Details of the Target
General Information of Target
Target ID | LDTP05641 | |||||
---|---|---|---|---|---|---|
Target Name | WASH complex subunit 5 (WASHC5) | |||||
Gene Name | WASHC5 | |||||
Gene ID | 9897 | |||||
Synonyms |
KIAA0196; WASH complex subunit 5; Strumpellin; WASH complex subunit strumpellin |
|||||
3D Structure | ||||||
Sequence |
MLDFLAENNLCGQAILRIVSCGNAIIAELLRLSEFIPAVFRLKDRADQQKYGDIIFDFSY
FKGPELWESKLDAKPELQDLDEEFRENNIEIVTRFYLAFQSVHKYIVDLNRYLDDLNEGV YIQQTLETVLLNEDGKQLLCEALYLYGVMLLVIDQKIEGEVRERMLVSYYRYSAARSSAD SNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQVSA YPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITVNL VDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDNIP KLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTAQF EFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFREIS KQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTINI KEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLLRI NQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDKDK LRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRVAF ALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRIINY NVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTCHI DQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKIIL RDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILRQQ IANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLEAA GIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVLGL LTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKLPR RVAEAHVPNFIFDEFRTVL |
|||||
Target Bioclass |
Other
|
|||||
Family |
Strumpellin family
|
|||||
Subcellular location |
Cytoplasm, cytosol
|
|||||
Function |
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. May be involved in axonal outgrowth. Involved in cellular localization of ADRB2. Involved in cellular trafficking of BLOC-1 complex cargos such as ATP7A and VAMP7.
|
|||||
Uniprot ID | ||||||
Ensemble ID | ||||||
HGNC ID |
Probe(s) Labeling This Target
ABPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
---|---|---|---|---|---|
Probe 1 Probe Info |
![]() |
Y195(208.43) | LDD3495 | [1] | |
BTD Probe Info |
![]() |
C1064(2.93) | LDD2119 | [2] | |
HHS-465 Probe Info |
![]() |
Y801(3.57) | LDD2237 | [3] | |
Acrolein Probe Info |
![]() |
N.A. | LDD0224 | [4] | |
DBIA Probe Info |
![]() |
C1064(2.12); C969(3.68); C385(9.24) | LDD0080 | [5] | |
ATP probe Probe Info |
![]() |
K974(0.00); K985(0.00) | LDD0199 | [6] | |
4-Iodoacetamidophenylacetylene Probe Info |
![]() |
C786(0.00); C21(0.00); C1064(0.00); C838(0.00) | LDD0038 | [7] | |
IA-alkyne Probe Info |
![]() |
C21(0.00); C838(0.00); C1064(0.00); C969(0.00) | LDD0036 | [7] | |
Lodoacetamide azide Probe Info |
![]() |
C786(0.00); C21(0.00); C838(0.00); C1064(0.00) | LDD0037 | [7] | |
IPM Probe Info |
![]() |
C21(0.00); C385(0.00); C187(0.00) | LDD2156 | [8] | |
TFBX Probe Info |
![]() |
C187(0.00); C365(0.00); C1064(0.00); C21(0.00) | LDD0148 | [9] | |
YN-1 Probe Info |
![]() |
N.A. | LDD0446 | [10] | |
NAIA_5 Probe Info |
![]() |
C21(0.00); C838(0.00); C187(0.00) | LDD2223 | [11] |
PAL-AfBPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
---|---|---|---|---|---|
C112 Probe Info |
![]() |
17.75 | LDD1799 | [12] | |
C193 Probe Info |
![]() |
6.15 | LDD1869 | [12] | |
C201 Probe Info |
![]() |
37.01 | LDD1877 | [12] | |
C216 Probe Info |
![]() |
6.92 | LDD1890 | [12] | |
C238 Probe Info |
![]() |
11.08 | LDD1911 | [12] | |
C265 Probe Info |
![]() |
13.55 | LDD1936 | [12] | |
C403 Probe Info |
![]() |
17.75 | LDD2061 | [12] | |
DA-2 Probe Info |
![]() |
N.A. | LDD0071 | [13] |
Competitor(s) Related to This Target
Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
---|---|---|---|---|---|
LDCM0214 | AC1 | HCT 116 | C969(0.83); C1064(1.02); C187(0.91); C21(1.39) | LDD0531 | [5] |
