Details of the Target
General Information of Target
Target ID | LDTP12434 | |||||
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Target Name | Exosome complex component RRP40 (EXOSC3) | |||||
Gene Name | EXOSC3 | |||||
Gene ID | 51010 | |||||
Synonyms |
RRP40; Exosome complex component RRP40; Exosome component 3; Ribosomal RNA-processing protein 40; p10 |
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3D Structure | ||||||
Sequence |
MEEETHTDAKIRAENGTGSSPRGPGCSLRHFACEQNLLSRPDGSASFLQGDTSVLAGVYG
PAEVKVSKEIFNKATLEVILRPKIGLPGVAEKSRERLIRNTCEAVVLGTLHPRTSITVVL QVVSDAGSLLACCLNAACMALVDAGVPMRALFCGVACALDSDGTLVLDPTSKQEKEARAV LTFALDSVERKLLMSSTKGLYSDTELQQCLAAAQAASQHVFRFYRESLQRRYSKS |
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Target Bioclass |
Other
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Family |
RRP40 family
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Subcellular location |
Cytoplasm
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Function |
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC3 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC9 and EXOSC5.
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Uniprot ID | ||||||
Ensemble ID | ||||||
HGNC ID |
Target Site Mutations in Different Cell Lines
Cell line | Mutation details | Probe for labeling this protein in this cell | |||
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HCC1395 | SNV: p.K124N | DBIA Probe Info | |||
SNU5 | SNV: p.E32Ter | DBIA Probe Info |
Probe(s) Labeling This Target
ABPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
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m-APA Probe Info |
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15.00 | LDD0402 | [1] | |
TH211 Probe Info |
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Y100(6.59) | LDD0257 | [2] | |
STPyne Probe Info |
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K113(10.00); K82(1.82) | LDD0277 | [3] | |
BTD Probe Info |
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C67(2.02) | LDD1700 | [4] | |
AHL-Pu-1 Probe Info |
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C180(2.10) | LDD0171 | [5] | |
DBIA Probe Info |
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C215(0.99) | LDD0078 | [6] | |
ATP probe Probe Info |
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K113(0.00); K151(0.00) | LDD0199 | [7] | |
4-Iodoacetamidophenylacetylene Probe Info |
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C215(0.00); C257(0.00); C67(0.00) | LDD0038 | [8] | |
IA-alkyne Probe Info |
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C215(0.00); C257(0.00); C67(0.00) | LDD0036 | [8] | |
Lodoacetamide azide Probe Info |
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C215(0.00); C257(0.00); C67(0.00) | LDD0037 | [8] | |
NAIA_4 Probe Info |
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C215(0.00); C257(0.00) | LDD2226 | [9] | |
WYneN Probe Info |
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N.A. | LDD0021 | [10] | |
WYneO Probe Info |
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N.A. | LDD0022 | [10] | |
IPM Probe Info |
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N.A. | LDD0005 | [10] | |
TFBX Probe Info |
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C215(0.00); C67(0.00) | LDD0148 | [11] | |
VSF Probe Info |
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C215(0.00); C184(0.00) | LDD0007 | [10] | |
Phosphinate-6 Probe Info |
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C74(0.00); C83(0.00) | LDD0018 | [12] | |
Ox-W18 Probe Info |
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N.A. | LDD2175 | [13] | |
Acrolein Probe Info |
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C215(0.00); C184(0.00) | LDD0217 | [14] | |
Methacrolein Probe Info |
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N.A. | LDD0218 | [14] | |
W1 Probe Info |
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C215(0.00); C67(0.00) | LDD0236 | [15] | |
AOyne Probe Info |
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15.00 | LDD0443 | [16] | |
NAIA_5 Probe Info |
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C257(0.00); C215(0.00); C67(0.00) | LDD2223 | [9] |
PAL-AfBPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
---|---|---|---|---|---|
C219 Probe Info |
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5.43 | LDD1893 | [17] | |
FFF probe14 Probe Info |
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20.00 | LDD0477 | [18] | |
FFF probe3 Probe Info |
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8.11 | LDD0465 | [18] | |
