Details of the Target

General Information of Target

Target ID LDTP06378
Target Name Disks large-associated protein 5 (DLGAP5)
Gene Name DLGAP5
Gene ID 9787
Synonyms
DLG7; KIAA0008; Disks large-associated protein 5; DAP-5; Discs large homolog 7; Disks large-associated protein DLG7; Hepatoma up-regulated protein; HURP
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSSSHFASRHRKDISTEMIRTKIAHRKSLSQKENRHKEYERNRHFGLKDVNIPTLEGRIL
VELDETSQGLVPEKTNVKPRAMKTILGDQRKQMLQKYKEEKQLQKLKEQREKAKRGIFKV
GRYRPDMPCFLLSNQNAVKAEPKKAIPSSVRITRSKAKDQMEQTKIDNESDVRAIRPGPR
QTSEKKVSDKEKKVVQPVMPTSLRMTRSATQAAKQVPRTVSSTTARKPVTRAANENEPEG
KVPSKGRPAKNVETKPDKGISCKVDSEENTLNSQTNATSGMNPDGVLSKMENLPEINTAK
IKGKNSFAPKDFMFQPLDGLKTYQVTPMTPRSANAFLTPSYTWTPLKTEVDESQATKEIL
AQKCKTYSTKTIQQDSNKLPCPLGPLTVWHEEHVLNKNEATTKNLNGLPIKEVPSLERNE
GRIAQPHHGVPYFRNILQSETEKLTSHCFEWDRKLELDIPDDAKDLIRTAVGQTRLLMKE
RFKQFEGLVDDCEYKRGIKETTCTDLDGFWDMVSFQIEDVIHKFNNLIKLEESGWQVNNN
MNHNMNKNVFRKKVVSGIASKPKQDDAGRIAARNRLAAIKNAMRERIRQEECAETAVSVI
PKEVDKIVFDAGFFRVESPVKLFSGLSVSSEGPSQRLGTPKSVNKAVSQSRNEMGIPQQT
TSPENAGPQNTKSEHVKKTLFLSIPESRSSIEDAQCPGLPDLIEENHVVNKTDLKVDCLS
SERMSLPLLAGGVADDINTNKKEGISDVVEGMELNSSITSQDVLMSSPEKNTASQNSILE
EGETKISQSELFDNKSLTTECHLLDSPGLNCSNPFTQLERRHQEHARHISFGGNLITFSP
LQPGEF
Target Bioclass
Other
Family
SAPAP family
Subcellular location
Nucleus
Function
Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Uniprot ID
Q15398
Ensemble ID
ENST00000247191.7
HGNC ID
HGNC:16864

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 25 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
CY-1
 Probe Info  		100.00  LDD0243  [2]
STPyne
 Probe Info  		K119(10.00); K48(4.04); K678(9.79)  LDD0277  [3]
P12
 Probe Info  		15.56  LDD0202  [4]
BTD
 Probe Info  		C364(1.40); C592(1.12)  LDD2090  [5]
Sulforaphane-probe2
 Probe Info  		2.08  LDD0160  [6]
DA-P3
 Probe Info  		4.31  LDD0179  [7]
AHL-Pu-1
 Probe Info  		C811(2.65); C801(2.41); C381(2.52); C696(5.49)  LDD0168  [8]
HHS-475
 Probe Info  		Y341(0.75)  LDD0264  [9]
DBIA
 Probe Info  		C801(1.15); C811(1.15); C381(1.03); C129(0.98)  LDD0078  [10]
ATP probe
 Probe Info  		N.A.  LDD0199  [11]
4-Iodoacetamidophenylacetylene
 Probe Info  		C503(0.00); C448(0.00); C718(0.00); C129(0.00)  LDD0038  [12]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [13]
Lodoacetamide azide
 Probe Info  		C503(0.00); C129(0.00); C718(0.00); C592(0.00)  LDD0037  [12]
NAIA_4
 Probe Info  		C129(0.00); C448(0.00); C592(0.00); C696(0.00)  LDD2226  [14]
Compound 10
 Probe Info  		C129(0.00); C381(0.00); C696(0.00)  LDD2216  [15]
Compound 11
 Probe Info  		N.A.  LDD2213  [15]
IPM
 Probe Info  		C696(0.00); C129(0.00)  LDD0005  [16]
TFBX
 Probe Info  		N.A.  LDD0148  [17]
VSF
 Probe Info  		N.A.  LDD0007  [16]
Phosphinate-6
 Probe Info  		C696(0.00); C364(0.00); C592(0.00); C262(0.00)  LDD0018  [18]
Acrolein
 Probe Info  		C718(0.00); C592(0.00)  LDD0217  [19]
Methacrolein
 Probe Info  		N.A.  LDD0218  [19]
AOyne
 Probe Info  		15.00  LDD0443  [20]
NAIA_5
 Probe Info  		C492(0.00); C503(0.00); C592(0.00); C381(0.00)  LDD2223  [14]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe13
 Probe Info  		16.23  LDD0476  [21]
FFF probe3
 Probe Info  		20.00  LDD0465  [21]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C811(2.65); C801(2.41); C381(2.52); C696(5.49)  LDD0168  [8]
 LDCM0026  4SU-RNA+native RNA HEK-293T C811(3.12); C381(2.51); C696(6.17); C592(2.07)  LDD0169  [8]
 LDCM0214  AC1 HCT 116 C129(0.87); C448(1.03); C718(1.31); C801(1.28)  LDD0531  [10]
 LDCM0215  AC10 HCT 116 C129(0.97); C448(0.81); C718(1.02); C801(0.90)  LDD0532  [10]
 LDCM0216  AC100 HCT 116 C129(1.16); C448(0.95); C718(0.96); C801(0.90)  LDD0533  [10]
 LDCM0217  AC101 HCT 116 C129(1.20); C448(1.01); C718(1.00); C801(0.93)  LDD0534  [10]
 LDCM0218  AC102 HCT 116 C129(1.11); C448(1.00); C718(1.18); C801(0.98)  LDD0535  [10]
 LDCM0219  AC103 HCT 116 C129(1.52); C448(0.88); C718(1.60); C801(1.12)  LDD0536  [10]
 LDCM0220  AC104 HCT 116 C129(1.11); C448(0.98); C718(1.11); C801(1.19)  LDD0537  [10]
 LDCM0221  AC105 HCT 116 C129(1.41); C448(0.93); C718(1.24); C801(0.91)  LDD0538  [10]
 LDCM0222  AC106 HCT 116 C129(1.56); C448(0.81); C718(1.47); C801(1.01)  LDD0539  [10]
 LDCM0223  AC107 HCT 116 C129(1.03); C448(0.79); C718(1.09); C801(1.15)  LDD0540  [10]
