Details of the Target

General Information of Target

Target ID LDTP05698
Target Name TNF receptor-associated factor 2 (TRAF2)
Gene Name TRAF2
Gene ID 7186
Synonyms
TRAP3; TNF receptor-associated factor 2; EC 2.3.2.27; E3 ubiquitin-protein ligase TRAF2; RING-type E3 ubiquitin transferase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
KNSYVRDDAIFIKAIVDLTGL
Target Bioclass
Enzyme
Family
TNF receptor-associated factor family, A subfamily
Subcellular location
Cytoplasm
Function
Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation; this does not depend on the TRAF2 RING-type zinc finger domain. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. In complex with BIRC2 or BIRC3, promotes ubiquitination of IKBKE.
Uniprot ID
Q12933
Ensemble ID
ENST00000247668.7
HGNC ID
HGNC:12032

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AU565 SNV: p.K481N DBIA    Probe Info 
HCC1954 SNV: p.Q457L DBIA    Probe Info 
HCT15 SNV: p.A245T; p.R305L DBIA    Probe Info 
IPC298 SNV: p.P169L DBIA    Probe Info 
JURKAT SNV: p.C216Y .
LNCaP clone FGC SNV: p.H263R DBIA    Probe Info 
MEWO SNV: p.P186S DBIA    Probe Info 
MOLT4 SNV: p.I373T IA-alkyne    Probe Info 
NCIH196 SNV: p.E120A DBIA    Probe Info 
NCIH716 SNV: p.R241G .
RKO SNV: p.N482D DBIA    Probe Info 
RVH421 SNV: p.G259A DBIA    Probe Info 
SNGM SNV: p.Y53C DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 20 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
STPyne
 Probe Info  		K320(7.14)  LDD0277  [2]
BTD
 Probe Info  		C182(0.63)  LDD2091  [3]
AHL-Pu-1
 Probe Info  		C287(3.38)  LDD0169  [4]
DBIA
 Probe Info  		C287(2.36); C112(1.87); C170(2.28); C171(2.28)  LDD0080  [5]
4-Iodoacetamidophenylacetylene
 Probe Info  		C223(0.00); C303(0.00); C287(0.00)  LDD0038  [6]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [7]
Lodoacetamide azide
 Probe Info  		C223(0.00); C303(0.00); C182(0.00); C469(0.00)  LDD0037  [6]
NAIA_4
 Probe Info  		N.A.  LDD2226  [8]
TFBX
 Probe Info  		N.A.  LDD0027  [9]
WYneN
 Probe Info  		N.A.  LDD0021  [10]
aHNE
 Probe Info  		N.A.  LDD0001  [10]
ENE
 Probe Info  		N.A.  LDD0006  [10]
IPM
 Probe Info  		N.A.  LDD0005  [10]
Phosphinate-6
 Probe Info  		C287(0.00); C171(0.00); C124(0.00)  LDD0018  [11]
Acrolein
 Probe Info  		C124(0.00); C182(0.00); C156(0.00); C303(0.00)  LDD0217  [12]
Methacrolein
 Probe Info  		C124(0.00); C182(0.00); C156(0.00); C303(0.00)  LDD0218  [12]
W1
 Probe Info  		N.A.  LDD0236  [13]
AOyne
 Probe Info  		11.70  LDD0443  [14]
NAIA_5
 Probe Info  		C182(0.00); C107(0.00); C223(0.00); C49(0.00)  LDD2223  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C303(0.65); C182(0.79)  LDD2117  [3]
 LDCM0025  4SU-RNA HEK-293T C124(2.78)  LDD0172  [4]
 LDCM0026  4SU-RNA+native RNA HEK-293T C287(3.38)  LDD0169  [4]
 LDCM0214  AC1 HCT 116 C107(0.92); C112(0.91); C129(0.95); C170(1.04)  LDD0531  [5]
 LDCM0215  AC10 HCT 116 C107(1.06); C112(1.06); C129(0.90); C171(0.93)  LDD0532  [5]
 LDCM0216  AC100 HCT 116 C107(0.91); C112(0.89); C223(1.27); C287(1.07)  LDD0533  [5]
 LDCM0217  AC101 HCT 116 C107(0.91); C112(0.87); C223(1.26); C287(0.63)  LDD0534  [5]
 LDCM0218  AC102 HCT 116 C107(1.02); C112(0.94); C223(1.04); C287(0.71)  LDD0535  [5]
 LDCM0219  AC103 HCT 116 C107(1.15); C112(1.12); C223(1.37); C287(0.88)  LDD0536  [5]
 LDCM0220  AC104 HCT 116 C107(1.07); C112(1.00); C223(1.02); C287(0.54)  LDD0537  [5]
 LDCM0221  AC105 HCT 116 C107(1.03); C112(1.03); C223(1.08); C287(0.96)  LDD0538  [5]
 LDCM0222  AC106 HCT 116 C107(1.08); C112(1.08); C223(1.37); C287(1.15)  LDD0539  [5]
 LDCM0223  AC107 HCT 116 C107(1.08); C112(1.01); C223(1.09); C287(0.85)  LDD0540  [5]
 LDCM0224  AC108 HCT 116 C107(1.00); C112(0.97); C223(1.24); C287(0.65)  LDD0541  [5]
 LDCM0225  AC109 HCT 116 C107(0.96); C112(0.91); C223(1.02); C287(1.03)  LDD0542  [5]
 LDCM0226  AC11 HCT 116 C107(1.31); C112(1.32); C129(1.18); C171(1.27)  LDD0543  [5]
 LDCM0227  AC110 HCT 116 C107(1.11); C112(1.06); C223(1.40); C287(1.05)  LDD0544  [5]
 LDCM0228  AC111 HCT 116 C107(1.05); C112(1.03); C223(1.61); C287(1.02)  LDD0545  [5]
 LDCM0229  AC112 HCT 116 C107(1.23); C112(1.07); C223(1.35); C287(0.81)  LDD0546  [5]
 LDCM0230  AC113 HCT 116 C107(1.07); C112(1.08); C171(0.79); C223(0.99)  LDD0547  [5]
 LDCM0231  AC114 HCT 116 C107(1.15); C112(1.09); C171(0.79); C223(1.12)  LDD0548  [5]
 LDCM0232  AC115 HCT 116 C107(1.28); C112(1.26); C171(0.76); C223(1.34)  LDD0549  [5]
 LDCM0233  AC116 HCT 116 C107(1.24); C112(1.23); C171(0.92); C223(1.31)  LDD0550  [5]
 LDCM0234  AC117 HCT 116 C107(1.15); C112(1.21); C171(0.67); C223(1.15)  LDD0551  [5]
 LDCM0235  AC118 HCT 116 C107(1.24); C112(1.23); C171(0.77); C223(1.31)  LDD0552  [5]
 LDCM0236  AC119 HCT 116 C107(1.24); C112(1.22); C171(0.82); C223(1.17)  LDD0553  [5]
 LDCM0237  AC12 HCT 116 C107(0.94); C112(0.95); C129(1.05); C171(1.00)  LDD0554  [5]
 LDCM0238  AC120 HCT 116 C107(1.20); C112(1.08); C171(0.92); C223(1.26)  LDD0555  [5]
 LDCM0239  AC121 HCT 116 C107(1.23); C112(1.22); C171(0.69); C223(1.15)  LDD0556  [5]
 LDCM0240  AC122 HCT 116 C107(1.19); C112(1.15); C171(0.80); C223(1.20)  LDD0557  [5]
 LDCM0241  AC123 HCT 116 C107(1.01); C112(1.03); C171(0.68); C223(1.20)  LDD0558  [5]
 LDCM0242  AC124 HCT 116 C107(1.00); C112(0.96); C171(0.70); C223(0.96)  LDD0559  [5]
 LDCM0243  AC125 HCT 116 C107(1.10); C112(0.95); C171(0.59); C223(1.31)  LDD0560  [5]
 LDCM0244  AC126 HCT 116 C107(1.25); C112(1.19); C171(0.58); C223(1.69)  LDD0561  [5]
 LDCM0245  AC127 HCT 116 C107(1.14); C112(1.12); C171(0.64); C223(1.26)  LDD0562  [5]
 LDCM0246  AC128 HCT 116 C107(0.99); C112(1.04); C223(1.15); C34(0.87)  LDD0563  [5]
 LDCM0247  AC129 HCT 116 C107(0.62); C112(0.69); C223(0.76); C34(0.99)  LDD0564  [5]