LDCM0215 | AC10 | HCT 116 | C969(0.73); C1064(1.10); C187(0.81); C21(1.31) | LDD0532 | [5] |
LDCM0216 | AC100 | HCT 116 | C969(0.72); C21(0.87); C786(1.18) | LDD0533 | [5] |
LDCM0217 | AC101 | HCT 116 | C969(0.75); C21(0.96); C786(1.12) | LDD0534 | [5] |
LDCM0218 | AC102 | HCT 116 | C969(0.73); C21(0.97); C786(1.20) | LDD0535 | [5] |
LDCM0219 | AC103 | HCT 116 | C969(0.74); C21(1.09); C786(1.00) | LDD0536 | [5] |
LDCM0220 | AC104 | HCT 116 | C969(0.68); C21(1.16); C786(1.04) | LDD0537 | [5] |
LDCM0221 | AC105 | HCT 116 | C969(0.69); C21(1.10); C786(1.01) | LDD0538 | [5] |
LDCM0222 | AC106 | HCT 116 | C969(0.72); C21(0.88); C786(1.12) | LDD0539 | [5] |
LDCM0223 | AC107 | HCT 116 | C969(0.70); C21(1.11); C786(1.03) | LDD0540 | [5] |
LDCM0224 | AC108 | HCT 116 | C969(0.72); C21(0.88); C786(1.16) | LDD0541 | [5] |
LDCM0225 | AC109 | HCT 116 | C969(0.74); C21(0.88); C786(1.06) | LDD0542 | [5] |
LDCM0226 | AC11 | HCT 116 | C969(0.70); C1064(1.08); C187(0.71); C21(1.25) | LDD0543 | [5] |
LDCM0227 | AC110 | HCT 116 | C969(0.78); C21(0.92); C786(1.10) | LDD0544 | [5] |
LDCM0228 | AC111 | HCT 116 | C969(0.75); C21(0.81); C786(0.96) | LDD0545 | [5] |
LDCM0229 | AC112 | HCT 116 | C969(0.73); C21(0.89); C786(0.90) | LDD0546 | [5] |
LDCM0230 | AC113 | HCT 116 | C969(1.01); C1064(1.00); C21(1.06); C786(1.18) | LDD0547 | [5] |
LDCM0231 | AC114 | HCT 116 | C969(0.94); C1064(1.19); C21(1.35); C786(1.01) | LDD0548 | [5] |
LDCM0232 | AC115 | HCT 116 | C969(0.97); C1064(1.23); C21(1.72); C786(0.80) | LDD0549 | [5] |
LDCM0233 | AC116 | HCT 116 | C969(0.99); C1064(0.91); C21(1.62); C786(1.28) | LDD0550 | [5] |
LDCM0234 | AC117 | HCT 116 | C969(0.91); C1064(0.93); C21(1.27); C786(1.10) | LDD0551 | [5] |
LDCM0235 | AC118 | HCT 116 | C969(1.01); C1064(1.23); C21(1.25); C786(1.10) | LDD0552 | [5] |
LDCM0236 | AC119 | HCT 116 | C969(0.90); C1064(1.21); C21(1.34); C786(1.48) | LDD0553 | [5] |
LDCM0237 | AC12 | HCT 116 | C969(0.74); C1064(0.93); C187(0.75); C21(1.05) | LDD0554 | [5] |
LDCM0238 | AC120 | HCT 116 | C969(0.88); C1064(1.08); C21(1.54); C786(1.18) | LDD0555 | [5] |
LDCM0239 | AC121 | HCT 116 | C969(1.07); C1064(1.01); C21(1.05); C786(1.36) | LDD0556 | [5] |
LDCM0240 | AC122 | HCT 116 | C969(0.86); C1064(0.99); C21(1.24); C786(1.06) | LDD0557 | [5] |
LDCM0241 | AC123 | HCT 116 | C969(1.00); C1064(1.31); C21(1.15); C786(0.98) | LDD0558 | [5] |
LDCM0242 | AC124 | HCT 116 | C969(1.13); C1064(1.26); C21(1.14); C786(1.55) | LDD0559 | [5] |
LDCM0243 | AC125 | HCT 116 | C969(1.20); C1064(1.06); C21(1.17); C786(0.97) | LDD0560 | [5] |
LDCM0244 | AC126 | HCT 116 | C969(1.14); C1064(1.20); C21(1.40); C786(1.00) | LDD0561 | [5] |
LDCM0245 | AC127 | HCT 116 | C969(1.04); C1064(1.25); C21(1.30); C786(1.17) | LDD0562 | [5] |
LDCM0246 | AC128 | HCT 116 | C969(0.86); C1064(1.21) | LDD0563 | [5] |
LDCM0247 | AC129 | HCT 116 | C969(0.92); C1064(1.22) | LDD0564 | [5] |
LDCM0249 | AC130 | HCT 116 | C969(0.84); C1064(1.23) | LDD0566 | [5] |
LDCM0250 | AC131 | HCT 116 | C969(1.29); C1064(1.21) | LDD0567 | [5] |
LDCM0251 | AC132 | HCT 116 | C969(0.88); C1064(1.47) | LDD0568 | [5] |
LDCM0252 | AC133 | HCT 116 | C969(0.80); C1064(1.15) | LDD0569 | [5] |
LDCM0253 | AC134 | HCT 116 | C969(0.96); C1064(1.39) | LDD0570 | [5] |
LDCM0254 | AC135 | HCT 116 | C969(0.80); C1064(1.34) | LDD0571 | [5] |
LDCM0255 | AC136 | HCT 116 | C969(0.78); C1064(1.14) | LDD0572 | [5] |
LDCM0256 | AC137 | HCT 116 | C969(0.85); C1064(1.10) | LDD0573 | [5] |
LDCM0257 | AC138 | HCT 116 | C969(0.94); C1064(1.19) | LDD0574 | [5] |
LDCM0258 | AC139 | HCT 116 | C969(0.86); C1064(1.38) | LDD0575 | [5] |
LDCM0259 | AC14 | HCT 116 | C969(0.96); C1064(1.10); C187(0.76); C21(1.30) | LDD0576 | [5] |
LDCM0260 | AC140 | HCT 116 | C969(0.83); C1064(1.15) | LDD0577 | [5] |
LDCM0261 | AC141 | HCT 116 | C969(0.89); C1064(1.06) | LDD0578 | [5] |
