Details of the Target

General Information of Target

Target ID LDTP06330
Target Name Plectin (PLEC)
Gene Name PLEC
Gene ID 5339
Synonyms
PLEC1; Plectin; PCN; PLTN; Hemidesmosomal protein 1; HD1; Plectin-1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MVAGMLMPRDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMASLRARGL
VRETFAWCHFYWYLTNEGIAHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRTPHVQAVQ
GPLGSPPKRGPLPTEEQRVYRRKELEEVSPETPVVPATTQRTLARPGPEPAPATDERDRV
QKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRFHKLQNV
QIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSEDMTAKEK
LLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAF
SVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPDVQDGVRANELQLRWQE
YRELVLLLLQWMRHHTAAFEERRFPSSFEEIEILWSQFLKFKEMELPAKEADKNRSKGIY
QSLEGAVQAGQLKVPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVTKLQM
EAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLKDGR
HPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQVAQVTLQSVQRRPELEDSTLR
YLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIERARSDEGQLS
PATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLNEKEEEEVGFD
WSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPARPTVESFQAALQTQ
WSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDL
LQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLKPRHPAHPMRGRLPLLAVCDYKQVEVTVH
KGDECQLVGPAQPSHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVTRLEAQHQALVTLW
HQLHVDMKSLLAWQSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDA
GGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRT
VHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTL
RSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLP
ELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQ
LLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQA
VREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKP
KVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLA
EVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQ
QLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAE
EAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRL
QAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAV
AQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAE
KQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETE
QGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSE
KSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIG
EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASD
SELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE
QAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARR
LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEA
EAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAE
QEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN
LLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQ
RFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT
RLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAE
RLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH
DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL
QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE
EGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAAT
KTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELA
RREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPV
RNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGI
RLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLT
YLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVT
IWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPA
AELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNA
LKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVT
GYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCL
DEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEE
LYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEK
VIKILITIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSE
LGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVR
NQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIR
LLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTY
RQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGS
TMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYV
RRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQT
LSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLS
AERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVA
YQRGYLNKDTHDQLSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKL
TFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDAT
KERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDK
LLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPV
EVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKE
KKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITI
SSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGF
RSRSSSVGSSSSYPISPAVSRTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLV
DNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPR
TKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQ
KLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYSVSGS
GSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGSSASLGGPE
SAVA
Target Bioclass
Other
Family
Plakin or cytolinker family
Subcellular location
Cytoplasm, cytoskeleton
Function
Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.
Uniprot ID
Q15149
Ensemble ID
ENST00000322810.8
HGNC ID
HGNC:9069
ChEMBL ID
CHEMBL1293240

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 42 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		5.68  LDD0402  [1]
P8
 Probe Info  		1.82  LDD0451  [2]
CY-1
 Probe Info  		11.45  LDD0243  [3]
CY4
 Probe Info  		8.83  LDD0244  [3]
N1
 Probe Info  		12.32  LDD0242  [3]
W1
 Probe Info  		14.84  LDD0235  [4]
YN-1
 Probe Info  		100.00  LDD0444  [5]
ONAyne
 Probe Info  		K1150(10.00); K1165(3.33); K1175(1.17); K1508(10.00)  LDD0274  [6]
STPyne
 Probe Info  		K1127(0.72); K1165(6.82); K1175(10.00); K1186(9.07)  LDD0277  [6]