 LDCM0249  AC130 HCT 116 C107(0.82); C112(0.87); C223(0.90); C34(0.94)  LDD0566  [5]
 LDCM0250  AC131 HCT 116 C107(0.69); C112(0.74); C223(0.68); C34(0.68)  LDD0567  [5]
 LDCM0251  AC132 HCT 116 C107(0.72); C112(0.78); C223(0.71); C34(0.77)  LDD0568  [5]
 LDCM0252  AC133 HCT 116 C107(0.90); C112(0.97); C223(0.83); C34(0.88)  LDD0569  [5]
 LDCM0253  AC134 HCT 116 C107(0.86); C112(0.98); C223(0.99); C34(0.90)  LDD0570  [5]
 LDCM0254  AC135 HCT 116 C107(0.78); C112(0.85); C223(0.92); C34(0.75)  LDD0571  [5]
 LDCM0255  AC136 HCT 116 C107(0.80); C112(0.87); C223(0.83); C34(1.04)  LDD0572  [5]
 LDCM0256  AC137 HCT 116 C107(0.83); C112(0.92); C223(0.80); C34(0.81)  LDD0573  [5]
 LDCM0257  AC138 HCT 116 C107(0.94); C112(1.02); C223(1.00); C34(0.89)  LDD0574  [5]
 LDCM0258  AC139 HCT 116 C107(0.74); C112(0.81); C223(0.98); C34(0.86)  LDD0575  [5]
 LDCM0259  AC14 HCT 116 C107(1.08); C112(1.08); C129(1.13); C171(0.97)  LDD0576  [5]
 LDCM0260  AC140 HCT 116 C107(0.98); C112(1.08); C223(1.01); C34(1.01)  LDD0577  [5]
 LDCM0261  AC141 HCT 116 C107(0.88); C112(0.97); C223(0.95); C34(0.95)  LDD0578  [5]
 LDCM0262  AC142 HCT 116 C107(0.75); C112(0.82); C223(0.96); C34(0.78)  LDD0579  [5]
 LDCM0263  AC143 HCT 116 C34(0.82); C37(0.82); C129(0.91); C287(0.96)  LDD0580  [5]
 LDCM0264  AC144 HCT 116 C129(0.81); C49(0.83); C287(0.94); C37(1.00)  LDD0581  [5]
 LDCM0265  AC145 HCT 116 C129(0.75); C49(0.80); C287(0.91); C34(0.93)  LDD0582  [5]
 LDCM0266  AC146 HCT 116 C129(0.77); C287(0.88); C34(0.89); C37(0.95)  LDD0583  [5]
 LDCM0267  AC147 HCT 116 C37(0.87); C49(0.90); C34(0.91); C129(0.91)  LDD0584  [5]
 LDCM0268  AC148 HCT 116 C287(0.84); C49(0.87); C129(0.90); C34(1.08)  LDD0585  [5]
 LDCM0269  AC149 HCT 116 C129(0.83); C49(0.93); C287(0.95); C34(1.04)  LDD0586  [5]
 LDCM0270  AC15 HCT 116 C303(0.88); C129(1.02); C34(1.02); C171(1.03)  LDD0587  [5]
 LDCM0271  AC150 HCT 116 C129(0.82); C287(0.88); C37(0.92); C34(0.93)  LDD0588  [5]
 LDCM0272  AC151 HCT 116 C129(0.83); C49(1.00); C37(1.12); C34(1.15)  LDD0589  [5]
 LDCM0273  AC152 HCT 116 C287(0.81); C129(0.85); C49(0.98); C34(1.03)  LDD0590  [5]
 LDCM0274  AC153 HCT 116 C287(0.89); C129(0.92); C49(1.03); C34(1.16)  LDD0591  [5]
 LDCM0621  AC154 HCT 116 C107(1.24); C112(1.21); C129(0.83); C171(1.27)  LDD2158  [5]
 LDCM0622  AC155 HCT 116 C107(1.29); C112(1.30); C129(0.88); C171(1.17)  LDD2159  [5]
 LDCM0623  AC156 HCT 116 C107(1.08); C112(1.07); C129(0.93); C171(2.28)  LDD2160  [5]
 LDCM0624  AC157 HCT 116 C107(1.06); C112(1.02); C129(0.85); C171(1.15)  LDD2161  [5]
 LDCM0276  AC17 HCT 116 C34(0.81); C37(0.81); C223(0.98); C107(1.02)  LDD0593  [5]
 LDCM0277  AC18 HCT 116 C34(0.77); C37(0.77); C303(0.84); C107(1.21)  LDD0594  [5]
 LDCM0278  AC19 HCT 116 C34(0.66); C37(0.66); C303(0.98); C223(1.00)  LDD0595  [5]
 LDCM0279  AC2 HCT 116 C107(0.86); C170(0.87); C49(0.89); C112(0.89)  LDD0596  [5]
 LDCM0280  AC20 HCT 116 C34(0.53); C37(0.53); C303(0.79); C107(1.02)  LDD0597  [5]
 LDCM0281  AC21 HCT 116 C34(0.73); C37(0.73); C303(0.79); C287(0.98)  LDD0598  [5]
 LDCM0282  AC22 HCT 116 C34(0.67); C37(0.67); C107(0.96); C223(0.99)  LDD0599  [5]
 LDCM0283  AC23 HCT 116 C34(0.76); C37(0.76); C107(0.99); C303(1.00)  LDD0600  [5]
 LDCM0284  AC24 HCT 116 C34(0.58); C37(0.58); C303(0.80); C287(0.90)  LDD0601  [5]
 LDCM0285  AC25 HCT 116 C287(0.86); C37(0.99); C49(1.01); C112(1.06)  LDD0602  [5]
 LDCM0286  AC26 HCT 116 C287(0.86); C37(1.07); C49(1.12); C112(1.15)  LDD0603  [5]
 LDCM0287  AC27 HCT 116 C287(0.79); C37(1.00); C49(1.07); C112(1.24)  LDD0604  [5]
 LDCM0288  AC28 HCT 116 C287(0.83); C37(0.92); C49(1.04); C112(1.19)  LDD0605  [5]
 LDCM0289  AC29 HCT 116 C287(0.80); C37(1.13); C223(1.15); C49(1.16)  LDD0606  [5]
 LDCM0290  AC3 HCT 116 C107(0.82); C37(0.83); C112(0.85); C34(0.86)  LDD0607  [5]
 LDCM0291  AC30 HCT 116 C287(0.94); C49(1.15); C37(1.25); C112(1.39)  LDD0608  [5]
 LDCM0292  AC31 HCT 116 C287(0.81); C49(0.97); C37(1.14); C112(1.27)  LDD0609  [5]
 LDCM0293  AC32 HCT 116 C287(0.79); C37(1.05); C49(1.08); C112(1.43)  LDD0610  [5]
 LDCM0294  AC33 HCT 116 C287(1.00); C49(1.11); C37(1.14); C112(1.49)  LDD0611  [5]
 LDCM0295  AC34 HCT 116 C287(0.85); C37(0.92); C49(1.18); C112(1.40)  LDD0612  [5]
 LDCM0296  AC35 HCT 116 C303(0.78); C223(0.81); C37(0.84); C49(0.86)  LDD0613  [5]
 LDCM0297  AC36 HCT 116 C303(0.67); C49(0.89); C223(0.90); C37(0.93)  LDD0614  [5]
 LDCM0298  AC37 HCT 116 C303(0.80); C223(0.80); C37(0.91); C287(0.98)  LDD0615  [5]
 LDCM0299  AC38 HCT 116 C303(0.76); C223(0.90); C49(0.92); C37(0.94)  LDD0616  [5]
 LDCM0300  AC39 HCT 116 C287(0.83); C171(0.86); C37(0.90); C34(0.98)  LDD0617  [5]
 LDCM0301  AC4 HCT 116 C37(0.71); C107(0.72); C112(0.76); C34(0.77)  LDD0618  [5]
 LDCM0302  AC40 HCT 116 C303(0.80); C37(0.87); C34(0.90); C223(0.99)  LDD0619  [5]
 LDCM0303  AC41 HCT 116 C303(0.75); C49(0.92); C223(0.98); C34(1.03)  LDD0620  [5]
 LDCM0304  AC42 HCT 116 C303(0.68); C49(0.87); C287(0.93); C107(1.03)  LDD0621  [5]
 LDCM0305  AC43 HCT 116 C303(0.75); C49(0.91); C34(0.95); C287(1.12)  LDD0622  [5]
 LDCM0306  AC44 HCT 116 C303(0.71); C34(0.84); C37(0.97); C223(0.98)  LDD0623  [5]
 LDCM0307  AC45 HCT 116 C303(0.77); C34(1.04); C223(1.12); C37(1.15)  LDD0624  [5]
 LDCM0308  AC46 HCT 116 C34(0.92); C49(0.92); C112(0.97); C107(1.02)  LDD0625  [5]
 LDCM0309  AC47 HCT 116 C34(0.94); C303(0.94); C112(0.99); C287(1.02)  LDD0626  [5]
 LDCM0310  AC48 HCT 116 C112(0.96); C34(0.97); C129(1.01); C49(1.04)  LDD0627  [5]
 LDCM0311  AC49 HCT 116 C34(0.92); C129(1.05); C170(1.06); C171(1.06)  LDD0628  [5]
 LDCM0312  AC5 HCT 116 C37(0.72); C34(0.78); C223(0.82); C129(0.88)  LDD0629  [5]
 LDCM0313  AC50 HCT 116 C129(0.87); C171(0.93); C170(0.94); C303(0.94)  LDD0630  [5]
