Probe Name	CHEMBL5175495					Probe Info
Probe concentration	20 uM
Criteria	Quantification: Probe vs DMSO
Quantitative Method	LFQ
In Vivo Experiment Model	Model Type			Living cell
	Derived Tissue			Peripheral blood
	Disease Model		Normal
	Model Name		Human normal cells (HEK-293T)

Target ID	Target Name					Binding Ratio
LDTP11178	Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1)					32.5
LDTP07227	Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1)					25.7
LDTP03911	Replication factor C subunit 3 (RFC3)					24.9
LDTP07591	Neutral cholesterol ester hydrolase 1 (NCEH1)					19.0
LDTP10432	ATP synthase membrane subunit K, mitochondrial (ATP5MK)					15.1
LDTP05066	Signal peptidase complex catalytic subunit SEC11A (SEC11A)					14.6
LDTP01514	NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4)					14.5
LDTP09841	Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (ALG3)					14.1
LDTP03540	Heme oxygenase 2 (HMOX2)					13.8
LDTP01462	Endonuclease domain-containing 1 protein (ENDOD1)					12.8
LDTP00697	Cytochrome b5 type B (CYB5B)					12.6
LDTP06787	Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1)					12.2
LDTP02860	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2)					11.9
LDTP02074	Aldehyde dehydrogenase, mitochondrial (ALDH2)					11.7
LDTP12639	1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5)					11.6
LDTP09364	Retinol dehydrogenase 11 (RDH11)					11.5
LDTP04120	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A)					11.4
LDTP14198	Phosphoserine aminotransferase (PSAT1)					10.3
LDTP02067	Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1)					9.9
LDTP01328	CAAX prenyl protease 1 homolog (ZMPSTE24)					9.6
LDTP12415	Adenosine 5'-monophosphoramidase HINT3 (HINT3)					9.6
LDTP14074	Ribosomal biogenesis protein LAS1L (LAS1L)					9.4
LDTP01773	Cytochrome c oxidase subunit 2 (MT-CO2)					9.1
LDTP01039	Protein-S-isoprenylcysteine O-methyltransferase (ICMT)					9.1
LDTP14075	AFG3-like protein 2 (AFG3L2)					8.9
LDTP12867	Very-long-chain enoyl-CoA reductase (TECR)					8.9
LDTP03424	ATP-binding cassette sub-family D member 3 (ABCD3)					8.9
LDTP00192	ATP-dependent RNA helicase DDX39A (DDX39A)					8.5
LDTP06657	2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8)					8.5
LDTP04285	Proteasome subunit beta type-2 (PSMB2)					8.5
LDTP02264	Asparagine synthetase [glutamine-hydrolyzing] (ASNS)					8.3
LDTP02640	X-ray repair cross-complementing protein 6 (XRCC6)					8.2
LDTP13989	Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2)					8.2
LDTP10930	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1)					8.1
LDTP12954	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3)					8.1
LDTP03487	Transketolase (TKT)					8.1
LDTP03522	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A)					8.0
LDTP01219	NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1)					7.7
LDTP00714	26S proteasome non-ATPase regulatory subunit 3 (PSMD3)					7.6
LDTP02179	L-lactate dehydrogenase B chain (LDHB)					7.6
LDTP03847	Transaldolase (TALDO1)					7.6
LDTP11070	Vitamin K epoxide reductase complex subunit 1 (VKORC1)					7.6
LDTP01766	L-lactate dehydrogenase A chain (LDHA)					7.4
LDTP01273	Acyl-protein thioesterase 1 (LYPLA1)					7.4
LDTP02225	Heat shock protein HSP 90-alpha (HSP90AA1)					7.4
LDTP03510	Peroxiredoxin-6 (PRDX6)					7.4
LDTP17476	Protein C-mannosyl-transferase DPY19L3 (DPY19L3)					7.4