 LDCM0224  AC108 HCT 116 C129(0.93); C448(0.88); C718(1.35); C801(1.02)  LDD0541  [10]
 LDCM0225  AC109 HCT 116 C129(0.80); C448(1.01); C718(1.39); C801(0.78)  LDD0542  [10]
 LDCM0226  AC11 HCT 116 C129(1.27); C448(0.88); C718(1.14); C801(1.41)  LDD0543  [10]
 LDCM0227  AC110 HCT 116 C129(1.09); C448(0.87); C718(1.26); C801(1.02)  LDD0544  [10]
 LDCM0228  AC111 HCT 116 C129(1.07); C448(0.83); C718(1.29); C801(0.77)  LDD0545  [10]
 LDCM0229  AC112 HCT 116 C129(0.99); C448(0.84); C718(1.21); C801(0.93)  LDD0546  [10]
 LDCM0230  AC113 HCT 116 C129(1.06); C448(1.02); C718(1.02); C801(0.81)  LDD0547  [10]
 LDCM0231  AC114 HCT 116 C129(1.13); C448(0.68); C718(1.29); C801(1.06)  LDD0548  [10]
 LDCM0232  AC115 HCT 116 C129(1.32); C448(0.74); C718(1.40); C801(1.24)  LDD0549  [10]
 LDCM0233  AC116 HCT 116 C129(1.34); C448(0.68); C718(1.13); C801(1.22)  LDD0550  [10]
 LDCM0234  AC117 HCT 116 C129(1.26); C448(0.81); C718(1.43); C801(1.03)  LDD0551  [10]
 LDCM0235  AC118 HCT 116 C129(1.08); C448(0.78); C718(1.18); C801(0.96)  LDD0552  [10]
 LDCM0236  AC119 HCT 116 C129(1.16); C448(0.78); C718(1.39); C801(1.04)  LDD0553  [10]
 LDCM0237  AC12 HCT 116 C129(0.93); C448(1.12); C718(0.96); C801(1.04)  LDD0554  [10]
 LDCM0238  AC120 HCT 116 C129(1.37); C448(0.79); C718(1.11); C801(1.11)  LDD0555  [10]
 LDCM0239  AC121 HCT 116 C129(1.14); C448(0.98); C718(1.17); C801(1.02)  LDD0556  [10]
 LDCM0240  AC122 HCT 116 C129(0.99); C448(1.08); C718(1.21); C801(1.06)  LDD0557  [10]
 LDCM0241  AC123 HCT 116 C129(1.02); C448(1.03); C718(1.40); C801(1.20)  LDD0558  [10]
 LDCM0242  AC124 HCT 116 C129(1.24); C448(0.99); C718(1.30); C801(1.19)  LDD0559  [10]
 LDCM0243  AC125 HCT 116 C129(1.16); C448(0.82); C718(1.14); C801(0.98)  LDD0560  [10]
 LDCM0244  AC126 HCT 116 C129(1.57); C448(0.80); C718(1.31); C801(1.18)  LDD0561  [10]
 LDCM0245  AC127 HCT 116 C129(1.75); C448(0.76); C718(1.49); C801(1.22)  LDD0562  [10]
 LDCM0246  AC128 HCT 116 C129(0.79); C448(1.14); C718(1.25)  LDD0563  [10]
 LDCM0247  AC129 HCT 116 C129(0.41); C448(1.20); C718(0.98)  LDD0564  [10]
 LDCM0249  AC130 HCT 116 C129(0.74); C448(1.12); C718(1.10)  LDD0566  [10]
 LDCM0250  AC131 HCT 116 C129(0.56); C448(0.95); C718(0.93)  LDD0567  [10]
 LDCM0251  AC132 HCT 116 C129(0.44); C448(0.82); C718(0.86)  LDD0568  [10]
 LDCM0252  AC133 HCT 116 C129(0.52); C448(0.91); C718(1.25)  LDD0569  [10]
 LDCM0253  AC134 HCT 116 C129(0.66); C448(0.98); C718(1.32)  LDD0570  [10]
 LDCM0254  AC135 HCT 116 C129(0.55); C448(0.96); C718(1.30)  LDD0571  [10]
 LDCM0255  AC136 HCT 116 C129(0.53); C448(0.80); C718(1.09)  LDD0572  [10]
 LDCM0256  AC137 HCT 116 C129(0.49); C448(0.98); C718(0.90)  LDD0573  [10]
 LDCM0257  AC138 HCT 116 C129(0.57); C448(0.91); C718(1.04)  LDD0574  [10]
 LDCM0258  AC139 HCT 116 C129(0.58); C448(0.97); C718(1.08)  LDD0575  [10]
 LDCM0259  AC14 HCT 116 C129(0.76); C448(0.92); C718(1.02); C801(1.29)  LDD0576  [10]
 LDCM0260  AC140 HCT 116 C129(0.57); C448(0.82); C718(1.23)  LDD0577  [10]
 LDCM0261  AC141 HCT 116 C129(0.58); C448(0.89); C718(1.17)  LDD0578  [10]
 LDCM0262  AC142 HCT 116 C129(0.51); C448(0.84); C718(0.82)  LDD0579  [10]
 LDCM0263  AC143 HCT 116 C129(1.13); C448(0.80); C718(1.01); C801(1.03)  LDD0580  [10]
 LDCM0264  AC144 HCT 116 C448(0.43); C811(1.14); C801(1.22); C129(1.33)  LDD0581  [10]
 LDCM0265  AC145 HCT 116 C718(1.03); C448(1.10); C811(1.17); C129(1.19)  LDD0582  [10]
 LDCM0266  AC146 HCT 116 C718(1.07); C448(1.23); C801(1.24); C811(1.27)  LDD0583  [10]
 LDCM0267  AC147 HCT 116 C448(0.93); C801(1.30); C129(1.30); C718(1.36)  LDD0584  [10]
 LDCM0268  AC148 HCT 116 C811(1.39); C801(1.46); C448(1.49); C718(1.62)  LDD0585  [10]
 LDCM0269  AC149 HCT 116 C811(1.35); C801(1.39); C448(1.43); C718(1.56)  LDD0586  [10]
 LDCM0270  AC15 HCT 116 C448(0.88); C129(1.03); C718(1.19); C801(1.33)  LDD0587  [10]
 LDCM0271  AC150 HCT 116 C718(1.01); C129(1.13); C801(1.16); C448(1.22)  LDD0588  [10]
 LDCM0272  AC151 HCT 116 C801(1.00); C718(1.05); C448(1.07); C129(1.09)  LDD0589  [10]
 LDCM0273  AC152 HCT 116 C448(1.03); C801(1.28); C718(1.30); C811(1.36)  LDD0590  [10]
 LDCM0274  AC153 HCT 116 C448(1.48); C801(1.80); C811(1.81); C718(2.04)  LDD0591  [10]
 LDCM0621  AC154 HCT 116 C129(1.22); C448(1.14); C718(1.16); C801(1.45)  LDD2158  [10]
