Details of the Probe

General Information of Probe

Probe ID
LDPC0429
Probe Name
C193
Synonyms
Z4282860001
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 362.4
Lipid-water partition coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C21H22N4O2
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[(2-methoxyphenyl)-pyridin-2-ylmethyl]propanamide
Canonical SMILES
COC1=CC=CC=C1C(C2=CC=CC=N2)NC(=O)CCC3(N=N3)CCC#C
InChI
InChI=1S/C21H22N4O2/c1-3-4-13-21(24-25-21)14-12-19(26)23-20(17-10-7-8-15-22-17)16-9-5-6-11-18(16)27-2/h1,5-11,15,20H,4,12-14H2,2H3,(H,23,26)
InChIKey
YIRAKZJMRWANTE-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

91 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
5'-3' exonuclease PLD3 (PLD3) LDTP08476 8.63  LDD1869 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 7.46  LDD1869 
AMP deaminase 2 (AMPD2) LDTP05289 5.46  LDD1869 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 8.82  LDD1869 
ATP-dependent DNA/RNA helicase DHX36 (DHX36) LDTP11841 6.19  LDD1869 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 11.96  LDD1869 
Beta-galactosidase (GLB1) LDTP02837 11.88  LDD1869 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 5.86  LDD1869 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 5.03  LDD1869 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 19.16  LDD1869 
Carboxymethylenebutenolidase homolog (CMBL) LDTP10215 15.24  LDD1869 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 14.93  LDD1869 
CCR4-NOT transcription complex subunit 4 (CNOT4) LDTP01640 12.30  LDD1869 
Ceramide synthase 2 (CERS2) LDTP10329 5.62  LDD1869 
Choline kinase alpha (CHKA) LDTP03787 5.24  LDD1869 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 32.90  LDD1869 
Cytochrome b5 type B (CYB5B) LDTP00697 11.08  LDD1869 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 6.45  LDD1869 
DCN1-like protein 5 (DCUN1D5) LDTP11199 20.68  LDD1869 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 5.39  LDD1869 
Delta(24)-sterol reductase (DHCR24) LDTP06375 5.82  LDD1869 
Dermatan-sulfate epimerase (DSE) LDTP13504 23.75  LDD1869 
Dihydrofolate reductase (DHFR) LDTP01769 8.17  LDD1869 
Dihydropteridine reductase (QDPR) LDTP02342 13.36  LDD1869 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 5.90  LDD1869 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) LDTP09388 5.06  LDD1869 
E3 ubiquitin-protein ligase ARIH1 (ARIH1) LDTP14079 5.46  LDD1869 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 5.46  LDD1869 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 7.73  LDD1869 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 13.93  LDD1869 
Exonuclease 1 (EXO1) LDTP13751 4.92  LDD1869 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 7.06  LDD1869 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 5.54  LDD1869 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 5.70  LDD1869 
Glycogen synthase kinase-3 alpha (GSK3A) LDTP04318 7.89  LDD1869 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 5.06  LDD1869 
GPI-anchor transamidase (PIGK) LDTP09835 5.86  LDD1869 
Heme oxygenase 1 (HMOX1) LDTP02359 10.78  LDD1869 
Heme oxygenase 2 (HMOX2) LDTP03540 12.91  LDD1869 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 5.78  LDD1869 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 5.98  LDD1869 
Holocytochrome c-type synthase (HCCS) LDTP04581 7.57  LDD1869 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 6.50  LDD1869 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 5.31  LDD1869 
Kinesin-like protein KIF20A (KIF20A) LDTP01535 6.23  LDD1869 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 5.39  LDD1869 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 5.82  LDD1869 
Lathosterol oxidase (SC5D) LDTP01329 6.19  LDD1869 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 8.06  LDD1869 
