Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0112
Competitor Name
W16
Synonyms
4-cyanobenzaldoxime; (E)-4-((Hydroxyimino)methyl)benzonitrile; 52707-54-7; 4-[(E)-hydroxyiminomethyl]benzonitrile; MFCD01205660; AKOS008939715; MS-8977; 4-[(1E)-(hydroxyimino)methyl]benzonitrile; CS-0363109
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 146.15
Lipid-water partition coefficient (xlogp) 1.8
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C8H6N2O
IUPAC Name
4-[(E)-hydroxyiminomethyl]benzonitrile
Canonical SMILES
C1=CC(=CC=C1C=NO)C#N
InChI
InChI=1S/C8H6N2O/c9-5-7-1-3-8(4-2-7)6-10-11/h1-4,6,11H/b10-6+
InChIKey
XUPNOABKAQYYOD-UXBLZVDNSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
W1
 Probe Info  		500 uM Human hepatoblastoma cells (Hep-G2) [1]

Target(s) List of this Competitor

151 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(E3-independent) E2 ubiquitin-conjugating enzyme (UBE2O) LDTP11601 0.69  LDD0239 
3'-5' exoribonuclease 1 (ERI1) LDTP08482 0.80  LDD0239 
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) LDTP02329 0.51  LDD0239 
5'-nucleotidase domain-containing protein 1 (NT5DC1) LDTP17247 1.39  LDD0239 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.64; 0.89  LDD0239 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 1.03  LDD0239 
Actin, alpha skeletal muscle (ACTA1) LDTP05073 1.08; 1.08  LDD0239 
Actin, cytoplasmic 2 (ACTG1) LDTP05059 0.58; 0.66; 0.66 ...  LDD0239 
Activating signal cointegrator 1 complex subunit 3 (ASCC3) LDTP08826 0.52  LDD0239 
Adenosine deaminase (ADA) LDTP01803 1.67  LDD0239 
Aldehyde dehydrogenase 1A1 (ALDH1A1) LDTP01767 1.38  LDD0239 
Aldo-keto reductase family 1 member C2 (AKR1C2) LDTP04543 0.98; 1.24; 1.24 ...  LDD0239 
Aldo-keto reductase family 1 member C3 (AKR1C3) LDTP03976 0.96; 0.96; 1.18 ...  LDD0239 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 1.11  LDD0239 
Alpha-enolase (ENO1) LDTP02159 0.70; 0.70; 0.70 ...  LDD0239 
Alpha-ketoglutarate-dependent dioxygenase FTO (FTO) LDTP11595 0.62  LDD0239 
Aminomethyltransferase, mitochondrial (AMT) LDTP04208 0.80  LDD0239 
AMP deaminase 2 (AMPD2) LDTP05289 0.58  LDD0239 
Androgen-induced gene 1 protein (AIG1) LDTP12697 0.55  LDD0239 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.60; 0.65  LDD0239 
Arsenite methyltransferase (AS3MT) LDTP12188 0.94  LDD0239 
Aspartyl aminopeptidase (DNPEP) LDTP13527 0.52  LDD0239 
ATP-citrate synthase (ACLY) LDTP04561 0.52  LDD0239 
ATP-dependent RNA helicase DDX3Y (DDX3Y) LDTP00664 0.61  LDD0239 
ATP-dependent RNA helicase DDX51 (DDX51) LDTP15453 0.57  LDD0239 
ATP-dependent RNA helicase DHX30 (DHX30) LDTP07946 0.53  LDD0239 
Aurora kinase A (AURKA) LDTP00491 0.72; 0.75  LDD0239 
Baculoviral IAP repeat-containing protein 6 (BIRC6) LDTP12459 0.65  LDD0239 
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) LDTP00717 0.52  LDD0239 
Bifunctional coenzyme A synthase (COASY) LDTP05736 0.66  LDD0239 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 0.65  LDD0239 
Calmodulin-lysine N-methyltransferase (CAMKMT) LDTP08109 0.61  LDD0239 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 1.17  LDD0239 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 0.82  LDD0239 
Caspase-4 (CASP4) LDTP04274 0.74  LDD0239 
Cleavage and polyadenylation specificity factor subunit 3 (CPSF3) LDTP13449 0.63  LDD0239 
