Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | FFF probe12 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:200uM; negative probe:200uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
SILAC
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Chronic myeloid leukemia [ICD-11:2A20] | |||||
| Model Name | Human chronic myeloid leukemia cells (K562) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP08476 | 5'-3' exonuclease PLD3 (PLD3) | 20.0 | ||||
| LDTP02223 | Cathepsin B (CTSB) | 20.0 | ||||
| LDTP04572 | Dipeptidyl peptidase 1 (CTSC) | 20.0 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 20.0 | ||||
| LDTP11215 | Plasma alpha-L-fucosidase (FUCA2) | 20.0 | ||||
| LDTP05548 | Protein-glutamine gamma-glutamyltransferase E (TGM3) | 20.0 | ||||
| LDTP00886 | Nardilysin (NRDC) | 12.8 | ||||
| LDTP02198 | Cathepsin D (CTSD) | 12.4 | ||||
| LDTP00758 | Thioredoxin-like protein 1 (TXNL1) | 8.9 | ||||
| LDTP03419 | Proteasome subunit beta type-5 (PSMB5) | 7.3 | ||||
| LDTP03560 | Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) | 6.1 | ||||
| LDTP06384 | Ribosomal protein S6 kinase alpha-1 (RPS6KA1) | 6.1 | ||||
| LDTP04471 | Ribosomal protein S6 kinase alpha-3 (RPS6KA3) | 5.7 | ||||
| LDTP01687 | Apoptosis-inducing factor 1, mitochondrial (AIFM1) | 5.5 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02815 | Desmoplakin (DSP) | 20.0 | ||||
| LDTP02215 | Prosaposin (PSAP) | 20.0 | ||||
| LDTP10885 | Sortilin (SORT1) | 20.0 | ||||
| LDTP01969 | Transferrin receptor protein 1 (TFRC) | 20.0 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP05567 | Desmocollin-1 (DSC1) | 20.0 | ||||
| LDTP05353 | Desmoglein-1 (DSG1) | 20.0 | ||||
| LDTP02756 | Junction plakoglobin (JUP) | 20.0 | ||||
| LDTP05375 | Nucleobindin-1 (NUCB1) | 20.0 | ||||
| LDTP04684 | Nucleosome assembly protein 1-like 1 (NAP1L1) | 20.0 | ||||
| LDTP10965 | Nucleosome assembly protein 1-like 4 (NAP1L4) | 20.0 | ||||
| LDTP06330 | Plectin (PLEC) | 20.0 | ||||
| LDTP03493 | Serpin B3 (SERPINB3) | 20.0 | ||||
| LDTP02053 | Heat shock protein beta-1 (HSPB1) | 11.2 | ||||
| LDTP00887 | Calumenin (CALU) | 10.8 | ||||
| LDTP06097 | Reticulocalbin-2 (RCN2) | 9.6 | ||||