Details of the Target
General Information of Target
Target ID | LDTP11272 | |||||
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Target Name | ER membrane protein complex subunit 6 (EMC6) | |||||
Gene Name | EMC6 | |||||
Gene ID | 83460 | |||||
Synonyms |
TMEM93; ER membrane protein complex subunit 6; Transmembrane protein 93 |
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3D Structure | ||||||
Sequence |
MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVEL
KNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVT GLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQ LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE ELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLL IFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEAS MKPFISSKQILTM |
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Target Bioclass |
Transporter and channel
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Family |
EMC6 family
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Subcellular location |
Endoplasmic reticulum membrane
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Function |
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).
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Uniprot ID | ||||||
Ensemble ID | ||||||
HGNC ID |
Probe(s) Labeling This Target
ABPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
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C-Sul Probe Info |
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3.58 | LDD0066 | [1] | |
BTD Probe Info |
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C29(0.45) | LDD2096 | [2] | |
Acrolein Probe Info |
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N.A. | LDD0222 | [3] | |
DBIA Probe Info |
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C29(0.88) | LDD0531 | [4] | |
4-Iodoacetamidophenylacetylene Probe Info |
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N.A. | LDD0038 | [5] | |
IA-alkyne Probe Info |
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N.A. | LDD0036 | [5] | |
Lodoacetamide azide Probe Info |
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N.A. | LDD0037 | [5] | |
NAIA_5 Probe Info |
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N.A. | LDD2224 | [6] | |
TFBX Probe Info |
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N.A. | LDD0027 | [7] | |
WYneO Probe Info |
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N.A. | LDD0022 | [8] | |
IPM Probe Info |
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N.A. | LDD0005 | [8] | |
Crotonaldehyde Probe Info |