BTD
 Probe Info  		C530(3.04)  LDD1699  [7]
AZ-9
 Probe Info  		E1677(10.00)  LDD2208  [8]
OPA-S-S-alkyne
 Probe Info  		K2277(0.75); K4584(0.91); K2047(0.91); K4270(0.97)  LDD3494  [9]
Probe 1
 Probe Info  		Y312(19.99); Y608(9.38); Y795(37.77); Y861(17.96)  LDD3495  [10]
JZ128-DTB
 Probe Info  		C3299(0.00); C3493(0.00)  LDD0462  [11]
AHL-Pu-1
 Probe Info  		C530(2.54)  LDD0168  [12]
HHS-475
 Probe Info  		Y4615(0.69); Y396(0.80); Y4155(0.98)  LDD0264  [13]
DBIA
 Probe Info  		C3110(1.02); C3493(0.99); C3295(0.95); C317(0.89)  LDD0078  [14]
5E-2FA
 Probe Info  		H2748(0.00); H3560(0.00); H2827(0.00); H3655(0.00)  LDD2235  [15]
4-Iodoacetamidophenylacetylene
 Probe Info  		C3336(0.00); C3667(0.00); C3299(0.00); C1098(0.00)  LDD0038  [16]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [17]
Lodoacetamide azide
 Probe Info  		C4494(0.00); C317(0.00); C3336(0.00); C3667(0.00)  LDD0037  [16]
ATP probe
 Probe Info  		K4480(0.00); K1520(0.00); K2037(0.00); K1224(0.00)  LDD0035  [18]
IPM
 Probe Info  		C3667(0.00); C730(0.00); C3336(0.00); C4454(0.00)  LDD0025  [19]
JW-RF-010
 Probe Info  		C4574(0.00); C3667(0.00); C3493(0.00); C4454(0.00)  LDD0026  [19]
NAIA_4
 Probe Info  		C950(0.00); C992(0.00); C1098(0.00); C1136(0.00)  LDD2226  [20]
TFBX
 Probe Info  		C3667(0.00); C3295(0.00); C1136(0.00); C1122(0.00)  LDD0027  [19]
WYneN
 Probe Info  		C530(0.00); C4494(0.00); C4245(0.00); C3110(0.00)  LDD0021  [21]
WYneO
 Probe Info  		C965(0.00); C4494(0.00); C3295(0.00); C950(0.00)  LDD0022  [21]
Compound 10
 Probe Info  		N.A.  LDD2216  [22]
Compound 11
 Probe Info  		N.A.  LDD2213  [22]
ENE
 Probe Info  		N.A.  LDD0006  [21]
NPM
 Probe Info  		N.A.  LDD0016  [21]
SF
 Probe Info  		N.A.  LDD0028  [23]
VSF
 Probe Info  		C530(0.00); C3336(0.00)  LDD0007  [21]
Phosphinate-6
 Probe Info  		C1405(0.00); C4574(0.00)  LDD0018  [24]
Acrolein
 Probe Info  		C545(0.00); H3971(0.00); H2959(0.00); H2748(0.00)  LDD0217  [25]
Cinnamaldehyde
 Probe Info  		C1136(0.00); C4494(0.00); C530(0.00)  LDD0220  [25]
Crotonaldehyde
 Probe Info  		H2957(0.00); H2959(0.00); H2813(0.00); H2748(0.00)  LDD0219  [25]
Methacrolein
 Probe Info  		C4454(0.00); C3295(0.00); C1405(0.00); C1136(0.00)  LDD0218  [25]
NAIA_5
 Probe Info  		C4494(0.00); C317(0.00); C1122(0.00); C3336(0.00)  LDD2223  [20]
HHS-465
 Probe Info  		K4158(0.00); Y4155(0.00); Y498(0.00); Y396(0.00)  LDD2240  [26]
HHS-482
 Probe Info  		Y3069(1.24); Y3134(0.52); Y3545(0.72); Y3695(0.75)  LDD2239  [27]
PAL-AfBPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe12
 Probe Info  		20.00  LDD0474  [28]
FFF probe13
 Probe Info  		5.55  LDD0476  [28]
FFF probe3
 Probe Info  		20.00  LDD0465  [28]
STS-1
 Probe Info  		N.A.  LDD0136  [29]
STS-2
 Probe Info  		7.50  LDD0138  [29]
DA-2
 Probe Info  		N.A.  LDD0071  [30]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C3295(0.53); C1136(0.23); C4454(0.52); C4574(0.44)  LDD2142  [7]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C3295(0.65); C3299(0.62); C1156(0.46); C4454(0.92)  LDD2112  [7]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C3295(0.47); C3299(0.39); C1136(0.31); C1156(0.30)  LDD2095  [7]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C3295(0.60); C3299(0.35); C3110(0.50)  LDD2130  [7]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C3295(0.97); C1136(1.27); C1156(0.57); C4454(1.03)  LDD2117  [7]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C3295(1.66); C1136(1.81); C1156(2.30); C4574(1.74)  LDD2152  [7]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C3295(1.04); C1156(1.01); C4574(0.98); C3110(0.81)  LDD2103  [7]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C3295(0.38); C1156(0.77); C3110(0.42)  LDD2132  [7]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C4574(0.71); C3336(1.01)  LDD2131  [7]
 LDCM0025  4SU-RNA HEK-293T C530(2.54)  LDD0168  [12]
 LDCM0026  4SU-RNA+native RNA HEK-293T C530(4.58); C4494(2.67); C1122(2.42)  LDD0169  [12]
 LDCM0214  AC1 HEK-293T C3110(1.10); C4494(0.93)  LDD0812  [14]
 LDCM0215  AC10 HEK-293T C3110(1.13); C317(1.00); C4071(0.95); C4494(0.78)  LDD0813  [14]
 LDCM0216  AC100 HEK-293T C3008(0.93); C3017(0.93); C3110(1.36); C317(0.75)  LDD0814  [14]
 LDCM0217  AC101 HEK-293T C3008(0.86); C3017(0.86); C3110(1.79); C317(1.09)  LDD0815  [14]
 LDCM0218  AC102 HEK-293T C3008(0.95); C3017(0.95); C3110(1.63); C317(0.71)  LDD0816  [14]
 LDCM0219  AC103 HEK-293T C3008(1.07); C3017(1.07); C3110(1.19); C317(0.74)  LDD0817  [14]
 LDCM0220  AC104 HEK-293T C3008(1.19); C3017(1.19); C3110(1.17); C317(0.75)  LDD0818  [14]
 LDCM0221  AC105 HEK-293T C3008(0.95); C3017(0.95); C3110(1.47); C317(1.83)  LDD0819  [14]
 LDCM0222  AC106 HEK-293T C3008(0.72); C3017(0.72); C3110(1.61); C317(2.27)  LDD0820  [14]
 LDCM0223  AC107 HEK-293T C3008(0.93); C3017(0.93); C3110(1.70); C317(0.87)  LDD0821  [14]
 LDCM0224  AC108 HEK-293T C3008(0.85); C3017(0.85); C3110(1.45); C317(1.65)  LDD0822  [14]
 LDCM0225  AC109 HEK-293T C3008(0.95); C3017(0.95); C3110(1.22); C317(0.83)  LDD0823  [14]
 LDCM0226  AC11 HEK-293T C3110(0.97); C317(1.49); C4071(1.02); C4494(0.76)  LDD0824  [14]
 LDCM0227  AC110 HEK-293T C3008(1.06); C3017(1.06); C3110(1.58); C317(0.67)  LDD0825  [14]
 LDCM0228  AC111 HEK-293T C3008(1.57); C3017(1.57); C3110(1.15); C317(0.72)  LDD0826  [14]
 LDCM0229  AC112 HEK-293T C3008(1.26); C3017(1.26); C3110(1.24); C317(0.49)  LDD0827  [14]
 LDCM0230  AC113 HEK-293T C3008(0.99); C3017(0.99); C317(0.91); C4494(1.21)  LDD0828  [14]
 LDCM0231  AC114 HEK-293T C3008(0.87); C3017(0.87); C317(0.72); C4494(1.17)  LDD0829  [14]
 LDCM0232  AC115 HEK-293T C3008(0.97); C3017(0.97); C317(0.77); C4494(1.16)  LDD0830  [14]
 LDCM0233  AC116 HEK-293T C3008(1.11); C3017(1.11); C317(0.65); C4494(1.39)  LDD0831  [14]
 LDCM0234  AC117 HEK-293T C3008(1.06); C3017(1.06); C317(0.56); C4494(1.19)  LDD0832  [14]
