Details of the Probe

General Information of Probe

Probe ID
LDPC0453
Probe Name
C219
Synonyms
Z4282860711
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 323.4
Lipid-water partition coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C17H23F2N3O
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[(8,8-difluoro-4-bicyclo[5.1.0]octanyl)methyl]propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NCC2CCC3C(C3(F)F)CC2
InChI
InChI=1S/C17H23F2N3O/c1-2-3-9-16(21-22-16)10-8-15(23)20-11-12-4-6-13-14(7-5-12)17(13,18)19/h1,12-14H,3-11H2,(H,20,23)
InChIKey
CBIOGZOZXBZTKO-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

113 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 7.46  LDD1893 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 5.78  LDD1893 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 9.19  LDD1893 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 11.79  LDD1893 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 6.59  LDD1893 
Acid ceramidase (ASAH1) LDTP05905 11.55  LDD1893 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 8.63  LDD1893 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 4.99  LDD1893 
ADP-dependent glucokinase (ADPGK) LDTP11127 9.13  LDD1893 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 9.45  LDD1893 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 6.87  LDD1893 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 8.40  LDD1893 
Alpha-galactosidase A (GLA) LDTP02141 5.24  LDD1893 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 5.78  LDD1893 
Antigen peptide transporter 1 (TAP1) LDTP05408 14.72  LDD1893 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 6.63  LDD1893 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 9.45  LDD1893 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 26.72  LDD1893 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 7.01  LDD1893 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 6.32  LDD1893 
Beta-galactosidase (GLB1) LDTP02837 16.56  LDD1893 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 9.51  LDD1893 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 8.69  LDD1893 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 6.54  LDD1893 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 6.92  LDD1893 
Cartilage-associated protein (CRTAP) LDTP01300 8.51  LDD1893 
Catechol O-methyltransferase (COMT) LDTP03145 5.24  LDD1893 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 5.66  LDD1893 
Ceramide glucosyltransferase (UGCG) LDTP06617 11.63  LDD1893 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 5.43  LDD1893 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 9.32  LDD1893 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 7.46  LDD1893 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 7.26  LDD1893 
Cytochrome b5 type B (CYB5B) LDTP00697 23.10  LDD1893 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 7.06  LDD1893 
Delta(24)-sterol reductase (DHCR24) LDTP06375 9.99  LDD1893 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 4.92  LDD1893 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 6.36  LDD1893 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 6.36  LDD1893 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 7.78  LDD1893 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 7.06  LDD1893 
E3 ubiquitin-protein ligase RNF139 (RNF139) LDTP09556 6.68  LDD1893 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 9.85  LDD1893 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 5.74  LDD1893 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 9.65  LDD1893 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 6.82  LDD1893 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 6.96  LDD1893 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 4.96  LDD1893 
Heme oxygenase 1 (HMOX1) LDTP02359 7.73  LDD1893 
Heme oxygenase 2 (HMOX2) LDTP03540 19.29  LDD1893 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 9.13  LDD1893 
Holocytochrome c-type synthase (HCCS) LDTP04581 6.73  LDD1893 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 6.50  LDD1893 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 7.62  LDD1893 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 14.62  LDD1893 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 18.90  LDD1893 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 20.97  LDD1893 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 5.28  LDD1893 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 7.62  LDD1893 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 17.39  LDD1893 
Lysosomal acid phosphatase (ACP2) LDTP02539 6.77  LDD1893 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 7.31  LDD1893 
Lysosomal protective protein (CTSA) LDTP02505 15.03  LDD1893 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 6.96  LDD1893 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 15.89  LDD1893 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 26.72  LDD1893 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 16.80  LDD1893 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 4.99  LDD1893 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 7.16  LDD1893 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 7.46  LDD1893 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 7.52  LDD1893 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 5.98  LDD1893 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 8.82  LDD1893 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 5.66  LDD1893 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 13.18  LDD1893 
NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) LDTP01983 13.83  LDD1893 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 32.00  LDD1893 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 14.52  LDD1893 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 27.47  LDD1893 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 25.28  LDD1893 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 9.99  LDD1893 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 5.03  LDD1893 
