Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0570
Competitor Name
Fragment8
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 397.882
Lipid-water partition coefficient (xlogp) 3.86229
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C22H22ClN2O3
Canonical SMILES
COc1cc2c(cc1OC)CN(C(=O)CCl)CC2.[c]1ccc2ccccc2n1
InChI
InChI=1S/C13H16ClNO3.C9H6N/c1-17-11-5-9-3-4-15(13(16)7-14)8-10(9)6-12(11)18-2;1-2-6-9-8(4-1)5-3-7-10-9/h5-6H,3-4,7-8H2,1-2H3;1-6H
InChIKey
KFCPIQXZMOZEDT-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
IA-alkyne
 Probe Info  		100 uM Human breast adenocarcinoma cell lysate (MDA-MB-231) [1]

Target(s) List of this Competitor

144 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 2.52; 1.02  LDD1385 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 1.45  LDD1385 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 4.25  LDD1385 
3-ketoacyl-CoA thiolase, mitochondrial (ACAA2) LDTP03998 14.30  LDD1385 
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) LDTP02329 0.54  LDD1385 
5'-nucleotidase domain-containing protein 1 (NT5DC1) LDTP17247 20.00  LDD1385 
6-phosphogluconolactonase (PGLS) LDTP14535 1.64  LDD1385 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 2.24  LDD1385 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 1.77; 2.67; 1.38 ...  LDD1385 
Aconitate hydratase, mitochondrial (ACO2) LDTP10982 1.01  LDD1385 
Acylamino-acid-releasing enzyme (APEH) LDTP02693 1.15  LDD1386 
Adenosine 5'-monophosphoramidase HINT1 (HINT1) LDTP04306 20.00  LDD1385 
Adenosine kinase (ADK) LDTP04689 0.97  LDD1385 
ADP-ribose glycohydrolase MACROD1 (MACROD1) LDTP11059 5.03  LDD1462 
ADP-ribosylation factor-like protein 3 (ARL3) LDTP03806 0.87  LDD1386 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 1.54  LDD1462 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 1.28  LDD1385 
Alpha-adducin (ADD1) LDTP03770 2.42  LDD1462 
Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) LDTP04253 0.89  LDD1385 
AMP deaminase 2 (AMPD2) LDTP05289 12.05  LDD1385 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 3.18  LDD1385 
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) LDTP05314 1.15; 5.53  LDD1385 
ATPase WRNIP1 (WRNIP1) LDTP10801 11.11  LDD1385 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 1.66  LDD1385 
Bleomycin hydrolase (BLMH) LDTP05992 1.48  LDD1386 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 5.75; 3.86  LDD1385 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 3.26  LDD1385 
Caspase-8 (CASP8) LDTP06211 1.39  LDD1386 
Cathepsin B (CTSB) LDTP02223 2.11; 3.88  LDD1385 
Cathepsin D (CTSD) LDTP02198 6.19  LDD1385 
Cathepsin Z (CTSZ) LDTP13147 3.12  LDD1385 
Cell cycle checkpoint control protein RAD9A (RAD9A) LDTP10929 1.32  LDD1385 
Cleavage and polyadenylation specificity factor subunit 3 (CPSF3) LDTP13449 12.73  LDD1385 
Cyclin-dependent kinase 19 (CDK19) LDTP11340 1.04  LDD1385 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 3.72  LDD1386 
Cyclin-dependent kinase inhibitor 3 (CDKN3) LDTP06603 1.77  LDD1386 
Cytidine deaminase (CDA) LDTP03642 12.09  LDD1385 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 19.83  LDD1386 
Deoxycytidine kinase (DCK) LDTP03400 1.83; 1.04  LDD1385 
Desumoylating isopeptidase 1 (DESI1) LDTP07407 20.00  LDD1462 
DNA repair protein RAD50 (RAD50) LDTP09912 2.72; 3.35; 4.53  LDD1385 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 3.46  LDD1462 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 2.06  LDD1385 
Double-stranded RNA-specific adenosine deaminase (ADAR) LDTP04690 3.65  LDD1385 
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) LDTP04103 1.30  LDD1385 
Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4) LDTP04077 20.00  LDD1385 
