Details of the Target

General Information of Target

Target ID LDTP11040
Target Name Condensin complex subunit 3 (NCAPG)
Gene Name NCAPG
Gene ID 64151
Synonyms
CAPG; NYMEL3; Condensin complex subunit 3; Chromosome-associated protein G; Condensin subunit CAP-G; hCAP-G; Melanoma antigen NY-MEL-3; Non-SMC condensin I complex subunit G; XCAP-G homolog
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL
CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT
LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN
CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG
IELLVTGGAELGYGCKASRSTPVDAPDIPS
Target Bioclass
Other
Family
CND3 (condensin subunit 3) family
Subcellular location
Nucleus
Function
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Uniprot ID
Q9BPX3
Ensemble ID
ENST00000251496.7
HGNC ID
HGNC:24304

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 28 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		13.77  LDD0402  [1]
CHEMBL5175495
 Probe Info  		5.56  LDD0196  [2]
ONAyne
 Probe Info  		K11(3.47)  LDD0274  [3]
STPyne
 Probe Info  		K1001(10.00); K11(6.67); K152(0.79); K221(1.94)  LDD0277  [3]
BTD
 Probe Info  		C202(1.97)  LDD1700  [4]
AHL-Pu-1
 Probe Info  		C835(2.18); C667(2.62); C202(2.00)  LDD0168  [5]
DBIA
 Probe Info  		C610(4.28); C611(4.28); C835(2.92); C843(2.92)  LDD0080  [6]
5E-2FA
 Probe Info  		N.A.  LDD2235  [7]
ATP probe
 Probe Info  		K522(0.00); K26(0.00); K491(0.00)  LDD0199  [8]
4-Iodoacetamidophenylacetylene
 Probe Info  		C509(0.00); C751(0.00); C119(0.00); C177(0.00)  LDD0038  [9]
IA-alkyne
 Probe Info  		C177(0.00); C835(0.00); C509(0.00); C202(0.00)  LDD0032  [10]
IPIAA_L
 Probe Info  		N.A.  LDD0031  [11]
Lodoacetamide azide
 Probe Info  		C202(0.00); C509(0.00); C751(0.00); C119(0.00)  LDD0037  [9]
NAIA_4
 Probe Info  		N.A.  LDD2226  [12]
TFBX
 Probe Info  		N.A.  LDD0027  [13]
WYneN
 Probe Info  		N.A.  LDD0021  [14]
WYneO
 Probe Info  		N.A.  LDD0022  [14]
Compound 10
 Probe Info  		N.A.  LDD2216  [15]
IPM
 Probe Info  		N.A.  LDD0005  [14]
NHS
 Probe Info  		N.A.  LDD0010  [14]
VSF
 Probe Info  		N.A.  LDD0007  [14]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [16]
Acrolein
 Probe Info  		C509(0.00); C843(0.00); C202(0.00)  LDD0217  [17]
Crotonaldehyde
 Probe Info  		C843(0.00); C509(0.00); C202(0.00)  LDD0219  [17]
Methacrolein
 Probe Info  		C509(0.00); C202(0.00); C843(0.00)  LDD0218  [17]
W1
 Probe Info  		C202(0.00); C835(0.00); C843(0.00); C751(0.00)  LDD0236  [18]
AOyne
 Probe Info  		6.20  LDD0443  [19]
NAIA_5
 Probe Info  		N.A.  LDD2223  [12]
PAL-AfBPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe13
 Probe Info  		20.00  LDD0475  [20]
FFF probe3
 Probe Info  		6.40  LDD0465  [20]
STS-2
 Probe Info  		N.A.  LDD0138  [21]
VE-P
 Probe Info  		N.A.  LDD0396  [22]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C202(0.58); C119(0.42)  LDD2095  [4]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C202(0.71); C119(0.46)  LDD2130  [4]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C119(1.09); C843(1.14)  LDD2117  [4]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C202(1.03)  LDD2152  [4]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C202(0.44); C119(0.47)  LDD2132  [4]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C202(0.76)  LDD2131  [4]
 LDCM0025  4SU-RNA HEK-293T C835(2.18); C667(2.62); C202(2.00)  LDD0168  [5]
 LDCM0026  4SU-RNA+native RNA HEK-293T C667(2.95)  LDD0169  [5]
 LDCM0214  AC1 HCT 116 C119(1.08); C202(0.97); C607(0.74); C610(0.81)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C119(0.91); C202(1.09); C607(0.76); C610(1.00)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C119(0.77); C607(0.45); C610(0.46); C611(0.65)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C119(0.65); C607(0.54); C610(0.53); C611(0.72)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C119(0.71); C607(0.43); C610(0.41); C611(0.60)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C119(0.66); C607(0.47); C610(0.45); C611(0.63)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C119(0.82); C607(0.52); C610(0.48); C611(0.65)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C119(0.67); C607(0.51); C610(0.47); C611(0.65)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C119(0.76); C607(0.61); C610(0.50); C611(0.64)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C119(0.77); C607(0.56); C610(0.49); C611(0.79)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C119(0.80); C607(0.38); C610(0.59); C611(0.73)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C119(0.84); C607(0.56); C610(0.49); C611(0.62)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C119(0.88); C202(0.92); C607(0.84); C610(0.98)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C119(0.74); C607(0.53