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N.A. | LDD0219 | [3] |
Competitor(s) Related to This Target
Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
---|---|---|---|---|---|
LDCM0524 | 2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide | MDA-MB-231 | C29(1.40) | LDD2117 | [2] |
LDCM0214 | AC1 | HCT 116 | C29(0.88) | LDD0531 | [4] |
LDCM0215 | AC10 | HCT 116 | C29(0.84) | LDD0532 | [4] |
LDCM0216 | AC100 | HCT 116 | C29(0.62) | LDD0533 | [4] |
LDCM0217 | AC101 | HCT 116 | C29(0.55) | LDD0534 | [4] |
LDCM0218 | AC102 | HCT 116 | C29(0.68) | LDD0535 | [4] |
LDCM0219 | AC103 | HCT 116 | C29(0.52) | LDD0536 | [4] |
LDCM0220 | AC104 | HCT 116 | C29(0.65) | LDD0537 | [4] |
LDCM0221 | AC105 | HCT 116 | C29(0.59) | LDD0538 | [4] |
LDCM0222 | AC106 | HCT 116 | C29(0.56) | LDD0539 | [4] |
LDCM0223 | AC107 | HCT 116 | C29(0.56) | LDD0540 | [4] |
LDCM0224 | AC108 | HCT 116 | C29(0.59) | LDD0541 | [4] |
LDCM0225 | AC109 | HCT 116 | C29(0.65) | LDD0542 | [4] |
LDCM0226 | AC11 | HCT 116 | C29(0.89) | LDD0543 | [4] |
LDCM0227 | AC110 | HCT 116 | C29(0.59) | LDD0544 | [4] |
LDCM0228 | AC111 | HCT 116 | C29(0.57) | LDD0545 | [4] |
LDCM0229 | AC112 | HCT 116 | C29(0.54) | LDD0546 | [4] |
LDCM0230 | AC113 | HCT 116 | C29(0.96) | LDD0547 | [4] |
LDCM0231 | AC114 | HCT 116 | C29(0.80) | LDD0548 | [4] |
LDCM0232 | AC115 | HCT 116 | C29(0.83) | LDD0549 | [4] |
LDCM0233 | AC116 | HCT 116 | C29(0.84) | LDD0550 | [4] |
LDCM0234 | AC117 | HCT 116 | C29(0.88) | LDD0551 | [4] |
LDCM0235 | AC118 | HCT 116 | C29(0.89) | LDD0552 | [4] |
LDCM0236 | AC119 | HCT 116 | C29(0.97) | LDD0553 | [4] |
LDCM0237 | AC12 | HCT 116 | C29(0.98) | LDD0554 | [4] |
LDCM0238 | AC120 | HCT 116 | C29(0.96) | LDD0555 | [4] |
LDCM0239 | AC121 | HCT 116 | C29(1.10) | LDD0556 | [4] |
LDCM0240 | AC122 | HCT 116 | C29(0.87) | LDD0557 | [4] |
LDCM0241 | AC123 | HCT 116 | C29(1.05) | LDD0558 | [4] |
LDCM0242 | AC124 | HCT 116 | C29(1.00) | LDD0559 | [4] |
LDCM0243 | AC125 | HCT 116 | C29(0.91) | LDD0560 | [4] |
LDCM0244 | AC126 | HCT 116 | C29(0.90) | LDD0561 | [4] |
LDCM0245 | AC127 | HCT 116 | C29(0.87) | LDD0562 | [4] |
LDCM0246 | AC128 | HCT 116 | C29(1.03) | LDD0563 | [4] |
LDCM0247 | AC129 | HCT 116 | C29(1.05) | LDD0564 | [4] |
LDCM0249 | AC130 | HCT 116 | C29(0.86) | LDD0566 | [4] |
LDCM0250 | AC131 | HCT 116 | C29(0.97) | LDD0567 | [4] |
LDCM0251 | AC132 | HCT 116 | C29(0.96) | LDD0568 | [4] |
LDCM0252 | AC133 | HCT 116 | C29(1.02) | LDD0569 | [4] |
LDCM0253 | AC134 | HCT 116 | C29(0.79) | LDD0570 | [4] |
LDCM0254 | AC135 | HCT 116 | C29(0.87) | LDD0571 | [4] |
LDCM0255 | AC136 | HCT 116 | C29(0.94) | LDD0572 | [4] |