Lysocardiolipin acyltransferase 1 (LCLAT1) LDTP07679 7.52  LDD1869 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 8.11  LDD1869 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 21.11  LDD1869 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 11.71  LDD1869 
Lysosomal protective protein (CTSA) LDTP02505 7.62  LDD1869 
Metalloendopeptidase OMA1, mitochondrial (OMA1) LDTP10249 5.50  LDD1869 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 5.24  LDD1869 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 5.58  LDD1869 
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1) LDTP00837 13.64  LDD1869 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 4.96  LDD1869 
NADH-cytochrome b5 reductase 1 (CYB5R1) LDTP13303 6.19  LDD1869 
Oxidized purine nucleoside triphosphate hydrolase (NUDT1) LDTP03816 5.21  LDD1869 
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (PAOX) LDTP07620 6.87  LDD1869 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 10.13  LDD1869 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 13.18  LDD1869 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 7.11  LDD1869 
Presequence protease, mitochondrial (PITRM1) LDTP07003 6.41  LDD1869 
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) LDTP00645 4.96  LDD1869 
Prostaglandin reductase 2 (PTGR2) LDTP08979 5.06  LDD1869 
Prostaglandin reductase 3 (PTGR3) LDTP15422 9.32  LDD1869 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 8.40  LDD1869 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 5.54  LDD1869 
Protein O-GlcNAcase (OGA) LDTP00988 5.43  LDD1869 
Protein phosphatase 3 catalytic subunit alpha (PPP3CA) LDTP05549 6.15  LDD1869 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 5.43  LDD1869 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 10.34  LDD1869 
Putative peptidyl-tRNA hydrolase PTRHD1 (PTRHD1) LDTP19478 5.70  LDD1869 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 6.11  LDD1869 
Ras-related protein Rab-1A (RAB1A) LDTP05006 60.55  LDD1869 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 7.52  LDD1869 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 16.22  LDD1869 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 16.56  LDD1869 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 6.02  LDD1869 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 5.35  LDD1869 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 6.15  LDD1869 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 5.28  LDD1869 
Telomerase RNA component interacting RNase (TRIR) LDTP11055 5.86  LDD1869 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 5.31  LDD1869 
Thiosulfate sulfurtransferase (TST) LDTP06620 5.28  LDD1869 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 7.78  LDD1869 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 5.98  LDD1869 
Xaa-Arg dipeptidase (PM20D2) LDTP08666 5.54  LDD1869 
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⏷ Show the Full List of 91 Enzyme
51 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein theta (YWHAQ) LDTP03385 4.99  LDD1869 
45 kDa calcium-binding protein (SDF4) LDTP11116 5.39  LDD1869 
Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 7.06  LDD1869 
Anion exchange protein 2 (SLC4A2) LDTP02061 5.70  LDD1869 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 5.78  LDD1869 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 7.52  LDD1869 
Ceramide transfer protein (CERT1) LDTP14140 10.34  LDD1869 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 7.31  LDD1869 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 14.03  LDD1869 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 5.74  LDD1869 
Exocyst complex component 8 (EXOC8) LDTP08651 5.90  LDD1869 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 5.24  LDD1869 
