Details of the Target

General Information of Target

Target ID LDTP15754
Target Name Calmin (CLMN)
Gene Name CLMN
Gene ID 79789
Synonyms
KIAA1188; Calmin; Calponin-like transmembrane domain protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGRNQRKAPQRLERPGRPASGEQESGSASADGAPSRERRSDRGQADRAKPAAEPATAGGQ
GTPGGRRKPTAEGNGGCRRPGAGLSPKAQERQSNAQRQGRGPRGGRGGRLEEGSLSGGEE
LGGRRRRKRKDKGPSARRGRRTPRSLNGDTSGGDGGSSCPDSETREAQESGSQRGTAREL
RPTPEPTDMGSEGTKTGPESALEPSSDGLDSDWPHADTRGREGSSGTGPLGASEHSGGDS
DSSPLGTGPGRGSRAAMASRTFEDSSRAPRDTGPAKDASDNRAQRGAEPETMQASTARAP
RHQVGKAVGQVPAAAGEGEAGAAAGAGPEDPAPLAALLVVRRLLARPPPGAASQAVGPRR
AGLKERLLSVARALGLLRWLRRRLRLRRRPPEGEGQGTGPRASEGWGRRKPDEGRGHGRG
SKGRGRGKADEGRGHERGDEGRGRGKADEGRGHERGYEGRGCGKADEGRGHERGDEGRDH
QRGYEGWGREPGLRHRLALRLAGLAGLGGMPRASPGGRSPQVPTSPVPGDPFDQEDETPD
PKFAVVFPRIHRAGRASSSRSSEEASADAPTGEGRGWPRAGVGGHSEGCRTSGEGVSGLR
RGSLLAPTAPDGPSLDESGSSSEAELETLNDEPPVRWAQGSGPHEGPRLGAAVLLPRLSL
ETRLQQEGDPGLRGSLRELWEPEDEDEAVLERDLELSLRPGLEAPPFPGAKGRSLGDGLE
DMEDLARLRLVCDSSVLLCLKKRFHLGRIYTFGGPVLLVLNPHRSLPLFSPEVQASYHPR
KALSTTPHIFAIVASAYDLAQNTGQDPCILLCSSHCSGHSGSGKTEAAKKIMQFLSSLEQ
DQTGNRECQVEDMLPILSSFGHAKTILNANASRFGQVFCLYLQQGVIVGASVSHYLLETS
RVVFQAQAERSFHVFYKLLAGLDSIERERLSLQGPETYYYLNQGQACRLQGKEDAQDFEG
LLKALQGLGLCPEELNAVWAVLAAILQLGNICFSSSERESQEVAAVSSWAEIHTAARLLR
VPPECLEGAVTRRVTETPYGQVSRSLPVESAFDARDALAKALYSRLFHRLLRRTNARLAP
PGEGGSIGTVTVVDAYGFEALRVNGLEQLCNNLASERLQLFSSQMLLAQEEEECRRELLS
WVPVPQPPRESCLDLLVDQPHSLLSILDAQTWLSQATDHTFLQKSHYHHGDHPSYAKPRL
PLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQLVGSLFQEAEPQSRGGR
GRPTLASRFQQALEDLIARLGRSHVYFIQCLTPNPGKLPGLFDVGHVTEQLHQAAILEAV
GTRSANFPVRVPFEAFLASFQALGSEGQEDLSDREKCGAVLSQVLGAESPLYHLGATKVL
LQEQGWQRLEELRDQQRSQALVDLHRSFHTCISRQRVLPRMQARMRGFQARKRYLRRRAA
LGQLNTILLVAQPLLQRRQRLQLGRWQGWHSSERALERVPSMELGRLEIPAELAVMLKTA
ESHRDALAGSITECLPPEVPARPSLTLPADIDLFPFSSFVAIGFQEPSLPRPGQPLAKPL
TQLDGDNPQRALDINKVMLRLLGDGSLESWQRQIMGAYLVRQGQCRPGLRNELFSQLVAQ
LWQNPDEQQSQRGWALMAVLLSAFPPLPVLQKPLLKFVSDQAPRGMAALCQHKLLGALEQ
SQLASGATRAHPPTQLEWLAGWRRGRMALDVFTFSEECYSAEVESWTTGEQLAGWILQSR
GLEAPPRGWSVSLHSRDAWQDLAGCDFVLDLISQTEDLGDPARPRSYPITPLGSAEAIPL
APGIQAPSLPPGPPPGPAPTLPSRDHTGEVQRSGSLDGFLDQIFQPVISSGLSDLEQSWA
LSSRMKGGGAIGPTQQGYPMVYPGMIQMPAYQPGMVPAPMPMMPAMGTVPAMPAMVVPPQ
PPLPSLDAGQLAVQQQNFIQQQALILAQQMTAQAMSLSLEQQMQQRQQQARASEAASQAS
PSAVTSKPRKPPTPPEKPQRDLGSEGGCLRETSEEAEDRPYQPKSFQQKRNYFQRMGQPQ