); C610(0.51); C611(0.68)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C119(0.70); C607(0.58); C610(0.49); C611(0.57)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C119(0.74); C607(0.57); C610(0.42); C611(0.53)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C119(0.94); C202(0.95); C607(0.95); C610(1.01)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C119(0.80); C202(1.04); C607(0.76); C610(0.94)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C119(0.79); C202(0.93); C607(1.09); C610(0.93)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C119(0.81); C202(0.81); C607(0.90); C610(0.95)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C119(0.82); C202(0.97); C607(1.05); C610(0.97)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C119(0.89); C202(1.01); C607(0.74); C610(0.93)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C119(0.87); C202(0.96); C607(0.76); C610(0.88)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C119(1.05); C202(1.10); C607(0.83); C610(0.81)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C119(0.81); C202(1.01); C607(0.57); C610(0.96)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C119(1.08); C202(1.08); C607(0.76); C610(1.02)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C119(0.87); C202(0.93); C607(1.20); C610(0.93)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C119(0.90); C202(1.22); C607(1.15); C610(0.98)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C119(1.01); C202(1.19); C607(0.83); C610(1.13)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C119(0.87); C202(1.05); C607(1.16); C610(1.10)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C119(0.85); C202(1.11); C607(0.69); C610(1.03)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C119(0.82); C202(1.15); C607(0.85); C610(1.01)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C119(1.39); C202(0.87); C610(1.48); C611(1.56)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C119(1.46); C202(0.72); C610(1.32); C611(1.47)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C119(1.37); C202(0.92); C610(1.29); C611(1.31)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C119(1.30); C202(0.95); C610(1.18); C611(1.26)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C119(1.25); C202(0.87); C610(1.35); C611(1.39)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C119(1.29); C202(0.90); C610(1.24); C611(1.29)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C119(1.16); C202(0.85); C610(1.29); C611(1.36)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C119(1.30); C202(0.86); C610(1.45); C611(1.56)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C119(1.30); C202(0.81); C610(1.12); C611(1.19)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C119(1.23); C202(0.90); C610(1.09); C611(1.18)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C119(1.23); C202(0.83); C610(1.25); C611(1.33)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C119(1.22); C202(0.97); C610(1.28); C611(1.39)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C119(0.95); C202(0.94); C607(0.80); C610(1.02)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C119(1.19); C202(0.77); C610(1.26); C611(1.37)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C119(1.13); C202(0.86); C610(1.15); C611(1.33)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C119(1.33); C202(0.86); C610(1.25); C611(1.31)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C835(0.90); C610(0.98); C611(0.98); C119(1.00)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C843(0.93); C202(0.98); C610(1.03); C611(1.08)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C843(0.88); C610(0.91); C611(1.01); C119(1.17)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C611(0.85); C843(0.93); C835(0.94); C610(0.96)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C610(0.92); C843(0.95); C202(0.97); C611(1.03)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C835(1.05); C119(1.07); C610(1.20); C843(1.23)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C835(0.83); C119(0.95); C611(1.02); C843(1.06)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C835(0.90); C119(0.91); C843(0.92); C202(0.94)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C611(0.87); C610(0.90); C119(0.95); C843(1.04)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C843(0.96); C610(1.00); C611(1.01); C835(1.02)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C611(0.90); C835(0.95); C610(0.98); C119(1.07)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C835(0.89); C119(1.00); C610(1.02); C611(1.05)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C119(1.42); C202(1.23); C610(0.95); C611(0.95)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C119(1.16); C202(1.32); C610(0.93); C611(