VE-P Probe Info |
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N.A. | LDD0396 | [19] | |
OEA-DA Probe Info |
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5.41 | LDD0046 | [20] |
Competitor(s) Related to This Target
Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
---|---|---|---|---|---|
LDCM0548 | 1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one | MDA-MB-231 | C67(0.32) | LDD2142 | [4] |
LDCM0519 | 1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one | MDA-MB-231 | C215(1.00) | LDD2112 | [4] |
LDCM0537 | 2-Cyano-N,N-dimethylacetamide | MDA-MB-231 | C215(0.88) | LDD2130 | [4] |
LDCM0524 | 2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide | MDA-MB-231 | C67(0.75) | LDD2117 | [4] |
LDCM0558 | 2-Cyano-N-phenylacetamide | MDA-MB-231 | C67(1.03) | LDD2152 | [4] |
LDCM0539 | 3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile | MDA-MB-231 | C215(0.44) | LDD2132 | [4] |
LDCM0538 | 4-(Cyanoacetyl)morpholine | MDA-MB-231 | C215(0.95) | LDD2131 | [4] |
LDCM0026 | 4SU-RNA+native RNA | DM93 | C180(2.10) | LDD0171 | [5] |
LDCM0214 | AC1 | HCT 116 | C180(0.73); C184(0.82); C215(1.14); C67(1.06) | LDD0531 | [6] |
LDCM0215 | AC10 | HCT 116 | C180(0.75); C184(0.80); C215(1.10); C67(1.04) | LDD0532 | [6] |
LDCM0216 | AC100 | HCT 116 | C180(0.59); C184(0.70); C215(1.13); C67(0.88) | LDD0533 | [6] |
LDCM0217 | AC101 | HCT 116 | C180(0.51); C184(0.72); C215(1.06); C67(0.92) | LDD0534 | [6] |
LDCM0218 | AC102 | HCT 116 | C180(0.55); C184(0.68); C215(1.20); C67(0.88) | LDD0535 | [6] |
LDCM0219 | AC103 | HCT 116 | C180(0.43); C184(0.67); C215(1.52); C67(0.94) | LDD0536 | [6] |
LDCM0220 | AC104 | HCT 116 | C180(0.49); C184(0.66); C215(1.11); C67(0.83) | LDD0537 | [6] |
LDCM0221 | AC105 | HCT 116 | C180(0.48); C184(0.70); C215(1.42); C67(0.97) | LDD0538 | [6] |
LDCM0222 | AC106 | HCT 116 | C180(0.48); C184(0.66); C215(1.25); C67(0.99) | LDD0539 | [6] |
LDCM0223 | AC107 | HCT 116 | C180(0.51); C184(0.76); C215(1.53); C67(0.93) | LDD0540 | [6] |
LDCM0224 | AC108 | HCT 116 | C180(0.59); C184(0.73); C215(1.16); C67(0.93) | LDD0541 | [6] |
LDCM0225 | AC109 | HCT 116 | C180(0.58); C184(0.65); C215(0.93); C67(0.92) | LDD0542 | [6] |
LDCM0226 | AC11 | HCT 116 | C180(0.67); C184(0.76); C215(1.08); C67(1.12) | LDD0543 | [6] |
LDCM0227 | AC110 | HCT 116 | C180(0.56); C184(0.67); C215(1.24); C67(0.98) | LDD0544 | [6] |
LDCM0228 | AC111 | HCT 116 | C180(0.51); C184(0.71); C215(1.08); C67(1.01) | LDD0545 | [6] |
LDCM0229 | AC112 | HCT 116 | C180(0.50); C184(0.68); C215(1.24); C67(0.86) | LDD0546 | [6] |
LDCM0230 | AC113 | HCT 116 | C180(0.93); C184(1.04); C215(1.11); C67(1.40) | LDD0547 | [6] |
LDCM0231 | AC114 | HCT 116 | C180(0.82); C184(0.88); C215(1.47); C67(1.04) | LDD0548 | [6] |
LDCM0232 | AC115 | HCT 116 | C180(0.74); C184(0.94); C215(1.58); C67(1.00) | LDD0549 | [6] |
LDCM0233 | AC116 | HCT 116 | C180(0.70); C184(0.90); C215(1.69); C67(1.10) | LDD0550 | [6] |
LDCM0234 | AC117 | HCT 116 | C180(0.82); C184(1.00); C215(1.29); C67(1.34) | LDD0551 | [6] |
LDCM0235 | AC118 | HCT 116 | C180(0.91); C184(0.89); C215(1.26); C67(1.25) | LDD0552 | [6] |
LDCM0236 | AC119 | HCT 116 | C180(0.81); C184(0.93); C215(1.24); C67(1.20) | LDD0553 | [6] |
LDCM0237 | AC12 | HCT 116 | C180(0.92); C184(0.87); C215(0.96); C67(0.89) | LDD0554 | [6] |
LDCM0238 | AC120 | HCT 116 | C180(0.77); C184(0.82); C215(1.33); C67(1.19) | LDD0555 | [6] |
LDCM0239 | AC121 | HCT 116 | C180(1.08); C184(0.94); C215(1.20); C67(1.43) | LDD0556 | [6] |
LDCM0240 | AC122 | HCT 116 | C180(0.96); C184(1.02); C215(1.14); C67(1.14) | LDD0557 | [6] |
LDCM0241 | AC123 | HCT 116 | C180(1.17); C184(1.05); C215(1.09); C67(1.52) | LDD0558 | [6] |
LDCM0242 | AC124 | HCT 116 | C180(1.07); C184(1.04); C215(1.09); C67(1.14) | LDD0559 | [6] |
LDCM0243 | AC125 | HCT 116 | C180(0.96); C184(0.96); C215(1.26); C67(1.02) | LDD0560 | [6] |
LDCM0244 | AC126 | HCT 116 | C180(0.84); C184(0.80); C215(1.70); C67(1.32) | LDD0561 | [6] |
LDCM0245 | AC127 | HCT 116 | C180(0.82); C184(0.90); C215(1.55); C67(1.27) | LDD0562 | [6] |
LDCM0246 | AC128 | HCT 116 | C180(0.85); C184(1.05); C215(1.35); C67(1.20) | LDD0563 | [6] |
LDCM0247 | AC129 | HCT 116 | C180(1.28); C184(1.17); C215(0.93); C67(1.07) | LDD0564 | [6] |
LDCM0249 | AC130 | HCT 116 | C180(1.04); C184(1.09); C215(1.21); C67(1.02) | LDD0566 | [6] |
LDCM0250 | AC131 | HCT 116 | C180(1.32); C184(1.30); C215(0.99); C67(1.00) | LDD0567 | [6] |
LDCM0251 | AC132 | HCT 116 | C180(1.22); C184(1.16); C215(1.06); C67(1.02) | LDD0568 | [6] |