 LDCM0314  AC51 HCT 116 C112(0.88); C303(0.94); C49(0.99); C34(1.00)  LDD0631  [5]
 LDCM0315  AC52 HCT 116 C34(0.87); C223(1.00); C129(1.00); C287(1.00)  LDD0632  [5]
 LDCM0316  AC53 HCT 116 C34(0.75); C112(1.03); C107(1.04); C303(1.09)  LDD0633  [5]
 LDCM0317  AC54 HCT 116 C287(0.84); C129(0.97); C303(0.98); C34(1.01)  LDD0634  [5]
 LDCM0318  AC55 HCT 116 C34(0.83); C112(1.30); C223(1.32); C107(1.34)  LDD0635  [5]
 LDCM0319  AC56 HCT 116 C34(1.03); C287(1.06); C129(1.23); C49(1.41)  LDD0636  [5]
 LDCM0320  AC57 HCT 116 C34(0.73); C37(0.73); C171(1.09); C107(1.13)  LDD0637  [5]
 LDCM0321  AC58 HCT 116 C34(0.67); C37(0.67); C171(1.00); C303(1.04)  LDD0638  [5]
 LDCM0322  AC59 HCT 116 C303(0.79); C34(0.87); C37(0.87); C107(1.10)  LDD0639  [5]
 LDCM0323  AC6 HCT 116 C303(0.93); C171(0.93); C37(1.00); C34(1.00)  LDD0640  [5]
 LDCM0324  AC60 HCT 116 C34(0.69); C37(0.69); C303(0.88); C107(1.08)  LDD0641  [5]
 LDCM0325  AC61 HCT 116 C34(0.75); C37(0.75); C303(0.81); C49(1.06)  LDD0642  [5]
 LDCM0326  AC62 HCT 116 C34(0.71); C37(0.71); C303(0.86); C49(1.25)  LDD0643  [5]
 LDCM0327  AC63 HCT 116 C303(0.57); C34(0.81); C37(0.81); C112(1.04)  LDD0644  [5]
 LDCM0328  AC64 HCT 116 C303(0.60); C34(0.79); C37(0.79); C107(1.14)  LDD0645  [5]
 LDCM0329  AC65 HCT 116 C34(0.68); C37(0.68); C303(0.69); C107(1.01)  LDD0646  [5]
 LDCM0330  AC66 HCT 116 C303(0.58); C34(0.72); C37(0.72); C107(0.98)  LDD0647  [5]
 LDCM0331  AC67 HCT 116 C34(0.72); C37(0.72); C303(0.79); C107(1.13)  LDD0648  [5]
 LDCM0332  AC68 HCT 116 C171(0.84); C170(0.87); C287(0.88); C303(0.89)  LDD0649  [5]
 LDCM0333  AC69 HCT 116 C170(0.78); C171(0.80); C287(0.90); C49(0.92)  LDD0650  [5]
 LDCM0334  AC7 HCT 116 C223(0.99); C129(0.99); C303(1.00); C37(1.01)  LDD0651  [5]
 LDCM0335  AC70 HCT 116 C171(0.81); C170(0.82); C49(0.97); C107(0.99)  LDD0652  [5]
 LDCM0336  AC71 HCT 116 C171(0.78); C223(0.80); C170(0.81); C107(0.88)  LDD0653  [5]
 LDCM0337  AC72 HCT 116 C170(0.80); C171(0.81); C287(0.97); C34(1.05)  LDD0654  [5]
 LDCM0338  AC73 HCT 116 C171(0.94); C170(1.01); C49(1.08); C34(1.11)  LDD0655  [5]
 LDCM0339  AC74 HCT 116 C170(0.80); C171(0.86); C34(1.07); C37(1.07)  LDD0656  [5]
 LDCM0340  AC75 HCT 116 C170(0.84); C171(0.90); C287(1.09); C34(1.12)  LDD0657  [5]
 LDCM0341  AC76 HCT 116 C170(0.72); C171(0.79); C49(1.02); C223(1.05)  LDD0658  [5]
 LDCM0342  AC77 HCT 116 C303(0.86); C171(0.90); C170(0.96); C287(1.01)  LDD0659  [5]
 LDCM0343  AC78 HCT 116 C49(0.79); C107(0.93); C171(0.95); C223(0.96)  LDD0660  [5]
 LDCM0344  AC79 HCT 116 C171(0.85); C49(0.86); C170(0.88); C107(0.95)  LDD0661  [5]
 LDCM0345  AC8 HCT 116 C129(0.99); C107(1.00); C112(1.02); C303(1.04)  LDD0662  [5]
 LDCM0346  AC80 HCT 116 C223(0.89); C170(1.00); C171(1.01); C49(1.05)  LDD0663  [5]
 LDCM0347  AC81 HCT 116 C171(0.79); C170(0.81); C49(0.88); C223(0.96)  LDD0664  [5]
 LDCM0348  AC82 HCT 116 C171(0.89); C170(0.90); C49(1.04); C287(1.06)  LDD0665  [5]
 LDCM0349  AC83 HCT 116 C37(0.94); C34(0.98); C129(1.03); C49(1.19)  LDD0666  [5]
 LDCM0350  AC84 HCT 116 C37(0.87); C34(1.00); C129(1.11); C49(1.13)  LDD0667  [5]
 LDCM0351  AC85 HCT 116 C37(0.87); C34(0.94); C107(1.12); C112(1.20)  LDD0668  [5]
 LDCM0352  AC86 HCT 116 C34(0.97); C37(0.99); C112(1.10); C129(1.13)  LDD0669  [5]
 LDCM0353  AC87 HCT 116 C37(0.89); C49(0.94); C34(0.94); C107(1.02)  LDD0670  [5]
 LDCM0354  AC88 HCT 116 C171(0.99); C129(1.07); C112(1.11); C34(1.13)  LDD0671  [5]
 LDCM0355  AC89 HCT 116 C34(1.05); C129(1.08); C37(1.08); C107(1.13)  LDD0672  [5]
 LDCM0357  AC90 HCT 116 C37(0.81); C34(0.96); C107(0.97); C112(0.98)  LDD0674  [5]
 LDCM0358  AC91 HCT 116 C34(1.06); C37(1.09); C129(1.15); C171(1.26)  LDD0675  [5]
 LDCM0359  AC92 HCT 116 C34(1.02); C37(1.06); C49(1.11); C129(1.24)  LDD0676  [5]
 LDCM0360  AC93 HCT 116 C34(0.99); C37(0.99); C112(1.08); C49(1.12)  LDD0677  [5]
 LDCM0361  AC94 HCT 116 C34(0.97); C37(1.03); C49(1.05); C107(1.10)  LDD0678  [5]
 LDCM0362  AC95 HCT 116 C37(0.83); C34(0.94); C49(0.98); C107(1.00)  LDD0679  [5]
 LDCM0363  AC96 HCT 116 C49(0.88); C37(0.90); C34(0.97); C223(1.04)  LDD0680  [5]
 LDCM0364  AC97 HCT 116 C37(1.03); C34(1.09); C107(1.26); C112(1.27)  LDD0681  [5]
 LDCM0365  AC98 HCT 116 C37(0.68); C287(0.84); C34(0.87); C107(1.07)  LDD0682  [5]
 LDCM0366  AC99 HCT 116 C37(0.75); C112(0.87); C107(0.90); C34(0.94)  LDD0683  [5]
 LDCM0545  Acetamide MDA-MB-231 C124(0.84)  LDD2138  [3]
 LDCM0248  AKOS034007472 HCT 116 C107(0.93); C112(0.94); C129(1.01); C171(0.96)  LDD0565  [5]
 LDCM0356  AKOS034007680 HCT 116 C34(0.96); C303(0.98); C37(0.98); C107(1.08)  LDD0673  [5]
 LDCM0275  AKOS034007705 HCT 116 C303(0.83); C171(0.94); C129(1.09); C34(1.14)  LDD0592  [5]
 LDCM0156  Aniline NCI-H1299 11.90  LDD0403  [1]
 LDCM0498  BS-3668 MDA-MB-231 C182(0.63)  LDD2091  [3]
 LDCM0108  Chloroacetamide HeLa C182(0.00); C223(0.00); C124(0.00); C303(0.00)  LDD0222  [12]
 LDCM0632  CL-Sc Hep-G2 C287(1.93); C287(0.60)  LDD2227  [8]
 LDCM0367  CL1 HCT 116 C37(0.78); C34(0.87); C129(0.91); C49(0.93)  LDD0684  [5]
 LDCM0368  CL10 HCT 116 C34(0.90); C49(0.95); C287(0.99); C37(1.02)  LDD0685  [5]
 LDCM0369  CL100 HCT 116 C223(0.84); C107(0.89); C112(0.89); C37(0.89)  LDD0686  [5]
 LDCM0370  CL101 HCT 116 C303(0.52); C171(1.02); C287(1.03); C129(1.06)  LDD0687  [5]
 LDCM0371  CL102 HCT 116 C303(0.47); C171(0.86); C34(0.92); C37(0.95)  LDD0688  [5]
 LDCM0372  CL103 HCT 116 C303(0.61); C49(0.93); C37(1.02); C171(1.04)  LDD0689  [5]
 LDCM0373  CL104 HCT 116 C303(0.71); C34(0.91); C37(0.95); C107(0.96)  LDD0690  [5]
 LDCM0374  CL105 HCT 116 C34(0.75); C37(0.75); C287(1.04); C303(1.15)  LDD0691  [5]
 LDCM0375  CL106 HCT 116 C34(1.03); C37(1.03); C287(1.12); C107(1.23)  LDD0692  [5]