0.90)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C119(1.04); C202(1.15); C610(1.09); C611(0.99)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C119(1.12); C202(1.22); C610(1.13); C611(1.12)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C119(0.88); C843(0.90); C610(0.92); C202(0.92)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C607(0.50); C610(0.61); C611(0.84); C119(0.84)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C607(0.71); C610(0.83); C119(0.85); C202(0.89)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C751(0.70); C607(0.87); C835(0.92); C202(0.93)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C607(0.72); C610(0.82); C119(0.85); C611(1.01)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C119(0.84); C610(0.87); C607(0.87); C843(0.98)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C607(0.92); C119(0.94); C202(1.03); C610(1.07)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C607(0.81); C119(0.88); C610(0.95); C202(1.03)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C607(0.89); C119(0.91); C202(1.01); C610(1.05)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C751(0.72); C843(0.88); C835(0.92); C119(0.92)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C751(0.73); C119(0.81); C202(0.83); C843(0.83)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C119(0.73); C843(0.84); C835(0.85); C610(0.88)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C119(0.75); C751(0.76); C843(0.88); C835(0.94)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C119(0.74); C843(0.82); C835(0.86); C751(0.89)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C751(0.66); C607(0.85); C610(0.86); C611(0.86)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C119(0.79); C751(0.84); C843(0.89); C835(0.91)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C751(0.70); C843(0.87); C835(0.89); C119(0.91)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C119(0.79); C751(0.79); C202(0.80); C835(0.80)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C119(0.67); C843(0.80); C835(0.80); C751(0.87)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C119(0.76); C835(0.77); C843(0.77); C751(0.86)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C610(0.67); C611(0.74); C843(0.81); C835(0.97)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C751(0.80); C843(0.88); C610(0.93); C835(0.95)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C610(0.87); C611(0.87); C751(0.94); C119(1.04)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C751(0.78); C610(0.88); C611(0.90); C835(0.96)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C751(0.75); C610(0.76); C611(0.81); C843(0.91)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C751(0.69); C607(0.78); C835(0.87); C610(0.93)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C843(0.90); C610(0.92); C611(0.94); C751(0.96)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C751(0.63); C835(0.91); C610(0.95); C843(0.95)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C751(0.78); C610(0.94); C119(0.96); C611(0.98)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C751(0.82); C611(0.91); C610(0.91); C202(0.99)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C751(0.73); C835(0.90); C843(0.91); C611(0.99)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C751(0.86); C843(0.94); C611(0.97); C610(1.00)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C610(0.92); C611(0.97); C202(1.04); C751(1.04)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C610(0.92); C751(0.93); C611(0.96); C202(1.04)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C751(0.85); C610(0.92); C202(0.95); C611(0.96)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C202(1.00); C611(1.01); C610(1.01); C835(1.02)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C751(0.67); C607(0.69); C610(0.84); C611(0.87)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C835(0.98); C202(1.03); C610(1.03); C611(1.07)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C610(0.93); C611(0.95); C843(0.98); C202(1.04)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C202(0.90); C610(0.96); C751(0.97); C611(1.00)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C202(1.02); C119(1.06); C610(1.08); C611(1.10)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C611(0.97); C202(1.00); C610(1.00); C119(1.00)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C610(0.98); C611(1.01); C202(1.08); C843(1.12)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C202(1.11); C610(1.16); C611(1.23); C843(1.51)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C202(0.72); C835(0.78); C843(0.93); C610(0.94)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C202(0.73); C610(0.93); C835(0.93); C119(0.93)