Phospholipase A2 group XV (PLA2G15) LDTP09088 8.51  LDD1893 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 5.90  LDD1893 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 10.56  LDD1893 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 18.90  LDD1893 
Presequence protease, mitochondrial (PITRM1) LDTP07003 5.21  LDD1893 
Prostaglandin reductase 3 (PTGR3) LDTP15422 20.39  LDD1893 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 13.45  LDD1893 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 9.85  LDD1893 
Protein O-mannosyl-transferase TMTC3 (TMTC3) LDTP07868 7.16  LDD1893 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 7.01  LDD1893 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 6.73  LDD1893 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 6.54  LDD1893 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 16.34  LDD1893 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 9.85  LDD1893 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 5.62  LDD1893 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 5.66  LDD1893 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 7.01  LDD1893 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 10.48  LDD1893 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 8.17  LDD1893 
Squalene monooxygenase (SQLE) LDTP06142 6.23  LDD1893 
Stearoyl-CoA desaturase (SCD) LDTP00344 4.92  LDD1893 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 5.28  LDD1893 
Thimet oligopeptidase (THOP1) LDTP04542 10.70  LDD1893 
Thioredoxin-like protein 1 (TXNL1) LDTP00758 9.71  LDD1893 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 5.21  LDD1893 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 9.65  LDD1893 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 6.11  LDD1893 
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) LDTP11867 5.03  LDD1893 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 7.01  LDD1893 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 14.42  LDD1893 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 20.53  LDD1893 
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⏷ Show the Full List of 113 Enzyme
87 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 6.36  LDD1893 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 5.46  LDD1893 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 6.36  LDD1893 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 5.10  LDD1893 
Anoctamin-10 (ANO10) LDTP12704 5.28  LDD1893 
Anoctamin-6 (ANO6) LDTP06855 6.41  LDD1893 
ATP synthase subunit a (MT-ATP6) LDTP01804 12.55  LDD1893 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 18.13  LDD1893 
BOS complex subunit NCLN (NCLN) LDTP10036 17.51  LDD1893 
BRI3-binding protein (BRI3BP) LDTP15648 18.38  LDD1893 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 5.94  LDD1893 
CMP-sialic acid transporter (SLC35A1) LDTP05116 29.45  LDD1893 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 14.42  LDD1893 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 29.04  LDD1893 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 5.24  LDD1893 
Derlin-1 (DERL1) LDTP11245 5.74  LDD1893 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 23.26  LDD1893 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 6.06  LDD1893 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 5.35  LDD1893 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 5.50  LDD1893 
Integral membrane protein 2C (ITM2C) LDTP12451 5.74  LDD1893 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 6.28  LDD1893 
Lysosome membrane protein 2 (SCARB2) LDTP06034 18.64  LDD1893 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 12.73  LDD1893 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 10.85  LDD1893 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 5.17  LDD1893 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 10.13  LDD1893 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 8.69  LDD1893 
Metaxin-1 (MTX1) LDTP05900 21.11  LDD1893 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 5.90  LDD1893 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 5.82  LDD1893 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 10.78  LDD1893 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 64.00  LDD1893 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 56.10  LDD1893 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 5.39  LDD1893 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 11.16  LDD1893 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 6.45  LDD1893 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 8.88  LDD1893 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 13.00  LDD1893 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 4.99  LDD1893 
Mpv17-like protein 2 (MPV17L2) LDTP14952 10.34  LDD1893 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 10.85  LDD1893 
Nucleoporin NDC1 (NDC1) LDTP11213 10.63  LDD1893 
Nucleoporin Nup37 (NUP37) LDTP09203 6.23  LDD1893 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 6.15  LDD1893 
Pericentriolar material 1 protein (PCM1) LDTP06331 5.28  LDD1893 
Prosaposin (PSAP) LDTP02215 8.28  LDD1893 
Protein GPR107 (GPR107) LDTP07236 18.90  LDD1893 
Protein RER1 (RER1) LDTP00590 5.35  LDD1893 
Protein tweety homolog 3 (TTYH3) LDTP11615 33.13  LDD1893 
Protein YIPF3 (YIPF3) LDTP11626 6.11  LDD1893 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 9.45  LDD1893 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 6.68  LDD1893 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 12.73  LDD1893 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 7.16  LDD1893 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 8.11  LDD1893 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 14.52  LDD1893 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 5.43  LDD1893 