 LDCM0376  CL107 HCT 116 C34(0.82); C37(0.82); C287(1.18); C107(1.20)  LDD0693  [5]
 LDCM0377  CL108 HCT 116 C34(0.81); C37(0.81); C287(1.03); C107(1.16)  LDD0694  [5]
 LDCM0378  CL109 HCT 116 C34(0.68); C37(0.68); C107(1.11); C112(1.18)  LDD0695  [5]
 LDCM0379  CL11 HCT 116 C129(0.79); C49(0.79); C37(0.98); C34(1.03)  LDD0696  [5]
 LDCM0380  CL110 HCT 116 C34(0.64); C37(0.64); C49(1.01); C107(1.06)  LDD0697  [5]
 LDCM0381  CL111 HCT 116 C34(0.67); C37(0.67); C107(1.00); C112(1.08)  LDD0698  [5]
 LDCM0382  CL112 HCT 116 C287(0.77); C49(0.84); C37(0.95); C107(1.03)  LDD0699  [5]
 LDCM0383  CL113 HCT 116 C287(0.81); C37(1.02); C49(1.12); C112(1.30)  LDD0700  [5]
 LDCM0384  CL114 HCT 116 C287(0.91); C37(0.91); C49(1.05); C112(1.16)  LDD0701  [5]
 LDCM0385  CL115 HCT 116 C49(1.03); C37(1.19); C287(1.23); C112(1.24)  LDD0702  [5]
 LDCM0386  CL116 HCT 116 C37(0.92); C287(1.03); C49(1.07); C223(1.21)  LDD0703  [5]
 LDCM0387  CL117 HCT 116 C303(0.56); C34(0.84); C287(0.87); C37(0.99)  LDD0704  [5]
 LDCM0388  CL118 HCT 116 C303(0.83); C171(0.96); C37(1.01); C49(1.01)  LDD0705  [5]
 LDCM0389  CL119 HCT 116 C303(0.87); C287(0.92); C49(0.98); C171(1.02)  LDD0706  [5]
 LDCM0390  CL12 HCT 116 C49(0.96); C129(0.99); C34(1.04); C287(1.04)  LDD0707  [5]
 LDCM0391  CL120 HCT 116 C303(0.83); C49(0.94); C223(1.02); C37(1.04)  LDD0708  [5]
 LDCM0392  CL121 HCT 116 C34(0.97); C49(1.02); C287(1.12); C129(1.16)  LDD0709  [5]
 LDCM0393  CL122 HCT 116 C49(0.98); C34(0.99); C112(1.00); C107(1.01)  LDD0710  [5]
 LDCM0394  CL123 HCT 116 C49(0.96); C303(0.98); C34(1.01); C112(1.02)  LDD0711  [5]
 LDCM0395  CL124 HCT 116 C34(0.75); C49(1.11); C112(1.14); C287(1.15)  LDD0712  [5]
 LDCM0396  CL125 HCT 116 C34(0.69); C37(0.69); C107(0.88); C112(0.97)  LDD0713  [5]
 LDCM0397  CL126 HCT 116 C34(0.65); C37(0.65); C303(0.80); C112(1.06)  LDD0714  [5]
 LDCM0398  CL127 HCT 116 C34(0.71); C37(0.71); C303(0.94); C107(0.96)  LDD0715  [5]
 LDCM0399  CL128 HCT 116 C34(0.72); C37(0.72); C303(1.06); C171(1.16)  LDD0716  [5]
 LDCM0400  CL13 HCT 116 C287(0.90); C37(0.94); C49(0.96); C34(0.98)  LDD0717  [5]
 LDCM0401  CL14 HCT 116 C49(0.92); C129(1.02); C107(1.03); C223(1.04)  LDD0718  [5]
 LDCM0402  CL15 HCT 116 C287(0.85); C129(0.86); C49(0.87); C37(0.89)  LDD0719  [5]
 LDCM0403  CL16 HCT 116 C171(0.94); C112(1.09); C129(1.14); C107(1.15)  LDD0720  [5]
 LDCM0404  CL17 HCT 116 C129(0.78); C34(0.94); C37(0.95); C287(1.00)  LDD0721  [5]
 LDCM0405  CL18 HCT 116 C171(0.91); C129(0.94); C170(1.03); C287(1.08)  LDD0722  [5]
 LDCM0406  CL19 HCT 116 C171(0.86); C287(0.90); C129(0.96); C49(1.05)  LDD0723  [5]
 LDCM0407  CL2 HCT 116 C34(0.94); C107(0.96); C49(0.98); C112(0.99)  LDD0724  [5]
 LDCM0408  CL20 HCT 116 C171(0.99); C129(1.03); C287(1.08); C170(1.20)  LDD0725  [5]
 LDCM0409  CL21 HCT 116 C129(0.82); C171(0.86); C49(1.01); C170(1.02)  LDD0726  [5]
 LDCM0410  CL22 HCT 116 C287(0.94); C171(0.96); C129(1.04); C49(1.12)  LDD0727  [5]
 LDCM0411  CL23 HCT 116 C170(0.90); C171(0.91); C129(1.00); C287(1.05)  LDD0728  [5]
 LDCM0412  CL24 HCT 116 C107(1.39); C112(1.28); C129(1.04); C170(0.93)  LDD0729  [5]
 LDCM0413  CL25 HCT 116 C107(1.32); C112(1.19); C129(1.12); C170(0.96)  LDD0730  [5]
 LDCM0414  CL26 HCT 116 C107(1.29); C112(1.26); C129(0.96); C170(1.00)  LDD0731  [5]
 LDCM0415  CL27 HCT 116 C107(1.30); C112(1.20); C129(0.99); C170(1.14)  LDD0732  [5]
 LDCM0416  CL28 HCT 116 C107(1.42); C112(1.37); C129(1.09); C170(1.09)  LDD0733  [5]
 LDCM0417  CL29 HCT 116 C107(1.40); C112(1.29); C129(1.10); C170(1.06)  LDD0734  [5]
 LDCM0418  CL3 HCT 116 C107(1.06); C112(1.04); C129(1.00); C170(1.09)  LDD0735  [5]
 LDCM0419  CL30 HCT 116 C107(1.16); C112(1.13); C129(1.18); C170(0.88)  LDD0736  [5]
 LDCM0420  CL31 HCT 116 C107(1.07); C112(1.04); C129(1.05); C170(1.06)  LDD0737  [5]
 LDCM0421  CL32 HCT 116 C107(1.13); C112(1.17); C171(1.04); C223(1.20)  LDD0738  [5]
 LDCM0422  CL33 HCT 116 C107(1.00); C112(1.00); C171(1.65); C223(1.48)  LDD0739  [5]
 LDCM0423  CL34 HCT 116 C107(1.23); C112(1.45); C171(1.25); C223(1.45)  LDD0740  [5]
 LDCM0424  CL35 HCT 116 C107(1.16); C112(1.14); C171(0.91); C223(1.46)  LDD0741  [5]
 LDCM0425  CL36 HCT 116 C107(1.17); C112(1.27); C171(0.87); C223(1.42)  LDD0742  [5]
 LDCM0426  CL37 HCT 116 C107(1.22); C112(1.34); C171(1.02); C223(1.67)  LDD0743  [5]
 LDCM0428  CL39 HCT 116 C107(1.30); C112(1.41); C171(1.07); C223(1.29)  LDD0745  [5]
 LDCM0429  CL4 HCT 116 C107(1.02); C112(1.02); C129(1.11); C170(1.16)  LDD0746  [5]
 LDCM0430  CL40 HCT 116 C107(1.08); C112(1.06); C171(1.31); C223(1.36)  LDD0747  [5]
 LDCM0431  CL41 HCT 116 C107(1.04); C112(1.11); C171(0.93); C223(1.31)  LDD0748  [5]
 LDCM0432  CL42 HCT 116 C107(1.56); C112(1.68); C171(0.98); C223(2.01)  LDD0749  [5]
 LDCM0433  CL43 HCT 116 C107(1.30); C112(1.39); C171(0.94); C223(1.45)  LDD0750  [5]
 LDCM0434  CL44 HCT 116 C107(1.23); C112(1.31); C171(1.08); C223(1.52)  LDD0751  [5]
 LDCM0435  CL45 HCT 116 C107(1.32); C112(1.40); C171(0.78); C223(1.86)  LDD0752  [5]
 LDCM0436  CL46 HCT 116 C107(1.00); C112(0.99); C129(0.87); C170(0.82)  LDD0753  [5]
 LDCM0437  CL47 HCT 116 C107(0.90); C112(0.91); C129(0.94); C170(1.02)  LDD0754  [5]
 LDCM0438  CL48 HCT 116 C107(0.91); C112(0.94); C129(1.06); C170(1.35)  LDD0755  [5]
 LDCM0439  CL49 HCT 116 C107(0.98); C112(0.97); C129(1.02); C170(0.70)  LDD0756  [5]
 LDCM0440  CL5 HCT 116 C107(1.06); C112(1.06); C129(0.97); C170(1.19)  LDD0757  [5]
 LDCM0441  CL50 HCT 116 C107(0.98); C112(0.98); C129(1.06); C170(0.74)  LDD0758  [5]
 LDCM0442  CL51 HCT 116 C107(0.90); C112(0.93); C129(0.82); C170(0.80)  LDD0759  [5]
 LDCM0443  CL52 HCT 116 C107(1.05); C112(1.02); C129(0.99); C170(0.73)  LDD0760  [5]
 LDCM0444  CL53 HCT 116 C107(1.01); C112(1.00); C129(1.07); C170(0.79)  LDD0761  [5]
