Details of the Target
General Information of Target
Target ID | LDTP09690 | |||||
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Target Name | Gem-associated protein 6 (GEMIN6) | |||||
Gene Name | GEMIN6 | |||||
Gene ID | 79833 | |||||
Synonyms |
Gem-associated protein 6; Gemin-6; SIP2 |
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3D Structure | ||||||
Sequence |
MSEWMKKGPLEWQDYIYKEVRVTASEKNEYKGWVLTTDPVSANIVLVNFLEDGSMSVTGI
MGHAVQTVETMNEGDHRVREKLMHLFTSGDCKAYSPEDLEERKNSLKKWLEKNHIPITEQ GDAPRTLCVAGVLTIDPPYGPENCSSSNEIILSRVQDLIEGHLTASQ |
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Target Bioclass |
Other
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Subcellular location |
Nucleus, nucleoplasm
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Function |
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP.
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Uniprot ID | ||||||
Ensemble ID | ||||||
HGNC ID |
Probe(s) Labeling This Target
ABPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
---|---|---|---|---|---|
m-APA Probe Info |
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14.19 | LDD0403 | [1] | |
AHL-Pu-1 Probe Info |
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C91(2.39) | LDD0169 | [2] | |
HHS-465 Probe Info |
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Y94(5.53) | LDD2237 | [3] | |
DBIA Probe Info |
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C91(1.06) | LDD0078 | [4] | |
5E-2FA Probe Info |
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N.A. | LDD2235 | [5] | |
ATP probe Probe Info |
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N.A. | LDD0199 | [6] | |
4-Iodoacetamidophenylacetylene Probe Info |
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N.A. | LDD0038 | [7] | |
IA-alkyne Probe Info |
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N.A. | LDD0036 | [7] | |
Lodoacetamide azide Probe Info |
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N.A. | LDD0037 | [7] | |
NAIA_4 Probe Info |
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N.A. | LDD2226 | [8] | |
NAIA_5 Probe Info |
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N.A. | LDD2224 | [8] | |
Compound 10 Probe Info |
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N.A. | LDD2216 | [9] | |
IPM Probe Info |
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N.A. | LDD0005 | [10] | |
Phosphinate-6 Probe Info |
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N.A. | LDD0018 | [11] | |
Acrolein Probe Info |
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N.A. | LDD0217 | [12] | |
W1 Probe Info |
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N.A. | LDD0236 | [13] | |