Dual specificity protein phosphatase 12 (DUSP12) LDTP13663 1.45  LDD1385 
Dynamin-1-like protein (DNM1L) LDTP00273 3.20  LDD1385 
Dynamin-2 (DNM2) LDTP04374 0.98  LDD1385 
E3 ubiquitin-protein ligase UBR5 (UBR5) LDTP01495 1.33  LDD1386 
Elongation factor 2 (EEF2) LDTP02672 2.12; 1.38  LDD1385 
Elongation factor G, mitochondrial (GFM1) LDTP10774 1.85  LDD1386 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 2.25  LDD1385 
Enoyl-CoA delta isomerase 2 (ECI2) LDTP01245 1.71  LDD1385 
ERO1-like protein alpha (ERO1A) LDTP10386 2.06; 1.90; 1.84  LDD1385 
Ethylmalonyl-CoA decarboxylase (ECHDC1) LDTP16095 1.96  LDD1462 
Eukaryotic translation initiation factor 3 subunit F (EIF3F) LDTP00246 1.46  LDD1385 
Galactokinase (GALK1) LDTP04424 1.17  LDD1386 
General transcription and DNA repair factor IIH helicase subunit XPB (ERCC3) LDTP03000 5.94  LDD1385 
Glutaredoxin-1 (GLRX) LDTP03786 12.43  LDD1385 
Glutaredoxin-related protein 5, mitochondrial (GLRX5) LDTP08181 0.92  LDD1385 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 19.94  LDD1385 
Glutathione S-transferase P (GSTP1) LDTP02333 2.61  LDD1385 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 1.09  LDD1385 
Glycerol-3-phosphate phosphatase (PGP) LDTP00089 1.45  LDD1385 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 16.59  LDD1385 
GMP reductase 2 (GMPR2) LDTP13080 1.47  LDD1385 
Haloacid dehalogenase-like hydrolase domain-containing 5 (HDHD5) LDTP18330 3.16  LDD1462 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 2.96  LDD1385 
Integrin-linked protein kinase (ILK) LDTP05859 4.37  LDD1385 
Isoamyl acetate-hydrolyzing esterase 1 homolog (IAH1) LDTP17082 2.08  LDD1385 
Isochorismatase domain-containing protein 2 (ISOC2) LDTP18123 4.70  LDD1462 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 12.38  LDD1385 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 1.29  LDD1385 
Ketosamine-3-kinase (FN3KRP) LDTP16025 20.00  LDD1385 
Lysine-specific demethylase 4B (KDM4B) LDTP01470 20.00  LDD1385 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 20.00  LDD1462 
Mannose-1-phosphate guanyltransferase alpha (GMPPA) LDTP10418 2.77  LDD1385 
Medium-chain acyl-CoA ligase ACSF2, mitochondrial (ACSF2) LDTP10177 11.02  LDD1385 
Methionine-R-sulfoxide reductase B2, mitochondrial (MSRB2) LDTP13980 20.00  LDD1462 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 3.91  LDD1462 
Mitochondrial coenzyme A diphosphatase NUDT8 (NUDT8) LDTP09598 4.11  LDD1385 
Mitogen-activated protein kinase 9 (MAPK9) LDTP04076 2.48  LDD1386 
Mitogen-activated protein kinase kinase kinase 20 (MAP3K20) LDTP12837 1.44  LDD1462 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 20.00  LDD1385 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 2.17  LDD1385 
Multifunctional protein CAD (CAD) LDTP03401 20.00  LDD1462 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 1.07; 0.84  LDD1385 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 20.00  LDD1385 
Omega-amidase NIT2 (NIT2) LDTP12428 20.00  LDD1386 
Parkinson disease protein 7 (PARK7) LDTP10878 20.00  LDD1385 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 1.82  LDD1385 
Peripheral plasma membrane protein CASK (CASK) LDTP00482 1.53  LDD1385 
Peroxiredoxin-4 (PRDX4) LDTP05773 2.84  LDD1385 
Peroxiredoxin-5, mitochondrial (PRDX5) LDTP03512 1.12  LDD1385 
Persulfide dioxygenase ETHE1, mitochondrial (ETHE1) LDTP01633 1.97  LDD1385 
Pre-rRNA-processing protein TSR1 homolog (TSR1) LDTP14888 1.48  LDD1385 
Probable aminopeptidase NPEPL1 (NPEPL1) LDTP09126 20.00  LDD1462 