ITVRTMKPPAKVHIPQGEAQEEEEEEEEEEEQEEQEVETRAVPSPPPPPIVKKPLKQGGA
KAPKEAEAEPAKETAAKGHGQGPAQGRGTVVRSSDSKPKRPQPSREIGNIIRMYQSRPGP
VPVPVQPSRPPKAFLRKIDPKDEALAKLGINGAHSSPPMLSPSPGKGPPPAVAPRPKAPL
QLGPSSSIKEKQGPLLDLFGQKLPIAHTPPPPPAPPLPLPEDPGTLSAERRCLTQPVEDQ
GVSTQLLAPSGSVCFSYTGTPWKLFLRKEVFYPRENFSHPYYLRLLCEQILRDTFSESCI
RISQNERRKMKDLLGGLEVDLDSLTTTEDSVKKRIVVAARDNWANYFSRFFPVSGESGSD
VQLLAVSHRGLRLLKVTQGPGLRPDQLKILCSYSFAEVLGVECRGGSTLELSLKSEQLVL
HTARARAIEALVELFLNELKKDSGYVIALRSYITDNCSLLSFHRGDLIKLLPVATLEPGW
QFGSAGGRSGLFPADIVQPAAAPDFSFSKEQRSGWHKGQLSNGEPGLARWDRASERPAHP
WSQAHSDDSEATSLSSVAYAFLPDSHSYTMQEFARRYFRRSQALLGQTDGGAAGKDTDSL
VQYTKAPIQESLLSLSDDVSKLAVASFLALMRFMGDQSKPRGKDEMDLLYELLKLCQQEK
LRDEIYCQVIKQVTGHPRPEHCTRGWSFLSLLTGFFPPSTRLMPYLTKFLQDSGPSQELA
RSSQEHLQRTVKYGGRRRMPPPGEMKAFLKGQAIRLLLIHLPGGVDYRTNIQTFTVAAEV
QEELCRQMGITEPQEVQEFALFLIKEKSQLVRPLQPAEYLNSVVVDQDVSLHSRRLHWET
PLHFDNSTYISTHYSQVLWDYLQGKLPVSAKADAQLARLAALQHLSKANRNTPSGQDLLA
YVPKQLQRQVNTASIKNLMGQELRRLEGHSPQEAQISFIEAMSQLPLFGYTVYGVLRVSM
QALSGPTLLGLNRQHLILMDPSSQSLYCRIALKSLQRLHLLSPLEEKGPPGLEVNYGSAD
NPQTIWFELPQAQELLYTTVFLIDSSASCTEWPSIN
Target Bioclass
Other
Subcellular location
Membrane
Uniprot ID
Q96JQ2
Ensemble ID
ENST00000298912.9
HGNC ID
HGNC:19972

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 8 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
AHL-Pu-1
 Probe Info  		C438(2.13)  LDD0171  [2]
DBIA
 Probe Info  		C445(1.04)  LDD0531  [3]
IA-alkyne
 Probe Info  		C438(0.00); C445(0.00)  LDD0162  [4]
NAIA_4
 Probe Info  		N.A.  LDD2226  [5]
NAIA_5
 Probe Info  		C438(0.00); C353(0.00)  LDD2224  [5]
IPM
 Probe Info  		N.A.  LDD0005  [6]
W1
 Probe Info  		N.A.  LDD0236  [7]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA DM93 C438(2.13)  LDD0171  [2]
 LDCM0214  AC1 HCT 116 C445(1.04)  LDD0531  [3]
 LDCM0215  AC10 HEK-293T C353(0.90)  LDD1508  [8]
 LDCM0216  AC100 HCT 116 C445(0.56)  LDD0533  [3]
 LDCM0217  AC101 HCT 116 C445(0.54)  LDD0534  [3]
 LDCM0218  AC102 HCT 116 C445(0.58)  LDD0535  [3]
 LDCM0219  AC103 HCT 116 C445(0.67)  LDD0536  [3]
 LDCM0220  AC104 HCT 116 C445(0.74)  LDD0537  [3]
 LDCM0221  AC105 HCT 116 C445(0.61)  LDD0538  [3]
 LDCM0222  AC106 HCT 116 C445(0.59)  LDD0539  [3]
 LDCM0223  AC107 HCT 116 C445(0.60)  LDD0540  [3]
 LDCM0224  AC108 HCT 116 C445(0.48)  LDD0541  [3]
 LDCM0225  AC109 HCT 116 C445(0.33)  LDD0542  [3]
 LDCM0226  AC11 HEK-293T C353(1.02)  LDD1509  [8]