H(+)/Cl(-) exchange transporter 6 (CLCN6) LDTP04462 5.35  LDD1869 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 5.21  LDD1869 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 5.17  LDD1869 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 16.91  LDD1869 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 6.15  LDD1869 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 8.22  LDD1869 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 4.96  LDD1869 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 39.67  LDD1869 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 25.81  LDD1869 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 13.74  LDD1869 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 16.56  LDD1869 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 7.16  LDD1869 
Mpv17-like protein 2 (MPV17L2) LDTP14952 10.06  LDD1869 
Nucleoporin NDC1 (NDC1) LDTP11213 7.26  LDD1869 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 12.82  LDD1869 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 5.90  LDD1869 
Prosaposin (PSAP) LDTP02215 5.10  LDD1869 
Protein ERGIC-53 (LMAN1) LDTP04237 18.77  LDD1869 
Protein tweety homolog 3 (TTYH3) LDTP11615 13.83  LDD1869 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 8.75  LDD1869 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 13.27  LDD1869 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 6.23  LDD1869 
Sideroflexin-1 (SFXN1) LDTP12090 5.17  LDD1869 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 11.71  LDD1869 
Signal recognition particle 14 kDa protein (SRP14) LDTP03837 4.92  LDD1869 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 11.63  LDD1869 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 6.36  LDD1869 
SUN domain-containing protein 1 (SUN1) LDTP01454 5.17  LDD1869 
Tetraspanin-10 (TSPAN10) LDTP15967 6.77  LDD1869 
Tetraspanin-3 (TSPAN3) LDTP16813 7.41  LDD1869 
Translocator protein (TSPO) LDTP03546 5.70  LDD1869 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 8.88  LDD1869 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 17.39  LDD1869 
Transmembrane protein 126A (TMEM126A) LDTP15948 8.06  LDD1869 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 9.92  LDD1869 
Vacuolar protein sorting-associated protein 29 (VPS29) LDTP13142 5.54  LDD1869 
Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 5.03  LDD1869 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 9.65  LDD1869 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 26.35  LDD1869 
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⏷ Show the Full List of 51 Transporter and channel
6 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
CDKN2A-interacting protein (CDKN2AIP) LDTP12792 5.46  LDD1869 
High mobility group protein B1 (HMGB1) LDTP02343 8.28  LDD1869 
High mobility group protein B3 (HMGB3) LDTP00612 5.46  LDD1869 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 7.89  LDD1869 
PHD finger-like domain-containing protein 5A (PHF5A) LDTP08006 14.12  LDD1869 
Transcriptional repressor p66-alpha (GATAD2A) LDTP08409 8.34  LDD1869 
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⏷ Show the Full List of 6 Transcription factor
1 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Membrane progestin receptor alpha (PAQR7) LDTP15303 27.86  LDD1869 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
HLA class I histocompatibility antigen, alpha chain E (HLA-E) LDTP02688 12.47  LDD1869 
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130 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein eta (YWHAH) LDTP05442 6.32  LDD1869 
17S U2 SnRNP complex component HTATSF1 (HTATSF1) LDTP00849 5.17  LDD1869 
ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) LDTP08950 6.23  LDD1869 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 10.34  LDD1869 
Apolipoprotein L2 (APOL2) LDTP11076 12.73  LDD1869 
Ataxin-2 (ATXN2) LDTP10947 4.92  LDD1869 
Ataxin-2-like protein (ATXN2L) LDTP09655 5.50  LDD1869 
Bcl-2-associated transcription factor 1 (BCLAF1) LDTP12826 5.98  LDD1869 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 19.03  LDD1869 
