Details of the Probe-central Interaction Altas
General Information of Experiment
Probe Name | DA-2 | Probe Info | ||||
---|---|---|---|---|---|---|
Probe concentration | 10 uM | |||||
Criteria | Other data | |||||
In Vivo Experiment Model | Model Type |
|
Living cell | |||
Derived Tissue |
|
Peripheral blood | ||||
Disease Model | Chronic myeloid leukemia [ICD-11:2A20] | |||||
Model Name | Human chronic myeloid leukemia cells (K562) | |||||
Interaction Altas of This Experiment [1]
Enzyme
Target ID | Target Name | |||||
---|---|---|---|---|---|---|
LDTP10404 | 2-oxoadipate dehydrogenase complex component E1 (DHTKD1) | |||||
LDTP10869 | 26S proteasome non-ATPase regulatory subunit 1 (PSMD1) | |||||
LDTP05782 | 26S proteasome non-ATPase regulatory subunit 2 (PSMD2) | |||||
LDTP10954 | 3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) | |||||
LDTP02522 | 60 kDa heat shock protein, mitochondrial (HSPD1) | |||||
LDTP05069 | Actin, alpha cardiac muscle 1 (ACTC1) | |||||
LDTP05073 | Actin, alpha skeletal muscle (ACTA1) | |||||
LDTP04689 | Adenosine kinase (ADK) | |||||
LDTP04262 | Alanine--tRNA ligase, cytoplasmic (AARS1) | |||||
LDTP15371 | Aldehyde dehydrogenase family 16 member A1 (ALDH16A1) | |||||
LDTP02765 | Aldo-keto reductase family 1 member B1 (AKR1B1) | |||||
LDTP05436 | Aldo-keto reductase family 1 member C1 (AKR1C1) | |||||
LDTP02100 | Alkaline phosphatase, placental type (ALPP) | |||||
LDTP15993 | Aminopeptidase B (RNPEP) | |||||
LDTP04601 | Arginine--tRNA ligase, cytoplasmic (RARS1) | |||||
LDTP00866 | Asparagine--tRNA ligase, cytoplasmic (NARS1) | |||||
LDTP01783 | Aspartate aminotransferase, mitochondrial (GOT2) | |||||
LDTP04561 | ATP-citrate synthase (ACLY) | |||||
LDTP02925 | ATP-dependent 6-phosphofructokinase, liver type (PFKL) | |||||
LDTP05314 | ATP-dependent 6-phosphofructokinase, platelet type (PFKP) | |||||
LDTP05550 | ATP-dependent RNA helicase A (DHX9) | |||||
LDTP09766 | ATP-dependent RNA helicase DDX1 (DDX1) | |||||
LDTP00314 | ATP-dependent RNA helicase DDX3X (DDX3X) | |||||
LDTP00664 | ATP-dependent RNA helicase DDX3Y (DDX3Y) | |||||
LDTP00684 | ATP-dependent RNA helicase DHX15 (DHX15) | |||||
LDTP12681 | ATPase family AAA domain-containing protein 3A (ATAD3A) | |||||
LDTP01564 | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2) | |||||
LDTP02222 | Bifunctional glutamate/proline--tRNA ligase (EPRS1) | |||||
LDTP02580 | C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) | |||||
LDTP02911 | Calpain-2 catalytic subunit (CAPN2) | |||||
LDTP02909 | cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) | |||||
LDTP02831 | Carbonyl reductase [NADPH] 1 (CBR1) | |||||
LDTP12048 | Complex I assembly factor ACAD9, mitochondrial (ACAD9) | |||||
LDTP02616 | Creatine kinase B-type (CKB) | |||||
LDTP02922 | CTP synthase 1 (CTPS1) | |||||
LDTP05949 | Cullin-4A (CUL4A) | |||||
LDTP05950 | Cullin-4B (CUL4B) | |||||
LDTP08296 | Cullin-associated NEDD8-dissociated protein 1 (CAND1) | |||||
LDTP04124 | Cytosolic phospholipase A2 (PLA2G4A) | |||||
LDTP04646 | Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) | |||||
LDTP02497 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT) | |||||
LDTP03316 | DNA replication licensing factor MCM3 (MCM3) | |||||