 LDCM0227  AC110 HCT 116 C445(0.54)  LDD0544  [3]
 LDCM0228  AC111 HCT 116 C445(0.73)  LDD0545  [3]
 LDCM0229  AC112 HCT 116 C445(0.55)  LDD0546  [3]
 LDCM0230  AC113 HCT 116 C445(0.94)  LDD0547  [3]
 LDCM0231  AC114 HCT 116 C445(1.09)  LDD0548  [3]
 LDCM0232  AC115 HCT 116 C445(0.96)  LDD0549  [3]
 LDCM0233  AC116 HCT 116 C445(1.04)  LDD0550  [3]
 LDCM0234  AC117 HCT 116 C445(0.93)  LDD0551  [3]
 LDCM0235  AC118 HCT 116 C445(0.81)  LDD0552  [3]
 LDCM0236  AC119 HCT 116 C445(0.95)  LDD0553  [3]
 LDCM0237  AC12 HEK-293T C353(1.04)  LDD1510  [8]
 LDCM0238  AC120 HCT 116 C445(0.91)  LDD0555  [3]
 LDCM0239  AC121 HCT 116 C445(0.77)  LDD0556  [3]
 LDCM0240  AC122 HCT 116 C445(0.90)  LDD0557  [3]
 LDCM0241  AC123 HCT 116 C445(0.79)  LDD0558  [3]
 LDCM0242  AC124 HCT 116 C445(0.79)  LDD0559  [3]
 LDCM0243  AC125 HCT 116 C445(0.89)  LDD0560  [3]
 LDCM0244  AC126 HCT 116 C445(0.93)  LDD0561  [3]
 LDCM0245  AC127 HCT 116 C445(0.84)  LDD0562  [3]
 LDCM0259  AC14 HEK-293T C353(0.91); C445(0.99)  LDD1512  [8]
 LDCM0263  AC143 HCT 116 C445(1.12)  LDD0580  [3]
 LDCM0264  AC144 HCT 116 C445(0.67)  LDD0581  [3]
 LDCM0265  AC145 HCT 116 C445(1.44)  LDD0582  [3]
 LDCM0266  AC146 HCT 116 C445(1.61)  LDD0583  [3]
 LDCM0267  AC147 HCT 116 C445(1.00)  LDD0584  [3]
 LDCM0268  AC148 HCT 116 C445(1.19)  LDD0585  [3]
 LDCM0269  AC149 HCT 116 C445(1.33)  LDD0586  [3]
 LDCM0270  AC15 HEK-293T C353(1.01)  LDD1513  [8]
 LDCM0271  AC150 HCT 116 C445(0.90)  LDD0588  [3]
 LDCM0272  AC151 HCT 116 C445(1.22)  LDD0589  [3]
 LDCM0273  AC152 HCT 116 C445(1.40)  LDD0590  [3]
 LDCM0274  AC153 HCT 116 C445(1.42)  LDD0591  [3]
 LDCM0621  AC154 HCT 116 C445(1.27)  LDD2158  [3]
 LDCM0622  AC155 HCT 116 C445(1.56)  LDD2159  [3]
 LDCM0623  AC156 HCT 116 C445(1.62)  LDD2160  [3]
 LDCM0624  AC157 HCT 116 C445(1.20)  LDD2161  [3]
 LDCM0276  AC17 HEK-293T C353(1.05)  LDD1515  [8]
 LDCM0277  AC18 HEK-293T C353(1.05)  LDD1516  [8]
 LDCM0278  AC19 HEK-293T C353(1.11)  LDD1517  [8]
 LDCM0279  AC2 HCT 116 C445(1.06)  LDD0596  [3]
 LDCM0280  AC20 HEK-293T C353(0.96)  LDD1519  [8]
 LDCM0281  AC21 HEK-293T C353(0.98)  LDD1520  [8]
 LDCM0282  AC22 HEK-293T C353(0.96); C445(1.03)  LDD1521  [8]
 LDCM0283  AC23 HEK-293T C353(1.00)  LDD1522  [8]
 LDCM0284  AC24 HEK-293T C353(1.06); C445(1.07)  LDD1523  [8]
 LDCM0285  AC25 HEK-293T C353(1.01)  LDD1524  [8]
 LDCM0286  AC26 HEK-293T C353(1.00)  LDD1525  [8]