 LDCM0622  AC155 HCT 116 C129(1.43); C448(1.25); C718(1.35); C801(1.67)  LDD2159  [10]
 LDCM0623  AC156 HCT 116 C129(1.15); C448(1.26); C718(1.08); C801(1.29)  LDD2160  [10]
 LDCM0624  AC157 HCT 116 C129(0.97); C448(1.40); C718(1.00); C801(1.32)  LDD2161  [10]
 LDCM0276  AC17 HCT 116 C129(0.98); C801(1.06); C811(1.06); C718(1.06)  LDD0593  [10]
 LDCM0277  AC18 HCT 116 C448(0.82); C129(0.95); C801(1.11); C811(1.11)  LDD0594  [10]
 LDCM0278  AC19 HCT 116 C718(1.04); C448(1.06); C129(1.08); C801(1.32)  LDD0595  [10]
 LDCM0279  AC2 HCT 116 C129(0.74); C718(1.10); C801(1.11); C811(1.11)  LDD0596  [10]
 LDCM0280  AC20 HCT 116 C448(0.95); C718(1.04); C129(1.08); C801(1.30)  LDD0597  [10]
 LDCM0281  AC21 HCT 116 C448(1.03); C801(1.43); C811(1.43); C718(1.46)  LDD0598  [10]
 LDCM0282  AC22 HCT 116 C801(1.02); C811(1.02); C448(1.11); C718(1.13)  LDD0599  [10]
 LDCM0283  AC23 HCT 116 C448(0.89); C718(0.98); C129(1.06); C801(1.27)  LDD0600  [10]
 LDCM0284  AC24 HCT 116 C129(1.03); C718(1.06); C448(1.07); C801(1.26)  LDD0601  [10]
 LDCM0285  AC25 HCT 116 C801(0.99); C811(0.99); C718(1.14); C448(1.16)  LDD0602  [10]
 LDCM0286  AC26 HCT 116 C448(1.10); C801(1.23); C811(1.23); C718(1.38)  LDD0603  [10]
 LDCM0287  AC27 HCT 116 C801(1.35); C811(1.35); C448(1.40); C718(1.43)  LDD0604  [10]
 LDCM0288  AC28 HCT 116 C448(0.98); C801(1.14); C811(1.14); C718(1.39)  LDD0605  [10]
 LDCM0289  AC29 HCT 116 C448(1.01); C801(1.18); C811(1.18); C718(1.33)  LDD0606  [10]
 LDCM0290  AC3 HCT 116 C129(0.75); C718(1.25); C801(1.26); C811(1.26)  LDD0607  [10]
 LDCM0291  AC30 HCT 116 C448(1.00); C718(1.19); C801(1.46); C811(1.46)  LDD0608  [10]
 LDCM0292  AC31 HCT 116 C448(1.20); C801(1.26); C811(1.26); C718(1.39)  LDD0609  [10]
 LDCM0293  AC32 HCT 116 C801(1.09); C811(1.09); C448(1.13); C718(1.73)  LDD0610  [10]
 LDCM0294  AC33 HCT 116 C448(0.93); C801(1.19); C811(1.19); C718(1.56)  LDD0611  [10]
 LDCM0295  AC34 HCT 116 C448(1.13); C718(1.79); C801(1.90); C811(1.90)  LDD0612  [10]
 LDCM0296  AC35 HCT 116 C801(0.69); C811(0.69); C448(1.02); C129(1.41)  LDD0613  [10]
 LDCM0297  AC36 HCT 116 C801(0.58); C811(0.58); C448(1.14); C718(1.46)  LDD0614  [10]
 LDCM0298  AC37 HCT 116 C801(0.52); C811(0.52); C448(0.95); C718(1.30)  LDD0615  [10]
 LDCM0299  AC38 HCT 116 C801(0.61); C811(0.61); C448(0.99); C718(1.79)  LDD0616  [10]
 LDCM0300  AC39 HCT 116 C801(0.82); C811(0.82); C448(1.05); C718(1.37)  LDD0617  [10]
 LDCM0301  AC4 HCT 116 C129(0.92); C801(1.08); C811(1.08); C718(1.26)  LDD0618  [10]
 LDCM0302  AC40 HCT 116 C448(0.87); C718(1.02); C801(1.32); C811(1.32)  LDD0619  [10]
 LDCM0303  AC41 HCT 116 C801(0.45); C811(0.45); C448(0.85); C718(1.62)  LDD0620  [10]
 LDCM0304  AC42 HCT 116 C448(0.75); C801(0.80); C811(0.80); C718(1.45)  LDD0621  [10]
 LDCM0305  AC43 HCT 116 C801(0.51); C811(0.51); C448(0.89); C718(1.61)  LDD0622  [10]
 LDCM0306  AC44 HCT 116 C801(0.43); C811(0.43); C448(1.02); C718(1.35)  LDD0623  [10]
 LDCM0307  AC45 HCT 116 C801(0.50); C811(0.50); C448(0.78); C718(1.49)  LDD0624  [10]
 LDCM0308  AC46 HCT 116 C718(1.06); C448(1.08); C801(1.13); C811(1.13)  LDD0625  [10]
 LDCM0309  AC47 HCT 116 C718(1.02); C801(1.04); C811(1.04); C448(1.05)  LDD0626  [10]
 LDCM0310  AC48 HCT 116 C718(0.93); C801(1.06); C811(1.06); C448(1.30)  LDD0627  [10]
 LDCM0311  AC49 HCT 116 C448(1.03); C718(1.11); C801(1.87); C811(1.87)  LDD0628  [10]
 LDCM0312  AC5 HCT 116 C129(0.72); C801(0.97); C811(0.97); C718(1.19)  LDD0629  [10]
 LDCM0313  AC50 HCT 116 C718(0.92); C448(1.06); C801(1.52); C811(1.52)  LDD0630  [10]
 LDCM0314  AC51 HCT 116 C718(0.84); C801(1.13); C811(1.13); C448(1.26)  LDD0631  [10]
 LDCM0315  AC52 HCT 116 C718(0.87); C801(1.16); C811(1.16); C448(1.21)  LDD0632  [10]
 LDCM0316  AC53 HCT 116 C718(1.14); C448(1.30); C801(1.30); C811(1.30)  LDD0633  [10]
 LDCM0317  AC54 HCT 116 C718(1.12); C801(1.12); C811(1.12); C448(1.14)  LDD0634  [10]
 LDCM0318  AC55 HCT 116 C448(1.25); C718(1.28); C801(1.63); C811(1.63)  LDD0635  [10]
 LDCM0319  AC56 HCT 116 C718(1.00); C448(1.04); C801(2.40); C811(2.40)  LDD0636  [10]
 LDCM0320  AC57 HCT 116 C129(0.71); C801(0.81); C811(0.81); C448(1.04)  LDD0637  [10]
 LDCM0321  AC58 HCT 116 C448(0.98); C801(1.07); C811(1.07); C129(1.13)  LDD0638  [10]