Probable ATP-dependent RNA helicase DDX59 (DDX59) LDTP07098 20.00  LDD1385 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) LDTP05373 2.58  LDD1385 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 1.01  LDD1385 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 1.19  LDD1385 
Protein disulfide-isomerase (P4HB) LDTP02188 1.91  LDD1385 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 12.79  LDD1385 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 12.39; 12.79  LDD1385 
Protein disulfide-isomerase A6 (PDIA6) LDTP06314 4.67  LDD1385 
Protein PML (PML) LDTP03496 2.08  LDD1385 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 0.72  LDD1462 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 0.94  LDD1385 
Putative transferase CAF17, mitochondrial (IBA57) LDTP07110 1.50  LDD1386 
Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) LDTP03644 1.14  LDD1385 
Pyruvate carboxylase, mitochondrial (PC) LDTP02576 0.85  LDD1385 
Pyruvate kinase PKM (PKM) LDTP02733 0.95  LDD1385 
Ras-related GTP-binding protein C (RRAGC) LDTP12166 5.14  LDD1385 
Ribonuclease H2 subunit C (RNASEH2C) LDTP09446 20.00  LDD1385 
Serine--tRNA ligase, cytoplasmic (SARS1) LDTP04265 1.12  LDD1385 
Serine/threonine-protein kinase MRCK beta (CDC42BPB) LDTP14155 20.00  LDD1385 
Serine/threonine-protein kinase Nek9 (NEK9) LDTP09412 20.00  LDD1386 
Serine/threonine-protein kinase VRK1 (VRK1) LDTP11030 2.02  LDD1385 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) LDTP06199 2.20  LDD1385 
Serine/threonine-protein phosphatase CPPED1 (CPPED1) LDTP11107 1.80  LDD1385 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 2.40  LDD1385 
Sterol carrier protein 2 (SCP2) LDTP03163 20.00  LDD1385 
Succinate-semialdehyde dehydrogenase, mitochondrial (ALDH5A1) LDTP04438 2.71  LDD1462 
Thioredoxin (TXN) LDTP02502 2.45  LDD1385 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 1.73; 2.55  LDD1385 
Thioredoxin, mitochondrial (TXN2) LDTP10973 4.46  LDD1462 
Threonine synthase-like 1 (THNSL1) LDTP19669 20.00  LDD1462 
Thymidine kinase, cytosolic (TK1) LDTP02022 2.37; 5.67  LDD1385 
Thymidylate kinase (DTYMK) LDTP03258 0.60; 0.41  LDD1462 
Transmembrane protease serine 12 (TMPRSS12) LDTP15306 1.00  LDD1385 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 1.95; 2.08; 1.51  LDD1385 
Tubulin alpha-4A chain (TUBA4A) LDTP05075 1.77; 1.84; 1.40  LDD1385 
Tudor-interacting repair regulator protein (NUDT16L1) LDTP11111 2.14  LDD1386 
Ubiquitin carboxyl-terminal hydrolase 16 (USP16) LDTP14159 20.00  LDD1386 
Ubiquitin carboxyl-terminal hydrolase 28 (USP28) LDTP10785 1.15  LDD1462 
Ubiquitin carboxyl-terminal hydrolase 7 (USP7) LDTP09962 20.00  LDD1462 
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) LDTP05070 1.38  LDD1385 
Ubiquitin-conjugating enzyme E2 S (UBE2S) LDTP06621 1.07  LDD1386 
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT) LDTP00601 2.41  LDD1462 
Uridine phosphorylase 1 (UPP1) LDTP06643 18.70  LDD1385 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 20.00  LDD1462 
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (PDK1) LDTP06320 20.00  LDD1462 
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP1) LDTP12960 20.00  LDD1385 
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⏷ Show the Full List of 144 Enzyme
21 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Apoptotic chromatin condensation inducer in the nucleus (ACIN1) LDTP13490 3.85  LDD1385 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 2.16  LDD1385 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 2.96  LDD1385 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 3.50  LDD1385 
Chloride intracellular channel protein 6 (CLIC6) LDTP10642 5.09  LDD1462 
Exportin-1 (XPO1) LDTP00501 2.36; 1.81  LDD1385 
Exportin-2 (CSE1L) LDTP04662 1.21  LDD1385 
Gasdermin-D (GSDMD) LDTP04801 2.60  LDD1386 