LDCM0256 | AC137 | HCT 116 | C29(0.94) | LDD0573 | [4] |
LDCM0257 | AC138 | HCT 116 | C29(0.87) | LDD0574 | [4] |
LDCM0258 | AC139 | HCT 116 | C29(0.88) | LDD0575 | [4] |
LDCM0259 | AC14 | HCT 116 | C29(0.90) | LDD0576 | [4] |
LDCM0260 | AC140 | HCT 116 | C29(0.87) | LDD0577 | [4] |
LDCM0261 | AC141 | HCT 116 | C29(0.79) | LDD0578 | [4] |
LDCM0262 | AC142 | HCT 116 | C29(1.01) | LDD0579 | [4] |
LDCM0263 | AC143 | HCT 116 | C29(0.75) | LDD0580 | [4] |
LDCM0264 | AC144 | HCT 116 | C29(0.62) | LDD0581 | [4] |
LDCM0265 | AC145 | HCT 116 | C29(0.70) | LDD0582 | [4] |
LDCM0266 | AC146 | HCT 116 | C29(0.65) | LDD0583 | [4] |
LDCM0267 | AC147 | HCT 116 | C29(0.75) | LDD0584 | [4] |
LDCM0268 | AC148 | HCT 116 | C29(0.56) | LDD0585 | [4] |
LDCM0269 | AC149 | HCT 116 | C29(0.60) | LDD0586 | [4] |
LDCM0270 | AC15 | HCT 116 | C29(0.83) | LDD0587 | [4] |
LDCM0271 | AC150 | HCT 116 | C29(0.73) | LDD0588 | [4] |
LDCM0272 | AC151 | HCT 116 | C29(0.74) | LDD0589 | [4] |
LDCM0273 | AC152 | HCT 116 | C29(0.67) | LDD0590 | [4] |
LDCM0274 | AC153 | HCT 116 | C29(0.58) | LDD0591 | [4] |
LDCM0621 | AC154 | HCT 116 | C29(0.61) | LDD2158 | [4] |
LDCM0622 | AC155 | HCT 116 | C29(0.55) | LDD2159 | [4] |
LDCM0623 | AC156 | HCT 116 | C29(0.87) | LDD2160 | [4] |
LDCM0624 | AC157 | HCT 116 | C29(0.70) | LDD2161 | [4] |
LDCM0276 | AC17 | HCT 116 | C29(1.01) | LDD0593 | [4] |
LDCM0277 | AC18 | HCT 116 | C29(0.94) | LDD0594 | [4] |
LDCM0278 | AC19 | HCT 116 | C29(0.86) | LDD0595 | [4] |
LDCM0279 | AC2 | HCT 116 | C29(1.00) | LDD0596 | [4] |
LDCM0280 | AC20 | HCT 116 | C29(0.94) | LDD0597 | [4] |
LDCM0281 | AC21 | HCT 116 | C29(0.95) | LDD0598 | [4] |
LDCM0282 | AC22 | HCT 116 | C29(1.11) | LDD0599 | [4] |
LDCM0283 | AC23 | HCT 116 | C29(1.02) | LDD0600 | [4] |
LDCM0284 | AC24 | HCT 116 | C29(1.02) | LDD0601 | [4] |
LDCM0285 | AC25 | HCT 116 | C29(0.90) | LDD0602 | [4] |
LDCM0286 | AC26 | HCT 116 | C29(0.75) | LDD0603 | [4] |
LDCM0287 | AC27 | HCT 116 | C29(0.73) | LDD0604 | [4] |
LDCM0288 | AC28 | HCT 116 | C29(0.75) | LDD0605 | [4] |
LDCM0289 | AC29 | HCT 116 | C29(0.66) | LDD0606 | [4] |
LDCM0290 | AC3 | HCT 116 | C29(1.05) | LDD0607 | [4] |
LDCM0291 | AC30 | HCT 116 | C29(0.68) | LDD0608 | [4] |
LDCM0292 | AC31 | HCT 116 | C29(0.75) | LDD0609 | [4] |
LDCM0293 | AC32 | HCT 116 | C29(0.65) | LDD0610 | [4] |
LDCM0294 | AC33 | HCT 116 | C29(0.67) | LDD0611 | [4] |
LDCM0295 | AC34 | HCT 116 | C29(0.68) | LDD0612 | [4] |
LDCM0296 | AC35 | HCT 116 | C29(1.14) | LDD0613 | [4] |
LDCM0297 | AC36 | HCT 116 | C29(1.06) | LDD0614 | [4] |