 LDCM0287  AC27 HEK-293T C353(1.05)  LDD1526  [8]
 LDCM0288  AC28 HEK-293T C353(1.01)  LDD1527  [8]
 LDCM0289  AC29 HEK-293T C353(1.02)  LDD1528  [8]
 LDCM0290  AC3 HCT 116 C445(1.19)  LDD0607  [3]
 LDCM0291  AC30 HEK-293T C353(0.97); C445(0.90)  LDD1530  [8]
 LDCM0292  AC31 HEK-293T C353(0.96)  LDD1531  [8]
 LDCM0293  AC32 HEK-293T C353(1.01); C445(0.92)  LDD1532  [8]
 LDCM0294  AC33 HEK-293T C353(1.00)  LDD1533  [8]
 LDCM0295  AC34 HEK-293T C353(1.13)  LDD1534  [8]
 LDCM0296  AC35 HEK-293T C353(1.06)  LDD1535  [8]
 LDCM0297  AC36 HEK-293T C353(1.12)  LDD1536  [8]
 LDCM0298  AC37 HEK-293T C353(0.95)  LDD1537  [8]
 LDCM0299  AC38 HEK-293T C353(0.98); C445(0.85)  LDD1538  [8]
 LDCM0300  AC39 HEK-293T C353(1.00)  LDD1539  [8]
 LDCM0301  AC4 HCT 116 C445(1.15)  LDD0618  [3]
 LDCM0302  AC40 HEK-293T C353(1.04); C445(0.93)  LDD1541  [8]
 LDCM0303  AC41 HEK-293T C353(0.99)  LDD1542  [8]
 LDCM0304  AC42 HEK-293T C353(1.19)  LDD1543  [8]
 LDCM0305  AC43 HEK-293T C353(1.06)  LDD1544  [8]
 LDCM0306  AC44 HEK-293T C353(1.11)  LDD1545  [8]
 LDCM0307  AC45 HEK-293T C353(1.02)  LDD1546  [8]
 LDCM0308  AC46 HEK-293T C353(0.96); C445(1.06)  LDD1547  [8]
 LDCM0309  AC47 HEK-293T C353(1.01)  LDD1548  [8]
 LDCM0310  AC48 HEK-293T C353(0.99); C445(1.03)  LDD1549  [8]
 LDCM0311  AC49 HEK-293T C353(1.00)  LDD1550  [8]
 LDCM0312  AC5 HCT 116 C445(1.02)  LDD0629  [3]
 LDCM0313  AC50 HEK-293T C353(0.94)  LDD1552  [8]
 LDCM0314  AC51 HEK-293T C353(1.01)  LDD1553  [8]
 LDCM0315  AC52 HEK-293T C353(1.08)  LDD1554  [8]
 LDCM0316  AC53 HEK-293T C353(0.96)  LDD1555  [8]
 LDCM0317  AC54 HEK-293T C353(0.93); C445(0.98)  LDD1556  [8]
 LDCM0318  AC55 HEK-293T C353(1.03)  LDD1557  [8]
 LDCM0319  AC56 HEK-293T C353(1.01); C445(0.98)  LDD1558  [8]
 LDCM0320  AC57 HCT 116 C445(1.45)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C445(0.77)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C445(0.76)  LDD0639  [3]
 LDCM0323  AC6 HEK-293T C353(0.92); C445(0.91)  LDD1562  [8]
 LDCM0324  AC60 HCT 116 C445(0.62)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C445(0.87)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C445(0.77)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C445(0.73)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C445(0.73)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C445(0.57)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C445(0.34)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C445(0.41)  LDD0648  [3]