LDTP03680 | DNA replication licensing factor MCM4 (MCM4) | |||||
LDTP03681 | DNA replication licensing factor MCM5 (MCM5) | |||||
LDTP06150 | DNA replication licensing factor MCM6 (MCM6) | |||||
LDTP03682 | DNA replication licensing factor MCM7 (MCM7) | |||||
LDTP05136 | DNA-dependent protein kinase catalytic subunit (PRKDC) | |||||
LDTP03564 | DNA-directed RNA polymerase II subunit RPB2 (POLR2B) | |||||
LDTP06098 | E3 ubiquitin/ISG15 ligase TRIM25 (TRIM25) | |||||
LDTP02694 | Electron transfer flavoprotein subunit alpha, mitochondrial (ETFA) | |||||
LDTP04251 | Elongation factor Tu, mitochondrial (TUFM) | |||||
LDTP03518 | Enoyl-CoA hydratase, mitochondrial (ECHS1) | |||||
LDTP04243 | Fatty acid synthase (FASN) | |||||
LDTP02386 | Fructose-bisphosphate aldolase C (ALDOC) | |||||
LDTP03103 | Glutathione S-transferase Mu 3 (GSTM3) | |||||
LDTP02161 | Glycogen phosphorylase, liver form (PYGL) | |||||
LDTP01782 | Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) | |||||
LDTP02611 | Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) | |||||
LDTP03003 | Interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2) | |||||
LDTP03947 | Isoleucine--tRNA ligase, cytoplasmic (IARS1) | |||||
LDTP12588 | Isoleucine--tRNA ligase, mitochondrial (IARS2) | |||||
LDTP13056 | Leucine--tRNA ligase, cytoplasmic (LARS1) | |||||
LDTP03817 | Lon protease homolog, mitochondrial (LONP1) | |||||
LDTP06294 | Lysine--tRNA ligase (KARS1) | |||||
LDTP03907 | Malate dehydrogenase, cytoplasmic (MDH1) | |||||
LDTP05971 | Mannosyl-oligosaccharide glucosidase (MOGS) | |||||
LDTP02565 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) | |||||
LDTP12915 | Methionine adenosyltransferase 2 subunit beta (MAT2B) | |||||
LDTP05632 | Mitochondrial-processing peptidase subunit alpha (PMPCA) | |||||
LDTP06631 | NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial (NDUFA9) | |||||
LDTP06192 | Neutral alpha-glucosidase AB (GANAB) | |||||
LDTP04051 | Nicotinamide phosphoribosyltransferase (NAMPT) | |||||
LDTP02796 | Nucleoside diphosphate kinase A (NME1) | |||||
LDTP12610 | Obg-like ATPase 1 (OLA1) | |||||
LDTP10878 | Parkinson disease protein 7 (PARK7) | |||||
LDTP03216 | Peptidyl-prolyl cis-trans isomerase B (PPIB) | |||||
LDTP04440 | Peroxisomal multifunctional enzyme type 2 (HSD17B4) | |||||
LDTP03818 | Phosphoglucomutase-1 (PGM1) | |||||
LDTP01787 | Phosphoglycerate kinase 1 (PGK1) | |||||
LDTP02186 | Phosphoglycerate kinase 2 (PGK2) | |||||
LDTP02375 | Poly [ADP-ribose] polymerase 1 (PARP1) | |||||
LDTP09899 | Probable ATP-dependent RNA helicase DDX17 (DDX17) | |||||
LDTP02924 | Probable ATP-dependent RNA helicase DDX5 (DDX5) | |||||
LDTP16026 | Probable cysteine--tRNA ligase, mitochondrial (CARS2) | |||||
LDTP13750 | Proliferation-associated protein 2G4 (PA2G4) | |||||
LDTP03331 | Proteasome subunit alpha type-2 (PSMA2) | |||||
LDTP03413 | Proteasome subunit alpha type-5 (PSMA5) | |||||
LDTP00449 | Proteasome subunit alpha type-7 (PSMA7) | |||||
LDTP03521 | Protein disulfide-isomerase A3 (PDIA3) | |||||
LDTP06314 | Protein disulfide-isomerase A6 (PDIA6) | |||||
LDTP04712 | Puromycin-sensitive aminopeptidase (NPEPPS) | |||||
LDTP00343 | Pyridoxal kinase (PDXK) | |||||
LDTP03644 | Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) | |||||