 LDCM0445  CL54 HCT 116 C107(1.07); C112(1.01); C129(1.00); C170(0.73)  LDD0762  [5]
 LDCM0446  CL55 HCT 116 C107(0.95); C112(0.95); C129(0.87); C170(0.72)  LDD0763  [5]
 LDCM0447  CL56 HCT 116 C107(1.03); C112(1.02); C129(1.00); C170(0.74)  LDD0764  [5]
 LDCM0448  CL57 HCT 116 C107(1.05); C112(1.04); C129(0.90); C170(0.67)  LDD0765  [5]
 LDCM0449  CL58 HCT 116 C107(0.86); C112(0.92); C129(1.01); C170(0.82)  LDD0766  [5]
 LDCM0450  CL59 HCT 116 C107(1.00); C112(1.01); C129(0.97); C170(0.81)  LDD0767  [5]
 LDCM0451  CL6 HCT 116 C107(1.10); C112(1.12); C129(1.09); C170(1.34)  LDD0768  [5]
 LDCM0452  CL60 HCT 116 C107(1.03); C112(1.01); C129(0.88); C170(0.86)  LDD0769  [5]
 LDCM0453  CL61 HCT 116 C107(0.97); C112(1.02); C223(1.11); C34(0.78)  LDD0770  [5]
 LDCM0454  CL62 HCT 116 C107(1.00); C112(1.11); C223(1.21); C34(0.98)  LDD0771  [5]
 LDCM0455  CL63 HCT 116 C107(1.21); C112(1.18); C223(1.23); C34(0.89)  LDD0772  [5]
 LDCM0456  CL64 HCT 116 C107(1.21); C112(1.19); C223(1.59); C34(0.77)  LDD0773  [5]
 LDCM0457  CL65 HCT 116 C107(0.99); C112(1.03); C223(1.18); C34(0.99)  LDD0774  [5]
 LDCM0458  CL66 HCT 116 C107(1.45); C112(1.34); C223(1.83); C34(1.14)  LDD0775  [5]
 LDCM0459  CL67 HCT 116 C107(1.33); C112(1.21); C223(1.54); C34(1.08)  LDD0776  [5]
 LDCM0460  CL68 HCT 116 C107(1.24); C112(1.14); C223(1.53); C34(0.79)  LDD0777  [5]
 LDCM0461  CL69 HCT 116 C107(1.01); C112(1.19); C223(1.35); C34(0.71)  LDD0778  [5]
 LDCM0462  CL7 HCT 116 C107(1.20); C112(1.19); C129(1.04); C170(1.49)  LDD0779  [5]
 LDCM0463  CL70 HCT 116 C107(1.14); C112(1.15); C223(1.27); C34(0.73)  LDD0780  [5]
 LDCM0464  CL71 HCT 116 C107(1.20); C112(1.18); C223(1.61); C34(0.88)  LDD0781  [5]
 LDCM0465  CL72 HCT 116 C107(1.17); C112(1.14); C223(1.20); C34(0.95)  LDD0782  [5]
 LDCM0466  CL73 HCT 116 C107(1.06); C112(1.13); C223(1.26); C34(0.84)  LDD0783  [5]
 LDCM0467  CL74 HCT 116 C107(1.15); C112(1.17); C223(1.51); C34(0.99)  LDD0784  [5]
 LDCM0469  CL76 HCT 116 C107(0.77); C112(0.78); C129(0.91); C223(1.23)  LDD0786  [5]
 LDCM0470  CL77 HCT 116 C107(0.62); C112(0.63); C129(0.86); C223(1.48)  LDD0787  [5]
 LDCM0471  CL78 HCT 116 C107(0.58); C112(0.59); C129(1.09); C223(1.24)  LDD0788  [5]
 LDCM0472  CL79 HCT 116 C107(0.74); C112(0.77); C129(1.04); C223(1.30)  LDD0789  [5]
 LDCM0473  CL8 HCT 116 C107(1.19); C112(1.21); C129(0.93); C170(1.19)  LDD0790  [5]
 LDCM0474  CL80 HCT 116 C107(1.22); C112(1.22); C129(0.95); C223(1.10)  LDD0791  [5]
 LDCM0475  CL81 HCT 116 C107(0.70); C112(0.73); C129(0.80); C223(1.24)  LDD0792  [5]
 LDCM0476  CL82 HCT 116 C107(0.82); C112(0.84); C129(0.85); C223(1.84)  LDD0793  [5]
 LDCM0477  CL83 HCT 116 C107(0.78); C112(0.78); C129(1.00); C223(1.52)  LDD0794  [5]
 LDCM0478  CL84 HCT 116 C107(0.85); C112(0.86); C129(0.87); C223(1.55)  LDD0795  [5]
 LDCM0479  CL85 HCT 116 C107(0.82); C112(0.83); C129(0.82); C223(1.18)  LDD0796  [5]
 LDCM0480  CL86 HCT 116 C107(0.72); C112(0.74); C129(0.88); C223(1.22)  LDD0797  [5]
 LDCM0481  CL87 HCT 116 C107(0.87); C112(0.89); C129(0.95); C223(1.36)  LDD0798  [5]
 LDCM0482  CL88 HCT 116 C107(0.97); C112(1.00); C129(0.81); C223(1.37)  LDD0799  [5]
 LDCM0483  CL89 HCT 116 C107(0.89); C112(0.90); C129(1.10); C223(2.30)  LDD0800  [5]
 LDCM0484  CL9 HCT 116 C107(1.17); C112(1.20); C129(1.00); C170(1.51)  LDD0801  [5]
 LDCM0485  CL90 HCT 116 C107(0.70); C112(0.71); C129(0.81); C223(2.53)  LDD0802  [5]
 LDCM0486  CL91 HCT 116 C107(0.78); C112(0.78); C129(0.89); C170(0.80)  LDD0803  [5]
 LDCM0487  CL92 HCT 116 C107(0.86); C112(0.86); C129(1.23); C170(0.86)  LDD0804  [5]
 LDCM0488  CL93 HCT 116 C107(0.78); C112(0.83); C129(0.83); C170(0.86)  LDD0805  [5]
 LDCM0489  CL94 HCT 116 C107(0.86); C112(0.83); C129(0.90); C170(1.03)  LDD0806  [5]
 LDCM0490  CL95 HCT 116 C107(0.62); C112(0.64); C129(0.82); C170(0.81)  LDD0807  [5]
 LDCM0491  CL96 HCT 116 C107(0.90); C112(0.90); C129(1.00); C170(0.89)  LDD0808  [5]
 LDCM0492  CL97 HCT 116 C107(0.91); C112(0.91); C129(0.94); C170(1.04)  LDD0809  [5]
 LDCM0493  CL98 HCT 116 C107(0.80); C112(0.77); C129(0.96); C170(0.98)  LDD0810  [5]
 LDCM0494  CL99 HCT 116 C107(0.93); C112(0.93); C129(0.94); C170(1.18)  LDD0811  [5]
 LDCM0634  CY-0357 Hep-G2 C124(0.89)  LDD2228  [8]
 LDCM0495  E2913 HEK-293T C156(1.01); C182(1.12); C49(0.88); C124(1.11)  LDD1698  [15]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C303(0.79); C182(0.77)  LDD1702  [3]
 LDCM0625  F8 Ramos C49(1.51); C303(1.46); C287(0.83)  LDD2187  [16]
 LDCM0572  Fragment10 Ramos C303(0.30)  LDD2189  [16]
 LDCM0573  Fragment11 Ramos C49(20.00); C303(0.52)  LDD2190  [16]
 LDCM0574  Fragment12 Ramos C303(0.29)  LDD2191  [16]
 LDCM0576  Fragment14 Ramos C49(1.05); C303(0.88)  LDD2193  [16]
 LDCM0579  Fragment20 Ramos C303(0.29)  LDD2194  [16]
 LDCM0582  Fragment23 Ramos C303(0.47)  LDD2196  [16]
 LDCM0578  Fragment27 Ramos C303(0.77)  LDD2197  [16]
 LDCM0586  Fragment28 Ramos C49(0.47); C303(0.73)  LDD2198  [16]
 LDCM0588  Fragment30 Ramos C303(0.57)  LDD2199  [16]
 LDCM0590  Fragment32 Ramos C303(0.31)  LDD2201  [16]
 LDCM0468  Fragment33 HCT 116 C107(1.31); C112(1.23); C223(1.68); C34(0.95)  LDD0785  [5]
 LDCM0596  Fragment38 Ramos C303(0.58)  LDD2203  [16]
 LDCM0566  Fragment4 Ramos C49(0.62); C303(0.85); C287(1.46)  LDD2184  [16]
 LDCM0427  Fragment51 HCT 116 C107(1.86); C112(1.91); C171(1.00); C223(2.06)  LDD0744  [5]
 LDCM0614  Fragment56 Ramos C303(0.59)  LDD2205  [16]
 LDCM0569  Fragment7 Ramos C49(0.49); C303(0.83); C287(0.65)  LDD2186  [16]
 LDCM0571  Fragment9 Ramos C303(0.32)  LDD2188  [16]
 LDCM0107  IAA HeLa C223(0.00); H151(0.00); C156(0.00)  LDD0221  [12]
 LDCM0022  KB02 HCT 116 C287(2.36); C112(1.87); C170(2.28); C171(2.28)  LDD0080  [5]