 LDCM0322  AC59 HCT 116 C129(0.72); C448(0.81); C801(1.14); C811(1.14)  LDD0639  [10]
 LDCM0323  AC6 HCT 116 C448(0.78); C718(0.98); C129(1.12); C801(1.14)  LDD0640  [10]
 LDCM0324  AC60 HCT 116 C448(0.74); C129(0.77); C801(1.12); C811(1.12)  LDD0641  [10]
 LDCM0325  AC61 HCT 116 C129(0.89); C801(1.10); C811(1.10); C448(1.16)  LDD0642  [10]
 LDCM0326  AC62 HCT 116 C129(0.65); C448(0.85); C801(1.11); C811(1.11)  LDD0643  [10]
 LDCM0327  AC63 HCT 116 C129(0.75); C448(0.76); C718(1.26); C801(1.48)  LDD0644  [10]
 LDCM0328  AC64 HCT 116 C129(0.67); C448(0.89); C801(1.26); C811(1.26)  LDD0645  [10]
 LDCM0329  AC65 HCT 116 C448(0.83); C129(1.00); C718(1.17); C801(1.19)  LDD0646  [10]
 LDCM0330  AC66 HCT 116 C448(0.91); C129(0.93); C718(0.98); C801(1.41)  LDD0647  [10]
 LDCM0331  AC67 HCT 116 C129(0.70); C448(0.73); C718(1.19); C801(1.67)  LDD0648  [10]
 LDCM0332  AC68 HCT 116 C801(0.95); C811(0.95); C448(1.00); C718(1.10)  LDD0649  [10]
 LDCM0333  AC69 HCT 116 C448(1.06); C718(1.09); C801(1.23); C811(1.23)  LDD0650  [10]
 LDCM0334  AC7 HCT 116 C448(0.85); C129(0.86); C801(0.89); C811(0.89)  LDD0651  [10]
 LDCM0335  AC70 HCT 116 C448(0.96); C801(1.06); C811(1.06); C718(1.15)  LDD0652  [10]
 LDCM0336  AC71 HCT 116 C801(0.88); C811(0.88); C718(0.97); C448(1.16)  LDD0653  [10]
 LDCM0337  AC72 HCT 116 C448(1.03); C801(1.23); C811(1.23); C718(1.27)  LDD0654  [10]
 LDCM0338  AC73 HCT 116 C448(1.02); C801(1.33); C811(1.33); C718(1.73)  LDD0655  [10]
 LDCM0339  AC74 HCT 116 C448(1.09); C801(1.16); C811(1.16); C718(1.53)  LDD0656  [10]
 LDCM0340  AC75 HCT 116 C448(0.92); C801(1.55); C811(1.55); C718(1.93)  LDD0657  [10]
 LDCM0341  AC76 HCT 116 C448(0.97); C801(1.01); C811(1.01); C718(1.36)  LDD0658  [10]
 LDCM0342  AC77 HCT 116 C448(0.90); C801(1.13); C811(1.13); C718(1.30)  LDD0659  [10]
 LDCM0343  AC78 HCT 116 C448(1.01); C801(1.07); C811(1.07); C718(1.22)  LDD0660  [10]
 LDCM0344  AC79 HCT 116 C448(0.94); C801(1.04); C811(1.04); C718(1.20)  LDD0661  [10]
 LDCM0345  AC8 HCT 116 C448(0.82); C129(1.00); C718(1.06); C801(1.19)  LDD0662  [10]
 LDCM0346  AC80 HCT 116 C448(0.97); C801(1.12); C811(1.12); C718(1.27)  LDD0663  [10]
 LDCM0347  AC81 HCT 116 C801(0.98); C811(0.98); C448(1.01); C718(1.20)  LDD0664  [10]
 LDCM0348  AC82 HCT 116 C448(0.93); C801(1.53); C811(1.53); C718(1.84)  LDD0665  [10]
 LDCM0349  AC83 HCT 116 C801(0.54); C811(0.54); C448(0.79); C718(1.10)  LDD0666  [10]
 LDCM0350  AC84 HCT 116 C801(0.58); C811(0.58); C448(0.85); C718(1.14)  LDD0667  [10]
 LDCM0351  AC85 HCT 116 C801(0.58); C811(0.58); C448(0.80); C129(1.21)  LDD0668  [10]
 LDCM0352  AC86 HCT 116 C801(0.68); C811(0.68); C448(0.84); C718(1.04)  LDD0669  [10]
 LDCM0353  AC87 HCT 116 C801(0.70); C811(0.70); C129(0.96); C448(0.97)  LDD0670  [10]
 LDCM0354  AC88 HCT 116 C801(0.86); C811(0.86); C448(0.94); C718(0.98)  LDD0671  [10]
 LDCM0355  AC89 HCT 116 C448(0.73); C801(0.78); C811(0.78); C718(0.91)  LDD0672  [10]
 LDCM0357  AC90 HCT 116 C801(0.79); C811(0.79); C718(0.98); C448(1.07)  LDD0674  [10]
 LDCM0358  AC91 HCT 116 C801(0.66); C811(0.66); C448(0.72); C718(0.88)  LDD0675  [10]
 LDCM0359  AC92 HCT 116 C801(0.53); C811(0.53); C448(0.70); C718(0.72)  LDD0676  [10]
 LDCM0360  AC93 HCT 116 C448(0.76); C801(0.77); C811(0.77); C718(0.77)  LDD0677  [10]
 LDCM0361  AC94 HCT 116 C801(0.40); C811(0.40); C718(0.79); C448(0.81)  LDD0678  [10]
 LDCM0362  AC95 HCT 116 C718(0.80); C801(0.86); C811(0.86); C448(1.04)  LDD0679  [10]
 LDCM0363  AC96 HCT 116 C801(0.50); C811(0.50); C448(0.71); C718(0.73)  LDD0680  [10]
 LDCM0364  AC97 HCT 116 C448(0.74); C718(0.82); C801(0.93); C811(0.93)  LDD0681  [10]
 LDCM0365  AC98 HCT 116 C448(0.98); C801(1.28); C811(1.28); C718(1.85)  LDD0682  [10]
 LDCM0366  AC99 HCT 116 C448(0.87); C801(0.94); C811(0.94); C718(1.05)  LDD0683  [10]
 LDCM0248  AKOS034007472 HCT 116 C129(0.81); C448(1.00); C718(1.04); C801(1.05)  LDD0565  [10]
 LDCM0356  AKOS034007680 HCT 116 C801(0.83); C811(0.83); C448(1.00); C718(1.11)  LDD0673  [10]
 LDCM0275  AKOS034007705 HCT 116 C448(0.67); C801(1.41); C811(1.41); C718(1.51)  LDD0592  [10]
 LDCM0156  Aniline NCI-H1299 N.A.  LDD0404  [1]
 LDCM0020  ARS-1620 HCC44 C801(1.15); C811(1.15); C381(1.03); C129(0.98)  LDD0078  [10]
 LDCM0088  C45 HEK-293T 15.56  LDD0202  [4]