 LDCM0235  AC118 HEK-293T C3008(0.88); C3017(0.88); C317(0.68); C4494(1.37)  LDD0833  [14]
 LDCM0236  AC119 HEK-293T C3008(1.18); C3017(1.18); C317(0.50); C4494(1.38)  LDD0834  [14]
 LDCM0237  AC12 HEK-293T C3110(1.02); C317(0.86); C4071(1.01); C4494(0.96)  LDD0835  [14]
 LDCM0238  AC120 HEK-293T C3008(1.54); C3017(1.54); C317(0.90); C4494(1.47)  LDD0836  [14]
 LDCM0239  AC121 HEK-293T C3008(1.01); C3017(1.01); C317(0.36); C4494(1.52)  LDD0837  [14]
 LDCM0240  AC122 HEK-293T C3008(1.48); C3017(1.48); C317(0.37); C4494(1.91)  LDD0838  [14]
 LDCM0241  AC123 HEK-293T C3008(1.33); C3017(1.33); C317(0.48); C4494(1.73)  LDD0839  [14]
 LDCM0242  AC124 HEK-293T C3008(1.17); C3017(1.17); C317(0.65); C4494(1.34)  LDD0840  [14]
 LDCM0243  AC125 HEK-293T C3008(1.36); C3017(1.36); C317(0.38); C4494(1.70)  LDD0841  [14]
 LDCM0244  AC126 HEK-293T C3008(1.51); C3017(1.51); C317(0.43); C4494(1.87)  LDD0842  [14]
 LDCM0245  AC127 HEK-293T C3008(1.72); C3017(1.72); C317(0.40); C4494(1.73)  LDD0843  [14]
 LDCM0246  AC128 HEK-293T C3110(0.92); C4494(1.02)  LDD0844  [14]
 LDCM0247  AC129 HEK-293T C3110(1.09); C4494(1.29)  LDD0845  [14]
 LDCM0249  AC130 HEK-293T C3110(0.91); C4494(1.51)  LDD0847  [14]
 LDCM0250  AC131 HEK-293T C3110(1.08); C4494(0.90)  LDD0848  [14]
 LDCM0251  AC132 HEK-293T C3110(1.22); C4494(1.11)  LDD0849  [14]
 LDCM0252  AC133 HEK-293T C3110(0.95); C4494(1.36)  LDD0850  [14]
 LDCM0253  AC134 HEK-293T C3110(0.78); C4494(1.08)  LDD0851  [14]
 LDCM0254  AC135 HEK-293T C3110(0.93); C4494(1.20)  LDD0852  [14]
 LDCM0255  AC136 HEK-293T C3110(0.80); C4494(1.30)  LDD0853  [14]
 LDCM0256  AC137 HEK-293T C3110(1.02); C4494(1.34)  LDD0854  [14]
 LDCM0257  AC138 HEK-293T C3110(0.82); C4494(1.21)  LDD0855  [14]
 LDCM0258  AC139 HEK-293T C3110(0.91); C4494(1.31)  LDD0856  [14]
 LDCM0259  AC14 HEK-293T C3110(1.10); C317(0.89); C4071(1.31); C4494(0.91)  LDD0857  [14]
 LDCM0260  AC140 HEK-293T C3110(0.96); C4494(1.11)  LDD0858  [14]
 LDCM0261  AC141 HEK-293T C3110(0.88); C4494(1.21)  LDD0859  [14]
 LDCM0262  AC142 HEK-293T C3110(0.96); C4494(1.19)  LDD0860  [14]
 LDCM0263  AC143 HEK-293T C3008(1.07); C3017(1.07); C3110(0.96); C317(0.83)  LDD0861  [14]
 LDCM0264  AC144 HEK-293T C3008(1.09); C3017(1.09); C3110(0.83); C317(0.87)  LDD0862  [14]
 LDCM0265  AC145 HEK-293T C3008(1.17); C3017(1.17); C3110(0.95); C317(1.06)  LDD0863  [14]
 LDCM0266  AC146 HEK-293T C3008(1.63); C3017(1.63); C3110(0.87); C317(0.94)  LDD0864  [14]
 LDCM0267  AC147 HEK-293T C3008(1.82); C3017(1.82); C3110(0.89); C317(0.86)  LDD0865  [14]
 LDCM0268  AC148 HEK-293T C3008(1.50); C3017(1.50); C3110(0.94); C317(0.67)  LDD0866  [14]
 LDCM0269  AC149 HEK-293T C3008(1.05); C3017(1.05); C3110(1.10); C317(1.21)  LDD0867  [14]
 LDCM0270  AC15 HEK-293T C3110(1.21); C317(0.78); C4071(1.26); C4494(1.23)  LDD0868  [14]
 LDCM0271  AC150 HEK-293T C3008(1.23); C3017(1.23); C3110(0.90); C317(0.99)  LDD0869  [14]
 LDCM0272  AC151 HEK-293T C3008(1.28); C3017(1.28); C3110(1.01); C317(1.15)  LDD0870  [14]
 LDCM0273  AC152 HEK-293T C3008(1.31); C3017(1.31); C3110(1.06); C317(0.92)  LDD0871  [14]
 LDCM0274  AC153 HEK-293T C3008(1.18); C3017(1.18); C3110(0.84); C317(0.89)  LDD0872  [14]
 LDCM0621  AC154 HEK-293T C3008(1.15); C3017(1.15); C3110(1.03); C317(0.75)  LDD2162  [14]
 LDCM0622  AC155 HEK-293T C3008(1.24); C3017(1.24); C3110(0.91); C317(1.04)  LDD2163  [14]
 LDCM0623  AC156 HEK-293T C3008(1.79); C3017(1.79); C3110(0.81); C317(0.94)  LDD2164  [14]
 LDCM0624  AC157 HEK-293T C3008(1.61); C3017(1.61); C3110(0.96); C317(0.83)  LDD2165  [14]
 LDCM0276  AC17 HEK-293T C3008(1.47); C3017(1.47); C317(0.60); C4494(1.53)  LDD0874  [14]
 LDCM0277  AC18 HEK-293T C3008(1.39); C3017(1.39); C317(0.66); C4494(1.30)  LDD0875  [14]
 LDCM0278  AC19 HEK-293T C3008(1.35); C3017(1.35); C317(0.81); C4494(1.09)  LDD0876  [14]
 LDCM0279  AC2 HEK-293T C3110(0.84); C4494(1.01)  LDD0877  [14]
 LDCM0280  AC20 HEK-293T C3008(1.56); C3017(1.56); C317(0.76); C4494(1.41)  LDD0878  [14]
 LDCM0281  AC21 HEK-293T C3008(1.52); C3017(1.52); C317(1.02); C4494(1.51)  LDD0879  [14]
 LDCM0282  AC22 HEK-293T C3008(1.37); C3017(1.37); C317(0.69); C4494(1.33)  LDD0880  [14]
 LDCM0283  AC23 HEK-293T C3008(2.05); C3017(2.05); C317(0.88); C4494(1.98)  LDD0881  [14]
 LDCM0284  AC24 HEK-293T C3008(1.26); C3017(1.26); C317(1.18); C4494(1.08)  LDD0882  [14]
 LDCM0285  AC25 HEK-293T C3110(1.09); C317(0.43); C3295(0.99); C4494(1.18)  LDD0883  [14]
 LDCM0286  AC26 HEK-293T C3110(1.16); C317(0.55); C3295(1.11); C4494(1.45)  LDD0884  [14]
 LDCM0287  AC27 HEK-293T C3110(1.15); C317(0.57); C3295(1.21); C4494(1.33)  LDD0885  [14]
 LDCM0288  AC28 HEK-293T C3110(1.02); C317(0.27); C3295(1.03); C4494(1.85)  LDD0886  [14]
 LDCM0289  AC29 HEK-293T C3110(1.00); C317(0.32); C3295(1.20); C4494(1.35)  LDD0887  [14]
 LDCM0290  AC3 HEK-293T C3110(1.04); C4494(0.79)  LDD0888  [14]
 LDCM0291  AC30 HEK-293T C3110(1.35); C317(0.73); C3295(1.11); C4494(1.33)  LDD0889  [14]
 LDCM0292  AC31 HEK-293T C3110(1.29); C317(0.50); C3295(1.00); C4494(1.18)  LDD0890  [14]
 LDCM0293  AC32 HEK-293T C3110(0.97); C317(0.52); C3295(1.06); C4494(1.26)  LDD0891  [14]
 LDCM0294  AC33 HEK-293T C3110(1.00); C317(0.50); C3295(1.17); C4494(1.21)  LDD0892  [14]
 LDCM0295  AC34 HEK-293T C3110(1.18); C317(0.61); C3295(1.12); C4494(1.19)  LDD0893  [14]
 LDCM0296  AC35 HEK-293T C3008(1.49); C3017(1.49); C3110(0.76); C3295(1.07)  LDD0894  [14]
 LDCM0297  AC36 HEK-293T C3008(1.42); C3017(1.42); C3110(0.52); C3295(1.08)  LDD0895  [14]
 LDCM0298  AC37 HEK-293T C3008(1.52); C3017(1.52); C3110(0.75); C3295(1.24)  LDD0896  [14]
 LDCM0299  AC38 HEK-293T C3008(1.17); C3017(1.17); C3110(1.04); C3295(1.09)  LDD0897  [14]
 LDCM0300  AC39 HEK-293T C3008(1.26); C3017(1.26); C3110(0.83); C3295(1.19)  LDD0898  [14]
 LDCM0301  AC4 HEK-293T C3110(1.14); C4494(0.78)  LDD0899  [14]