LDTP03156	Trifunctional purine biosynthetic protein adenosine-3 (GART)					7.4
LDTP12776	Sphingomyelin phosphodiesterase 4 (SMPD4)					7.3
LDTP05074	Tubulin alpha-1B chain (TUBA1B)					7.3
LDTP05550	ATP-dependent RNA helicase A (DHX9)					7.2
LDTP03577	S-adenosylmethionine synthase isoform type-2 (MAT2A)					7.2
LDTP05991	Spliceosome RNA helicase DDX39B (DDX39B)					7.2
LDTP01205	Citrate synthase, mitochondrial (CS)					7.2
LDTP03242	Adenosylhomocysteinase (AHCY)					7.2
LDTP02283	Cytochrome c1, heme protein, mitochondrial (CYC1)					7.1
LDTP09495	Probable glutathione peroxidase 8 (GPX8)					7.1
LDTP05071	Elongation factor 1-alpha 1 (EEF1A1)					7.1
LDTP08296	Cullin-associated NEDD8-dissociated protein 1 (CAND1)					7.0
LDTP04499	6-phosphogluconate dehydrogenase, decarboxylating (PGD)					7.0
LDTP02672	Elongation factor 2 (EEF2)					7.0
LDTP14213	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG6)					7.0
LDTP00701	D-3-phosphoglycerate dehydrogenase (PHGDH)					7.0
LDTP04878	Eukaryotic initiation factor 4A-I (EIF4A1)					7.0
LDTP06270	Signal peptidase complex subunit 2 (SPCS2)					6.9
LDTP03223	Small ribosomal subunit protein uS3 (RPS3)					6.9
LDTP07362	Atlastin-3 (ATL3)					6.9
LDTP01047	Dolichol-phosphate mannosyltransferase subunit 1 (DPM1)					6.9
LDTP05128	Glutathione S-transferase omega-1 (GSTO1)					6.8
LDTP06192	Neutral alpha-glucosidase AB (GANAB)					6.7
LDTP06810	Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50)					6.7
LDTP02580	C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1)					6.7
LDTP02149	Cyclin-dependent kinase 1 (CDK1)					6.7
LDTP03159	Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS)					6.6
LDTP02642	X-ray repair cross-complementing protein 5 (XRCC5)					6.6
LDTP02522	60 kDa heat shock protein, mitochondrial (HSPD1)					6.6
LDTP05059	Actin, cytoplasmic 2 (ACTG1)					6.5
LDTP03900	ADP-ribosylation factor-like protein 1 (ARL1)					6.5
LDTP01374	Glutaredoxin-3 (GLRX3)					6.4
LDTP02375	Poly [ADP-ribose] polymerase 1 (PARP1)					6.4
LDTP02188	Protein disulfide-isomerase (P4HB)					6.4
LDTP08728	Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1)					6.4
LDTP04909	ATP-binding cassette sub-family E member 1 (ABCE1)					6.3
LDTP04895	Ras-related protein Rab-10 (RAB10)					6.3
LDTP02150	ATP synthase subunit beta, mitochondrial (ATP5F1B)					6.3
LDTP06432	Pachytene checkpoint protein 2 homolog (TRIP13)					6.3
LDTP05007	GTP-binding nuclear protein Ran (RAN)					6.3
LDTP06901	Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12)					6.2
LDTP13189	Cytochrome b-c1 complex subunit 9 (UQCR10)					6.2
LDTP03817	Lon protease homolog, mitochondrial (LONP1)					6.2
LDTP12293	Adipocyte plasma membrane-associated protein (APMAP)					6.1
LDTP06286	116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2)					6.1
LDTP12227	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2)					6.1
LDTP02220	Adenine phosphoribosyltransferase (APRT)					6.0
LDTP06721	GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11)					6.0
LDTP05409	Antigen peptide transporter 2 (TAP2)					6.0
LDTP02942	ADP-ribosylation factor 4 (ARF4)					6.0
LDTP03861	Eukaryotic initiation factor 4A-III (EIF4A3)					5.9
LDTP10329	Ceramide synthase 2 (CERS2)					5.8
LDTP09396	Minor histocompatibility antigen H13 (HM13)					5.8
LDTP00464	Glutathione S-transferase 3, mitochondrial (MGST3)					5.6
LDTP11127	ADP-dependent glucokinase (ADPGK)					5.5