LDTP02733 | Pyruvate kinase PKM (PKM) | |||||
LDTP04895 | Ras-related protein Rab-10 (RAB10) | |||||
LDTP04399 | Ras-related protein Rab-7a (RAB7A) | |||||
LDTP04910 | Ras-related protein Rap-1b (RAP1B) | |||||
LDTP04882 | Ribose-phosphate pyrophosphokinase 1 (PRPS1) | |||||
LDTP02592 | Ribose-phosphate pyrophosphokinase 2 (PRPS2) | |||||
LDTP02860 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) | |||||
LDTP03689 | Serine hydroxymethyltransferase, mitochondrial (SHMT2) | |||||
LDTP00299 | Serine/threonine-protein kinase 25 (STK25) | |||||
LDTP03819 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC) | |||||
LDTP07929 | Staphylococcal nuclease domain-containing protein 1 (SND1) | |||||
LDTP03572 | Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) | |||||
LDTP06658 | Thioredoxin reductase 1, cytoplasmic (TXNRD1) | |||||
LDTP03365 | Threonine--tRNA ligase 1, cytoplasmic (TARS1) | |||||
LDTP02055 | Thymidylate synthase (TYMS) | |||||
LDTP03912 | Trifunctional enzyme subunit alpha, mitochondrial (HADHA) | |||||
LDTP03156 | Trifunctional purine biosynthetic protein adenosine-3 (GART) | |||||
LDTP04851 | Triosephosphate isomerase (TPI1) | |||||
LDTP07907 | Tubulin alpha-1A chain (TUBA1A) | |||||
LDTP06639 | Tyrosine-protein phosphatase non-receptor type 21 (PTPN21) | |||||
LDTP01283 | U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) | |||||
LDTP13927 | Ubiquitin-conjugating enzyme E2 D4 (UBE2D4) | |||||
LDTP12851 | UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1) | |||||
LDTP03366 | Valine--tRNA ligase (VARS1) | |||||
LDTP04289 | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) | |||||
LDTP12867 | Very-long-chain enoyl-CoA reductase (TECR) | |||||
LDTP04096 | Vesicle-fusing ATPase (NSF) | |||||
LDTP02642 | X-ray repair cross-complementing protein 5 (XRCC5) |
Transporter and channel
Target ID | Target Name | |||||
---|---|---|---|---|---|---|
LDTP04969 | 14-3-3 protein epsilon (YWHAE) | |||||
LDTP04953 | 14-3-3 protein gamma (YWHAG) | |||||
LDTP02609 | ADP/ATP translocase 3 (SLC25A6) | |||||
LDTP02247 | Annexin A6 (ANXA6) | |||||
LDTP05625 | AP-1 complex subunit beta-1 (AP1B1) | |||||
LDTP05038 | AP-2 complex subunit beta (AP2B1) | |||||
LDTP03327 | ATP synthase subunit alpha, mitochondrial (ATP5F1A) | |||||
LDTP03405 | Calnexin (CANX) | |||||
LDTP00244 | Chloride intracellular channel protein 1 (CLIC1) | |||||
LDTP04578 | Clathrin heavy chain 2 (CLTCL1) | |||||
LDTP02057 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) | |||||
LDTP01301 | Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12) | |||||
LDTP00501 | Exportin-1 (XPO1) | |||||
LDTP04662 | Exportin-2 (CSE1L) | |||||
LDTP01197 | Filamin-B (FLNB) | |||||
LDTP05017 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) | |||||
LDTP06242 | Importin subunit beta-1 (KPNB1) | |||||
LDTP00266 | Importin-5 (IPO5) | |||||
LDTP10663 | Importin-9 (IPO9) | |||||
LDTP12916 | Myoferlin (MYOF) | |||||
LDTP01295 | Nuclear pore complex protein Nup155 (NUP155) | |||||
LDTP08769 | Nuclear pore complex protein Nup93 (NUP93) | |||||
LDTP03717 | Prohibitin 1 (PHB1) | |||||
LDTP04707 | Protein SEC13 homolog (SEC13) | |||||
LDTP03837 | Signal recognition particle 14 kDa protein (SRP14) | |||||