 LDCM0302  AC40 HEK-293T C3008(1.08); C3017(1.08); C3110(0.94); C3295(0.99)  LDD0900  [14]
 LDCM0303  AC41 HEK-293T C3008(1.45); C3017(1.45); C3110(0.97); C3295(0.99)  LDD0901  [14]
 LDCM0304  AC42 HEK-293T C3008(1.39); C3017(1.39); C3110(0.84); C3295(1.19)  LDD0902  [14]
 LDCM0305  AC43 HEK-293T C3008(1.02); C3017(1.02); C3110(1.12); C3295(1.11)  LDD0903  [14]
 LDCM0306  AC44 HEK-293T C3008(1.22); C3017(1.22); C3110(0.81); C3295(1.22)  LDD0904  [14]
 LDCM0307  AC45 HEK-293T C3008(1.24); C3017(1.24); C3110(0.83); C3295(1.07)  LDD0905  [14]
 LDCM0308  AC46 HEK-293T C3008(0.72); C3017(0.72); C3110(0.88); C317(0.41)  LDD0906  [14]
 LDCM0309  AC47 HEK-293T C3008(0.96); C3017(0.96); C3110(0.64); C317(0.67)  LDD0907  [14]
 LDCM0310  AC48 HEK-293T C3008(0.80); C3017(0.80); C3110(0.74); C317(1.11)  LDD0908  [14]
 LDCM0311  AC49 HEK-293T C3008(1.52); C3017(1.52); C3110(0.74); C317(0.82)  LDD0909  [14]
 LDCM0312  AC5 HEK-293T C3110(1.12); C4494(0.91)  LDD0910  [14]
 LDCM0313  AC50 HEK-293T C3008(0.96); C3017(0.96); C3110(0.99); C317(0.70)  LDD0911  [14]
 LDCM0314  AC51 HEK-293T C3008(1.02); C3017(1.02); C3110(0.94); C317(1.12)  LDD0912  [14]
 LDCM0315  AC52 HEK-293T C3008(0.96); C3017(0.96); C3110(0.78); C317(0.94)  LDD0913  [14]
 LDCM0316  AC53 HEK-293T C3008(0.77); C3017(0.77); C3110(1.29); C317(1.00)  LDD0914  [14]
 LDCM0317  AC54 HEK-293T C3008(0.96); C3017(0.96); C3110(0.91); C317(0.87)  LDD0915  [14]
 LDCM0318  AC55 HEK-293T C3008(0.85); C3017(0.85); C3110(1.26); C317(1.51)  LDD0916  [14]
 LDCM0319  AC56 HEK-293T C3008(0.83); C3017(0.83); C3110(1.07); C317(0.95)  LDD0917  [14]
 LDCM0320  AC57 HEK-293T C3008(1.17); C3017(1.17); C3110(0.85); C317(1.08)  LDD0918  [14]
 LDCM0321  AC58 HEK-293T C3008(0.82); C3017(0.82); C3110(0.91); C317(0.88)  LDD0919  [14]
 LDCM0322  AC59 HEK-293T C3008(0.88); C3017(0.88); C3110(0.89); C317(1.24)  LDD0920  [14]
 LDCM0323  AC6 HEK-293T C3110(1.03); C317(0.21); C4071(0.58); C4494(0.80)  LDD0921  [14]
 LDCM0324  AC60 HEK-293T C3008(1.33); C3017(1.33); C3110(1.15); C317(0.95)  LDD0922  [14]
 LDCM0325  AC61 HEK-293T C3008(1.09); C3017(1.09); C3110(1.07); C317(1.24)  LDD0923  [14]
 LDCM0326  AC62 HEK-293T C3008(0.94); C3017(0.94); C3110(0.98); C317(1.38)  LDD0924  [14]
 LDCM0327  AC63 HEK-293T C3008(1.02); C3017(1.02); C3110(0.91); C317(1.03)  LDD0925  [14]
 LDCM0328  AC64 HEK-293T C3008(0.96); C3017(0.96); C3110(0.80); C317(1.00)  LDD0926  [14]
 LDCM0329  AC65 HEK-293T C3008(1.00); C3017(1.00); C3110(0.89); C317(0.87)  LDD0927  [14]
 LDCM0330  AC66 HEK-293T C3008(0.81); C3017(0.81); C3110(0.78); C317(1.31)  LDD0928  [14]
 LDCM0331  AC67 HEK-293T C3008(0.92); C3017(0.92); C3110(0.81); C317(0.95)  LDD0929  [14]
 LDCM0332  AC68 HEK-293T C3110(1.10); C317(1.18); C3295(1.12); C4494(0.97)  LDD0930  [14]
 LDCM0333  AC69 HEK-293T C3110(0.98); C317(1.16); C3295(1.06); C4494(1.00)  LDD0931  [14]
 LDCM0334  AC7 HEK-293T C3110(0.84); C317(1.55); C4071(0.83); C4494(0.96)  LDD0932  [14]
 LDCM0335  AC70 HEK-293T C3110(1.01); C317(0.68); C3295(1.21); C4494(1.06)  LDD0933  [14]
 LDCM0336  AC71 HEK-293T C3110(0.95); C317(0.93); C3295(1.18); C4494(1.10)  LDD0934  [14]
 LDCM0337  AC72 HEK-293T C3110(1.00); C317(0.90); C3295(1.13); C4494(1.14)  LDD0935  [14]
 LDCM0338  AC73 HEK-293T C3110(1.33); C317(0.82); C3295(1.25); C4494(1.30)  LDD0936  [14]
 LDCM0339  AC74 HEK-293T C3110(1.06); C317(0.91); C3295(1.28); C4494(1.00)  LDD0937  [14]
 LDCM0340  AC75 HEK-293T C3110(1.00); C317(0.89); C3295(1.13); C4494(1.10)  LDD0938  [14]
 LDCM0341  AC76 HEK-293T C3110(1.14); C317(1.32); C3295(1.21); C4494(1.12)  LDD0939  [14]
 LDCM0342  AC77 HEK-293T C3110(0.93); C317(1.33); C3295(1.21); C4494(0.99)  LDD0940  [14]
 LDCM0343  AC78 HEK-293T C3110(1.09); C317(0.90); C3295(1.22); C4494(1.08)  LDD0941  [14]
 LDCM0344  AC79 HEK-293T C3110(0.91); C317(0.96); C3295(1.13); C4494(0.92)  LDD0942  [14]
 LDCM0345  AC8 HEK-293T C3110(0.89); C317(1.41); C4071(0.80); C4494(1.09)  LDD0943  [14]
 LDCM0346  AC80 HEK-293T C3110(1.05); C317(0.83); C3295(1.28); C4494(0.99)  LDD0944  [14]
 LDCM0347  AC81 HEK-293T C3110(0.97); C317(1.49); C3295(1.13); C4494(0.97)  LDD0945  [14]
 LDCM0348  AC82 HEK-293T C3110(0.99); C317(0.77); C3295(1.47); C4494(1.07)  LDD0946  [14]
 LDCM0349  AC83 HEK-293T C3008(0.93); C3017(0.93); C3110(0.98); C317(0.60)  LDD0947  [14]
 LDCM0350  AC84 HEK-293T C3008(0.97); C3017(0.97); C3110(0.97); C317(0.67)  LDD0948  [14]
 LDCM0351  AC85 HEK-293T C3008(0.96); C3017(0.96); C3110(0.78); C317(0.88)  LDD0949  [14]
 LDCM0352  AC86 HEK-293T C3008(0.90); C3017(0.90); C3110(1.05); C317(0.68)  LDD0950  [14]
 LDCM0353  AC87 HEK-293T C3008(0.99); C3017(0.99); C3110(0.92); C317(0.90)  LDD0951  [14]
 LDCM0354  AC88 HEK-293T C3008(0.89); C3017(0.89); C3110(1.15); C317(0.62)  LDD0952  [14]
 LDCM0355  AC89 HEK-293T C3008(1.14); C3017(1.14); C3110(0.92); C317(0.55)  LDD0953  [14]
 LDCM0357  AC90 HEK-293T C3008(1.12); C3017(1.12); C3110(1.00); C317(0.62)  LDD0955  [14]
 LDCM0358  AC91 HEK-293T C3008(0.98); C3017(0.98); C3110(0.79); C317(0.67)  LDD0956  [14]
 LDCM0359  AC92 HEK-293T C3008(0.82); C3017(0.82); C3110(0.93); C317(1.01)  LDD0957  [14]
 LDCM0360  AC93 HEK-293T C3008(1.13); C3017(1.13); C3110(0.83); C317(0.77)  LDD0958  [14]
 LDCM0361  AC94 HEK-293T C3008(1.52); C3017(1.52); C3110(1.02); C317(0.63)  LDD0959  [14]
 LDCM0362  AC95 HEK-293T C3008(1.01); C3017(1.01); C3110(0.93); C317(0.65)  LDD0960  [14]
 LDCM0363  AC96 HEK-293T C3008(1.05); C3017(1.05); C3110(0.91); C317(0.49)  LDD0961  [14]
 LDCM0364  AC97 HEK-293T C3008(1.48); C3017(1.48); C3110(0.97); C317(0.44)  LDD0962  [14]
 LDCM0365  AC98 HEK-293T C3008(1.10); C3017(1.10); C3110(1.14); C317(1.10)  LDD0963  [14]
 LDCM0366  AC99 HEK-293T C3008(0.77); C3017(0.77); C3110(1.12); C317(1.56)  LDD0964  [14]
 LDCM0545  Acetamide MDA-MB-231 C3295(0.45); C3299(0.62); C1156(0.23); C4574(0.32)  LDD2138  [7]