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (PDE6C) LDTP04404 0.53  LDD0239 
Cystathionine beta-synthase (CBS) LDTP03753 1.00  LDD0239 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 0.74  LDD0239 
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 0.56  LDD0239 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 6.98  LDD0239 
Dehydrogenase/reductase SDR family member 2, mitochondrial (DHRS2) LDTP05809 0.70; 0.80; 0.80 ...  LDD0239 
DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C) LDTP12539 1.19  LDD0239 
DNA fragmentation factor subunit beta (DFFB) LDTP01394 10.16  LDD0239 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 0.61  LDD0239 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 4.46  LDD0239 
DNA-directed RNA polymerase I subunit RPA34 (POLR1G) LDTP00642 0.58  LDD0239 
DNA-directed RNA polymerase, mitochondrial (POLRMT) LDTP00267 1.00  LDD0239 
Dynamin-1-like protein (DNM1L) LDTP00273 0.58  LDD0239 
Dynamin-2 (DNM2) LDTP04374 0.68  LDD0239 
E3 ubiquitin-protein ligase RNF213 (RNF213) LDTP07283 0.64  LDD0239 
E3 ubiquitin-protein ligase TRIM4 (TRIM4) LDTP11584 1.16  LDD0239 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 0.79  LDD0239 
E3 ubiquitin-protein ligase UBR5 (UBR5) LDTP01495 0.52  LDD0239 
Exosome complex component MTR3 (EXOSC6) LDTP07054 0.59  LDD0239 
Exosome complex component RRP46 (EXOSC5) LDTP12433 0.57  LDD0239 
FAST kinase domain-containing protein 5, mitochondrial (FASTKD5) LDTP07979 0.72; 0.72; 0.81  LDD0239 
Fructosamine-3-kinase (FN3K) LDTP11904 1.25  LDD0239 
Glutamate dehydrogenase 1, mitochondrial (GLUD1) LDTP01768 0.95; 0.95; 1.03  LDD0239 
Glutaredoxin-1 (GLRX) LDTP03786 1.08; 1.10  LDD0239 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.85; 3.97  LDD0239 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 0.94; 0.96; 0.96 ...  LDD0239 
Glycerol-3-phosphate phosphatase (PGP) LDTP00089 1.34  LDD0239 
GTP-binding nuclear protein Ran (RAN) LDTP05007 0.92  LDD0239 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.65; 0.65; 0.68 ...  LDD0239 
Heme oxygenase 2 (HMOX2) LDTP03540 1.50  LDD0239 
Hexokinase-2 (HK2) LDTP04531 0.88  LDD0239 
Histone-lysine N-methyltransferase SETD1A (SETD1A) LDTP00518 0.89  LDD0239 
Holocytochrome c-type synthase (HCCS) LDTP04581 0.62  LDD0239 
Immunity-related GTPase family Q protein (IRGQ) LDTP19838 0.82  LDD0239 
Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK) LDTP00538 1.33  LDD0239 
Integrin-linked protein kinase (ILK) LDTP05859 1.58  LDD0239 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 1.18  LDD0239 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 0.51  LDD0239 
Kinesin-like protein KIFC1 (KIFC1) LDTP11309 0.50  LDD0239 
Large ribosomal subunit protein mL44 (MRPL44) LDTP12098 1.87  LDD0239 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 0.57  LDD0239 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 0.76  LDD0239 
Macrophage migration inhibitory factor (MIF) LDTP02713 0.54  LDD0239 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 1.13  LDD0239 
Mannose-1-phosphate guanyltransferase alpha (GMPPA) LDTP10418 0.53  LDD0239 
Medium-chain acyl-CoA ligase ACSF2, mitochondrial (ACSF2) LDTP10177 1.98  LDD0239 
Methionine aminopeptidase 1 (METAP1) LDTP04565 1.58  LDD0239 
Methylated-DNA--protein-cysteine methyltransferase (MGMT) LDTP02852 1.47  LDD0239 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 0.88  LDD0239 