 LDCM0023  KB03 HCT 116 C287(2.15); C112(2.12); C170(1.47); C171(1.47)  LDD0081  [5]
 LDCM0024  KB05 HCT 116 C287(20.00); C112(1.82); C170(1.57); C171(1.57)  LDD0082  [5]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C182(1.27)  LDD2099  [3]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C303(0.82); C182(1.03)  LDD2109  [3]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C182(0.67)  LDD2111  [3]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C303(0.15); C182(1.99)  LDD2119  [3]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C223(1.21)  LDD2123  [3]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C303(1.06)  LDD2125  [3]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C303(1.23)  LDD2127  [3]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C303(0.36)  LDD2129  [3]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C303(0.66); C182(1.73)  LDD2140  [3]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C182(3.03)  LDD2144  [3]
 LDCM0112  W16 Hep-G2 C303(0.53)  LDD0239  [13]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 60 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) 5'-AMP-activated protein kinase beta subunit family O43741
Maspardin (SPG21) AB hydrolase superfamily Q9NZD8
Anterior gradient protein 2 homolog (AGR2) AGR family O95994
Glutamine--tRNA ligase (QARS1) Class-I aminoacyl-tRNA synthetase family P47897
Phenylalanine--tRNA ligase, mitochondrial (FARS2) Class-II aminoacyl-tRNA synthetase family O95363
Protein DDI1 homolog 1 (DDI1) DDI1 family Q8WTU0
Probable ATP-dependent RNA helicase DDX6 (DDX6) DEAD box helicase family P26196
Cryptochrome-2 (CRY2) DNA photolyase class-1 family Q49AN0
Dystrobrevin beta (DTNB) Dystrophin family O60941
Peroxisomal bifunctional enzyme (EHHADH) Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase family Q08426
DNA-directed RNA polymerase III subunit RPC3 (POLR3C) Eukaryotic RPC3/POLR3C RNA polymerase subunit family Q9BUI4
NADH-cytochrome b5 reductase 2 (CYB5R2) Flavoprotein pyridine nucleotide cytochrome reductase family Q6BCY4
Glutathione S-transferase P (GSTP1) Pi family P09211
Maleylacetoacetate isomerase (GSTZ1) Zeta family O43708
Baculoviral IAP repeat-containing protein 2 (BIRC2) IAP family Q13490
Baculoviral IAP repeat-containing protein 3 (BIRC3) IAP family Q13489
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) IMPDH/GMPR family P12268
Inositol hexakisphosphate kinase 3 (IP6K3) Inositol phosphokinase (IPK) family Q96PC2
eEF1A lysine and N-terminal methyltransferase (METTL13) Methyltransferase superfamily Q8N6R0
Small RNA 2'-O-methyltransferase (HENMT1) HEN1 family Q5T8I9
Methionine-R-sulfoxide reductase B2, mitochondrial (MSRB2) MsrB Met sulfoxide reductase family Q9Y3D2
Tudor-interacting repair regulator protein (NUDT16L1) Nudix hydrolase family Q9BRJ7
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (AASDHPPT) AcpS family Q9NRN7
Ubiquitin carboxyl-terminal hydrolase 2 (USP2) Peptidase C19 family O75604
Calpain-15 (CAPN15) Peptidase C2 family O75808
Tumor necrosis factor alpha-induced protein 3 (TNFAIP3) Peptidase C64 family P21580
Proteasome subunit beta type-1 (PSMB1) Peptidase T1B family P20618
26S proteasome non-ATPase regulatory subunit 9 (PSMD9) Proteasome subunit p27 family O00233
Serine/threonine-protein kinase N1 (PKN1) AGC Ser/Thr protein kinase family Q16512
Cyclin-dependent kinase 18 (CDK18) CMGC Ser/Thr protein kinase family Q07002
Proto-oncogene serine/threonine-protein kinase mos (MOS) Ser/Thr protein kinase family P00540
Serine/threonine-protein kinase TBK1 (TBK1) Ser/Thr protein kinase family Q9UHD2
Mitogen-activated protein kinase kinase kinase 14 (MAP3K14) STE Ser/Thr protein kinase family Q99558
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) STE Ser/Thr protein kinase family Q99683
Serine/threonine-protein kinase TAO3 (TAOK3) STE Ser/Thr protein kinase family Q9H2K8
TRAF2 and NCK-interacting protein kinase (TNIK) STE Ser/Thr protein kinase family Q9UKE5
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) TKL Ser/Thr protein kinase family Q13546
Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) TKL Ser/Thr protein kinase family O43353
Epidermal growth factor receptor (EGFR) Tyr protein kinase family P00533
Tyrosine-protein kinase Yes (YES1) Tyr protein kinase family P07947
GTP-binding protein GEM (GEM) RGK family P55040
Helicase ARIP4 (RAD54L2) SNF2/RAD54 helicase family Q9Y4B4
Thioredoxin (TXN) Thioredoxin family P10599
TNF receptor-associated factor 2 (TRAF2) TNF receptor-associated factor family Q12933
TNF receptor-associated factor 6 (TRAF6) TNF receptor-associated factor family Q9Y4K3
Kinesin-like protein KIFC3 (KIFC3) Kinesin family Q9BVG8
E3 ubiquitin-protein ligase TRIM50 (TRIM50) TRIM/RBCC family Q86XT4
Tripartite motif-containing protein 14 (TRIM14) TRIM/RBCC family Q14142
Tripartite motif-containing protein 42 (TRIM42) TRIM/RBCC family Q8IWZ5
Cell division cycle protein 20 homolog B (CDC20B) WD repeat CDC20/Fizzy family Q86Y33
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
E3 ubiquitin-protein ligase RNF146 (RNF146) . Q9NTX7
E3 ubiquitin-protein ligase RNF4 (RNF4) . P78317
Ferredoxin-fold anticodon-binding domain-containing protein 1 (FDXACB1) . Q9BRP7
LON peptidase N-terminal domain and RING finger protein 1 (LONRF1) . Q17RB8
LON peptidase N-terminal domain and RING finger protein 3 (LONRF3) . Q496Y0
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) . Q13526
Polycomb group RING finger protein 2 (PCGF2) . P35227
Polycomb group RING finger protein 5 (PCGF5) . Q86SE9
Probable E3 ubiquitin-protein ligase makorin-3 (MKRN3) . Q13064
Transporter and channel
