Details of the Target

General Information of Target

Target ID LDTP01532
Target Name ZW10 interactor (ZWINT)
Gene Name ZWINT
Gene ID 11130
Synonyms
ZW10 interactor; ZW10-interacting protein 1; Zwint-1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVA
DFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQ
MEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTG
TQQELDRVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKP
QQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
Target Type
Literature-reported
Target Bioclass
Other
Subcellular location
Nucleus
Function Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
TTD ID
T95621
Uniprot ID
O95229
DrugMap ID
TTWY768
Ensemble ID
ENST00000361148.6
HGNC ID
HGNC:13195

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AN3CA SNV: p.D50G; p.R208M .
JHH7 SNV: p.E5V Alk-rapa    Probe Info 
MEWO SNV: p.P78S .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 14 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K111(10.00)  LDD0277  [1]
m-APA
 Probe Info  		15.00  LDD0403  [2]
Curcusone 37
 Probe Info  		2.16  LDD0188  [3]
AHL-Pu-1
 Probe Info  		C54(4.70)  LDD0169  [4]
DBIA
 Probe Info  		C54(11.79)  LDD0209  [5]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [6]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [6]
IPIAA_L
 Probe Info  		N.A.  LDD0031  [7]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [6]
NAIA_4
 Probe Info  		N.A.  LDD2226  [8]
Compound 11
 Probe Info  		N.A.  LDD2213  [9]
IPM
 Probe Info  		N.A.  LDD2156  [10]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [11]
AOyne
 Probe Info  		14.20  LDD0443  [12]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Alk-rapa
 Probe Info  		3.30  LDD0213  [13]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C54(4.70)  LDD0169  [4]
 LDCM0214  AC1 PaTu 8988t C54(0.64)  LDD1093  [14]
 LDCM0230  AC113 PaTu 8988t C54(1.07)  LDD1109  [14]
 LDCM0231  AC114 PaTu 8988t C54(0.79)  LDD1110  [14]
 LDCM0232  AC115 PaTu 8988t C54(1.06)  LDD1111  [14]
 LDCM0233  AC116 PaTu 8988t C54(0.92)  LDD1112  [14]
 LDCM0234  AC117 PaTu 8988t C54(1.29)  LDD1113  [14]
 LDCM0235  AC118 PaTu 8988t C54(0.83)  LDD1114  [14]
 LDCM0236  AC119 PaTu 8988t C54(0.92)  LDD1115  [14]
 LDCM0238  AC120 PaTu 8988t C54(0.86)  LDD1117  [14]
 LDCM0239  AC121 PaTu 8988t C54(0.82)  LDD1118  [14]
 LDCM0240  AC122 PaTu 8988t C54(1.06)  LDD1119  [14]
 LDCM0241  AC123 PaTu 8988t C54(1.05)  LDD1120  [14]
 LDCM0242  AC124 PaTu 8988t C54(1.12)  LDD1121  [14]
 LDCM0243  AC125 PaTu 8988t C54(0.91)  LDD1122  [14]
 LDCM0244  AC126 PaTu 8988t C54(0.69)  LDD1123  [14]
 LDCM0245  AC127 PaTu 8988t C54(0.68)  LDD1124  [14]
 LDCM0259  AC14 HEK-293T C54(1.03)  LDD1512  [15]
 LDCM0279  AC2 PaTu 8988t C54(1.12)  LDD1158  [14]
 LDCM0281  AC21 HEK-293T C54(1.07)  LDD1520  [15]
 LDCM0282  AC22 HEK-293T C54(1.13)  LDD1521  [15]
 LDCM0285  AC25 PaTu 8988t C54(0.90)  LDD1164  [14]
 LDCM0286  AC26 PaTu 8988t C54(0.96)  LDD1165  [14]
 LDCM0287  AC27 PaTu 8988t C54(1.33)  LDD1166  [14]
 LDCM0288  AC28 PaTu 8988t C54(1.42)  LDD1167  [14]
 LDCM0289  AC29 PaTu 8988t C54(0.95)  LDD1168  [14]