Mitochondrial coenzyme A diphosphatase NUDT8 (NUDT8) LDTP09598 2.67  LDD0239 
Mitochondrial ribosome-associated GTPase 1 (MTG1) LDTP11177 1.41  LDD0239 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 0.67  LDD0239 
Mitogen-activated protein kinase 8 (MAPK8) LDTP04075 1.20  LDD0239 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 0.89  LDD0239 
mRNA-capping enzyme (RNGTT) LDTP01095 0.68  LDD0239 
Myotubularin-related protein 12 (MTMR12) LDTP11617 1.39  LDD0239 
NAD(P)H dehydrogenase [quinone] 1 (NQO1) LDTP02798 1.16  LDD0239 
NADH-ubiquinone oxidoreductase chain 3 (MT-ND3) LDTP01984 0.59  LDD0239 
Nucleoside diphosphate kinase A (NME1) LDTP02796 0.89; 0.89; 0.91 ...  LDD0239 
Nucleoside diphosphate kinase B (NME2) LDTP03169 1.16; 1.17  LDD0239 
Omega-amidase NIT2 (NIT2) LDTP12428 1.35  LDD0239 
Peroxiredoxin-6 (PRDX6) LDTP03510 0.80  LDD0239 
Persulfide dioxygenase ETHE1, mitochondrial (ETHE1) LDTP01633 1.14  LDD0239 
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (INPP5D) LDTP09895 0.86  LDD0239 
Phosphatidylinositol 4-kinase alpha (PI4KA) LDTP03981 0.55  LDD0239 
Poly(ADP-ribose) glycohydrolase (PARG) LDTP08319 0.58  LDD0239 
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (PLPP6) LDTP08621 0.55  LDD0239 
Pre-rRNA-processing protein TSR1 homolog (TSR1) LDTP14888 2.75  LDD0239 
Probable arginine--tRNA ligase, mitochondrial (RARS2) LDTP07092 0.57; 0.94  LDD0239 
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein (ASMTL) LDTP01647 0.72; 1.35  LDD0239 
Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (USP9Y) LDTP00300 0.58  LDD0239 
Protein disulfide-isomerase (P4HB) LDTP02188 0.92; 1.73; 1.73  LDD0239 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 1.33; 1.38  LDD0239 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 1.33; 1.38  LDD0239 
Protein phosphatase 1G (PPM1G) LDTP00616 0.52  LDD0239 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 0.69  LDD0239 
Putative elongation factor 1-alpha-like 3 (EEF1A1P5) LDTP15029 1.14  LDD0239 
Putative transferase CAF17, mitochondrial (IBA57) LDTP07110 0.54  LDD0239 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 0.68  LDD0239 
Pyruvate kinase PKM (PKM) LDTP02733 1.23  LDD0239 
Regulator of nonsense transcripts 1 (UPF1) LDTP09921 0.96  LDD0239 
Replication factor C subunit 3 (RFC3) LDTP03911 0.60  LDD0239 
Rho-associated protein kinase 2 (ROCK2) LDTP01127 0.71  LDD0239 
Ribosomal biogenesis protein LAS1L (LAS1L) LDTP14074 0.69  LDD0239 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 1.63  LDD0239 
Ribosomal RNA-processing protein 8 (RRP8) LDTP00693 0.50  LDD0239 
rRNA methyltransferase 3, mitochondrial (MRM3) LDTP12215 0.68  LDD0239 
S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) LDTP00890 0.73; 0.73  LDD0239 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 0.67  LDD0239 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 3.54  LDD0239 
Serine--tRNA ligase, mitochondrial (SARS2) LDTP12319 0.60; 0.60  LDD0239 
Serine/threonine-protein kinase Nek9 (NEK9) LDTP09412 0.77; 2.50  LDD0239 
Serine/threonine-protein kinase PLK1 (PLK1) LDTP04555 0.92; 0.92  LDD0239 
Serine/threonine-protein phosphatase CPPED1 (CPPED1) LDTP11107 1.17  LDD0239 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 0.75; 0.79  LDD0239 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 0.67; 0.88; 0.89  LDD0239 