BRISC and BRCA1-A complex member 1 (BABAM1) LDTP12737 5.28  LDD1869 
Bromodomain-containing protein 2 (BRD2) LDTP03322 5.13  LDD1869 
BUB3-interacting and GLEBS motif-containing protein ZNF207 (ZNF207) LDTP00830 9.00  LDD1869 
Calponin-3 (CNN3) LDTP06383 6.15  LDD1869 
Calumenin (CALU) LDTP00887 5.13  LDD1869 
Chromatin assembly factor 1 subunit A (CHAF1A) LDTP05750 5.17  LDD1869 
Chromobox protein homolog 1 (CBX1) LDTP05189 6.11  LDD1869 
Clustered mitochondria protein homolog (CLUH) LDTP14486 30.48  LDD1869 
Coronin-1B (CORO1B) LDTP11101 12.91  LDD1869 
DBIRD complex subunit ZNF326 (ZNF326) LDTP06952 7.46  LDD1869 
DDB1- and CUL4-associated factor 13 (DCAF13) LDTP12652 8.06  LDD1869 
DET1- and DDB1-associated protein 1 (DDA1) LDTP11312 7.46  LDD1869 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 12.47  LDD1869 
DNA polymerase epsilon subunit 3 (POLE3) LDTP12506 5.74  LDD1869 
DNA repair protein XRCC1 (XRCC1) LDTP02973 5.66  LDD1869 
Dynactin subunit 4 (DCTN4) LDTP13402 5.39  LDD1869 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 19.16  LDD1869 
Elongin-C (ELOC) LDTP06368 5.13  LDD1869 
Emerin (EMD) LDTP04356 7.21  LDD1869 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 13.36  LDD1869 
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 6.59  LDD1869 
Eukaryotic translation initiation factor 3 subunit H (EIF3H) LDTP00620 6.23  LDD1869 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 5.50  LDD1869 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 7.11  LDD1869 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 4.99  LDD1869 
Eukaryotic translation initiation factor 4H (EIF4H) LDTP06301 6.63  LDD1869 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 10.34  LDD1869 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 7.52  LDD1869 
Folliculin (FLCN) LDTP09201 5.03  LDD1869 
Ganglioside-induced differentiation-associated protein 1 (GDAP1) LDTP09324 6.87  LDD1869 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 7.62  LDD1869 
Golgi apparatus protein 1 (GLG1) LDTP09920 8.00  LDD1869 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 30.48  LDD1869 
HAUS augmin-like complex subunit 3 (HAUS3) LDTP07318 6.77  LDD1869 
Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0) LDTP05768 8.82  LDD1869 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 5.66  LDD1869 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 4.99  LDD1869 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 9.85  LDD1869 
Kinetochore protein Spc25 (SPC25) LDTP12192 6.11  LDD1869 
Large proline-rich protein BAG6 (BAG6) LDTP04094 7.73  LDD1869 
Large ribosomal subunit protein bL27m (MRPL27) LDTP16162 7.84  LDD1869 
Large ribosomal subunit protein eL19 (RPL19) LDTP05196 5.43  LDD1869 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 5.13  LDD1869 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 8.40  LDD1869 
Large ribosomal subunit protein eL29 (RPL29) LDTP04140 6.19  LDD1869 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 12.21  LDD1869 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 14.83  LDD1869 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 4.99  LDD1869 
Large ribosomal subunit protein uL24 (RPL26) LDTP04914 7.06  LDD1869 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 5.10  LDD1869 
Melanoma-associated antigen D2 (MAGED2) LDTP13657 5.50  LDD1869 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 5.03  LDD1869 
Microtubule-associated protein 4 (MAP4) LDTP03404 6.28  LDD1869 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 11.71  LDD1869 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 7.46  LDD1869 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 12.91  LDD1869 
Mortality factor 4-like protein 1 (MORF4L1) LDTP13162 6.23  LDD1869 
Neurofilament medium polypeptide (NEFM) LDTP02181 4.99  LDD1869 
NHL repeat-containing protein 2 (NHLRC2) LDTP09049 5.06  LDD1869 
Nuclear migration protein nudC (NUDC) LDTP13817 7.73  LDD1869 