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C202(0.65); C835(0.89); C843(0.92); C610(0.98)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C119(0.81); C835(0.83); C843(0.86); C202(0.92)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C202(0.63); C835(0.79); C843(0.88); C119(0.94)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C843(0.78); C202(0.79); C835(0.81); C119(0.94)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C202(0.69); C119(0.96); C835(0.97); C843(0.99)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C202(0.69); C610(0.89); C611(0.97); C119(1.03)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C202(0.68); C835(1.06); C119(1.11); C843(1.13)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C202(0.65); C835(0.93); C843(0.94); C119(1.04)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C202(0.72); C835(0.98); C843(0.99); C119(1.10)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C202(0.70); C835(0.99); C610(0.99); C611(0.99)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C751(0.84); C119(0.88); C610(0.98); C202(1.03)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C610(0.81); C611(0.85); C119(0.93); C202(1.10)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C835(0.90); C202(0.92); C843(0.92); C119(0.94)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C610(0.81); C611(0.84); C119(0.93); C751(0.98)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C119(0.97); C610(1.02); C835(1.04); C202(1.10)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C119(0.85); C610(0.92); C611(0.94); C835(0.96)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C119(1.08); C610(1.08); C751(1.09); C611(1.11)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C751(1.02); C611(1.07); C610(1.11); C119(1.13)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C751(1.05); C202(1.20); C119(1.20); C611(1.24)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C119(0.95); C751(0.97); C610(1.03); C202(1.07)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C119(0.95); C610(1.01); C202(1.05); C751(1.05)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C610(0.92); C751(1.00); C202(1.03); C119(1.07)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C119(0.90); C610(0.95); C202(1.00); C835(1.02)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C607(0.72); C119(0.84); C610(0.86); C611(0.93)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C610(0.93); C119(0.97); C202(1.01); C611(1.06)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C119(0.94); C751(0.99); C610(1.00); C611(1.04)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C751(0.95); C610(1.06); C611(1.21); C202(1.33)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C835(0.75); C119(0.78); C610(0.85); C611(0.87)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C835(0.77); C119(0.78); C202(0.92); C610(0.92)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C119(0.76); C611(0.81); C610(0.82); C835(0.84)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C119(0.77); C202(0.84); C611(0.86); C835(0.87)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C119(0.89); C610(0.91); C611(0.91); C202(0.91)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C119(0.78); C611(0.86); C202(0.92); C610(0.93)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C119(0.74); C202(0.83); C611(0.89); C835(0.94)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C835(0.88); C843(0.95); C202(0.97); C610(0.98)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C119(0.79); C202(0.96); C835(0.97); C611(1.01)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C610(0.73); C611(0.74); C119(0.81); C835(0.87)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C610(0.63); C611(0.65); C119(0.76); C202(0.84)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C119(0.85); C202(0.91); C611(0.93); C610(0.99)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C119(0.82); C202(0.86); C611(0.87); C610(0.88)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C119(0.80); C202(0.96); C611(0.99); C610(0.99)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C119(0.73); C835(0.82); C202(0.86); C611(0.88)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C607(0.33); C610(0.47); C119(0.62); C611(0.65)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C610(0.50); C607(0.54); C611(0.64); C119(0.74)  LDD0683  [6]
 LDCM0545  Acetamide MDA-MB-231 C202(0.52)  LDD2138  [4]
 LDCM0520  AKOS000195272 MDA-MB-231 C202(0.98)  LDD2113  [4]
 LDCM0248  AKOS034007472 HCT 116 C119(1.14); C202(1.01); C607(1.03); C610(1.19)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C119(0.88); C202(0.89); C835(0.91); C843(0.94)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C119(0.87); C202(0.96); C607(0.99); C835(1.00)  LDD0592  [6]