LDCM0262 | AC142 | HCT 116 | C969(0.80); C1064(1.30) | LDD0579 | [5] |
LDCM0263 | AC143 | HCT 116 | C969(0.90); C1064(0.75); C187(1.17); C21(1.23) | LDD0580 | [5] |
LDCM0264 | AC144 | HCT 116 | C187(0.75); C1064(0.94); C969(1.02); C21(1.82) | LDD0581 | [5] |
LDCM0265 | AC145 | HCT 116 | C187(0.82); C1064(0.83); C969(0.99); C21(1.50) | LDD0582 | [5] |
LDCM0266 | AC146 | HCT 116 | C1064(0.65); C187(0.79); C969(0.80); C21(1.76) | LDD0583 | [5] |
LDCM0267 | AC147 | HCT 116 | C187(0.79); C969(0.95); C1064(1.13); C21(1.78) | LDD0584 | [5] |
LDCM0268 | AC148 | HCT 116 | C1064(0.57); C187(0.75); C969(0.89); C21(3.39) | LDD0585 | [5] |
LDCM0269 | AC149 | HCT 116 | C1064(0.58); C187(0.80); C969(0.85); C21(2.22) | LDD0586 | [5] |
LDCM0270 | AC15 | HCT 116 | C187(0.79); C969(0.86); C1064(0.87); C385(0.96) | LDD0587 | [5] |
LDCM0271 | AC150 | HCT 116 | C187(0.83); C1064(0.89); C969(0.90); C21(1.39) | LDD0588 | [5] |
LDCM0272 | AC151 | HCT 116 | C1064(0.78); C969(0.88); C187(0.95); C21(1.36) | LDD0589 | [5] |
LDCM0273 | AC152 | HCT 116 | C187(0.68); C1064(0.69); C969(0.91); C21(2.35) | LDD0590 | [5] |
LDCM0274 | AC153 | HCT 116 | C1064(0.53); C187(0.83); C969(0.93); C21(3.67) | LDD0591 | [5] |
LDCM0621 | AC154 | HCT 116 | C969(0.95); C1064(0.75); C187(0.79); C21(1.87) | LDD2158 | [5] |
LDCM0622 | AC155 | HCT 116 | C969(0.92); C1064(0.69); C187(0.71); C21(1.57) | LDD2159 | [5] |
LDCM0623 | AC156 | HCT 116 | C969(0.94); C1064(0.74); C187(0.72); C21(1.05) | LDD2160 | [5] |
LDCM0624 | AC157 | HCT 116 | C969(1.08); C1064(0.73); C187(0.89); C21(1.01) | LDD2161 | [5] |
LDCM0276 | AC17 | HCT 116 | C786(0.83); C21(0.87); C1064(0.93); C385(0.98) | LDD0593 | [5] |
LDCM0277 | AC18 | HCT 116 | C786(0.57); C1064(0.96); C187(1.05); C969(1.18) | LDD0594 | [5] |
LDCM0278 | AC19 | HCT 116 | C786(0.78); C21(0.87); C187(0.97); C1064(1.00) | LDD0595 | [5] |
LDCM0279 | AC2 | HCT 116 | C969(0.78); C385(0.83); C187(1.04); C1064(1.05) | LDD0596 | [5] |
LDCM0280 | AC20 | HCT 116 | C786(0.79); C187(0.87); C1064(0.95); C21(1.03) | LDD0597 | [5] |
LDCM0281 | AC21 | HCT 116 | C786(0.73); C21(0.81); C1064(0.91); C187(0.93) | LDD0598 | [5] |
LDCM0282 | AC22 | HCT 116 | C21(0.84); C1064(0.85); C385(0.92); C786(0.94) | LDD0599 | [5] |
LDCM0283 | AC23 | HCT 116 | C1064(0.81); C786(0.87); C21(0.95); C187(0.95) | LDD0600 | [5] |
LDCM0284 | AC24 | HCT 116 | C21(0.61); C786(0.74); C1064(0.94); C187(1.01) | LDD0601 | [5] |
LDCM0285 | AC25 | HCT 116 | C187(0.88); C969(0.92); C1064(0.93); C385(0.97) | LDD0602 | [5] |
LDCM0286 | AC26 | HCT 116 | C187(0.76); C969(0.89); C1064(0.96); C786(1.02) | LDD0603 | [5] |
LDCM0287 | AC27 | HCT 116 | C187(0.76); C969(0.81); C1064(0.89); C786(1.03) | LDD0604 | [5] |
LDCM0288 | AC28 | HCT 116 | C187(0.73); C969(0.83); C1064(0.90); C786(1.10) | LDD0605 | [5] |
LDCM0289 | AC29 | HCT 116 | C187(0.69); C969(0.80); C1064(0.86); C786(0.86) | LDD0606 | [5] |
LDCM0290 | AC3 | HCT 116 | C385(0.78); C969(0.81); C1064(1.14); C187(1.23) | LDD0607 | [5] |
LDCM0291 | AC30 | HCT 116 | C187(0.67); C1064(0.80); C786(0.94); C969(0.97) | LDD0608 | [5] |
LDCM0292 | AC31 | HCT 116 | C187(0.66); C969(0.85); C1064(0.85); C786(1.00) | LDD0609 | [5] |
LDCM0293 | AC32 | HCT 116 | C187(0.72); C969(0.75); C1064(0.97); C786(1.05) | LDD0610 | [5] |
LDCM0294 | AC33 | HCT 116 | C187(0.75); C969(0.88); C1064(0.89); C786(0.91) | LDD0611 | [5] |
LDCM0295 | AC34 | HCT 116 | C187(0.73); C786(0.82); C969(0.88); C1064(0.94) | LDD0612 | [5] |
LDCM0296 | AC35 | HCT 116 | C1064(0.96); C187(0.97); C969(1.04); C786(1.05) | LDD0613 | [5] |
LDCM0297 | AC36 | HCT 116 | C786(0.87); C969(1.01); C187(1.09); C1064(1.17) | LDD0614 | [5] |
LDCM0298 | AC37 | HCT 116 | C786(0.93); C969(1.02); C187(1.10); C1064(1.20) | LDD0615 | [5] |