LDCM0298 | AC37 | HCT 116 | C29(1.10) | LDD0615 | [4] |
LDCM0299 | AC38 | HCT 116 | C29(0.98) | LDD0616 | [4] |
LDCM0300 | AC39 | HCT 116 | C29(1.05) | LDD0617 | [4] |
LDCM0301 | AC4 | HCT 116 | C29(0.98) | LDD0618 | [4] |
LDCM0302 | AC40 | HCT 116 | C29(0.96) | LDD0619 | [4] |
LDCM0303 | AC41 | HCT 116 | C29(0.88) | LDD0620 | [4] |
LDCM0304 | AC42 | HCT 116 | C29(0.86) | LDD0621 | [4] |
LDCM0305 | AC43 | HCT 116 | C29(0.79) | LDD0622 | [4] |
LDCM0306 | AC44 | HCT 116 | C29(0.96) | LDD0623 | [4] |
LDCM0307 | AC45 | HCT 116 | C29(1.01) | LDD0624 | [4] |
LDCM0308 | AC46 | HCT 116 | C29(0.79) | LDD0625 | [4] |
LDCM0309 | AC47 | HCT 116 | C29(0.97) | LDD0626 | [4] |
LDCM0310 | AC48 | HCT 116 | C29(0.83) | LDD0627 | [4] |
LDCM0311 | AC49 | HCT 116 | C29(0.90) | LDD0628 | [4] |
LDCM0312 | AC5 | HCT 116 | C29(1.00) | LDD0629 | [4] |
LDCM0313 | AC50 | HCT 116 | C29(0.86) | LDD0630 | [4] |
LDCM0314 | AC51 | HCT 116 | C29(1.01) | LDD0631 | [4] |
LDCM0315 | AC52 | HCT 116 | C29(1.02) | LDD0632 | [4] |
LDCM0316 | AC53 | HCT 116 | C29(0.87) | LDD0633 | [4] |
LDCM0317 | AC54 | HCT 116 | C29(1.09) | LDD0634 | [4] |
LDCM0318 | AC55 | HCT 116 | C29(0.89) | LDD0635 | [4] |
LDCM0319 | AC56 | HCT 116 | C29(0.89) | LDD0636 | [4] |
LDCM0320 | AC57 | HCT 116 | C29(0.92) | LDD0637 | [4] |
LDCM0321 | AC58 | HCT 116 | C29(0.70) | LDD0638 | [4] |
LDCM0322 | AC59 | HCT 116 | C29(0.89) | LDD0639 | [4] |
LDCM0323 | AC6 | HCT 116 | C29(0.78) | LDD0640 | [4] |
LDCM0324 | AC60 | HCT 116 | C29(0.78) | LDD0641 | [4] |
LDCM0325 | AC61 | HCT 116 | C29(0.78) | LDD0642 | [4] |
LDCM0326 | AC62 | HCT 116 | C29(0.75) | LDD0643 | [4] |
LDCM0327 | AC63 | HCT 116 | C29(0.94) | LDD0644 | [4] |
LDCM0328 | AC64 | HCT 116 | C29(0.79) | LDD0645 | [4] |
LDCM0329 | AC65 | HCT 116 | C29(0.80) | LDD0646 | [4] |
LDCM0330 | AC66 | HCT 116 | C29(0.83) | LDD0647 | [4] |
LDCM0331 | AC67 | HCT 116 | C29(0.68) | LDD0648 | [4] |
LDCM0332 | AC68 | HCT 116 | C29(1.05) | LDD0649 | [4] |
LDCM0333 | AC69 | HCT 116 | C29(1.10) | LDD0650 | [4] |
LDCM0334 | AC7 | HCT 116 | C29(1.03) | LDD0651 | [4] |
LDCM0335 | AC70 | HCT 116 | C29(0.99) | LDD0652 | [4] |
LDCM0336 | AC71 | HCT 116 | C29(1.16) | LDD0653 | [4] |
LDCM0337 | AC72 | HCT 116 | C29(1.07) | LDD0654 | [4] |
LDCM0338 | AC73 | HCT 116 | C29(1.06) | LDD0655 | [4] |
LDCM0339 | AC74 | HCT 116 | C29(1.16) | LDD0656 | [4] |
LDCM0340 | AC75 | HCT 116 | C29(1.09) | LDD0657 | [4] |
LDCM0341 | AC76 | HCT 116 | C29(1.19) | LDD0658 | [4] |
LDCM0342 | AC77 | HCT 116 | C29(0.95) | LDD0659 | [4] |
LDCM0343 | AC78 | HCT 116 | C29(0.95) | LDD0660 | [4] |
LDCM0344 | AC79 | HCT 116 | C29(1.04) | LDD0661 | [4] |
