]
 LDCM0373  CL104 HEK-293T C199(0.84)  LDD1577  [17]
 LDCM0374  CL105 HEK-293T C199(1.29)  LDD1578  [17]
 LDCM0375  CL106 HEK-293T C199(1.10)  LDD1579  [17]
 LDCM0376  CL107 HEK-293T C199(1.40)  LDD1580  [17]
 LDCM0377  CL108 HEK-293T C199(1.22)  LDD1581  [17]
 LDCM0378  CL109 HEK-293T C199(0.89)  LDD1582  [17]
 LDCM0379  CL11 HCT 116 C199(0.69)  LDD0696  [6]
 LDCM0380  CL110 HEK-293T C199(0.83)  LDD1584  [17]
 LDCM0381  CL111 HEK-293T C199(0.92)  LDD1585  [17]
 LDCM0382  CL112 HEK-293T C199(0.89)  LDD1586  [17]
 LDCM0383  CL113 HEK-293T C199(1.37)  LDD1587  [17]
 LDCM0384  CL114 HEK-293T C199(0.86)  LDD1588  [17]
 LDCM0385  CL115 HEK-293T C199(0.93)  LDD1589  [17]
 LDCM0386  CL116 HEK-293T C199(1.29)  LDD1590  [17]
 LDCM0387  CL117 HEK-293T C199(1.38)  LDD1591  [17]
 LDCM0388  CL118 HEK-293T C199(1.02)  LDD1592  [17]
 LDCM0389  CL119 HEK-293T C199(0.95)  LDD1593  [17]
 LDCM0390  CL12 HCT 116 C199(1.08)  LDD0707  [6]
 LDCM0391  CL120 HEK-293T C199(1.16)  LDD1595  [17]
 LDCM0392  CL121 HEK-293T C199(1.37)  LDD1596  [17]
 LDCM0393  CL122 HEK-293T C199(1.13)  LDD1597  [17]
 LDCM0394  CL123 HEK-293T C199(1.02)  LDD1598  [17]
 LDCM0395  CL124 HEK-293T C199(0.97)  LDD1599  [17]
 LDCM0396  CL125 HEK-293T C199(0.98)  LDD1600  [17]
 LDCM0397  CL126 HEK-293T C199(1.07)  LDD1601  [17]
 LDCM0398  CL127 HEK-293T C199(1.11)  LDD1602  [17]
 LDCM0399  CL128 HEK-293T C199(1.18)  LDD1603  [17]
 LDCM0400  CL13 HCT 116 C199(1.05)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C199(1.01)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C199(0.94)  LDD0719  [6]
 LDCM0403  CL16 HEK-293T C199(1.06)  LDD1607  [17]
 LDCM0404  CL17 HEK-293T C199(1.19)  LDD1608  [17]
 LDCM0405  CL18 HEK-293T C199(0.90)  LDD1609  [17]
 LDCM0406  CL19 HEK-293T C199(1.12)  LDD1610  [17]
 LDCM0407  CL2 HCT 116 C199(0.97)  LDD0724  [6]
 LDCM0408  CL20 HEK-293T C199(1.04)  LDD1612  [17]
 LDCM0409  CL21 HEK-293T C199(1.25)  LDD1613  [17]
 LDCM0410  CL22 HEK-293T C199(0.94)  LDD1614  [17]
 LDCM0411  CL23 HEK-293T C199(1.11)  LDD1615  [17]
 LDCM0412  CL24 HEK-293T C199(1.05)  LDD1616  [17]
 LDCM0413  CL25 HEK-293T C199(1.26)  LDD1617  [17]
 LDCM0414  CL26 HEK-293T C199(1.68)  LDD1618  [17]
 LDCM0415  CL27 HEK-293T C199(1.31)  LDD1619  [17]
 LDCM0416  CL28 HEK-293T C199(1.07)  LDD1620  [17]
 LDCM0417  CL29 HEK-293T C199(1.24)  LDD1621  [17]
 LDCM0418  CL3 HCT 116 C199(1.02)  LDD0735  [6]
 LDCM0419  CL30 HEK-293T C199(1.00)  LDD1623  [17]
 LDCM0420  CL31 HEK-293T C199(0.91)  LDD1624  [17]
 LDCM0421  CL32 HEK-293T C199(1.10)  LDD1625  [17]
 LDCM0422  CL33 HEK-293T C199(1.08)  LDD1626  [17]
 LDCM0423  CL34 HEK-293T C199(1.06)  LDD1627  [17]
 LDCM0424  CL35 HEK-293T C199(1.27)  LDD1628  [17]
 LDCM0425  CL36 HEK-293T C199(1.21)  LDD1629  [17]
 LDCM0426  CL37 HEK-293T C199(1.67)  LDD1630  [17]
 LDCM0428  CL39 HEK-293T C199(1.53)  LDD1632  [17]
 LDCM0429  CL4 HCT 116 C199(1.28)  LDD0746  [6]
 LDCM0430  CL40 HEK-293T C199(1.37)  LDD1634  [17]
 LDCM0431  CL41 HEK-293T C199(1.39)  LDD1635  [17]
 LDCM0432  CL42 HEK-293T C199(1.01)  LDD1636  [17]
 LDCM0433  CL43 HEK-293T C199(1.07)  LDD1637  [17]
 LDCM0434  CL44 HEK-293T C199(1.10)  LDD1638  [17]
 LDCM0435  CL45 HEK-293T C199(1.16)  LDD1639  [17]
 LDCM0436  CL46 HEK-293T C199(1.22)  LDD1640  [17]
 LDCM0437  CL47 HEK-293T C199(1.14)  LDD1641  [17]
 LDCM0438  CL48 HEK-293T C199(1.50)  LDD1642  [17]
 LDCM0439  CL49 HEK-293T C199(0.92)  LDD1643  [17]
 LDCM0440  CL5 HCT 116 C199(1.19)  LDD0757  [6]
 LDCM0441  CL50 HEK-293T C199(1.22)  LDD1645  [17]