AOyne Probe Info |
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15.00 | LDD0443 | [14] |
Competitor(s) Related to This Target
Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
---|---|---|---|---|---|
LDCM0026 | 4SU-RNA+native RNA | HEK-293T | C91(2.39) | LDD0169 | [2] |
LDCM0214 | AC1 | HCT 116 | C91(1.10) | LDD0531 | [4] |
LDCM0215 | AC10 | HCT 116 | C91(1.08) | LDD0532 | [4] |
LDCM0216 | AC100 | HCT 116 | C91(0.83) | LDD0533 | [4] |
LDCM0217 | AC101 | HCT 116 | C91(0.99) | LDD0534 | [4] |
LDCM0218 | AC102 | HCT 116 | C91(0.98) | LDD0535 | [4] |
LDCM0219 | AC103 | HCT 116 | C91(1.07) | LDD0536 | [4] |
LDCM0220 | AC104 | HCT 116 | C91(1.02) | LDD0537 | [4] |
LDCM0221 | AC105 | HCT 116 | C91(0.95) | LDD0538 | [4] |
LDCM0222 | AC106 | HCT 116 | C91(1.05) | LDD0539 | [4] |
LDCM0223 | AC107 | HCT 116 | C91(0.93) | LDD0540 | [4] |
LDCM0224 | AC108 | HCT 116 | C91(0.90) | LDD0541 | [4] |
LDCM0225 | AC109 | HCT 116 | C91(0.93) | LDD0542 | [4] |
LDCM0226 | AC11 | HCT 116 | C91(1.12) | LDD0543 | [4] |
LDCM0227 | AC110 | HCT 116 | C91(1.02) | LDD0544 | [4] |
LDCM0228 | AC111 | HCT 116 | C91(1.13) | LDD0545 | [4] |
LDCM0229 | AC112 | HCT 116 | C91(1.13) | LDD0546 | [4] |
LDCM0230 | AC113 | HCT 116 | C91(0.99) | LDD0547 | [4] |
LDCM0231 | AC114 | HCT 116 | C91(0.90) | LDD0548 | [4] |
LDCM0232 | AC115 | HCT 116 | C91(1.02) | LDD0549 | [4] |
LDCM0233 | AC116 | HCT 116 | C91(0.95) | LDD0550 | [4] |
LDCM0234 | AC117 | HCT 116 | C91(1.36) | LDD0551 | [4] |
LDCM0235 | AC118 | HCT 116 | C91(1.07) | LDD0552 | [4] |
LDCM0236 | AC119 | HCT 116 | C91(1.21) | LDD0553 | [4] |
LDCM0237 | AC12 | HCT 116 | C91(1.11) | LDD0554 | [4] |
LDCM0238 | AC120 | HCT 116 | C91(0.97) | LDD0555 | [4] |
LDCM0239 | AC121 | HCT 116 | C91(1.51) | LDD0556 | [4] |
LDCM0240 | AC122 | HCT 116 | C91(0.91) | LDD0557 | [4] |
LDCM0241 | AC123 | HCT 116 | C91(1.24) | LDD0558 | [4] |
LDCM0242 | AC124 | HCT 116 | C91(1.23) | LDD0559 | [4] |
LDCM0243 | AC125 | HCT 116 | C91(0.88) | LDD0560 | [4] |
LDCM0244 | AC126 | HCT 116 | C91(0.81) | LDD0561 | [4] |
LDCM0245 | AC127 | HCT 116 | C91(1.16) | LDD0562 | [4] |
LDCM0246 | AC128 | HCT 116 | C91(1.09) | LDD0563 | [4] |
LDCM0247 | AC129 | HCT 116 | C91(0.87) | LDD0564 | [4] |
LDCM0249 | AC130 | HCT 116 | C91(0.96) | LDD0566 | [4] |
LDCM0250 | AC131 | HCT 116 | C91(0.95) | LDD0567 | [4] |
LDCM0251 | AC132 | HCT 116 | C91(0.90) | LDD0568 | [4] |
LDCM0252 | AC133 | HCT 116 | C91(1.06) | LDD0569 | [4] |
LDCM0253 | AC134 | HCT 116 | C91(1.21) | LDD0570 | [4] |
LDCM0254 | AC135 | HCT 116 | C91(1.06) | LDD0571 | [4] |
LDCM0255 | AC136 | HCT 116 | C91(1.07) | LDD0572 | [4] |
LDCM0256 | AC137 | HCT 116 | C91(1.04) | LDD0573 | [4] |