LDCM0345 | AC8 | HCT 116 | C29(0.91) | LDD0662 | [4] |
LDCM0346 | AC80 | HCT 116 | C29(1.01) | LDD0663 | [4] |
LDCM0347 | AC81 | HCT 116 | C29(1.34) | LDD0664 | [4] |
LDCM0348 | AC82 | HCT 116 | C29(1.03) | LDD0665 | [4] |
LDCM0349 | AC83 | HCT 116 | C29(0.67) | LDD0666 | [4] |
LDCM0350 | AC84 | HCT 116 | C29(0.70) | LDD0667 | [4] |
LDCM0351 | AC85 | HCT 116 | C29(0.64) | LDD0668 | [4] |
LDCM0352 | AC86 | HCT 116 | C29(0.71) | LDD0669 | [4] |
LDCM0353 | AC87 | HCT 116 | C29(0.86) | LDD0670 | [4] |
LDCM0354 | AC88 | HCT 116 | C29(0.73) | LDD0671 | [4] |
LDCM0355 | AC89 | HCT 116 | C29(0.72) | LDD0672 | [4] |
LDCM0357 | AC90 | HCT 116 | C29(1.09) | LDD0674 | [4] |
LDCM0358 | AC91 | HCT 116 | C29(0.71) | LDD0675 | [4] |
LDCM0359 | AC92 | HCT 116 | C29(0.69) | LDD0676 | [4] |
LDCM0360 | AC93 | HCT 116 | C29(0.78) | LDD0677 | [4] |
LDCM0361 | AC94 | HCT 116 | C29(0.81) | LDD0678 | [4] |
LDCM0362 | AC95 | HCT 116 | C29(0.74) | LDD0679 | [4] |
LDCM0363 | AC96 | HCT 116 | C29(0.71) | LDD0680 | [4] |
LDCM0364 | AC97 | HCT 116 | C29(0.68) | LDD0681 | [4] |
LDCM0365 | AC98 | HCT 116 | C29(0.41) | LDD0682 | [4] |
LDCM0366 | AC99 | HCT 116 | C29(0.65) | LDD0683 | [4] |
LDCM0248 | AKOS034007472 | HCT 116 | C29(0.97) | LDD0565 | [4] |
LDCM0356 | AKOS034007680 | HCT 116 | C29(0.85) | LDD0673 | [4] |
LDCM0275 | AKOS034007705 | HCT 116 | C29(0.77) | LDD0592 | [4] |
LDCM0020 | ARS-1620 | HCC44 | C29(1.02) | LDD2171 | [4] |
LDCM0108 | Chloroacetamide | HeLa | N.A. | LDD0222 | [3] |
LDCM0367 | CL1 | HCT 116 | C29(1.41) | LDD0684 | [4] |
LDCM0368 | CL10 | HCT 116 | C29(0.73) | LDD0685 | [4] |
LDCM0369 | CL100 | HCT 116 | C29(0.94) | LDD0686 | [4] |
LDCM0370 | CL101 | HCT 116 | C29(0.83) | LDD0687 | [4] |
LDCM0371 | CL102 | HCT 116 | C29(0.98) | LDD0688 | [4] |
LDCM0372 | CL103 | HCT 116 | C29(0.94) | LDD0689 | [4] |
LDCM0373 | CL104 | HCT 116 | C29(0.94) | LDD0690 | [4] |
LDCM0374 | CL105 | HCT 116 | C29(0.88) | LDD0691 | [4] |
LDCM0375 | CL106 | HCT 116 | C29(0.84) | LDD0692 | [4] |
LDCM0376 | CL107 | HCT 116 | C29(0.92) | LDD0693 | [4] |
LDCM0377 | CL108 | HCT 116 | C29(0.90) | LDD0694 | [4] |
LDCM0378 | CL109 | HCT 116 | C29(0.83) | LDD0695 | [4] |
LDCM0379 | CL11 | HCT 116 | C29(1.01) | LDD0696 | [4] |
LDCM0380 | CL110 | HCT 116 | C29(0.88) | LDD0697 | [4] |
LDCM0381 | CL111 | HCT 116 | C29(0.86) | LDD0698 | [4] |
LDCM0382 | CL112 | HCT 116 | C29(0.90) | LDD0699 | [4] |
LDCM0383 | CL113 | HCT 116 | C29(0.73) | LDD0700 | [4] |
LDCM0384 | CL114 | HCT 116 | C29(0.80) | LDD0701 | [4] |
LDCM0385 | CL115 | HCT 116 | C29(0.70) | LDD0702 | [4] |