Click To Hide/Show 8 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Anion exchange protein 3 (SLC4A3) Anion exchanger (TC 2.A.31) family P48751
Cation channel sperm-associated protein 1 (CATSPER1) Cation channel sperm-associated (TC 1.A.1.19) family Q8NEC5
Hsp90 co-chaperone Cdc37 (CDC37) CDC37 family Q16543
Germ cell-specific gene 1 protein (GSG1) GSG1 family Q2KHT4
Huntingtin (HTT) Huntingtin family P42858
Aquaporin-1 (AQP1) MIP/aquaporin (TC 1.A.8) family P29972
Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1) Ser/Thr protein kinase family O75460
Sodium channel modifier 1 (SCNM1) . Q9BWG6
Transcription factor
Click To Hide/Show 38 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
AF4/FMR2 family member 4 (AFF4) AF4 family Q9UHB7
Homeobox protein Hox-B5 (HOXB5) Antp homeobox family P09067
Homeobox protein Hox-A1 (HOXA1) Antp homeobox family P49639
Nuclear factor interleukin-3-regulated protein (NFIL3) BZIP family Q16649
Transcription factor COE2 (EBF2) COE family Q9HAK2
REST corepressor 3 (RCOR3) CoREST family Q9P2K3
Transcriptional repressor CTCF (CTCF) CTCF zinc-finger protein family P49711
Krueppel-like factor 3 (KLF3) Krueppel C2H2-type zinc-finger protein family P57682
Vascular endothelial zinc finger 1 (VEZF1) Krueppel C2H2-type zinc-finger protein family Q14119
Zinc finger and BTB domain-containing protein 16 (ZBTB16) Krueppel C2H2-type zinc-finger protein family Q05516
Zinc finger and BTB domain-containing protein 24 (ZBTB24) Krueppel C2H2-type zinc-finger protein family O43167
Zinc finger and BTB domain-containing protein 49 (ZBTB49) Krueppel C2H2-type zinc-finger protein family Q6ZSB9
Zinc finger and SCAN domain-containing protein 23 (ZSCAN23) Krueppel C2H2-type zinc-finger protein family Q3MJ62
Zinc finger and SCAN domain-containing protein 32 (ZSCAN32) Krueppel C2H2-type zinc-finger protein family Q9NX65
Zinc finger protein 35 (ZNF35) Krueppel C2H2-type zinc-finger protein family P13682
Zinc finger protein 417 (ZNF417) Krueppel C2H2-type zinc-finger protein family Q8TAU3
Zinc finger protein 438 (ZNF438) Krueppel C2H2-type zinc-finger protein family Q7Z4V0
Zinc finger protein 544 (ZNF544) Krueppel C2H2-type zinc-finger protein family Q6NX49
Zinc finger protein 572 (ZNF572) Krueppel C2H2-type zinc-finger protein family Q7Z3I7
Zinc finger protein 648 (ZNF648) Krueppel C2H2-type zinc-finger protein family Q5T619
Zinc finger protein 655 (ZNF655) Krueppel C2H2-type zinc-finger protein family Q8N720
Zinc finger protein 774 (ZNF774) Krueppel C2H2-type zinc-finger protein family Q6NX45
Zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3) Krueppel C2H2-type zinc-finger protein family Q9BRR0
NF-kappa-B inhibitor delta (NFKBID) NF-kappa-B inhibitor family Q8NI38
Nuclear respiratory factor 1 (NRF1) NRF1/Ewg family Q16656
Transcription factor RFX3 (RFX3) RFX family P48380
Zinc finger protein SNAI1 (SNAI1) Snail C2H2-type zinc-finger protein family O95863
Teashirt homolog 2 (TSHZ2) Teashirt C2H2-type zinc-finger protein family Q9NRE2
Teashirt homolog 3 (TSHZ3) Teashirt C2H2-type zinc-finger protein family Q63HK5
B-cell lymphoma 6 protein (BCL6) . P41182
Forkhead box protein N1 (FOXN1) . O15353
THAP domain-containing protein 7 (THAP7) . Q9BT49
Transcription factor SOX-13 (SOX13) . Q9UN79
Transcription factor SOX-3 (SOX3) . P41225
Transcriptional regulator QRICH1 (QRICH1) . Q2TAL8
Upstream stimulatory factor 1 (USF1) . P22415
Zinc finger and BTB domain-containing protein 25 (ZBTB25) . P24278
Zinc finger protein 410 (ZNF410) . Q86VK4
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Neuromedin-U receptor 2 (NMUR2) G-protein coupled receptor 1 family Q9GZQ4
Cytokine and receptor
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tumor necrosis factor receptor superfamily member 14 (TNFRSF14) Tumor necrosis factor receptor superfamily Q92956
Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A) . Q9Y6Q6
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) . Q9NP84
Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) . P20333
Tumor necrosis factor receptor superfamily member 5 (CD40) . P25942
Other
Click To Hide/Show 115 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Atos homolog protein B (ATOSB) ATOS family Q7L5A3
Ataxin-1 (ATXN1) ATXN1 family P54253
Protein BANP (BANP) BANP/SMAR1 family Q8N9N5
Beta-crystallin A2 (CRYBA2) Beta/gamma-crystallin family P53672
Protein BEX2 (BEX2) BEX family Q9BXY8
Biorientation of chromosomes in cell division protein 1-like 2 (BOD1L2) BOD1 family Q8IYS8
Bystin (BYSL) Bystin family Q13895
Cyclin-dependent kinase inhibitor 1B (CDKN1B) CDI family P46527
Constitutive coactivator of peroxisome proliferator-activated receptor gamma (FAM120B) Constitutive coactivator of PPAR-gamma family Q96EK7
CWF19-like protein 2 (CWF19L2) CWF19 family Q2TBE0
Cyclin-J-like protein (CCNJL) Cyclin family, Cyclin J subfamily Q8IV13
Dynein regulatory complex subunit 4 (GAS8) DRC4 family O95995
Segment polarity protein dishevelled homolog DVL-3 (DVL3) DSH family Q92997
ELL-associated factor 1 (EAF1) EAF family Q96JC9
Protein FAM161A (FAM161A) FAM161 family Q3B820
Protein FAM161B (FAM161B) FAM161 family Q96MY7
Protein FAM50B (FAM50B) FAM50 family Q9Y247
Protein FAM9A (FAM9A) FAM9 family Q8IZU1
Protein FAM90A1 (FAM90A1) FAM90 family Q86YD7
EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1) Fibulin family Q12805
Radial spoke head 14 homolog (RSPH14) Flagellar radial spoke RSP14 family Q9UHP6
GAS2-like protein 2 (GAS2L2) GAS2 family Q8NHY3
Hemoglobin subunit mu (HBM) Globin family Q6B0K9
Golgi reassembly-stacking protein 2 (GORASP2) GORASP family Q9H8Y8
Heat shock 70 kDa protein 12B (HSPA12B) Heat shock protein 70 family Q96MM6
Core histone macro-H2A.1 (MACROH2A1) Histone H2A family O75367