 LDCM0156  Aniline NCI-H1299 N.A.  LDD0405  [1]
 LDCM0102  BDHI 8 Jurkat C835(8.61); C843(8.61)  LDD0204  [23]
 LDCM0498  BS-3668 MDA-MB-231 C202(0.64); C119(0.71)  LDD2091  [4]
 LDCM0108  Chloroacetamide HeLa C509(0.00); H286(0.00); C843(0.00)  LDD0222  [17]
 LDCM0632  CL-Sc Hep-G2 C202(2.77); C667(1.45); C966(1.04); C966(0.82)  LDD2227  [12]
 LDCM0367  CL1 HCT 116 C611(0.87); C610(0.88); C202(0.92); C843(0.96)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C202(0.90); C611(0.93); C610(0.97); C751(1.05)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C607(0.77); C751(0.82); C610(0.84); C611(0.87)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C119(0.76); C202(0.91); C843(0.92); C835(0.93)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C202(0.90); C119(0.94); C835(0.95); C843(0.97)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C607(0.94); C202(0.96); C835(0.97); C843(0.98)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C202(0.87); C119(0.93); C835(0.98); C843(0.98)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C607(0.80); C119(0.86); C610(0.87); C202(0.91)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C607(0.60); C610(0.76); C611(0.95); C202(0.97)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C607(0.64); C610(0.69); C119(0.86); C202(0.90)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C607(0.72); C610(0.77); C119(0.88); C202(0.93)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C119(0.76); C607(0.83); C610(0.83); C202(0.89)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C202(0.86); C611(0.97); C610(0.99); C119(1.14)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C607(0.74); C119(0.77); C610(0.84); C202(0.89)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C607(0.73); C610(0.78); C119(0.82); C202(0.84)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C751(0.69); C610(0.89); C202(0.89); C843(0.92)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C843(0.79); C835(0.80); C751(0.80); C119(0.88)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C202(0.77); C751(0.81); C835(0.82); C843(0.85)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C751(0.71); C835(0.78); C119(0.78); C843(0.80)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C751(0.57); C835(0.77); C119(0.77); C843(0.78)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C610(1.02); C843(1.03); C751(1.05); C611(1.09)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C610(0.80); C611(0.81); C751(0.81); C835(0.94)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C610(0.84); C611(0.85); C843(0.93); C751(0.95)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C202(1.03); C835(1.05); C611(1.05); C610(1.07)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C751(0.73); C843(0.84); C610(0.88); C611(0.92)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C843(0.82); C119(0.84); C202(0.87); C611(0.95)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C202(0.91); C610(0.95); C611(0.99); C751(1.06)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C610(0.88); C202(0.90); C611(0.90); C119(1.06)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C610(0.97); C202(0.98); C611(1.04); C119(1.15)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C202(0.74); C610(0.93); C835(0.96); C611(0.97)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C202(0.68); C119(0.86); C843(0.88); C835(0.88)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C202(0.74); C835(0.78); C843(0.79); C610(0.94)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C202(0.76); C843(0.86); C610(0.91); C119(0.91)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C202(0.86); C610(0.92); C611(0.93); C835(0.95)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C202(0.87); C843(0.88); C835(0.88); C611(0.89)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C202(0.83); C751(0.88); C610(0.88); C611(0.89)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C119(0.85); C751(0.89); C611(0.92); C610(0.98)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C751(0.79); C611(0.91); C119(0.91); C202(0.94)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C835(0.87); C119(0.87); C202(0.89); C611(0.94)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C119(0.87); C835(0.93); C751(0.99); C611(1.06)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C611(0.83); C751(0.85); C610(0.86); C835(0.94)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C119(0.81); C835(0.93); C202(0.94); C611(1.04)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C202(0.81); C119(0.91); C611(0.98); C610(1.06)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C202(1.03); C119(1.15); C610(1.26); C835(1.31)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C119(0.78); C611(0.93); C835(0.98); C610(1.01)