LDCM0386 | CL116 | HCT 116 | C29(0.75) | LDD0703 | [4] |
LDCM0387 | CL117 | HCT 116 | C29(1.02) | LDD0704 | [4] |
LDCM0388 | CL118 | HCT 116 | C29(0.87) | LDD0705 | [4] |
LDCM0389 | CL119 | HCT 116 | C29(0.93) | LDD0706 | [4] |
LDCM0390 | CL12 | HCT 116 | C29(0.90) | LDD0707 | [4] |
LDCM0391 | CL120 | HCT 116 | C29(0.98) | LDD0708 | [4] |
LDCM0392 | CL121 | HCT 116 | C29(0.96) | LDD0709 | [4] |
LDCM0393 | CL122 | HCT 116 | C29(0.80) | LDD0710 | [4] |
LDCM0394 | CL123 | HCT 116 | C29(0.93) | LDD0711 | [4] |
LDCM0395 | CL124 | HCT 116 | C29(0.89) | LDD0712 | [4] |
LDCM0396 | CL125 | HCT 116 | C29(1.02) | LDD0713 | [4] |
LDCM0397 | CL126 | HCT 116 | C29(0.89) | LDD0714 | [4] |
LDCM0398 | CL127 | HCT 116 | C29(0.90) | LDD0715 | [4] |
LDCM0399 | CL128 | HCT 116 | C29(0.95) | LDD0716 | [4] |
LDCM0400 | CL13 | HCT 116 | C29(0.82) | LDD0717 | [4] |
LDCM0401 | CL14 | HCT 116 | C29(0.94) | LDD0718 | [4] |
LDCM0402 | CL15 | HCT 116 | C29(0.79) | LDD0719 | [4] |
LDCM0403 | CL16 | HCT 116 | C29(0.88) | LDD0720 | [4] |
LDCM0404 | CL17 | HCT 116 | C29(0.71) | LDD0721 | [4] |
LDCM0405 | CL18 | HCT 116 | C29(0.71) | LDD0722 | [4] |
LDCM0406 | CL19 | HCT 116 | C29(0.68) | LDD0723 | [4] |
LDCM0407 | CL2 | HCT 116 | C29(1.22) | LDD0724 | [4] |
LDCM0408 | CL20 | HCT 116 | C29(0.64) | LDD0725 | [4] |
LDCM0409 | CL21 | HCT 116 | C29(0.63) | LDD0726 | [4] |
LDCM0410 | CL22 | HCT 116 | C29(0.76) | LDD0727 | [4] |
LDCM0411 | CL23 | HCT 116 | C29(0.74) | LDD0728 | [4] |
LDCM0412 | CL24 | HCT 116 | C29(0.83) | LDD0729 | [4] |
LDCM0413 | CL25 | HCT 116 | C29(0.85) | LDD0730 | [4] |
LDCM0414 | CL26 | HCT 116 | C29(0.76) | LDD0731 | [4] |
LDCM0415 | CL27 | HCT 116 | C29(0.77) | LDD0732 | [4] |
LDCM0416 | CL28 | HCT 116 | C29(0.77) | LDD0733 | [4] |
LDCM0417 | CL29 | HCT 116 | C29(0.66) | LDD0734 | [4] |
LDCM0418 | CL3 | HCT 116 | C29(1.00) | LDD0735 | [4] |
LDCM0419 | CL30 | HCT 116 | C29(0.83) | LDD0736 | [4] |
LDCM0420 | CL31 | HCT 116 | C29(1.01) | LDD0737 | [4] |
LDCM0421 | CL32 | HCT 116 | C29(0.87) | LDD0738 | [4] |
LDCM0422 | CL33 | HCT 116 | C29(0.82) | LDD0739 | [4] |
LDCM0423 | CL34 | HCT 116 | C29(0.98) | LDD0740 | [4] |
LDCM0424 | CL35 | HCT 116 | C29(0.90) | LDD0741 | [4] |
LDCM0425 | CL36 | HCT 116 | C29(1.08) | LDD0742 | [4] |
LDCM0426 | CL37 | HCT 116 | C29(1.05) | LDD0743 | [4] |
LDCM0428 | CL39 | HCT 116 | C29(0.96) | LDD0745 | [4] |
LDCM0429 | CL4 | HCT 116 | C29(0.97) | LDD0746 | [4] |
LDCM0430 | CL40 | HCT 116 | C29(1.01) | LDD0747 | [4] |
LDCM0431 | CL41 | HCT 116 | C29(0.94) | LDD0748 | [4] |
LDCM0432 | CL42 | HCT 116 | C29(1.15) | LDD0749 | [4] |