Sulfotransferase 1A4 (SULT1A4) LDTP02431 0.72  LDD0239 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 1.95  LDD0239 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 0.94; 4.16  LDD0239 
TNF receptor-associated factor 2 (TRAF2) LDTP05698 0.53  LDD0239 
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A) LDTP10320 0.75  LDD0239 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 0.63; 0.66; 0.71 ...  LDD0239 
Tudor-interacting repair regulator protein (NUDT16L1) LDTP11111 0.95  LDD0239 
Tyrosine-protein kinase CSK (CSK) LDTP03944 0.77  LDD0239 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 0.54  LDD0239 
Ubiquitin carboxyl-terminal hydrolase 48 (USP48) LDTP08254 1.11  LDD0239 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 0.60  LDD0239 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 1.98  LDD0239 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 1.28  LDD0239 
Unconventional myosin-Vc (MYO5C) LDTP12449 0.72  LDD0239 
UTP--glucose-1-phosphate uridylyltransferase (UGP2) LDTP06649 0.82  LDD0239 
Utrophin (UTRN) LDTP04116 0.54  LDD0239 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 2.46  LDD0239 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 0.67  LDD0239 
Xaa-Pro dipeptidase (PEPD) LDTP02639 0.74  LDD0239 
------------------------------------------------------------------------------------
⏷ Show the Full List of 151 Enzyme
22 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
ADP/ATP translocase 2 (SLC25A5) LDTP02087 1.13  LDD0239 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 0.89  LDD0239 
Autophagy-related protein 9A (ATG9A) LDTP08030 0.57  LDD0239 
Calnexin (CANX) LDTP03405 0.76; 0.83  LDD0239 
Calreticulin (CALR) LDTP03402 0.74; 0.79; 0.96 ...  LDD0239 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 0.97  LDD0239 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 1.12  LDD0239 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.53  LDD0239 
Desmoplakin (DSP) LDTP02815 1.02  LDD0239 
Inositol 1,4,5-trisphosphate receptor type 2 (ITPR2) LDTP06152 0.57  LDD0239 
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) LDTP06153 0.71  LDD0239 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) LDTP13698 1.17  LDD0239 
Nuclear pore complex protein Nup153 (NUP153) LDTP04309 0.95  LDD0239 
Nuclear pore complex protein Nup155 (NUP155) LDTP01295 0.72  LDD0239 
Nuclear pore complex protein Nup160 (NUP160) LDTP05642 1.10  LDD0239 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 1.44  LDD0239 
Oligosaccharyltransferase complex subunit OSTC (OSTC) LDTP12526 1.41  LDD0239 
Pericentriolar material 1 protein (PCM1) LDTP06331 0.81  LDD0239 
Ran-binding protein 6 (RANBP6) LDTP16811 0.78  LDD0239 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 0.54  LDD0239 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 0.52  LDD0239 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 0.59  LDD0239 
------------------------------------------------------------------------------------
⏷ Show the Full List of 22 Transporter and channel
12 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Aryl hydrocarbon receptor (AHR) LDTP03790 0.70  LDD0239 
Enhancer of rudimentary homolog (ERH) LDTP05194 0.94  LDD0239 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 0.74  LDD0239 