LDCM0257 | AC138 | HCT 116 | C91(1.00) | LDD0574 | [4] |
LDCM0258 | AC139 | HCT 116 | C91(1.07) | LDD0575 | [4] |
LDCM0259 | AC14 | HCT 116 | C91(1.09) | LDD0576 | [4] |
LDCM0260 | AC140 | HCT 116 | C91(1.04) | LDD0577 | [4] |
LDCM0261 | AC141 | HCT 116 | C91(0.98) | LDD0578 | [4] |
LDCM0262 | AC142 | HCT 116 | C91(0.89) | LDD0579 | [4] |
LDCM0263 | AC143 | HCT 116 | C91(1.07) | LDD0580 | [4] |
LDCM0264 | AC144 | HCT 116 | C91(1.30) | LDD0581 | [4] |
LDCM0265 | AC145 | HCT 116 | C91(1.19) | LDD0582 | [4] |
LDCM0266 | AC146 | HCT 116 | C91(1.36) | LDD0583 | [4] |
LDCM0267 | AC147 | HCT 116 | C91(1.34) | LDD0584 | [4] |
LDCM0268 | AC148 | HCT 116 | C91(1.70) | LDD0585 | [4] |
LDCM0269 | AC149 | HCT 116 | C91(1.44) | LDD0586 | [4] |
LDCM0270 | AC15 | HCT 116 | C91(1.08) | LDD0587 | [4] |
LDCM0271 | AC150 | HCT 116 | C91(1.17) | LDD0588 | [4] |
LDCM0272 | AC151 | HCT 116 | C91(1.12) | LDD0589 | [4] |
LDCM0273 | AC152 | HCT 116 | C91(1.40) | LDD0590 | [4] |
LDCM0274 | AC153 | HCT 116 | C91(1.78) | LDD0591 | [4] |
LDCM0621 | AC154 | HCT 116 | C91(1.30) | LDD2158 | [4] |
LDCM0622 | AC155 | HCT 116 | C91(1.19) | LDD2159 | [4] |
LDCM0623 | AC156 | HCT 116 | C91(1.03) | LDD2160 | [4] |
LDCM0624 | AC157 | HCT 116 | C91(1.01) | LDD2161 | [4] |
LDCM0276 | AC17 | HCT 116 | C91(1.19) | LDD0593 | [4] |
LDCM0277 | AC18 | HCT 116 | C91(1.59) | LDD0594 | [4] |
LDCM0278 | AC19 | HCT 116 | C91(1.17) | LDD0595 | [4] |
LDCM0279 | AC2 | HCT 116 | C91(1.02) | LDD0596 | [4] |
LDCM0280 | AC20 | HCT 116 | C91(1.21) | LDD0597 | [4] |
LDCM0281 | AC21 | HCT 116 | C91(1.21) | LDD0598 | [4] |
LDCM0282 | AC22 | HCT 116 | C91(1.14) | LDD0599 | [4] |
LDCM0283 | AC23 | HCT 116 | C91(1.23) | LDD0600 | [4] |
LDCM0284 | AC24 | HCT 116 | C91(1.13) | LDD0601 | [4] |
LDCM0285 | AC25 | HCT 116 | C91(0.98) | LDD0602 | [4] |
LDCM0286 | AC26 | HCT 116 | C91(1.11) | LDD0603 | [4] |
LDCM0287 | AC27 | HCT 116 | C91(1.10) | LDD0604 | [4] |
LDCM0288 | AC28 | HCT 116 | C91(1.08) | LDD0605 | [4] |
LDCM0289 | AC29 | HCT 116 | C91(1.09) | LDD0606 | [4] |
LDCM0290 | AC3 | HCT 116 | C91(0.95) | LDD0607 | [4] |
LDCM0291 | AC30 | HCT 116 | C91(1.28) | LDD0608 | [4] |
LDCM0292 | AC31 | HCT 116 | C91(1.12) | LDD0609 | [4] |
LDCM0293 | AC32 | HCT 116 | C91(1.35) | LDD0610 | [4] |
LDCM0294 | AC33 | HCT 116 | C91(1.26) | LDD0611 | [4] |
LDCM0295 | AC34 | HCT 116 | C91(1.38) | LDD0612 | [4] |
LDCM0296 | AC35 | HCT 116 | C91(0.91) | LDD0613 | [4] |
LDCM0297 | AC36 | HCT 116 | C91(0.89) | LDD0614 | [4] |
LDCM0298 | AC37 | HCT 116 | C91(0.91) | LDD0615 | [4] |
LDCM0299 | AC38 | HCT 116 | C91(0.91) | LDD0616 | [4] |
LDCM0300 | AC39 | HCT 116 | C91(0.96) | LDD0617 | [4] |