LDCM0252 | AC133 | HCT 116 | C180(0.93); C184(1.03); C215(1.17); C67(1.03) | LDD0569 | [6] |
LDCM0253 | AC134 | HCT 116 | C180(0.93); C184(1.17); C215(1.31); C67(1.13) | LDD0570 | [6] |
LDCM0254 | AC135 | HCT 116 | C180(0.97); C184(1.24); C215(1.25); C67(0.99) | LDD0571 | [6] |
LDCM0255 | AC136 | HCT 116 | C180(0.85); C184(0.97); C215(1.22); C67(1.24) | LDD0572 | [6] |
LDCM0256 | AC137 | HCT 116 | C180(0.88); C184(0.94); C215(1.08); C67(1.03) | LDD0573 | [6] |
LDCM0257 | AC138 | HCT 116 | C180(0.81); C184(1.18); C215(1.27); C67(1.15) | LDD0574 | [6] |
LDCM0258 | AC139 | HCT 116 | C180(0.88); C184(1.18); C215(1.25); C67(1.26) | LDD0575 | [6] |
LDCM0259 | AC14 | HCT 116 | C180(0.85); C184(0.91); C215(1.01); C67(0.99) | LDD0576 | [6] |
LDCM0260 | AC140 | HCT 116 | C180(0.88); C184(1.19); C215(1.39); C67(1.39) | LDD0577 | [6] |
LDCM0261 | AC141 | HCT 116 | C180(0.90); C184(1.22); C215(1.31); C67(1.13) | LDD0578 | [6] |
LDCM0262 | AC142 | HCT 116 | C180(1.34); C184(1.36); C215(1.02); C67(1.00) | LDD0579 | [6] |
LDCM0263 | AC143 | HCT 116 | C180(0.90); C184(0.91); C215(1.36); C67(0.84) | LDD0580 | [6] |
LDCM0264 | AC144 | HCT 116 | C180(0.66); C67(0.69); C184(0.79); C215(1.40) | LDD0581 | [6] |
LDCM0265 | AC145 | HCT 116 | C180(0.80); C67(0.83); C184(0.86); C215(1.14) | LDD0582 | [6] |
LDCM0266 | AC146 | HCT 116 | C67(0.68); C180(0.78); C184(0.95); C215(1.46) | LDD0583 | [6] |
LDCM0267 | AC147 | HCT 116 | C67(0.66); C180(0.68); C184(0.87); C215(1.41) | LDD0584 | [6] |
LDCM0268 | AC148 | HCT 116 | C67(0.65); C180(0.69); C184(0.92); C215(1.89) | LDD0585 | [6] |
LDCM0269 | AC149 | HCT 116 | C180(0.53); C67(0.59); C184(0.74); C215(1.61) | LDD0586 | [6] |
LDCM0270 | AC15 | HCT 116 | C180(0.65); C184(0.79); C67(1.05); C215(1.11) | LDD0587 | [6] |
LDCM0271 | AC150 | HCT 116 | C180(0.78); C67(0.83); C184(0.85); C215(1.12) | LDD0588 | [6] |
LDCM0272 | AC151 | HCT 116 | C180(0.78); C184(0.85); C67(0.89); C215(1.21) | LDD0589 | [6] |
LDCM0273 | AC152 | HCT 116 | C180(0.62); C67(0.69); C184(0.80); C215(1.49) | LDD0590 | [6] |
LDCM0274 | AC153 | HCT 116 | C180(0.59); C67(0.70); C184(0.93); C215(2.36) | LDD0591 | [6] |
LDCM0621 | AC154 | HCT 116 | C180(0.76); C184(0.92); C215(1.36); C67(0.78) | LDD2158 | [6] |
LDCM0622 | AC155 | HCT 116 | C180(0.85); C184(0.81); C215(1.45); C67(0.73) | LDD2159 | [6] |
LDCM0623 | AC156 | HCT 116 | C180(1.05); C184(0.95); C215(1.14); C67(0.96) | LDD2160 | [6] |
LDCM0624 | AC157 | HCT 116 | C180(1.36); C184(1.31); C215(1.04); C67(1.01) | LDD2161 | [6] |
LDCM0276 | AC17 | HCT 116 | C67(1.01); C184(1.04); C180(1.06); C215(1.13) | LDD0593 | [6] |
LDCM0277 | AC18 | HCT 116 | C180(0.70); C67(0.82); C184(0.92); C215(1.35) | LDD0594 | [6] |
LDCM0278 | AC19 | HCT 116 | C67(0.93); C180(0.94); C184(0.97); C215(1.09) | LDD0595 | [6] |
LDCM0279 | AC2 | HCT 116 | C180(0.77); C67(0.97); C184(1.00); C215(1.14) | LDD0596 | [6] |
LDCM0280 | AC20 | HCT 116 | C67(0.90); C180(0.96); C184(1.01); C215(1.09) | LDD0597 | [6] |
LDCM0281 | AC21 | HCT 116 | C67(0.77); C184(0.84); C180(0.92); C215(1.05) | LDD0598 | [6] |
LDCM0282 | AC22 | HCT 116 | C67(0.87); C184(1.02); C215(1.04); C180(1.09) | LDD0599 | [6] |
LDCM0283 | AC23 | HCT 116 | C180(0.92); C184(0.95); C67(0.96); C215(1.07) | LDD0600 | [6] |
LDCM0284 | AC24 | HCT 116 | C215(1.02); C67(1.03); C180(1.06); C184(1.12) | LDD0601 | [6] |
LDCM0285 | AC25 | HCT 116 | C180(0.82); C184(0.84); C215(0.97); C67(0.99) | LDD0602 | [6] |
LDCM0286 | AC26 | HCT 116 | C180(0.73); C184(0.95); C67(0.99); C215(1.05) | LDD0603 | [6] |
LDCM0287 | AC27 | HCT 116 | C180(0.70); C184(0.80); C67(0.90); C215(0.94) | LDD0604 | [6] |
LDCM0288 | AC28 | HCT 116 | C180(0.66); C184(0.95); C67(0.99); C215(1.08) | LDD0605 | [6] |
LDCM0289 | AC29 | HCT 116 | C180(0.72); C184(0.96); C67(1.10); C215(1.38) | LDD0606 | [6] |
LDCM0290 | AC3 | HCT 116 | C180(0.89); C184(0.95); C67(1.08); C215(1.13) | LDD0607 | [6] |
LDCM0291 | AC30 | HCT 116 | C180(0.63); C184(0.87); C67(0.97); C215(1.34) | LDD0608 | [6] |
LDCM0292 | AC31 | HCT 116 | C180(0.63); C184(0.89); C67(0.95); C215(1.03) | LDD0609 | [6] |
LDCM0293 | AC32 | HCT 116 | C180(0.50); C67(0.98); C184(0.99); C215(1.28) | LDD0610 | [6] |
LDCM0294 | AC33 | HCT 116 | C180(0.56); C67(0.80); C184(0.88); C215(0.94) | LDD0611 | [6] |
LDCM0295 | AC34 | HCT 116 | C180(0.50); C184(0.79); C67(0.84); C215(1.02) | LDD0612 | [6] |
LDCM0296 | AC35 | HCT 116 | C215(0.76); C184(0.97); C67(0.98); C180(0.99) | LDD0613 | [6] |
LDCM0297 | AC36 | HCT 116 | C215(0.85); C184(0.98); C180(0.99); C67(1.14) | LDD0614 | [6] |
LDCM0298 | AC37 | HCT 116 | C215(0.82); C184(0.94); C180(0.98); C67(1.09) | LDD0615 | [6] |