Paternally-expressed gene 3 protein (PEG3) LDTP11651 0.70; 0.83  LDD0239 
PHD finger-like domain-containing protein 5A (PHF5A) LDTP08006 1.00  LDD0239 
Signal transducer and activator of transcription 1-alpha/beta (STAT1) LDTP03969 1.06  LDD0239 
SWI/SNF complex subunit SMARCC2 (SMARCC2) LDTP09311 0.58  LDD0239 
Transcription factor SOX-9 (SOX9) LDTP04179 0.99  LDD0239 
Transcriptional enhancer factor TEF-3 (TEAD4) LDTP06415 0.80  LDD0239 
Transcriptional regulator protein Pur-beta (PURB) LDTP10743 0.78  LDD0239 
Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT) LDTP08890 0.52  LDD0239 
Zinc finger protein 516 (ZNF516) LDTP09822 0.71  LDD0239 
------------------------------------------------------------------------------------
⏷ Show the Full List of 12 Transcription factor
1 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Palladin (PALLD) LDTP09680 1.04  LDD0239 
------------------------------------------------------------------------------------
179 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
182 kDa tankyrase-1-binding protein (TNKS1BP1) LDTP11597 0.55  LDD0239 
A-kinase anchor protein 1, mitochondrial (AKAP1) LDTP09837 0.63; 0.89  LDD0239 
A-kinase anchor protein 8 (AKAP8) LDTP00880 0.53  LDD0239 
A-kinase anchor protein 8-like (AKAP8L) LDTP13591 0.76  LDD0239 
Actin nucleation-promoting factor WASL (WASL) LDTP00263 0.80  LDD0239 
Actin-related protein 5 (ACTR5) LDTP12095 1.11  LDD0239 
Acyl-CoA-binding protein (DBI) LDTP02177 0.72; 0.72  LDD0239 
ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3) LDTP12306 0.59; 0.63  LDD0239 
ADP-ribosylation factor-binding protein GGA2 (GGA2) LDTP13414 0.65  LDD0239 
ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL6IP4) LDTP07301 0.84  LDD0239 
Alpha-1-antitrypsin (SERPINA1) LDTP01811 0.85  LDD0239 
Alpha-2-macroglobulin (A2M) LDTP01814 0.55  LDD0239 
Alpha-actinin-4 (ACTN4) LDTP00843 0.53; 1.15  LDD0239 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 1.23  LDD0239 
Anillin (ANLN) LDTP12443 0.87  LDD0239 
Ankycorbin (RAI14) LDTP12963 1.16; 1.16  LDD0239 
Arf-GAP domain and FG repeat-containing protein 2 (AGFG2) LDTP16839 0.57; 2.34  LDD0239 
Bargin (BARGIN) LDTP07832 0.83  LDD0239 
Beta-2-syntrophin (SNTB2) LDTP05864 0.59  LDD0239 
Biogenesis of lysosome-related organelles complex 1 subunit 3 (BLOC1S3) LDTP07624 1.02  LDD0239 
C-Maf-inducing protein (CMIP) LDTP08620 0.60  LDD0239 
Calmin (CLMN) LDTP15754 0.71  LDD0239 
Calponin-2 (CNN2) LDTP10864 0.68  LDD0239 
Catenin alpha-1 (CTNNA1) LDTP03711 1.51  LDD0239 
Catenin beta-1 (CTNNB1) LDTP03712 2.24  LDD0239 
Cell death regulator Aven (AVEN) LDTP16066 0.73  LDD0239 
Cellular retinoic acid-binding protein 2 (CRABP2) LDTP03482 0.88  LDD0239 
Centrosomal protein of 85 kDa (CEP85) LDTP07522 1.11  LDD0239 
Cerebellar degeneration-related protein 2 (CDR2) LDTP05319 0.96  LDD0239 
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6) LDTP06584 0.66  LDD0239 
Cleavage stimulation factor subunit 2 tau variant (CSTF2T) LDTP11718 0.67  LDD0239 
Clustered mitochondria protein homolog (CLUH) LDTP14486 1.40  LDD0239 
Coiled-coil domain-containing protein 71L (CCDC71L) LDTP19760 0.52  LDD0239 
Condensin complex subunit 1 (NCAPD2) LDTP06281 2.25  LDD0239 
Condensin-2 complex subunit D3 (NCAPD3) LDTP03994 0.55  LDD0239 
Conserved oligomeric Golgi complex subunit 1 (COG1) LDTP09549 0.74  LDD0239 