LDCM0301 | AC4 | HCT 116 | C91(1.10) | LDD0618 | [4] |
LDCM0302 | AC40 | HCT 116 | C91(1.08) | LDD0619 | [4] |
LDCM0303 | AC41 | HCT 116 | C91(1.00) | LDD0620 | [4] |
LDCM0304 | AC42 | HCT 116 | C91(1.06) | LDD0621 | [4] |
LDCM0305 | AC43 | HCT 116 | C91(1.06) | LDD0622 | [4] |
LDCM0306 | AC44 | HCT 116 | C91(1.02) | LDD0623 | [4] |
LDCM0307 | AC45 | HCT 116 | C91(1.14) | LDD0624 | [4] |
LDCM0308 | AC46 | HCT 116 | C91(1.04) | LDD0625 | [4] |
LDCM0309 | AC47 | HCT 116 | C91(0.94) | LDD0626 | [4] |
LDCM0310 | AC48 | HCT 116 | C91(0.96) | LDD0627 | [4] |
LDCM0311 | AC49 | HCT 116 | C91(1.45) | LDD0628 | [4] |
LDCM0312 | AC5 | HCT 116 | C91(1.11) | LDD0629 | [4] |
LDCM0313 | AC50 | HCT 116 | C91(1.28) | LDD0630 | [4] |
LDCM0314 | AC51 | HCT 116 | C91(0.94) | LDD0631 | [4] |
LDCM0315 | AC52 | HCT 116 | C91(1.03) | LDD0632 | [4] |
LDCM0316 | AC53 | HCT 116 | C91(1.10) | LDD0633 | [4] |
LDCM0317 | AC54 | HCT 116 | C91(1.16) | LDD0634 | [4] |
LDCM0318 | AC55 | HCT 116 | C91(1.22) | LDD0635 | [4] |
LDCM0319 | AC56 | HCT 116 | C91(1.58) | LDD0636 | [4] |
LDCM0320 | AC57 | HCT 116 | C91(1.33) | LDD0637 | [4] |
LDCM0321 | AC58 | HCT 116 | C91(1.33) | LDD0638 | [4] |
LDCM0322 | AC59 | HCT 116 | C91(1.27) | LDD0639 | [4] |
LDCM0323 | AC6 | HCT 116 | C91(1.23) | LDD0640 | [4] |
LDCM0324 | AC60 | HCT 116 | C91(1.21) | LDD0641 | [4] |
LDCM0325 | AC61 | HCT 116 | C91(1.24) | LDD0642 | [4] |
LDCM0326 | AC62 | HCT 116 | C91(1.39) | LDD0643 | [4] |
LDCM0327 | AC63 | HCT 116 | C91(1.24) | LDD0644 | [4] |
LDCM0328 | AC64 | HCT 116 | C91(1.40) | LDD0645 | [4] |
LDCM0329 | AC65 | HCT 116 | C91(1.43) | LDD0646 | [4] |
LDCM0330 | AC66 | HCT 116 | C91(1.38) | LDD0647 | [4] |
LDCM0331 | AC67 | HCT 116 | C91(1.51) | LDD0648 | [4] |
LDCM0332 | AC68 | HCT 116 | C91(1.02) | LDD0649 | [4] |
LDCM0333 | AC69 | HCT 116 | C91(0.98) | LDD0650 | [4] |
LDCM0334 | AC7 | HCT 116 | C91(1.12) | LDD0651 | [4] |
LDCM0335 | AC70 | HCT 116 | C91(0.94) | LDD0652 | [4] |
LDCM0336 | AC71 | HCT 116 | C91(0.87) | LDD0653 | [4] |
LDCM0337 | AC72 | HCT 116 | C91(0.96) | LDD0654 | [4] |
LDCM0338 | AC73 | HCT 116 | C91(0.96) | LDD0655 | [4] |
LDCM0339 | AC74 | HCT 116 | C91(0.93) | LDD0656 | [4] |
LDCM0340 | AC75 | HCT 116 | C91(0.97) | LDD0657 | [4] |
LDCM0341 | AC76 | HCT 116 | C91(0.88) | LDD0658 | [4] |
LDCM0342 | AC77 | HCT 116 | C91(1.05) | LDD0659 | [4] |
LDCM0343 | AC78 | HCT 116 | C91(0.93) | LDD0660 | [4] |
LDCM0344 | AC79 | HCT 116 | C91(1.01) | LDD0661 | [4] |
LDCM0345 | AC8 | HCT 116 | C91(1.02) | LDD0662 | [4] |
LDCM0346 | AC80 | HCT 116 | C91(0.85) | LDD0663 | [4] |
LDCM0347 | AC81 | HCT 116 | C91(0.94) | LDD0664 | [4] |
LDCM0348 | AC82 | HCT 116 | C91(0.90) | LDD0665 | [4] |