LDCM0299 | AC38 | HCT 116 | C786(0.91); C969(1.02); C1064(1.06); C187(1.16) | LDD0616 | [5] |
LDCM0300 | AC39 | HCT 116 | C786(0.97); C969(0.98); C1064(1.10); C187(1.14) | LDD0617 | [5] |
LDCM0301 | AC4 | HCT 116 | C385(0.79); C969(0.81); C1064(1.21); C187(1.27) | LDD0618 | [5] |
LDCM0302 | AC40 | HCT 116 | C786(0.78); C187(1.04); C1064(1.04); C969(1.12) | LDD0619 | [5] |
LDCM0303 | AC41 | HCT 116 | C786(0.96); C969(1.05); C187(1.08); C1064(1.21) | LDD0620 | [5] |
LDCM0304 | AC42 | HCT 116 | C786(0.88); C1064(1.11); C187(1.17); C969(1.18) | LDD0621 | [5] |
LDCM0305 | AC43 | HCT 116 | C786(0.99); C969(1.01); C187(1.10); C1064(1.24) | LDD0622 | [5] |
LDCM0306 | AC44 | HCT 116 | C786(0.98); C969(1.08); C187(1.12); C1064(1.17) | LDD0623 | [5] |
LDCM0307 | AC45 | HCT 116 | C786(0.84); C969(1.06); C187(1.09); C1064(1.18) | LDD0624 | [5] |
LDCM0308 | AC46 | HCT 116 | C187(0.87); C1064(0.97); C969(1.00) | LDD0625 | [5] |
LDCM0309 | AC47 | HCT 116 | C1064(0.88); C187(0.90); C969(1.09) | LDD0626 | [5] |
LDCM0310 | AC48 | HCT 116 | C969(0.99); C187(1.06); C1064(1.15) | LDD0627 | [5] |
LDCM0311 | AC49 | HCT 116 | C1064(0.87); C187(0.88); C969(1.30) | LDD0628 | [5] |
LDCM0312 | AC5 | HCT 116 | C385(0.75); C969(0.81); C1064(1.12); C187(1.18) | LDD0629 | [5] |
LDCM0313 | AC50 | HCT 116 | C187(0.93); C1064(1.02); C969(1.10) | LDD0630 | [5] |
LDCM0314 | AC51 | HCT 116 | C1064(0.94); C969(1.16); C187(1.28) | LDD0631 | [5] |
LDCM0315 | AC52 | HCT 116 | C969(0.96); C1064(0.97); C187(1.11) | LDD0632 | [5] |
LDCM0316 | AC53 | HCT 116 | C187(0.89); C1064(0.91); C969(1.08) | LDD0633 | [5] |
LDCM0317 | AC54 | HCT 116 | C187(0.90); C969(1.10); C1064(1.15) | LDD0634 | [5] |
LDCM0318 | AC55 | HCT 116 | C187(0.85); C969(1.06); C1064(1.23) | LDD0635 | [5] |
LDCM0319 | AC56 | HCT 116 | C1064(0.81); C187(0.91); C969(1.27) | LDD0636 | [5] |
LDCM0320 | AC57 | HCT 116 | C187(0.69); C969(0.91) | LDD0637 | [5] |
LDCM0321 | AC58 | HCT 116 | C187(0.93); C969(0.96) | LDD0638 | [5] |
LDCM0322 | AC59 | HCT 116 | C187(0.86); C969(0.87) | LDD0639 | [5] |
LDCM0323 | AC6 | HCT 116 | C187(0.76); C969(0.94); C1064(1.08); C385(1.14) | LDD0640 | [5] |
LDCM0324 | AC60 | HCT 116 | C969(0.88); C187(0.91) | LDD0641 | [5] |
LDCM0325 | AC61 | HCT 116 | C187(0.72); C969(0.82) | LDD0642 | [5] |
LDCM0326 | AC62 | HCT 116 | C187(0.89); C969(0.91) | LDD0643 | [5] |
LDCM0327 | AC63 | HCT 116 | C187(0.81); C969(0.83) | LDD0644 | [5] |
LDCM0328 | AC64 | HCT 116 | C969(0.88); C187(0.90) | LDD0645 | [5] |
LDCM0329 | AC65 | HCT 116 | C969(0.91); C187(0.94) | LDD0646 | [5] |
LDCM0330 | AC66 | HCT 116 | C969(0.89); C187(0.98) | LDD0647 | [5] |
LDCM0331 | AC67 | HCT 116 | C187(0.76); C969(0.81) | LDD0648 | [5] |
LDCM0332 | AC68 | HCT 116 | C385(0.89); C969(0.89); C1064(0.96); C187(1.12) | LDD0649 | [5] |
LDCM0333 | AC69 | HCT 116 | C385(0.81); C1064(0.87); C969(1.01); C187(1.02) | LDD0650 | [5] |
LDCM0334 | AC7 | HCT 116 | C187(0.79); C969(0.94); C21(1.08); C1064(1.08) | LDD0651 | [5] |
LDCM0335 | AC70 | HCT 116 | C187(0.84); C385(0.85); C969(0.89); C1064(0.97) | LDD0652 | [5] |
LDCM0336 | AC71 | HCT 116 | C969(0.97); C385(0.99); C1064(1.30); C187(1.39) | LDD0653 | [5] |
LDCM0337 | AC72 | HCT 116 | C385(0.93); C1064(1.00); C969(1.01); C187(1.14) | LDD0654 | [5] |
LDCM0338 | AC73 | HCT 116 | C1064(1.00); C969(1.00); C385(1.02); C187(1.09) | LDD0655 | [5] |
LDCM0339 | AC74 | HCT 116 | C385(0.95); C1064(1.01); C969(1.03); C187(1.09) | LDD0656 | [5] |
LDCM0340 | AC75 | HCT 116 | C385(0.91); C1064(1.02); C969(1.08); C187(1.32) | LDD0657 | [5] |
LDCM0341 | AC76 | HCT 116 | C385(0.91); C969(1.04); C187(1.07); C1064(1.16) | LDD0658 | [5] |
LDCM0342 | AC77 | HCT 116 | C385(0.92); C969(0.93); C1064(1.09); C187(1.19) | LDD0659 | [5] |
LDCM0343 | AC78 | HCT 116 | C385(0.89); C969(0.95); C1064(1.16); C187(1.36) | LDD0660 | [5] |