Importin-7 (IPO7) LDTP01574 1.33  LDD1385 
Nuclear cap-binding protein subunit 1 (NCBP1) LDTP05591 1.95  LDD1462 
Nuclear pore complex protein Nup214 (NUP214) LDTP03777 1.70  LDD1385 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 4.30  LDD1386 
Nucleoporin NUP35 (NUP35) LDTP09204 2.25  LDD1385 
Protein SEC13 homolog (SEC13) LDTP04707 1.86  LDD1385 
Signal recognition particle 9 kDa protein (SRP9) LDTP04259 1.01  LDD1385 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 0.87  LDD1385 
Sorting nexin-6 (SNX6) LDTP13661 1.43  LDD1385 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 2.26  LDD1385 
THO complex subunit 6 homolog (THOC6) LDTP08315 12.32  LDD1385 
Unconventional myosin-Ic (MYO1C) LDTP00196 5.38  LDD1385 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 6.17  LDD1462 
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⏷ Show the Full List of 21 Transporter and channel
10 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
CDKN2A-interacting protein (CDKN2AIP) LDTP12792 3.97  LDD1385 
Chromatin accessibility complex protein 1 (CHRAC1) LDTP12507 1.27  LDD1386 
COUP transcription factor 2 (NR2F2) LDTP03280 20.00  LDD1462 
eIF5-mimic protein 2 (BZW1) LDTP07940 1.02  LDD1385 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 17.29  LDD1385 
Nucleus accumbens-associated protein 1 (NACC1) LDTP10756 2.80  LDD1385 
Recombining binding protein suppressor of hairless (RBPJ) LDTP05485 1.30  LDD1385 
Signal transducer and activator of transcription 1-alpha/beta (STAT1) LDTP03969 9.04  LDD1385 
SWI/SNF complex subunit SMARCC2 (SMARCC2) LDTP09311 3.12  LDD1385 
Zinc finger protein 217 (ZNF217) LDTP01191 1.75  LDD1385 
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⏷ Show the Full List of 10 Transcription factor
123 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
A-kinase anchor protein 8-like (AKAP8L) LDTP13591 1.79  LDD1386 
Actin-related protein 2/3 complex subunit 3 (ARPC3) LDTP00552 1.28  LDD1385 
Actin-related protein 3 (ACTR3) LDTP04902 0.94  LDD1385 
AH receptor-interacting protein (AIP) LDTP00202 1.31  LDD1386 
Alpha-actinin-1 (ACTN1) LDTP02631 0.95  LDD1385 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 3.09  LDD1385 
Anillin (ANLN) LDTP12443 3.84  LDD1385 
Ankyrin repeat and KH domain-containing protein 1 (ANKHD1) LDTP08573 20.00  LDD1385 
Ashwin (C2orf49) LDTP15896 4.51  LDD1462 
Ataxin-7-like protein 3B (ATXN7L3B) LDTP15730 1.89  LDD1385 
BRISC and BRCA1-A complex member 1 (BABAM1) LDTP12737 1.27  LDD1385 
Calponin-2 (CNN2) LDTP10864 3.61; 3.32  LDD1385 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 3.53  LDD1385 
Cleavage stimulation factor subunit 2 (CSTF2) LDTP03665 1.50  LDD1385 
Cleavage stimulation factor subunit 2 tau variant (CSTF2T) LDTP11718 1.51  LDD1386 
Cofilin-1 (CFL1) LDTP03244 0.94  LDD1385 
Condensin complex subunit 1 (NCAPD2) LDTP06281 15.32  LDD1385 
Condensin complex subunit 2 (NCAPH) LDTP06268 4.42  LDD1385 
Coronin-1C (CORO1C) LDTP13580 2.35; 1.02  LDD1385 
Crk-like protein (CRKL) LDTP04092 16.18  LDD1385 
Cyclin-H (CCNH) LDTP04487 0.84  LDD1385 
Cysteine and glycine-rich protein 2 (CSRP2) LDTP06542 2.42  LDD1385 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 0.94  LDD1385 
Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) LDTP14250 4.05  LDD1462 
Cytosolic Fe-S cluster assembly factor NUBP1 (NUBP1) LDTP04560 0.59  LDD1462 
Cytosolic iron-sulfur assembly component 2B (CIAO2B) LDTP13979 1.63  LDD1386 
Dedicator of cytokinesis protein 7 (DOCK7) LDTP10613 3.50  LDD1385 
Disks large-associated protein 5 (DLGAP5) LDTP06378 4.68  LDD1385 
Dynactin subunit 1 (DCTN1) LDTP06082 1.58  LDD1385 
Dynactin subunit 4 (DCTN4) LDTP13402 20.00  LDD1462 