Sideroflexin-4 (SFXN4) LDTP07531 12.04  LDD1893 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 10.13  LDD1893 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 8.40  LDD1893 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 8.34  LDD1893 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 5.98  LDD1893 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 5.90  LDD1893 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 11.79  LDD1893 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 20.53  LDD1893 
Sugar transporter SWEET1 (SLC50A1) LDTP11136 15.24  LDD1893 
Surfeit locus protein 4 (SURF4) LDTP00592 8.40  LDD1893 
Tetraspanin-10 (TSPAN10) LDTP15967 13.74  LDD1893 
Tetraspanin-3 (TSPAN3) LDTP16813 29.24  LDD1893 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 16.34  LDD1893 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 9.38  LDD1893 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 5.03  LDD1893 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 14.32  LDD1893 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 6.82  LDD1893 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 8.75  LDD1893 
Transmembrane protein 126A (TMEM126A) LDTP15948 14.22  LDD1893 
Transmembrane protein 160 (TMEM160) LDTP20002 8.88  LDD1893 
Transmembrane protein 199 (TMEM199) LDTP08881 46.85  LDD1893 
Transmembrane protein 59 (TMEM59) LDTP11406 6.68  LDD1893 
Transmembrane protein 87A (TMEM87A) LDTP15481 18.00  LDD1893 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 5.86  LDD1893 
Vang-like protein 1 (VANGL1) LDTP09288 6.50  LDD1893 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 22.78  LDD1893 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 16.80  LDD1893 
Wolframin (WFS1) LDTP01380 5.54  LDD1893 
Zinc transporter 6 (SLC30A6) LDTP07490 14.22  LDD1893 
------------------------------------------------------------------------------------
⏷ Show the Full List of 87 Transporter and channel
2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 5.21  LDD1893 
Leukocyte surface antigen CD47 (CD47) LDTP05572 7.26  LDD1893 
------------------------------------------------------------------------------------
65 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 13.27  LDD1893 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 8.28  LDD1893 
Apolipoprotein L2 (APOL2) LDTP11076 10.34  LDD1893 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 7.01  LDD1893 
Centrin-2 (CETN2) LDTP03926 5.86  LDD1893 
Clustered mitochondria protein homolog (CLUH) LDTP14486 12.64  LDD1893 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 15.89  LDD1893 
DDB1- and CUL4-associated factor 7 (DCAF7) LDTP04947 7.46  LDD1893 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 16.11  LDD1893 
Dynactin subunit 3 (DCTN3) LDTP01359 5.06  LDD1893 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 9.85  LDD1893 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 6.87  LDD1893 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 36.00  LDD1893 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 26.91  LDD1893 
Eukaryotic translation initiation factor 4E (EIF4E) LDTP02156 11.39  LDD1893 
Exosome complex component RRP40 (EXOSC3) LDTP12434 5.43  LDD1893 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 18.90  LDD1893 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 6.54  LDD1893 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 5.13  LDD1893 
Large proline-rich protein BAG6 (BAG6) LDTP04094 8.17  LDD1893 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 7.01  LDD1893 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 5.86  LDD1893 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 10.34  LDD1893 
Membralin (TMEM259) LDTP14939 7.46  LDD1893 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 5.54  LDD1893 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 9.65  LDD1893 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 9.13  LDD1893 
NLR family member X1 (NLRX1) LDTP08248 5.90  LDD1893 
Nucleobindin-1 (NUCB1) LDTP05375 8.88  LDD1893 
Nucleobindin-2 (NUCB2) LDTP05160 14.52  LDD1893 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 5.31  LDD1893 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 5.70  LDD1893 
Optic atrophy 3 protein (OPA3) LDTP16006 10.20  LDD1893 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 6.92  LDD1893 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 8.17  LDD1893 
Protein CEBPZOS (CEBPZOS) LDTP18883 10.41  LDD1893 
Protein FAM114A2 (FAM114A2) LDTP16080 7.67  LDD1893 
Protein FAM162A (FAM162A) LDTP10056 20.82  LDD1893 
Protein LYRIC (MTDH) LDTP08224 15.45  LDD1893 
Protein SYS1 homolog (SYS1) LDTP08796 6.82  LDD1893 
Protein unc-119 homolog A (UNC119) LDTP05868 44.32  LDD1893 
Protein unc-119 homolog B (UNC119B) LDTP00105 11.88  LDD1893 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 7.26  LDD1893 
Reticulocalbin-1 (RCN1) LDTP06352 6.82  LDD1893 
Reticulocalbin-2 (RCN2) LDTP06097 5.78  LDD1893 
Reticulon-2 (RTN2) LDTP01167 5.90  LDD1893 
Reticulon-3 (RTN3) LDTP01522 24.76  LDD1893 
Reticulon-4 (RTN4) LDTP12412 9.51  LDD1893 
RING finger and SPRY domain-containing protein 1 (RSPRY1) LDTP15712 5.43  LDD1893 
RNA-binding protein 39 (RBM39) LDTP06128 17.51  LDD1893 
RUS family member 1 (RUSF1) LDTP10357 7.41  LDD1893 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 9.51  LDD1893 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 7.46  LDD1893 
Superkiller complex protein 3 (SKIC3) LDTP07574 9.38  LDD1893 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 5.78  LDD1893 
Synaptogyrin-2 (SYNGR2) LDTP00859 6.92  LDD1893 
Syntaxin-10 (STX10) LDTP00986 14.62  LDD1893 
Syntaxin-18 (STX18) LDTP13086 10.06  LDD1893 
Tetraspanin-6 (TSPAN6) LDTP14458 22.47  LDD1893 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 11.55  LDD1893 
TraB domain-containing protein (TRABD) LDTP19963 6.96  LDD1893 
Transmembrane protein 209 (TMEM209) LDTP18272 6.63  LDD1893 
U6 snRNA-associated Sm-like protein LSm7 (LSM7) LDTP13425 9.00  LDD1893 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 19.56  LDD1893 
UBX domain-containing protein 7 (UBXN7) LDTP01451 15.03  LDD1893 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1893 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587