Details of the Target

General Information of Target

Target ID LDTP19969
Target Name Proline-rich protein 36 (PRR36)
Gene Name PRR36
Gene ID 80164
Synonyms
Proline-rich protein 36
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MHNPDGSASPTADPGSELQTLGQAARRPPPPRAGHDAPRRTRPSARKPLSCFSRRPMPTR
EPPKTRGSRGHLHTHPPGPGPPLQGLAPRGLKTSAPRPPCQPQPGPHKAKTKKIVFEDEL
LSQALLGAKKPIGAIPKGHKPRPHPVPDYELKYPPVSSERERSRYVAVFQDQYGEFLELQ
HEVGCAQAKLRQLEALLSSLPPPQSQKEAQVAARVWREFEMKRMDPGFLDKQARCHYLKG
KLRHLKTQIQKFDDQGDSEGSVYF
Target Bioclass
Other
Uniprot ID
Q9H6K5
Ensemble ID
ENST00000618550.5
HGNC ID
HGNC:26172

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CAL72 Substitution: p.P519F .
HCT116 Deletion: p.L833CfsTer89 .
HCT15 SNV: p.A344V; p.P603H .
HUPT3 SNV: p.A373V .
IGROV1 Deletion: p.L833CfsTer89 .
IM95 Deletion: p.P674CfsTer331
SNV: p.P269H		 .
KELLY SNV: p.A1058E .
KMCH1 SNV: p.S704C .
KMS27 SNV: p.P505L .
KYSE180 SNV: p.P377S .
KYSE410 SNV: p.P925S .
MCC13 SNV: p.T109I .
OVK18 SNV: p.Q842H .
RKO Deletion: p.T437PfsTer56
SNV: p.A13T;p.A934T		 .
RL952 SNV: p.S360L .
SNU1 Deletion: p.G64AfsTer146 .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
W1
 Probe Info  		D1299(2.08)  LDD0239  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0112  W16 Hep-G2 D1299(2.08)  LDD0239  [1]

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.