 LDCM0290  AC3 PaTu 8988t C54(1.07)  LDD1169  [14]
 LDCM0291  AC30 PaTu 8988t C54(1.05)  LDD1170  [14]
 LDCM0292  AC31 PaTu 8988t C54(1.04)  LDD1171  [14]
 LDCM0293  AC32 PaTu 8988t C54(0.92)  LDD1172  [14]
 LDCM0294  AC33 PaTu 8988t C54(1.27)  LDD1173  [14]
 LDCM0295  AC34 PaTu 8988t C54(1.34)  LDD1174  [14]
 LDCM0296  AC35 PaTu 8988t C54(1.10)  LDD1175  [14]
 LDCM0297  AC36 PaTu 8988t C54(1.17)  LDD1176  [14]
 LDCM0298  AC37 PaTu 8988t C54(1.57)  LDD1177  [14]
 LDCM0299  AC38 PaTu 8988t C54(1.21)  LDD1178  [14]
 LDCM0300  AC39 PaTu 8988t C54(1.41)  LDD1179  [14]
 LDCM0301  AC4 PaTu 8988t C54(1.05)  LDD1180  [14]
 LDCM0302  AC40 PaTu 8988t C54(1.26)  LDD1181  [14]
 LDCM0303  AC41 PaTu 8988t C54(0.96)  LDD1182  [14]
 LDCM0304  AC42 PaTu 8988t C54(0.99)  LDD1183  [14]
 LDCM0305  AC43 PaTu 8988t C54(1.09)  LDD1184  [14]
 LDCM0306  AC44 PaTu 8988t C54(1.12)  LDD1185  [14]
 LDCM0307  AC45 PaTu 8988t C54(1.14)  LDD1186  [14]
 LDCM0308  AC46 PaTu 8988t C54(1.05)  LDD1187  [14]
 LDCM0309  AC47 PaTu 8988t C54(1.15)  LDD1188  [14]
 LDCM0310  AC48 PaTu 8988t C54(1.55)  LDD1189  [14]
 LDCM0311  AC49 PaTu 8988t C54(1.52)  LDD1190  [14]
 LDCM0312  AC5 PaTu 8988t C54(1.32)  LDD1191  [14]
 LDCM0313  AC50 PaTu 8988t C54(1.65)  LDD1192  [14]
 LDCM0314  AC51 PaTu 8988t C54(0.97)  LDD1193  [14]
 LDCM0315  AC52 PaTu 8988t C54(1.44)  LDD1194  [14]
 LDCM0316  AC53 PaTu 8988t C54(2.09)  LDD1195  [14]
 LDCM0317  AC54 PaTu 8988t C54(1.56)  LDD1196  [14]
 LDCM0318  AC55 PaTu 8988t C54(1.56)  LDD1197  [14]
 LDCM0319  AC56 PaTu 8988t C54(1.40)  LDD1198  [14]
 LDCM0323  AC6 HEK-293T C54(1.01)  LDD1562  [15]
 LDCM0325  AC61 HEK-293T C54(1.09)  LDD1564  [15]
 LDCM0326  AC62 HEK-293T C54(1.08)  LDD1565  [15]
 LDCM0248  AKOS034007472 HEK-293T C54(1.08)  LDD1511  [15]
 LDCM0156  Aniline NCI-H1299 15.00  LDD0403  [2]
 LDCM0630  CCW28-3 231MFP C54(1.91)  LDD2214  [16]
 LDCM0368  CL10 HEK-293T C54(2.41)  LDD1572  [15]
 LDCM0369  CL100 PaTu 8988t C54(0.88)  LDD1248  [14]
 LDCM0372  CL103 HEK-293T C54(0.99)  LDD1576  [15]
 LDCM0376  CL107 HEK-293T C54(0.89)  LDD1580  [15]
 LDCM0381  CL111 HEK-293T C54(1.08)  LDD1585  [15]
 LDCM0382  CL112 PaTu 8988t C54(1.06)  LDD1261  [14]
 LDCM0383  CL113 PaTu 8988t C54(1.05)  LDD1262  [14]
 LDCM0384  CL114 PaTu 8988t C54(1.01)  LDD1263  [14]
 LDCM0385  CL115 PaTu 8988t C54(1.26)  LDD1264  [14]
 LDCM0386  CL116 PaTu 8988t C54(0.93)  LDD1265  [14]
 LDCM0387  CL117 PaTu 8988t C54(0.93)  LDD1266  [14]
 LDCM0388  CL118 PaTu 8988t C54(0.93)  LDD1267  [14]
 LDCM0389  CL119 PaTu 8988t C54(1.00)  LDD1268  [14]
 LDCM0391  CL120 PaTu 8988t C54(0.89)  LDD1270  [14]
 LDCM0392  CL121 PaTu 8988t C54(1.61)  LDD1271  [14]
 LDCM0393  CL122 PaTu 8988t C54(1.51)  LDD1272  [14]
 LDCM0394  CL123 PaTu 8988t C54(2.58)  LDD1273  [14]
 LDCM0395  CL124 PaTu 8988t C54(1.27)  LDD1274  [14]
 LDCM0398  CL127 HEK-293T C54(1.05)  LDD1602  [15]
 LDCM0402  CL15 HEK-293T C54(1.51)  LDD1606  [15]
 LDCM0409  CL21 HEK-293T C54(1.59)  LDD1613  [15]
 LDCM0410  CL22 HEK-293T C54(0.96)  LDD1614  [15]
 LDCM0415  CL27 HEK-293T C54(0.96)  LDD1619  [15]
 LDCM0418  CL3 HEK-293T C54(1.20)  LDD1622  [15]
 LDCM0422  CL33 HEK-293T C54(1.98)  LDD1626  [15]