LDCM0299 | AC38 | HCT 116 | C180(0.99); C184(1.02); C215(1.12); C67(1.15) | LDD0616 | [6] |
LDCM0300 | AC39 | HCT 116 | C180(0.87); C215(0.89); C184(0.92); C67(1.07) | LDD0617 | [6] |
LDCM0301 | AC4 | HCT 116 | C180(0.77); C184(0.78); C67(1.14); C215(1.19) | LDD0618 | [6] |
LDCM0302 | AC40 | HCT 116 | C180(0.77); C184(0.81); C67(0.95); C215(1.11) | LDD0619 | [6] |
LDCM0303 | AC41 | HCT 116 | C180(0.83); C184(0.94); C215(1.09); C67(1.29) | LDD0620 | [6] |
LDCM0304 | AC42 | HCT 116 | C180(0.78); C184(0.87); C67(0.98); C215(1.03) | LDD0621 | [6] |
LDCM0305 | AC43 | HCT 116 | C180(0.85); C67(0.98); C184(1.01); C215(1.22) | LDD0622 | [6] |
LDCM0306 | AC44 | HCT 116 | C180(0.79); C184(0.91); C67(0.95); C215(1.26) | LDD0623 | [6] |
LDCM0307 | AC45 | HCT 116 | C180(0.75); C184(0.80); C67(1.10); C215(1.20) | LDD0624 | [6] |
LDCM0308 | AC46 | HCT 116 | C180(1.06); C184(1.09); C215(1.29) | LDD0625 | [6] |
LDCM0309 | AC47 | HCT 116 | C184(0.93); C180(0.94); C215(1.26) | LDD0626 | [6] |
LDCM0310 | AC48 | HCT 116 | C184(1.09); C180(1.19); C215(1.30) | LDD0627 | [6] |
LDCM0311 | AC49 | HCT 116 | C180(0.79); C184(0.93); C215(1.75) | LDD0628 | [6] |
LDCM0312 | AC5 | HCT 116 | C180(0.76); C184(0.76); C67(1.02); C215(1.31) | LDD0629 | [6] |
LDCM0313 | AC50 | HCT 116 | C180(0.86); C184(0.97); C215(1.51) | LDD0630 | [6] |
LDCM0314 | AC51 | HCT 116 | C215(1.06); C184(1.37); C180(1.54) | LDD0631 | [6] |
LDCM0315 | AC52 | HCT 116 | C184(0.97); C180(1.00); C215(1.22) | LDD0632 | [6] |
LDCM0316 | AC53 | HCT 116 | C180(0.99); C184(1.01); C215(1.28) | LDD0633 | [6] |
LDCM0317 | AC54 | HCT 116 | C180(0.94); C184(0.95); C215(1.40) | LDD0634 | [6] |
LDCM0318 | AC55 | HCT 116 | C180(0.88); C184(0.91); C215(1.34) | LDD0635 | [6] |
LDCM0319 | AC56 | HCT 116 | C180(0.78); C184(0.88); C215(1.72) | LDD0636 | [6] |
LDCM0320 | AC57 | HCT 116 | C180(0.75); C184(0.92); C215(1.56) | LDD0637 | [6] |
LDCM0321 | AC58 | HCT 116 | C180(0.69); C184(0.95); C215(1.64) | LDD0638 | [6] |
LDCM0322 | AC59 | HCT 116 | C180(0.76); C184(0.89); C215(1.65) | LDD0639 | [6] |
LDCM0323 | AC6 | HCT 116 | C180(0.68); C184(0.78); C67(1.04); C215(1.24) | LDD0640 | [6] |
LDCM0324 | AC60 | HCT 116 | C180(0.72); C184(0.89); C215(1.52) | LDD0641 | [6] |
LDCM0325 | AC61 | HCT 116 | C180(0.80); C184(0.91); C215(1.40) | LDD0642 | [6] |
LDCM0326 | AC62 | HCT 116 | C180(0.72); C184(0.87); C215(1.83) | LDD0643 | [6] |
LDCM0327 | AC63 | HCT 116 | C180(0.77); C184(0.88); C215(1.45) | LDD0644 | [6] |
LDCM0328 | AC64 | HCT 116 | C180(0.75); C184(0.89); C215(1.73) | LDD0645 | [6] |
LDCM0329 | AC65 | HCT 116 | C180(0.68); C184(0.90); C215(1.95) | LDD0646 | [6] |
LDCM0330 | AC66 | HCT 116 | C180(0.76); C184(1.02); C215(1.82) | LDD0647 | [6] |
LDCM0331 | AC67 | HCT 116 | C180(0.58); C184(0.79); C215(2.38) | LDD0648 | [6] |
LDCM0332 | AC68 | HCT 116 | C180(0.90); C184(0.92); C215(1.18) | LDD0649 | [6] |
LDCM0333 | AC69 | HCT 116 | C180(0.88); C184(0.90); C215(1.23) | LDD0650 | [6] |
LDCM0334 | AC7 | HCT 116 | C180(0.86); C184(0.86); C67(0.94); C215(1.10) | LDD0651 | [6] |
LDCM0335 | AC70 | HCT 116 | C180(0.78); C184(0.83); C215(1.30) | LDD0652 | [6] |
LDCM0336 | AC71 | HCT 116 | C184(1.01); C180(1.05); C215(1.06) | LDD0653 | [6] |
LDCM0337 | AC72 | HCT 116 | C180(0.85); C184(0.94); C215(1.31) | LDD0654 | [6] |
LDCM0338 | AC73 | HCT 116 | C180(0.74); C184(0.91); C215(1.86) | LDD0655 | [6] |
LDCM0339 | AC74 | HCT 116 | C180(0.81); C184(0.87); C215(1.87) | LDD0656 | [6] |
LDCM0340 | AC75 | HCT 116 | C180(0.76); C184(0.91); C215(2.07) | LDD0657 | [6] |
LDCM0341 | AC76 | HCT 116 | C180(0.94); C184(0.95); C215(1.32) | LDD0658 | [6] |
LDCM0342 | AC77 | HCT 116 | C180(0.85); C184(0.96); C215(1.35) | LDD0659 | [6] |
LDCM0343 | AC78 | HCT 116 | C184(0.94); C180(0.97); C215(1.08) | LDD0660 | [6] |
LDCM0344 | AC79 | HCT 116 | C180(0.92); C184(0.96); C215(1.25) | LDD0661 | [6] |
LDCM0345 | AC8 | HCT 116 | C184(0.81); C180(0.83); C67(1.00); C215(1.21) | LDD0662 | [6] |
LDCM0346 | AC80 | HCT 116 | C184(0.93); C180(0.98); C215(1.12) | LDD0663 | [6] |
LDCM0347 | AC81 | HCT 116 | C180(0.97); C215(0.99); C184(1.00) | LDD0664 | [6] |
LDCM0348 | AC82 | HCT 116 | C180(0.84); C184(0.93); C215(2.01) | LDD0665 | [6] |
LDCM0349 | AC83 | HCT 116 | C180(0.41); C184(0.76); C67(1.09); C215(1.74) | LDD0666 | [6] |
LDCM0350 | AC84 | HCT 116 | C180(0.42); C184(0.73); C67(0.98); C215(1.47) | LDD0667 | [6] |
LDCM0351 | AC85 | HCT 116 | C180(0.49); C184(0.77); C67(1.06); C215(1.35) | LDD0668 | [6] |
LDCM0352 | AC86 | HCT 116 | C180(0.56); C184(0.79); C67(0.96); C215(1.29) | LDD0669 | [6] |