 LDCM0332  AC68 HCT 116 C445(1.05)  LDD0649  [3]
 LDCM0333  AC69 HCT 116 C445(1.39)  LDD0650  [3]
 LDCM0334  AC7 HEK-293T C353(1.06)  LDD1568  [8]
 LDCM0335  AC70 HCT 116 C445(1.18)  LDD0652  [3]
 LDCM0336  AC71 HCT 116 C445(0.92)  LDD0653  [3]
 LDCM0337  AC72 HCT 116 C445(1.34)  LDD0654  [3]
 LDCM0338  AC73 HCT 116 C445(1.58)  LDD0655  [3]
 LDCM0339  AC74 HCT 116 C445(1.16)  LDD0656  [3]
 LDCM0340  AC75 HCT 116 C445(1.21)  LDD0657  [3]
 LDCM0341  AC76 HCT 116 C445(1.03)  LDD0658  [3]
 LDCM0342  AC77 HCT 116 C445(1.17)  LDD0659  [3]
 LDCM0343  AC78 HCT 116 C445(1.14)  LDD0660  [3]
 LDCM0344  AC79 HCT 116 C445(1.04)  LDD0661  [3]
 LDCM0345  AC8 HEK-293T C353(1.02); C445(0.93)  LDD1569  [8]
 LDCM0346  AC80 HCT 116 C445(1.21)  LDD0663  [3]
 LDCM0347  AC81 HCT 116 C445(0.71)  LDD0664  [3]
 LDCM0348  AC82 HCT 116 C445(1.57)  LDD0665  [3]
 LDCM0349  AC83 HCT 116 C445(1.30)  LDD0666  [3]
 LDCM0350  AC84 HCT 116 C445(1.02)  LDD0667  [3]
 LDCM0351  AC85 HCT 116 C445(1.07)  LDD0668  [3]
 LDCM0352  AC86 HCT 116 C445(1.17)  LDD0669  [3]
 LDCM0353  AC87 HCT 116 C445(1.32)  LDD0670  [3]
 LDCM0354  AC88 HCT 116 C445(1.20)  LDD0671  [3]
 LDCM0355  AC89 HCT 116 C445(1.27)  LDD0672  [3]
 LDCM0357  AC90 HCT 116 C445(1.17)  LDD0674  [3]
 LDCM0358  AC91 HCT 116 C445(1.41)  LDD0675  [3]
 LDCM0359  AC92 HCT 116 C445(1.26)  LDD0676  [3]
 LDCM0360  AC93 HCT 116 C445(1.03)  LDD0677  [3]
 LDCM0361  AC94 HCT 116 C445(1.05)  LDD0678  [3]
 LDCM0362  AC95 HCT 116 C445(1.22)  LDD0679  [3]
 LDCM0363  AC96 HCT 116 C445(1.11)  LDD0680  [3]
 LDCM0364  AC97 HCT 116 C445(1.35)  LDD0681  [3]
 LDCM0365  AC98 HCT 116 C445(0.90)  LDD0682  [3]
 LDCM0366  AC99 HCT 116 C445(0.44)  LDD0683  [3]
 LDCM0248  AKOS034007472 HEK-293T C353(0.95)  LDD1511  [8]
 LDCM0356  AKOS034007680 HEK-293T C353(0.98)  LDD1570  [8]
 LDCM0275  AKOS034007705 HEK-293T C353(0.97); C445(0.98)  LDD1514  [8]
 LDCM0156  Aniline NCI-H1299 11.88  LDD0403  [1]
 LDCM0632  CL-Sc Hep-G2 C353(20.00); C438(0.55)  LDD2227  [5]
 LDCM0367  CL1 HCT 116 C445(0.63)  LDD0684  [3]
 LDCM0368  CL10 HCT 116 C445(0.73)  LDD0685  [3]
 LDCM0369  CL100 HCT 116 C445(1.25)  LDD0686  [3]
 LDCM0370  CL101 HEK-293T C353(1.07)  LDD1574  [8]
 LDCM0371  CL102 HEK-293T C353(0.91)  LDD1575  [8]