LDCM0349 | AC83 | HCT 116 | C91(1.30) | LDD0666 | [4] |
LDCM0350 | AC84 | HCT 116 | C91(1.24) | LDD0667 | [4] |
LDCM0351 | AC85 | HCT 116 | C91(1.09) | LDD0668 | [4] |
LDCM0352 | AC86 | HCT 116 | C91(1.13) | LDD0669 | [4] |
LDCM0353 | AC87 | HCT 116 | C91(0.96) | LDD0670 | [4] |
LDCM0354 | AC88 | HCT 116 | C91(1.01) | LDD0671 | [4] |
LDCM0355 | AC89 | HCT 116 | C91(1.05) | LDD0672 | [4] |
LDCM0357 | AC90 | HCT 116 | C91(0.91) | LDD0674 | [4] |
LDCM0358 | AC91 | HCT 116 | C91(1.23) | LDD0675 | [4] |
LDCM0359 | AC92 | HCT 116 | C91(1.23) | LDD0676 | [4] |
LDCM0360 | AC93 | HCT 116 | C91(1.10) | LDD0677 | [4] |
LDCM0361 | AC94 | HCT 116 | C91(1.09) | LDD0678 | [4] |
LDCM0362 | AC95 | HCT 116 | C91(1.06) | LDD0679 | [4] |
LDCM0363 | AC96 | HCT 116 | C91(1.18) | LDD0680 | [4] |
LDCM0364 | AC97 | HCT 116 | C91(1.23) | LDD0681 | [4] |
LDCM0365 | AC98 | HCT 116 | C91(1.13) | LDD0682 | [4] |
LDCM0366 | AC99 | HCT 116 | C91(0.96) | LDD0683 | [4] |
LDCM0248 | AKOS034007472 | HCT 116 | C91(1.07) | LDD0565 | [4] |
LDCM0356 | AKOS034007680 | HCT 116 | C91(1.10) | LDD0673 | [4] |
LDCM0275 | AKOS034007705 | HCT 116 | C91(1.19) | LDD0592 | [4] |
LDCM0156 | Aniline | NCI-H1299 | 14.19 | LDD0403 | [1] |
LDCM0020 | ARS-1620 | HCC44 | C91(1.06) | LDD0078 | [4] |
LDCM0108 | Chloroacetamide | HeLa | N.A. | LDD0222 | [12] |
LDCM0632 | CL-Sc | Hep-G2 | C91(3.15); C91(1.33) | LDD2227 | [8] |
LDCM0367 | CL1 | HCT 116 | C91(1.13) | LDD0684 | [4] |
LDCM0368 | CL10 | HCT 116 | C91(1.49) | LDD0685 | [4] |
LDCM0369 | CL100 | HCT 116 | C91(1.10) | LDD0686 | [4] |
LDCM0370 | CL101 | HCT 116 | C91(1.10) | LDD0687 | [4] |
LDCM0371 | CL102 | HCT 116 | C91(1.24) | LDD0688 | [4] |
LDCM0372 | CL103 | HCT 116 | C91(1.05) | LDD0689 | [4] |
LDCM0373 | CL104 | HCT 116 | C91(1.18) | LDD0690 | [4] |
LDCM0374 | CL105 | HCT 116 | C91(1.33) | LDD0691 | [4] |
LDCM0375 | CL106 | HCT 116 | C91(1.70) | LDD0692 | [4] |
LDCM0376 | CL107 | HCT 116 | C91(1.51) | LDD0693 | [4] |
LDCM0377 | CL108 | HCT 116 | C91(1.59) | LDD0694 | [4] |
LDCM0378 | CL109 | HCT 116 | C91(1.37) | LDD0695 | [4] |
LDCM0379 | CL11 | HCT 116 | C91(1.46) | LDD0696 | [4] |
LDCM0380 | CL110 | HCT 116 | C91(1.35) | LDD0697 | [4] |
LDCM0381 | CL111 | HCT 116 | C91(1.37) | LDD0698 | [4] |
LDCM0382 | CL112 | HCT 116 | C91(1.07) | LDD0699 | [4] |
LDCM0383 | CL113 | HCT 116 | C91(1.35) | LDD0700 | [4] |
LDCM0384 | CL114 | HCT 116 | C91(1.33) | LDD0701 | [4] |
LDCM0385 | CL115 | HCT 116 | C91(1.22) | LDD0702 | [4] |
LDCM0386 | CL116 | HCT 116 | C91(1.18) | LDD0703 | [4] |
LDCM0387 | CL117 | HCT 116 | C91(1.26) | LDD0704 | [4] |
LDCM0388 | CL118 | HCT 116 | C91(1.00) | LDD0705 | [4] |
LDCM0389 | CL119 | HCT 116 | C91(1.11) | LDD0706 | [4] |