Nuclear speckle splicing regulatory protein 1 (NSRP1) LDTP11709 5.21  LDD1869 
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (NUCKS1) LDTP11764 5.10  LDD1869 
Nucleobindin-1 (NUCB1) LDTP05375 9.51  LDD1869 
Nucleobindin-2 (NUCB2) LDTP05160 30.91  LDD1869 
Nucleolar protein 14 (NOP14) LDTP05087 4.96  LDD1869 
Nucleophosmin (NPM1) LDTP02164 7.06  LDD1869 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 15.03  LDD1869 
PHD finger protein 6 (PHF6) LDTP08552 8.40  LDD1869 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 6.50  LDD1869 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 4.92  LDD1869 
PRELI domain-containing protein 1, mitochondrial (PRELID1) LDTP13807 5.50  LDD1869 
Proline-rich protein PRCC (PRCC) LDTP09850 5.46  LDD1869 
Protein CEBPZOS (CEBPZOS) LDTP18883 7.16  LDD1869 
Protein CMSS1 (CMSS1) LDTP18287 5.46  LDD1869 
Protein enabled homolog (ENAH) LDTP08984 5.66  LDD1869 
Protein FAM162A (FAM162A) LDTP10056 5.70  LDD1869 
Protein FAM98B (FAM98B) LDTP06879 7.11  LDD1869 
Protein LYRIC (MTDH) LDTP08224 7.78  LDD1869 
Protein SET (SET) LDTP05277 5.86  LDD1869 
Protein unc-119 homolog B (UNC119B) LDTP00105 14.83  LDD1869 
Pumilio homolog 1 (PUM1) LDTP06174 5.70  LDD1869 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 7.84  LDD1869 
RAD50-interacting protein 1 (RINT1) LDTP07476 5.90  LDD1869 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 6.23  LDD1869 
Rap guanine nucleotide exchange factor 2 (RAPGEF2) LDTP14058 7.31  LDD1869 
Replication protein A 32 kDa subunit (RPA2) LDTP02816 11.55  LDD1869 
Reticulon-3 (RTN3) LDTP01522 22.47  LDD1869 
RNA-binding protein 10 (RBM10) LDTP05224 5.86  LDD1869 
RNA-binding protein 12 (RBM12) LDTP16096 5.39  LDD1869 
RNA-binding protein 14 (RBM14) LDTP10684 7.78  LDD1869 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 5.54  LDD1869 
Small ribosomal subunit protein bS16m (MRPS16) LDTP13981 10.06  LDD1869 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 5.17  LDD1869 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 5.82  LDD1869 
Small ubiquitin-related modifier 2 (SUMO2) LDTP04945 7.06  LDD1869 
Spartin (SPART) LDTP08735 4.96  LDD1869 
Src substrate cortactin (CTTN) LDTP06094 5.98  LDD1869 
Survival motor neuron protein (SMN1; SMN2) LDTP06587 7.41  LDD1869 
Syntaxin-10 (STX10) LDTP00986 6.82  LDD1869 
Syntaxin-18 (STX18) LDTP13086 13.09  LDD1869 
Testis-expressed protein 264 (TEX264) LDTP14259 5.39  LDD1869 
Tetraspanin-6 (TSPAN6) LDTP14458 7.89  LDD1869 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 7.31  LDD1869 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 5.70  LDD1869 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 14.93  LDD1869 
Thyroid hormone receptor-associated protein 3 (THRAP3) LDTP13919 5.58  LDD1869 
Transforming acidic coiled-coil-containing protein 3 (TACC3) LDTP14228 5.46  LDD1869 
Translation initiation factor eIF2B subunit epsilon (EIF2B5) LDTP05765 5.54  LDD1869 
Translation initiation factor eIF2B subunit gamma (EIF2B3) LDTP12476 6.96  LDD1869 
Treacle protein (TCOF1) LDTP05867 7.67  LDD1869 
Tumor protein D54 (TPD52L2) LDTP00759 13.83  LDD1869 
U1 small nuclear ribonucleoprotein 70 kDa (SNRNP70) LDTP02292 5.43  LDD1869 
U1 small nuclear ribonucleoprotein C (SNRPC) LDTP02335 10.13  LDD1869 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 14.62  LDD1869 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 99.73  LDD1869 
Vesicle-trafficking protein SEC22b (SEC22B) LDTP01206 7.31  LDD1869 
Vimentin (VIM) LDTP02297 5.39  LDD1869 
WASH complex subunit 5 (WASHC5) LDTP05641 6.15  LDD1869 
YTH domain-containing family protein 3 (YTHDF3) LDTP08136 6.45  LDD1869 
Zinc finger CCCH domain-containing protein 18 (ZC3H18) LDTP08292 12.73  LDD1869 
Zinc finger RNA-binding protein (ZFR) LDTP15762 5.70  LDD1869 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1869 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587