LDTP05057 | Small ribosomal subunit protein RACK1 (RACK1) | |||||
LDTP14636 | Solute carrier family 25 member 16 (SLC25A16) | |||||
LDTP05273 | Spectrin beta chain, non-erythrocytic 1 (SPTBN1) | |||||
LDTP01969 | Transferrin receptor protein 1 (TFRC) | |||||
LDTP00196 | Unconventional myosin-Ic (MYO1C) | |||||
LDTP10741 | Vacuolar protein sorting-associated protein 35 (VPS35) | |||||
LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) |
Transcription factor
Target ID | Target Name | |||||
---|---|---|---|---|---|---|
LDTP12964 | Forkhead box protein J2 (FOXJ2) | |||||
LDTP06341 | Non-POU domain-containing octamer-binding protein (NONO) | |||||
LDTP03903 | Signal transducer and activator of transcription 3 (STAT3) | |||||
LDTP03212 | Splicing factor, proline- and glutamine-rich (SFPQ) |
Other
Target ID | Target Name | |||||
---|---|---|---|---|---|---|
LDTP03617 | 14-3-3 protein beta/alpha (YWHAB) | |||||
LDTP04902 | Actin-related protein 3 (ACTR3) | |||||
LDTP16166 | Actin-related protein 3B (ACTR3B) | |||||
LDTP02631 | Alpha-actinin-1 (ACTN1) | |||||
LDTP05542 | Alpha-actinin-3 (ACTN3) | |||||
LDTP02620 | Annexin A3 (ANXA3) | |||||
LDTP02354 | Annexin A4 (ANXA4) | |||||
LDTP05719 | Cleavage stimulation factor subunit 3 (CSTF3) | |||||
LDTP04571 | Coatomer subunit alpha (COPA) | |||||
LDTP04570 | Coatomer subunit beta (COPB1) | |||||
LDTP06543 | DNA damage-binding protein 1 (DDB1) | |||||
LDTP04028 | DNA mismatch repair protein Msh2 (MSH2) | |||||
LDTP04518 | DNA mismatch repair protein Msh6 (MSH6) | |||||
LDTP06450 | ELAV-like protein 1 (ELAVL1) | |||||
LDTP03283 | Elongation factor 1-beta (EEF1B2) | |||||
LDTP03499 | Elongation factor 1-delta (EEF1D) | |||||
LDTP03678 | ER lumen protein-retaining receptor 2 (KDELR2) | |||||
LDTP13813 | Eukaryotic translation initiation factor 3 subunit L (EIF3L) | |||||
LDTP04743 | Eukaryotic translation initiation factor 6 (EIF6) | |||||
LDTP02779 | Ezrin (EZR) | |||||
LDTP04544 | F-actin-capping protein subunit alpha-1 (CAPZA1) | |||||
LDTP10078 | Far upstream element-binding protein 1 (FUBP1) | |||||
LDTP09938 | Far upstream element-binding protein 2 (KHSRP) | |||||
LDTP06598 | Fascin (FSCN1) | |||||
LDTP10015 | GPI transamidase component PIG-T (PIGT) | |||||
LDTP03694 | Heat shock 70 kDa protein 1-like (HSPA1L) | |||||
LDTP04514 | Heterogeneous nuclear ribonucleoprotein F (HNRNPF) | |||||
LDTP03615 | Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) | |||||
LDTP02750 | Heterogeneous nuclear ribonucleoprotein L (HNRNPL) | |||||
LDTP04500 | Heterogeneous nuclear ribonucleoprotein M (HNRNPM) | |||||
LDTP00991 | Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) | |||||
LDTP00756 | Heterogeneous nuclear ribonucleoprotein R (HNRNPR) | |||||
LDTP17065 | Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) | |||||
LDTP03182 | Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) | |||||
LDTP02060 | Histone H2A type 1-B/E (H2AC4; H2AC8) | |||||
LDTP06628 | Histone H2B type 2-E (H2BC21) | |||||
LDTP00272 | Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) | |||||
LDTP05688 | Interleukin enhancer-binding factor 2 (ILF2) | |||||
LDTP05689 | Interleukin enhancer-binding factor 3 (ILF3) | |||||
LDTP06681 | Inverted formin-2 (INF2) | |||||
LDTP02756 | Junction plakoglobin (JUP) | |||||