LDCM0353 | AC87 | HCT 116 | C180(0.74); C184(0.86); C215(1.03); C67(1.14) | LDD0670 | [6] |
LDCM0354 | AC88 | HCT 116 | C180(0.59); C184(0.80); C67(1.01); C215(1.19) | LDD0671 | [6] |
LDCM0355 | AC89 | HCT 116 | C180(0.53); C184(0.69); C67(1.15); C215(1.30) | LDD0672 | [6] |
LDCM0357 | AC90 | HCT 116 | C184(1.09); C215(1.14); C67(1.14); C180(1.35) | LDD0674 | [6] |
LDCM0358 | AC91 | HCT 116 | C180(0.57); C184(0.85); C67(1.01); C215(1.56) | LDD0675 | [6] |
LDCM0359 | AC92 | HCT 116 | C180(0.49); C184(0.66); C67(1.12); C215(1.45) | LDD0676 | [6] |
LDCM0360 | AC93 | HCT 116 | C180(0.55); C184(0.67); C215(1.17); C67(1.21) | LDD0677 | [6] |
LDCM0361 | AC94 | HCT 116 | C180(0.74); C184(0.82); C67(1.20); C215(1.25) | LDD0678 | [6] |
LDCM0362 | AC95 | HCT 116 | C180(0.73); C184(0.92); C67(1.13); C215(1.15) | LDD0679 | [6] |
LDCM0363 | AC96 | HCT 116 | C180(0.65); C184(0.77); C67(0.93); C215(1.26) | LDD0680 | [6] |
LDCM0364 | AC97 | HCT 116 | C180(0.44); C184(0.81); C67(1.13); C215(1.45) | LDD0681 | [6] |
LDCM0365 | AC98 | HCT 116 | C180(0.40); C184(0.71); C67(0.99); C215(1.73) | LDD0682 | [6] |
LDCM0366 | AC99 | HCT 116 | C180(0.59); C184(0.67); C67(0.83); C215(1.14) | LDD0683 | [6] |
LDCM0248 | AKOS034007472 | HCT 116 | C180(0.95); C184(0.93); C215(0.97); C67(0.96) | LDD0565 | [6] |
LDCM0356 | AKOS034007680 | HCT 116 | C184(0.83); C180(0.85); C215(1.03); C67(1.05) | LDD0673 | [6] |
LDCM0275 | AKOS034007705 | HCT 116 | C180(0.59); C184(0.75); C67(1.09); C215(1.66) | LDD0592 | [6] |
LDCM0156 | Aniline | NCI-H1299 | 11.78 | LDD0403 | [1] |
LDCM0020 | ARS-1620 | HCC44 | C215(0.99) | LDD0078 | [6] |
LDCM0498 | BS-3668 | MDA-MB-231 | C215(0.75) | LDD2091 | [4] |
LDCM0630 | CCW28-3 | 231MFP | C215(1.43) | LDD2214 | [21] |
LDCM0108 | Chloroacetamide | HeLa | C67(0.00); C215(0.00); H116(0.00) | LDD0222 | [14] |
LDCM0367 | CL1 | HCT 116 | C67(0.79); C215(0.87); C184(0.98); C180(1.18) | LDD0684 | [6] |
LDCM0368 | CL10 | HCT 116 | C180(0.65); C184(1.02); C67(1.06); C215(1.18) | LDD0685 | [6] |
LDCM0369 | CL100 | HCT 116 | C180(0.60); C184(0.77); C67(1.03); C215(1.24) | LDD0686 | [6] |
LDCM0370 | CL101 | HCT 116 | C180(0.78); C184(0.88); C215(1.17); C67(1.25) | LDD0687 | [6] |
LDCM0371 | CL102 | HCT 116 | C180(0.90); C215(0.98); C184(1.03); C67(1.17) | LDD0688 | [6] |
LDCM0372 | CL103 | HCT 116 | C215(0.91); C180(1.01); C184(1.06); C67(1.11) | LDD0689 | [6] |
LDCM0373 | CL104 | HCT 116 | C180(0.90); C184(1.07); C67(1.10); C215(1.12) | LDD0690 | [6] |
LDCM0374 | CL105 | HCT 116 | C180(0.81); C184(0.84); C67(0.84); C215(1.28) | LDD0691 | [6] |
LDCM0375 | CL106 | HCT 116 | C67(0.75); C184(0.78); C180(0.86); C215(1.63) | LDD0692 | [6] |
LDCM0376 | CL107 | HCT 116 | C67(0.83); C184(0.87); C180(0.91); C215(1.56) | LDD0693 | [6] |
LDCM0377 | CL108 | HCT 116 | C180(0.83); C184(0.83); C67(0.84); C215(1.73) | LDD0694 | [6] |
LDCM0378 | CL109 | HCT 116 | C67(0.78); C180(0.87); C184(0.91); C215(1.16) | LDD0695 | [6] |
LDCM0379 | CL11 | HCT 116 | C180(0.62); C184(0.91); C67(0.99); C215(1.17) | LDD0696 | [6] |
LDCM0380 | CL110 | HCT 116 | C67(0.78); C180(0.92); C184(0.95); C215(1.29) | LDD0697 | [6] |
LDCM0381 | CL111 | HCT 116 | C67(0.85); C180(0.87); C184(1.00); C215(1.18) | LDD0698 | [6] |
LDCM0382 | CL112 | HCT 116 | C215(0.87); C184(0.97); C180(0.98); C67(1.06) | LDD0699 | [6] |
LDCM0383 | CL113 | HCT 116 | C180(0.56); C184(0.92); C67(0.97); C215(1.16) | LDD0700 | [6] |
LDCM0384 | CL114 | HCT 116 | C180(0.87); C67(0.90); C184(1.08); C215(1.18) | LDD0701 | [6] |
LDCM0385 | CL115 | HCT 116 | C180(0.69); C184(0.90); C67(0.97); C215(1.16) | LDD0702 | [6] |
LDCM0386 | CL116 | HCT 116 | C180(0.68); C184(0.88); C67(0.93); C215(0.98) | LDD0703 | [6] |
LDCM0387 | CL117 | HCT 116 | C180(0.70); C184(0.79); C67(0.87); C215(1.25) | LDD0704 | [6] |
LDCM0388 | CL118 | HCT 116 | C180(0.89); C184(0.92); C215(1.15); C67(1.22) | LDD0705 | [6] |
LDCM0389 | CL119 | HCT 116 | C180(0.89); C184(0.97); C215(0.98); C67(1.14) | LDD0706 | [6] |
LDCM0390 | CL12 | HCT 116 | C180(0.60); C184(1.00); C215(1.46); C67(1.67) | LDD0707 | [6] |
LDCM0391 | CL120 | HCT 116 | C180(0.93); C215(0.93); C184(0.97); C67(0.97) | LDD0708 | [6] |
LDCM0392 | CL121 | HCT 116 | C215(0.81); C184(1.23); C180(1.42) | LDD0709 | [6] |
LDCM0393 | CL122 | HCT 116 | C180(0.82); C184(0.96); C215(1.36) | LDD0710 | [6] |
LDCM0394 | CL123 | HCT 116 | C180(0.92); C184(0.94); C215(1.65) | LDD0711 | [6] |
LDCM0395 | CL124 | HCT 116 | C180(0.85); C184(0.91); C215(1.47) | LDD0712 | [6] |
LDCM0396 | CL125 | HCT 116 | C184(1.10); C180(1.10); C215(1.15) | LDD0713 | [6] |
LDCM0397 | CL126 | HCT 116 | C180(0.85); C184(1.05); C215(1.20) | LDD0714 | [6] |