LDCM0344 | AC79 | HCT 116 | C385(0.88); C1064(0.89); C969(1.04); C187(1.34) | LDD0661 | [5] |
LDCM0345 | AC8 | HCT 116 | C187(0.74); C1064(0.88); C969(1.00); C385(1.17) | LDD0662 | [5] |
LDCM0346 | AC80 | HCT 116 | C1064(0.93); C385(0.94); C969(1.05); C187(1.08) | LDD0663 | [5] |
LDCM0347 | AC81 | HCT 116 | C385(0.87); C1064(0.87); C187(1.04); C969(1.06) | LDD0664 | [5] |
LDCM0348 | AC82 | HCT 116 | C385(0.92); C1064(1.02); C969(1.11); C187(1.12) | LDD0665 | [5] |
LDCM0349 | AC83 | HCT 116 | C786(0.57); C969(0.83); C187(1.16); C1064(1.18) | LDD0666 | [5] |
LDCM0350 | AC84 | HCT 116 | C786(0.62); C969(0.83); C187(1.16); C1064(1.27) | LDD0667 | [5] |
LDCM0351 | AC85 | HCT 116 | C786(0.79); C969(0.82); C1064(1.15); C187(1.16) | LDD0668 | [5] |
LDCM0352 | AC86 | HCT 116 | C786(0.85); C969(0.88); C1064(1.07); C187(1.13) | LDD0669 | [5] |
LDCM0353 | AC87 | HCT 116 | C786(0.78); C969(0.84); C385(0.98); C1064(1.06) | LDD0670 | [5] |
LDCM0354 | AC88 | HCT 116 | C786(0.72); C969(0.90); C385(1.02); C187(1.18) | LDD0671 | [5] |
LDCM0355 | AC89 | HCT 116 | C786(0.65); C969(0.84); C1064(1.08); C385(1.12) | LDD0672 | [5] |
LDCM0357 | AC90 | HCT 116 | C385(0.95); C187(1.00); C1064(1.05); C969(1.06) | LDD0674 | [5] |
LDCM0358 | AC91 | HCT 116 | C786(0.55); C969(0.83); C385(1.08); C187(1.13) | LDD0675 | [5] |
LDCM0359 | AC92 | HCT 116 | C786(0.63); C969(0.84); C385(1.09); C187(1.13) | LDD0676 | [5] |
LDCM0360 | AC93 | HCT 116 | C786(0.69); C969(0.83); C1064(1.06); C187(1.20) | LDD0677 | [5] |
LDCM0361 | AC94 | HCT 116 | C786(0.80); C969(0.93); C385(1.26); C1064(1.36) | LDD0678 | [5] |
LDCM0362 | AC95 | HCT 116 | C786(0.70); C969(0.80); C385(0.90); C1064(1.09) | LDD0679 | [5] |
LDCM0363 | AC96 | HCT 116 | C786(0.73); C969(0.84); C385(1.15); C1064(1.28) | LDD0680 | [5] |
LDCM0364 | AC97 | HCT 116 | C786(0.74); C969(0.86); C385(1.04); C187(1.10) | LDD0681 | [5] |
LDCM0365 | AC98 | HCT 116 | C969(0.65); C786(0.99); C21(1.32) | LDD0682 | [5] |
LDCM0366 | AC99 | HCT 116 | C969(0.77); C21(0.78); C786(1.24) | LDD0683 | [5] |
LDCM0248 | AKOS034007472 | HCT 116 | C969(0.72); C1064(1.04); C187(1.02); C21(1.15) | LDD0565 | [5] |
LDCM0356 | AKOS034007680 | HCT 116 | C969(0.75); C187(0.82); C385(0.90); C1064(1.12) | LDD0673 | [5] |
LDCM0275 | AKOS034007705 | HCT 116 | C187(0.75); C969(0.87); C385(1.04); C1064(1.12) | LDD0592 | [5] |
LDCM0367 | CL1 | HCT 116 | C1064(0.91); C969(1.06); C187(1.11); C385(1.68) | LDD0684 | [5] |
LDCM0368 | CL10 | HCT 116 | C385(1.00); C969(1.01); C187(1.05); C1064(1.13) | LDD0685 | [5] |
LDCM0369 | CL100 | HCT 116 | C385(0.83); C187(0.92); C969(0.94); C1064(1.09) | LDD0686 | [5] |
LDCM0370 | CL101 | HCT 116 | C187(0.79); C969(0.96); C1064(0.98); C385(1.14) | LDD0687 | [5] |
LDCM0371 | CL102 | HCT 116 | C187(0.83); C1064(0.91); C969(0.92); C385(0.99) | LDD0688 | [5] |
LDCM0372 | CL103 | HCT 116 | C969(0.76); C187(0.81); C21(1.02); C1064(1.10) | LDD0689 | [5] |
LDCM0373 | CL104 | HCT 116 | C187(0.83); C969(0.93); C385(0.96); C21(1.09) | LDD0690 | [5] |
LDCM0374 | CL105 | HCT 116 | C786(0.74); C1064(0.94); C187(0.96); C969(1.10) | LDD0691 | [5] |
LDCM0375 | CL106 | HCT 116 | C786(0.54); C1064(0.97); C187(1.02); C969(1.11) | LDD0692 | [5] |
LDCM0376 | CL107 | HCT 116 | C786(0.70); C187(1.01); C1064(1.02); C21(1.19) | LDD0693 | [5] |
LDCM0377 | CL108 | HCT 116 | C786(0.58); C187(0.97); C1064(1.01); C969(1.11) | LDD0694 | [5] |
LDCM0378 | CL109 | HCT 116 | C786(0.76); C1064(0.87); C21(0.89); C187(0.93) | LDD0695 | [5] |
LDCM0379 | CL11 | HCT 116 | C385(0.88); C187(1.01); C1064(1.09); C969(1.09) | LDD0696 | [5] |
LDCM0380 | CL110 | HCT 116 | C786(0.61); C187(0.78); C1064(0.98); C21(1.07) | LDD0697 | [5] |
LDCM0381 | CL111 | HCT 116 | C786(0.68); C187(0.80); C21(0.99); C1064(1.06) | LDD0698 | [5] |