 LDCM0372  CL103 HEK-293T C353(1.04)  LDD1576  [8]
 LDCM0373  CL104 HEK-293T C353(1.01)  LDD1577  [8]
 LDCM0374  CL105 HEK-293T C353(1.04)  LDD1578  [8]
 LDCM0375  CL106 HEK-293T C353(0.98)  LDD1579  [8]
 LDCM0376  CL107 HEK-293T C353(1.04)  LDD1580  [8]
 LDCM0377  CL108 HEK-293T C353(1.06)  LDD1581  [8]
 LDCM0378  CL109 HEK-293T C353(0.94)  LDD1582  [8]
 LDCM0379  CL11 HCT 116 C445(0.98)  LDD0696  [3]
 LDCM0380  CL110 HEK-293T C353(0.92)  LDD1584  [8]
 LDCM0381  CL111 HEK-293T C353(1.07)  LDD1585  [8]
 LDCM0382  CL112 HEK-293T C353(1.15)  LDD1586  [8]
 LDCM0383  CL113 HEK-293T C353(1.00)  LDD1587  [8]
 LDCM0384  CL114 HEK-293T C353(0.93)  LDD1588  [8]
 LDCM0385  CL115 HEK-293T C353(1.09)  LDD1589  [8]
 LDCM0386  CL116 HEK-293T C353(1.08)  LDD1590  [8]
 LDCM0387  CL117 HEK-293T C353(1.06)  LDD1591  [8]
 LDCM0388  CL118 HEK-293T C353(0.91)  LDD1592  [8]
 LDCM0389  CL119 HEK-293T C353(1.07)  LDD1593  [8]
 LDCM0390  CL12 HCT 116 C445(0.95)  LDD0707  [3]
 LDCM0391  CL120 HEK-293T C353(1.07)  LDD1595  [8]
 LDCM0392  CL121 HEK-293T C353(1.03)  LDD1596  [8]
 LDCM0393  CL122 HEK-293T C353(0.92)  LDD1597  [8]
 LDCM0394  CL123 HEK-293T C353(0.87)  LDD1598  [8]
 LDCM0395  CL124 HEK-293T C353(1.05)  LDD1599  [8]
 LDCM0396  CL125 HCT 116 C445(0.53)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C445(0.54)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C445(0.61)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C445(0.67)  LDD0716  [3]
 LDCM0400  CL13 HCT 116 C445(0.75)  LDD0717  [3]
 LDCM0401  CL14 HCT 116 C445(1.09)  LDD0718  [3]
 LDCM0402  CL15 HCT 116 C445(0.71)  LDD0719  [3]
 LDCM0403  CL16 HEK-293T C353(1.06)  LDD1607  [8]
 LDCM0404  CL17 HEK-293T C353(0.97)  LDD1608  [8]
 LDCM0405  CL18 HEK-293T C353(0.87)  LDD1609  [8]
 LDCM0406  CL19 HEK-293T C353(1.02)  LDD1610  [8]
 LDCM0407  CL2 HCT 116 C445(0.77)  LDD0724  [3]
 LDCM0408  CL20 HEK-293T C353(1.14)  LDD1612  [8]
 LDCM0409  CL21 HEK-293T C353(0.90)  LDD1613  [8]
 LDCM0410  CL22 HEK-293T C353(0.95); C445(1.22)  LDD1614  [8]
 LDCM0411  CL23 HEK-293T C353(1.13)  LDD1615  [8]
 LDCM0412  CL24 HEK-293T C353(1.01); C445(1.09)  LDD1616  [8]
 LDCM0413  CL25 HEK-293T C353(0.90)  LDD1617  [8]
 LDCM0414  CL26 HEK-293T C353(0.89)  LDD1618  [8]
 LDCM0415  CL27 HEK-293T C353(0.96)  LDD1619  [8]
 LDCM0416  CL28 HEK-293T C353(0.97)  LDD1620  [8]
 LDCM0417  CL29 HEK-293T C353(1.05)  LDD1621  [8]