Conserved oligomeric Golgi complex subunit 8 (COG8) LDTP10603 0.86  LDD0239 
Constitutive coactivator of PPAR-gamma-like protein 1 (FAM120A) LDTP12883 1.98  LDD0239 
Corepressor interacting with RBPJ 1 (CIR1) LDTP08354 0.61  LDD0239 
Coronin-1C (CORO1C) LDTP13580 0.54  LDD0239 
Coronin-7 (CORO7) LDTP04798 1.15  LDD0239 
Crk-like protein (CRKL) LDTP04092 1.69  LDD0239 
Cullin-7 (CUL7) LDTP06251 0.79  LDD0239 
Cytochrome c oxidase copper chaperone (COX17) LDTP06030 2.58  LDD0239 
Dedicator of cytokinesis protein 7 (DOCK7) LDTP10613 0.67  LDD0239 
Double-stranded RNA-binding protein Staufen homolog 1 (STAU1) LDTP01677 0.54  LDD0239 
Dynactin subunit 4 (DCTN4) LDTP13402 1.19  LDD0239 
Echinoderm microtubule-associated protein-like 4 (EML4) LDTP12214 0.67  LDD0239 
Elongator complex protein 1 (ELP1) LDTP01511 0.55  LDD0239 
Endoplasmin (HSP90B1) LDTP02734 0.76  LDD0239 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 0.53  LDD0239 
Epidermal growth factor receptor kinase substrate 8 (EPS8) LDTP05696 1.81  LDD0239 
Epidermal growth factor receptor substrate 15 (EPS15) LDTP03982 0.88  LDD0239 
Epiplakin (EPPK1) LDTP04809 0.59  LDD0239 
Eukaryotic translation initiation factor 3 subunit B (EIF3B) LDTP04718 0.58; 1.36  LDD0239 
Exosome complex component RRP40 (EXOSC3) LDTP12434 0.60  LDD0239 
F-actin-capping protein subunit alpha-2 (CAPZA2) LDTP04126 0.71  LDD0239 
Fatty acid-binding protein, liver (FABP1) LDTP02178 0.79; 0.79; 0.79 ...  LDD0239 
Fibrocystin-L (PKHD1L1) LDTP08332 0.58; 0.58  LDD0239 
Gamma-taxilin (TXLNG) LDTP12640 0.53  LDD0239 
Gem-associated protein 6 (GEMIN6) LDTP09690 0.60  LDD0239 
Gephyrin (GPHN) LDTP12448 0.86  LDD0239 
Glycogen debranching enzyme (AGL) LDTP03762 0.94  LDD0239 
Glypican-3 (GPC3) LDTP04439 0.65; 0.74  LDD0239 
Golgin subfamily A member 2 (GOLGA2) LDTP05557 0.62  LDD0239 
GRB10-interacting GYF protein 2 (GIGYF2) LDTP07758 0.57  LDD0239 
HAUS augmin-like complex subunit 8 (HAUS8) LDTP11180 0.81  LDD0239 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 0.67  LDD0239 
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) LDTP00490 0.50; 0.58  LDD0239 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 0.79  LDD0239 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 0.63  LDD0239 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 1.12  LDD0239 
Heterogeneous nuclear ribonucleoprotein L-like (HNRNPLL) LDTP09626 1.63  LDD0239 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 0.61  LDD0239 
Histone H1.2 (H1-2) LDTP02845 0.72; 0.72; 0.75  LDD0239 
Histone H2A type 1-C (H2AC6) LDTP09974 0.61; 0.61; 0.98  LDD0239 
Histone H2A.V (H2AZ2) LDTP07908 1.01  LDD0239 
Histone H2B type 1-L (H2BC13) LDTP11001 0.86; 0.94; 0.97 ...  LDD0239 
Histone H3.2 (H3C15; H3C14; H3C13) LDTP07899 0.83; 0.87; 0.89 ...  LDD0239 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 0.92; 0.93; 0.95 ...  LDD0239 
Inner centromere protein (INCENP) LDTP12432 0.52  LDD0239 
Inner nuclear membrane protein Man1 (LEMD3) LDTP13913 0.66  LDD0239 
Integrator complex subunit 5 (INTS5) LDTP07551 0.59  LDD0239 
Kanadaptin (SLC4A1AP) LDTP15899 0.56  LDD0239 
Keratin, type I cytoskeletal 17 (KRT17) LDTP05424 1.30  LDD0239 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 0.61; 0.67  LDD0239 
Keratin, type II cuticular Hb2 (KRT82) LDTP12579 0.59  LDD0239 
Keratin, type II cytoskeletal 8 (KRT8) LDTP02125 0.53  LDD0239 