LDCM0382 | CL112 | HCT 116 | C786(0.91); C187(0.93); C1064(0.96); C969(1.03) | LDD0699 | [5] |
LDCM0383 | CL113 | HCT 116 | C187(0.69); C786(0.86); C969(0.89); C1064(0.92) | LDD0700 | [5] |
LDCM0384 | CL114 | HCT 116 | C187(0.66); C969(0.81); C786(0.87); C1064(0.88) | LDD0701 | [5] |
LDCM0385 | CL115 | HCT 116 | C187(0.70); C1064(0.91); C969(0.94); C786(1.04) | LDD0702 | [5] |
LDCM0386 | CL116 | HCT 116 | C187(0.80); C969(0.84); C1064(1.00); C786(1.02) | LDD0703 | [5] |
LDCM0387 | CL117 | HCT 116 | C786(0.89); C187(0.94); C1064(0.97); C969(1.73) | LDD0704 | [5] |
LDCM0388 | CL118 | HCT 116 | C969(0.97); C786(0.97); C1064(1.01); C187(1.09) | LDD0705 | [5] |
LDCM0389 | CL119 | HCT 116 | C786(0.90); C969(0.93); C1064(0.99); C187(1.02) | LDD0706 | [5] |
LDCM0390 | CL12 | HCT 116 | C385(1.10); C187(1.10); C969(1.14); C1064(1.45) | LDD0707 | [5] |
LDCM0391 | CL120 | HCT 116 | C786(0.95); C969(0.99); C187(1.15); C1064(1.24) | LDD0708 | [5] |
LDCM0392 | CL121 | HCT 116 | C187(0.78); C969(0.85); C1064(0.93) | LDD0709 | [5] |
LDCM0393 | CL122 | HCT 116 | C1064(0.87); C187(0.91); C969(1.08) | LDD0710 | [5] |
LDCM0394 | CL123 | HCT 116 | C1064(0.86); C187(0.94); C969(1.22) | LDD0711 | [5] |
LDCM0395 | CL124 | HCT 116 | C187(0.90); C1064(0.95); C969(1.11) | LDD0712 | [5] |
LDCM0396 | CL125 | HCT 116 | C969(0.87); C187(1.16) | LDD0713 | [5] |
LDCM0397 | CL126 | HCT 116 | C969(0.91); C187(1.06) | LDD0714 | [5] |
LDCM0398 | CL127 | HCT 116 | C969(0.83); C187(0.85) | LDD0715 | [5] |
LDCM0399 | CL128 | HCT 116 | C187(0.84); C969(0.85) | LDD0716 | [5] |
LDCM0400 | CL13 | HCT 116 | C187(0.86); C385(1.07); C1064(1.07); C969(1.19) | LDD0717 | [5] |
LDCM0401 | CL14 | HCT 116 | C385(1.11); C969(1.17); C1064(1.19); C187(1.20) | LDD0718 | [5] |
LDCM0402 | CL15 | HCT 116 | C969(0.99); C187(1.00); C1064(1.14); C385(1.24) | LDD0719 | [5] |
LDCM0403 | CL16 | HCT 116 | C786(0.72); C1064(0.80); C969(0.87) | LDD0720 | [5] |
LDCM0404 | CL17 | HCT 116 | C969(0.91); C786(0.91); C1064(0.99) | LDD0721 | [5] |
LDCM0405 | CL18 | HCT 116 | C1064(0.68); C786(0.71); C969(0.78) | LDD0722 | [5] |
LDCM0406 | CL19 | HCT 116 | C786(0.72); C1064(0.79); C969(0.86) | LDD0723 | [5] |
LDCM0407 | CL2 | HCT 116 | C969(1.02); C187(1.20); C385(1.20); C1064(1.27) | LDD0724 | [5] |
LDCM0408 | CL20 | HCT 116 | C969(0.78); C1064(0.83); C786(0.92) | LDD0725 | [5] |
LDCM0409 | CL21 | HCT 116 | C1064(0.88); C786(0.91); C969(1.00) | LDD0726 | [5] |
LDCM0410 | CL22 | HCT 116 | C786(0.92); C969(0.98); C1064(1.01) | LDD0727 | [5] |
LDCM0411 | CL23 | HCT 116 | C786(0.76); C1064(0.77); C969(1.09) | LDD0728 | [5] |
LDCM0412 | CL24 | HCT 116 | C786(0.64); C1064(0.84); C969(0.86) | LDD0729 | [5] |
LDCM0413 | CL25 | HCT 116 | C969(0.82); C1064(0.76); C786(0.75) | LDD0730 | [5] |
LDCM0414 | CL26 | HCT 116 | C969(0.90); C1064(0.77); C786(0.70) | LDD0731 | [5] |
LDCM0415 | CL27 | HCT 116 | C969(0.90); C1064(0.98); C786(1.09) | LDD0732 | [5] |
LDCM0416 | CL28 | HCT 116 | C969(0.87); C1064(0.77); C786(0.95) | LDD0733 | [5] |
LDCM0417 | CL29 | HCT 116 | C969(0.86); C1064(0.88); C786(0.87) | LDD0734 | [5] |
LDCM0418 | CL3 | HCT 116 | C969(1.06); C1064(1.06); C187(0.99); C385(0.94) | LDD0735 | [5] |
LDCM0419 | CL30 | HCT 116 | C969(0.96); C1064(0.78); C786(0.88) | LDD0736 | [5] |
LDCM0420 | CL31 | HCT 116 | C969(0.97); C1064(1.15); C187(1.00); C786(0.71) | LDD0737 | [5] |
LDCM0421 | CL32 | HCT 116 | C969(0.84); C1064(0.87); C187(0.72); C786(0.59) | LDD0738 | [5] |
LDCM0422 | CL33 | HCT 116 | C969(1.06); C1064(0.81); C187(0.76); C786(0.43) | LDD0739 | [5] |
LDCM0423 | CL34 | HCT 116 | C969(1.04); C1064(0.85); C187(0.70); C786(0.51) | LDD0740 | [5] |
LDCM0424 | CL35 | HCT 116 | C969(0.89); C1064(1.07); C187(0.70); C786(0.67) | LDD0741 | [5] |
LDCM0425 | CL36 | HCT 116 | C969(1.17); C1064(0.84); C187(0.76); C786(0.78) | LDD0742 | [5] |