 LDCM0632  CL-Sc Hep-G2 C592(3.08); C129(2.80)  LDD2227  [14]
 LDCM0367  CL1 HCT 116 C801(0.83); C811(0.83); C718(0.95); C448(1.09)  LDD0684  [10]
 LDCM0368  CL10 HCT 116 C801(1.01); C811(1.01); C448(1.11); C718(1.18)  LDD0685  [10]
 LDCM0369  CL100 HCT 116 C801(0.97); C811(0.97); C129(1.00); C718(1.15)  LDD0686  [10]
 LDCM0370  CL101 HCT 116 C448(0.71); C129(0.94); C718(1.04); C801(1.25)  LDD0687  [10]
 LDCM0371  CL102 HCT 116 C448(0.84); C129(0.93); C718(0.96); C801(1.01)  LDD0688  [10]
 LDCM0372  CL103 HCT 116 C448(0.91); C718(0.97); C801(0.97); C811(0.97)  LDD0689  [10]
 LDCM0373  CL104 HCT 116 C448(0.88); C801(1.01); C811(1.01); C129(1.03)  LDD0690  [10]
 LDCM0374  CL105 HCT 116 C129(0.91); C448(0.92); C718(1.09); C801(1.10)  LDD0691  [10]
 LDCM0375  CL106 HCT 116 C448(0.89); C129(1.29); C801(1.42); C811(1.42)  LDD0692  [10]
 LDCM0376  CL107 HCT 116 C448(0.87); C129(0.90); C801(1.08); C811(1.08)  LDD0693  [10]
 LDCM0377  CL108 HCT 116 C448(0.92); C129(1.07); C801(1.24); C811(1.24)  LDD0694  [10]
 LDCM0378  CL109 HCT 116 C448(0.90); C718(1.24); C801(1.33); C811(1.33)  LDD0695  [10]
 LDCM0379  CL11 HCT 116 C448(0.89); C801(0.91); C811(0.91); C718(1.32)  LDD0696  [10]
 LDCM0380  CL110 HCT 116 C448(0.83); C718(1.27); C129(1.37); C801(1.63)  LDD0697  [10]
 LDCM0381  CL111 HCT 116 C448(1.01); C718(1.11); C129(1.12); C801(1.49)  LDD0698  [10]
 LDCM0382  CL112 HCT 116 C718(0.91); C448(1.02); C801(1.14); C811(1.14)  LDD0699  [10]
 LDCM0383  CL113 HCT 116 C448(1.09); C801(1.32); C811(1.32); C718(1.49)  LDD0700  [10]
 LDCM0384  CL114 HCT 116 C448(1.01); C718(1.20); C801(1.89); C811(1.89)  LDD0701  [10]
 LDCM0385  CL115 HCT 116 C448(0.98); C801(1.28); C811(1.28); C718(1.43)  LDD0702  [10]
 LDCM0386  CL116 HCT 116 C801(0.97); C811(0.97); C448(1.12); C718(1.34)  LDD0703  [10]
 LDCM0387  CL117 HCT 116 C448(0.83); C718(1.45); C801(1.91); C811(1.91)  LDD0704  [10]
 LDCM0388  CL118 HCT 116 C801(0.55); C811(0.55); C448(0.98); C129(1.05)  LDD0705  [10]
 LDCM0389  CL119 HCT 116 C801(0.67); C811(0.67); C448(0.96); C129(1.37)  LDD0706  [10]
 LDCM0390  CL12 HCT 116 C801(1.06); C811(1.06); C448(1.24); C718(1.39)  LDD0707  [10]
 LDCM0391  CL120 HCT 116 C801(0.51); C811(0.51); C448(0.90); C718(2.00)  LDD0708  [10]
 LDCM0392  CL121 HCT 116 C448(1.08); C718(1.10); C801(1.78); C811(1.78)  LDD0709  [10]
 LDCM0393  CL122 HCT 116 C801(1.04); C811(1.04); C718(1.05); C448(1.07)  LDD0710  [10]
 LDCM0394  CL123 HCT 116 C718(0.92); C448(1.03); C801(1.96); C811(1.96)  LDD0711  [10]
 LDCM0395  CL124 HCT 116 C718(0.87); C448(0.93); C801(1.31); C811(1.31)  LDD0712  [10]
 LDCM0396  CL125 HCT 116 C129(0.60); C801(0.93); C811(0.93); C448(0.94)  LDD0713  [10]
 LDCM0397  CL126 HCT 116 C129(0.84); C448(0.93); C801(0.94); C811(0.94)  LDD0714  [10]
 LDCM0398  CL127 HCT 116 C129(0.71); C448(0.86); C718(1.10); C801(1.10)  LDD0715  [10]
 LDCM0399  CL128 HCT 116 C129(0.72); C448(0.87); C801(0.88); C811(0.88)  LDD0716  [10]
 LDCM0400  CL13 HCT 116 C801(0.76); C811(0.76); C718(1.15); C448(1.25)  LDD0717  [10]
 LDCM0401  CL14 HCT 116 C801(0.76); C811(0.76); C718(1.03); C448(1.12)  LDD0718  [10]
 LDCM0402  CL15 HCT 116 C448(0.88); C801(0.93); C811(0.93); C718(0.97)  LDD0719  [10]
 LDCM0403  CL16 HCT 116 C448(0.83); C718(1.05); C801(1.06); C811(1.06)  LDD0720  [10]
 LDCM0404  CL17 HCT 116 C448(0.69); C801(0.90); C811(0.90); C718(0.96)  LDD0721  [10]
 LDCM0405  CL18 HCT 116 C448(0.99); C801(1.02); C811(1.02); C129(1.04)  LDD0722  [10]
 LDCM0406  CL19 HCT 116 C448(0.86); C129(1.04); C718(1.19); C801(1.20)  LDD0723  [10]
 LDCM0407  CL2 HCT 116 C801(0.87); C811(0.87); C448(0.92); C718(0.92)  LDD0724  [10]
 LDCM0408  CL20 HCT 116 C448(0.75); C129(1.06); C801(1.28); C811(1.28)  LDD0725  [10]
 LDCM0409  CL21 HCT 116 C448(0.68); C801(1.34); C811(1.34); C718(1.43)  LDD0726  [10]
 LDCM0410  CL22 HCT 116 C448(0.84); C129(0.92); C801(1.23); C811(1.23)  LDD0727  [10]
 LDCM0411  CL23 HCT 116 C448(0.77); C801(1.02); C811(1.02); C129(1.08)  LDD0728  [10]
 LDCM0412  CL24 HCT 116 C448(0.82); C129(0.91); C801(1.11); C811(1.11)  LDD0729  [10]
 LDCM0413  CL25 HCT 116 C129(1.00); C448(0.78); C718(1.32); C801(1.03)  LDD0730  [10]
 LDCM0414  CL26 HCT 116 C129(1.17); C448(0.80); C718(1.33); C801(1.04)  LDD0731  [10]