 LDCM0423  CL34 HEK-293T C54(1.10)  LDD1627  [15]
 LDCM0428  CL39 HEK-293T C54(1.20)  LDD1632  [15]
 LDCM0435  CL45 HEK-293T C54(1.39)  LDD1639  [15]
 LDCM0436  CL46 HEK-293T C54(1.07)  LDD1640  [15]
 LDCM0448  CL57 HEK-293T C54(1.38)  LDD1651  [15]
 LDCM0449  CL58 HEK-293T C54(1.06)  LDD1652  [15]
 LDCM0453  CL61 PaTu 8988t C54(1.52)  LDD1332  [14]
 LDCM0454  CL62 PaTu 8988t C54(1.86)  LDD1333  [14]
 LDCM0455  CL63 PaTu 8988t C54(1.03)  LDD1334  [14]
 LDCM0456  CL64 PaTu 8988t C54(0.99)  LDD1335  [14]
 LDCM0457  CL65 PaTu 8988t C54(1.07)  LDD1336  [14]
 LDCM0458  CL66 PaTu 8988t C54(0.92)  LDD1337  [14]
 LDCM0459  CL67 PaTu 8988t C54(0.74)  LDD1338  [14]
 LDCM0460  CL68 PaTu 8988t C54(1.07)  LDD1339  [14]
 LDCM0461  CL69 PaTu 8988t C54(1.35)  LDD1340  [14]
 LDCM0463  CL70 PaTu 8988t C54(0.86)  LDD1342  [14]
 LDCM0464  CL71 PaTu 8988t C54(1.03)  LDD1343  [14]
 LDCM0465  CL72 PaTu 8988t C54(0.93)  LDD1344  [14]
 LDCM0466  CL73 PaTu 8988t C54(1.15)  LDD1345  [14]
 LDCM0467  CL74 PaTu 8988t C54(0.95)  LDD1346  [14]
 LDCM0469  CL76 PaTu 8988t C54(1.10)  LDD1348  [14]
 LDCM0470  CL77 PaTu 8988t C54(1.29)  LDD1349  [14]
 LDCM0471  CL78 PaTu 8988t C54(1.28)  LDD1350  [14]
 LDCM0472  CL79 PaTu 8988t C54(1.60)  LDD1351  [14]
 LDCM0474  CL80 PaTu 8988t C54(1.28)  LDD1353  [14]
 LDCM0475  CL81 PaTu 8988t C54(1.25)  LDD1354  [14]
 LDCM0476  CL82 PaTu 8988t C54(1.22)  LDD1355  [14]
 LDCM0477  CL83 PaTu 8988t C54(1.41)  LDD1356  [14]
 LDCM0478  CL84 PaTu 8988t C54(1.29)  LDD1357  [14]
 LDCM0479  CL85 PaTu 8988t C54(1.56)  LDD1358  [14]
 LDCM0480  CL86 PaTu 8988t C54(1.32)  LDD1359  [14]
 LDCM0481  CL87 PaTu 8988t C54(1.54)  LDD1360  [14]
 LDCM0482  CL88 PaTu 8988t C54(1.53)  LDD1361  [14]
 LDCM0483  CL89 PaTu 8988t C54(1.45)  LDD1362  [14]
 LDCM0484  CL9 HEK-293T C54(1.22)  LDD1687  [15]
 LDCM0485  CL90 PaTu 8988t C54(1.54)  LDD1364  [14]
 LDCM0486  CL91 PaTu 8988t C54(0.84)  LDD1365  [14]
 LDCM0487  CL92 PaTu 8988t C54(0.65)  LDD1366  [14]
 LDCM0488  CL93 PaTu 8988t C54(0.80)  LDD1367  [14]
 LDCM0489  CL94 PaTu 8988t C54(1.10)  LDD1368  [14]
 LDCM0490  CL95 PaTu 8988t C54(0.91)  LDD1369  [14]
 LDCM0491  CL96 PaTu 8988t C54(0.74)  LDD1370  [14]
 LDCM0492  CL97 PaTu 8988t C54(0.73)  LDD1371  [14]
 LDCM0493  CL98 PaTu 8988t C54(0.94)  LDD1372  [14]
 LDCM0494  CL99 PaTu 8988t C54(0.75)  LDD1373  [14]
 LDCM0033  Curcusone1d MCF-7 2.16  LDD0188  [3]
 LDCM0495  E2913 HEK-293T C54(1.02)  LDD1698  [15]
 LDCM0572  Fragment10 Ramos C54(1.03)  LDD1390  [17]
 LDCM0573  Fragment11 MDA-MB-231 C54(3.26)  LDD1391  [17]
 LDCM0574  Fragment12 MDA-MB-231 C54(20.00)  LDD1393  [17]
 LDCM0575  Fragment13 Ramos C54(0.91)  LDD1396  [17]
 LDCM0576  Fragment14 MDA-MB-231 C54(2.45)  LDD1397  [17]
 LDCM0579  Fragment20 Ramos C54(2.41)  LDD1403  [17]
 LDCM0580  Fragment21 MDA-MB-231 C54(1.78)  LDD1404  [17]
 LDCM0584  Fragment25 MDA-MB-231 C54(1.10)  LDD1411  [17]
 LDCM0585  Fragment26 Ramos C54(0.86)  LDD1412  [17]
 LDCM0578  Fragment27 MDA-MB-231 C54(0.76)  LDD1401  [17]
 LDCM0586  Fragment28 Ramos C54(1.07)  LDD1416  [17]
 LDCM0587  Fragment29 MDA-MB-231 C54(1.05)  LDD1417  [17]