LDCM0426 | CL37 | HCT 116 | C969(0.94); C1064(1.08); C187(0.71); C786(0.43) | LDD0743 | [5] |
LDCM0428 | CL39 | HCT 116 | C969(1.07); C1064(0.90); C187(0.76); C786(0.51) | LDD0745 | [5] |
LDCM0429 | CL4 | HCT 116 | C969(0.94); C1064(1.03); C187(1.01); C385(0.99) | LDD0746 | [5] |
LDCM0430 | CL40 | HCT 116 | C969(0.89); C1064(0.98); C187(0.66); C786(0.41) | LDD0747 | [5] |
LDCM0431 | CL41 | HCT 116 | C969(1.09); C1064(0.98); C187(0.75); C786(0.58) | LDD0748 | [5] |
LDCM0432 | CL42 | HCT 116 | C969(1.12); C1064(0.82); C187(0.65); C786(0.50) | LDD0749 | [5] |
LDCM0433 | CL43 | HCT 116 | C969(1.02); C1064(0.89); C187(0.63); C786(0.39) | LDD0750 | [5] |
LDCM0434 | CL44 | HCT 116 | C969(1.08); C1064(0.97); C187(0.59); C786(0.51) | LDD0751 | [5] |
LDCM0435 | CL45 | HCT 116 | C969(0.99); C1064(0.97); C187(0.68); C786(0.39) | LDD0752 | [5] |
LDCM0436 | CL46 | HCT 116 | C969(1.14); C385(0.82) | LDD0753 | [5] |
LDCM0437 | CL47 | HCT 116 | C969(1.21); C385(0.93) | LDD0754 | [5] |
LDCM0438 | CL48 | HCT 116 | C969(1.25); C385(0.90) | LDD0755 | [5] |
LDCM0439 | CL49 | HCT 116 | C969(1.25); C385(0.92) | LDD0756 | [5] |
LDCM0440 | CL5 | HCT 116 | C969(1.02); C1064(1.48); C187(1.15); C385(1.17) | LDD0757 | [5] |
LDCM0441 | CL50 | HCT 116 | C969(1.15); C385(1.04) | LDD0758 | [5] |
LDCM0442 | CL51 | HCT 116 | C969(1.08); C385(1.00) | LDD0759 | [5] |
LDCM0443 | CL52 | HCT 116 | C969(0.93); C385(0.95) | LDD0760 | [5] |
LDCM0444 | CL53 | HCT 116 | C969(1.29); C385(0.92) | LDD0761 | [5] |
LDCM0445 | CL54 | HCT 116 | C969(1.31); C385(1.03) | LDD0762 | [5] |
LDCM0446 | CL55 | HCT 116 | C969(1.14); C385(0.99) | LDD0763 | [5] |
LDCM0447 | CL56 | HCT 116 | C969(1.04); C385(0.86) | LDD0764 | [5] |
LDCM0448 | CL57 | HCT 116 | C969(1.16); C385(0.93) | LDD0765 | [5] |
LDCM0449 | CL58 | HCT 116 | C969(1.04); C385(0.87) | LDD0766 | [5] |
LDCM0450 | CL59 | HCT 116 | C969(1.06); C385(0.97) | LDD0767 | [5] |
LDCM0451 | CL6 | HCT 116 | C969(1.04); C1064(0.87); C187(0.90); C385(1.04) | LDD0768 | [5] |
LDCM0452 | CL60 | HCT 116 | C969(1.08); C385(0.95) | LDD0769 | [5] |
LDCM0453 | CL61 | HCT 116 | C969(0.76); C1064(0.88); C21(1.01); C385(1.16) | LDD0770 | [5] |
LDCM0454 | CL62 | HCT 116 | C969(0.84); C1064(0.90); C21(1.02); C385(1.14) | LDD0771 | [5] |
LDCM0455 | CL63 | HCT 116 | C969(0.72); C1064(0.81); C21(1.19); C385(1.24) | LDD0772 | [5] |
LDCM0456 | CL64 | HCT 116 | C969(0.83); C1064(0.91); C21(1.42); C385(1.22) | LDD0773 | [5] |
LDCM0457 | CL65 | HCT 116 | C969(0.81); C1064(0.93); C21(1.14); C385(1.05) | LDD0774 | [5] |
LDCM0458 | CL66 | HCT 116 | C969(0.76); C1064(0.86); C21(1.92); C385(1.00) | LDD0775 | [5] |
LDCM0459 | CL67 | HCT 116 | C969(0.82); C1064(0.88); C21(1.58); C385(0.87) | LDD0776 | [5] |
LDCM0460 | CL68 | HCT 116 | C969(0.79); C1064(0.86); C21(1.67); C385(0.83) | LDD0777 | [5] |
LDCM0461 | CL69 | HCT 116 | C969(0.80); C1064(0.67); C21(1.19); C385(1.40) | LDD0778 | [5] |
LDCM0462 | CL7 | HCT 116 | C969(1.01); C1064(0.99); C187(0.89); C385(1.28) | LDD0779 | [5] |
LDCM0463 | CL70 | HCT 116 | C969(0.80); C1064(0.77); C21(1.28); C385(0.90) | LDD0780 | [5] |
LDCM0464 | CL71 | HCT 116 | C969(0.79); C1064(0.80); C21(1.21); C385(0.83) | LDD0781 | [5] |
LDCM0465 | CL72 | HCT 116 | C969(0.87); C1064(0.74); C21(1.18); C385(0.96) | LDD0782 | [5] |
LDCM0466 | CL73 | HCT 116 | C969(1.06); C1064(0.85); C21(1.14); C385(1.07) | LDD0783 | [5] |
LDCM0467 | CL74 | HCT 116 | C969(0.84); C1064(0.88); C21(1.38); C385(0.88) | LDD0784 | [5] |
LDCM0469 | CL76 | HCT 116 | C969(0.82); C1064(1.14); C187(0.74); C21(1.16) | LDD0786 | [5] |
LDCM0470 | CL77 | HCT 116 | C969(0.90); C1064(1.22); C187(0.73); C21(1.02) | LDD0787 | [5] |
LDCM0471 | CL78 | HCT 116 | C969(0.37); C1064(1.27); C187(0.69); C21(1.16) | LDD0788 | [5] |