LDCM0398 | CL127 | HCT 116 | C180(0.85); C184(1.00); C215(1.19) | LDD0715 | [6] |
LDCM0399 | CL128 | HCT 116 | C180(0.75); C184(0.81); C215(1.51) | LDD0716 | [6] |
LDCM0400 | CL13 | HCT 116 | C180(0.67); C184(0.89); C215(1.06); C67(1.25) | LDD0717 | [6] |
LDCM0401 | CL14 | HCT 116 | C180(0.91); C184(0.97); C215(1.08); C67(1.33) | LDD0718 | [6] |
LDCM0402 | CL15 | HCT 116 | C180(0.63); C184(0.91); C67(1.15); C215(1.17) | LDD0719 | [6] |
LDCM0403 | CL16 | HCT 116 | C180(0.72); C67(0.81); C184(0.99); C215(1.05) | LDD0720 | [6] |
LDCM0404 | CL17 | HCT 116 | C180(0.51); C67(0.75); C184(0.90); C215(0.90) | LDD0721 | [6] |
LDCM0405 | CL18 | HCT 116 | C180(0.44); C67(0.76); C184(0.96); C215(1.03) | LDD0722 | [6] |
LDCM0406 | CL19 | HCT 116 | C180(0.41); C67(0.72); C215(1.00); C184(1.02) | LDD0723 | [6] |
LDCM0407 | CL2 | HCT 116 | C67(0.88); C215(0.93); C184(1.03); C180(1.28) | LDD0724 | [6] |
LDCM0408 | CL20 | HCT 116 | C180(0.36); C67(0.90); C184(1.06); C215(1.06) | LDD0725 | [6] |
LDCM0409 | CL21 | HCT 116 | C180(0.41); C67(0.62); C184(0.99); C215(1.51) | LDD0726 | [6] |
LDCM0410 | CL22 | HCT 116 | C180(0.36); C67(0.70); C184(1.38); C215(1.74) | LDD0727 | [6] |
LDCM0411 | CL23 | HCT 116 | C180(0.39); C67(0.77); C184(0.89); C215(1.04) | LDD0728 | [6] |
LDCM0412 | CL24 | HCT 116 | C180(0.33); C67(0.76); C184(1.06); C215(1.23) | LDD0729 | [6] |
LDCM0413 | CL25 | HCT 116 | C180(0.41); C184(0.99); C215(1.09); C67(0.69) | LDD0730 | [6] |
LDCM0414 | CL26 | HCT 116 | C180(0.45); C184(1.03); C215(1.11); C67(0.76) | LDD0731 | [6] |
LDCM0415 | CL27 | HCT 116 | C180(0.43); C184(0.95); C215(1.03); C67(0.74) | LDD0732 | [6] |
LDCM0416 | CL28 | HCT 116 | C180(0.41); C184(1.09); C215(1.14); C67(0.65) | LDD0733 | [6] |
LDCM0417 | CL29 | HCT 116 | C180(0.38); C184(0.94); C215(1.11); C67(0.80) | LDD0734 | [6] |
LDCM0418 | CL3 | HCT 116 | C180(1.01); C184(0.97); C215(0.86); C67(1.23) | LDD0735 | [6] |
LDCM0419 | CL30 | HCT 116 | C180(0.50); C184(0.87); C215(0.98); C67(0.79) | LDD0736 | [6] |
LDCM0420 | CL31 | HCT 116 | C180(0.66); C184(0.92); C215(1.15); C67(1.01) | LDD0737 | [6] |
LDCM0421 | CL32 | HCT 116 | C180(0.61); C184(0.96); C215(1.15); C67(1.00) | LDD0738 | [6] |
LDCM0422 | CL33 | HCT 116 | C180(0.63); C184(0.94); C215(1.13); C67(0.80) | LDD0739 | [6] |
LDCM0423 | CL34 | HCT 116 | C180(0.63); C184(1.04); C215(1.46); C67(0.90) | LDD0740 | [6] |
LDCM0424 | CL35 | HCT 116 | C180(0.57); C184(1.01); C215(1.34); C67(1.08) | LDD0741 | [6] |
LDCM0425 | CL36 | HCT 116 | C180(0.70); C184(1.02); C215(1.22); C67(1.00) | LDD0742 | [6] |
LDCM0426 | CL37 | HCT 116 | C180(0.63); C184(1.10); C215(1.40); C67(1.10) | LDD0743 | [6] |
LDCM0428 | CL39 | HCT 116 | C180(0.70); C184(1.03); C215(1.38); C67(1.10) | LDD0745 | [6] |
LDCM0429 | CL4 | HCT 116 | C180(0.89); C184(0.99); C215(0.93); C67(1.05) | LDD0746 | [6] |
LDCM0430 | CL40 | HCT 116 | C180(0.66); C184(1.02); C215(1.27); C67(0.89) | LDD0747 | [6] |
LDCM0431 | CL41 | HCT 116 | C180(0.68); C184(1.03); C215(1.24); C67(0.99) | LDD0748 | [6] |
LDCM0432 | CL42 | HCT 116 | C180(0.68); C184(1.15); C215(1.83); C67(0.93) | LDD0749 | [6] |
LDCM0433 | CL43 | HCT 116 | C180(0.62); C184(1.07); C215(1.50); C67(1.02) | LDD0750 | [6] |
LDCM0434 | CL44 | HCT 116 | C180(0.69); C184(0.98); C215(1.20); C67(1.08) | LDD0751 | [6] |
LDCM0435 | CL45 | HCT 116 | C180(0.65); C184(0.95); C215(1.48); C67(1.03) | LDD0752 | [6] |
LDCM0436 | CL46 | HCT 116 | C180(1.46); C184(0.99); C215(0.96) | LDD0753 | [6] |
LDCM0437 | CL47 | HCT 116 | C180(1.85); C184(1.29); C215(0.92) | LDD0754 | [6] |
LDCM0438 | CL48 | HCT 116 | C180(1.62); C184(1.10); C215(0.91) | LDD0755 | [6] |
LDCM0439 | CL49 | HCT 116 | C180(1.29); C184(1.13); C215(0.93) | LDD0756 | [6] |
LDCM0440 | CL5 | HCT 116 | C180(0.86); C184(0.95); C215(0.90); C67(1.08) | LDD0757 | [6] |
LDCM0441 | CL50 | HCT 116 | C180(1.28); C184(1.12); C215(0.88) | LDD0758 | [6] |
LDCM0442 | CL51 | HCT 116 | C180(1.41); C184(0.99); C215(0.95) | LDD0759 | [6] |
LDCM0443 | CL52 | HCT 116 | C180(1.38); C184(1.24); C215(0.97) | LDD0760 | [6] |
LDCM0444 | CL53 | HCT 116 | C180(1.52); C184(1.18); C215(0.83) | LDD0761 | [6] |
LDCM0445 | CL54 | HCT 116 | C180(2.02); C184(1.24); C215(0.92) | LDD0762 | [6] |
LDCM0446 | CL55 | HCT 116 | C180(1.82); C184(1.19); C215(0.87) | LDD0763 | [6] |
LDCM0447 | CL56 | HCT 116 | C180(1.14); C184(0.98); C215(1.01) | LDD0764 | [6] |
LDCM0448 | CL57 | HCT 116 | C180(1.39); C184(1.17); C215(0.83) | LDD0765 | [6] |
LDCM0449 | CL58 | HCT 116 | C180(1.26); C184(1.24); C215(0.90) | LDD0766 | [6] |