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C119(0.91); C611(1.00); C835(1.06); C607(1.06)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C119(0.90); C202(1.35); C607(1.10); C610(1.00)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C119(0.81); C202(1.17); C607(1.16); C610(1.09)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C119(0.87); C202(1.19); C607(1.11); C610(1.07)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C119(0.81); C202(0.96); C607(1.18); C610(1.13)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C119(0.91); C202(0.84); C607(1.13); C610(1.14)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C119(0.99); C202(0.98); C610(0.91); C611(0.92)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C119(0.99); C202(1.18); C607(0.85); C610(0.96)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C119(0.88); C202(1.07); C607(0.94); C610(0.90)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C119(0.93); C202(0.95); C607(0.65); C610(0.74)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C119(0.87); C202(0.81); C607(0.76); C610(0.88)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C119(0.98); C202(0.91); C607(0.79); C610(1.03)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C119(0.87); C202(0.94); C607(0.89); C610(1.01)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C119(0.88); C202(0.92); C607(0.86); C610(1.04)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C119(0.97); C202(1.00); C607(1.07); C610(1.12)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C119(0.87); C202(0.96); C607(0.80); C610(0.87)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C119(0.90); C202(0.83); C610(1.03); C611(1.03)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C119(0.88); C202(0.81); C607(0.81); C610(0.88)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C119(0.87); C202(0.96); C607(0.89); C610(0.98)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C119(1.20); C202(0.85); C607(0.99); C610(1.01)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C119(0.99); C202(0.94); C607(0.90); C610(0.99)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C119(0.96); C202(0.98); C607(0.59); C610(0.82)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C119(1.03); C202(0.88); C607(0.73); C610(0.88)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C119(0.92); C202(0.93); C607(1.32); C610(1.09)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C119(0.88); C202(0.87); C607(0.98); C610(1.01)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C119(0.86); C202(0.95); C607(1.07); C610(1.01)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C119(1.31); C202(0.98); C607(1.14); C610(1.18)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C119(0.99); C202(1.03); C610(1.01); C611(0.99)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C119(0.91); C202(0.99); C607(1.21); C610(1.24)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C119(1.02); C202(0.96); C607(1.21); C610(1.20)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C119(0.89); C202(0.95); C607(1.30); C610(1.28)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C119(0.79); C202(0.97); C607(1.14); C610(1.09)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C119(0.89); C202(0.92); C607(1.32); C610(1.29)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C119(1.05); C202(1.15); C607(1.31); C610(1.15)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C119(0.95); C202(0.99); C607(1.13); C610(1.03)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C119(0.95); C202(0.91); C607(1.19); C610(1.24)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C119(0.97); C202(0.92); C607(1.02); C610(1.26)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C119(1.00); C202(0.97); C607(0.94); C610(1.05)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C119(0.97); C202(0.83); C610(0.90); C611(0.91)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C119(1.00); C202(0.92); C607(0.90); C610(1.03)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C202(0.83); C607(0.81); C610(0.88); C611(0.79)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C202(0.82); C607(0.90); C610(0.90); C611(0.81)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C202(0.76); C607(0.89); C610(0.83); C611(0.82)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C202(0.84); C607(0.75); C610(0.80); C611(0.75)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C202(0.86); C607(0.87); C610(0.88); C611(0.87)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C202(0.80); C607(0.93); C610(0.88); C611(0.83)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C202(0.90); C607(0.75); C610(0.75); C611(0.78)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C202(0.72); C607(0.87); C610(0.85); C611(0.83)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