Details of the Target

General Information of Target

Target ID LDTP19955
Target Name DnaJ homolog subfamily C member 25 (DNAJC25)
Gene Name DNAJC25
Gene ID 548645
Synonyms
DnaJ homolog subfamily C member 25
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAPQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDC
QANNICCSTYCGNVCMSIL
Target Bioclass
Other
Family
DNAJC25 family
Subcellular location
Membrane
Uniprot ID
Q9H1X3
Ensemble ID
ENST00000313525.4
HGNC ID
HGNC:34187

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HEC1 SNV: p.Y343C .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
CHEMBL5175495
 Probe Info  		6.37  LDD0196  [1]

References

1 Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20. ACS Med Chem Lett. 2022 Sep 26;13(10):1648-1654. doi: 10.1021/acsmedchemlett.2c00336. eCollection 2022 Oct 13.