 LDCM0415  CL27 HCT 116 C129(0.97); C448(0.91); C718(1.28); C801(0.95)  LDD0732  [10]
 LDCM0416  CL28 HCT 116 C129(1.59); C448(0.74); C718(1.24); C801(1.06)  LDD0733  [10]
 LDCM0417  CL29 HCT 116 C129(1.01); C448(0.71); C718(1.41); C801(1.27)  LDD0734  [10]
 LDCM0418  CL3 HCT 116 C129(1.12); C448(1.00); C718(0.91); C801(1.05)  LDD0735  [10]
 LDCM0419  CL30 HCT 116 C129(0.98); C448(1.03); C718(1.22); C801(1.03)  LDD0736  [10]
 LDCM0420  CL31 HCT 116 C129(1.24); C448(0.93); C718(0.86); C801(1.01)  LDD0737  [10]
 LDCM0421  CL32 HCT 116 C129(1.57); C448(1.08); C718(0.86); C801(1.02)  LDD0738  [10]
 LDCM0422  CL33 HCT 116 C129(4.68); C448(0.90); C718(0.99); C801(0.98)  LDD0739  [10]
 LDCM0423  CL34 HCT 116 C129(3.50); C448(0.88); C718(1.02); C801(1.20)  LDD0740  [10]
 LDCM0424  CL35 HCT 116 C129(1.52); C448(0.88); C718(1.01); C801(1.77)  LDD0741  [10]
 LDCM0425  CL36 HCT 116 C129(1.45); C448(0.87); C718(0.79); C801(1.18)  LDD0742  [10]
 LDCM0426  CL37 HCT 116 C129(1.60); C448(0.88); C718(1.00); C801(1.62)  LDD0743  [10]
 LDCM0428  CL39 HCT 116 C129(1.47); C448(0.80); C718(1.11); C801(1.01)  LDD0745  [10]
 LDCM0429  CL4 HCT 116 C129(1.59); C448(0.91); C718(0.95); C801(0.97)  LDD0746  [10]
 LDCM0430  CL40 HCT 116 C129(1.44); C448(0.82); C718(0.89); C801(1.40)  LDD0747  [10]
 LDCM0431  CL41 HCT 116 C129(1.49); C448(0.90); C718(0.91); C801(1.27)  LDD0748  [10]
 LDCM0432  CL42 HCT 116 C129(2.37); C448(0.94); C718(0.75); C801(1.74)  LDD0749  [10]
 LDCM0433  CL43 HCT 116 C129(2.03); C448(0.97); C718(1.01); C801(1.25)  LDD0750  [10]
 LDCM0434  CL44 HCT 116 C129(2.20); C448(1.02); C718(0.90); C801(1.26)  LDD0751  [10]
 LDCM0435  CL45 HCT 116 C129(2.58); C448(0.97); C718(0.83); C801(1.32)  LDD0752  [10]
 LDCM0436  CL46 HCT 116 C129(1.78); C448(1.00); C718(0.79); C801(0.68)  LDD0753  [10]
 LDCM0437  CL47 HCT 116 C129(0.75); C448(0.88); C718(0.96); C801(0.73)  LDD0754  [10]
 LDCM0438  CL48 HCT 116 C129(0.89); C448(0.95); C718(1.02); C801(0.82)  LDD0755  [10]
 LDCM0439  CL49 HCT 116 C129(0.95); C448(0.91); C718(0.88); C801(0.99)  LDD0756  [10]
 LDCM0440  CL5 HCT 116 C129(1.01); C448(0.96); C718(1.05); C801(1.10)  LDD0757  [10]
 LDCM0441  CL50 HCT 116 C129(0.92); C448(0.90); C718(0.91); C801(0.85)  LDD0758  [10]
 LDCM0442  CL51 HCT 116 C129(0.93); C448(0.94); C718(1.06); C801(0.91)  LDD0759  [10]
 LDCM0443  CL52 HCT 116 C129(1.16); C448(1.00); C718(0.90); C801(1.28)  LDD0760  [10]
 LDCM0444  CL53 HCT 116 C129(0.97); C448(0.76); C718(0.94); C801(1.15)  LDD0761  [10]
 LDCM0445  CL54 HCT 116 C129(0.89); C448(0.89); C718(0.76); C801(0.97)  LDD0762  [10]
 LDCM0446  CL55 HCT 116 C129(1.35); C448(0.89); C718(0.82); C801(0.99)  LDD0763  [10]
 LDCM0447  CL56 HCT 116 C129(0.91); C448(0.88); C718(0.81); C801(0.97)  LDD0764  [10]
 LDCM0448  CL57 HCT 116 C129(0.85); C448(0.89); C718(0.76); C801(0.66)  LDD0765  [10]
 LDCM0449  CL58 HCT 116 C129(1.01); C448(0.91); C718(0.86); C801(0.81)  LDD0766  [10]
 LDCM0450  CL59 HCT 116 C129(0.86); C448(0.90); C718(0.92); C801(1.03)  LDD0767  [10]
 LDCM0451  CL6 HCT 116 C129(1.78); C448(1.00); C718(0.94); C801(1.10)  LDD0768  [10]
 LDCM0452  CL60 HCT 116 C129(0.91); C448(1.06); C718(0.93); C801(0.94)  LDD0769  [10]
 LDCM0453  CL61 HCT 116 C448(1.08); C718(0.98); C801(0.90); C811(0.90)  LDD0770  [10]
 LDCM0454  CL62 HCT 116 C448(1.04); C718(0.93); C801(0.71); C811(0.71)  LDD0771  [10]
 LDCM0455  CL63 HCT 116 C448(0.83); C718(1.23); C801(0.76); C811(0.76)  LDD0772  [10]
 LDCM0456  CL64 HCT 116 C448(1.00); C718(1.32); C801(0.83); C811(0.83)  LDD0773  [10]
 LDCM0457  CL65 HCT 116 C448(1.05); C718(0.98); C801(0.80); C811(0.80)  LDD0774  [10]
 LDCM0458  CL66 HCT 116 C448(0.94); C718(1.34); C801(0.62); C811(0.62)  LDD0775  [10]
 LDCM0459  CL67 HCT 116 C448(1.07); C718(1.27); C801(1.00); C811(1.00)  LDD0776  [10]
 LDCM0460  CL68 HCT 116 C448(0.95); C718(1.25); C801(1.19); C811(1.19)  LDD0777  [10]
 LDCM0461  CL69 HCT 116 C448(1.05); C718(1.02); C801(0.73); C811(0.73)  LDD0778  [10]
 LDCM0462  CL7 HCT 116 C129(1.44); C448(1.39); C718(1.34); C801(0.92)  LDD0779  [10]
 LDCM0463  CL70 HCT 116 C448(0.97); C718(0.99); C801(0.94); C811(0.94)  LDD0780  [10]
 LDCM0464  CL71 HCT 116 C448(0.96); C718(1.21); C801(1.13); C811(1.13)  LDD0781  [10]
 LDCM0465  CL72 HCT 116 C448(0.93); C718(1.10); C801(1.51); C811(1.51)  LDD0782  [10]