C202(0.74); C607(0.84); C610(0.87); C611(0.80)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C119(1.01); C202(0.87); C610(0.87); C611(0.86)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C202(0.79); C607(0.92); C610(0.88); C611(0.88)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C202(0.79); C607(0.78); C610(0.76); C611(0.78)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C202(0.98); C607(0.88); C610(0.94); C611(0.90)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C202(0.73); C607(0.76); C610(0.86); C611(0.79)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C202(0.81); C607(0.92); C610(0.89); C611(0.84)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C119(0.97); C202(1.03); C607(0.90); C610(0.97)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C119(1.06); C202(1.00); C607(0.86); C610(0.94)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C119(0.95); C202(1.00); C607(0.87); C610(0.94)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C119(1.02); C202(1.02); C607(0.77); C610(0.98)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C119(1.01); C202(0.92); C610(0.92); C611(0.91)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C119(1.11); C202(1.10); C607(0.94); C610(0.99)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C119(1.03); C202(1.07); C607(0.81); C610(1.00)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C119(1.28); C202(1.08); C607(0.82); C610(1.08)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C119(1.17); C202(1.06); C607(0.77); C610(0.89)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C119(1.10); C202(0.99); C607(1.03); C610(1.03)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C119(1.06); C202(1.11); C607(0.82); C610(0.98)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C119(1.16); C202(1.15); C607(0.72); C610(0.98)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C119(1.25); C202(1.25); C607(0.75); C610(0.88)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C119(1.19); C202(1.19); C607(0.88); C610(1.02)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C119(1.24); C202(1.19); C607(1.00); C610(1.11)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C119(1.01); C202(0.91); C610(0.81); C611(0.83)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C119(1.13); C202(0.97); C607(0.89); C610(1.11)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C119(0.95); C202(1.09); C607(0.92); C610(1.08)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C119(0.89); C202(1.09); C607(0.73); C610(0.80)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C119(1.02); C202(1.15); C607(0.85); C610(0.89)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C119(0.90); C202(0.82); C607(0.77); C610(0.88)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C119(0.88); C202(0.95); C607(0.84); C610(0.99)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C119(0.92); C202(0.94); C607(0.81); C610(0.89)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C119(0.89); C202(0.84); C607(0.91); C610(0.95)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C119(0.90); C202(0.92); C607(0.72); C610(0.88)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C119(0.95); C202(0.97); C607(0.85); C610(0.95)  LDD0811  [6]
 LDCM0634  CY-0357 Hep-G2 C966(0.60)  LDD2228  [12]
 LDCM0495  E2913 HEK-293T C667(0.71); C202(0.75); C509(1.07); C119(0.85)  LDD1698  [24]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C119(4.99)  LDD1702  [4]
 LDCM0625  F8 Ramos C119(0.56); C202(1.18); 0.82; C966(1.35)  LDD2187  [25]
 LDCM0572  Fragment10 Ramos C119(0.62); C202(0.70); 1.12; C966(1.61)  LDD2189  [25]
 LDCM0573  Fragment11 Ramos C119(1.79); C202(0.15); 0.84; C966(10.05)  LDD2190  [25]
 LDCM0574  Fragment12 Ramos C119(0.88); C202(1.01); 1.23; C966(1.15)  LDD2191  [25]
 LDCM0575  Fragment13 Ramos C119(1.05); C202(0.93); 1.08; C966(1.16)  LDD2192  [25]
 LDCM0576  Fragment14 Ramos C119(0.74); C202(1.02); 1.52; C966(0.70)  LDD2193  [25]
 LDCM0579  Fragment20 Ramos C119(0.94); C202(1.01); 1.49; C966(1.39)  LDD2194  [25]
 LDCM0580  Fragment21 Ramos C119(0.97); C202(0.90); 0.78; C966(0.81)  LDD2195  [25]
 LDCM0582  Fragment23 Ramos C119(1.26); C202(0.89); 1.81; C966(2.09)  LDD2196  [25]
 LDCM0578  Fragment27 Ramos C119(1.04); C202(0.87); 0.95; C966(1.00)  LDD2197  [25]
 LDCM0586  Fragment28 Ramos C119(0.64); C202(0.70); 1.38; C966(0.89)  LDD2198  [25]
 LDCM0588  Fragment30 Ramos C119(1.11); C202(1.08); 0.88; C966(1.61)  LDD2199  [25]
 LDCM0589  Fragment31 Ramos C119(1.04); C202(1.00); 1.37; C966(1.42)  LDD2200  [25]
 LDCM0590  Fragment32 Ramos C119(0.59); C202(0.62); 0.85; C966(1.51)  LDD2201  [25]
 LDCM0468  Fragment33 HCT 116 C202(0.71); C607(0.90); C610(0.83); C611(0.84)  LDD0785  [6]