LDCM0390 | CL12 | HCT 116 | C91(1.25) | LDD0707 | [4] |
LDCM0391 | CL120 | HCT 116 | C91(0.94) | LDD0708 | [4] |
LDCM0392 | CL121 | HCT 116 | C91(1.09) | LDD0709 | [4] |
LDCM0393 | CL122 | HCT 116 | C91(1.20) | LDD0710 | [4] |
LDCM0394 | CL123 | HCT 116 | C91(1.32) | LDD0711 | [4] |
LDCM0395 | CL124 | HCT 116 | C91(1.29) | LDD0712 | [4] |
LDCM0396 | CL125 | HCT 116 | C91(1.02) | LDD0713 | [4] |
LDCM0397 | CL126 | HCT 116 | C91(1.13) | LDD0714 | [4] |
LDCM0398 | CL127 | HCT 116 | C91(1.15) | LDD0715 | [4] |
LDCM0399 | CL128 | HCT 116 | C91(1.14) | LDD0716 | [4] |
LDCM0400 | CL13 | HCT 116 | C91(1.27) | LDD0717 | [4] |
LDCM0401 | CL14 | HCT 116 | C91(1.26) | LDD0718 | [4] |
LDCM0402 | CL15 | HCT 116 | C91(1.34) | LDD0719 | [4] |
LDCM0403 | CL16 | HCT 116 | C91(1.03) | LDD0720 | [4] |
LDCM0404 | CL17 | HCT 116 | C91(1.00) | LDD0721 | [4] |
LDCM0405 | CL18 | HCT 116 | C91(1.13) | LDD0722 | [4] |
LDCM0406 | CL19 | HCT 116 | C91(1.08) | LDD0723 | [4] |
LDCM0407 | CL2 | HCT 116 | C91(1.08) | LDD0724 | [4] |
LDCM0408 | CL20 | HCT 116 | C91(1.14) | LDD0725 | [4] |
LDCM0409 | CL21 | HCT 116 | C91(1.31) | LDD0726 | [4] |
LDCM0410 | CL22 | HCT 116 | C91(1.43) | LDD0727 | [4] |
LDCM0411 | CL23 | HCT 116 | C91(1.12) | LDD0728 | [4] |
LDCM0412 | CL24 | HCT 116 | C91(1.11) | LDD0729 | [4] |
LDCM0413 | CL25 | HCT 116 | C91(1.23) | LDD0730 | [4] |
LDCM0414 | CL26 | HCT 116 | C91(1.00) | LDD0731 | [4] |
LDCM0415 | CL27 | HCT 116 | C91(0.99) | LDD0732 | [4] |
LDCM0416 | CL28 | HCT 116 | C91(1.12) | LDD0733 | [4] |
LDCM0417 | CL29 | HCT 116 | C91(1.17) | LDD0734 | [4] |
LDCM0418 | CL3 | HCT 116 | C91(1.01) | LDD0735 | [4] |
LDCM0419 | CL30 | HCT 116 | C91(1.04) | LDD0736 | [4] |
LDCM0420 | CL31 | HCT 116 | C91(1.04) | LDD0737 | [4] |
LDCM0421 | CL32 | HCT 116 | C91(1.04) | LDD0738 | [4] |
LDCM0422 | CL33 | HCT 116 | C91(1.05) | LDD0739 | [4] |
LDCM0423 | CL34 | HCT 116 | C91(1.16) | LDD0740 | [4] |
LDCM0424 | CL35 | HCT 116 | C91(1.07) | LDD0741 | [4] |
LDCM0425 | CL36 | HCT 116 | C91(1.20) | LDD0742 | [4] |
LDCM0426 | CL37 | HCT 116 | C91(1.16) | LDD0743 | [4] |
LDCM0428 | CL39 | HCT 116 | C91(0.94) | LDD0745 | [4] |
LDCM0429 | CL4 | HCT 116 | C91(1.13) | LDD0746 | [4] |
LDCM0430 | CL40 | HCT 116 | C91(1.12) | LDD0747 | [4] |
LDCM0431 | CL41 | HCT 116 | C91(1.03) | LDD0748 | [4] |
LDCM0432 | CL42 | HCT 116 | C91(1.07) | LDD0749 | [4] |
LDCM0433 | CL43 | HCT 116 | C91(0.97) | LDD0750 | [4] |
LDCM0434 | CL44 | HCT 116 | C91(1.07) | LDD0751 | [4] |
LDCM0435 | CL45 | HCT 116 | C91(1.08) | LDD0752 | [4] |
LDCM0436 | CL46 | HCT 116 | C91(0.88) | LDD0753 | [4] |
LDCM0437 | CL47 | HCT 116 | C91(0.87) | LDD0754 | [4] |