 LDCM0520  AKOS000195272 MDA-MB-231 C3295(0.77); C4574(0.79); C3110(0.91); C530(0.70)  LDD2113  [7]
 LDCM0248  AKOS034007472 HEK-293T C3110(1.07); C317(0.97); C4071(0.90); C4494(1.00)  LDD0846  [14]
 LDCM0356  AKOS034007680 HEK-293T C3110(0.99); C317(1.20); C4071(1.37); C4494(1.10)  LDD0954  [14]
 LDCM0275  AKOS034007705 HEK-293T C3110(1.19); C317(0.81); C4071(0.89); C4494(1.14)  LDD0873  [14]
 LDCM0156  Aniline NCI-H1299 C3821(0.00); C992(0.00); C4071(0.00); C3295(0.00)  LDD0404  [1]
 LDCM0020  ARS-1620 HCC44 C3110(1.02); C3493(0.99); C3295(0.95); C317(0.89)  LDD0078  [14]
 LDCM0498  BS-3668 MDA-MB-231 C3295(0.53); C1136(0.51); C1156(0.24); C4454(0.55)  LDD2091  [7]
 LDCM0630  CCW28-3 231MFP C950(2.09); C992(2.01); C3295(1.40); C3821(1.32)  LDD2214  [31]
 LDCM0108  Chloroacetamide HeLa C1098(0.00); C545(0.00); C4454(0.00); H2996(0.00)  LDD0222  [25]
 LDCM0632  CL-Sc Hep-G2 C3110(1.78); C3336(0.92); C3295(0.91); C950(0.91)  LDD2227  [20]
 LDCM0367  CL1 HEK-293T C317(0.20); C4494(1.67)  LDD0965  [14]
 LDCM0368  CL10 HEK-293T C317(0.12); C4494(2.06)  LDD0966  [14]
 LDCM0369  CL100 HEK-293T C3110(1.14); C4494(1.22)  LDD0967  [14]
 LDCM0370  CL101 HEK-293T C3110(1.01); C317(0.82); C4071(0.87); C4494(1.39)  LDD0968  [14]
 LDCM0371  CL102 HEK-293T C3110(1.04); C317(0.91); C4071(1.20); C4494(1.36)  LDD0969  [14]
 LDCM0372  CL103 HEK-293T C3110(1.03); C317(1.70); C4071(1.16); C4494(1.07)  LDD0970  [14]
 LDCM0373  CL104 HEK-293T C3110(1.13); C317(0.84); C4071(1.06); C4494(1.23)  LDD0971  [14]
 LDCM0374  CL105 HEK-293T C3008(1.30); C3017(1.30); C317(0.93); C4494(1.21)  LDD0972  [14]
 LDCM0375  CL106 HEK-293T C3008(1.59); C3017(1.59); C317(1.23); C4494(1.21)  LDD0973  [14]
 LDCM0376  CL107 HEK-293T C3008(1.18); C3017(1.18); C317(0.72); C4494(1.28)  LDD0974  [14]
 LDCM0377  CL108 HEK-293T C3008(1.38); C3017(1.38); C317(0.62); C4494(1.24)  LDD0975  [14]
 LDCM0378  CL109 HEK-293T C3008(1.65); C3017(1.65); C317(0.74); C4494(1.19)  LDD0976  [14]
 LDCM0379  CL11 HEK-293T C317(0.12); C4494(1.90)  LDD0977  [14]
 LDCM0380  CL110 HEK-293T C3008(1.93); C3017(1.93); C317(0.66); C4494(1.45)  LDD0978  [14]
 LDCM0381  CL111 HEK-293T C3008(1.68); C3017(1.68); C317(1.21); C4494(1.29)  LDD0979  [14]
 LDCM0382  CL112 HEK-293T C3110(1.00); C317(0.30); C3295(1.19); C4494(1.54)  LDD0980  [14]
 LDCM0383  CL113 HEK-293T C3110(1.18); C317(0.43); C3295(1.15); C4494(1.31)  LDD0981  [14]
 LDCM0384  CL114 HEK-293T C3110(0.75); C317(0.35); C3295(1.66); C4494(1.98)  LDD0982  [14]
 LDCM0385  CL115 HEK-293T C3110(1.12); C317(0.53); C3295(1.04); C4494(1.34)  LDD0983  [14]
 LDCM0386  CL116 HEK-293T C3110(1.37); C317(0.32); C3295(1.26); C4494(1.38)  LDD0984  [14]
 LDCM0387  CL117 HEK-293T C3008(1.42); C3017(1.42); C3110(1.02); C3295(1.08)  LDD0985  [14]
 LDCM0388  CL118 HEK-293T C3008(1.30); C3017(1.30); C3110(0.74); C3295(1.17)  LDD0986  [14]
 LDCM0389  CL119 HEK-293T C3008(1.10); C3017(1.10); C3110(0.81); C3295(1.05)  LDD0987  [14]
 LDCM0390  CL12 HEK-293T C317(0.30); C4494(1.25)  LDD0988  [14]
 LDCM0391  CL120 HEK-293T C3008(1.29); C3017(1.29); C3110(0.85); C3295(1.14)  LDD0989  [14]
 LDCM0392  CL121 HEK-293T C3008(0.87); C3017(0.87); C3110(0.83); C317(1.60)  LDD0990  [14]
 LDCM0393  CL122 HEK-293T C3008(0.88); C3017(0.88); C3110(0.71); C317(1.24)  LDD0991  [14]
 LDCM0394  CL123 HEK-293T C3008(1.07); C3017(1.07); C3110(0.85); C317(1.01)  LDD0992  [14]
 LDCM0395  CL124 HEK-293T C3008(0.98); C3017(0.98); C3110(1.03); C317(1.12)  LDD0993  [14]
 LDCM0396  CL125 HEK-293T C3008(1.14); C3017(1.14); C3110(0.76); C317(1.50)  LDD0994  [14]
 LDCM0397  CL126 HEK-293T C3008(1.13); C3017(1.13); C3110(0.94); C317(0.83)  LDD0995  [14]
 LDCM0398  CL127 HEK-293T C3008(1.13); C3017(1.13); C3110(1.17); C317(1.10)  LDD0996  [14]
 LDCM0399  CL128 HEK-293T C3008(0.92); C3017(0.92); C3110(0.80); C317(1.33)  LDD0997  [14]
 LDCM0400  CL13 HEK-293T C317(0.48); C4494(1.08)  LDD0998  [14]
 LDCM0401  CL14 HEK-293T C317(0.33); C4494(1.34)  LDD0999  [14]
 LDCM0402  CL15 HEK-293T C317(0.24); C4494(1.79)  LDD1000  [14]
 LDCM0403  CL16 HEK-293T C3008(0.98); C3017(0.98); C317(1.27); C3295(0.90)  LDD1001  [14]
 LDCM0404  CL17 HEK-293T C3008(1.75); C3017(1.75); C317(0.83); C3295(0.84)  LDD1002  [14]
 LDCM0405  CL18 HEK-293T C3008(1.22); C3017(1.22); C317(1.13); C3295(0.85)  LDD1003  [14]
 LDCM0406  CL19 HEK-293T C3008(1.04); C3017(1.04); C317(1.11); C3295(1.00)  LDD1004  [14]
 LDCM0407  CL2 HEK-293T C317(0.27); C4494(1.50)  LDD1005  [14]
 LDCM0408  CL20 HEK-293T C3008(1.21); C3017(1.21); C317(1.09); C3295(0.88)  LDD1006  [14]
 LDCM0409  CL21 HEK-293T C3008(3.75); C3017(3.75); C317(0.82); C3295(1.06)  LDD1007  [14]
 LDCM0410  CL22 HEK-293T C3008(1.40); C3017(1.40); C317(1.13); C3295(0.98)  LDD1008  [14]
 LDCM0411  CL23 HEK-293T C3008(1.48); C3017(1.48); C317(1.46); C3295(0.84)  LDD1009  [14]
 LDCM0412  CL24 HEK-293T C3008(1.16); C3017(1.16); C317(0.96); C3295(0.98)  LDD1010  [14]
 LDCM0413  CL25 HEK-293T C3008(1.48); C3017(1.48); C317(0.87); C3295(0.69)  LDD1011  [14]
 LDCM0414  CL26 HEK-293T C3008(1.14); C3017(1.14); C317(1.23); C3295(1.12)  LDD1012  [14]
 LDCM0415  CL27 HEK-293T C3008(1.12); C3017(1.12); C317(0.97); C3295(1.06)  LDD1013  [14]
 LDCM0416  CL28 HEK-293T C3008(1.45); C3017(1.45); C317(1.21); C3295(0.89)  LDD1014  [14]
 LDCM0417  CL29 HEK-293T C3008(1.29); C3017(1.29); C317(0.93); C3295(0.96)  LDD1015  [14]
 LDCM0418  CL3 HEK-293T C317(0.26); C4494(1.68)  LDD1016  [14]
 LDCM0419  CL30 HEK-293T C3008(1.53); C3017(1.53); C317(0.92); C3295(0.83)  LDD1017  [14]
 LDCM0420  CL31 HEK-293T C3008(1.01); C3017(1.01); C3110(1.17); C317(1.19)  LDD1018  [14]
 LDCM0421  CL32 HEK-293T C3008(1.06); C3017(1.06); C3110(1.20); C317(1.06)  LDD1019  [14]
 LDCM0422  CL33 HEK-293T C3008(2.17); C3017(2.17); C3110(0.82); C317(0.67)  LDD1020  [14]
 LDCM0423  CL34 HEK-293T C3008(1.27); C3017(1.27); C3110(1.12); C317(0.98)  LDD1021  [14]