 LDCM0418  CL3 HCT 116 C445(0.82)  LDD0735  [3]
 LDCM0419  CL30 HEK-293T C353(1.05)  LDD1623  [8]
 LDCM0420  CL31 HEK-293T C353(1.12)  LDD1624  [8]
 LDCM0421  CL32 HEK-293T C353(1.05)  LDD1625  [8]
 LDCM0422  CL33 HEK-293T C353(0.92)  LDD1626  [8]
 LDCM0423  CL34 HEK-293T C353(0.96); C445(1.18)  LDD1627  [8]
 LDCM0424  CL35 HEK-293T C353(1.04)  LDD1628  [8]
 LDCM0425  CL36 HEK-293T C353(1.03); C445(1.16)  LDD1629  [8]
 LDCM0426  CL37 HEK-293T C353(0.83)  LDD1630  [8]
 LDCM0428  CL39 HEK-293T C353(1.06)  LDD1632  [8]
 LDCM0429  CL4 HCT 116 C445(0.65)  LDD0746  [3]
 LDCM0430  CL40 HEK-293T C353(1.02)  LDD1634  [8]
 LDCM0431  CL41 HEK-293T C353(1.00)  LDD1635  [8]
 LDCM0432  CL42 HEK-293T C353(1.20)  LDD1636  [8]
 LDCM0433  CL43 HEK-293T C353(1.02)  LDD1637  [8]
 LDCM0434  CL44 HEK-293T C353(1.12)  LDD1638  [8]
 LDCM0435  CL45 HEK-293T C353(0.98)  LDD1639  [8]
 LDCM0436  CL46 HCT 116 C445(1.01)  LDD0753  [3]
 LDCM0437  CL47 HCT 116 C445(1.20)  LDD0754  [3]
 LDCM0438  CL48 HCT 116 C445(0.89)  LDD0755  [3]
 LDCM0439  CL49 HCT 116 C445(0.96)  LDD0756  [3]
 LDCM0440  CL5 HCT 116 C445(0.89)  LDD0757  [3]
 LDCM0441  CL50 HCT 116 C445(1.07)  LDD0758  [3]
 LDCM0442  CL51 HCT 116 C445(1.04)  LDD0759  [3]
 LDCM0443  CL52 HCT 116 C445(1.09)  LDD0760  [3]
 LDCM0444  CL53 HCT 116 C445(1.07)  LDD0761  [3]
 LDCM0445  CL54 HCT 116 C445(0.96)  LDD0762  [3]
 LDCM0446  CL55 HCT 116 C445(1.04)  LDD0763  [3]
 LDCM0447  CL56 HCT 116 C445(0.85)  LDD0764  [3]
 LDCM0448  CL57 HCT 116 C445(0.89)  LDD0765  [3]
 LDCM0449  CL58 HCT 116 C445(1.00)  LDD0766  [3]
 LDCM0450  CL59 HCT 116 C445(1.24)  LDD0767  [3]
 LDCM0451  CL6 HCT 116 C445(0.92)  LDD0768  [3]
 LDCM0452  CL60 HCT 116 C445(1.07)  LDD0769  [3]
 LDCM0453  CL61 HEK-293T C353(0.97)  LDD1656  [8]
 LDCM0454  CL62 HEK-293T C353(0.94)  LDD1657  [8]
 LDCM0455  CL63 HEK-293T C353(1.08)  LDD1658  [8]
 LDCM0456  CL64 HEK-293T C353(1.10)  LDD1659  [8]
 LDCM0457  CL65 HEK-293T C353(1.01)  LDD1660  [8]
 LDCM0458  CL66 HEK-293T C353(0.94)  LDD1661  [8]
 LDCM0459  CL67 HEK-293T C353(1.08)  LDD1662  [8]
 LDCM0460  CL68 HEK-293T C353(1.08)  LDD1663  [8]
 LDCM0461  CL69 HEK-293T C353(0.94)  LDD1664  [8]
 LDCM0462  CL7 HCT 116 C445(0.77)  LDD0779  [3]
 LDCM0463  CL70 HEK-293T C353(0.96); C445(1.23)  LDD1666  [8]
 LDCM0464  CL71 HEK-293T C353(1.03)  LDD1667  [8]
 LDCM0465  CL72 HEK-293T C353(1.03); C445(1.07)  LDD1668  [8]