LDCM0450 | CL59 | HCT 116 | C180(1.23); C184(0.95); C215(0.90) | LDD0767 | [6] |
LDCM0451 | CL6 | HCT 116 | C180(0.72); C184(0.88); C215(1.11); C67(0.99) | LDD0768 | [6] |
LDCM0452 | CL60 | HCT 116 | C180(1.26); C184(1.14); C215(0.90) | LDD0769 | [6] |
LDCM0453 | CL61 | HCT 116 | C180(1.19); C184(1.03); C215(1.26); C67(1.22) | LDD0770 | [6] |
LDCM0454 | CL62 | HCT 116 | C180(0.93); C184(0.85); C215(1.22); C67(1.15) | LDD0771 | [6] |
LDCM0455 | CL63 | HCT 116 | C180(0.77); C184(0.75); C215(1.27); C67(0.96) | LDD0772 | [6] |
LDCM0456 | CL64 | HCT 116 | C180(0.80); C184(0.77); C215(1.45); C67(0.85) | LDD0773 | [6] |
LDCM0457 | CL65 | HCT 116 | C180(0.90); C184(0.84); C215(1.24); C67(1.03) | LDD0774 | [6] |
LDCM0458 | CL66 | HCT 116 | C180(0.64); C184(0.69); C215(1.81); C67(1.06) | LDD0775 | [6] |
LDCM0459 | CL67 | HCT 116 | C180(0.70); C184(0.65); C215(1.45); C67(0.91) | LDD0776 | [6] |
LDCM0460 | CL68 | HCT 116 | C180(1.13); C184(0.92); C215(1.41); C67(0.98) | LDD0777 | [6] |
LDCM0461 | CL69 | HCT 116 | C180(1.17); C184(1.02); C215(1.19); C67(1.23) | LDD0778 | [6] |
LDCM0462 | CL7 | HCT 116 | C180(0.66); C184(0.86); C215(1.32); C67(1.10) | LDD0779 | [6] |
LDCM0463 | CL70 | HCT 116 | C180(0.94); C184(0.88); C215(1.28); C67(1.17) | LDD0780 | [6] |
LDCM0464 | CL71 | HCT 116 | C180(0.80); C184(0.74); C215(1.31); C67(1.14) | LDD0781 | [6] |
LDCM0465 | CL72 | HCT 116 | C180(1.22); C184(1.05); C215(1.17); C67(0.99) | LDD0782 | [6] |
LDCM0466 | CL73 | HCT 116 | C180(0.83); C184(0.71); C215(1.34); C67(0.98) | LDD0783 | [6] |
LDCM0467 | CL74 | HCT 116 | C180(0.79); C184(0.80); C215(1.31); C67(1.04) | LDD0784 | [6] |
LDCM0469 | CL76 | HCT 116 | C180(0.70); C184(0.84); C215(1.11) | LDD0786 | [6] |
LDCM0470 | CL77 | HCT 116 | C180(0.69); C184(0.81); C215(1.04) | LDD0787 | [6] |
LDCM0471 | CL78 | HCT 116 | C180(0.63); C184(0.82); C215(1.15) | LDD0788 | [6] |
LDCM0472 | CL79 | HCT 116 | C180(0.67); C184(0.87); C215(1.48) | LDD0789 | [6] |
LDCM0473 | CL8 | HCT 116 | C180(0.62); C184(1.01); C215(1.55); C67(0.72) | LDD0790 | [6] |
LDCM0474 | CL80 | HCT 116 | C180(0.88); C184(0.94); C215(1.08) | LDD0791 | [6] |
LDCM0475 | CL81 | HCT 116 | C180(0.74); C184(0.87); C215(1.26) | LDD0792 | [6] |
LDCM0476 | CL82 | HCT 116 | C180(0.75); C184(0.91); C215(1.74) | LDD0793 | [6] |
LDCM0477 | CL83 | HCT 116 | C180(0.65); C184(0.82); C215(1.72) | LDD0794 | [6] |
LDCM0478 | CL84 | HCT 116 | C180(0.56); C184(0.81); C215(2.09) | LDD0795 | [6] |
LDCM0479 | CL85 | HCT 116 | C180(0.70); C184(0.85); C215(1.34) | LDD0796 | [6] |
LDCM0480 | CL86 | HCT 116 | C180(0.88); C184(0.92); C215(1.15) | LDD0797 | [6] |
LDCM0481 | CL87 | HCT 116 | C180(0.83); C184(0.84); C215(1.32) | LDD0798 | [6] |
LDCM0482 | CL88 | HCT 116 | C180(0.77); C184(0.78); C215(1.54) | LDD0799 | [6] |
LDCM0483 | CL89 | HCT 116 | C180(0.65); C184(0.82); C215(2.43) | LDD0800 | [6] |
LDCM0484 | CL9 | HCT 116 | C180(0.71); C184(0.92); C215(1.06); C67(1.05) | LDD0801 | [6] |
LDCM0485 | CL90 | HCT 116 | C180(1.01); C184(1.10); C215(1.09) | LDD0802 | [6] |
LDCM0486 | CL91 | HCT 116 | C180(0.83); C184(1.08); C215(1.14); C67(1.07) | LDD0803 | [6] |
LDCM0487 | CL92 | HCT 116 | C180(0.88); C184(1.02); C215(1.12); C67(0.85) | LDD0804 | [6] |
LDCM0488 | CL93 | HCT 116 | C180(0.98); C184(0.98); C215(1.01); C67(0.97) | LDD0805 | [6] |
LDCM0489 | CL94 | HCT 116 | C180(0.68); C184(0.87); C215(1.23); C67(1.03) | LDD0806 | [6] |
LDCM0490 | CL95 | HCT 116 | C180(0.68); C184(0.86); C215(1.25); C67(0.96) | LDD0807 | [6] |
LDCM0491 | CL96 | HCT 116 | C180(0.87); C184(1.01); C215(1.12); C67(0.81) | LDD0808 | [6] |
LDCM0492 | CL97 | HCT 116 | C180(0.68); C184(0.96); C215(1.14); C67(1.03) | LDD0809 | [6] |
LDCM0493 | CL98 | HCT 116 | C180(0.67); C184(0.81); C215(1.20); C67(1.03) | LDD0810 | [6] |
LDCM0494 | CL99 | HCT 116 | C180(0.84); C184(0.85); C215(1.15); C67(0.98) | LDD0811 | [6] |
LDCM0634 | CY-0357 | Hep-G2 | C215(0.37) | LDD2228 | [9] |
LDCM0495 | E2913 | HEK-293T | C67(0.92); C215(0.89); C257(0.70); C184(0.95) | LDD1698 | [22] |
LDCM0213 | Electrophilic fragment 2 | MDA-MB-231 | C215(1.37); C67(1.26) | LDD1702 | [4] |
LDCM0625 | F8 | Ramos | C215(1.32) | LDD2187 | [23] |
LDCM0572 | Fragment10 | Ramos | C215(0.67) | LDD2189 | [23] |
LDCM0573 | Fragment11 | Ramos | C215(0.18) | LDD2190 | [23] |
LDCM0574 | Fragment12 | Ramos | C215(0.92) | LDD2191 | [23] |
LDCM0575 | Fragment13 | Ramos | C215(1.01) | LDD2192 | [23] |
LDCM0576 | Fragment14 | Ramos | C215(0.79) | LDD2193 | [23] |
LDCM0579 | Fragment20 | Ramos | C215(1.15) | LDD2194 | [23] |
LDCM0580 | Fragment21 | Ramos | C215(0.90) | LDD2195 | [23] |