 LDCM0424  CL35 HEK-293T C3008(1.06); C3017(1.06); C3110(1.28); C317(1.13)  LDD1022  [14]
 LDCM0425  CL36 HEK-293T C3008(1.15); C3017(1.15); C3110(0.94); C317(1.33)  LDD1023  [14]
 LDCM0426  CL37 HEK-293T C3008(1.20); C3017(1.20); C3110(1.03); C317(0.87)  LDD1024  [14]
 LDCM0428  CL39 HEK-293T C3008(2.06); C3017(2.06); C3110(0.88); C317(0.65)  LDD1026  [14]
 LDCM0429  CL4 HEK-293T C317(0.25); C4494(1.22)  LDD1027  [14]
 LDCM0430  CL40 HEK-293T C3008(1.15); C3017(1.15); C3110(1.21); C317(0.78)  LDD1028  [14]
 LDCM0431  CL41 HEK-293T C3008(1.71); C3017(1.71); C3110(0.96); C317(0.77)  LDD1029  [14]
 LDCM0432  CL42 HEK-293T C3008(1.32); C3017(1.32); C3110(1.18); C317(0.74)  LDD1030  [14]
 LDCM0433  CL43 HEK-293T C3008(1.52); C3017(1.52); C3110(1.28); C317(1.02)  LDD1031  [14]
 LDCM0434  CL44 HEK-293T C3008(1.09); C3017(1.09); C3110(1.24); C317(1.41)  LDD1032  [14]
 LDCM0435  CL45 HEK-293T C3008(1.84); C3017(1.84); C3110(1.04); C317(0.61)  LDD1033  [14]
 LDCM0436  CL46 HEK-293T C3008(1.12); C3017(1.12); C3110(0.90); C4071(0.63)  LDD1034  [14]
 LDCM0437  CL47 HEK-293T C3008(0.97); C3017(0.97); C3110(0.94); C4071(0.67)  LDD1035  [14]
 LDCM0438  CL48 HEK-293T C3008(0.85); C3017(0.85); C3110(0.98); C4071(0.59)  LDD1036  [14]
 LDCM0439  CL49 HEK-293T C3008(1.05); C3017(1.05); C3110(0.77); C4071(0.96)  LDD1037  [14]
 LDCM0440  CL5 HEK-293T C317(0.37); C4494(1.40)  LDD1038  [14]
 LDCM0441  CL50 HEK-293T C3008(1.62); C3017(1.62); C3110(0.75); C4071(1.18)  LDD1039  [14]
 LDCM0442  CL51 HEK-293T C3008(1.67); C3017(1.67); C3110(0.91); C4071(1.17)  LDD1040  [14]
 LDCM0443  CL52 HEK-293T C3008(0.83); C3017(0.83); C3110(1.10); C4071(0.76)  LDD1041  [14]
 LDCM0444  CL53 HEK-293T C3008(1.49); C3017(1.49); C3110(1.03); C4071(0.91)  LDD1042  [14]
 LDCM0445  CL54 HEK-293T C3008(1.64); C3017(1.64); C3110(0.77); C4071(1.15)  LDD1043  [14]
 LDCM0446  CL55 HEK-293T C3008(0.84); C3017(0.84); C3110(1.01); C4071(0.76)  LDD1044  [14]
 LDCM0447  CL56 HEK-293T C3008(0.95); C3017(0.95); C3110(1.00); C4071(0.86)  LDD1045  [14]
 LDCM0448  CL57 HEK-293T C3008(1.23); C3017(1.23); C3110(1.00); C4071(1.00)  LDD1046  [14]
 LDCM0449  CL58 HEK-293T C3008(0.76); C3017(0.76); C3110(1.11); C4071(1.12)  LDD1047  [14]
 LDCM0450  CL59 HEK-293T C3008(1.06); C3017(1.06); C3110(0.96); C4071(0.77)  LDD1048  [14]
 LDCM0451  CL6 HEK-293T C317(0.35); C4494(1.72)  LDD1049  [14]
 LDCM0452  CL60 HEK-293T C3008(1.24); C3017(1.24); C3110(1.26); C4071(1.19)  LDD1050  [14]
 LDCM0453  CL61 HEK-293T C3008(0.95); C3017(0.95); C317(0.47); C4494(1.15)  LDD1051  [14]
 LDCM0454  CL62 HEK-293T C3008(0.92); C3017(0.92); C317(0.33); C4494(1.09)  LDD1052  [14]
 LDCM0455  CL63 HEK-293T C3008(0.87); C3017(0.87); C317(0.25); C4494(1.17)  LDD1053  [14]
 LDCM0456  CL64 HEK-293T C3008(1.31); C3017(1.31); C317(0.36); C4494(1.08)  LDD1054  [14]
 LDCM0457  CL65 HEK-293T C3008(0.89); C3017(0.89); C317(0.47); C4494(1.01)  LDD1055  [14]
 LDCM0458  CL66 HEK-293T C3008(1.05); C3017(1.05); C317(0.30); C4494(1.00)  LDD1056  [14]
 LDCM0459  CL67 HEK-293T C3008(1.16); C3017(1.16); C317(0.34); C4494(0.88)  LDD1057  [14]
 LDCM0460  CL68 HEK-293T C3008(1.17); C3017(1.17); C317(0.31); C4494(1.00)  LDD1058  [14]
 LDCM0461  CL69 HEK-293T C3008(1.24); C3017(1.24); C317(0.39); C4494(1.03)  LDD1059  [14]
 LDCM0462  CL7 HEK-293T C317(0.21); C4494(1.84)  LDD1060  [14]
 LDCM0463  CL70 HEK-293T C3008(1.07); C3017(1.07); C317(0.46); C4494(1.01)  LDD1061  [14]
 LDCM0464  CL71 HEK-293T C3008(1.18); C3017(1.18); C317(0.33); C4494(1.18)  LDD1062  [14]
 LDCM0465  CL72 HEK-293T C3008(1.10); C3017(1.10); C317(0.45); C4494(0.95)  LDD1063  [14]
 LDCM0466  CL73 HEK-293T C3008(1.51); C3017(1.51); C317(0.34); C4494(1.14)  LDD1064  [14]
 LDCM0467  CL74 HEK-293T C3008(1.40); C3017(1.40); C317(0.21); C4494(1.18)  LDD1065  [14]
 LDCM0469  CL76 HEK-293T C3008(0.91); C3017(0.91); C3110(0.99); C4071(1.17)  LDD1067  [14]
 LDCM0470  CL77 HEK-293T C3008(1.10); C3017(1.10); C3110(0.79); C4071(1.24)  LDD1068  [14]
 LDCM0471  CL78 HEK-293T C3008(0.86); C3017(0.86); C3110(1.06); C4071(0.85)  LDD1069  [14]
 LDCM0472  CL79 HEK-293T C3008(0.96); C3017(0.96); C3110(0.92); C4071(0.94)  LDD1070  [14]
 LDCM0473  CL8 HEK-293T C317(0.12); C4494(0.85)  LDD1071  [14]
 LDCM0474  CL80 HEK-293T C3008(1.07); C3017(1.07); C3110(1.01); C4071(1.35)  LDD1072  [14]
 LDCM0475  CL81 HEK-293T C3008(1.00); C3017(1.00); C3110(1.08); C4071(1.09)  LDD1073  [14]
 LDCM0476  CL82 HEK-293T C3008(1.21); C3017(1.21); C3110(1.03); C4071(1.35)  LDD1074  [14]
 LDCM0477  CL83 HEK-293T C3008(1.33); C3017(1.33); C3110(1.00); C4071(1.04)  LDD1075  [14]
 LDCM0478  CL84 HEK-293T C3008(1.04); C3017(1.04); C3110(1.15); C4071(1.01)  LDD1076  [14]
 LDCM0479  CL85 HEK-293T C3008(0.93); C3017(0.93); C3110(0.95); C4071(0.97)  LDD1077  [14]
 LDCM0480  CL86 HEK-293T C3008(1.05); C3017(1.05); C3110(0.91); C4071(1.85)  LDD1078  [14]
 LDCM0481  CL87 HEK-293T C3008(1.35); C3017(1.35); C3110(1.19); C4071(1.06)  LDD1079  [14]
 LDCM0482  CL88 HEK-293T C3008(1.16); C3017(1.16); C3110(1.31); C4071(1.17)  LDD1080  [14]
 LDCM0483  CL89 HEK-293T C3008(1.02); C3017(1.02); C3110(1.07); C4071(1.26)  LDD1081  [14]
 LDCM0484  CL9 HEK-293T C317(0.28); C4494(0.85)  LDD1082  [14]
 LDCM0485  CL90 HEK-293T C3008(1.47); C3017(1.47); C3110(1.00); C4071(1.00)  LDD1083  [14]
 LDCM0486  CL91 HEK-293T C3110(0.98); C4494(0.82)  LDD1084  [14]
 LDCM0487  CL92 HEK-293T C3110(0.91); C4494(0.91)  LDD1085  [14]
 LDCM0488  CL93 HEK-293T C3110(0.84); C4494(1.04)  LDD1086  [14]
 LDCM0489  CL94 HEK-293T C3110(0.78); C4494(1.12)  LDD1087  [14]
 LDCM0490  CL95 HEK-293T C3110(0.76); C4494(1.60)  LDD1088  [14]
 LDCM0491  CL96 HEK-293T C3110(1.19); C4494(1.00)  LDD1089  [14]
 LDCM0492  CL97 HEK-293T C3110(0.79); C4494(0.85)  LDD1090  [14]
 LDCM0493  CL98 HEK-293T C3110(0.99); C4494(0.92)  LDD1091  [14]