LDCM0438 | CL48 | HCT 116 | C91(0.91) | LDD0755 | [4] |
LDCM0439 | CL49 | HCT 116 | C91(0.88) | LDD0756 | [4] |
LDCM0440 | CL5 | HCT 116 | C91(1.02) | LDD0757 | [4] |
LDCM0441 | CL50 | HCT 116 | C91(0.90) | LDD0758 | [4] |
LDCM0442 | CL51 | HCT 116 | C91(0.91) | LDD0759 | [4] |
LDCM0443 | CL52 | HCT 116 | C91(0.95) | LDD0760 | [4] |
LDCM0444 | CL53 | HCT 116 | C91(1.03) | LDD0761 | [4] |
LDCM0445 | CL54 | HCT 116 | C91(0.88) | LDD0762 | [4] |
LDCM0446 | CL55 | HCT 116 | C91(0.89) | LDD0763 | [4] |
LDCM0447 | CL56 | HCT 116 | C91(0.96) | LDD0764 | [4] |
LDCM0448 | CL57 | HCT 116 | C91(0.95) | LDD0765 | [4] |
LDCM0449 | CL58 | HCT 116 | C91(0.91) | LDD0766 | [4] |
LDCM0450 | CL59 | HCT 116 | C91(0.89) | LDD0767 | [4] |
LDCM0451 | CL6 | HCT 116 | C91(1.08) | LDD0768 | [4] |
LDCM0452 | CL60 | HCT 116 | C91(0.95) | LDD0769 | [4] |
LDCM0453 | CL61 | HCT 116 | C91(1.05) | LDD0770 | [4] |
LDCM0454 | CL62 | HCT 116 | C91(1.03) | LDD0771 | [4] |
LDCM0455 | CL63 | HCT 116 | C91(1.14) | LDD0772 | [4] |
LDCM0456 | CL64 | HCT 116 | C91(1.30) | LDD0773 | [4] |
LDCM0457 | CL65 | HCT 116 | C91(1.08) | LDD0774 | [4] |
LDCM0458 | CL66 | HCT 116 | C91(1.38) | LDD0775 | [4] |
LDCM0459 | CL67 | HCT 116 | C91(1.30) | LDD0776 | [4] |
LDCM0460 | CL68 | HCT 116 | C91(1.34) | LDD0777 | [4] |
LDCM0461 | CL69 | HCT 116 | C91(1.21) | LDD0778 | [4] |
LDCM0462 | CL7 | HCT 116 | C91(1.21) | LDD0779 | [4] |
LDCM0463 | CL70 | HCT 116 | C91(1.16) | LDD0780 | [4] |
LDCM0464 | CL71 | HCT 116 | C91(1.26) | LDD0781 | [4] |
LDCM0465 | CL72 | HCT 116 | C91(1.14) | LDD0782 | [4] |
LDCM0466 | CL73 | HCT 116 | C91(1.43) | LDD0783 | [4] |
LDCM0467 | CL74 | HCT 116 | C91(1.24) | LDD0784 | [4] |
LDCM0469 | CL76 | HCT 116 | C91(1.14) | LDD0786 | [4] |
LDCM0470 | CL77 | HCT 116 | C91(1.27) | LDD0787 | [4] |
LDCM0471 | CL78 | HCT 116 | C91(1.11) | LDD0788 | [4] |
LDCM0472 | CL79 | HCT 116 | C91(1.18) | LDD0789 | [4] |
LDCM0473 | CL8 | HCT 116 | C91(1.74) | LDD0790 | [4] |
LDCM0474 | CL80 | HCT 116 | C91(0.93) | LDD0791 | [4] |
LDCM0475 | CL81 | HCT 116 | C91(1.02) | LDD0792 | [4] |
LDCM0476 | CL82 | HCT 116 | C91(1.01) | LDD0793 | [4] |
LDCM0477 | CL83 | HCT 116 | C91(1.17) | LDD0794 | [4] |
LDCM0478 | CL84 | HCT 116 | C91(1.02) | LDD0795 | [4] |
LDCM0479 | CL85 | HCT 116 | C91(1.11) | LDD0796 | [4] |
LDCM0480 | CL86 | HCT 116 | C91(1.00) | LDD0797 | [4] |
LDCM0481 | CL87 | HCT 116 | C91(1.03) | LDD0798 | [4] |
LDCM0482 | CL88 | HCT 116 | C91(1.16) | LDD0799 | [4] |
LDCM0483 | CL89 | HCT 116 | C91(0.98) | LDD0800 | [4] |
LDCM0484 | CL9 | HCT 116 | C91(1.21) | LDD0801 | [4] |
LDCM0485 | CL90 | HCT 116 | C91(1.59) | LDD0802 | [4] |
LDCM0486 | CL91 | HCT 116 | C91(1.03) | LDD0803 | [4] |