KN motif and ankyrin repeat domain-containing protein 1 (KANK1) LDTP06178 0.56; 0.71  LDD0239 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 0.52; 0.60; 0.70 ...  LDD0239 
Large ribosomal subunit protein eL13 (RPL13) LDTP03354 0.94  LDD0239 
Large ribosomal subunit protein eL18 (RPL18) LDTP05509 0.85  LDD0239 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 1.09  LDD0239 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 0.58  LDD0239 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 1.05; 1.05; 1.14  LDD0239 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 1.24  LDD0239 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 1.04  LDD0239 
Large ribosomal subunit protein uL30 (RPL7) LDTP02944 1.11  LDD0239 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.57; 1.12; 1.12  LDD0239 
Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) LDTP03658 0.90; 1.00  LDD0239 
Leucine-rich repeat and IQ domain-containing protein 1 (LRRIQ1) LDTP18175 0.67  LDD0239 
Leucine-rich repeat-containing protein 74B (LRRC74B) LDTP19557 2.14  LDD0239 
LIM domain only protein 7 (LMO7) LDTP09650 1.34  LDD0239 
Lipase maturation factor 2 (LMF2) LDTP15887 1.29  LDD0239 
Lupus La protein (SSB) LDTP02116 0.55  LDD0239 
MAP7 domain-containing protein 1 (MAP7D1) LDTP14910 0.67  LDD0239 
Mediator of RNA polymerase II transcription subunit 15 (MED15) LDTP10771 1.00  LDD0239 
Metallothionein-1E (MT1E) LDTP02050 0.66  LDD0239 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 0.56  LDD0239 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 1.06  LDD0239 
MMS19 nucleotide excision repair protein homolog (MMS19) LDTP10843 0.59  LDD0239 
Multiple myeloma tumor-associated protein 2 (MMTAG2) LDTP11223 0.57  LDD0239 
Myb-binding protein 1A (MYBBP1A) LDTP11079 0.56  LDD0239 
Nucleolar complex protein 2 homolog (NOC2L) LDTP14011 2.33  LDD0239 
Nucleolar protein 16 (NOP16) LDTP16278 0.62  LDD0239 
Nucleolar protein 58 (NOP58) LDTP13925 0.50  LDD0239 
Nucleophosmin (NPM1) LDTP02164 0.65  LDD0239 
NudC domain-containing protein 1 (NUDCD1) LDTP10781 1.02  LDD0239 
Opioid growth factor receptor (OGFR) LDTP16155 0.57  LDD0239 
Peroxisomal membrane protein 11B (PEX11B) LDTP01750 0.88  LDD0239 
Pescadillo homolog (PES1) LDTP00306 0.72  LDD0239 
Phytanoyl-CoA hydroxylase-interacting protein-like (PHYHIPL) LDTP15721 0.60  LDD0239 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 0.62  LDD0239 
Pre-mRNA-splicing factor 38B (PRPF38B) LDTP17266 0.76  LDD0239 
Prelamin-A/C (LMNA) LDTP01932 0.62  LDD0239 
Profilin-1 (PFN1) LDTP02218 1.17  LDD0239 
Programmed cell death protein 4 (PDCD4) LDTP06881 0.55  LDD0239 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 2.50  LDD0239 
Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) LDTP08707 0.67  LDD0239 
Proline-rich protein 36 (PRR36) LDTP19969 2.08  LDD0239 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 0.62  LDD0239 
Protein HGH1 homolog (HGH1) LDTP18309 0.92  LDD0239 
Protein IWS1 homolog (IWS1) LDTP10822 0.56  LDD0239 
Protein lin-28 homolog B (LIN28B) LDTP07784 0.70  LDD0239 
Protein LRATD2 (LRATD2) LDTP15761 0.98; 0.98  LDD0239 
Protein NCBP2AS2 (NCBP2AS2) LDTP19472 0.55  LDD0239 
Protein phosphatase 1 regulatory subunit 3C (PPP1R3C) LDTP13763 1.28  LDD0239 
Protein RCC2 (RCC2) LDTP13020 0.53  LDD0239 
Protein sprouty homolog 4 (SPRY4) LDTP11577 0.55  LDD0239 