 LDCM0466  CL73 HCT 116 C448(0.98); C718(0.92); C801(1.01); C811(1.01)  LDD0783  [10]
 LDCM0467  CL74 HCT 116 C448(1.03); C718(1.29); C801(1.21); C811(1.21)  LDD0784  [10]
 LDCM0469  CL76 HCT 116 C129(0.98); C448(0.69); C718(0.79); C801(1.14)  LDD0786  [10]
 LDCM0470  CL77 HCT 116 C129(1.03); C448(0.60); C718(0.55); C801(1.16)  LDD0787  [10]
 LDCM0471  CL78 HCT 116 C129(1.07); C448(0.64); C718(0.62); C801(1.08)  LDD0788  [10]
 LDCM0472  CL79 HCT 116 C129(1.21); C448(0.80); C718(0.71); C801(0.93)  LDD0789  [10]
 LDCM0473  CL8 HCT 116 C129(7.44); C448(0.72); C718(1.27); C801(1.65)  LDD0790  [10]
 LDCM0474  CL80 HCT 116 C129(0.90); C448(0.72); C718(0.70); C801(0.95)  LDD0791  [10]
 LDCM0475  CL81 HCT 116 C129(1.17); C448(0.74); C718(0.51); C801(0.89)  LDD0792  [10]
 LDCM0476  CL82 HCT 116 C129(1.28); C448(0.72); C718(0.58); C801(0.84)  LDD0793  [10]
 LDCM0477  CL83 HCT 116 C129(1.10); C448(0.66); C718(0.66); C801(0.86)  LDD0794  [10]
 LDCM0478  CL84 HCT 116 C129(1.37); C448(0.82); C718(0.85); C801(0.82)  LDD0795  [10]
 LDCM0479  CL85 HCT 116 C129(1.06); C448(0.66); C718(0.58); C801(1.10)  LDD0796  [10]
 LDCM0480  CL86 HCT 116 C129(0.87); C448(0.71); C718(0.81); C801(0.99)  LDD0797  [10]
 LDCM0481  CL87 HCT 116 C129(0.96); C448(0.76); C718(0.61); C801(0.97)  LDD0798  [10]
 LDCM0482  CL88 HCT 116 C129(1.05); C448(0.68); C718(0.84); C801(0.97)  LDD0799  [10]
 LDCM0483  CL89 HCT 116 C129(1.47); C448(0.74); C718(0.64); C801(0.93)  LDD0800  [10]
 LDCM0484  CL9 HCT 116 C129(1.76); C448(1.19); C718(1.20); C801(0.88)  LDD0801  [10]
 LDCM0485  CL90 HCT 116 C129(1.30); C448(0.58); C718(0.90); C801(1.01)  LDD0802  [10]
 LDCM0486  CL91 HCT 116 C129(1.15); C448(0.93); C718(1.10); C801(1.05)  LDD0803  [10]
 LDCM0487  CL92 HCT 116 C129(2.44); C448(0.93); C718(1.17); C801(0.87)  LDD0804  [10]
 LDCM0488  CL93 HCT 116 C129(2.38); C448(1.11); C718(1.17); C801(0.82)  LDD0805  [10]
 LDCM0489  CL94 HCT 116 C129(1.47); C448(1.27); C718(1.22); C801(1.06)  LDD0806  [10]
 LDCM0490  CL95 HCT 116 C129(1.36); C448(0.89); C718(1.18); C801(1.09)  LDD0807  [10]
 LDCM0491  CL96 HCT 116 C129(1.07); C448(1.26); C718(1.34); C801(1.20)  LDD0808  [10]
 LDCM0492  CL97 HCT 116 C129(0.94); C448(1.14); C718(1.10); C801(1.25)  LDD0809  [10]
 LDCM0493  CL98 HCT 116 C129(1.24); C448(1.04); C718(1.19); C801(1.20)  LDD0810  [10]
 LDCM0494  CL99 HCT 116 C129(0.91); C448(0.97); C718(1.26); C801(1.16)  LDD0811  [10]
 LDCM0634  CY-0357 Hep-G2 C592(0.68)  LDD2228  [14]
 LDCM0028  Dobutamine HEK-293T 4.64  LDD0180  [7]
 LDCM0027  Dopamine HEK-293T 4.31  LDD0179  [7]
 LDCM0495  E2913 HEK-293T C718(0.88); C448(0.93); C592(1.18); C129(1.11)  LDD1698  [22]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C129(12.86); C448(2.69); C381(2.68); C492(0.87)  LDD1702  [5]
 LDCM0625  F8 Ramos C262(1.60); C129(1.14)  LDD2187  [23]
 LDCM0572  Fragment10 MDA-MB-231 C129(10.45)  LDD1389  [24]
 LDCM0573  Fragment11 MDA-MB-231 C129(20.00)  LDD1391  [24]
 LDCM0574  Fragment12 Ramos C129(4.27)  LDD1394  [24]
 LDCM0575  Fragment13 Ramos C129(1.14)  LDD1396  [24]
 LDCM0576  Fragment14 MDA-MB-231 C129(20.00)  LDD1397  [24]
 LDCM0577  Fragment15 Ramos C129(1.69)  LDD1400  [24]
 LDCM0579  Fragment20 MDA-MB-231 C129(2.47)  LDD1402  [24]
 LDCM0580  Fragment21 Ramos C129(1.09)  LDD2195  [23]
 LDCM0581  Fragment22 Ramos C129(1.00)  LDD1407  [24]
 LDCM0582  Fragment23 MDA-MB-231 C129(0.79)  LDD1408  [24]
 LDCM0583  Fragment24 Ramos C129(20.00)  LDD1410  [24]
 LDCM0584  Fragment25 MDA-MB-231 C129(1.10)  LDD1411  [24]
 LDCM0585  Fragment26 Ramos C129(0.94)  LDD1412  [24]
 LDCM0578  Fragment27 MDA-MB-231 C129(1.12)  LDD1401  [24]
 LDCM0586  Fragment28 MDA-MB-231 C129(1.07)  LDD1415  [24]
 LDCM0587  Fragment29 MDA-MB-231 C129(0.71)  LDD1417  [24]
 LDCM0588  Fragment30 MDA-MB-231 C129(1.11)  LDD1419  [24]
 LDCM0589  Fragment31 Ramos C129(1.57)  LDD1422  [24]
 LDCM0590  Fragment32 MDA-MB-231 C129(15.81)  LDD1423  [24]
 LDCM0468  Fragment33 HCT 116 C448(1.06); C718(1.09); C801(0.77); C811(0.77)  LDD0785  [10]
 LDCM0596  Fragment38 Ramos C129(1.75)  LDD1434  [24]
 LDCM0566  Fragment4 Ramos C129(3.36)  LDD1379  [24]
 LDCM0598  Fragment40 MDA-MB-231 C129(1.03)  LDD1436  [24]
 LDCM0599  Fragment41 MDA-MB-231 C129(1.31)  LDD1438  [24]