EF-hand domain-containing protein D2 (EFHD2) LDTP15701 20.00  LDD1385 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 2.26  LDD1386 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 2.98  LDD1385 
Eukaryotic translation initiation factor 3 subunit M (EIF3M) LDTP07947 1.39  LDD1385 
FH1/FH2 domain-containing protein 1 (FHOD1) LDTP14195 5.27  LDD1386 
Formin-binding protein 1-like (FNBP1L) LDTP07088 3.55  LDD1462 
GrpE protein homolog 1, mitochondrial (GRPEL1) LDTP12144 0.99  LDD1386 
H/ACA ribonucleoprotein complex subunit 2 (NHP2) LDTP12754 3.04  LDD1386 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.81  LDD1385 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 2.75; 0.88  LDD1385 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 5.28  LDD1462 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 4.16  LDD1462 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 1.06  LDD1385 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 2.19  LDD1385 
Hippocalcin-like protein 1 (HPCAL1) LDTP03841 2.67  LDD1385 
Hsp70-binding protein 1 (HSPBP1) LDTP12914 1.58  LDD1386 
Integrator complex subunit 13 (INTS13) LDTP12685 1.52  LDD1385 
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) LDTP00463 2.54  LDD1385 
Inverted formin-2 (INF2) LDTP06681 20.00  LDD1385 
KH domain-containing RNA-binding protein QKI (QKI) LDTP10700 1.20  LDD1385 
Kinectin (KTN1) LDTP08238 1.69  LDD1385 
Kinetochore protein NDC80 homolog (NDC80) LDTP00431 1.44  LDD1385 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 2.38; 3.91; 2.00 ...  LDD1385 
LanC-like protein 2 (LANCL2) LDTP12571 1.28  LDD1385 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 2.14; 1.32  LDD1385 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 1.76  LDD1385 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 2.58  LDD1385 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 2.31  LDD1385 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 2.23  LDD1385 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 2.58  LDD1385 
LIM and calponin homology domains-containing protein 1 (LIMCH1) LDTP13705 20.00  LDD1462 
Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) LDTP14217 20.00  LDD1462 
MAD2L1-binding protein (MAD2L1BP) LDTP06276 5.36  LDD1462 
Mediator of RNA polymerase II transcription subunit 15 (MED15) LDTP10771 3.83; 3.31  LDD1385 
Mediator of RNA polymerase II transcription subunit 17 (MED17) LDTP12669 1.57  LDD1385 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 7.05  LDD1385 
MMS19 nucleotide excision repair protein homolog (MMS19) LDTP10843 1.96  LDD1385 
MOB-like protein phocein (MOB4) LDTP13964 1.29  LDD1385 
Multivesicular body subunit 12A (MVB12A) LDTP10284 1.57  LDD1386 
Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 1.99  LDD1385 
Nuclear migration protein nudC (NUDC) LDTP13817 1.16  LDD1385 
Nuclear mitotic apparatus protein 1 (NUMA1) LDTP06244 13.73  LDD1385 
Nucleolar protein 58 (NOP58) LDTP13925 2.60  LDD1385 
NudC domain-containing protein 1 (NUDCD1) LDTP10781 2.71  LDD1385 
Plastin-3 (PLS3) LDTP02692 1.54  LDD1385 
Plectin (PLEC) LDTP06330 1.38; 1.77  LDD1385 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 0.86; 3.33  LDD1385 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 1.58  LDD1385 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 2.57  LDD1385 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 2.02  LDD1385 
Proteasome activator complex subunit 4 (PSME4) LDTP06250 2.08  LDD1385 
Protein diaphanous homolog 1 (DIAPH1) LDTP01011 1.48  LDD1385 
Protein KRI1 homolog (KRI1) LDTP17765 5.25  LDD1462 
Protein misato homolog 1 (MSTO1) LDTP11239 1.44  LDD1385 
Protein PAXX (PAXX) LDTP11235 1.49  LDD1385 
