Details of the Target

General Information of Target

Target ID LDTP19557
Target Name Leucine-rich repeat-containing protein 74B (LRRC74B)
Gene Name LRRC74B
Gene ID 400891
Synonyms
Leucine-rich repeat-containing protein 74B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MRNMIPQDNENPPQQGEANQNDSVAFEDVAVNFTPDEWALLDPSQKNLYREVMQETLRNL
ASIEVLWKRDSLKVKVISMEKF
Target Bioclass
Other
Uniprot ID
Q6ZQY2
Ensemble ID
ENST00000442047.3
HGNC ID
HGNC:34301

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AN3CA SNV: p.S104N .
DU145 SNV: p.L91P .
Ishikawa (Heraklio) 02 ER SNV: p.L61P .
LS180 SNV: p.E278D .
MFE319 SNV: p.L43P .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
W1
 Probe Info  		H88(2.14)  LDD0239  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0112  W16 Hep-G2 H88(2.14)  LDD0239  [1]

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.