LDCM0433 | CL43 | HCT 116 | C29(0.91) | LDD0750 | [4] |
LDCM0434 | CL44 | HCT 116 | C29(1.08) | LDD0751 | [4] |
LDCM0435 | CL45 | HCT 116 | C29(1.13) | LDD0752 | [4] |
LDCM0436 | CL46 | HCT 116 | C29(1.18) | LDD0753 | [4] |
LDCM0437 | CL47 | HCT 116 | C29(1.16) | LDD0754 | [4] |
LDCM0438 | CL48 | HCT 116 | C29(1.12) | LDD0755 | [4] |
LDCM0439 | CL49 | HCT 116 | C29(0.98) | LDD0756 | [4] |
LDCM0440 | CL5 | HCT 116 | C29(1.07) | LDD0757 | [4] |
LDCM0441 | CL50 | HCT 116 | C29(1.14) | LDD0758 | [4] |
LDCM0442 | CL51 | HCT 116 | C29(1.15) | LDD0759 | [4] |
LDCM0443 | CL52 | HCT 116 | C29(1.21) | LDD0760 | [4] |
LDCM0444 | CL53 | HCT 116 | C29(1.03) | LDD0761 | [4] |
LDCM0445 | CL54 | HCT 116 | C29(1.11) | LDD0762 | [4] |
LDCM0446 | CL55 | HCT 116 | C29(1.03) | LDD0763 | [4] |
LDCM0447 | CL56 | HCT 116 | C29(0.91) | LDD0764 | [4] |
LDCM0448 | CL57 | HCT 116 | C29(1.19) | LDD0765 | [4] |
LDCM0449 | CL58 | HCT 116 | C29(1.01) | LDD0766 | [4] |
LDCM0450 | CL59 | HCT 116 | C29(1.01) | LDD0767 | [4] |
LDCM0451 | CL6 | HCT 116 | C29(0.79) | LDD0768 | [4] |
LDCM0452 | CL60 | HCT 116 | C29(1.11) | LDD0769 | [4] |
LDCM0453 | CL61 | HCT 116 | C29(0.81) | LDD0770 | [4] |
LDCM0454 | CL62 | HCT 116 | C29(0.84) | LDD0771 | [4] |
LDCM0455 | CL63 | HCT 116 | C29(0.81) | LDD0772 | [4] |
LDCM0456 | CL64 | HCT 116 | C29(0.80) | LDD0773 | [4] |
LDCM0457 | CL65 | HCT 116 | C29(0.87) | LDD0774 | [4] |
LDCM0458 | CL66 | HCT 116 | C29(0.77) | LDD0775 | [4] |
LDCM0459 | CL67 | HCT 116 | C29(0.83) | LDD0776 | [4] |
LDCM0460 | CL68 | HCT 116 | C29(0.74) | LDD0777 | [4] |
LDCM0461 | CL69 | HCT 116 | C29(0.75) | LDD0778 | [4] |
LDCM0462 | CL7 | HCT 116 | C29(1.05) | LDD0779 | [4] |
LDCM0463 | CL70 | HCT 116 | C29(0.77) | LDD0780 | [4] |
LDCM0464 | CL71 | HCT 116 | C29(0.79) | LDD0781 | [4] |
LDCM0465 | CL72 | HCT 116 | C29(0.86) | LDD0782 | [4] |
LDCM0466 | CL73 | HCT 116 | C29(0.79) | LDD0783 | [4] |
LDCM0467 | CL74 | HCT 116 | C29(0.80) | LDD0784 | [4] |
LDCM0469 | CL76 | HCT 116 | C29(0.90) | LDD0786 | [4] |
LDCM0470 | CL77 | HCT 116 | C29(1.09) | LDD0787 | [4] |
LDCM0471 | CL78 | HCT 116 | C29(0.95) | LDD0788 | [4] |
LDCM0472 | CL79 | HCT 116 | C29(0.89) | LDD0789 | [4] |
LDCM0473 | CL8 | HCT 116 | C29(0.93) | LDD0790 | [4] |
LDCM0474 | CL80 | HCT 116 | C29(0.95) | LDD0791 | [4] |
LDCM0475 | CL81 | HCT 116 | C29(1.13) | LDD0792 | [4] |
LDCM0476 | CL82 | HCT 116 | C29(1.08) | LDD0793 | [4] |
LDCM0477 | CL83 | HCT 116 | C29(0.94) | LDD0794 | [4] |
LDCM0478 | CL84 | HCT 116 | C29(1.00) | LDD0795 | [4] |
LDCM0479 | CL85 | HCT 116 | C29(0.90) | LDD0796 | [4] |
LDCM0480 | CL86 | HCT 116 | C29(1.03) | LDD0797 | [4] |