LDTP03419	Proteasome subunit beta type-5 (PSMB5)					5.5
LDTP03316	DNA replication licensing factor MCM3 (MCM3)					5.4
LDTP03676	ATP-binding cassette sub-family D member 1 (ABCD1)					5.4
LDTP02021	Ornithine aminotransferase, mitochondrial (OAT)					5.3
LDTP04561	ATP-citrate synthase (ACLY)					5.3
LDTP06294	Lysine--tRNA ligase (KARS1)					5.2

Target ID	Target Name					Binding Ratio
LDTP01060	PRA1 family protein 2 (PRAF2)					15.6
LDTP14235	Mitochondrial carrier homolog 2 (MTCH2)					14.5
LDTP01969	Transferrin receptor protein 1 (TFRC)					14.3
LDTP13824	Voltage-dependent anion-selective channel protein 3 (VDAC3)					14.1
LDTP06490	Vesicle-associated membrane protein 3 (VAMP3)					14.1
LDTP04071	Voltage-dependent anion-selective channel protein 2 (VDAC2)					13.4
LDTP05292	Fatty acid-binding protein 5 (FABP5)					13.3
LDTP05511	Cytoskeleton-associated protein 4 (CKAP4)					13.1
LDTP10081	Leucine-rich repeat-containing protein 59 (LRRC59)					11.9
LDTP00541	NPC intracellular cholesterol transporter 1 (NPC1)					11.7
LDTP02256	Amino acid transporter heavy chain SLC3A2 (SLC3A2)					11.7
LDTP13823	Mitochondrial chaperone BCS1 (BCS1L)					11.0
LDTP06462	Neutral amino acid transporter B(0) (SLC1A5)					10.9
LDTP02058	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2)					10.8
LDTP02247	Annexin A6 (ANXA6)					10.7
LDTP09547	Scavenger receptor class B member 1 (SCARB1)					10.6
LDTP00235	Membrane-associated progesterone receptor component 1 (PGRMC1)					10.4
LDTP15838	Translocation protein SEC62 (SEC62)					10.4
LDTP03132	Voltage-dependent anion-selective channel protein 1 (VDAC1)					10.4
LDTP03717	Prohibitin 1 (PHB1)					10.3
LDTP04849	CD81 antigen (CD81)					10.0
LDTP05875	Transmembrane emp24 domain-containing protein 1 (TMED1)					10.0
LDTP03559	High affinity cationic amino acid transporter 1 (SLC7A1)					9.9
LDTP02609	ADP/ATP translocase 3 (SLC25A6)					9.5
LDTP12210	Mitochondrial thiamine pyrophosphate carrier (SLC25A19)					9.5
LDTP04426	B-cell receptor-associated protein 31 (BCAP31)					9.5
LDTP04187	CD151 antigen (CD151)					9.3
LDTP02087	ADP/ATP translocase 2 (SLC25A5)					9.2
LDTP13834	Sodium-dependent multivitamin transporter (SLC5A6)					9.1
LDTP04662	Exportin-2 (CSE1L)					8.9
LDTP05305	Large neutral amino acids transporter small subunit 1 (SLC7A5)					8.9
LDTP08030	Autophagy-related protein 9A (ATG9A)					8.9
LDTP10985	Equilibrative nucleoside transporter 1 (SLC29A1)					8.8
LDTP12090	Sideroflexin-1 (SFXN1)					8.8
LDTP03405	Calnexin (CANX)					8.7
LDTP04391	T-complex protein 1 subunit delta (CCT4)					8.1
LDTP05238	Solute carrier family 25 member 3 (SLC25A3)					8.1
LDTP04624	Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3)					8.1
LDTP12191	Vezatin (VEZT)					8.0
LDTP05043	14-3-3 protein zeta/delta (YWHAZ)					7.9
LDTP13943	Thioredoxin-related transmembrane protein 2 (TMX2)					7.9
LDTP06242	Importin subunit beta-1 (KPNB1)					7.8
LDTP03810	ATP synthase subunit gamma, mitochondrial (ATP5F1C)					7.8
LDTP00451	Secretory carrier-associated membrane protein 3 (SCAMP3)					7.7
LDTP00266	Importin-5 (IPO5)					7.6
LDTP02307	Annexin A5 (ANXA5)					7.5
LDTP01745	Putative lipid scramblase CLPTM1 (CLPTM1)					7.5
LDTP04592	Monocarboxylate transporter 1 (SLC16A1)					7.5
LDTP04938	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (DAD1)					7.5
LDTP12142	Exportin-5 (XPO5)					7.4
LDTP04932	Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1)					7.4