 LDCM0443  CL52 HEK-293T C199(0.94)  LDD1646  [17]
 LDCM0444  CL53 HEK-293T C199(1.13)  LDD1647  [17]
 LDCM0445  CL54 HEK-293T C199(0.90)  LDD1648  [17]
 LDCM0446  CL55 HEK-293T C199(1.17)  LDD1649  [17]
 LDCM0447  CL56 HEK-293T C199(1.11)  LDD1650  [17]
 LDCM0448  CL57 HEK-293T C199(1.33)  LDD1651  [17]
 LDCM0449  CL58 HEK-293T C199(1.16)  LDD1652  [17]
 LDCM0450  CL59 HEK-293T C199(1.18)  LDD1653  [17]
 LDCM0451  CL6 HCT 116 C199(1.22)  LDD0768  [6]
 LDCM0452  CL60 HEK-293T C199(1.56)  LDD1655  [17]
 LDCM0453  CL61 HEK-293T C199(1.38)  LDD1656  [17]
 LDCM0454  CL62 HEK-293T C199(1.31)  LDD1657  [17]
 LDCM0455  CL63 HEK-293T C199(1.47)  LDD1658  [17]
 LDCM0456  CL64 HEK-293T C199(1.14)  LDD1659  [17]
 LDCM0457  CL65 HEK-293T C199(1.55)  LDD1660  [17]
 LDCM0458  CL66 HEK-293T C199(1.07)  LDD1661  [17]
 LDCM0459  CL67 HEK-293T C199(0.96)  LDD1662  [17]
 LDCM0460  CL68 HEK-293T C199(1.32)  LDD1663  [17]
 LDCM0461  CL69 HEK-293T C199(1.19)  LDD1664  [17]
 LDCM0462  CL7 HCT 116 C199(1.17)  LDD0779  [6]
 LDCM0463  CL70 HEK-293T C199(1.43)  LDD1666  [17]
 LDCM0464  CL71 HEK-293T C199(1.15)  LDD1667  [17]
 LDCM0465  CL72 HEK-293T C199(2.04)  LDD1668  [17]
 LDCM0466  CL73 HEK-293T C199(0.88)  LDD1669  [17]
 LDCM0467  CL74 HEK-293T C199(0.84)  LDD1670  [17]
 LDCM0469  CL76 HEK-293T C199(1.01)  LDD1672  [17]
 LDCM0470  CL77 HEK-293T C199(0.94)  LDD1673  [17]
 LDCM0471  CL78 HEK-293T C199(0.86)  LDD1674  [17]
 LDCM0472  CL79 HEK-293T C199(0.83)  LDD1675  [17]
 LDCM0473  CL8 HCT 116 C199(0.73)  LDD0790  [6]
 LDCM0474  CL80 HEK-293T C199(0.74)  LDD1677  [17]
 LDCM0475  CL81 HEK-293T C199(1.33)  LDD1678  [17]
 LDCM0476  CL82 HEK-293T C199(0.89)  LDD1679  [17]
 LDCM0477  CL83 HEK-293T C199(0.94)  LDD1680  [17]
 LDCM0478  CL84 HEK-293T C199(1.00)  LDD1681  [17]
 LDCM0479  CL85 HEK-293T C199(1.23)  LDD1682  [17]
 LDCM0480  CL86 HEK-293T C199(1.08)  LDD1683  [17]
 LDCM0481  CL87 HEK-293T C199(1.05)  LDD1684  [17]
 LDCM0482  CL88 HEK-293T C199(1.26)  LDD1685  [17]
 LDCM0483  CL89 HEK-293T C199(1.31)  LDD1686  [17]
 LDCM0484  CL9 HCT 116 C199(0.84)  LDD0801  [6]
 LDCM0485  CL90 HEK-293T C199(1.06)  LDD1688  [17]
 LDCM0486  CL91 HEK-293T C199(1.03)  LDD1689  [17]
 LDCM0487  CL92 HEK-293T C199(1.36)  LDD1690  [17]
 LDCM0488  CL93 HEK-293T C199(1.11)  LDD1691  [17]
 LDCM0489  CL94 HEK-293T C199(1.21)  LDD1692  [17]
 LDCM0490  CL95 HEK-293T C199(1.19)  LDD1693  [17]
 LDCM0491  CL96 HEK-293T C199(1.16)  LDD1694  [17]
 LDCM0492  CL97 HEK-293T C199(0.86)  LDD1695  [17]
 LDCM0493  CL98 HEK-293T C199(0.72)  LDD1696  [17]
 LDCM0494  CL99 HEK-293T C199(0.78)  LDD1697  [17]
 LDCM0634  CY-0357 Hep-G2 C199(3.67)  LDD2228  [14]
 LDCM0495  E2913 HEK-293T C199(1.55)  LDD1698  [17]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C199(0.75)  LDD1702  [5]
 LDCM0468  Fragment33 HEK-293T C199(0.87)  LDD1671  [17]
 LDCM0427  Fragment51 HEK-293T C199(1.50)  LDD1631  [17]
 LDCM0022  KB02 HCT 116 C199(1.95)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C199(1.27)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C199(1.56)  LDD0082  [6]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C199(0.95)  LDD2102  [5]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C199(1.10)  LDD2121  [5]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C199(0.78)  LDD2089  [5]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C199(1.16)  LDD2090  [5]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C199(1.29)  LDD2093  [5]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C199(1.12)  