Protein TMEPAI (PMEPA1) LDTP10042 0.62; 0.65  LDD0239 
Protein TOPAZ1 (TOPAZ1) LDTP17767 0.91  LDD0239 
PSME3-interacting protein (PSME3IP1) LDTP11654 0.67  LDD0239 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 1.10  LDD0239 
Reticulon-4 (RTN4) LDTP12412 0.60  LDD0239 
Rho guanine nucleotide exchange factor 12 (ARHGEF12) LDTP12924 0.80  LDD0239 
Rho guanine nucleotide exchange factor 2 (ARHGEF2) LDTP09950 0.65  LDD0239 
Ribosomal RNA processing protein 1 homolog A (RRP1) LDTP04729 1.68  LDD0239 
Ribosomal RNA processing protein 1 homolog B (RRP1B) LDTP06182 1.22  LDD0239 
Ribosome biogenesis protein BRX1 homolog (BRIX1) LDTP15609 0.52  LDD0239 
RING finger protein 141 (RNF141) LDTP09606 0.53; 0.53  LDD0239 
RNA binding motif protein, X-linked-like-1 (RBMXL1) LDTP18146 0.93  LDD0239 
RRP12-like protein (RRP12) LDTP14980 0.63  LDD0239 
SAC3 domain-containing protein 1 (SAC3D1) LDTP14373 1.39  LDD0239 
Scaffold attachment factor B2 (SAFB2) LDTP06054 0.69; 1.12  LDD0239 
Shootin-1 (SHTN1) LDTP00019 0.92  LDD0239 
Small ribosomal subunit protein mS40 (MRPS18B) LDTP14215 0.63; 0.63  LDD0239 
Small ribosomal subunit protein uS15 (RPS13) LDTP04974 0.96  LDD0239 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 1.22  LDD0239 
Small ribosomal subunit protein uS4 (RPS9) LDTP04109 0.95; 1.07  LDD0239 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 1.13  LDD0239 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 0.56  LDD0239 
Src substrate cortactin (CTTN) LDTP06094 0.51  LDD0239 
STING ER exit protein (STEEP1) LDTP11964 1.23  LDD0239 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 1.04; 1.07; 1.10 ...  LDD0239 
Target of EGR1 protein 1 (TOE1) LDTP10354 1.48  LDD0239 
TBC1 domain family member 13 (TBC1D13) LDTP16107 0.65; 0.68  LDD0239 
TRAF family member-associated NF-kappa-B activator (TANK) LDTP09901 0.72  LDD0239 
Transcription termination factor 4, mitochondrial (MTERF4) LDTP08132 0.73  LDD0239 
Transducin beta-like protein 2 (TBL2) LDTP16285 0.84  LDD0239 
tRNA-splicing endonuclease subunit Sen15 (TSEN15) LDTP09632 0.61  LDD0239 
TRPM8 channel-associated factor 1 (TCAF1) LDTP14041 0.76; 0.76  LDD0239 
Ubiquitin-ribosomal protein eL40 fusion protein (UBA52) LDTP05034 1.56; 1.70  LDD0239 
UPF0696 protein C11orf68 (C11orf68) LDTP11866 0.55  LDD0239 
von Willebrand factor A domain-containing protein 8 (VWA8) LDTP00057 1.11  LDD0239 
WD repeat and coiled-coil-containing protein (WDCP) LDTP11995 0.80  LDD0239 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.10  LDD0239 
Zinc finger CCCH domain-containing protein 7B (ZC3H7B) LDTP13245 1.58  LDD0239 
Zinc finger CCHC domain-containing protein 8 (ZCCHC8) LDTP07496 0.80  LDD0239 
Zinc finger RNA-binding protein (ZFR) LDTP15762 0.90  LDD0239 
------------------------------------------------------------------------------------
⏷ Show the Full List of 179 Other

Full Information of The Labelling Profiles of This Competitor

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 500 uM
Quantitative Method SILAC
Competitor Name W16
Competitor Concentration 500 uM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Liver
Disease Model Hepatoblastoma [ICD-11:DB91]
Model Name Human hepatoblastoma cells (Hep-G2)
Interaction Atlas ID  LDD0239  Download The Altas

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.