LDTP15979	Transmembrane protein 245 (TMEM245)					7.4
LDTP13243	Translocation protein SEC63 homolog (SEC63)					7.3
LDTP04787	Transmembrane protein 33 (TMEM33)					7.3
LDTP09788	Sorting nexin-19 (SNX19)					7.3
LDTP02262	Heat shock protein HSP 90-beta (HSP90AB1)					7.2
LDTP12909	Mitochondrial carrier homolog 1 (MTCH1)					7.2
LDTP07053	Cytochrome c oxidase assembly protein COX20, mitochondrial (COX20)					7.2
LDTP01631	Mitochondrial pyruvate carrier 2 (MPC2)					7.2
LDTP01037	Catenin delta-1 (CTNND1)					7.1
LDTP05040	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (GNAS)					7.0
LDTP13320	Prenylated Rab acceptor protein 1 (RABAC1)					6.9
LDTP11824	Sodium-coupled neutral amino acid symporter 1 (SLC38A1)					6.8
LDTP04082	Ran GTPase-activating protein 1 (RANGAP1)					6.7
LDTP01748	Mitochondrial import receptor subunit TOM40 homolog (TOMM40)					6.6
LDTP04969	14-3-3 protein epsilon (YWHAE)					6.6
LDTP04501	Importin subunit alpha-1 (KPNA2)					6.5
LDTP02658	Cytochrome b-245 light chain (CYBA)					6.5
LDTP12510	Aladin (AAAS)					6.5
LDTP00127	Nuclear envelope pore membrane protein POM 121C (POM121C)					6.4
LDTP06034	Lysosome membrane protein 2 (SCARB2)					6.4
LDTP14952	Mpv17-like protein 2 (MPV17L2)					6.4
LDTP11245	Derlin-1 (DERL1)					6.4
LDTP07058	Transmembrane protein 201 (TMEM201)					6.2
LDTP03385	14-3-3 protein theta (YWHAQ)					6.2
LDTP01574	Importin-7 (IPO7)					5.8
LDTP00014	Extended synaptotagmin-2 (ESYT2)					5.8
LDTP00590	Protein RER1 (RER1)					5.7
LDTP06660	MICOS complex subunit MIC60 (IMMT)					5.5
LDTP00501	Exportin-1 (XPO1)					5.5
LDTP10885	Sortilin (SORT1)					5.4
LDTP20002	Transmembrane protein 160 (TMEM160)					5.4
LDTP13174	Mitochondrial dicarboxylate carrier (SLC25A10)					5.2

Target ID	Target Name					Binding Ratio
LDTP10501	DnaJ homolog subfamily C member 1 (DNAJC1)					10.1
LDTP07940	eIF5-mimic protein 2 (BZW1)					6.6

Target ID	Target Name					Binding Ratio
LDTP05572	Leukocyte surface antigen CD47 (CD47)					12.0
LDTP05819	Inactive tyrosine-protein kinase 7 (PTK7)					10.8

Target ID	Target Name					Binding Ratio
LDTP04355	Rab GDP dissociation inhibitor beta (GDI2)					22.3
LDTP11140	Peroxiredoxin-like 2A (PRXL2A)					16.1
LDTP12412	Reticulon-4 (RTN4)					16.1
LDTP05257	Receptor expression-enhancing protein 5 (REEP5)					16.1
LDTP01522	Reticulon-3 (RTN3)					16.0
LDTP10924	Prohibitin-2 (PHB2)					13.4
LDTP03968	Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO)					11.5
LDTP16323	Signal recognition particle receptor subunit beta (SRPRB)					10.7
LDTP09787	Nicastrin (NCSTN)					10.4
LDTP12755	OCIA domain-containing protein 1 (OCIAD1)					10.2
LDTP15110	Protein C3orf33 (C3orf33)					8.9
LDTP11981	Receptor expression-enhancing protein 4 (REEP4)					8.7
LDTP04094	Large proline-rich protein BAG6 (BAG6)					8.7
LDTP15253	HEAT repeat-containing protein 3 (HEATR3)					8.3
LDTP14458	Tetraspanin-6 (TSPAN6)					8.2
LDTP08902	CDGSH iron-sulfur domain-containing protein 2 (CISD2)					8.1
LDTP05697	Heat shock protein 75 kDa, mitochondrial (TRAP1)					8.1
LDTP13828	Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3)					7.9
LDTP02692	Plastin-3 (PLS3)					7.9
LDTP04913	Small ribosomal subunit protein eS1 (RPS3A)					7.7
LDTP13664	Syntaxin-8 (STX8)					7.7
LDTP02809	Small ribosomal subunit protein uS5 (RPS2)					7.5
LDTP03503	Myristoylated alanine-rich C-kinase substrate (MARCKS)					7.5