LDD2096  [5]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C199(0.83)  LDD2097  [5]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C199(0.81)  LDD2098  [5]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C199(1.71)  LDD2099  [5]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C199(0.23)  LDD2100  [5]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C199(1.15)  LDD2101  [5]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C199(0.55)  LDD2104  [5]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C199(1.08)  LDD2105  [5]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C199(0.39)  LDD2106  [5]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C199(1.01)  LDD2107  [5]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C199(1.04)  LDD2109  [5]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C199(0.93)  LDD2111  [5]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C199(0.49)  LDD2115  [5]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C199(0.43); C209(0.32)  LDD2116  [5]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C199(1.75)  LDD2119  [5]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C199(1.03)  LDD2120  [5]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C199(0.28)  LDD2122  [5]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C199(0.68)  LDD2123  [5]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C199(0.26); C209(0.15)  LDD2124  [5]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C199(0.98)  LDD2125  [5]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C199(0.47); C209(0.23)  LDD2126  [5]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C199(1.12)  LDD2127  [5]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C199(1.34)  LDD2129  [5]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C199(0.80)  LDD2133  [5]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C199(1.49)  LDD2135  [5]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C199(1.31)  LDD2136  [5]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C199(1.00)  LDD2137  [5]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C199(1.19)  LDD1700  [5]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C199(1.17)  LDD2140  [5]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C199(2.62)  LDD2144  [5]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C199(2.18)  LDD2145  [5]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C199(1.12)  LDD2146  [5]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C199(0.33)  LDD2149  [5]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C199(1.43)  LDD2153  [5]
 LDCM0131  RA190 MM1.R C199(1.73)  LDD0304  [18]
 LDCM0021  THZ1 HCT 116 C199(0.98)  LDD2173  [6]

References

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Mass spectrometry data entry: PXD028270
3 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells. J Am Chem Soc. 2020 Apr 1;142(13):6051-6059. doi: 10.1021/jacs.9b12116. Epub 2020 Mar 23.
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Mass spectrometry data entry: PXD042888
5 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD028853
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD033004
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14 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
15 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
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Mass spectrometry data entry: PXD044402
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