Zinc finger protein 488 (ZNF488) Krueppel C2H2-type zinc-finger protein family Q96MN9
Protein PALS1 (PALS1) MAGUK family Q8N3R9
Microfibrillar-associated protein 1 (MFAP1) MFAP1 family P55081
Mitotic interactor and substrate of PLK1 (MISP) MISP family Q8IVT2
G-patch domain and KOW motifs-containing protein (GPKOW) MOS2 family Q92917
NGFI-A-binding protein 2 (NAB2) NAB family Q15742
Protein NATD1 (NATD1) NATD1 family Q8N6N6
NHS-like protein 2 (NHSL2) NHS family Q5HYW2
Periplakin (PPL) Plakin or cytolinker family O60437
PRKR-interacting protein 1 (PRKRIP1) PRKRIP1 family Q9H875
Pre-mRNA-splicing factor 18 (PRPF18) PRP18 family Q99633
UV excision repair protein RAD23 homolog A (RAD23A) RAD23 family P54725
Ras and Rab interactor 1 (RIN1) RIN (Ras interaction/interference) family Q13671
Protein ripply1 (RIPPLY1) Ripply family Q0D2K3
Protein ripply3 (RIPPLY3) Ripply family P57055
RNA-binding protein EWS (EWSR1) RRM TET family Q01844
Actin-binding protein WASF1 (WASF1) SCAR/WAVE family Q92558
Nonsense-mediated mRNA decay factor SMG9 (SMG9) SMG9 family Q9H0W8
Synaptotagmin-17 (SYT17) Synaptotagmin family Q9BSW7
T-cell leukemia/lymphoma protein 1A (TCL1A) TCL1 family P56279
Tektin-3 (TEKT3) Tektin family Q9BXF9
Transcription elongation factor A protein 2 (TCEA2) TFS-II family Q15560
TRAF-interacting protein with FHA domain-containing protein A (TIFA) TIFA family Q96CG3
Tigger transposable element-derived protein 4 (TIGD4) Tigger transposable element derived protein family Q8IY51
TNF receptor-associated factor 5 (TRAF5) TNF receptor-associated factor family O00463
U5 small nuclear ribonucleoprotein TSSC4 (TSSC4) TSSC4 family Q9Y5U2
Small ubiquitin-related modifier 1 (SUMO1) Ubiquitin family P63165
Small ubiquitin-related modifier 5 (SUMO1P1) Ubiquitin family G2XKQ0
U3 small nucleolar RNA-associated protein 14 homolog C (UTP14C) UTP14 family Q5TAP6
rRNA-processing protein UTP23 homolog (UTP23) UTP23/FCF1 family Q9BRU9
Dematin (DMTN) Villin/gelsolin family Q08495
Bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) WAL family Q9UIF8
TLE family member 5 (TLE5) WD repeat Groucho/TLE family Q08117
Zinc finger C2HC domain-containing protein 1C (ZC2HC1C) ZC2HC1 family Q53FD0
Activating signal cointegrator 1 complex subunit 1 (ASCC1) . Q8N9N2
AN1-type zinc finger protein 6 (ZFAND6) . Q6FIF0
Axin-1 (AXIN1) . O15169
B-cell lymphoma/leukemia 10 (BCL10) . O95999
Bromo adjacent homology domain-containing 1 protein (BAHD1) . Q8TBE0
Cation channel sperm-associated targeting subunit tau (C2CD6) . Q53TS8
Cell division cycle-associated protein 3 (CDCA3) . Q99618
Chromobox protein homolog 8 (CBX8) . Q9HC52
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (CHCHD2) . Q9Y6H1
DCC-interacting protein 13-alpha (APPL1) . Q9UKG1
Ectodysplasin-A receptor-associated adapter protein (EDARADD) . Q8WWZ3
EF-hand domain-containing protein 1 (EFHC1) . Q5JVL4
Enkurin domain-containing protein 1 (ENKD1) . Q9H0I2
F-box only protein 28 (FBXO28) . Q9NVF7
Factor associated with metabolism and energy (CCDC198) . Q9NVL8
FLYWCH-type zinc finger-containing protein 1 (FLYWCH1) . Q4VC44
G patch domain and ankyrin repeat-containing protein 1 (GPANK1) . O95872
GA-binding protein subunit beta-1 (GABPB1) . Q06547
Genetic suppressor element 1 (GSE1) . Q14687
Grancalcin (GCA) . P28676
GRIP1-associated protein 1 (GRIPAP1) . Q4V328
INO80 complex subunit B (INO80B) . Q9C086
IQ motif and ubiquitin-like domain-containing protein (IQUB) . Q8NA54
KN motif and ankyrin repeat domain-containing protein 2 (KANK2) . Q63ZY3
Lamin tail domain-containing protein 2 (LMNTD2) . Q8IXW0
Leukocyte receptor cluster member 1 (LENG1) . Q96BZ8
LysM and putative peptidoglycan-binding domain-containing protein 1 (LYSMD1) . Q96S90
Mitochondrial antiviral-signaling protein (MAVS) . Q7Z434
MORN repeat-containing protein 3 (MORN3) . Q6PF18
Nebulette (NEBL) . O76041
Phostensin (PPP1R18) . Q6NYC8
PiggyBac transposable element-derived protein 1 (PGBD1) . Q96JS3
Protein phosphatase 1 regulatory subunit 26 (PPP1R26) . Q5T8A7
PSME3-interacting protein (PSME3IP1) . Q9GZU8
Putative ankyrin repeat domain-containing protein 26-like 1 (ANKRD36BP1) . Q96IX9
Putative uncharacterized protein LINC02875 (LINC02875) . Q86X59
Ras association domain-containing protein 5 (RASSF5) . Q8WWW0
Rho guanine nucleotide exchange factor 6 (ARHGEF6) . Q15052
RNA-binding protein 41 (RBM41) . Q96IZ5
SH2 domain-containing protein 4A (SH2D4A) . Q9H788
SHC-transforming protein 3 (SHC3) . Q92529
Sterile alpha motif domain-containing protein 11 (SAMD11) . Q96NU1
Tastin (TROAP) . Q12815
Telethonin (TCAP) . O15273
Testis-specific protein 10-interacting protein (TSGA10IP) . Q3SY00
TNF receptor-associated factor 1 (TRAF1) . Q13077
TRAF family member-associated NF-kappa-B activator (TANK) . Q92844
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) . Q15628
U11/U12 small nuclear ribonucleoprotein 25 kDa protein (SNRNP25) . Q9BV90
UBX domain-containing protein 11 (UBXN11) . Q5T124
Uncharacterized protein EXOC3-AS1 (EXOC3-AS1) . Q8N2X6
von Willebrand factor A domain-containing protein 2 (VWA2) . Q5GFL6
Zinc finger matrin-type protein 2 (ZMAT2) . Q96NC0
Zinc finger SWIM domain-containing protein 3 (ZSWIM3) . Q96MP5
ZZ-type zinc finger-containing protein 3 (ZZZ3) . Q8IYH5

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
10 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
11 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
12 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
13 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
14 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
15 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
16 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578