 LDCM0588  Fragment30 MDA-MB-231 C54(1.86)  LDD1419  [17]
 LDCM0590  Fragment32 MDA-MB-231 C54(4.52)  LDD1423  [17]
 LDCM0468  Fragment33 PaTu 8988t C54(1.00)  LDD1347  [14]
 LDCM0592  Fragment34 MDA-MB-231 C54(0.76)  LDD1427  [17]
 LDCM0593  Fragment35 Ramos C54(1.16)  LDD1430  [17]
 LDCM0595  Fragment37 Ramos C54(1.05)  LDD1432  [17]
 LDCM0596  Fragment38 MDA-MB-231 C54(1.11)  LDD1433  [17]
 LDCM0566  Fragment4 MDA-MB-231 C54(3.35)  LDD1378  [17]
 LDCM0599  Fragment41 Ramos C54(1.45)  LDD1439  [17]
 LDCM0600  Fragment42 Ramos C54(1.06)  LDD1440  [17]
 LDCM0601  Fragment43 MDA-MB-231 C54(2.79)  LDD1441  [17]
 LDCM0602  Fragment44 MDA-MB-231 C54(0.96)  LDD1443  [17]
 LDCM0607  Fragment49 MDA-MB-231 C54(4.60)  LDD1448  [17]
 LDCM0427  Fragment51 Ramos C54(0.64)  LDD1451  [17]
 LDCM0610  Fragment52 MDA-MB-231 C54(1.26)  LDD1452  [17]
 LDCM0611  Fragment53 MDA-MB-231 C54(0.98)  LDD1454  [17]
 LDCM0614  Fragment56 MDA-MB-231 C54(1.05)  LDD1458  [17]
 LDCM0569  Fragment7 MDA-MB-231 C54(1.56)  LDD1383  [17]
 LDCM0570  Fragment8 Ramos C54(1.25)  LDD1386  [17]
 LDCM0571  Fragment9 MDA-MB-231 C54(1.91)  LDD1387  [17]
 LDCM0022  KB02 MDA-MB-231 C54(20.00)  LDD1374  [17]
 LDCM0023  KB03 Jurkat C54(11.79)  LDD0209  [5]
 LDCM0024  KB05 NCI-H1155 C54(4.18)  LDD3342  [18]
 LDCM0090  Rapamycin JHH-7 3.30  LDD0213  [13]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tumor susceptibility gene 101 protein (TSG101) Ubiquitin-conjugating enzyme family Q99816
Transporter and channel
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Beclin-1 (BECN1) Beclin family Q14457
Nucleoporin p54 (NUP54) NUP54 family Q7Z3B4
Nucleoporin p58/p45 (NUP58) NUP58 family Q9BVL2
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Krueppel-like factor 11 (KLF11) Sp1 C2H2-type zinc-finger protein family O14901
Mesogenin-1 (MSGN1) . A6NI15
Other
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein FAM90A1 (FAM90A1) FAM90 family Q86YD7
Keratin, type II cytoskeletal 75 (KRT75) Intermediate filament family O95678
Kinetochore protein NDC80 homolog (NDC80) NDC80/HEC1 family O14777
Pre-mRNA-splicing factor SPF27 (BCAS2) SPF27 family O75934
Centromere/kinetochore protein zw10 homolog (ZW10) ZW10 family O43264

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
3 Total Synthesis and Target Identification of the Curcusone Diterpenes. J Am Chem Soc. 2021 Mar 24;143(11):4379-4386. doi: 10.1021/jacs.1c00557. Epub 2021 Mar 11.
4 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
5 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
10 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
11 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
12 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
13 Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth. Cell Chem Biol. 2022 Mar 17;29(3):373-385.e6. doi: 10.1016/j.chembiol.2021.10.006. Epub 2021 Oct 26.
14 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
15 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
16 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
17 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
18 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840