LDCM0481 | CL87 | HCT 116 | C29(1.00) | LDD0798 | [4] |
LDCM0482 | CL88 | HCT 116 | C29(0.99) | LDD0799 | [4] |
LDCM0483 | CL89 | HCT 116 | C29(1.08) | LDD0800 | [4] |
LDCM0484 | CL9 | HCT 116 | C29(0.92) | LDD0801 | [4] |
LDCM0485 | CL90 | HCT 116 | C29(1.54) | LDD0802 | [4] |
LDCM0486 | CL91 | HCT 116 | C29(1.00) | LDD0803 | [4] |
LDCM0487 | CL92 | HCT 116 | C29(1.12) | LDD0804 | [4] |
LDCM0488 | CL93 | HCT 116 | C29(1.22) | LDD0805 | [4] |
LDCM0489 | CL94 | HCT 116 | C29(0.97) | LDD0806 | [4] |
LDCM0490 | CL95 | HCT 116 | C29(0.91) | LDD0807 | [4] |
LDCM0491 | CL96 | HCT 116 | C29(0.98) | LDD0808 | [4] |
LDCM0492 | CL97 | HCT 116 | C29(0.97) | LDD0809 | [4] |
LDCM0493 | CL98 | HCT 116 | C29(0.93) | LDD0810 | [4] |
LDCM0494 | CL99 | HCT 116 | C29(0.94) | LDD0811 | [4] |
LDCM0495 | E2913 | HEK-293T | C29(0.98) | LDD1698 | [9] |
LDCM0213 | Electrophilic fragment 2 | MDA-MB-231 | C29(4.03) | LDD1702 | [2] |
LDCM0468 | Fragment33 | HCT 116 | C29(0.88) | LDD0785 | [4] |
LDCM0427 | Fragment51 | HCT 116 | C29(1.42) | LDD0744 | [4] |
LDCM0022 | KB02 | HEK-293T | C29(0.98) | LDD1492 | [9] |
LDCM0023 | KB03 | HEK-293T | C29(1.02) | LDD1497 | [9] |
LDCM0024 | KB05 | COLO792 | C29(3.17) | LDD3310 | [10] |
LDCM0109 | NEM | HeLa | N.A. | LDD0227 | [3] |
LDCM0503 | Nucleophilic fragment 14b | MDA-MB-231 | C29(0.45) | LDD2096 | [2] |
LDCM0514 | Nucleophilic fragment 20a | MDA-MB-231 | C29(1.41) | LDD2107 | [2] |
LDCM0516 | Nucleophilic fragment 21a | MDA-MB-231 | C29(1.30) | LDD2109 | [2] |
LDCM0525 | Nucleophilic fragment 25b | MDA-MB-231 | C29(0.90) | LDD2118 | [2] |
LDCM0529 | Nucleophilic fragment 27b | MDA-MB-231 | C29(0.47) | LDD2122 | [2] |
LDCM0532 | Nucleophilic fragment 29a | MDA-MB-231 | C29(0.92) | LDD2125 | [2] |
LDCM0550 | Nucleophilic fragment 5a | MDA-MB-231 | C29(1.75) | LDD2144 | [2] |
LDCM0557 | Nucleophilic fragment 8b | MDA-MB-231 | C29(0.38) | LDD2151 | [2] |
LDCM0627 | NUDT7-COV-1 | HEK-293T | C29(0.64) | LDD2206 | [11] |
LDCM0628 | OTUB2-COV-1 | HEK-293T | C29(0.87) | LDD2207 | [11] |
LDCM0131 | RA190 | MM1.R | C29(1.50) | LDD0304 | [12] |
LDCM0021 | THZ1 | HCT 116 | C29(1.02) | LDD2173 | [4] |
The Interaction Atlas With This Target
The Protein(s) Related To This Target
Enzyme
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) | EBP family | Q15125 | |||
TLC domain-containing protein 4 (TLCD4) | TLCD4 family | Q96MV1 |
Transporter and channel
Immunoglobulin
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
B-cell antigen receptor complex-associated protein alpha chain (CD79A) | . | P11912 |
Other
References