 LDCM0600  Fragment42 Ramos C129(0.97)  LDD1440  [24]
 LDCM0601  Fragment43 MDA-MB-231 C129(20.00)  LDD1441  [24]
 LDCM0602  Fragment44 MDA-MB-231 C129(0.77)  LDD1443  [24]
 LDCM0605  Fragment47 MDA-MB-231 C129(1.04)  LDD1446  [24]
 LDCM0608  Fragment50 MDA-MB-231 C129(20.00)  LDD1449  [24]
 LDCM0427  Fragment51 HCT 116 C129(2.11); C448(0.81); C718(1.00); C801(1.68)  LDD0744  [10]
 LDCM0610  Fragment52 MDA-MB-231 C129(0.98)  LDD1452  [24]
 LDCM0611  Fragment53 MDA-MB-231 C129(0.98)  LDD1454  [24]
 LDCM0614  Fragment56 MDA-MB-231 C129(0.85)  LDD1458  [24]
 LDCM0569  Fragment7 MDA-MB-231 C129(2.99)  LDD1383  [24]
 LDCM0570  Fragment8 MDA-MB-231 C129(4.68)  LDD1385  [24]
 LDCM0571  Fragment9 MDA-MB-231 C129(2.15)  LDD1387  [24]
 LDCM0116  HHS-0101 DM93 Y341(0.75)  LDD0264  [9]
 LDCM0117  HHS-0201 DM93 Y341(0.63)  LDD0265  [9]
 LDCM0120  HHS-0701 DM93 Y341(4.07)  LDD0268  [9]
 LDCM0022  KB02 HCT 116 C801(13.73); C811(13.73); C718(1.29)  LDD0080  [10]
 LDCM0023  KB03 HCT 116 C801(11.85); C811(11.85); C718(1.10)  LDD0081  [10]
 LDCM0024  KB05 HCT 116 C801(6.22); C811(6.22); C718(1.34)  LDD0082  [10]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C364(1.40); C592(1.12)  LDD2090  [5]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C592(0.90); C129(0.87)  LDD2092  [5]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C364(1.67); C592(1.16)  LDD2094  [5]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C592(1.03)  LDD2098  [5]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C592(1.67); C718(1.14)  LDD2105  [5]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C129(0.98)  LDD2116  [5]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C364(0.31)  LDD2118  [5]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C129(0.64)  LDD2122  [5]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C364(0.44); C592(0.64)  LDD2124  [5]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C592(0.89)  LDD2126  [5]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C592(0.87)  LDD2146  [5]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C364(0.43)  LDD2153  [5]
 LDCM0627  NUDT7-COV-1 HEK-293T C129(0.82)  LDD2206  [25]
 LDCM0628  OTUB2-COV-1 HEK-293T C129(0.34)  LDD2207  [25]
 LDCM0029  Quercetin HEK-293T 8.56  LDD0181  [7]
 LDCM0131  RA190 MM1.R C129(1.28)  LDD0304  [26]
 LDCM0003  Sulforaphane MDA-MB-231 2.08  LDD0160  [6]
 LDCM0021  THZ1 HCT 116 C718(1.20); C129(0.97); C801(1.04); C811(1.04)  LDD2173  [10]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Microtubule-associated tumor suppressor candidate 2 (MTUS2) MTUS1 family Q5JR59

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
3 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
4 Discovery of Potent and Selective Inhibitors against Protein-Derived Electrophilic Cofactors. J Am Chem Soc. 2022 Mar 30;144(12):5377-5388. doi: 10.1021/jacs.1c12748. Epub 2022 Mar 2.
5 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
6 Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane. Chem Commun (Camb). 2017 May 4;53(37):5182-5185. doi: 10.1039/c6cc08797c.
Mass spectrometry data entry: PXD006279
7 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
8 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
9 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
10 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
11 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
12 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
13 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
14 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
15 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
16 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
17 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
18 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
19 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
20 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
21 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
22 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
23 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
24 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
25 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.
26 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.