LDTP02305 | Keratin, type II cytoskeletal 7 (KRT7) | |||||
LDTP03265 | Laminin subunit alpha-2 (LAMA2) | |||||
LDTP04094 | Large proline-rich protein BAG6 (BAG6) | |||||
LDTP04389 | Large ribosomal subunit protein eL14 (RPL14) | |||||
LDTP05196 | Large ribosomal subunit protein eL19 (RPL19) | |||||
LDTP05360 | Large ribosomal subunit protein eL20 (RPL18A) | |||||
LDTP04107 | Large ribosomal subunit protein eL21 (RPL21) | |||||
LDTP05378 | Large ribosomal subunit protein eL6 (RPL6) | |||||
LDTP02109 | Large ribosomal subunit protein uL10 (RPLP0) | |||||
LDTP03517 | Large ribosomal subunit protein uL11 (RPL12) | |||||
LDTP04106 | Large ribosomal subunit protein uL18 (RPL5) | |||||
LDTP05027 | Large ribosomal subunit protein uL2 (RPL8) | |||||
LDTP04027 | Matrin-3 (MATR3) | |||||
LDTP02164 | Nucleophosmin (NPM1) | |||||
LDTP03520 | Phosphatidylethanolamine-binding protein 1 (PEBP1) | |||||
LDTP06330 | Plectin (PLEC) | |||||
LDTP02595 | Polyadenylate-binding protein 1 (PABPC1) | |||||
LDTP03364 | Polypyrimidine tract-binding protein 1 (PTBP1) | |||||
LDTP01932 | Prelamin-A/C (LMNA) | |||||
LDTP09580 | Programmed cell death 6-interacting protein (PDCD6IP) | |||||
LDTP02596 | Proliferating cell nuclear antigen (PCNA) | |||||
LDTP14956 | Putative heat shock protein HSP 90-beta 2 (HSP90AB2P) | |||||
LDTP13956 | Putative RNA-binding protein Luc7-like 2 (LUC7L2) | |||||
LDTP04355 | Rab GDP dissociation inhibitor beta (GDI2) | |||||
LDTP04117 | Ras GTPase-activating-like protein IQGAP1 (IQGAP1) | |||||
LDTP03775 | RNA-binding protein FUS (FUS) | |||||
LDTP04395 | RNA-binding protein FXR1 (FXR1) | |||||
LDTP13991 | Serine-threonine kinase receptor-associated protein (STRAP) | |||||
LDTP06583 | Serine/arginine-rich splicing factor 7 (SRSF7) | |||||
LDTP03479 | SHC-transforming protein 1 (SHC1) | |||||
LDTP04913 | Small ribosomal subunit protein eS1 (RPS3A) | |||||
LDTP04997 | Small ribosomal subunit protein eS4, X isoform (RPS4X) | |||||
LDTP05002 | Small ribosomal subunit protein eS6 (RPS6) | |||||
LDTP04964 | Small ribosomal subunit protein eS8 (RPS8) | |||||
LDTP04975 | Small ribosomal subunit protein uS17 (RPS11) | |||||
LDTP02809 | Small ribosomal subunit protein uS5 (RPS2) | |||||
LDTP05985 | Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) | |||||
LDTP01251 | Splicing factor 3B subunit 1 (SF3B1) | |||||
LDTP06376 | Splicing factor 3B subunit 3 (SF3B3) | |||||
LDTP09821 | Stalled ribosome sensor GCN1 (GCN1) | |||||
LDTP03619 | Stress-induced-phosphoprotein 1 (STIP1) | |||||
LDTP11643 | Superkiller complex protein 8 (SKIC8) | |||||
LDTP02934 | T-complex protein 1 subunit alpha (TCP1) | |||||
LDTP05113 | T-complex protein 1 subunit beta (CCT2) | |||||
LDTP04201 | T-complex protein 1 subunit epsilon (CCT5) | |||||
LDTP03888 | T-complex protein 1 subunit zeta (CCT6A) | |||||
LDTP11277 | Tubulin beta-2B chain (TUBB2B) | |||||
LDTP02037 | Tubulin beta-4A chain (TUBB4A) | |||||
LDTP11233 | Tubulin beta-6 chain (TUBB6) | |||||
LDTP05650 | Twinfilin-1 (TWF1) | |||||
LDTP05033 | Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) | |||||
LDTP01206 | Vesicle-trafficking protein SEC22b (SEC22B) | |||||
LDTP02297 | Vimentin (VIM) | |||||
LDTP05641 | WASH complex subunit 5 (WASHC5) |