 LDCM0466  CL73 HEK-293T C353(0.96)  LDD1669  [8]
 LDCM0467  CL74 HEK-293T C353(1.06)  LDD1670  [8]
 LDCM0469  CL76 HEK-293T C353(0.99)  LDD1672  [8]
 LDCM0470  CL77 HEK-293T C353(1.00)  LDD1673  [8]
 LDCM0471  CL78 HEK-293T C353(0.93)  LDD1674  [8]
 LDCM0472  CL79 HEK-293T C353(1.00)  LDD1675  [8]
 LDCM0473  CL8 HCT 116 C445(0.81)  LDD0790  [3]
 LDCM0474  CL80 HEK-293T C353(1.08)  LDD1677  [8]
 LDCM0475  CL81 HEK-293T C353(1.03)  LDD1678  [8]
 LDCM0476  CL82 HEK-293T C353(0.94); C445(1.05)  LDD1679  [8]
 LDCM0477  CL83 HEK-293T C353(1.04)  LDD1680  [8]
 LDCM0478  CL84 HEK-293T C353(0.97); C445(1.00)  LDD1681  [8]
 LDCM0479  CL85 HEK-293T C353(0.96)  LDD1682  [8]
 LDCM0480  CL86 HEK-293T C353(0.89)  LDD1683  [8]
 LDCM0481  CL87 HEK-293T C353(1.02)  LDD1684  [8]
 LDCM0482  CL88 HEK-293T C353(1.17)  LDD1685  [8]
 LDCM0483  CL89 HEK-293T C353(0.98)  LDD1686  [8]
 LDCM0484  CL9 HCT 116 C445(0.66)  LDD0801  [3]
 LDCM0485  CL90 HEK-293T C353(0.78)  LDD1688  [8]
 LDCM0486  CL91 HCT 116 C445(0.95)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C445(0.81)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C445(0.94)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C445(1.03)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C445(0.91)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C445(1.07)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C445(1.01)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C445(0.88)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C445(0.98)  LDD0811  [3]
 LDCM0495  E2913 HEK-293T C353(1.16)  LDD1698  [8]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C353(2.24)  LDD1702  [9]
 LDCM0468  Fragment33 HEK-293T C353(1.03)  LDD1671  [8]
 LDCM0427  Fragment51 HEK-293T C353(0.94)  LDD1631  [8]
 LDCM0022  KB02 HEK-293T C642(0.88)  LDD1492  [8]
 LDCM0023  KB03 HEK-293T C642(1.05)  LDD1497  [8]
 LDCM0024  KB05 HMCB C353(1.98)  LDD3312  [10]
 LDCM0112  W16 Hep-G2 C353(0.71)  LDD0239  [7]

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
5 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
6 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
7 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
8 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
9 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
10 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840