LDCM0487 | CL92 | HCT 116 | C91(1.15) | LDD0804 | [4] |
LDCM0488 | CL93 | HCT 116 | C91(0.97) | LDD0805 | [4] |
LDCM0489 | CL94 | HCT 116 | C91(1.29) | LDD0806 | [4] |
LDCM0490 | CL95 | HCT 116 | C91(1.32) | LDD0807 | [4] |
LDCM0491 | CL96 | HCT 116 | C91(1.10) | LDD0808 | [4] |
LDCM0492 | CL97 | HCT 116 | C91(1.10) | LDD0809 | [4] |
LDCM0493 | CL98 | HCT 116 | C91(1.09) | LDD0810 | [4] |
LDCM0494 | CL99 | HCT 116 | C91(1.10) | LDD0811 | [4] |
LDCM0634 | CY-0357 | Hep-G2 | C91(0.32) | LDD2228 | [8] |
LDCM0495 | E2913 | HEK-293T | C91(0.96); C128(1.08) | LDD1698 | [15] |
LDCM0213 | Electrophilic fragment 2 | MDA-MB-231 | C91(3.37) | LDD1702 | [16] |
LDCM0625 | F8 | Ramos | C91(1.27) | LDD2187 | [17] |
LDCM0572 | Fragment10 | Ramos | C91(1.60) | LDD2189 | [17] |
LDCM0573 | Fragment11 | Ramos | C91(1.29) | LDD2190 | [17] |
LDCM0574 | Fragment12 | Ramos | C91(2.08) | LDD2191 | [17] |
LDCM0575 | Fragment13 | Ramos | C91(1.52) | LDD2192 | [17] |
LDCM0576 | Fragment14 | Ramos | C91(1.21) | LDD2193 | [17] |
LDCM0579 | Fragment20 | Ramos | C91(2.51) | LDD2194 | [17] |
LDCM0580 | Fragment21 | Ramos | C91(0.97) | LDD2195 | [17] |
LDCM0582 | Fragment23 | Ramos | C91(0.86) | LDD2196 | [17] |
LDCM0578 | Fragment27 | Ramos | C91(1.25) | LDD2197 | [17] |
LDCM0586 | Fragment28 | Ramos | C91(1.65) | LDD2198 | [17] |
LDCM0588 | Fragment30 | Ramos | C91(1.06) | LDD2199 | [17] |
LDCM0589 | Fragment31 | Ramos | C91(0.94) | LDD2200 | [17] |
LDCM0590 | Fragment32 | Ramos | C91(1.77) | LDD2201 | [17] |
LDCM0468 | Fragment33 | HCT 116 | C91(1.21) | LDD0785 | [4] |
LDCM0596 | Fragment38 | Ramos | C91(1.64) | LDD2203 | [17] |
LDCM0566 | Fragment4 | Ramos | C91(1.19) | LDD2184 | [17] |
LDCM0427 | Fragment51 | HCT 116 | C91(1.29) | LDD0744 | [4] |
LDCM0610 | Fragment52 | Ramos | C91(1.12) | LDD2204 | [17] |
LDCM0614 | Fragment56 | Ramos | C91(1.24) | LDD2205 | [17] |
LDCM0569 | Fragment7 | Ramos | C91(1.94) | LDD2186 | [17] |
LDCM0571 | Fragment9 | Ramos | C91(1.65) | LDD2188 | [17] |
LDCM0022 | KB02 | HCT 116 | C91(2.20) | LDD0080 | [4] |
LDCM0023 | KB03 | HCT 116 | C91(2.54) | LDD0081 | [4] |
LDCM0024 | KB05 | HCT 116 | C91(2.96) | LDD0082 | [4] |
LDCM0109 | NEM | HeLa | N.A. | LDD0223 | [12] |
LDCM0131 | RA190 | MM1.R | C91(1.46) | LDD0304 | [18] |
LDCM0112 | W16 | Hep-G2 | C91(0.60) | LDD0239 | [13] |
The Interaction Atlas With This Target
The Protein(s) Related To This Target
Enzyme
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
Ras-like protein family member 11B (RASL11B) | Ras family | Q9BPW5 |
Transcription factor
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
TOX high mobility group box family member 4 (TOX4) | . | O94842 |
Other
References