Protein S100-A11 (S100A11) LDTP03620 1.03  LDD1385 
Protein strawberry notch homolog 1 (SBNO1) LDTP14337 1.47  LDD1386 
Protein transport protein Sec24C (SEC24C) LDTP04594 5.36  LDD1462 
Protein unc-45 homolog A (UNC45A) LDTP11890 1.13  LDD1386 
RAB7A-interacting MON1-CCZ1 complex subunit 1 (RIMOC1) LDTP14351 2.45  LDD1385 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 13.23  LDD1385 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 2.72  LDD1462 
Reticulon-4 (RTN4) LDTP12412 1.54  LDD1385 
Serpin H1 (SERPINH1) LDTP04363 4.16  LDD1385 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 0.86  LDD1385 
Small ribosomal subunit protein eS27 (RPS27) LDTP03987 3.07  LDD1385 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 1.33  LDD1385 
Small ribosomal subunit protein mS40 (MRPS18B) LDTP14215 0.98  LDD1462 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 1.35  LDD1385 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 3.90; 1.53  LDD1385 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 1.94  LDD1385 
SNW domain-containing protein 1 (SNW1) LDTP05930 2.66  LDD1385 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 1.34  LDD1385 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 1.59  LDD1385 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 1.08  LDD1385 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 1.29  LDD1385 
T-complex protein 1 subunit eta (CCT7) LDTP10990 1.90  LDD1385 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.98  LDD1385 
Targeting protein for Xklp2 (TPX2) LDTP13583 12.37  LDD1385 
TBC1 domain family member 23 (TBC1D23) LDTP12651 1.79  LDD1385 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 1.80  LDD1385 
Trafficking protein particle complex subunit 4 (TRAPPC4) LDTP13837 1.42  LDD1386 
Transcription elongation regulator 1 (TCERG1) LDTP00430 0.80  LDD1385 
Transcription initiation factor IIA subunit 2 (GTF2A2) LDTP04517 1.02  LDD1386 
Treacle protein (TCOF1) LDTP05867 1.99; 2.52  LDD1385 
Tropomodulin-3 (TMOD3) LDTP18494 1.54  LDD1385 
Tubulin beta chain (TUBB) LDTP02205 1.42; 1.84  LDD1385 
U4/U6.U5 tri-snRNP-associated protein 1 (SART1) LDTP00727 3.70  LDD1385 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 4.24  LDD1462 
WD repeat domain phosphoinositide-interacting protein 3 (WDR45B) LDTP07037 20.00  LDD1462 
WW domain-containing adapter protein with coiled-coil (WAC) LDTP11191 2.19  LDD1385 
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) LDTP08018 5.11  LDD1462 
ZW10 interactor (ZWINT) LDTP01532 1.25  LDD1386 
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⏷ Show the Full List of 123 Other

Full Information of The Labelling Profiles of This Competitor

IA-alkyne
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 100 uM
Quantitative Method Isotope tag
Competitor Name Fragment8
Competitor Concentration 500 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cell lysate (MDA-MB-231)
Interaction Atlas ID  LDD1385  Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 100 uM
Quantitative Method Isotope tag
Competitor Name Fragment8
Competitor Concentration 500 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Lymph node
Disease Model Burkitt lymphoma [ICD-11:2A85]
Model Name Human burkitt lymphoma cell lysate (Ramos)
Interaction Atlas ID  LDD1386  Download The Altas
  
Experiment 3 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 100 uM
Quantitative Method Isotope tag
Competitor Name Fragment8
Competitor Concentration 200 uM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cells (MDA-MB-231)
Interaction Atlas ID  LDD1462  Download The Altas

References

1 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.