LDTP00398	Insulin receptor substrate 4 (IRS4)					7.5
LDTP03367	Elongation factor 1-gamma (EEF1G)					7.4
LDTP05421	Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1)					7.4
LDTP05024	Large ribosomal subunit protein uL1 (RPL10A)					7.2
LDTP10990	T-complex protein 1 subunit eta (CCT7)					7.2
LDTP02109	Large ribosomal subunit protein uL10 (RPLP0)					7.2
LDTP03364	Polypyrimidine tract-binding protein 1 (PTBP1)					7.2
LDTP11079	Myb-binding protein 1A (MYBBP1A)					7.0
LDTP00551	Actin-related protein 2/3 complex subunit 2 (ARPC2)					7.0
LDTP03997	Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC)					7.0
LDTP02734	Endoplasmin (HSP90B1)					7.0
LDTP02944	Large ribosomal subunit protein uL30 (RPL7)					7.0
LDTP15874	Mitochondrial import inner membrane translocase subunit Tim29 (TIMM29)					6.9
LDTP04390	T-complex protein 1 subunit theta (CCT8)					6.8
LDTP06367	Poly(rC)-binding protein 2 (PCBP2)					6.8
LDTP02205	Tubulin beta chain (TUBB)					6.8
LDTP04965	Small ribosomal subunit protein uS8 (RPS15A)					6.7
LDTP08058	Mitochondrial antiviral-signaling protein (MAVS)					6.7
LDTP04109	Small ribosomal subunit protein uS4 (RPS9)					6.6
LDTP03395	Large ribosomal subunit protein uL16 (RPL10)					6.5
LDTP13091	Ataxin-10 (ATXN10)					6.5
LDTP05688	Interleukin enhancer-binding factor 2 (ILF2)					6.4
LDTP04249	T-complex protein 1 subunit gamma (CCT3)					6.4
LDTP19955	DnaJ homolog subfamily C member 25 (DNAJC25)					6.4
LDTP03865	Large ribosomal subunit protein uL3 (RPL3)					6.4
LDTP05076	Tubulin beta-4B chain (TUBB4B)					6.3
LDTP06373	Mitochondrial import receptor subunit TOM20 homolog (TOMM20)					6.2
LDTP04971	Small ribosomal subunit protein uS12 (RPS23)					6.1
LDTP05689	Interleukin enhancer-binding factor 3 (ILF3)					6.1
LDTP04966	Small ribosomal subunit protein uS9 (RPS16)					6.0
LDTP13143	Eukaryotic translation initiation factor 3 subunit K (EIF3K)					6.0
LDTP09938	Far upstream element-binding protein 2 (KHSRP)					6.0
LDTP03695	Heat shock 70 kDa protein 4 (HSPA4)					6.0
LDTP04975	Small ribosomal subunit protein uS17 (RPS11)					5.9
LDTP02306	Guanine nucleotide-binding protein G(i) subunit alpha-3 (GNAI3)					5.9
LDTP06366	Poly(rC)-binding protein 1 (PCBP1)					5.8
LDTP04844	Actin-related protein 2/3 complex subunit 4 (ARPC4)					5.8
LDTP10056	Protein FAM162A (FAM162A)					5.8
LDTP06543	DNA damage-binding protein 1 (DDB1)					5.7
LDTP04110	Small ribosomal subunit protein uS7 (RPS5)					5.7
LDTP05113	T-complex protein 1 subunit beta (CCT2)					5.6
LDTP07598	BRCA1-associated ATM activator 1 (BRAT1)					5.6
LDTP13813	Eukaryotic translation initiation factor 3 subunit L (EIF3L)					5.6
LDTP00858	Synaptogyrin-1 (SYNGR1)					5.6
LDTP00313	Nucleolar protein 56 (NOP56)					5.6
LDTP03815	Large ribosomal subunit protein uL4 (RPL4)					5.6
LDTP11040	Condensin complex subunit 3 (NCAPG)					5.6
LDTP04997	Small ribosomal subunit protein eS4, X isoform (RPS4X)					5.6
LDTP03658	Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9)					5.5
LDTP02934	T-complex protein 1 subunit alpha (TCP1)					5.4
LDTP15880	Mitochondrial nucleoid-associated protein 1 (MTNAP1)					5.3
LDTP00223	26S proteasome non-ATPase regulatory subunit 11 (PSMD11)					5.2

1	Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20. ACS Med Chem Lett. 2022 Sep 26;13(10):1648-1654. doi: 10.1021/acsmedchemlett.2c00336. eCollection 2022 Oct 13.