LDCM0472 | CL79 | HCT 116 | C969(0.57); C1064(1.03); C187(0.81); C21(1.55) | LDD0789 | [5] |
LDCM0473 | CL8 | HCT 116 | C969(0.98); C1064(1.17); C187(0.93); C385(0.98) | LDD0790 | [5] |
LDCM0474 | CL80 | HCT 116 | C969(20.00); C1064(1.29); C187(0.78); C21(1.27) | LDD0791 | [5] |
LDCM0475 | CL81 | HCT 116 | C969(0.66); C1064(1.26); C187(0.77); C21(1.26) | LDD0792 | [5] |
LDCM0476 | CL82 | HCT 116 | C969(0.48); C1064(1.34); C187(0.66); C21(2.19) | LDD0793 | [5] |
LDCM0477 | CL83 | HCT 116 | C969(0.69); C1064(1.17); C187(0.75); C21(1.78) | LDD0794 | [5] |
LDCM0478 | CL84 | HCT 116 | C969(0.61); C1064(0.96); C187(0.67); C21(2.43) | LDD0795 | [5] |
LDCM0479 | CL85 | HCT 116 | C969(0.57); C1064(1.12); C187(0.79); C21(1.28) | LDD0796 | [5] |
LDCM0480 | CL86 | HCT 116 | C969(0.49); C1064(1.26); C187(0.78); C21(1.11) | LDD0797 | [5] |
LDCM0481 | CL87 | HCT 116 | C969(0.60); C1064(1.12); C187(0.79); C21(1.29) | LDD0798 | [5] |
LDCM0482 | CL88 | HCT 116 | C969(0.70); C1064(1.39); C187(0.76); C21(1.75) | LDD0799 | [5] |
LDCM0483 | CL89 | HCT 116 | C969(0.67); C1064(1.32); C187(0.74); C21(3.00) | LDD0800 | [5] |
LDCM0484 | CL9 | HCT 116 | C969(0.95); C1064(1.01); C187(1.02); C385(1.36) | LDD0801 | [5] |
LDCM0485 | CL90 | HCT 116 | C969(0.81); C1064(1.45); C187(1.05); C21(0.96) | LDD0802 | [5] |
LDCM0486 | CL91 | HCT 116 | C969(0.80); C1064(0.99); C187(0.96); C21(1.22) | LDD0803 | [5] |
LDCM0487 | CL92 | HCT 116 | C969(1.08); C1064(0.93); C187(0.78); C21(1.14) | LDD0804 | [5] |
LDCM0488 | CL93 | HCT 116 | C969(1.12); C1064(1.03); C187(1.37); C21(1.19) | LDD0805 | [5] |
LDCM0489 | CL94 | HCT 116 | C969(1.06); C1064(0.97); C187(0.93); C21(1.33) | LDD0806 | [5] |
LDCM0490 | CL95 | HCT 116 | C969(0.91); C1064(0.97); C187(1.14); C21(1.37) | LDD0807 | [5] |
LDCM0491 | CL96 | HCT 116 | C969(0.78); C1064(0.94); C187(1.04); C21(1.26) | LDD0808 | [5] |
LDCM0492 | CL97 | HCT 116 | C969(0.86); C1064(1.01); C187(1.20); C21(1.56) | LDD0809 | [5] |
LDCM0493 | CL98 | HCT 116 | C969(0.77); C1064(1.01); C187(1.04); C21(1.51) | LDD0810 | [5] |
LDCM0494 | CL99 | HCT 116 | C969(0.75); C1064(1.17); C187(1.09); C21(1.45) | LDD0811 | [5] |
LDCM0495 | E2913 | HEK-293T | C369(1.06); C1064(1.01); C187(0.83); C969(0.92) | LDD1698 | [14] |
LDCM0625 | F8 | Ramos | C21(0.42); C385(1.45) | LDD2187 | [15] |
LDCM0572 | Fragment10 | Ramos | C187(0.59) | LDD2189 | [15] |
LDCM0573 | Fragment11 | Ramos | C21(0.47); C385(0.43) | LDD2190 | [15] |
LDCM0574 | Fragment12 | Ramos | C187(0.86) | LDD2191 | [15] |
LDCM0576 | Fragment14 | Ramos | C21(1.15); C385(1.03) | LDD2193 | [15] |
LDCM0579 | Fragment20 | Ramos | C187(0.67) | LDD2194 | [15] |
LDCM0580 | Fragment21 | Ramos | C385(0.87) | LDD2195 | [15] |
LDCM0586 | Fragment28 | Ramos | C21(0.58); C385(1.02) | LDD2198 | [15] |
LDCM0589 | Fragment31 | Ramos | C385(1.09) | LDD2200 | [15] |
LDCM0468 | Fragment33 | HCT 116 | C969(0.77); C1064(0.87); C21(1.45); C385(1.01) | LDD0785 | [5] |
LDCM0566 | Fragment4 | Ramos | C21(0.67); C385(0.99) | LDD2184 | [15] |
LDCM0427 | Fragment51 | HCT 116 | C969(1.11); C1064(0.89); C187(0.64); C786(0.38) | LDD0744 | [5] |
LDCM0614 | Fragment56 | Ramos | C385(0.92) | LDD2205 | [15] |
LDCM0569 | Fragment7 | Ramos | C385(0.94) | LDD2186 | [15] |
LDCM0022 | KB02 | HCT 116 | C1064(2.12); C969(3.68); C385(9.24) | LDD0080 | [5] |
LDCM0023 | KB03 | HCT 116 | C1064(2.10); C969(4.69); C385(1.79) | LDD0081 | [5] |
LDCM0024 | KB05 | HCT 116 | C1064(3.26); C969(2.50); C385(2.23) | LDD0082 | [5] |
LDCM0109 | NEM | HeLa | N.A. | LDD0224 | [4] |
LDCM0526 | Nucleophilic fragment 26a | MDA-MB-231 | C1064(2.93) | LDD2119 | [2] |
LDCM0530 | Nucleophilic fragment 28a | MDA-MB-231 | C1064(1.46) | LDD2123 | [2] |
LDCM0536 | Nucleophilic fragment 31 | MDA-MB-231 | C1064(1.96) | LDD2129 | [2] |
The Interaction Atlas With This Target
References