LDCM0582 | Fragment23 | Ramos | C215(1.05) | LDD2196 | [23] |
LDCM0578 | Fragment27 | Ramos | C215(0.86) | LDD2197 | [23] |
LDCM0586 | Fragment28 | Ramos | C215(0.87) | LDD2198 | [23] |
LDCM0588 | Fragment30 | Ramos | C215(0.99) | LDD2199 | [23] |
LDCM0589 | Fragment31 | Ramos | C215(0.91) | LDD2200 | [23] |
LDCM0590 | Fragment32 | Ramos | C215(1.30) | LDD2201 | [23] |
LDCM0468 | Fragment33 | HCT 116 | C180(1.05); C184(0.90); C215(1.27); C67(0.95) | LDD0785 | [6] |
LDCM0596 | Fragment38 | Ramos | C215(0.77) | LDD2203 | [23] |
LDCM0566 | Fragment4 | Ramos | C215(0.75) | LDD2184 | [23] |
LDCM0427 | Fragment51 | HCT 116 | C180(0.60); C184(1.15); C215(1.76); C67(1.04) | LDD0744 | [6] |
LDCM0610 | Fragment52 | Ramos | C215(1.00) | LDD2204 | [23] |
LDCM0614 | Fragment56 | Ramos | C215(0.96) | LDD2205 | [23] |
LDCM0569 | Fragment7 | Ramos | C215(0.73) | LDD2186 | [23] |
LDCM0571 | Fragment9 | Ramos | C215(2.22) | LDD2188 | [23] |
LDCM0107 | IAA | HeLa | H116(0.00); C67(0.00) | LDD0221 | [14] |
LDCM0022 | KB02 | HCT 116 | C184(1.42); C215(2.38) | LDD0080 | [6] |
LDCM0023 | KB03 | HCT 116 | C184(1.53); C215(1.50) | LDD0081 | [6] |
LDCM0024 | KB05 | HCT 116 | C184(1.22); C215(1.14) | LDD0082 | [6] |
LDCM0528 | N-(4-bromophenyl)-2-cyano-N-phenylacetamide | MDA-MB-231 | C67(0.75) | LDD2121 | [4] |
LDCM0109 | NEM | HeLa | N.A. | LDD0224 | [14] |
LDCM0497 | Nucleophilic fragment 11b | MDA-MB-231 | C67(1.29) | LDD2090 | [4] |
LDCM0500 | Nucleophilic fragment 13a | MDA-MB-231 | C67(0.95) | LDD2093 | [4] |
LDCM0504 | Nucleophilic fragment 15a | MDA-MB-231 | C67(0.73) | LDD2097 | [4] |
LDCM0506 | Nucleophilic fragment 16a | MDA-MB-231 | C67(1.00) | LDD2099 | [4] |
LDCM0507 | Nucleophilic fragment 16b | MDA-MB-231 | C67(1.29) | LDD2100 | [4] |
LDCM0508 | Nucleophilic fragment 17a | MDA-MB-231 | C67(0.93) | LDD2101 | [4] |
LDCM0511 | Nucleophilic fragment 18b | MDA-MB-231 | C67(0.40) | LDD2104 | [4] |
LDCM0513 | Nucleophilic fragment 19b | MDA-MB-231 | C67(0.35) | LDD2106 | [4] |
LDCM0514 | Nucleophilic fragment 20a | MDA-MB-231 | C67(0.90) | LDD2107 | [4] |
LDCM0515 | Nucleophilic fragment 20b | MDA-MB-231 | C67(0.32) | LDD2108 | [4] |
LDCM0518 | Nucleophilic fragment 22a | MDA-MB-231 | C67(0.96) | LDD2111 | [4] |
LDCM0521 | Nucleophilic fragment 23b | MDA-MB-231 | C215(0.77) | LDD2114 | [4] |
LDCM0526 | Nucleophilic fragment 26a | MDA-MB-231 | C67(1.65) | LDD2119 | [4] |
LDCM0527 | Nucleophilic fragment 26b | MDA-MB-231 | C67(0.58) | LDD2120 | [4] |
LDCM0530 | Nucleophilic fragment 28a | MDA-MB-231 | C67(0.71) | LDD2123 | [4] |
LDCM0532 | Nucleophilic fragment 29a | MDA-MB-231 | C67(0.66) | LDD2125 | [4] |
LDCM0534 | Nucleophilic fragment 30a | MDA-MB-231 | C67(0.73) | LDD2127 | [4] |
LDCM0535 | Nucleophilic fragment 30b | MDA-MB-231 | C67(0.50) | LDD2128 | [4] |
LDCM0536 | Nucleophilic fragment 31 | MDA-MB-231 | C67(1.04) | LDD2129 | [4] |
LDCM0541 | Nucleophilic fragment 36 | MDA-MB-231 | C67(0.53) | LDD2134 | [4] |
LDCM0542 | Nucleophilic fragment 37 | MDA-MB-231 | C67(1.12) | LDD2135 | [4] |
LDCM0543 | Nucleophilic fragment 38 | MDA-MB-231 | C67(1.11) | LDD2136 | [4] |
LDCM0544 | Nucleophilic fragment 39 | MDA-MB-231 | C67(0.69) | LDD2137 | [4] |
LDCM0211 | Nucleophilic fragment 3b | MDA-MB-231 | C67(2.02) | LDD1700 | [4] |
LDCM0546 | Nucleophilic fragment 40 | MDA-MB-231 | C67(0.66) | LDD2140 | [4] |
LDCM0547 | Nucleophilic fragment 41 | MDA-MB-231 | C215(0.78) | LDD2141 | [4] |
LDCM0549 | Nucleophilic fragment 43 | MDA-MB-231 | C67(0.28) | LDD2143 | [4] |
LDCM0550 | Nucleophilic fragment 5a | MDA-MB-231 | C67(1.66) | LDD2144 | [4] |
LDCM0552 | Nucleophilic fragment 6a | MDA-MB-231 | C67(0.77) | LDD2146 | [4] |
LDCM0553 | Nucleophilic fragment 6b | MDA-MB-231 | C67(0.83) | LDD2147 | [4] |
LDCM0554 | Nucleophilic fragment 7a | MDA-MB-231 | C67(0.44) | LDD2148 | [4] |
LDCM0556 | Nucleophilic fragment 8a | MDA-MB-231 | C215(0.58) | LDD2150 | [4] |
LDCM0627 | NUDT7-COV-1 | HEK-293T | C215(1.26); C184(0.38) | LDD2206 | [24] |
LDCM0628 | OTUB2-COV-1 | HEK-293T | C184(0.72); C215(0.47) | LDD2207 | [24] |
LDCM0131 | RA190 | MM1.R | C215(1.18); C184(1.08) | LDD0304 | [25] |
LDCM0021 | THZ1 | HCT 116 | C184(0.92) | LDD2173 | [6] |
LDCM0112 | W16 | Hep-G2 | C215(0.60) | LDD0239 | [15] |
LDCM0113 | W17 | Hep-G2 | C215(7.39) | LDD0240 | [15] |
The Interaction Atlas With This Target
The Protein(s) Related To This Target
Enzyme
Other
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
Exosome complex component RRP4 (EXOSC2) | RRP4 family | Q13868 | |||
Pre-rRNA-processing protein TSR2 homolog (TSR2) | TSR2 family | Q969E8 |
References