 LDCM0494  CL99 HEK-293T C3110(0.93); C4494(0.91)  LDD1092  [14]
 LDCM0634  CY-0357 Hep-G2 C3295(3.14); C1136(0.26)  LDD2228  [20]
 LDCM0495  E2913 HEK-293T C3667(1.03); C317(1.04); C4494(0.98); C3110(1.07)  LDD1698  [32]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C317(4.29); C1136(1.59); C3110(1.47); C965(1.20)  LDD1702  [7]
 LDCM0572  Fragment10 MDA-MB-231 C3110(1.50); C992(2.09)  LDD1389  [33]
 LDCM0573  Fragment11 MDA-MB-231 C3110(1.67); C992(1.86); C4071(2.37)  LDD1391  [33]
 LDCM0574  Fragment12 MDA-MB-231 C3110(2.12); C992(1.76)  LDD1393  [33]
 LDCM0575  Fragment13 MDA-MB-231 C3110(0.74); C992(1.08); C4071(0.84)  LDD1395  [33]
 LDCM0576  Fragment14 MDA-MB-231 C3110(2.65); C992(1.68); C4071(3.13)  LDD1397  [33]
 LDCM0579  Fragment20 MDA-MB-231 C3110(1.75); C992(4.88); C4071(3.42)  LDD1402  [33]
 LDCM0580  Fragment21 MDA-MB-231 C3110(1.04); C992(1.03); C4071(2.01)  LDD1404  [33]
 LDCM0582  Fragment23 MDA-MB-231 C3110(1.25); C992(2.69)  LDD1408  [33]
 LDCM0584  Fragment25 MDA-MB-231 C3110(0.89); C4071(1.33)  LDD1411  [33]
 LDCM0578  Fragment27 MDA-MB-231 C3110(0.87); C992(1.15); C4071(0.93)  LDD1401  [33]
 LDCM0586  Fragment28 MDA-MB-231 C3110(0.92); C992(1.19)  LDD1415  [33]
 LDCM0587  Fragment29 MDA-MB-231 C3110(1.20); C992(1.20); C4071(1.08)  LDD1417  [33]
 LDCM0588  Fragment30 MDA-MB-231 C3110(0.82); C992(1.35)  LDD1419  [33]
 LDCM0589  Fragment31 MDA-MB-231 C3110(1.54); C992(1.15)  LDD1421  [33]
 LDCM0590  Fragment32 MDA-MB-231 C3110(2.28); C992(3.50)  LDD1423  [33]
 LDCM0468  Fragment33 HEK-293T C3008(1.44); C3017(1.44); C317(0.27); C4494(1.13)  LDD1066  [14]
 LDCM0593  Fragment35 MDA-MB-231 C4071(0.79)  LDD1429  [33]
 LDCM0594  Fragment36 MDA-MB-231 C3110(1.55)  LDD1431  [33]
 LDCM0596  Fragment38 MDA-MB-231 C3110(1.03)  LDD1433  [33]
 LDCM0566  Fragment4 MDA-MB-231 C3110(1.25); C992(1.86); C4071(2.83)  LDD1378  [33]
 LDCM0598  Fragment40 MDA-MB-231 C3110(0.94)  LDD1436  [33]
 LDCM0599  Fragment41 MDA-MB-231 C3110(1.28)  LDD1438  [33]
 LDCM0601  Fragment43 MDA-MB-231 C3110(1.88); C992(1.31); C4071(2.08)  LDD1441  [33]
 LDCM0603  Fragment45 MDA-MB-231 C3110(2.91)  LDD1444  [33]
 LDCM0604  Fragment46 MDA-MB-231 C3110(0.90); C992(1.58)  LDD1445  [33]
 LDCM0605  Fragment47 MDA-MB-231 C992(1.62)  LDD1446  [33]
 LDCM0606  Fragment48 MDA-MB-231 C992(0.84)  LDD1447  [33]
 LDCM0607  Fragment49 MDA-MB-231 C3110(2.79); C992(2.67)  LDD1448  [33]
 LDCM0608  Fragment50 MDA-MB-231 C3110(1.45)  LDD1449  [33]
 LDCM0427  Fragment51 HEK-293T C3008(1.25); C3017(1.25); C3110(1.24); C317(0.96)  LDD1025  [14]
 LDCM0610  Fragment52 MDA-MB-231 C3110(1.21); C4071(2.03)  LDD1452  [33]
 LDCM0611  Fragment53 MDA-MB-231 C3110(1.00); C992(1.07)  LDD1454  [33]
 LDCM0614  Fragment56 MDA-MB-231 C3110(0.95); C992(1.10)  LDD1458  [33]
 LDCM0568  Fragment6 MDA-MB-231 C3110(1.06); C992(1.56); C4071(1.78)  LDD1382  [33]
 LDCM0569  Fragment7 MDA-MB-231 C4071(2.38)  LDD1383  [33]
 LDCM0570  Fragment8 MDA-MB-231 C3110(1.38); C992(1.77)  LDD1385  [33]
 LDCM0571  Fragment9 MDA-MB-231 C3110(0.99); C992(1.48); C4071(2.09)  LDD1387  [33]
 LDCM0116  HHS-0101 DM93 Y4615(0.69); Y396(0.80); Y4155(0.98)  LDD0264  [13]
 LDCM0117  HHS-0201 DM93 Y4615(0.49); Y4155(0.63); Y396(0.86)  LDD0265  [13]
 LDCM0118  HHS-0301 DM93 Y4615(0.43); Y4155(0.74); Y396(1.08)  LDD0266  [13]
 LDCM0119  HHS-0401 DM93 Y4155(0.49); Y4615(0.70); Y396(0.77)  LDD0267  [13]
 LDCM0120  HHS-0701 DM93 Y4615(0.52); Y4155(0.58); Y396(0.68)  LDD0268  [13]
 LDCM0107  IAA HeLa C545(0.00); H2781(0.00); H1737(0.00); H3971(0.00)  LDD0221  [25]
 LDCM0179  JZ128 PC-3 C3299(0.00); C3493(0.00)  LDD0462  [11]
 LDCM0022  KB02 HCT 116 C4245(7.70); C4254(7.70); C3008(4.88); C3017(4.88)  LDD0080  [14]
 LDCM0023  KB03 HCT 116 C4245(19.78); C4254(19.78); C3008(18.36); C3017(18.36)  LDD0081  [14]
 LDCM0024  KB05 HCT 116 C4245(10.29); C4254(10.29); C3008(7.07); C3017(7.07)  LDD0082  [14]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C3295(1.01); C3110(0.79); C4494(1.08); C530(0.99)  LDD2102  [7]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C3295(0.69); C1156(0.74); C4454(0.60); C4574(0.89)  LDD2121  [7]
 LDCM0109  NEM HeLa H2748(0.00); H2781(0.00); H2996(0.00); C545(0.00)  LDD0223  [25]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C3295(0.67); C3299(0.96); C1136(0.63); C1156(0.40)  LDD2089  [7]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C3295(1.14); C1136(1.03); C1156(1.06); C4574(1.05)  LDD2090  [7]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C3295(1.09); C1156(1.36); C4574(0.81); C3110(1.01)  LDD2092  [7]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C3295(1.04); C1136(1.11); C1156(0.95); C4454(1.23)  LDD2093  [7]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C3295(1.10); C1156(2.84); C4574(1.18); C965(1.26)  LDD2094  [7]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C1156(0.24); C3110(0.95)  LDD2096  [7]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C1136(0.91); C1156(0.45); C4574(0.87); C3110(0.50)  LDD2097  [7]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C3295(0.91); C1136(0.71); C1156(1.13); C4574(0.88)  LDD2098  [7]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C3295(1.27); C3299(2.58); C1136(1.74); C1156(0.59)  LDD2099  [7]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C3295(0.54); C3299(0.32); C1156(0.23); C4574(1.06)  LDD2100  [7]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C1136(0.60); C4574(1.69); C3110(1.04); C530(0.47)  LDD2101  [7]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C3295(0.53); C1156(0.21); C3110(0.74); C965(0.84)  LDD2104  [7]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C1136(1.93); C1156(3.14); C4574(1.27); C4494(1.46)  LDD2105  [7]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C1136(0.29); C4574(0.77); C3110(0.57); C965(0.49)  LDD2106  [7]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C3295(1.46); C1136(1.50); C4454(1.48); C4574(1.24)  LDD2107  [7]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C3295(0.50); C1136(0.13); C1156(0.31); C4454(0.63)  LDD2108  [7]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C3295(0.65); C3299(1.05); C1136(0.76); C1156(0.37)  LDD2109  [7]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C3295(0.52); C1156(0.29); C4454(0.43); C3110(0.83)  LDD2110  [7]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C3295(0.94); C3299(1.75); C1156(0.85); C4574(1.46)  LDD2111  [7]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C3295(0.64); C1156(0.24); C4454(0.52); C3110(0.94)  LDD2114  [7]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C3295(0.88); C1156(0.69); C3110(0.55); C530(0.48)  LDD2115  [7]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C3295(1.14); C1156(0.53); C3110(1.84)  LDD2116  [7]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C3295(0.97); C1156(0.51); C3110(1.19); C965(3.70)  LDD2118  [7]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C3295(2.39); C1136(1.89); C4574(2.90); C3110(2.49)  LDD2119  [7]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C3295(0.78); C1156(0.92); C4574(1.00); C3110(0.81)  LDD2120  [7]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C3295(0.98); C1156(0.30); C3110(0.78); C965(2.29)  LDD2122  [7]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C3295(1.08); C3299(1.68); C1136(1.41); C4454(1.04)  LDD2123  [7]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C3295(0.97); C1156(0.33); C3110(0.93); C965(2.17)  LDD2124  [7]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C3295(0.92); C3299(1.37); C1136(1.13); C1156(0.63)  LDD2125  [7]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C3295(0.79); C1156(0.30); C3110(0.95); C965(2.29)  LDD2126  [7]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C3295(1.04); C1136(1.31); C4574(1.11); C3110(1.09)  LDD2127  [7]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C3295(0.93); C1156(0.55); C4454(1.01); C4574(1.48)  LDD2128  [7]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C3295(1.48); C3299(1.72); C1136(1.07); C4574(2.03)  LDD2129  [7]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C3295(0.61); C1136(0.38); C4574(0.79); C530(0.48)  LDD2133  [7]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C3299(0.49); C3110(0.46); C4494(0.42); C530(0.48)  LDD2134  [7]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C3295(1.44); C3299(1.63); C1136(1.52); C4574(1.77)  LDD2135  [7]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C3295(1.45); C3299(1.95); C1136(2.11); C4454(1.27)  LDD2136  [7]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C3295(0.98); C1136(1.49); C1156(0.73); C4574(1.43)  LDD2137  [7]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C3110(2.55); C4574(2.01); C3295(1.97); C4494(1.48)  LDD1700  [7]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C3295(0.85); C3299(1.04); C1156(0.57); C4454(0.84)  LDD2140  [7]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C3295(0.67); C3299(1.06); C1156(0.40); C4454(0.61)  LDD2141  [7]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C3295(0.96); C1156(0.90); C4574(0.96); C3110(0.70)  LDD2143  [7]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C3295(2.88); C3299(2.22); C1136(2.48); C3110(1.85)  LDD2144  [7]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C3295(7.30); C1156(1.88); C3110(7.53); C4494(8.95)  LDD2145  [7]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C3295(1.00); C1136(0.79); C4574(1.39); C3110(1.15)  LDD2146  [7]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C3295(2.09); C1156(2.64); C4454(1.38); C4574(2.21)  LDD2147  [7]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C3295(0.54); C4574(0.66); C3110(0.51); C530(0.43)  LDD2148  [7]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C3295(1.00); C1156(0.40); C3110(1.26)  LDD2149  [7]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C3295(0.41); C3299(0.52); C1156(0.13); C4454(0.32)  LDD2150  [7]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C1156(0.33); C3110(1.64)  LDD2151  [7]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C3295(1.94); C1136(2.30); C4494(1.97); C530(1.90)  LDD2153  [7]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Integrin beta-4 (ITGB4) Integrin beta chain family P16144
Kelch-like ECH-associated protein 1 (KEAP1) KEAP1 family Q14145
RNA-binding protein FUS (FUS) RRM TET family P35637

References

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3 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
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Mass spectrometry data entry: PXD028270
7 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD042888
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Mass spectrometry data entry: PXD044625
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15 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
16 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
17 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
18 Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer. J Proteome Res. 2018 Jan 5;17(1):63-75. doi: 10.1021/acs.jproteome.7b00329. Epub 2017 Nov 22.
Mass spectrometry data entry: PXD006095 , PXD006096
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Mass spectrometry data entry: PXD029255
20 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
21 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD039931
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Mass spectrometry data entry: PXD033004
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Mass spectrometry data entry: PXD038010
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Mass spectrometry data entry: PXD044402
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