 LDCM0596  Fragment38 Ramos C119(1.06); C202(0.91); 0.95; C966(1.47)  LDD2203  [25]
 LDCM0566  Fragment4 Ramos C119(0.87); C202(1.00); 1.47; C966(0.98)  LDD2184  [25]
 LDCM0427  Fragment51 HCT 116 C119(1.11); C202(0.90); C607(1.02); C610(1.05)  LDD0744  [6]
 LDCM0610  Fragment52 Ramos C119(2.84); C202(1.20); 1.55; C966(2.49)  LDD2204  [25]
 LDCM0614  Fragment56 Ramos C119(1.29); C202(1.33); 1.29; C966(1.78)  LDD2205  [25]
 LDCM0569  Fragment7 Ramos C119(0.60); C202(0.87); 0.91; C966(1.41)  LDD2186  [25]
 LDCM0571  Fragment9 Ramos C119(1.29); C202(1.30); 1.84; C966(1.39)  LDD2188  [25]
 LDCM0107  IAA HeLa C509(0.00); H286(0.00); H268(0.00); C843(0.00)  LDD0221  [17]
 LDCM0022  KB02 HCT 116 C610(4.28); C611(4.28); C835(2.92); C843(2.92)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C610(19.42); C611(19.42); C835(1.85); C843(1.85)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C610(20.00); C611(20.00); C835(3.20); C843(3.20)  LDD0082  [6]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C202(0.72)  LDD2121  [4]
 LDCM0109  NEM HeLa H286(0.00); H268(0.00)  LDD0223  [17]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C202(0.80)  LDD2089  [4]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C202(0.95)  LDD2093  [4]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C202(0.96); C119(1.14)  LDD2099  [4]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C202(1.07)  LDD2107  [4]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C202(0.56); C119(0.74)  LDD2109  [4]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C202(0.53)  LDD2118  [4]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C202(1.64)  LDD2119  [4]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C202(0.83)  LDD2120  [4]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C202(0.30)  LDD2122  [4]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C202(0.66); C119(1.08)  LDD2123  [4]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C202(0.27)  LDD2124  [4]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C202(0.72)  LDD2125  [4]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C202(0.87); C119(0.96)  LDD2127  [4]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C202(1.08); C119(1.10); C883(1.49)  LDD2129  [4]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C202(0.59)  LDD2133  [4]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C202(1.32)  LDD2135  [4]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C202(1.28)  LDD2136  [4]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C202(0.66)  LDD2137  [4]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C202(1.97)  LDD1700  [4]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C119(1.07)  LDD2140  [4]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C202(0.88)  LDD2143  [4]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C202(1.98)  LDD2144  [4]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C202(0.83); C119(0.54)  LDD2146  [4]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C202(2.03)  LDD2147  [4]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C202(0.38)  LDD2149  [4]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C119(0.58)  LDD2150  [4]
 LDCM0627  NUDT7-COV-1 HEK-293T C843(0.56)  LDD2206  [26]
 LDCM0628  OTUB2-COV-1 HEK-293T C843(0.90)  LDD2207  [26]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Condensin complex subunit 1 (NCAPD2) CND1 (condensin subunit 1) family Q15021
Condensin complex subunit 2 (NCAPH) CND2 (condensin subunit 2) family Q15003

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20. ACS Med Chem Lett. 2022 Sep 26;13(10):1648-1654. doi: 10.1021/acsmedchemlett.2c00336. eCollection 2022 Oct 13.
3 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
8 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
9 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
10 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
11 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647
12 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
13 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
14 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
15 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
16 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
17 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
18 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
19 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
20 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
21 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
22 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
23 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
24 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
25 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
26 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.